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Researcher Shows Chemicals Alter Male Reproductive System

Tuesday, February 19th, 2008

(Beyond Pesticides, February 19, 2008) Common household chemicals and widespread pollutants are changing male reproductive health and impacting sexual function, development and cancer rates of today’s generations and possibly their offspring, according to more than 15 years of research by a Colorado State University expert. For example, one study looking at sperm counts globally from 1940, when chemicals first began to be widely produced, to the 1990s, indicates a 1.15 percent per year decline in sperm counts. These declines may be linked to chemical exposure.Rao Veeramachaneni, BVSc, MScVet, PhD, a biomedical sciences professor in the College of Veterinary Medicine and Biomedical Sciences, has found that chemicals including pesticides, common pollutants in ground water, and chemicals in plastics, make-up and nail polish are on a growing list of culprits causing developmental abnormalities such as impaired sperm quality and impotence. Reproductive health can be compromised if males are exposed at various times in life spanning from in utero up to adulthood.Dr. Veeramachaneni’s findings span the globe and are across species lines, from humans to horses, wildlife to frogs. His research, coupled with the collective findings of other experts in the field, indicates a strong link related to pollutants, and incidence of such […]

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Antibacterial Found in Plasma and Milk of Swedish Nursing Mothers

Tuesday, January 22nd, 2008

(Beyond Pesticides, January 22, 2008) Triclosan, a very common antibacterial chemical, is present in the plasma and breast milk of nursing mothers, according to a study by Swedish researchers. Every one of the 36 mothers tested positive for triclosan levels in their bodies, and the concentrations were clearly and significantly higher in the exposed group (i.e., those that use triclosan-containing products) than in the control group. This does not come as a surprise since triclosan is widely used in personal care products””including soaps, deodorants, and toothpaste””as well as plastics and textiles. Although there was high variability within groups, even members of the control group had triclosan present in their plasma, indicating that there are other significant sources of exposure outside of hygiene products. Triclosan is not removed from wastewater by conventional treatment processes and has been found in both wastewater effluent and sewage sludge. The authors of Triclosan in plasma and milk from Swedish nursing mothers and their exposure via personal care products say that the significance of the presence of triclosan in plasma and breast milk of nursing mothers is not easily deduced and that the health effects, especially the long-term effects of chronic exposure, of triclosan are not […]

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Scientists Cite Pesticides’ Multigeneration Effects, Call for Regulation

Thursday, October 18th, 2007

(Beyond Pesticides, October 18, 2007) In a scholarly review written by Theo Colborn, Ph.D. and Lynn Carroll, Ph.D., the authors point to the multigenerational effects of some pesticides that they say demand improved regulation to protect human and environmental health. The review, “Pesticides, Sexual Development, Reproduction, and Fertility: Current Perspective and Future Direction,” appears in the international journal Human and Ecological Risk Assessment (13:5, 1078 — 1110), September, 2007. The study points out a major deficiency in the U.S. Environmental Protection Agency’s regulation of pesticides under current health reviews and risk assessments. The authors call EPA’s pesticide registration system “outmoded” and one that has “almost completely missed the low-dose and endocrine system-mediated effects of pesticides.” The study reviews both epidemiological and laboratory data. In the abstract, the authors state the following: Improvements in chemical analytical technology and non-invasive sampling protocols have made it easier to detect pesticides and their metabolites at very low concentrations in human tissues. Monitoring has revealed that pesticides penetrate both maternal and paternal reproductive tissues and organs, thus providing a pathway for initiating harm to their offspring starting before fertilization throughout gestation and lactation. This article explores the literature that addresses the parental pathway of exposure […]

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Chloropicrin Fumes Send Nevada Farmworkers to Hospital

Tuesday, October 9th, 2007

(Beyond Pesticides, October 9, 2007) Two state agencies and the U.S. EPA are close to completing an investigation of the poisoning of over 100 farmworkers in Nevada two weeks ago. Chloropicrin, an agricultural fumigant, drifted to a worker-occupied field, sending 121 laborers to Saint Lyon Medical Center (SLMC) for treatment on the morning of September 26. Upon arrival, the workers were showing symptoms including difficulty breathing, nausea, watery eyes and sore throat. SLMC Administrator Joan Hall said that only 12 of the 121 people required emergency room care, and most returned to work the same afternoon. Normally, chloropicrin’s off-gas dissipates, but because of a weather inversion the fumigant stayed lower to the ground and drifted more than a half-mile away from its application area to the worker-occupied field. Speaking on behalf of local farming operation Peri & Sons Farms, media contact Tim Cummings said both the Nevada Department of Agriculture and Occupational Safety and Health Administration have concluded their portion of the report, with the remaining piece due from the EPA. Peri & Sons owns both fields, which are located just over a half-mile apart, far enough apart from each other for such applications, according to state regulations and the […]

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EPA Expected To Allow Toxic Fumigant for Agriculture

Friday, September 28th, 2007

(Beyond Pesticides, September 28, 2007) EPA is due to make a decision on methyl iodide, a highly reactive and carcinogenic chemical, for use in crop production as a soil fumigant. Scientists across the country are alarmed by the prospect of registering methyl iodide as a pesticide, and fifty-four chemists and physicians from across the country issued a letter to EPA Administrator Stephen Johnson Monday urging the Agency not to sanction the broad use of methyl iodide now or at any time.“[W]e are concerned that pregnant women and the fetus, children, the elderly, farm workers, and other people living near application sites would be at serious risk if methyl iodide is permitted for use in agriculture,” said the group in the letter. In the chemical community methyl iodide is a well-known cancer hazard due to its ability to mutate DNA, and the scientists are fearful that methyl iodide’s high volatility and water solubility will expose many people to harm if the chemical is used in agriculture. Methyl iodide and methyl bromide are injected into the soil at rates of 100-400 pounds per acre to kill soil-borne pests. Because of the high application rates and gaseous nature of these chemicals, they drift […]

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Members of Congress Push EPA To Act on Endocrine Disruptors

Monday, September 24th, 2007

(Beyond Pesticides, September 24, 2007) Seven representatives wrote to the EPA last Thursday, urging the government agency to act promptly to identify and screen products for dangerous endocrine-disrupting chemicals. The letter asks EPA Administrator Stephen Johnson to provide definite deadlines in the testing and control of endocrine disruptors, which are substances that interfere with the normal functioning of the endocrine system, responsible for hormonal and developmental processes. EPA’s regulation of these substances that mimic or alter natural hormonal processes has been slow and lacks direction to meet set goals promptly, according to the U.S. Representatives. “To date, EPA’s efforts in this area have been characterized by missed deadlines, prolonged delays, and inadequate incorporation of public input,” according to the letter from the House Committee on Oversight and Government Reform, chaired by Rep. Henry Waxman (D-California). Ranking Minority Member on the Committee Tom Davis (R-Virginia); Representatives Elijah Cummings (D-Maryland), Chris Van Hollen (D-Maryland), Wayne Gilchrest (R-Maryland), and Jim Moran (D-Virginia); and Delegate Eleanor Holmes Norton (D-D.C.) also signed the letter to EPA. Advocates say that EPA’s lack of urgency on endocrine disruptors leaves the American population and future generations at risk for adverse health effects from exposure to these substances through […]

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Study Finds Frogs Near Agricultural Fields More Likely To Be Deformed

Thursday, August 2nd, 2007

(Beyond Pesticides, August 2, 2007) According to the Associated Press (AP), a new study finds frogs in Vermont living near farms are more than twice as likely as those living elsewhere to have deformities like missing legs. Yale University ecologist David Skelly, Ph.D., told the AP he decided to look at Vermont frogs because the state has been a hot spot during the last 10 years for deformed frogs. “We went to all these wetlands and cataloged where the deformities were found, and what kind of landscapes seemed to pose higher risks, if any,” Dr. Skelly said. “The answer was, frogs growing up in proximity to agriculture were more than two times as likely to have deformities. This doesn’t say it is chemical pesticides, but you can’t credibly consider this problem of the frogs without at least evaluating whether pesticides are involved.” Richard Levey, a biologist with the Vermont Agency of Natural Resources, said two common farm chemicals, atrazine and metolachlor, had been found in trace amounts in water from wetlands where deformed frogs had been found. But he told the AP that the concentrations were far below those thought to have any effect on aquatic life. Research by Tyrone […]

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Climate Change and Pesticides Hot Issue for Fish

Monday, July 23rd, 2007

(Beyond Pesticides, July 23, 2007) New research finds several species of freshwater fish have lower temperature tolerances when exposed to the widely used pesticides endosulfan and chlorpyrifos. The discovery reveals another key pesticides issue in the global warming debate. The study, “The Effects of Three Organic Chemicals on the Upper Thermal Tolerances of Four Freshwater Fishes” (Environmental Toxicology and Chemistry, July 2007), is the work of Ronald Patra of Australia’s Department of Environment and Conservation and colleagues. The study establishes the upper temperature tolerances of both unexposed and exposed silver perch, eastern rainbowfish, western carp gudgeon and rainbow trout. Exposed fish were given sublethal doses of endosulfan, chlorpyrifos or phenol. The results show exposure to endosulfan cause a decrease of temperature tolerance in silver perch by 2.8 °C, eastern rainbowfish 4.1 °C, western carp gudgeon 3.1 °C, and rainbow trout 4.8 °C. Chlorpyrifos decreases temperature tolerance in silver perch by 3.8 °C, eastern rainbowfish 2.5 °C, western carp gudgeon 4.3 °C, and rainbow trout 5.9 °C. Phenol is not shown to cause a significant decrease in tolerance. The authors conclude, “The reduction in thermal tolerance of fish in the presence of endosulfan and chlorpyrifos suggest that, not only does temperature […]

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As Honeybee Die-off Continues, Scientists Investigate Pesticide Link

Tuesday, June 19th, 2007

(Beyond Pesticides, June 19, 2007) Scientists investigating a mysterious die-off of many of the nation’s honeybees are concentrating on pesticides and microorganisms as possible causes of the disorder, and some beekeepers are refusing to place their hives near chemically treated fields out of fear that pesticides may be contributing to the die-off. Scientists from Penn State University and the U.S. Department of Agriculture are leading the research into the disease, which has killed tens of thousands of bee colonies in at least 35 states. The die-off has threatened the livelihood of commercial beekeepers and strained fruit growers and other farmers who rely on bees to pollinate more than 90 flowering crops, including apples, nuts and citrus trees. After months of study, researchers cannot tie the ailment to any single factor. But scientists have zeroed in on a new, unnamed pathogen found in the dead bees, and on the role of pesticides, said Maryann Frazier, a senior extension associate in the university’s entomology department. David Hackenberg was the first beekeeper to report the disorder to Penn State last fall after losing nearly 75 percent of his 3,200 colonies. He has since rebuilt his business to 2,400 colonies, but now asks growers […]

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Study Sheds Light on Pesticides’ Link to Parkinson’s Disease

Thursday, February 8th, 2007

(Beyond Pesticides, February 8, 2007) Investigators at St. Jude Children’s Research Hospital have shed new light on the suspected role of pesticides in the development of Parkinson’s disease (PD). The study, “GST expression mediates dopaminergic neuron sensitivity in experimental parkinsonism” appearing in the Proceedings of the National Academy of Sciences (January 31, 2007), illustrates the mechanism of nerve cell damage by pesticide exposure. The enzyme that prevents damage to the substantia nigra, the part of the brain where nerve cell damage associated with PD occurs, is called GST pi (“pie”). This enzyme stands like a sentry at the crossroads of several biochemical pathways, any one of which can lead to PD. GST pi protects the nerve cell from death caused by either environmental toxics, such as pesticides, or a self-destruction process called apoptosis (cell suicide), triggered by certain stressful conditions in the cell. If GST pi levels are reduced or this enzyme is overwhelmed by toxics, these nerves are at increased risk of death, according to studies in mouse models. GST pi is one of a family of similar enzymes that eliminate free radicals generated by pesticides and other chemicals. Two members of this family are present in the brain, […]

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