{"id":40450,"date":"2025-12-04T00:01:22","date_gmt":"2025-12-04T05:01:22","guid":{"rendered":"https:\/\/beyondpesticides.org\/dailynewsblog\/?p=40450"},"modified":"2025-12-04T11:14:51","modified_gmt":"2025-12-04T16:14:51","slug":"at-odds-with-int-regulatory-bodies-epa-defines-away-pfas-problem-allows-widespread-contamination","status":"publish","type":"post","link":"https:\/\/beyondpesticides.org\/dailynewsblog\/2025\/12\/at-odds-with-int-regulatory-bodies-epa-defines-away-pfas-problem-allows-widespread-contamination\/","title":{"rendered":"At Odds with Intl Regulatory Bodies, EPA Defines Away PFAS Problem, Allows Widespread Contamination"},"content":{"rendered":"<p><span data-contrast=\"none\">(<\/span><i><span data-contrast=\"none\">Beyond Pesticides<\/span><\/i><span data-contrast=\"none\">, December\u00a04, 2025)\u00a0In a\u00a0<\/span><a href=\"https:\/\/www.epa.gov\/newsreleases\/fact-check-epa-debunks-false-claims-agency-recently-approved-forever-chemical\"><span data-contrast=\"none\">news\u00a0release<\/span><\/a><span data-contrast=\"none\">\u00a0last week\u00a0on November 26, 2025,\u00a0the U.S. Environmental Protection Agency (EPA) \u201cissued a comprehensive fact-check addressing dangerous misinformation circulating about EPA&#8217;s recent pesticide approvals\u201d that, according to health and\u00a0environmental advocates,\u00a0continues to deceive the public about the true risks for health and the environment from petrochemical pesticides including, but not limited to,\u00a0per- and polyfluoroalkyl substances (PFAS).\u00a0Also published on November 26, coverage titled\u00a0<\/span><a href=\"https:\/\/time.com\/7336883\/epa-pfas-pesticides-health-risks\/\"><span data-contrast=\"none\">The EPA Is Embracing PFAS Pesticides. These Are The Health Risks<\/span><\/a><span data-contrast=\"none\">\u00a0in\u00a0<\/span><i><span data-contrast=\"none\">Time<\/span><\/i><span data-contrast=\"none\">\u00a0further highlights EPA\u2019s deficiencies and the threats of PFAS, which Beyond Pesticides has extensively covered. (See\u00a0<\/span><a href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/category\/environmental-protection-agency-epa\/\"><span data-contrast=\"none\">here<\/span><\/a><span data-contrast=\"none\">\u00a0and\u00a0<\/span><a href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/category\/chemicals\/pfas\/\"><span data-contrast=\"none\">here<\/span><\/a><span data-contrast=\"none\">.)<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p>The controversy erupted as a result of EPA\u2019s latest proposal to allow a new fluorinated pesticide to the list of four other similar compounds now widely available for use in homes and gardens, buildings, and agriculture. The newest pesticide proposed for EPA registration, <a href=\"https:\/\/www.beyondpesticides.org\/assets\/media\/documents\/BP%20Comments%20on%20Epyrifenacil%2012.3.25.pdf\">epyrifenacil <\/a>(agricultural weed killer), joins <a href=\"http:\/\/www.bp-dc.org\/bp-comments-on-cyclobutrifluram-may-2025\">cyclobutrifluram<\/a> (soil fungicide\/nematicide), <a href=\"http:\/\/www.bp-dc.org\/bp-comments-on-isocycloseram-june-2025\">isocycloseram<\/a> (household and agricultural insecticide), <a href=\"http:\/\/bp-dc.org\/bp-comments-on-diflufenican-july-2025\">diflufenican<\/a> (lawn and agricultural weed killer), and <a href=\"https:\/\/bp-dc.org\/bp-comments-on-trifludimoxazin-july-2025\">trifludimoxazin<\/a> (agricultural weed killer), making a total of five PFAS pesticide proposals this year that have been associated with national and worldwide contamination of food, land, and water. Two of these, cyclobutrifluram and isocycloseram, have been approved.<\/p>\n<p><span data-contrast=\"none\">\u201cInstead of constraining the use of fluorinated pesticides\u2014persistent and highly toxic compounds defined as PFAS internationally\u2014EPA is opening the door to further threats to health with generational harm,\u201d said Jay Feldman, executive director of Beyond Pesticides. \u201cThe agency is allowing public and worker exposure and environmental contamination of food and water to chemical compounds that cause <\/span><span data-contrast=\"auto\">hormonal disruptions, developmental issues, and cancer, despite the\u00a0availability of\u00a0productive and profitable alternative practices and\u00a0nontoxic\u00a0products,\u201d he said.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">While EPA is politicizing a serious public health and environmental issue, with EPA Administrator Lee Zeldin calling news reports on PFAS pesticides \u201cfake news from Democrats and their media allies,&#8221; at the root of the issue is the classification of fluorinated chemical compounds <\/span><span data-contrast=\"none\">(containing the element fluorine)\u00a0<\/span><span data-contrast=\"auto\">that put the agency at odds with international regulatory bodies. Beyond the classification of the compounds\u00a0are issues of hazards to health and the environment, given the scientific findings tying the chemical to\u00a0highly\u00a0threatening adverse effects.<\/span><em> See a press release by Beyond Pesticides <a href=\"https:\/\/www.bp-dc.org\/epa-pfas-pr-12.3.25\">here<\/a>.<\/em><\/p>\n<p><span data-contrast=\"none\">In a news release, EPA says, \u201cE]<\/span><span data-contrast=\"auto\">very\u00a0approved pesticide undergoes thorough safety evaluation and poses no health risks when used as directed.\u00a0BOTTOM LINE: EPA-Approved Single Fluorinated Compounds Are NOT Forever Chemicals and Pose No Safety Concerns When Used According to Label Instructions.\u201d<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"none\">When a\u00a0Chemical\u00a0is\u00a0Classified\u00a0as PFAS\u00a0<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">In its argument, EPA is ignoring the widely accepted definition of PFAS, supported by scientists, through the Organization for Economic Cooperation and Development (OECD). As previously covered by Beyond Pesticides in <\/span><i><span data-contrast=\"none\">Daily News<\/span><\/i><span data-contrast=\"none\">, titled\u00a0<\/span><a href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2025\/07\/artificially-narrow-epa-definition-of-pfas-mischaracterizes-widespread-threat-to-health-and-environment\/\"><span data-contrast=\"none\">Artificially Narrow EPA Definition of PFAS Mischaracterizes Widespread Threat to Health and Environment<\/span><\/a><span data-contrast=\"none\">, the definition of PFAS, also known as \u201cforever chemicals\u201d due to their persistence, continues to be debated in\u00a0the\u00a0regulatory\u00a0arena, with many scientists arguing that certain types of chemicals in this vast group are not accurately captured in\u00a0EPA\u00a0risk assessments.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">The definition of PFAS used by OECD encompasses a wide variety of fluorinated compounds and is \u201cscientifically grounded, unambiguous, and well suited to identify these chemicals,\u201d as described by scientists in a commentary published in\u00a0<\/span><a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.estlett.5c00478\"><i><span data-contrast=\"none\">Environmental Science &amp; Technology Letters<\/span><\/i><\/a><span data-contrast=\"none\">. As the researchers describe, excluding certain fluorinated chemical subgroups does not\u00a0properly represent\u00a0the scope of PFAS, which they estimate to include millions of theoretical structures, but\u00a0more practically,\u00a0several\u00a0thousand that are\u00a0actually manufactured.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">The\u00a0<\/span><a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.1c06896\"><span data-contrast=\"none\">OECD chemical definition<\/span><\/a><span data-contrast=\"none\">\u00a0of PFAS states:<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span data-contrast=\"none\">PFASs are defined as fluorinated substances that contain at least one fully fluorinated methyl or methylene carbon atom (without any H\/Cl\/Br\/I atom attached to it), i.e., with a few noted exceptions, any chemical with at least a perfluorinated methyl group (\u2212CF3) or a perfluorinated methylene group (\u2212CF2\u2212) is a PFAS.<\/span><span data-ccp-props=\"{&quot;335559685&quot;:720}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">This definition of PFAS encompasses gases, pesticides, and pharmaceuticals,\u00a0many\u00a0of which can degrade to form\u00a0additional\u00a0PFAS, such as trifluoroacetic acid (TFA), that regulatory bodies like EPA do not include in their definitions.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">As the<\/span><i><span data-contrast=\"auto\">\u00a0<\/span><\/i><a href=\"https:\/\/time.com\/7336883\/epa-pfas-pesticides-health-risks\/\"><i><span data-contrast=\"none\">Time<\/span><\/i><\/a><span data-contrast=\"auto\">\u00a0article points out: \u201c[T]here is no firm definition of exactly what a PFAS is\u2014at least in the United States. The Paris-based Organization for Economic Cooperation and Development (OECD), which works with 38 member nations including the U.S. to foster international cooperation and economic growth, defines PFAS as industrial chemicals that have at least one fully fluorinated carbon atom\u2014which is a carbon atom with two or three fluorine atoms attached to it. There are about 15,000 species of chemicals that meet that standard. But the EPA has pushed back, broadening the\u00a0definition to two fully fluorinated carbon atoms.\u201d<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">EPA\u00a0is pointing to\u00a0the Biden administration for approving\u00a0the single fluorinated compound\u00a0<\/span><a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Fluazaindolizine\"><span data-contrast=\"none\">fluazaindolizine<\/span><\/a><span data-contrast=\"auto\">\u00a0with a clear signal\u00a0that single fluorinated compounds are not PFAS.\u00a0The Trump Administration, however, has already doubled that approval rate, allowing the registration of\u00a0cyclobutrifluram\u00a0and\u00a0isocycloseram\u00a0within the\u00a0term\u2019s\u00a0first year\u00a0and within two weeks of each other. Three other PFAS have\u00a0been proposed\u00a0by EPA, which could bring the total approved\u00a0PFAS\u00a0active ingredients\u00a0to five within\u00a0a short time\u00a0frame. Beyond Pesticides\u00a0submitted\u00a0comments on the proposals of\u00a0<\/span><a href=\"http:\/\/www.bp-dc.org\/bp-comments-on-cyclobutrifluram-may-2025\"><span data-contrast=\"none\">cyclobutrifluram<\/span><\/a><span data-contrast=\"auto\">\u00a0and\u00a0<\/span><a href=\"http:\/\/www.bp-dc.org\/bp-comments-on-isocycloseram-june-2025\"><span data-contrast=\"none\">isocycloseram<\/span><\/a><span data-contrast=\"auto\">, with 20 signatories, prior to their approval, as well as\u00a0comments on\u00a0<\/span><a href=\"http:\/\/bp-dc.org\/bp-comments-on-diflufenican-july-2025\"><span data-contrast=\"none\">diflufenican<\/span><\/a><span data-contrast=\"auto\">,\u00a0<\/span><a href=\"https:\/\/bp-dc.org\/bp-comments-on-trifludimoxazin-july-2025\"><span data-contrast=\"none\">trifludimoxazin<\/span><\/a><span data-contrast=\"auto\">, and\u00a0for\u00a0the latest\u00a0comment period for\u00a0<\/span><a href=\"http:\/\/bp-dc.org\/bp-comments-on-epyrifenacil-december-2025\"><span data-contrast=\"none\">epyrifenacil<\/span><\/a><span data-contrast=\"auto\">\u00a0just this month.\u00a0\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"auto\">Risks of PFAS Exposure<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">As referenced in the\u00a0<\/span><a href=\"https:\/\/time.com\/7336883\/epa-pfas-pesticides-health-risks\/\"><i><span data-contrast=\"none\">Time<\/span><\/i><\/a><span data-contrast=\"auto\">\u00a0article, \u201cPFAS have been\u00a0<\/span><a href=\"https:\/\/www.epa.gov\/pfas\/our-current-understanding-human-health-and-environmental-risks-pfas#:~:text=What%20We%20Know%20about%20Health,blood%20pressure%20in%20pregnant%20women\"><span data-contrast=\"none\">linked by the EPA<\/span><\/a><span data-contrast=\"auto\">\u00a0itself to an increased risk of a host of health effects, including decreased fertility, hypertension in pregnant people, increased risk of certain\u00a0<\/span><a href=\"https:\/\/www.beyondpesticides.org\/resources\/pesticide-induced-diseases-database\/cancer\"><span data-contrast=\"none\">cancers<\/span><\/a><span data-contrast=\"auto\">\u00a0(especially kidney cancer), developmental delays in children, hormonal irregularities, elevated cholesterol, reduced effectiveness of the immune system, and more.\u201d\u00a0Beyond Pesticides, in\u00a0<\/span><a href=\"http:\/\/bp-dc.org\/bp-comments-on-epyrifenacil-december-2025\"><span data-contrast=\"none\">previous comments<\/span><\/a><span data-contrast=\"auto\">\u00a0and\u00a0<\/span><a href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/category\/chemicals\/pfas\/\"><i><span data-contrast=\"none\">Daily News<\/span><\/i><span data-contrast=\"none\">\u00a0coverage<\/span><\/a><span data-contrast=\"auto\">, has also highlighted these\u00a0health threats, among others.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">From\u00a0<\/span><a href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2025\/01\/multitude-of-studies-find-epigenetic-effects-from-pfas-and-other-endocrine-disrupting-pesticides\/\"><span data-contrast=\"none\">epigenetic<\/span><\/a><span data-contrast=\"auto\">\u00a0to\u00a0<\/span><a href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2024\/07\/science-on-forever-chemicals-pfas-as-pesticide-ingredients-and-contaminants-supports-need-for-immediate-action-to-end-their-use\/\"><span data-contrast=\"none\">immunotoxic<\/span><\/a><span data-contrast=\"auto\">\u00a0effects, there is a wide range of health implications with PFAS exposure.\u00a0Because of their ubiquitous use,\u00a0<\/span><a href=\"https:\/\/www.atsdr.cdc.gov\/ToxProfiles\/tp200-c2.pdf\"><span data-contrast=\"none\">studies<\/span><\/a><span data-contrast=\"auto\">\u00a0report that PFAS compounds are detectable in infants, children, and pregnant women.\u00a0Furthermore, pregnant women can readily transfer compounds to the developing fetus through the placenta.\u00a0PFAS residues are persistent in food and drinking water, with over six million U.S. residents regularly\u00a0encountering\u00a0drinking water with\u00a0<\/span><a href=\"https:\/\/www.epa.gov\/system\/files\/documents\/2022-01\/dwtable2018.pdf\"><span data-contrast=\"none\">PFAS levels<\/span><\/a><span data-contrast=\"auto\">\u00a0above the EPA health advisory of 70 ng\/L.\u00a0Therefore, PFAS are detectable in\u00a0almost all\u00a0of the U.S. population\u2014<\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10233791\/\"><span data-contrast=\"none\">disproportionately afflicting people of color communities<\/span><\/a><span data-contrast=\"auto\">\u2014and have implications for human health.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">It is\u00a0evident\u00a0that EPA and other federal regulators have been behind the curve in preventing and responding to the threats posed by PFAS compounds. Despite evidence\u00a0on\u00a0the dangers of PFAS stretching as far back as the 1950s, federal agencies effectively sat on the sidelines as the plastics industry continued adding the material to new products. Now we are seeing\u00a0a similar\u00a0expansion of use with the registration of pesticides in the PFAS group.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The detection of any level of PFAS is cause\u00a0for\u00a0concern. As drinking water health advisories issued by EPA show,\u00a0<\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S266691102200020X\"><span data-contrast=\"none\">PFAS levels<\/span><\/a><span data-contrast=\"auto\">\u00a0as low as .02 parts per trillion (ppt) have the potential to cause adverse health effects for public health. From widespread presence in farm fields and sewage sludge (biosolids) to contaminated water bodies throughout the U.S., PFAS have made their way into the environment and human bodies. PFAS are even present in remote environments like the Arctic, Antarctica, and Eastern European Tibetan Plateau. The U.S. Centers for Disease Control and Prevention (CDC)\u00a0determined\u00a0that\u00a0almost all\u00a0Americans have some level of\u00a0<\/span><a href=\"https:\/\/www.epa.gov\/sdwa\/drinking-water-health-advisories-has\"><span data-contrast=\"none\">PFAS in their bloodstream<\/span><\/a><span data-contrast=\"auto\">, which highlights PFAS as a chronic danger to people that demands urgent regulatory action.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">In a literature review published in\u00a0<\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0147651324016919\"><i><span data-contrast=\"none\">Ecotoxicology and Environmental Safety<\/span><\/i><\/a><span data-contrast=\"auto\">\u00a0earlier this year, the authors highlight a multitude of studies on\u00a0<\/span><a href=\"https:\/\/www.beyondpesticides.org\/resources\/pesticide-induced-diseases-database\/endocrine-disruption\"><span data-contrast=\"none\">endocrine-disrupting<\/span><\/a><span data-contrast=\"auto\"> chemicals (EDCs) and endocrine-disrupting pesticides (EDPs) showing epigenetic effects from exposure, as the chemicals imitate the action of endocrine hormones and lead to gene damage and multigenerational adverse effects to health. In summarizing these results, the researchers state, \u201cAs a class of particularly representative endocrine-disrupting chemicals, the accumulation of per- and polyfluoroalkyl substances potentially leads to adverse health effects, including hormonal disruptions, developmental issues, and cancer.\u201d These effects result from complex mechanisms that are not yet fully assessed in EPA\u2019s pesticide registration process, creating a major deficiency in the regulatory review of pesticides that must be addressed before products are approved.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"auto\">EPA Deficiencies<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">In the\u00a0<\/span><a href=\"https:\/\/time.com\/7336883\/epa-pfas-pesticides-health-risks\/\"><i><span data-contrast=\"none\">Time<\/span><\/i><\/a><span data-contrast=\"none\">\u202farticle,\u00a0<\/span><span data-contrast=\"auto\">Nathan Donley, PhD,\u00a0points to the effect of\u00a0defining away\u00a0the PFAS pesticide problem. Dr. Donley,\u00a0environmental health science director at the Center for Biological Diversity,\u00a0states: \u201c[The EPA definition of PFAS\u00a0creates]\u00a0an enormous decrease in the number of chemicals that are subject to regulation as PFAS&#8230;\u00a0We&#8217;re\u00a0talking about defining away over 10,000 chemicals. The OECD definition was a definition agreed upon by scientists. Now, the EPA has\u00a0come up with\u00a0a regulatory definition\u00a0that in my opinion, ignores\u00a0the science and is more designed to make [the chemical industries\u2019] lives easier.\u201d<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">EPA\u00a0states: \u201cIn 2023, EPA&#8217;s Office of Pollution Prevention and Toxics officially defined PFAS, after conducting a comprehensive public rulemaking process, as chemicals\u00a0containing\u00a0two or more fluorinated carbons. This deliberate exclusion of single fluorinated carbons was based on extensive scientific evidence and public input\u00a0demonstrating\u00a0that molecules with only one fluorinated carbon lack the persistence and bioaccumulation properties that are commonly associated with forever chemicals. The recent false claims that EPA approved a\u00a0\u2018forever chemical\u2019\u00a0represents\u00a0a fundamental misunderstanding of chemistry and toxicology.\u201d\u00a0\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"none\">Fluorinated Pesticides\u00a0in General\u00a0Threaten Health<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">In\u00a0its\u00a0news release, EPA\u2019s resource on\u00a0<\/span><a href=\"https:\/\/www.epa.gov\/ingredients-used-pesticide-products\/pesticides-containing-single-fluorinated-carbon\"><span data-contrast=\"none\">Pesticides Containing a Single Fluorinated Carbon<\/span><\/a><span data-contrast=\"none\"> is also referenced, which contains additional misleading and biased information. Even if EPA will not accept all fluorinated compounds as PFAS, there is scientific evidence connecting fluorinated pesticides to negative impacts on health and the environment.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">While EPA claims that \u201cExtensive scientific evidence and public input demonstrate molecules with only one fluorinated carbon generally lack the persistence and bioaccumulation properties that are commonly associated with forever chemicals,\u201d peer-reviewed (and not industry-supported) research shows\u00a0both persistence and health effects with exposure to fluorinated chemicals. As\u00a0stated\u00a0in\u00a0<\/span><a href=\"https:\/\/bp-dc.org\/bp-comments-on-fluoxapiprolin-september-2025\"><span data-contrast=\"none\">previous comments<\/span><\/a><span data-contrast=\"auto\">\u00a0to EPA, Beyond Pesticides notes that\u00a0fluorinated pesticides are a broad category of chemicals that encompass PFAS and\u00a0contain\u00a0very strong\u00a0carbon-fluorine bonds that are more resistant to degradation. Also of concern is the creation of additional fluorinated\u00a0degradates\u00a0(breakdown products) that have the potential to be more toxic than the parent compound.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Research in\u00a0<\/span><a href=\"https:\/\/scijournals.onlinelibrary.wiley.com\/doi\/full\/10.1002\/ps.7921\"><i><span data-contrast=\"none\">Pest Management Science<\/span><\/i><\/a><span data-contrast=\"auto\">\u00a0highlights that fluorinated molecules are often resistant to degradation,\u00a0representing\u00a0an environmental challenge with heightened risks to soil organisms. As the authors state, these chemicals are \u201csuspected of being environmental contaminants and\u00a0<\/span><a href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/category\/diseasehealth-effects\/endocrine-disruption\/\"><span data-contrast=\"none\">endocrine disruptors<\/span><\/a><span data-contrast=\"auto\">, although only a small number are currently\u00a0monitored\u00a0and regulated. However, due to limited epidemiological evidence, experimental toxicology studies, and mechanistic evidence,\u00a0many\u00a0of the specific functions, underlying mechanisms, and contributing factors\u00a0remain\u00a0poorly understood.\u201d<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">A study\u00a0this year\u00a0in\u00a0<\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1382668925001863\"><i><span data-contrast=\"none\">Environmental Toxicology and Pharmacology<\/span><\/i><\/a><span data-contrast=\"auto\">\u00a0finds concentration-dependent results with fluorine-containing pesticide exposure in earthworms. The data shows exposure elevates reactive oxygen species (ROS), activating antioxidant\u00a0enzymes\u00a0and increasing lipid peroxidation and DNA damage biomarkers. Mitochondrial function also declines, with impairments in energy metabolism.\u00a0Tissue damage within the epidermis, gut structures, and reproductive organs of the earthworms\u00a0is also noted, showing biochemical stress\u00a0as a result of\u00a0exposure to fluorinated pesticides.\u00a0All results\u00a0were heightened\u00a0at higher concentrations,\u00a0indicating\u00a0severe ecological threats.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">In 2020, fluorinated agrochemicals\u00a0comprised\u00a0about nine percent of the pesticide\u00a0market, and\u00a0have now reached almost 70 percent of\u00a0newly-approved\u00a0pesticides, according to a 2025 review in the\u00a0<\/span><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.jafc.4c12827\"><i><span data-contrast=\"none\">Journal of Agricultural and Food Chemistry<\/span><\/i><\/a><span data-contrast=\"auto\">.\u00a0Additionally, commentary\u00a0by Donley et al.\u00a0in\u00a0<\/span><a href=\"http:\/\/bp-dc.org\/forever-pesticides-cbd-peer-ewg-analysis-copy\"><i><span data-contrast=\"none\">Environmental Health Perspectives<\/span><\/i><\/a><span data-contrast=\"auto\">\u00a0showcases\u00a0how between 2012 and 2018, EPA granted 223 of 229 waiver requests (97%) for immunotoxicity testing of pesticide active ingredients. The article\u00a0states: \u201cTroublingly, the number of active ingredients that are fluorinated or that meet the definition of PFAS has increased\u00a0considerably from\u00a02012 to the present\u2014the very\u00a0time period\u00a0that the US EPA granted 97% of waiver requests for immunotoxicity study requirements. This suggests that fluorinated or PFAS active ingredients may be more likely to be\u00a0immunotoxic\u00a0than other types of active ingredients and that any associated immunotoxicity may not\u00a0be accounted\u00a0for owing to the lack of requirement for scientific study.\u201d<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Also on the\u00a0<\/span><a href=\"https:\/\/www.epa.gov\/ingredients-used-pesticide-products\/pesticides-containing-single-fluorinated-carbon\"><span data-contrast=\"none\">Pesticides Containing a Single Fluorinated Carbon<\/span><\/a><span data-contrast=\"auto\">\u00a0page, EPA states: \u201cAs part of its obligation to ensure that all pesticide products and uses are safe, EPA\u00a0evaluates them using gold-standard science, robust data requirements, and comprehensive assessment methodologies. This process ensures that EPA\u2019s pesticide reviews allow farmers and other users to have the tools they need to control pests to provide for a safe and abundant food supply while\u00a0maintaining\u00a0the highest standards to ensure human health and the environment\u00a0are protected.\u201d This messaging continues to ignore\u00a0<\/span><a href=\"https:\/\/www.beyondpesticides.org\/resources\/pesticide-induced-diseases-database\/overview\"><span data-contrast=\"none\">thousands of studies<\/span><\/a><span data-contrast=\"auto\">\u00a0that show currently registered pesticide active ingredients\u00a0are associated with\u00a0deleterious\u00a0and deadly implications for humans, wildlife, and all ecosystems.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"auto\">The Organic Solution<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">With EPA\u2019s failure to perform its statutory\u00a0duty\u00a0to adequately protect the health of the environment and all organisms within it, as\u00a0<\/span><a href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/index.php?s=EPA+failure\"><span data-contrast=\"none\">extensively covered<\/span><\/a><span data-contrast=\"none\">\u00a0by Beyond Pesticides, the call to truly safeguard ecosystems and public health with the elimination of pesticides, including all PFAS, takes on a greater urgency. Instead of creating a complicated workaround that will not address the urgent health, biodiversity, and climate crises, EPA must cancel registrations of pesticides that harm\u00a0health and the\u00a0environment and\u00a0facilitate\u00a0a widescale conversion to organic practices.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">The holistic, systems-based organic solution for land management and agriculture offers numerous <\/span><a href=\"https:\/\/www.beyondpesticides.org\/programs\/organic-agriculture\/why-organic\/health-benefits\"><span data-contrast=\"none\">health<\/span><\/a><span data-contrast=\"none\">\u00a0and\u00a0<\/span><a href=\"https:\/\/www.beyondpesticides.org\/programs\/organic-agriculture\/why-organic\/environmental-benefits\"><span data-contrast=\"none\">environmental<\/span><\/a><span data-contrast=\"none\">\u00a0benefits. Learn more about how to\u00a0take action\u00a0and have your voice heard on governmental efforts that are harmful to the environment and public and worker health, increase overall pesticide use, and undermine the advancement of organic, sustainable, and regenerative practices and policies\u00a0<\/span><a href=\"https:\/\/www.beyondpesticides.org\/action-of-the-week\"><span data-contrast=\"none\">here<\/span><\/a><span data-contrast=\"none\">.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Join us\u00a0<\/span><b><span data-contrast=\"none\">TODAY<\/span><\/b><span data-contrast=\"none\">\u00a0at\u00a01 PM\u00a0Eastern\u00a0for the\u00a0second session of Beyond Pesticides\u2019\u00a0<\/span><a href=\"https:\/\/www.beyondpesticides.org\/programs\/national-pesticide-forum\/2025-national-forum-series\/program\"><span data-contrast=\"none\">42<\/span><span data-contrast=\"none\">nd<\/span><span data-contrast=\"none\">\u00a0National Forum<\/span><\/a><span data-contrast=\"none\">, The Pesticide Threat to Environmental Health:\u00a0Advancing Holistic Solutions Aligned with Nature. The first session recordings and materials are available\u00a0<\/span><a href=\"https:\/\/www.beyondpesticides.org\/programs\/national-pesticide-forum\/2025-national-forum-series\/session-recordings-and-materials\"><span data-contrast=\"none\">here<\/span><\/a><span data-contrast=\"none\">.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><i><span data-contrast=\"none\">All unattributed positions and opinions in this piece are those of Beyond Pesticides.\u00a0<\/span><\/i><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><b><span data-contrast=\"none\">Sources<\/span><\/b><span data-contrast=\"none\">:<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">U.S. Environmental Protection Agency (2025). FACT CHECK: EPA Debunks False\u00a0Claims that\u00a0Agency Recently Approved \u2018Forever Chemical\u2019 Pesticides. Available at:\u00a0<\/span><a href=\"https:\/\/www.epa.gov\/newsreleases\/fact-check-epa-debunks-false-claims-agency-recently-approved-forever-chemical\"><span data-contrast=\"none\">https:\/\/www.epa.gov\/newsreleases\/fact-check-epa-debunks-false-claims-agency-recently-approved-forever-chemical<\/span><\/a><span data-contrast=\"none\">.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">U.S. Environmental Protection Agency (2025). Pesticides Containing a Single Fluorinated Carbon. Available at:\u00a0<\/span><a href=\"https:\/\/www.epa.gov\/ingredients-used-pesticide-products\/pesticides-containing-single-fluorinated-carbon\"><span data-contrast=\"none\">https:\/\/www.epa.gov\/ingredients-used-pesticide-products\/pesticides-containing-single-fluorinated-carbon<\/span><\/a><span data-contrast=\"none\">.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Kluger, J. (2025)\u00a0The\u00a0EPA Is Embracing PFAS Pesticides. These Are\u00a0The\u00a0Health Risks,\u00a0<\/span><i><span data-contrast=\"none\">Time<\/span><\/i><span data-contrast=\"none\">. Available at:\u00a0<\/span><a href=\"https:\/\/time.com\/7336883\/epa-pfas-pesticides-health-risks\/\"><span data-contrast=\"none\">https:\/\/time.com\/7336883\/epa-pfas-pesticides-health-risks\/<\/span><\/a><span data-contrast=\"none\">.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>(Beyond Pesticides, December\u00a04, 2025)\u00a0In a\u00a0news\u00a0release\u00a0last week\u00a0on November 26, 2025,\u00a0the U.S. Environmental Protection Agency (EPA) \u201cissued a comprehensive fact-check addressing dangerous misinformation circulating about EPA&#8217;s recent pesticide approvals\u201d that, according to health and\u00a0environmental advocates,\u00a0continues to deceive the public about the true risks for health and the environment from petrochemical pesticides including, but not limited to,\u00a0per- and polyfluoroalkyl substances (PFAS).\u00a0Also published on November 26, coverage titled\u00a0The EPA Is Embracing PFAS Pesticides. These Are The Health Risks\u00a0in\u00a0Time\u00a0further highlights EPA\u2019s deficiencies and the threats of PFAS, which Beyond Pesticides has extensively covered. (See\u00a0here\u00a0and\u00a0here.)\u00a0 The controversy erupted as a result of EPA\u2019s latest proposal to allow a new fluorinated pesticide to the list of four other similar compounds now widely available for use in homes and gardens, buildings, and agriculture. The newest pesticide proposed for EPA registration, epyrifenacil (agricultural weed killer), joins cyclobutrifluram (soil fungicide\/nematicide), isocycloseram (household and agricultural insecticide), diflufenican (lawn and agricultural weed killer), and trifludimoxazin (agricultural weed killer), making a total of five PFAS pesticide proposals this year that have been associated with national and worldwide contamination of food, land, and water. Two of these, cyclobutrifluram and isocycloseram, have been approved. \u201cInstead of constraining the use of fluorinated pesticides\u2014persistent and highly toxic [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":40452,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[249,196,350,293,354,484,492,6,10,515],"tags":[446,683,1625,605,1704,1003,717,1773,1771,1772,1176,715,2226,1361],"class_list":["post-40450","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-agriculture","category-cancer","category-contamination-2","category-developmental-disorders","category-environmental-protection-agency-epa","category-epigenetic","category-immunotoxicity","category-international","category-pesticide-regulation","category-pfas","tag-cancer","tag-contamination","tag-developmental-effects","tag-epa","tag-epa-failure","tag-epigenetic","tag-forever-chemicals","tag-immunotoxicity","tag-persistent","tag-pesticide-contamination","tag-pesticide-regulation","tag-pfas","tag-regulatory-deficiencies","tag-regulatory-failure"],"yoast_head":"<!-- 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