{"id":37505,"date":"2025-01-28T00:01:03","date_gmt":"2025-01-28T05:01:03","guid":{"rendered":"https:\/\/beyondpesticides.org\/dailynewsblog\/?p=37505"},"modified":"2025-01-29T13:53:37","modified_gmt":"2025-01-29T18:53:37","slug":"beyond-pesticides-calls-on-epa-to-ensure-comprehensive-review-of-biopesticides","status":"publish","type":"post","link":"https:\/\/beyondpesticides.org\/dailynewsblog\/2025\/01\/beyond-pesticides-calls-on-epa-to-ensure-comprehensive-review-of-biopesticides\/","title":{"rendered":"Beyond Pesticides Calls on EPA To Ensure Comprehensive Review of \u201cBiopesticides\u201d"},"content":{"rendered":"\r\n<p>(Beyond Pesticides, January 28, 2025) Beyond Pesticides is urging the U.S. Environmental Protection Agency (EPA) to move more cautiously in \u00a0<a href=\"https:\/\/www.epa.gov\/pesticides\/epa-proposes-streamlined-registration-review-process-several-low-risk-biopesticides\">its proposal<\/a>\u00a0for \u201cstreamlined . . . registration review decisions for several biopesticides,\u201d subject to a public comment period through February 10, 2025. The organization is raising EPA review process concerns. The organization states: \u201cAlthough the biopesticides listed in EPA&#8217;s proposal for streamlining the registration review process for \u2018low risk biopesticides\u2019 can be considered relatively low risk compared to conventional pesticides, the precedent for relying on the original or previous registration data and review is troublesome. EPA&#8217;s rationale for registration review\u2014that \u2018science is constantly evolving, and new scientific information can come to light at any time and change our understanding of potential effects from pesticides,\u2019 should guide the agency in its decisions\u2014especially when previous decisions have depended on limited actual data, data waiver request rationales, and purported absence of new data or adverse incidents reported.\u201d\u00a0<\/p>\r\n<p>While Beyond Pesticides advocates for allowance of pesticides compatible with organic standards that are protective of human health, biodiversity, and healthy ecosystems, it urges EPA to establish rigorous standards in its registration review of these materials. The issue of biopesticide review is made complicated by the broad definition that the agency uses for the term. EPA uses the following definition for \u201cbiopesticides\u201d:<\/p>\r\n<ul>\r\n\t<li>Substances that interfere with mating, such as insect sex pheromones, as well as various scented plant extracts that attract insect pests to traps (and synthetic analogs of such biochemicals);<\/li>\r\n\t<li>Microbial pesticides consisting of a microorganism (e.g., a bacterium, fungus, virus or protozoan) as the active ingredient;<\/li>\r\n\t<li>Plant-Incorporated-Protectants (PIPs), pesticidal substances that plants are genetically engineered to produce.<\/li>\r\n<\/ul>\r\n<p>In the context, the mechanisms at work and the biological and chemical effects, while viewed as important alternatives to petrochemical pesticides, require careful evaluation, according to the Beyond Pesticides comments. Additionally, Beyond Pesticides has urged EPA to drop PIPs from its definition of biopesticides because of widespread insect resistance to valuable ecologically based materials and indiscriminate disruption of the ecosystem. (See <a href=\"https:\/\/secure.everyaction.com\/Tsca3jfy10GajLUgv5AZFw2?emci=3658ef32-4d01-ec11-b563-501ac57b8fa7&amp;emdi=ea000000-0000-0000-0000-000000000001&amp;ceid=\">Tell EPA that Biopesticides Must Be Redefined<\/a>.) Furthermore, it is Beyond Pesticides\u2019 position, also incorporated into the\u00a0<a href=\"https:\/\/www.ams.usda.gov\/sites\/default\/files\/media\/Organic%20Foods%20Production%20Act%20of%201990%20(OFPA).pdf\">Organic Foods Production Act (OFPA)<\/a>, that any pest management inputs used in ecological-based farming systems (e.g., organic farming) must be only one part of an organic systems plan that focuses primarily on building soil health and enhancing biodiversity, (often referred to as ecosystems services), foundational to plant health, resilience, and prevention of disease and infestations. However, biopesticides are often discussed in the scientific literature as a substitution for synthetic petrochemical pesticides or to be used alongside synthetic chemical controls in an <a href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2021\/10\/ipm-integrated-pest-management-fails-to-stop-toxic-pesticide-use\/\">Integrated Pesticide Management (IPM<\/a>) system. (See \u201c<a href=\"https:\/\/www.frontiersin.org\/journals\/microbiology\/articles\/10.3389\/fmicb.2023.1040901\/full\">Biopesticides as a promising alternative to synthetic pesticides: A case for microbial pesticides, phytopesticides, and nanobiopesticides.<\/a>\u201d) Organic advocates maintain that without a holistic approach, land managers remain on a pesticide treadmill and undercut ecological balance necessary in organic systems.<\/p>\r\n<p>Because EPA considers the four \u201cbiopesticides\u201d in its proposal to be \u201clow risk,\u201d \u201c[t]he Agency is proposing that no further registration review is necessary for these biopesticides at this time.\u201d Although the biopesticides listed in EPA&#8217;s proposal for streamlining the registration review process for &#8220;low risk biopesticides&#8221; can be considered relatively low risk compared to conventional pesticides, the precedent for relying on the original or previous registration data and review is troublesome.<\/p>\r\n<p><strong><a href=\"https:\/\/secure.everyaction.com\/wptudJnMl0e5Ql88qSfCsQ2##anchor\">&gt;&gt; Tell EPA to do full registration reviews for all pesticides.<\/a>\u00a0<\/strong><\/p>\r\n<p>The\u00a0<a href=\"https:\/\/www.epa.gov\/sites\/default\/files\/documents\/fifra.pdf\"><em>Federal Insecticide, Fungicide, and Rodenticide Act<\/em><\/a>\u00a0(FIFRA) requires that the Environmental Protection Agency (EPA) conduct a\u00a0<a href=\"https:\/\/www.epa.gov\/pesticide-reevaluation\/registration-review-process\">registration review\u00a0<\/a>of all registered pesticides every 15 years. EPA\u00a0<a href=\"https:\/\/www.epa.gov\/pesticide-reevaluation\/registration-review-process\">explains<\/a>, \u201c[S]cience is constantly evolving, and new scientific information can come to light at any time and change our understanding of potential effects from pesticides.\u201d<\/p>\r\n<p>The four biopesticides to which this proposal pertains are alpha methyl mannoside (a plant growth regulator to improve the growth of a range of crops);\u00a0<em>Duddingtonia flagrans<\/em>\u00a0strain IAH 1297 (to break the cycle of parasitic nematode infections in grazing animals); Pepino mosaic virus, strain CH2, isolate 1906 (to protect greenhouse tomatoes from other viruses); and sheep fat (to repel animals like deer from ornamentals, trees, shrubs, and other plants).\u00a0<strong>When considering the listed biopesticides in the proposal, EPA&#8217;s summaries are predominantly dependent on limited actual data, data waiver request rationales, and purported absence of new data or adverse incidents reported. The absence of adverse effect evidence is not evidence of no adverse effects.<\/strong><\/p>\r\n<p>For alpha methyl mannoside, all human health data requirements were satisfied by a combination of data, waiver rationales, and the bridging of information from guar gum where high concentrations of mannose polymers are present. For ecological effects, all nontarget toxicology data requirements have been satisfied through guideline studies that demonstrated low acute toxicity for birds, mammals, aquatic organisms, invertebrates, and plants. EPA has concluded that adverse effects are not anticipated to birds, mammals, freshwater fish, aquatic invertebrates, insects, and nontarget plants. Curiously, the agency also determined that effects to federally listed threatened and endangered species and their designated critical habitats are not expected from these uses. However, the mode of action for alpha methyl mannoside, as a plant growth regulator, is to stimulate growth of treated plants. It is unclear why stimulating the growth of listed plant species, if exposed, or plants in the critical habitat of a listed species either plant or animal, if exposed, would not be potentially problematic or negatively affected by excessive growth. This seems worthy of more in-depth consideration as many herbicides function by excessive growth stimulation of target weeds, which can pose serious risks to nontarget plants.<\/p>\r\n<p>For\u00a0<em>Duddingtonia flagrans<\/em>\u00a0strain IAH 1297, the registrant requested consideration of the history of safe use, the global ubiquity of\u00a0<em>D. flagrans<\/em>, and the rationale based on literature sources to satisfy the data requirements for avian toxicity, wild mammal toxicity, aquatic organism testing, nontarget plant testing, and nontarget insect testing. EPA accepted the data waiver requests.<\/p>\r\n<p>Similarly for Pepino mosaic virus, strain CH2, isolate 1906, scientific rationale was submitted and accepted to satisfy data requirements for Avian oral, Avian inhalation, Wild mammals, Freshwater fish, Freshwater invertebrates, Estuarine\/marine fish and invertebrates, Nontarget insects, Honey bees, and Nontarget Plant toxicity\/pathogenicity testing. Additionally, some nontarget plant testing, persistence in soil, persistence in water, algal toxicity, duckweed growth inhibition, and vegetative vigor studies were submitted. The results from the nontarget plant testing study are considered supplemental due to several deficiencies in the study, and it is not robust enough to conclude a lack of hazard for nontarget plants. The aquatic plant studies did not adequately describe the positive controls used, why the virus was not detectable at the start of the experiments, and did not describe the concentration (lg\/L) of Pepino mosaic virus, strain CH2, isolate 1906 treatment in the Algal toxicity test which may have caused minimal growth inhibition.<\/p>\r\n<p>EPA distinguishes three classes of biopesticides\u2014biochemical, microbial, and plant-incorporated protectants (PIPs). The agency says, \u201cBecause it is sometimes difficult to determine whether a substance meets the criteria for classification as a biochemical pesticide, EPA has established a special committee to make such decisions.\u201d \u201cBiopesticides\u201d are often assumed to be safer than \u201cconventional\u201d pesticides because they are assumed to be \u201cnatural.\u201d However, EPA&#8217;s definition of biopesticides\u2014&#8221;derived from such natural materials as animals, plants, bacteria, and certain minerals\u201d\u2014does not mean that they are \u201cnatural.\u201d Many of them would not qualify as \u201cnonsynthetic\u201d inputs in organic farming because the organic law requires consideration of manufacturing processes. Since some biopesticides\u2014for example, pheromones\u2014occur in minute quantities naturally, they are produced through chemical synthesis for commercial use. Such synthetic chemicals must be recommended by the\u00a0<a href=\"https:\/\/www.ams.usda.gov\/rules-regulations\/organic\/nosb\">National Organic Standards Board<\/a>\u00a0before they can be used in organic production and processing. Some microbial pesticides and PIPs would not be allowed because they result from genetic engineering.<\/p>\r\n<p><strong><a href=\"https:\/\/secure.everyaction.com\/wptudJnMl0e5Ql88qSfCsQ2##anchor\">&gt;&gt; Tell EPA to do full registration reviews for all pesticides<\/a><a href=\"https:\/\/secure.everyaction.com\/wptudJnMl0e5Ql88qSfCsQ2##anchor\"><em>.<\/em><\/a><em>\u00a0<\/em><\/strong><\/p>\r\n<p><u>Suggested comment to EPA:<br \/>\r\n<\/u>Although biopesticides in the proposal for streamlining the registration review process for &#8220;low risk biopesticides&#8221; can be considered low risk compared to conventional pesticides, the precedent for relying on the original or previous registration data and review is unacceptable.<\/p>\r\n<p>The Federal Insecticide, Fungicide, and Rodenticide Act requires that EPA conduct a registration review of all registered pesticides every 15 years. EPA states, \u201c[S]cience is constantly evolving, and new scientific information can come to light at any time and change our understanding of potential effects from pesticides.\u201d<\/p>\r\n<p>EPA\u2019s summaries concerning Alpha methyl mannoside; <em>Duddingtonia flagrans<\/em> strain IAH 1297; Pepino mosaic virus, strain CH2, isolate 1906; and\u00a0sheep fat are predominantly dependent on limited actual data, data waiver request rationales, and purported absence of new data or reported adverse incidents. Absence of adverse effect evidence is not evidence of no adverse effects.<\/p>\r\n<p>All human health data requirements for alpha methyl mannoside were satisfied by a combination of data, waiver rationales, and data from guar gum where high concentrations of mannose polymers are present. EPA concluded from guideline studies that adverse effects are not anticipated to birds, mammals, freshwater fish, aquatic invertebrates, insects, and nontarget plants. Although the agency also determined that effects to federally listed threatened and endangered species and their designated critical habitats are not expected from these uses, the mode of action as a plant growth regulator is to stimulate growth of treated plants. It is unclear why stimulating growth of listed plant species or plants in a critical habitat of a listed species, either plant or animal, would not result in negative impacts. This seems worthy of more in-depth consideration, as many herbicides function by excessive growth stimulation of target weeds, posing serious risks to nontarget plants.<\/p>\r\n<p>For <em>Duddingtonia flagrans<\/em> strain IAH 1297, the registrant requested consideration of the history of safe use, the global ubiquity of <em>D. flagrans, <\/em>and a rationale based on literature sources to satisfy the data requirements for avian toxicity, wild mammal toxicity, aquatic organism testing, nontarget plant testing, and nontarget insect testing. EPA accepted the data waiver requests.<\/p>\r\n<p>Similarly for Pepino mosaic virus, strain CH2, isolate 1906, scientific rationale was accepted to satisfy data requirements for avian oral, avian inhalation, wild mammals, freshwater fish, freshwater invertebrates, estuarine\/marine fish and invertebrates, nontarget insects, honey bees, and nontarget plant toxicity\/pathogenicity testing. Some nontarget plant testing, persistence in soil, persistence in water, algal toxicity, duckweed growth inhibition, and vegetative vigor studies were submitted. The nontarget plant testing study has several deficiencies and is insufficient to support a lack of hazard for nontarget plants. The aquatic plant studies did not adequately describe the positive controls used, why the virus was not detectable at the start of the experiments, and did not describe the concentration of the treatment in the algal toxicity test which may have caused minimal growth inhibition.<\/p>\r\n<p>The EFSA 2021 peer review of the sheep fat risk assessment found toxicity data were not available for any group of nontarget organisms. A low acute and chronic risk to birds and mammals was presumed. Toxicity data to assess the chronic risk to aquatic organisms was deemed unnecessary.<\/p>\r\n<p>Although these biopesticides may be considered low risk compared to conventional pesticides, relying on the original or previous registration data and review is problematic.<\/p>\r\n<p>Thank you.<\/p>\r\n<p><em>The target\u00a0for this Action is\u00a0the U.S. Environmental Protection Agency, via comments through\u00a0<a href=\"https:\/\/www.regulations.gov\/document\/EPA-HQ-OPP-2024-0520-0001\">Regulations.gov<\/a>.<\/em><\/p>\r\n<p><em>All unattributed positions and opinions in this piece are those of Beyond Pesticides.<\/em><\/p>\r\n","protected":false},"excerpt":{"rendered":"<p>(Beyond Pesticides, January 28, 2025) Beyond Pesticides is urging the U.S. Environmental Protection Agency (EPA) to move more cautiously in \u00a0its proposal\u00a0for \u201cstreamlined . . . registration review decisions for several biopesticides,\u201d subject to a public comment period through February 10, 2025. The organization is raising EPA review process concerns. The organization states: \u201cAlthough the biopesticides listed in EPA&#8217;s proposal for streamlining the registration review process for \u2018low risk biopesticides\u2019 can be considered relatively low risk compared to conventional pesticides, the precedent for relying on the original or previous registration data and review is troublesome. EPA&#8217;s rationale for registration review\u2014that \u2018science is constantly evolving, and new scientific information can come to light at any time and change our understanding of potential effects from pesticides,\u2019 should guide the agency in its decisions\u2014especially when previous decisions have depended on limited actual data, data waiver request rationales, and purported absence of new data or adverse incidents reported.\u201d\u00a0 While Beyond Pesticides advocates for allowance of pesticides compatible with organic standards that are protective of human health, biodiversity, and healthy ecosystems, it urges EPA to establish rigorous standards in its registration review of these materials. The issue of biopesticide review is made complicated by the [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":37558,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[249,2,352,337,354,317,10,276,1],"tags":[],"class_list":["post-37505","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-agriculture","category-alternativesorganics","category-biodiversity","category-biological-control","category-environmental-protection-agency-epa","category-integrated-and-organic-pest-management","category-pesticide-regulation","category-take-action","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Beyond Pesticides Calls on EPA To Ensure Comprehensive Review of \u201cBiopesticides\u201d - Beyond Pesticides Daily News Blog<\/title>\n<meta name=\"description\" content=\"Beyond Pesticides is urging the U.S. Environmental Protection Agency to move more cautiously in\u00a0its proposal\u00a0for biopesticide registration review.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2025\/01\/beyond-pesticides-calls-on-epa-to-ensure-comprehensive-review-of-biopesticides\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Beyond Pesticides Calls on EPA To Ensure Comprehensive Review of \u201cBiopesticides\u201d - 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