{"id":4509,"date":"2010-11-10T01:01:50","date_gmt":"2010-11-10T05:01:50","guid":{"rendered":"https:\/\/www.beyondpesticides.org\/dailynewsblog\/?p=4509"},"modified":"2010-11-09T23:09:46","modified_gmt":"2010-11-10T03:09:46","slug":"triclosan-exposure-raises-pregnancy-concerns","status":"publish","type":"post","link":"https:\/\/beyondpesticides.org\/dailynewsblog\/2010\/11\/triclosan-exposure-raises-pregnancy-concerns\/","title":{"rendered":"Triclosan Exposure Raises Pregnancy Concerns"},"content":{"rendered":"

(Beyond Pesticides<\/em>, November 10, 2010) A University of Florida, Gainesville study reports that the antibacterial pesticide triclosan, found in toothpaste, soaps, toys and clothing, interferes with estrogen metabolism in women and can disrupt a vital enzyme during pregnancy. These recent findings raise concerns about triclosan\u2019s possible effects on fetal growth and development. This study is just one of an emerging body of science which supports triclosan as an endocrine disruptor and should be eliminated from consumer products. \"\"<\/a><\/p>\n

The study<\/a>, which was published in the November print issue of the journal Environment International<\/em>, examines the effect of triclosan<\/a> on a placental enzyme, called estrogen sulfotransferase. Triclosan is known to inhibit sulfonation of phenolic xenobiotics and is structurally related to other known inhibitors of estrogen sulfotransferase, such as polychlorobiphenylols (PCBs). During pregnancy, the placenta is an important source of estrogen, which is needed for normal fetal development and successful parturition (childbirth), and estrogen sulfotransferase is thought to play an important role in regulation of estrogen availability. Estrogen is a key hormone during pregnancy and controls the way a baby develops many key organs like the brain. Triclosan was found to be a very potent inhibitor of both estradiol and estrone sulfonation. The high potency of triclosan as an inhibitor of estrogen sulfotransferase activity raises concern about its possible effects on the ability of the placenta to supply estrogen to the fetus. <\/p>\n

Aside from the role it plays in the fetus, estrogen also affects how much oxygen the baby gets from the mother. Estrogen is also involved in signaling the uterus to contract during labor. But maintaining the right levels of the hormone during pregnancy is a delicate balance. Too much estrogen could send the mother\u2019s body into premature labor. Too little could hinder the flow of oxygen. Both instances could affect how the baby\u2019s brain develops. This is one of the reasons scientists are concerned about the pregnancy-related effects of chemicals such as triclosan. <\/p>\n

According to Margaret James, PhD, University of Florida medicinal chemist and lead author of the study, \u201cWe suspect that makes this substance dangerous in pregnancy if enough of the triclosan gets through to the placenta to affect the enzyme. We know for sure it is a very potent inhibitor. What we don\u2019t know is the kinds of levels you would have to be exposed to see a negative effect. If this process is interrupted then we wonder if that might affect how the fetus develops. There is a chance it may not produce some of the proteins that it should during development. Therefore there might be a chance at either growth retardation or something worse happening to the fetus.\u201d <\/p>\n

\u201cMy recommendation would be if someone is pregnant that the best thing would be to avoid plaque reducing toothpastes that has Triclosan in it and also to avoid antibacterial soaps and other products that have Triclosan in it,\u201d Dr. James also added.<\/p>\n

Researchers are also concerned that some people cannot get rid of all the triclosan from their bodies once exposed. Research shows that just a small amount of triclosan can be potentially damaging to a developing baby. Triclosan has already been found in breast milk<\/a>, urine<\/a> and umbilical cord blood. The Centers for Disease Control in an updated National Report on Human Exposure to Environmental Chemicals notes that triclosan levels in people increased<\/a> by over 41% between just the years 2004 and 2006. It is the antimicrobial agent in hundreds of consumer products<\/a> currently on the market including hand sanitizers, toys, clothing and kitchen utensils. Triclosan is an endocrine disruptor and has been shown to affect male and female reproductive hormones and is also shown to alter thyroid function<\/a>. Triclosan is one of the most detected<\/a> chemicals in U.S. waterways; about 96 percent of triclosan from consumer products is disposed of in residential drains. This leads to large loads of the chemical in water entering wastewater treatment plants, which are incompletely removed during the wastewater treatment process. When treated wastewater is released to the environment, sunlight converts some of the triclosan (and related compounds) into various forms of dioxins<\/a>. <\/p>\n

Based on these numerous human and environmental health concerns, Beyond Pesticides in partnership with Food and Water Watch and 78 other groups, submitted petitions<\/a> to both the Food and Drug Administration (FDA) and U.S. Environmental Protection Agency (EPA) requiring that they ban all non-medically prescribed triclosan uses on the basis that those uses violate several federal statutes. FDA recently stated <\/a>that \u201cexisting data raise valid concerns about the [health] effects of repetitive daily human exposure to these antiseptic ingredients.\u201d FDA announced that it plans to review data concerning triclosan. EPA maintains that the agency does not currently plan to reevaluate its regulations surrounding the use of triclosan until 2013. [Triclosan is jointly regulated by FDA and EPA.]<\/p>\n

TAKE ACTION:<\/strong> Join the ban triclosan campaign<\/a> and sign the pledge<\/a> to stop using triclosan today. Avoid products containing triclosan, and encourage your local schools, government agencies, and local businesses to use their buying power to go triclosan-free. Urge your municipality, institution or company to adopt the model resolution<\/a> which commits to not procuring or using products containing triclosan. For more information about triclosan and the campaign, visit our Triclosan program page<\/a>. <\/p>\n

Source: University of Florida News<\/a> <\/em>
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(Beyond Pesticides, November 10, 2010) A University of Florida, Gainesville study reports that the antibacterial pesticide triclosan, found in toothpaste, soaps, toys and clothing, interferes with estrogen metabolism in women and can disrupt a vital enzyme during pregnancy. These recent findings raise concerns about triclosan\u2019s possible effects on fetal growth and development. This study is just one of an emerging body of science which supports triclosan as an endocrine disruptor and should be eliminated from consumer products. The study, which was published in the November print issue of the journal Environment International, examines the effect of triclosan on a placental enzyme, called estrogen sulfotransferase. Triclosan is known to inhibit sulfonation of phenolic xenobiotics and is structurally related to other known inhibitors of estrogen sulfotransferase, such as polychlorobiphenylols (PCBs). During pregnancy, the placenta is an important source of estrogen, which is needed for normal fetal development and successful parturition (childbirth), and estrogen sulfotransferase is thought to play an important role in regulation of estrogen availability. Estrogen is a key hormone during pregnancy and controls the way a baby develops many key organs like the brain. Triclosan was found to be a very potent inhibitor of both estradiol and estrone sulfonation. The […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[155,30],"tags":[],"class_list":["post-4509","post","type-post","status-publish","format-standard","hentry","category-antibacterial","category-triclosan"],"yoast_head":"\nTriclosan Exposure Raises Pregnancy Concerns - Beyond Pesticides Daily News Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2010\/11\/triclosan-exposure-raises-pregnancy-concerns\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Triclosan Exposure Raises Pregnancy Concerns - Beyond Pesticides Daily News Blog\" \/>\n<meta property=\"og:description\" content=\"(Beyond Pesticides, November 10, 2010) A University of Florida, Gainesville study reports that the antibacterial pesticide triclosan, found in toothpaste, soaps, toys and clothing, interferes with estrogen metabolism in women and can disrupt a vital enzyme during pregnancy. 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The founders, who established Beyond Pesticides (originally as National Coalition Against the Misuse of Pesticides) as a nonprofit membership organization in 1981, felt that without the existence of such an organized, national network, local, state and national pesticide policy would become, under chemical industry pressure, increasingly unresponsive to public health and environmental concerns. Beyond Pesticides believes that people must have a voice in decisions that affect them directly. We believe decisions should not be made for us by chemical companies or by decision-makers who either do not have all of the facts or refuse to consider them. Learn more about our work, read A Year in Review\u20142021, our accomplishments are your victories! Beyond Pesticides seeks to protect healthy air, water, land, and food for ourselves and future generations. By forging ties with governments, nonprofits, and people who rely on these natural resources, we reduce the need for unnecessary pesticide use and protect public health and the environment. Beyond Pesticides provides hands-on services to the public and supports local action by: identifying and interpreting hazards; and, designing safe pest management programs. With the information provided by Beyond Pesticides, people may not only be able to make informed choices and adopt practices that protect themselves and their families from unnecessary exposure to pesticides, but they will be able to effect changes on community-wide pest management decisions and policies that govern pesticide use, such as pesticide uses in parks, schools, for community insect control and along roadsides. 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