{"id":41737,"date":"2026-06-03T00:01:33","date_gmt":"2026-06-03T04:01:33","guid":{"rendered":"https:\/\/beyondpesticides.org\/dailynewsblog\/?p=41737"},"modified":"2026-06-01T13:24:32","modified_gmt":"2026-06-01T17:24:32","slug":"widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress","status":"publish","type":"post","link":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/","title":{"rendered":"Widely Used Fungicide and Breakdown Products Threaten Consumers and Wildlife by Triggering Oxidative Stress"},"content":{"rendered":"

(<\/span>Beyond Pesticides<\/span><\/i>, June 3, 2026)\u00a0A study, published in\u00a0<\/span>PeerJ<\/span><\/i> today, by researchers from the University of Wisconsin-Madison in the U.S. and the University of Pisa in Italy, finds that the widely used fungicide\u00a0<\/span>fludioxonil<\/span><\/a> and its breakdown products, including\u00a0a \u2018forever chemical\u2019\u00a0per- and poly-fluoroalkyl substance\u00a0(<\/span>PFAS<\/span><\/a>), threaten environmental and human health. Through a review of scientific literature (from 2021-2025) of the ecological and health effects of fludioxonil, the authors find evidence of this chemical\u2019s mechanisms of toxicity, including <\/span>oxidative stress<\/span><\/a>,\u00a0that are enhanced as it\u00a0degrades\u00a0in the environment.<\/span>\u00a0<\/span>Oxidative stress<\/span><\/a>\u202foccurs when there is a disruption of normal cell-signaling and molecular damage, leading to an imbalance of reactive oxygen species (ROS) and free radicals (unstable oxygen molecules) that the body is unable to detoxify.\u202fIn particular, sunlight\u00a0exposure causes\u00a0fludioxonil to break down into a PFAS that is linked to\u00a0adverse\u00a0health\u00a0implications for\u00a0the environment, wildlife, and\u00a0humans.<\/span>\u00a0<\/span><\/p>\n

One of the authors,\u00a0Warren Porter, PhD, is a\u00a0<\/span>board member<\/span><\/a>\u00a0for\u00a0Beyond Pesticides and\u00a0presented at the\u00a0<\/span>2021\u00a0National\u00a0Pesticide\u00a0Forum<\/span><\/a>.\u00a0Dr. Porter is an emeritus Professor of Integrative Biology and\u00a0an Ardath\u00a0and Robert Rodale Professor of Environmental Toxicology, with\u00a0previous\u00a0research showing that combinations of commonly used agricultural chemicals in concentrations that mirror levels found in groundwater can significantly influence immune, endocrine,\u00a0and neurological health in animals. His\u00a0<\/span>research<\/span><\/a>\u00a0also\u00a0links pesticide exposure in utero to impaired learning, changes in brain function,\u00a0and altered thyroid levels.<\/span>\u00a0<\/span><\/p>\n

Importance\u00a0and\u00a0Background<\/span><\/b>\u00a0<\/span><\/p>\n

Fludioxonil, originally developed by Ciba-Geigy (now Syngenta) in 1993, was created as a preservative and anti-fungal coating for seed storage before being registered as a multi-use fungicide. The original data indicated that fludioxonil \u201cfunctioned by acting directly upon a single enzyme, a kinase that was unique to specific species of fungi,\u201d which suggested that the compound would not harm nontarget organisms. Fludioxonil was also described as being \u201cresistant to UV photolysis\/hydrolysis [degradation pathways using sunlight] and free from concerns regarding toxic synergy with other pesticides,\u201d which led to an increase in usage for a myriad of applications.<\/span>\u00a0<\/span><\/p>\n

In the\u00a0U.S. alone,\u00a0fludioxonil\u00a0is\u00a0<\/span>registered<\/span><\/a> for use on over 900 different types of plants, including a wide array of field and vegetable crops, fruit trees, berries, herbs, and grasses. This compound can be used for large-scale applications with sprayers on crops to prevent fungal infections during growth, as well as in post-harvest applications to prevent mold in transport.\u00a0<\/span>One study<\/span><\/a> finds that fludioxonil is among the seven pesticides most likely to reach consumers through residues in food, while <\/span>additional research<\/span><\/a>\u00a0shows this fungicide is frequently found in imported produce at levels that surpass regulatory limits.<\/span>\u00a0<\/span><\/p>\n

“The highly hydrophobic fungicide is\u00a0particularly difficult to wash off of produce, ensuring that a substantial percentage of the\u00a0fungicide used in treatment remains on food at time of consumption,\u201d the review\u00a0authors\u00a0state. As they point out, even though fludioxonil is often added to produce\u00a0after\u00a0it has been boxed for shipment, it is not considered a food additive\u00a0by the U.S. Food and Drug Administration (FDA) and is only regulated through the U.S.\u00a0Environmental Protection Agency (EPA). EPA, however, \u201cdoes not distinguish this form of concentrated application from\u00a0pesticides that may take days or even weeks to be degraded in the field, detoxified or leached\u00a0from the surface of produce by natural actions of sunlight, wind, rain and metabolism by\u00a0microorganisms,\u201d leaving high levels of this pesticide on products that are directly ingested by consumers.<\/span>\u00a0<\/span><\/p>\n

Methodology\u00a0and\u00a0Results<\/span><\/b>\u00a0<\/span><\/p>\n

In this review,\u00a0the researchers analyze evidence that\u00a0fludioxonil poses a threat to both ecosystems and human health\u00a0within scientific literature. The results reveal that\u00a0the mechanism of toxicity that\u00a0causes\u00a0adverse effects\u00a0is\u00a0based on the\u00a0fungicide\u2019s\u00a0ability to\u00a0induce oxidative stress\u00a0by exhausting\u00a0levels of glutathione (GSH).<\/span>\u00a0<\/span><\/p>\n

Through the research available in\u00a0peer-reviewed articles, patents,\u00a0and\u00a0policy\u00a0documents,\u00a0among others,\u00a0fludioxonil is shown to\u00a0disrupt GSH homeostasis, which serves to buffer against oxidative stress. \u201cGlutathione depletion via\u00a0fludioxonil may thus comprise a key mechanism for its toxicity in living organisms,\u201d the authors explain.\u00a0<\/span>\u00a0<\/span><\/p>\n

They continue: \u201cIt should be emphasized here that the biological functions of GSH are critically important as\u00a0this tripeptide serves as the master\u00a0antioxidant\u00a0in animals, plants and fungi, protecting them\u00a0from oxidative damage derived from stress, pollution and disease.\u201d (See research\u00a0<\/span>here<\/span><\/a>\u00a0and\u00a0<\/span>here<\/span><\/a>.)<\/span>\u00a0<\/span><\/p>\n

This process is particularly driven by a breakdown product of fludioxonil that is formed under the UV radiation present in sunlight. As the researchers share, \u201cOf note, while the toxicity of many pesticides is reduced by environmental forces such as the UV rays in sunlight, fludioxonil seems to behave in the opposite manner.\u201d (See <\/span>here<\/span><\/a>.)\u00a0The breakdown products generated after exposure to sunlight are \u201capproximately 100-fold more toxic than the parent compound,\u201d highlighting the\u00a0additional\u00a0concerns as pesticide active ingredients degrade in the environment.<\/span>\u00a0<\/span><\/p>\n

Previous\u00a0Research<\/span><\/b>\u00a0<\/span><\/p>\n

A 2018 survey<\/span><\/a>\u00a0by the Environmental Working Group of pesticide levels in common brands of baby food finds that the levels of fludioxonil significantly exceed the Maximum Residue Level (MRL)\u00a0established\u00a0by EPA.\u00a0A\u00a0<\/span>repeat of the study in 2023<\/span><\/a>\u00a0again finds\u00a0fludioxonil, and other pesticides, present in multiple baby food\u00a0samples. (See\u00a0<\/span>Daily News<\/span><\/i>\u00a0<\/span>here<\/span><\/a>.)\u00a0Additional\u00a0studies\u00a0cited within the review\u00a0find that nontarget organisms are also at risk, including\u00a0<\/span>aquatic organisms<\/span><\/a>, <\/span>phytoplankton<\/span><\/a>, <\/span>plants<\/span><\/a>, <\/span>bacteria<\/span><\/a>,\u00a0<\/span>benthic macroinvertebrates<\/span><\/a>,\u00a0<\/span>amphibians<\/span><\/a>,\u00a0<\/span>honey bees<\/span><\/a>,\u00a0<\/span>terrestrial earthworms<\/span><\/a>\u00a0and\u00a0<\/span>nematodes<\/span><\/a>, and large mammals, including\u00a0<\/span>humans<\/span><\/a>.<\/span>\u00a0<\/span><\/p>\n

A Daily News <\/span><\/i>post,<\/span><\/i>\u00a0entitled\u00a0<\/span>Widely Used Fungicide Found to Adversely Affect Enzyme Common to All Cells<\/span><\/a>,\u00a0documents\u00a0how\u00a0a study\u00a0in\u00a0<\/span>Scientific Reports<\/span><\/i><\/a>, with research led by Tristan Brandhorst, PhD (an author on the current study), sheds light on a mechanism of toxicity for fludioxonil as it acts on a sugar-metabolizing enzyme common to all cells. This mechanism threatens all organisms, proving the initial claims that fludioxonil acts solely on specific species of fungi incorrect. Additional <\/span>research<\/span><\/a>\u00a0by Dr. Brandhorst\u00a0suggests that fludioxonil also decreases the human body\u2019s ability to defend itself against illnesses, like COVID-19, and promotes disease permanency. This\u00a0lack of bodily defense against disease\u00a0is linked to the pesticide-induced reduction in the antioxidant\u00a0GSH, further\u00a0supported by\u00a0the current review.<\/span>\u00a0<\/span><\/p>\n

Although\u00a0<\/span>previous studies<\/span><\/a> report that fludioxonil disrupts hepatic (liver), endocrine, and neurological systems, the mode of action by which this fungicide causes these issues only recently\u00a0came to light. According to research by Dr. Brandhorst, fludioxonil may impede the antioxidant GSH from protecting the body from illnesses while prompting disease endurance, as GSH\u00a0is a natural antioxidant important in blood pressure and glucose regulation, preventing the formation of free radicals which damage cells in hypertension and diabetes mellitus. However, the endocrine disruption properties of fludioxonil can cause intracellular\u00a0GSH\u00a0deficiency, resulting in oxidative stress that influences the development of diseases, including Alzheimer\u2019s disease, liver disease, cancer, diabetes, and more. A decrease in\u00a0GSH\u00a0biosynthesis and\/or an increase in depletion of the intracellular\u00a0GSH\u00a0pool can impair oxidation-reduction homeostasis and promote oxidative stress that may account for individual susceptibility to a disease like COVID-19.\u00a0(See\u00a0<\/span>Daily News<\/span><\/i>\u00a0<\/span>here<\/span><\/a>, as well as\u00a0additional\u00a0coverage on\u00a0fludioxonil\u00a0<\/span>here<\/span><\/a>.)<\/span>\u00a0<\/span><\/p>\n

The Path Forward<\/span><\/b>\u00a0<\/span><\/p>\n

Removing all petrochemical pesticides and synthetic fertilizers\u00a0will\u00a0protect the environment, all wildlife, and human health. Having fungicides like fludioxonil on crops, during and after harvest, leads\u00a0to\u00a0deleterious\u00a0impacts on the soil, ecosystems, and all organisms, with heightened risks associated with PFAS breakdown products when fludioxonil is degraded by sunlight. The\u00a0health and environmental threats associated with this fungicide, as well as all other pesticide active ingredients, are far beyond the\u00a0“unreasonable adverse effects” as outlined by the\u00a0<\/span>Federal Insecticide, Fungicide, and Rodenticide Act<\/span><\/i>\u00a0(FIFRA).<\/span>\u00a0<\/span><\/p>\n

Food choices<\/span><\/a>\u00a0have a direct effect on the health of\u00a0the\u00a0environment and those who grow and harvest what\u00a0consumers\u00a0eat.\u00a0That\u2019s\u00a0why food labeled “organic” is the right choice. In addition to serious health questions linked to actual residues of toxic pesticides on the food we eat, our food buying decisions support or reject hazardous agricultural practices, protection of farmworkers and farm families, and stewardship of the earth.\u00a0<\/span>\u00a0<\/span><\/p>\n

It is important to eat organic food\u2014nurtured in a system of food production, handling, and certification that rejects hazardous synthetic chemicals. USDA organic certification is the only system of food labeling that is subject to independent public review and oversight, assuring consumers that toxic, synthetic pesticides used in conventional agriculture are replaced by management practices focused on soil biology, biodiversity, and plant health. This eliminates commonly used toxic chemicals in the production and processing of food that is not labeled\u00a0organic<\/span>\u2014<\/span>pesticides that contaminate water and air, hurt biodiversity, harm farmworkers, and kill bees, birds, fish, and other wildlife.<\/span>\u00a0<\/span><\/p>\n

Adopting a fully organic diet can\u00a0also\u00a0reduce pesticide levels within the body, as well as\u00a0facilitate\u00a0faster DNA damage repair, according to findings from a randomized clinical trial published in\u00a0<\/span>Nutrire<\/span><\/i><\/a>.\u00a0(See\u00a0<\/span>Study Demonstrates Health Benefits of Organic Diet Over That Consumed with Toxic Pesticides<\/span><\/a>\u00a0for more information.)\u00a0Learn\u00a0about\u00a0additional\u00a0health and environmental benefits of organic practices\u00a0<\/span>here<\/span><\/a>\u00a0and\u00a0<\/span>here<\/span><\/a>, as well as how to\u00a0<\/span>Grow Your Own Organic Food<\/span><\/a>.<\/span>\u00a0<\/span><\/p>\n

All unattributed positions and opinions in this piece are those of Beyond Pesticides.\u00a0<\/span><\/i>\u00a0<\/span><\/p>\n

Source<\/span><\/b>:<\/span>\u00a0<\/span><\/p>\n

Roelans, L.,\u00a0Brandhorst, T, Tonelli, M., Chiellini, G., and Porter, W. (2026)\u00a0Breakdown\u00a0products of the fungicide Fludioxonil may account for\u00a0observed\u00a0environmental impact: potential implications for human health,\u00a0<\/span>PeerJ<\/span><\/i>. Available at:\u00a0<\/span>https:\/\/peerj.com\/journals\/peerj\/<\/span><\/a>.<\/span>\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

(Beyond Pesticides, June 3, 2026)\u00a0A study, published in\u00a0PeerJ today, by researchers from the University of Wisconsin-Madison in the U.S. and the University of Pisa in Italy, finds that the widely used fungicide\u00a0fludioxonil and its breakdown products, including\u00a0a \u2018forever chemical\u2019\u00a0per- and poly-fluoroalkyl substance\u00a0(PFAS), threaten environmental and human health. Through a review of scientific literature (from 2021-2025) of the ecological and health effects of fludioxonil, the authors find evidence of this chemical\u2019s mechanisms of toxicity, including oxidative stress,\u00a0that are enhanced as it\u00a0degrades\u00a0in the environment.\u00a0Oxidative stress\u202foccurs when there is a disruption of normal cell-signaling and molecular damage, leading to an imbalance of reactive oxygen species (ROS) and free radicals (unstable oxygen molecules) that the body is unable to detoxify.\u202fIn particular, sunlight\u00a0exposure causes\u00a0fludioxonil to break down into a PFAS that is linked to\u00a0adverse\u00a0health\u00a0implications for\u00a0the environment, wildlife, and\u00a0humans.\u00a0 One of the authors,\u00a0Warren Porter, PhD, is a\u00a0board member\u00a0for\u00a0Beyond Pesticides and\u00a0presented at the\u00a02021\u00a0National\u00a0Pesticide\u00a0Forum.\u00a0Dr. Porter is an emeritus Professor of Integrative Biology and\u00a0an Ardath\u00a0and Robert Rodale Professor of Environmental Toxicology, with\u00a0previous\u00a0research showing that combinations of commonly used agricultural chemicals in concentrations that mirror levels found in groundwater can significantly influence immune, endocrine,\u00a0and neurological health in animals. His\u00a0research\u00a0also\u00a0links pesticide exposure in utero to impaired learning, changes in brain function,\u00a0and […]<\/p>\n","protected":false},"author":2,"featured_media":41739,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[249,619,420,374,2384,528,399,10,515,166],"tags":[2375,2480,1251,1142,1997,2171,1269,715,1698,667],"class_list":["post-41737","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-agriculture","category-breakdown-chemicals","category-fludioxonil","category-fungicides","category-italy","category-metabolites","category-oxidative-stress","category-pesticide-regulation","category-pfas","category-syngenta","tag-breakdown-product","tag-consumers","tag-degradation","tag-fludioxonil","tag-fungicides","tag-nontarget-organisms","tag-oxidative-stress","tag-pfas","tag-syngenta","tag-wildlife"],"yoast_head":"\nWidely Used Fungicide and Breakdown Products Threaten Consumers and Wildlife by Triggering Oxidative Stress - Beyond Pesticides Daily News Blog<\/title>\n<meta name=\"description\" content=\"Fludioxonil and the breakdown products created as it degrades in the environment cause oxidative stress, as shown in a new scientific review.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Widely Used Fungicide and Breakdown Products Threaten Consumers and Wildlife by Triggering Oxidative Stress - Beyond Pesticides Daily News Blog\" \/>\n<meta property=\"og:description\" content=\"Fludioxonil and the breakdown products created as it degrades in the environment cause oxidative stress, as shown in a new scientific review.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/\" \/>\n<meta property=\"og:site_name\" content=\"Beyond Pesticides Daily News Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/beyondpesticides\" \/>\n<meta property=\"article:author\" content=\"https:\/\/www.facebook.com\/beyondpesticides\/\" \/>\n<meta property=\"article:published_time\" content=\"2026-06-03T04:01:33+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2026\/06\/DN-6.3.26.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Beyond Pesticides\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@ByondPesticides\" \/>\n<meta name=\"twitter:site\" content=\"@ByondPesticides\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Beyond Pesticides\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/\"},\"author\":{\"name\":\"Beyond Pesticides\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/person\/1b5c0a0981b549cc5b628770073031f4\"},\"headline\":\"Widely Used Fungicide and Breakdown Products Threaten Consumers and Wildlife by Triggering Oxidative Stress\",\"datePublished\":\"2026-06-03T04:01:33+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/\"},\"wordCount\":1571,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#organization\"},\"image\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2026\/06\/DN-6.3.26.jpg\",\"keywords\":[\"breakdown product\",\"consumers\",\"degradation\",\"Fludioxonil\",\"fungicides\",\"nontarget organisms\",\"oxidative stress\",\"PFAS\",\"Syngenta\",\"wildlife\"],\"articleSection\":[\"Agriculture\",\"Breakdown Chemicals\",\"fludioxonil\",\"Fungicides\",\"Italy\",\"Metabolites\",\"Oxidative Stress\",\"Pesticide Regulation\",\"PFAS\",\"Syngenta\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/\",\"url\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/\",\"name\":\"Widely Used Fungicide and Breakdown Products Threaten Consumers and Wildlife by Triggering Oxidative Stress - Beyond Pesticides Daily News Blog\",\"isPartOf\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2026\/06\/DN-6.3.26.jpg\",\"datePublished\":\"2026-06-03T04:01:33+00:00\",\"description\":\"Fludioxonil and the breakdown products created as it degrades in the environment cause oxidative stress, as shown in a new scientific review.\",\"breadcrumb\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#primaryimage\",\"url\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2026\/06\/DN-6.3.26.jpg\",\"contentUrl\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2026\/06\/DN-6.3.26.jpg\",\"width\":1920,\"height\":1080,\"caption\":\"Fludioxonil and the breakdown products created as it degrades in the environment cause oxidative stress, as shown in a new scientific review.\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Widely Used Fungicide and Breakdown Products Threaten Consumers and Wildlife by Triggering Oxidative Stress\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#website\",\"url\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/\",\"name\":\"Beyond Pesticides Daily News Blog\",\"description\":\"News on Pesticide Science, Policy and Activism\",\"publisher\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#organization\",\"name\":\"Beyond Pesticides\",\"url\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2023\/05\/BeyondPesticides-Logo-Stacked-scaled.jpg\",\"contentUrl\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2023\/05\/BeyondPesticides-Logo-Stacked-scaled.jpg\",\"width\":2560,\"height\":2501,\"caption\":\"Beyond Pesticides\"},\"image\":{\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/beyondpesticides\",\"https:\/\/x.com\/ByondPesticides\",\"https:\/\/www.instagram.com\/beyondpesticides\/?hl=en\",\"https:\/\/www.linkedin.com\/company\/beyond-pesticides\",\"https:\/\/www.youtube.com\/user\/bpncamp\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/person\/1b5c0a0981b549cc5b628770073031f4\",\"name\":\"Beyond Pesticides\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/e26b7558fcb265e244c6e159abe5f0aab551822dc82fd0b1607e809bdfbed20a?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/e26b7558fcb265e244c6e159abe5f0aab551822dc82fd0b1607e809bdfbed20a?s=96&d=mm&r=g\",\"caption\":\"Beyond Pesticides\"},\"description\":\"Beyond Pesticides is a 501(c)3 nonprofit organization headquartered in Washington, D.C., which works with allies in protecting public health and the environment to lead the transition to a world free of toxic pesticides. The founders, who established Beyond Pesticides (originally as National Coalition Against the Misuse of Pesticides) as a nonprofit membership organization in 1981, felt that without the existence of such an organized, national network, local, state and national pesticide policy would become, under chemical industry pressure, increasingly unresponsive to public health and environmental concerns. Beyond Pesticides believes that people must have a voice in decisions that affect them directly. We believe decisions should not be made for us by chemical companies or by decision-makers who either do not have all of the facts or refuse to consider them. Learn more about our work, read A Year in Review\u20142021, our accomplishments are your victories! Beyond Pesticides seeks to protect healthy air, water, land, and food for ourselves and future generations. By forging ties with governments, nonprofits, and people who rely on these natural resources, we reduce the need for unnecessary pesticide use and protect public health and the environment. Beyond Pesticides provides hands-on services to the public and supports local action by: identifying and interpreting hazards; and, designing safe pest management programs. With the information provided by Beyond Pesticides, people may not only be able to make informed choices and adopt practices that protect themselves and their families from unnecessary exposure to pesticides, but they will be able to effect changes on community-wide pest management decisions and policies that govern pesticide use, such as pesticide uses in parks, schools, for community insect control and along roadsides. Beyond Pesticides believes that people must have a voice in decisions which affect them directly.\",\"sameAs\":[\"https:\/\/www.beyondpesticides.org\",\"https:\/\/www.facebook.com\/beyondpesticides\/\",\"https:\/\/www.instagram.com\/beyondpesticides\/\",\"https:\/\/www.linkedin.com\/company\/beyond-pesticides\/\",\"https:\/\/x.com\/ByondPesticides\",\"https:\/\/www.youtube.com\/user\/bpncamp\/\"],\"url\":\"https:\/\/beyondpesticides.org\/dailynewsblog\/author\/beyond-pesticides\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Widely Used Fungicide and Breakdown Products Threaten Consumers and Wildlife by Triggering Oxidative Stress - Beyond Pesticides Daily News Blog","description":"Fludioxonil and the breakdown products created as it degrades in the environment cause oxidative stress, as shown in a new scientific review.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/","og_locale":"en_US","og_type":"article","og_title":"Widely Used Fungicide and Breakdown Products Threaten Consumers and Wildlife by Triggering Oxidative Stress - Beyond Pesticides Daily News Blog","og_description":"Fludioxonil and the breakdown products created as it degrades in the environment cause oxidative stress, as shown in a new scientific review.","og_url":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/","og_site_name":"Beyond Pesticides Daily News Blog","article_publisher":"https:\/\/www.facebook.com\/beyondpesticides","article_author":"https:\/\/www.facebook.com\/beyondpesticides\/","article_published_time":"2026-06-03T04:01:33+00:00","og_image":[{"width":1920,"height":1080,"url":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2026\/06\/DN-6.3.26.jpg","type":"image\/jpeg"}],"author":"Beyond Pesticides","twitter_card":"summary_large_image","twitter_creator":"@ByondPesticides","twitter_site":"@ByondPesticides","twitter_misc":{"Written by":"Beyond Pesticides","Est. reading time":"7 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#article","isPartOf":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/"},"author":{"name":"Beyond Pesticides","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/person\/1b5c0a0981b549cc5b628770073031f4"},"headline":"Widely Used Fungicide and Breakdown Products Threaten Consumers and Wildlife by Triggering Oxidative Stress","datePublished":"2026-06-03T04:01:33+00:00","mainEntityOfPage":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/"},"wordCount":1571,"commentCount":0,"publisher":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#organization"},"image":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#primaryimage"},"thumbnailUrl":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2026\/06\/DN-6.3.26.jpg","keywords":["breakdown product","consumers","degradation","Fludioxonil","fungicides","nontarget organisms","oxidative stress","PFAS","Syngenta","wildlife"],"articleSection":["Agriculture","Breakdown Chemicals","fludioxonil","Fungicides","Italy","Metabolites","Oxidative Stress","Pesticide Regulation","PFAS","Syngenta"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/","url":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/","name":"Widely Used Fungicide and Breakdown Products Threaten Consumers and Wildlife by Triggering Oxidative Stress - Beyond Pesticides Daily News Blog","isPartOf":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#website"},"primaryImageOfPage":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#primaryimage"},"image":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#primaryimage"},"thumbnailUrl":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2026\/06\/DN-6.3.26.jpg","datePublished":"2026-06-03T04:01:33+00:00","description":"Fludioxonil and the breakdown products created as it degrades in the environment cause oxidative stress, as shown in a new scientific review.","breadcrumb":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#primaryimage","url":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2026\/06\/DN-6.3.26.jpg","contentUrl":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2026\/06\/DN-6.3.26.jpg","width":1920,"height":1080,"caption":"Fludioxonil and the breakdown products created as it degrades in the environment cause oxidative stress, as shown in a new scientific review."},{"@type":"BreadcrumbList","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2026\/06\/widely-used-fungicide-and-breakdown-products-threaten-consumers-and-wildlife-by-triggering-oxidative-stress\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/beyondpesticides.org\/dailynewsblog\/"},{"@type":"ListItem","position":2,"name":"Widely Used Fungicide and Breakdown Products Threaten Consumers and Wildlife by Triggering Oxidative Stress"}]},{"@type":"WebSite","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#website","url":"https:\/\/beyondpesticides.org\/dailynewsblog\/","name":"Beyond Pesticides Daily News Blog","description":"News on Pesticide Science, Policy and Activism","publisher":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/beyondpesticides.org\/dailynewsblog\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#organization","name":"Beyond Pesticides","url":"https:\/\/beyondpesticides.org\/dailynewsblog\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/logo\/image\/","url":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2023\/05\/BeyondPesticides-Logo-Stacked-scaled.jpg","contentUrl":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-content\/uploads\/2023\/05\/BeyondPesticides-Logo-Stacked-scaled.jpg","width":2560,"height":2501,"caption":"Beyond Pesticides"},"image":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/beyondpesticides","https:\/\/x.com\/ByondPesticides","https:\/\/www.instagram.com\/beyondpesticides\/?hl=en","https:\/\/www.linkedin.com\/company\/beyond-pesticides","https:\/\/www.youtube.com\/user\/bpncamp"]},{"@type":"Person","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/person\/1b5c0a0981b549cc5b628770073031f4","name":"Beyond Pesticides","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/e26b7558fcb265e244c6e159abe5f0aab551822dc82fd0b1607e809bdfbed20a?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/e26b7558fcb265e244c6e159abe5f0aab551822dc82fd0b1607e809bdfbed20a?s=96&d=mm&r=g","caption":"Beyond Pesticides"},"description":"Beyond Pesticides is a 501(c)3 nonprofit organization headquartered in Washington, D.C., which works with allies in protecting public health and the environment to lead the transition to a world free of toxic pesticides. The founders, who established Beyond Pesticides (originally as National Coalition Against the Misuse of Pesticides) as a nonprofit membership organization in 1981, felt that without the existence of such an organized, national network, local, state and national pesticide policy would become, under chemical industry pressure, increasingly unresponsive to public health and environmental concerns. Beyond Pesticides believes that people must have a voice in decisions that affect them directly. We believe decisions should not be made for us by chemical companies or by decision-makers who either do not have all of the facts or refuse to consider them. Learn more about our work, read A Year in Review\u20142021, our accomplishments are your victories! Beyond Pesticides seeks to protect healthy air, water, land, and food for ourselves and future generations. By forging ties with governments, nonprofits, and people who rely on these natural resources, we reduce the need for unnecessary pesticide use and protect public health and the environment. Beyond Pesticides provides hands-on services to the public and supports local action by: identifying and interpreting hazards; and, designing safe pest management programs. With the information provided by Beyond Pesticides, people may not only be able to make informed choices and adopt practices that protect themselves and their families from unnecessary exposure to pesticides, but they will be able to effect changes on community-wide pest management decisions and policies that govern pesticide use, such as pesticide uses in parks, schools, for community insect control and along roadsides. Beyond Pesticides believes that people must have a voice in decisions which affect them directly.","sameAs":["https:\/\/www.beyondpesticides.org","https:\/\/www.facebook.com\/beyondpesticides\/","https:\/\/www.instagram.com\/beyondpesticides\/","https:\/\/www.linkedin.com\/company\/beyond-pesticides\/","https:\/\/x.com\/ByondPesticides","https:\/\/www.youtube.com\/user\/bpncamp\/"],"url":"https:\/\/beyondpesticides.org\/dailynewsblog\/author\/beyond-pesticides\/"}]}},"_links":{"self":[{"href":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-json\/wp\/v2\/posts\/41737","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-json\/wp\/v2\/comments?post=41737"}],"version-history":[{"count":4,"href":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-json\/wp\/v2\/posts\/41737\/revisions"}],"predecessor-version":[{"id":41751,"href":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-json\/wp\/v2\/posts\/41737\/revisions\/41751"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-json\/wp\/v2\/media\/41739"}],"wp:attachment":[{"href":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-json\/wp\/v2\/media?parent=41737"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-json\/wp\/v2\/categories?post=41737"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/beyondpesticides.org\/dailynewsblog\/wp-json\/wp\/v2\/tags?post=41737"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}