{"id":20361,"date":"2017-04-04T08:32:28","date_gmt":"2017-04-04T12:32:28","guid":{"rendered":"http:\/\/beyondpesticides.org\/dailynewsblog\/?p=20361"},"modified":"2017-04-04T08:32:28","modified_gmt":"2017-04-04T12:32:28","slug":"pyrethroid-insecticides-cause-premature-puberty-boys","status":"publish","type":"post","link":"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/","title":{"rendered":"Pyrethroid Insecticides Cause Premature Puberty in Boys"},"content":{"rendered":"<p>(<em>Beyond Pesticides<\/em>, April 4, 2017) Exposure to commonly used pyrethroid insecticides results in the early onset of puberty in boys, according to a <a href=\"https:\/\/plan.core-apps.com\/tristar_endo17\/abstract\/9f6300891abea35983bbd25dffdbab7a\">study presented at the 99<sup>th<\/sup> meeting of the Endocrine Society<\/a> in Orlando, Florida this week. Pyrethroids, which exhibit <a href=\"https:\/\/www.beyondpesticides.org\/resources\/pesticide-induced-diseases-database\/endocrine-disruption\">endocrine disrupting<\/a> properties, have the ability to interfere with the proper regulation of the human body\u2019s hormonal system. This research is the first to investigate not only the association between pyrethroids and accelerated puberty, but also the causal mechanisms involved in the physiological changes taking place within the human body.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-20367 size-medium\" style=\"margin: 3px;\" src=\"http:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2017\/04\/large_Endocrine_Society-300x247.png\" alt=\"\" width=\"300\" height=\"247\" srcset=\"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2017\/04\/large_Endocrine_Society-300x247.png 300w, https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2017\/04\/large_Endocrine_Society.png 512w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>For the study, Jing Liu, PhD, and colleagues from Zhejuang University in China, analyzed the urine in 463 Chinese boys aged 9 to 16 for the presence of metabolites from the pyrethroid insecticide <a href=\"https:\/\/www.beyondpesticides.org\/resources\/pesticide-gateway?pesticideid=21\">cypermethrin<\/a>. Results show that a 10% increase in the metabolite 3-PBA is associated with a roughly 4% increase in luteinizing and follicle-stimulating hormones, which facilitate puberty and sperm production. The author\u2019s note that, \u201cBoys with increased urinary levels of 3-PBA have a significantly increased risk of earlier pubertal onset, in which the odds of being in an advanced pubertal stage\u00a0are increase by 73% to 110%.\u201d<\/p>\n<p>The study, acknowledging the limitation in determining causality, further investigates the mechanism which gives rise to this development in laboratory studies using test tubes and rodents. Dr. Liu and his team found that the same process held up in rodent models, with cypermethrin accelerating puberty through hormonal release. Rather than a response from the hyperthalamus, which controls the release of pituitary luteinizing and follicle-stimulating hormones, scientists found that cypermethrin acts directly on cells within the testis and pituitary glands.<\/p>\n<p>&#8220;This is the first study to provide evidence that environmental exposure to pyrethroids. . .is associated with measurable effects on male pubertal development. Given the growing use of pyrethroid insecticides, we must prudently assess these chemicals for their risks to children&#8217;s health,&#8221; Dr. Liu indicated in a statement to <a href=\"http:\/\/www.medscape.com\/viewarticle\/878085\">Medscape<\/a>.<\/p>\n<p>Given recent data on the <a href=\"http:\/\/beyondpesticides.org\/dailynewsblog\/2014\/02\/chlidren-exposed-to-increasing-concentrations-of-pyrethroid-insecticides\/\">rise in use of these chemicals for household pest control<\/a>, both researchers and advocates are concerned about the range of implications these chemicals could be having on young children in the U.S. and abroad. Previous research finds these chemicals are associated with behavioral problems in children, including <a href=\"http:\/\/beyondpesticides.org\/dailynewsblog\/2017\/03\/common-household-pesticides-linked-behavioral-problems-children\/\">externalizing and internalizing disorders<\/a>, <a href=\"http:\/\/beyondpesticides.org\/dailynewsblog\/2015\/02\/commonly-used-pyrethroid-pesticide-increases-risk-of-adhd\/\">ADHD<\/a>, and <a href=\"http:\/\/beyondpesticides.org\/dailynewsblog\/2011\/02\/study-links-prenatal-exposure-to-pyrethroid-insecticides-and-learning-problems\/\">delayed cognitive and motor development<\/a>. \u00a0Proximity to heavy use of these chemicals in agriculture is associated with an <a href=\"http:\/\/beyondpesticides.org\/dailynewsblog\/2014\/06\/close-proximity-to-pesticide-treated-fields-increases-risk-of-autism\/\">87% increased risk of a child developing autism<\/a> when applied during pregnant mother\u2019s third trimester.<\/p>\n<p>Pyrethroids have also been linked to cancer in young children. Exposure to permethrin in utero is <a href=\"http:\/\/beyondpesticides.org\/dailynewsblog\/2013\/01\/risk-of-infant-leukemia-associated-with-mothers-pesticide-exposure\/\">linked to increased risk of infant leukemia<\/a> diagnosed before age two. In an interview with Medscape, Julie Ann Sosa, MD, a surgical oncologist and endocrine surgeon at Duke University Medical Center, said, \u201cWe need to understand that &#8216;progress&#8217; potentially comes with a cost. If we understand the cons, we can start to work on alternatives [that are safer].\u201d<\/p>\n<p>Beyond Pesticides continues to encourage alternatives to the use of toxic, endocrine disrupting pyrethroid chemicals for use in pest management. To manage home and garden pests, refer to the <a href=\"https:\/\/www.beyondpesticides.org\/resources\/managesafe\/choose-a-pest\">ManageSafe<\/a> tool, where you\u2019ll find strategies to fight the causes of a pest outbreak, rather than focus on the symptoms. For alternatives in controlling nuisance and public health mosquito outbreaks, see the <a href=\"https:\/\/www.beyondpesticides.org\/programs\/mosquitos-and-insect-borne-diseases\/overview\">Mosquito Management and Insect-Borne Diseases<\/a> webpage. And for agriculture, learn about <a href=\"https:\/\/www.beyondpesticides.org\/programs\/organic-agriculture\/why-organic\/health-benefits\">why organic<\/a>, which prohibits synthetic pyrethroids, is the right choice for you and your family when you shop. Lastly, to facilitate a community level conversion to safer practices, Beyond Pesticides has the <a href=\"https:\/\/www.beyondpesticides.org\/programs\/lawns-and-landscapes\/tools-for-change\">Tools for Change<\/a> needed to institute lasting protections.<\/p>\n<p>Source: <a href=\"https:\/\/plan.core-apps.com\/tristar_endo17\/abstract\/9f6300891abea35983bbd25dffdbab7a\">ENDO 2017<\/a>, <a href=\"http:\/\/www.medscape.com\/viewarticle\/878085\">Medscape<\/a><\/p>\n<p><em>All unattributed positions and opinions in this piece are those of Beyond Pesticides<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>(Beyond Pesticides, April 4, 2017) Exposure to commonly used pyrethroid insecticides results in the early onset of puberty in boys, according to a study presented at the 99th meeting of the Endocrine Society in Orlando, Florida this week. Pyrethroids, which exhibit endocrine disrupting properties, have the ability to interfere with the proper regulation of the human body\u2019s hormonal system. This research is the first to investigate not only the association between pyrethroids and accelerated puberty, but also the causal mechanisms involved in the physiological changes taking place within the human body. For the study, Jing Liu, PhD, and colleagues from Zhejuang University in China, analyzed the urine in 463 Chinese boys aged 9 to 16 for the presence of metabolites from the pyrethroid insecticide cypermethrin. Results show that a 10% increase in the metabolite 3-PBA is associated with a roughly 4% increase in luteinizing and follicle-stimulating hormones, which facilitate puberty and sperm production. The author\u2019s note that, \u201cBoys with increased urinary levels of 3-PBA have a significantly increased risk of earlier pubertal onset, in which the odds of being in an advanced pubertal stage\u00a0are increase by 73% to 110%.\u201d The study, acknowledging the limitation in determining causality, further investigates the [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[199,21,254,293,3,1],"tags":[],"class_list":["post-20361","post","type-post","status-publish","format-standard","hentry","category-biomonitoring","category-chemicals","category-cypermethrin","category-developmental-disorders","category-diseasehealth-effects","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Pyrethroid Insecticides Cause Premature Puberty in Boys - Beyond Pesticides Daily News Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pyrethroid Insecticides Cause Premature Puberty in Boys - Beyond Pesticides Daily News Blog\" \/>\n<meta property=\"og:description\" content=\"(Beyond Pesticides, April 4, 2017) Exposure to commonly used pyrethroid insecticides results in the early onset of puberty in boys, according to a study presented at the 99th meeting of the Endocrine Society in Orlando, Florida this week. Pyrethroids, which exhibit endocrine disrupting properties, have the ability to interfere with the proper regulation of the human body\u2019s hormonal system. This research is the first to investigate not only the association between pyrethroids and accelerated puberty, but also the causal mechanisms involved in the physiological changes taking place within the human body. For the study, Jing Liu, PhD, and colleagues from Zhejuang University in China, analyzed the urine in 463 Chinese boys aged 9 to 16 for the presence of metabolites from the pyrethroid insecticide cypermethrin. Results show that a 10% increase in the metabolite 3-PBA is associated with a roughly 4% increase in luteinizing and follicle-stimulating hormones, which facilitate puberty and sperm production. The author\u2019s note that, \u201cBoys with increased urinary levels of 3-PBA have a significantly increased risk of earlier pubertal onset, in which the odds of being in an advanced pubertal stage\u00a0are increase by 73% to 110%.\u201d The study, acknowledging the limitation in determining causality, further investigates the [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/\" \/>\n<meta property=\"og:site_name\" content=\"Beyond Pesticides Daily News Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/beyondpesticides\" \/>\n<meta property=\"article:author\" content=\"https:\/\/www.facebook.com\/beyondpesticides\/\" \/>\n<meta property=\"article:published_time\" content=\"2017-04-04T12:32:28+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2017\/04\/large_Endocrine_Society-300x247.png\" \/>\n<meta name=\"author\" content=\"Beyond Pesticides\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@ByondPesticides\" \/>\n<meta name=\"twitter:site\" content=\"@ByondPesticides\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Beyond Pesticides\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/\"},\"author\":{\"name\":\"Beyond Pesticides\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/person\/1b5c0a0981b549cc5b628770073031f4\"},\"headline\":\"Pyrethroid Insecticides Cause Premature Puberty in Boys\",\"datePublished\":\"2017-04-04T12:32:28+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/\"},\"wordCount\":614,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#organization\"},\"image\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/#primaryimage\"},\"thumbnailUrl\":\"http:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2017\/04\/large_Endocrine_Society-300x247.png\",\"articleSection\":[\"Biomonitoring\",\"Chemicals\",\"cypermethrin\",\"Developmental Disorders\",\"Disease\/Health Effects\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/\",\"url\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/\",\"name\":\"Pyrethroid Insecticides Cause Premature Puberty in Boys - 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The founders, who established Beyond Pesticides (originally as National Coalition Against the Misuse of Pesticides) as a nonprofit membership organization in 1981, felt that without the existence of such an organized, national network, local, state and national pesticide policy would become, under chemical industry pressure, increasingly unresponsive to public health and environmental concerns. Beyond Pesticides believes that people must have a voice in decisions that affect them directly. We believe decisions should not be made for us by chemical companies or by decision-makers who either do not have all of the facts or refuse to consider them. Learn more about our work, read A Year in Review\u20142021, our accomplishments are your victories! Beyond Pesticides seeks to protect healthy air, water, land, and food for ourselves and future generations. By forging ties with governments, nonprofits, and people who rely on these natural resources, we reduce the need for unnecessary pesticide use and protect public health and the environment. Beyond Pesticides provides hands-on services to the public and supports local action by: identifying and interpreting hazards; and, designing safe pest management programs. With the information provided by Beyond Pesticides, people may not only be able to make informed choices and adopt practices that protect themselves and their families from unnecessary exposure to pesticides, but they will be able to effect changes on community-wide pest management decisions and policies that govern pesticide use, such as pesticide uses in parks, schools, for community insect control and along roadsides. 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Pyrethroids, which exhibit endocrine disrupting properties, have the ability to interfere with the proper regulation of the human body\u2019s hormonal system. This research is the first to investigate not only the association between pyrethroids and accelerated puberty, but also the causal mechanisms involved in the physiological changes taking place within the human body. For the study, Jing Liu, PhD, and colleagues from Zhejuang University in China, analyzed the urine in 463 Chinese boys aged 9 to 16 for the presence of metabolites from the pyrethroid insecticide cypermethrin. Results show that a 10% increase in the metabolite 3-PBA is associated with a roughly 4% increase in luteinizing and follicle-stimulating hormones, which facilitate puberty and sperm production. The author\u2019s note that, \u201cBoys with increased urinary levels of 3-PBA have a significantly increased risk of earlier pubertal onset, in which the odds of being in an advanced pubertal stage\u00a0are increase by 73% to 110%.\u201d The study, acknowledging the limitation in determining causality, further investigates the [&hellip;]","og_url":"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/","og_site_name":"Beyond Pesticides Daily News Blog","article_publisher":"https:\/\/www.facebook.com\/beyondpesticides","article_author":"https:\/\/www.facebook.com\/beyondpesticides\/","article_published_time":"2017-04-04T12:32:28+00:00","og_image":[{"url":"http:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2017\/04\/large_Endocrine_Society-300x247.png","type":"","width":"","height":""}],"author":"Beyond Pesticides","twitter_card":"summary_large_image","twitter_creator":"@ByondPesticides","twitter_site":"@ByondPesticides","twitter_misc":{"Written by":"Beyond Pesticides","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/#article","isPartOf":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/"},"author":{"name":"Beyond Pesticides","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/person\/1b5c0a0981b549cc5b628770073031f4"},"headline":"Pyrethroid Insecticides Cause Premature Puberty in Boys","datePublished":"2017-04-04T12:32:28+00:00","mainEntityOfPage":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/"},"wordCount":614,"commentCount":0,"publisher":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#organization"},"image":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/#primaryimage"},"thumbnailUrl":"http:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2017\/04\/large_Endocrine_Society-300x247.png","articleSection":["Biomonitoring","Chemicals","cypermethrin","Developmental Disorders","Disease\/Health Effects"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/","url":"https:\/\/beyondpesticides.org\/dailynewsblog\/2017\/04\/pyrethroid-insecticides-cause-premature-puberty-boys\/","name":"Pyrethroid Insecticides Cause Premature Puberty in Boys - 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