{"id":618,"date":"2008-09-19T07:26:03","date_gmt":"2008-09-19T11:26:03","guid":{"rendered":"https:\/\/www.beyondpesticides.org\/dailynewsblog\/?p=618"},"modified":"2008-09-19T07:29:51","modified_gmt":"2008-09-19T11:29:51","slug":"more-research-links-pesticides-to-parkinson%e2%80%99s-disease","status":"publish","type":"post","link":"https:\/\/beyondpesticides.org\/dailynewsblog\/2008\/09\/more-research-links-pesticides-to-parkinson%e2%80%99s-disease\/","title":{"rendered":"More Research Links Pesticides to Parkinson\u2019s Disease"},"content":{"rendered":"

(Beyond Pesticides<\/em>, September 19, 2008) Adding to the body of epidemiologic evidence linking pesticides to Parkinson’s Disease (PD)<\/a>, a recent study shows a correlation between 100 PD patients and the use of the pesticide rotenone. The study was conducted by physicians and researchers at The University of Texas Health Science Center at Tyler (UTHSCT) and an East Texas Medical Center physician.The study\u2019s lead author is Aman Dhillon, MD, MS, assistant professor of occupational and environmental medicine at UTHSCT.<\/p>\n

Rotenone is highly toxic to fish and insects, but mildly toxic to warm-blooded animals and humans. It is made from the roots of tropical plants and is used in home gardens and in fisheries management to remove unwanted fish species, said Jeffrey Levin, MD, MSPH, chair of UTHSCT\u2019s Department of Occupational Health Sciences. Dr. Levin is a co-author of the study, published recently in the peer-reviewed Journal of Agromedicine<\/em>.<\/p>\n

A total of 184 people participated in the study: 100 had Parkinson\u2019s disease and 84 did not, though they had other neurological disorders. All were patients of George M. Plotkin, MD, Ph.D., a neurologist with a special interest in Parkinson\u2019s disease. Dr. Plotkin, medical director of the ETMC Movement Disorder Center, treats about 800 patients with Parkinson\u2019s disease. He is a co-author of the study and also a clinical associate professor in UTHSCT\u2019s Department of Occupational Health Sciences. \u201cIn this study, people with Parkinson\u2019s disease were 10 times more likely to have used rotenone than individuals in the control group,\u201d Dr. Levin said.<\/p>\n

Parkinson\u2019s is a neurodegenerative syndrome, affecting over 1.5 million people nationally, Dr. Plotkin said. There\u2019s a higher incidence of Parkinson\u2019s in certain industries, including farming and petroleum. Because Parkinson\u2019s was first described at the peak of the Industrial Revolution, there has always been a suspicion that it is an \u201cindustrial disease,\u201d reflecting the exposure history of those who contract it, he added.<\/p>\n

\u201cWhile epidemiologists have looked at a number of areas in the United States, this study is the first detailed account of exposure history in Parkinson\u2019s patients, in East Texas, as compared with age-matched controls,\u201d Dr. Plotkin said.<\/p>\n

\u201cThe results are rather striking, and reflect our notion that environmental agents may well affect individuals predisposed to developing the disease. Future research will need to focus on determining how this happens, with the hope that more careful management of hazardous materials will reduce the chances of Parkinson\u2019s disease developing in persons at risk,\u201d he said.<\/p>\n

Dr. Plotkin\u2019s patients completed a 17-page questionnaire designed by study investigators about their everyday life, work history, and habits, as well as their current and past use of various pesticides. Each individual in the study was at least 50 years old and had lived in Northeast Texas for at least five years. If they had Parkinson\u2019s, they had first been diagnosed with it at least five years ago.<\/p>\n

Though pesticide use has been linked to Parkinson\u2019s disease, this is one of the first studies to show a possible correlation between a specific pesticide \u2014 rotenone \u2014 and Parkinson\u2019s disease in humans, Dr. Dhillon said. The study also revealed a weaker link between other pesticides and Parkinson\u2019s disease. For example, people with Parkinson\u2019s disease were twice as likely to have used pesticides with chlorpyrifos<\/a>, such as Dursban, than individuals in the control group. Dursban and similar pesticides were banned by the U.S. Environmental Protection Agency in 2000 because of their potential to harm the developing brain and nervous system in children.<\/p>\n

\u201cIt seems to be a combination of genes and environment that causes the development of Parkinson\u2019s disease. This study examined one of many factors that may cause Parkinson\u2019s,\u201d Dr. Levin said. \u201cPart of the role of public health is to identify the risk factors for disease. If we can identify them, then people can avoid risk factors such as rotenone and hopefully prevent the disease.”<\/p>\n

Rotenone has been the subject of some debate before, including its use as a piscicide<\/a> in California and being linked in previous studies<\/a> to Parkinson’s. It is also toxic to nontarget species and further research could tie it more closely with Parkinson’s than it already is.<\/p>\n

\u201cThe next step is to verify the results of this study. We think there\u2019s potential to do a broader study examining more risk factors, with more individuals,\u201d Dr. Levin said.<\/p>\n","protected":false},"excerpt":{"rendered":"

(Beyond Pesticides, September 19, 2008) Adding to the body of epidemiologic evidence linking pesticides to Parkinson’s Disease (PD), a recent study shows a correlation between 100 PD patients and the use of the pesticide rotenone. The study was conducted by physicians and researchers at The University of Texas Health Science Center at Tyler (UTHSCT) and an East Texas Medical Center physician.The study\u2019s lead author is Aman Dhillon, MD, MS, assistant professor of occupational and environmental medicine at UTHSCT. Rotenone is highly toxic to fish and insects, but mildly toxic to warm-blooded animals and humans. It is made from the roots of tropical plants and is used in home gardens and in fisheries management to remove unwanted fish species, said Jeffrey Levin, MD, MSPH, chair of UTHSCT\u2019s Department of Occupational Health Sciences. Dr. Levin is a co-author of the study, published recently in the peer-reviewed Journal of Agromedicine. A total of 184 people participated in the study: 100 had Parkinson\u2019s disease and 84 did not, though they had other neurological disorders. All were patients of George M. Plotkin, MD, Ph.D., a neurologist with a special interest in Parkinson\u2019s disease. Dr. Plotkin, medical director of the ETMC Movement Disorder Center, treats about […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[145,37,189],"tags":[],"class_list":["post-618","post","type-post","status-publish","format-standard","hentry","category-parkinsons","category-rotenone","category-texas"],"yoast_head":"\nMore Research Links Pesticides to Parkinson\u2019s Disease - Beyond Pesticides Daily News Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2008\/09\/more-research-links-pesticides-to-parkinson\u2019s-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"More Research Links Pesticides to Parkinson\u2019s Disease - Beyond Pesticides Daily News Blog\" \/>\n<meta property=\"og:description\" content=\"(Beyond Pesticides, September 19, 2008) Adding to the body of epidemiologic evidence linking pesticides to Parkinson’s Disease (PD), a recent study shows a correlation between 100 PD patients and the use of the pesticide rotenone. The study was conducted by physicians and researchers at The University of Texas Health Science Center at Tyler (UTHSCT) and an East Texas Medical Center physician.The study\u2019s lead author is Aman Dhillon, MD, MS, assistant professor of occupational and environmental medicine at UTHSCT. Rotenone is highly toxic to fish and insects, but mildly toxic to warm-blooded animals and humans. It is made from the roots of tropical plants and is used in home gardens and in fisheries management to remove unwanted fish species, said Jeffrey Levin, MD, MSPH, chair of UTHSCT\u2019s Department of Occupational Health Sciences. Dr. Levin is a co-author of the study, published recently in the peer-reviewed Journal of Agromedicine. A total of 184 people participated in the study: 100 had Parkinson\u2019s disease and 84 did not, though they had other neurological disorders. All were patients of George M. Plotkin, MD, Ph.D., a neurologist with a special interest in Parkinson\u2019s disease. 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The founders, who established Beyond Pesticides (originally as National Coalition Against the Misuse of Pesticides) as a nonprofit membership organization in 1981, felt that without the existence of such an organized, national network, local, state and national pesticide policy would become, under chemical industry pressure, increasingly unresponsive to public health and environmental concerns. Beyond Pesticides believes that people must have a voice in decisions that affect them directly. We believe decisions should not be made for us by chemical companies or by decision-makers who either do not have all of the facts or refuse to consider them. Learn more about our work, read A Year in Review\u20142021, our accomplishments are your victories! Beyond Pesticides seeks to protect healthy air, water, land, and food for ourselves and future generations. By forging ties with governments, nonprofits, and people who rely on these natural resources, we reduce the need for unnecessary pesticide use and protect public health and the environment. Beyond Pesticides provides hands-on services to the public and supports local action by: identifying and interpreting hazards; and, designing safe pest management programs. With the information provided by Beyond Pesticides, people may not only be able to make informed choices and adopt practices that protect themselves and their families from unnecessary exposure to pesticides, but they will be able to effect changes on community-wide pest management decisions and policies that govern pesticide use, such as pesticide uses in parks, schools, for community insect control and along roadsides. 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