{"id":16686,"date":"2015-10-05T00:01:13","date_gmt":"2015-10-05T04:01:13","guid":{"rendered":"http:\/\/beyondpesticides.org\/dailynewsblog\/?p=16686"},"modified":"2015-10-05T10:01:19","modified_gmt":"2015-10-05T14:01:19","slug":"yale-study-links-prenatal-pesticide-exposure-to-tremors-in-children","status":"publish","type":"post","link":"https:\/\/beyondpesticides.org\/dailynewsblog\/2015\/10\/yale-study-links-prenatal-pesticide-exposure-to-tremors-in-children\/","title":{"rendered":"Yale Study Links Prenatal Pesticide Exposure to Tremors in Children"},"content":{"rendered":"

(Beyond Pesticides,<\/em> October 05, 2015) According to a Yale University study, prenatal exposure to the widely used agricultural pesticide chlorpyrifos<\/a> is linked to tremors \u2014 involuntary contraction or twitching of muscles \u2014 in childhood. Chlorpyrifos, a broad-spectrum chlorinated organophosphate insecticide also known as Dursban, may also affect the cardiovascular and respiratory systems and is acutely toxic to bees, birds, mammals, and aquatic life.<\/p>\n

\"pregnant-original\"<\/a>The study, titled Prenatal exposure to the organophosphate pesticide chlorpyrifos and childhood tremor<\/a> \u00a0and published in the journal Neurotoxicology<\/em>, measured the presence of chlorpyrifos in umbilical cord blood samples in 263 low-income, inner-city minority children. In 2001, the U.S. Environmental Protection Agency (EPA) banned residential use of chlorpyrifos, which was prominent in urban areas at the time. However, the study participants \u00a0\u2014263 minority mothers \u00a0and their children, all from low income \u00a0communities in New York \u00a0City\u2014 were assembled in 1997, \u00a0before the ban was imposed. In \u00a01997, the initial measure of each \u00a0child\u2019s prenatal exposure to CPF \u00a0was taken from umbilical cord \u00a0blood. The children were then followed until approximately 11 years of age, after which they underwent a neurophysical assessment, which included a short drawing test. Researchers found that compared to all other children, those who had relatively high levels of prenatal chlorpyrifos exposure were significantly more likely to exhibit mild or mild to moderate tremor in one or both arms. The study is just one of many suggesting that pesticide exposure is associated with adverse neuro-developmental issues.<\/p>\n

\u201cThis is perhaps one of the \u00a0only examples in which we can \u00a0show that in utero exposure to \u00a0these pesticides leads to long-term \u00a0health care consequences in \u00a0the children,\u201d said Yale senior author \u00a0and School of Medicine neurology \u00a0professor Elan Louis, MD, to Yale Daily News<\/em>. \u00a0 \u00a0\u201cWe\u2019re talking about the \u00a0possibility that fetuses exposed to \u00a0pesticides through their mother, \u00a0while they\u2019re in utero, could have \u00a0tremors eight or ten years later.\u201d<\/p>\n

Among experts who commented \u00a0on Louis\u2019 findings, as well \u00a0as Louis himself, there was a general \u00a0consensus that this study \u00a0points toward a need for the agricultural \u00a0industry \u201d\u201d the main setting \u00a0in which chlorpyrifos is found today \u00a0\u201d\u201d to reconsider their use of pesticides.<\/p>\n

According to Louis, his next \u00a0step is to fully finish assessing the \u00a0results of the study. In addition \u00a0to taking drawing tests, the children \u00a0participating in the study \u00a0had MRI scans, which Louis and \u00a0his colleagues plan to analyze for \u00a0\u201cstructural or metabolic changes \u00a0in certain brain regions,\u201d to further \u00a0investigate the brain damage \u00a0caused by chlorpyrifos.<\/p>\n

Chlorpyrifos<\/a> \u00a0is highly \u00a0neurotoxic. It is a cholinesterase inhibitor, which means that it can bind irreversibly to acetylcholine esterase (AchE), an essential enzyme for normal nerve impulse transmission, inactivating the enzyme. Studies have documented that exposure to even low levels of organophosphates like chlorpyrifos during pregnancy \u00a0can impair learning<\/a>, change brain function, and alter thyroid levels of offspring into adulthood. The evidence of the neurotoxic dangers associated with chlorpyrifos\u2019 exposure is extensive and consistent<\/a>.<\/p>\n

In 2000, EPA administrator \u00a0Carol Browner announced<\/a> \u00a0a voluntary agreement between the agency and industry leaders, including Dow AgroSciences, to ban all home and garden uses of Dursban, which was at the time the most widely used household pesticide in the U.S. This agreement, however, did not include agricultural, golf course, or public mosquito spraying uses. It continues to be heavily used today with an estimated 5 million pounds applied in the U.S. annually, releasing its toxins onto our food and into the lives of farmworkers \u00a0<\/a>and their \u00a0children<\/a>. \u00a0In 2012, EPA \u00a0imposed \u201cno-spray\u201d buffer zones<\/a> \u00a0around public spaces, including recreational areas, schools, and homes to reduce bystander exposure risks. In spite of these restrictions, chlorpyrifos still poses risks to human and environmental health. Earlier this year<\/a>, a federal appeals court judge mandated that EPA respond to a petition filed nearly nine years ago that seeks \u00a0to force the agency to restrict chlorpyrifos<\/a>. EPA must meet an October 31 deadline and establish a timeline for finalizing the proposed rule if they decide on a ban.<\/p>\n

Chlorpyrifos leads a list of numerous toxic chemicals that are central to chemical-intensive agricultural practices that threaten \u00a0health and the environment effects. While a ban is \u00a0certainly important \u00a0as current inaction \u00a0reflects a breakdown in the \u00a0regulatory process, ultimately the widespread adoption of \u00a0organic management<\/a> \u00a0is necessary to protect consumers and the environment in the long-term. Beyond Pesticides has long sought a broad-scale marketplace transition to organic practices that disallows the use of toxic synthetic pesticides by law and encourages a systems-based approach that is protective of health and the environment. Even at its worst, this approach never allows the use of highly toxic synthetic pesticides, let alone organophosphates such as chlorpyrifos, and advances \u00a0a \u00a0viable, scalable<\/a> \u00a0path forward for growing food.<\/p>\n

For more information on chlorpyrifos and other pesticides used in homes, schools, workplaces and communities, see Beyond Pesticides’ Gateway on Pesticide Hazards and Safe Pest Management<\/a>. For alternatives strategies on specific pest problems, check out ManageSafe<\/a>.<\/p>\n

Source: Yale Daily News<\/a><\/p>\n

All unattributed positions and opinions in this piece are those of Beyond Pesticides.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

(Beyond Pesticides, October 05, 2015) According to a Yale University study, prenatal exposure to the widely used agricultural pesticide chlorpyrifos is linked to tremors \u2014 involuntary contraction or twitching of muscles \u2014 in childhood. Chlorpyrifos, a broad-spectrum chlorinated organophosphate insecticide also known as Dursban, may also affect the cardiovascular and respiratory systems and is acutely toxic to bees, birds, mammals, and aquatic life. The study, titled Prenatal exposure to the organophosphate pesticide chlorpyrifos and childhood tremor \u00a0and published in the journal Neurotoxicology, measured the presence of chlorpyrifos in umbilical cord blood samples in 263 low-income, inner-city minority children. In 2001, the U.S. Environmental Protection Agency (EPA) banned residential use of chlorpyrifos, which was prominent in urban areas at the time. However, the study participants \u00a0\u2014263 minority mothers \u00a0and their children, all from low income \u00a0communities in New York \u00a0City\u2014 were assembled in 1997, \u00a0before the ban was imposed. In \u00a01997, the initial measure of each \u00a0child\u2019s prenatal exposure to CPF \u00a0was taken from umbilical cord \u00a0blood. The children were then followed until approximately 11 years of age, after which they underwent a neurophysical assessment, which included a short drawing test. Researchers found that compared to all other children, those who […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21,33,293,3],"tags":[],"class_list":["post-16686","post","type-post","status-publish","format-standard","hentry","category-chemicals","category-chlorpyrifos","category-developmental-disorders","category-diseasehealth-effects"],"yoast_head":"\nYale Study Links Prenatal Pesticide Exposure to Tremors in Children - Beyond Pesticides Daily News Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2015\/10\/yale-study-links-prenatal-pesticide-exposure-to-tremors-in-children\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Yale Study Links Prenatal Pesticide Exposure to Tremors in Children - Beyond Pesticides Daily News Blog\" \/>\n<meta property=\"og:description\" content=\"(Beyond Pesticides, October 05, 2015) According to a Yale University study, prenatal exposure to the widely used agricultural pesticide chlorpyrifos is linked to tremors \u2014 involuntary contraction or twitching of muscles \u2014 in childhood. 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