{"id":83,"date":"2007-04-24T07:14:19","date_gmt":"2007-04-24T11:14:19","guid":{"rendered":"https:\/\/www.beyondpesticides.org\/dailynewsblog\/?p=83"},"modified":"2007-12-11T10:46:18","modified_gmt":"2007-12-11T14:46:18","slug":"studies-strengthen-link-between-pesticides-and-parkinson%e2%80%99s","status":"publish","type":"post","link":"https:\/\/beyondpesticides.org\/dailynewsblog\/2007\/04\/studies-strengthen-link-between-pesticides-and-parkinson%e2%80%99s\/","title":{"rendered":"Studies Strengthen Link Between Pesticides and Parkinson\u2019s"},"content":{"rendered":"<p><font size=\"2\">(<em>Beyond Pesticides<\/em>, April 24, 2007) Three recent studies were presented earlier this month at the Parkinson\u2019s Disease Environmental Research meeting in California strengthening the theory that pesticides increase risk of the disease. The studies clarify how pesticide exposure can lead to the development of Parkinson\u2019s.<\/font><\/p>\n<p class=\"MsoNormal\"><font size=\"2\">Two pesticides named in the studies are <a target=\"_blank\" href=\"https:\/\/www.beyondpesticides.org\/pesticides\/factsheets\/Paraquat.pdf\">paraquat <\/a>and <a target=\"_blank\" href=\"https:\/\/www.beyondpesticides.org\/news\/daily_news_archive\/2006\/09_22_06.htm\">dieldrin<\/a>, both of which have been linked to Parkinson\u2019s in the past. The three new studies, however, combine information from human and animal studies to show how exposure can lead to onset of the disease. As William Langston, M.D., founder of the Parkinson\u2019s Institute, told Reuters, \u201cAll of these pieces really look like they are coming together now.&#8221;<\/font><\/p>\n<p class=\"MsoNormal\"><font size=\"2\">The <a target=\"_blank\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&#038;db=pubmed&#038;dopt=Abstract&#038;list_uids=17116648\">first study<\/a> examined a cohort of 80,000 licensed private pesticide applicators and spouses. Researchers found farm workers exposed to paraquat had twice the expected risk of Parkinson\u2019s.<\/font><\/p>\n<p class=\"MsoNormal\"><font size=\"2\">The <a target=\"_blank\" href=\"http:\/\/www.thepi.org\/altruesite\/files\/parkinson\/News\/Asilomar2007.pdf\">second and third studies<\/a> address a protein called alpha-synuclein. The second study shows the protein builds up in rodents exposed to paraquat. The third study connects this protein to Parkinson\u2019s by finding that the protein kills the dopamine-producing brain cells affected by the disease.<\/font><\/p>\n<p class=\"MsoNormal\"><font size=\"2\">One common difficulty in tracking pesticide-induced diseases is the amount of time that passes between exposure and the onset of disease. In these studies, pesticide exposure could be accurately tracked by records of pesticide purchase, details of which will be published later, according to Dr. Langston.<\/font><\/p>\n<p class=\"MsoNormal\"><font size=\"2\">The study of laboratory animals could be the missing link in proving causation of Parkinson\u2019s. Donato Di Monte, M.D., of the Parkinson\u2019s Institute, said of the protein buildup, \u201cThis increase in alpha-synuclein in the brain could be the missing link between the exposure to this agent and how this agent causes the disease.&#8221; In addition, Dr. Langston said brain inflammation during pesticide exposure greatly increased the risk of Parkinson\u2019s in later years, as \u201csystemic inflammation may somehow sensitize the brain.&#8221;<\/font><\/p>\n<p class=\"MsoNormal\"><font size=\"2\">These studies are only the latest linking pesticides, particularly paraquat, to Parkinson\u2019s disease. For previous Daily News stories on the subject (and other health effects), click <a target=\"_blank\" href=\"https:\/\/www.beyondpesticides.org\/news\/daily_news_archive\/index.htm#cancer\">here. <\/a><\/font><\/p>\n<p class=\"MsoNormal\"><font size=\"2\"><em>Source: <a target=\"_blank\" href=\"http:\/\/www.reuters.com\/article\/reutersEdge\/idUSN2222543520070423?src=042307_1032_DOUBLEFEATURE_&#038;pageNumber=1\">Reuters<\/a><\/em><a target=\"_blank\" href=\"http:\/\/www.reuters.com\/article\/reutersEdge\/idUSN2222543520070423?src=042307_1032_DOUBLEFEATURE_&#038;pageNumber=1\"> <\/a><\/font><\/p>\n","protected":false},"excerpt":{"rendered":"<p>(Beyond Pesticides, April 24, 2007) Three recent studies were presented earlier this month at the Parkinson\u2019s Disease Environmental Research meeting in California strengthening the theory that pesticides increase risk of the disease. The studies clarify how pesticide exposure can lead to the development of Parkinson\u2019s. Two pesticides named in the studies are paraquat and dieldrin, both of which have been linked to Parkinson\u2019s in the past. The three new studies, however, combine information from human and animal studies to show how exposure can lead to onset of the disease. As William Langston, M.D., founder of the Parkinson\u2019s Institute, told Reuters, \u201cAll of these pieces really look like they are coming together now.&#8221; The first study examined a cohort of 80,000 licensed private pesticide applicators and spouses. Researchers found farm workers exposed to paraquat had twice the expected risk of Parkinson\u2019s. The second and third studies address a protein called alpha-synuclein. The second study shows the protein builds up in rodents exposed to paraquat. The third study connects this protein to Parkinson\u2019s by finding that the protein kills the dopamine-producing brain cells affected by the disease. One common difficulty in tracking pesticide-induced diseases is the amount of time that passes between [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27,3,35],"tags":[],"class_list":["post-83","post","type-post","status-publish","format-standard","hentry","category-dieldrin","category-diseasehealth-effects","category-paraquat"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Studies Strengthen Link Between Pesticides and Parkinson\u2019s - Beyond Pesticides Daily News Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2007\/04\/studies-strengthen-link-between-pesticides-and-parkinson\u2019s\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Studies Strengthen Link Between Pesticides and Parkinson\u2019s - Beyond Pesticides Daily News Blog\" \/>\n<meta property=\"og:description\" content=\"(Beyond Pesticides, April 24, 2007) Three recent studies were presented earlier this month at the Parkinson\u2019s Disease Environmental Research meeting in California strengthening the theory that pesticides increase risk of the disease. The studies clarify how pesticide exposure can lead to the development of Parkinson\u2019s. Two pesticides named in the studies are paraquat and dieldrin, both of which have been linked to Parkinson\u2019s in the past. The three new studies, however, combine information from human and animal studies to show how exposure can lead to onset of the disease. As William Langston, M.D., founder of the Parkinson\u2019s Institute, told Reuters, \u201cAll of these pieces really look like they are coming together now.&#8221; The first study examined a cohort of 80,000 licensed private pesticide applicators and spouses. Researchers found farm workers exposed to paraquat had twice the expected risk of Parkinson\u2019s. The second and third studies address a protein called alpha-synuclein. The second study shows the protein builds up in rodents exposed to paraquat. The third study connects this protein to Parkinson\u2019s by finding that the protein kills the dopamine-producing brain cells affected by the disease. 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The studies clarify how pesticide exposure can lead to the development of Parkinson\u2019s. Two pesticides named in the studies are paraquat and dieldrin, both of which have been linked to Parkinson\u2019s in the past. The three new studies, however, combine information from human and animal studies to show how exposure can lead to onset of the disease. As William Langston, M.D., founder of the Parkinson\u2019s Institute, told Reuters, \u201cAll of these pieces really look like they are coming together now.&#8221; The first study examined a cohort of 80,000 licensed private pesticide applicators and spouses. Researchers found farm workers exposed to paraquat had twice the expected risk of Parkinson\u2019s. The second and third studies address a protein called alpha-synuclein. The second study shows the protein builds up in rodents exposed to paraquat. 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