{"id":29916,"date":"2021-09-23T00:01:37","date_gmt":"2021-09-23T04:01:37","guid":{"rendered":"https:\/\/beyondpesticides.org\/dailynewsblog\/?p=29916"},"modified":"2021-09-22T15:54:41","modified_gmt":"2021-09-22T19:54:41","slug":"study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure","status":"publish","type":"post","link":"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/","title":{"rendered":"Study Adds to 40 Year Analysis Linking Brain Cancer to Pesticide Exposure"},"content":{"rendered":"

(Beyond Pesticides<\/em>, September 23, 2021) A study by\u00a0Claremont Graduate University<\/a> finds exposure to agricultural pesticides increases brain cancer risk up to 20 percent. This study expands on a 1998 study evaluating brain cancer risk among the farm population using epidemiologic studies.<\/p>\n

The etiology (cause) of brain cancer is inconclusive for many forms, including glioma and meningioma. Brain cancer risk factors include family history and exposure to radiation. However, geographical variance in brain cancer incidents suggests environmental pollutants like pesticides contribute to risk. Various\u00a0research studies<\/a>\u00a0already note the adverse effects pesticide exposure has on the brain. These effects range from headaches and tumors to learning and developmental disabilities among children and adults. Although general cancer incidents are decreasing, brain and nervous system cancers are rising<\/a>. Therefore, studies like this highlight the need to reevaluate pesticide exposure limits for those working with or around agricultural chemicals to prevent chronic, deadly diseases. The study researchers note, \u201cThis comprehensive review and meta-analysis encompassing 42 years of the epidemiologic literature and updating two previous meta-analyses by 20 years supports an association between farming and brain cancer incidence and mortality.[…]Our analyses suggest that the elevated risk has been consistent over time, and the addition of newer studies (i.e., those published since 2000) does not change this conclusion.\u201d<\/p>\n

Researchers conducted a literature review using PubMed and Agricola databases to assess studies evaluating the relationship between farming and brain cancer. The researchers reviewed meta-analysis studies to harmonize findings published between January 1997 and August 2019. In total, researchers evaluated 52 different studies.<\/p>\n

The study results demonstrate that 77 percent of studies have a positive association between brain cancer and farming, with an elevated risk factor between 1.03 to 6.53 times. Therefore, the meta-risk analysis finds the brain cancer mortality\/morbidity rate to be 13 percent. According to demographic information, white farmers have the highest rate of brain cancer. However, those managing livestock, where insecticides are widely used, have higher rates of brain cancer incidents than those managing crops. Overall, farmers experiencing pesticide exposure have a greater than 20 percent increased risk of brain cancer. Although there are discrepancies among studies, evidence from the previous 40 years, including the 20 years evaluated in this study, supports associations between brain cancer and chemical pesticide exposure from farming.<\/p>\n

The nervous system is an integral part of the human body and includes the brain, spinal cord, a vast network of nerves and neurons. These components are responsible for many of our bodily functions\u2014from the senses to movement. However, exposure to chemical toxicants, like pesticides, may cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. The impacts of pesticides on the nervous system, including the brain, are hazardous, especially for chronically exposed individuals (e.g., farmers and farmworkers) or during critical windows of vulnerability and development (e.g., childhood, pregnancy). Mounting evidence over the past years shows that chronic exposure to sublethal (low) levels<\/a>\u00a0of pesticides adversely affects the central nervous system (CNS). Specifically, researchers identify agricultural chemical exposure as a cause of many adverse CNS impacts. In addition to CNS effects, pesticide exposure can impact a plethora of neurological diseases. For instance,\u00a0farmworkers<\/a>\u00a0and their children experience higher rates of neurological diseases from exposure to carcinogenic (cancer-causing) and neurotoxic compounds readily used in conventional, chemical-intensive agriculture. These diseases include\u00a0amyotrophic lateral sclerosis<\/a>\u00a0(ALS) and\u00a0Parkinson\u2019s disease<\/a>,\u00a0dementia<\/a>-like diseases such as\u00a0Alzheimer\u2019s<\/a>, and other effects on\u00a0cognitive function<\/a>. Therefore, advocates say it is essential to avoid toxic chemical exposure to lessen potential acute and chronic health risks.<\/p>\n

Pesticide use is widespread and direct exposure from applications or indirect exposure from residues pose a threat to human health. Children are more vulnerable to the impact of pesticides as their bodies are still developing. Furthermore, a\u00a0mother\u2019s exposure<\/a>\u00a0to environmental toxicants while pregnant may increase the likelihood of developing brain malformations as most developmental disabilities begin\u00a0before birth<\/a>. A plethora of studies not only link\u00a0childhood<\/a>\u00a0pesticide exposure, but\u00a0prenatal<\/a>\u00a0pesticide exposure, as well, to brain tumor development. The number of children with neurodevelopmental disabilities is\u00a0increasing<\/a>\u00a0in the U.S., and many children in rural areas\u2014where pesticide use is most prevalent\u2014have a higher rate of neurological disabilities. Children\u00a0living on or in proximity<\/a>\u00a0to farms are more likely to encounter these toxic chemicals from performing farm-related activities (i.e., storing\/handling pesticides, fieldwork) or leisure activities around farms (i.e., swimming in nearby contaminated water, eating crops from the field). Pesticides can have various impacts on cognitive function that are not easily classifiable with exposure-response. Headaches are the most common symptom of pesticide applications, but exposure can have confounding impacts on human health as\u00a0headaches often accompany<\/a>\u00a0other pesticide poising symptoms. Therefore, it is essential to effectively monitor and assess pesticide exposure for the sake of human health.<\/p>\n

The study results find an increased risk for brain cancer among those working with livestock. Many pesticides used on livestock are insecticides that specifically impact the nervous system of invertebrates. However, many\u00a0studies<\/a>\u00a0demonstrate that exposure to pesticides, such as organophosphate insecticides, like chlorpyrifos, have endocrine disruption properties that induce neurotoxicity via\u00a0acetylcholinesterase (AChE) inhibition<\/a>. A\u00a02015<\/a>\u00a0Harvard University meta-analysis found that indoor use of insecticides was associated with a 47 percent increase in childhood leukemia and a 43 percent increase in childhood lymphoma. However, various herbicides, including\u00a0paraquat<\/a>, have links to neurotoxic impacts like Parkinson\u2019s disease and loss of senses (i.e., hearing, smell, sight). Furthermore, a\u00a02008 study<\/a>\u00a0found that women who reported using herbicides have a more than doubled risk for meningioma brain cancer compared with women who never use herbicides. The brain cancer risk increases significantly with increasing years of cumulative herbicide exposure. A majority of exposure comes from handling herbicide-contaminated produce in grocery stores\/restaurants, rather than direct pesticide application.<\/p>\n

This study adds to the growing\u00a0body of research<\/a>\u00a0supporting a link between neurological problems and individuals with frequent exposure to pesticides. The journal\u00a0Occupational and Environmental Medicine\u00a0<\/em><\/a>indicates that farmworkers and persons exposed to high levels of pesticides have an increased risk of developing brain tumors, especially gliomas \u2013 a tumor of the nervous system. Furthermore, this study confirms previous studies<\/a>\u00a0 that find farmworkers experience higher rates of specific cancers, like brain cancer. Farmworkers are at the greatest risk of pesticide-induced disease and their average life expectancy bears this out. According to the\u00a0National Farm Worker Ministry<\/a>, farmworkers have an average life span of\u00a049 years<\/a>, a 29 year difference from the general U.S. population. The researchers conclude \u201c\u2026that the synthesis of evidence from over 40 years of epidemiologic literature supports an increased risk of brain cancer from farming with its potential for exposure to chemical pesticides. Increasing organic farming practices is one means to reduce the exposure of farmers to chemical pesticides.\u201d<\/p>\n

Globally,\u00a0cancer<\/a>\u00a0is one of the leading causes of death, with over eight million people succumbing to the disease every year. Notably,\u00a0the International Agency for Research on Cancer<\/a>\u00a0(IARC) predicts an increase in new cancer cases to increase from 19.3 million to 30.2 million per year by 2040.\u00a0Several studies<\/a>\u00a0link pesticide use and residue to various cancers, from more prevalent forms, like\u00a0breast cancer<\/a>, to rare forms like\u00a0kidney cancer nephroblastoma<\/a>\u00a0<\/em>(Wilms\u2019 tumor). Therefore, studies related to pesticides and cancer will aid in future understand of the underlying mechanisms that cause the disease.<\/p>\n

It is essential to understand the health implications of pesticide use and exposure on humans, especially if pesticides increase chronic disease risk. Beyond Pesticides tracks the most recent news and studies related to pesticides through the\u00a0Daily News Blog<\/a>\u00a0and\u00a0Pesticide-Induced Diseases Database (PIDD)<\/a>. This database supports the clear need for strategic action to shift away from pesticide dependency. For more information on the adverse effects of pesticides on human health, see PIDD pages on\u00a0cancer<\/a>\u00a0(including\u00a0brain<\/a>\u00a0cancer),\u00a0brain and nervous system disorders<\/a>,\u00a0endocrine disruption<\/a>, and other diseases. Furthermore, to learn more about farmworker protection, please visit Beyond Pesticide\u2019s\u00a0Agricultural Justice<\/a>\u00a0page.<\/p>\n

All unattributed positions and opinions in this piece are those of Beyond Pesticides.<\/em><\/p>\n

Source: Claremont Graduate University<\/a>\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"

(Beyond Pesticides, September 23, 2021) A study by\u00a0Claremont Graduate University finds exposure to agricultural pesticides increases brain cancer risk up to 20 percent. This study expands on a 1998 study evaluating brain cancer risk among the farm population using epidemiologic studies. The etiology (cause) of brain cancer is inconclusive for many forms, including glioma and meningioma. Brain cancer risk factors include family history and exposure to radiation. However, geographical variance in brain cancer incidents suggests environmental pollutants like pesticides contribute to risk. Various\u00a0research studies\u00a0already note the adverse effects pesticide exposure has on the brain. These effects range from headaches and tumors to learning and developmental disabilities among children and adults. Although general cancer incidents are decreasing, brain and nervous system cancers are rising. Therefore, studies like this highlight the need to reevaluate pesticide exposure limits for those working with or around agricultural chemicals to prevent chronic, deadly diseases. The study researchers note, \u201cThis comprehensive review and meta-analysis encompassing 42 years of the epidemiologic literature and updating two previous meta-analyses by 20 years supports an association between farming and brain cancer incidence and mortality.[…]Our analyses suggest that the elevated risk has been consistent over time, and the addition of newer studies […]<\/p>\n","protected":false},"author":2,"featured_media":29918,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[400,196,21,215],"tags":[],"class_list":["post-29916","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-brain-effects","category-cancer","category-chemicals","category-farmworkers"],"yoast_head":"\nStudy Adds to 40 Year Analysis Linking Brain Cancer to Pesticide Exposure - Beyond Pesticides Daily News Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study Adds to 40 Year Analysis Linking Brain Cancer to Pesticide Exposure - Beyond Pesticides Daily News Blog\" \/>\n<meta property=\"og:description\" content=\"(Beyond Pesticides, September 23, 2021) A study by\u00a0Claremont Graduate University finds exposure to agricultural pesticides increases brain cancer risk up to 20 percent. 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The study researchers note, \u201cThis comprehensive review and meta-analysis encompassing 42 years of the epidemiologic literature and updating two previous meta-analyses by 20 years supports an association between farming and brain cancer incidence and mortality.[…]Our analyses suggest that the elevated risk has been consistent over time, and the addition of newer studies […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/\" \/>\n<meta property=\"og:site_name\" content=\"Beyond Pesticides Daily News Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/beyondpesticides\" \/>\n<meta property=\"article:author\" content=\"https:\/\/www.facebook.com\/beyondpesticides\/\" \/>\n<meta property=\"article:published_time\" content=\"2021-09-23T04:01:37+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2021\/09\/brain.png\" \/>\n\t<meta property=\"og:image:width\" content=\"640\" \/>\n\t<meta property=\"og:image:height\" content=\"320\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Beyond Pesticides\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@ByondPesticides\" \/>\n<meta name=\"twitter:site\" content=\"@ByondPesticides\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Beyond Pesticides\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/\"},\"author\":{\"name\":\"Beyond Pesticides\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/person\/1b5c0a0981b549cc5b628770073031f4\"},\"headline\":\"Study Adds to 40 Year Analysis Linking Brain Cancer to Pesticide Exposure\",\"datePublished\":\"2021-09-23T04:01:37+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/\"},\"wordCount\":1337,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#organization\"},\"image\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2021\/09\/brain.png\",\"articleSection\":[\"Brain Effects\",\"Cancer\",\"Chemicals\",\"Farmworkers\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/\",\"url\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/\",\"name\":\"Study Adds to 40 Year Analysis Linking Brain Cancer to Pesticide Exposure - 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This study expands on a 1998 study evaluating brain cancer risk among the farm population using epidemiologic studies. The etiology (cause) of brain cancer is inconclusive for many forms, including glioma and meningioma. Brain cancer risk factors include family history and exposure to radiation. However, geographical variance in brain cancer incidents suggests environmental pollutants like pesticides contribute to risk. Various\u00a0research studies\u00a0already note the adverse effects pesticide exposure has on the brain. These effects range from headaches and tumors to learning and developmental disabilities among children and adults. Although general cancer incidents are decreasing, brain and nervous system cancers are rising. Therefore, studies like this highlight the need to reevaluate pesticide exposure limits for those working with or around agricultural chemicals to prevent chronic, deadly diseases. The study researchers note, \u201cThis comprehensive review and meta-analysis encompassing 42 years of the epidemiologic literature and updating two previous meta-analyses by 20 years supports an association between farming and brain cancer incidence and mortality.[…]Our analyses suggest that the elevated risk has been consistent over time, and the addition of newer studies […]","og_url":"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/","og_site_name":"Beyond Pesticides Daily News Blog","article_publisher":"https:\/\/www.facebook.com\/beyondpesticides","article_author":"https:\/\/www.facebook.com\/beyondpesticides\/","article_published_time":"2021-09-23T04:01:37+00:00","og_image":[{"width":640,"height":320,"url":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2021\/09\/brain.png","type":"image\/png"}],"author":"Beyond Pesticides","twitter_card":"summary_large_image","twitter_creator":"@ByondPesticides","twitter_site":"@ByondPesticides","twitter_misc":{"Written by":"Beyond Pesticides","Est. reading time":"7 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/#article","isPartOf":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/"},"author":{"name":"Beyond Pesticides","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/person\/1b5c0a0981b549cc5b628770073031f4"},"headline":"Study Adds to 40 Year Analysis Linking Brain Cancer to Pesticide Exposure","datePublished":"2021-09-23T04:01:37+00:00","mainEntityOfPage":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/"},"wordCount":1337,"commentCount":0,"publisher":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#organization"},"image":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/#primaryimage"},"thumbnailUrl":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2021\/09\/brain.png","articleSection":["Brain Effects","Cancer","Chemicals","Farmworkers"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/","url":"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/09\/study-adds-to-40-year-analysis-linking-brain-cancer-to-pesticide-exposure\/","name":"Study Adds to 40 Year Analysis Linking Brain Cancer to Pesticide Exposure - 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By forging ties with governments, nonprofits, and people who rely on these natural resources, we reduce the need for unnecessary pesticide use and protect public health and the environment. Beyond Pesticides provides hands-on services to the public and supports local action by: identifying and interpreting hazards; and, designing safe pest management programs. With the information provided by Beyond Pesticides, people may not only be able to make informed choices and adopt practices that protect themselves and their families from unnecessary exposure to pesticides, but they will be able to effect changes on community-wide pest management decisions and policies that govern pesticide use, such as pesticide uses in parks, schools, for community insect control and along roadsides. 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