{"id":912,"date":"2008-11-17T10:58:43","date_gmt":"2008-11-17T14:58:43","guid":{"rendered":"https:\/\/www.beyondpesticides.org\/dailynewsblog\/?p=912"},"modified":"2025-03-02T12:49:29","modified_gmt":"2025-03-02T17:49:29","slug":"study-finds-low-pesticide-concentrations-can-become-toxic-mixture","status":"publish","type":"post","link":"https:\/\/beyondpesticides.org\/dailynewsblog\/2008\/11\/study-finds-low-pesticide-concentrations-can-become-toxic-mixture\/","title":{"rendered":"Study Finds Low Pesticide Concentrations Can Become Toxic Mixture"},"content":{"rendered":"<p><span style=\"font-size: small;\">(<em>Beyond Pesticides<\/em>, November 17, 2008) A toxic soup of the most commonly used pesticides frequently detected in nature can adversely affect the environment and decimate amphibian populations even if the concentration of the individual chemicals are within limits considered safe, according to University of Pittsburgh research published in the online edition of <a href=\"https:\/\/www.biology.pitt.edu\/sites\/default\/files\/facilities-images\/3156.pdf\"><em>Oecologia<\/em><\/a>. <\/span><\/p>\n<p>The results of this study build on a nine-year effort to understand potential links between the global decline in amphibians, routine pesticide use, and the possible threat to humans in the future. Amphibians are considered an environmental indicator species because of their unique sensitivity to pollutants. Their demise from pesticide exposure could foreshadow the fate of less sensitive animals, according to study author Dr. Rick Relyea, Ph.D., an associate professor of biological sciences in the University of Pittsburgh\u2019s School of Arts and Sciences. Leopard frogs, in particular, are vulnerable to contamination; once plentiful across North America, their population has declined in recent years as pollution and deforestation has increased.<\/p>\n<p>Dr. Relyea exposed gray tree frog and leopard frog tadpoles to small amounts of the ten pesticides that are widely used throughout the world. Dr. Relyea selected five insecticides: <a href=\"https:\/\/www.beyondpesticides.org\/gateway\/pesticide\/carbaryl.htm\">carbaryl<\/a>, <a href=\"https:\/\/www.beyondpesticides.org\/gateway\/pesticide\/chlorpyrifos.htm\">chlorpyrifos<\/a>, <a href=\"https:\/\/www.beyondpesticides.org\/gateway\/pesticide\/diazinon.htm\">diazinon<\/a>, <a href=\"https:\/\/www.beyondpesticides.org\/gateway\/pesticide\/endosulfan.htm\">endosulfan<\/a>, and <a href=\"https:\/\/www.beyondpesticides.org\/gateway\/pesticide\/malathion.htm\">malathion<\/a>; and five herbicides: <a href=\"https:\/\/www.beyondpesticides.org\/dailynewsblog\/index.php?s=acetochlor\">acetochlor<\/a>, <a href=\"https:\/\/www.beyondpesticides.org\/gateway\/pesticide\/atrazine.htm\">atrazine<\/a>, <a href=\"https:\/\/www.beyondpesticides.org\/gateway\/pesticide\/glyphosate.htm\">glyphosate<\/a>, <a href=\"https:\/\/www.beyondpesticides.org\/dailynewsblog\/index.php?s=metolachlor\">metolachlor<\/a>, and <a href=\"https:\/\/www.beyondpesticides.org\/gateway\/pesticide\/24d.htm\">2,4-D<\/a>. He administered the following doses: each of the pesticides alone, the insecticides combined, a mix of the five herbicides, or all 10 of the poisons.<\/p>\n<p>Dr. Relyea found that a mixture of all 10 chemicals killed 99 percent of leopard frog tadpoles as did the insecticide-only mixture; the herbicide mixture had no effect on the tadpoles. While leopard frogs perished, gray tree frogs did not succumb to the poisons and instead flourished in the absence of leopard frog competitors. Dr. Relyea also discovered that endosulfan, a neurotoxin banned in several nations but still used extensively in U.S. agriculture, is inordinately deadly to leopard frog tadpoles. By itself, the chemical caused 84 percent of the leopard frogs to die. This lethality was previously unknown because current regulations from the U.S. Environmental Protection Agency (EPA) do not require amphibian testing. His results show that endosulfan was not only highly toxic to leopard frogs, but also that it served as the key ingredient of the pesticide mixture that eliminated the bulk of leopard frog tadpoles.<\/p>\n<p>\u201cEndosulfan appears to be about 1,000-times more lethal to amphibians than other pesticides that we have examined,\u201d Dr. Relyea said. \u201cUnfortunately, pesticide regulations do not require amphibian testing, so very little is known about endosulfan&#8217;s impact on amphibians, despite being sprayed in the environment for more than five decades.\u201d<\/p>\n<p>For most of the pesticides, the concentration administered (2 to 16 parts per billion) was far below the human-lifetime-exposure levels set by the EPA and also falls short of the maximum concentrations detected in natural bodies of water. But the research suggests that these low concentrations, which can travel easily by water and wind, can combine into one toxic mixture. The study points out that declining amphibian populations have been recorded in pristine areas far downwind from areas of active pesticide use, and he suggests that the chemical cocktail he describes could be a culprit.<\/p>\n<p>Dr. Relyea published a study in the Oct. 1, 2008 edition of <a href=\"https:\/\/www.beyondpesticides.org\/dailynewsblog\/?p=714\"><em>Ecological Applications<\/em><\/a> reporting that gradual amounts of malathion, the most popular insecticide in the United States, that were too small to directly kill developing leopard frog tadpoles instead sparked a biological chain of events that deprived them of their primary food source. As a result, nearly half the tadpoles in the experiment did not reach maturity and would have died in nature. Dr. Relyea has published <a href=\"http:\/\/www.pitt.edu\/~biohome\/Dept\/Frame\/Faculty\/relyeaabstract.htm#3156%20\">a number of papers<\/a> on the effects of pesticides on amphibians and aquatic communities, including <a href=\"http:\/\/www.pitt.edu\/~biohome\/Dept\/pdf\/1703.pdf\">a 2005 study<\/a> suggesting that the popular weed-killer Roundup \u00ae (active ingredient glyphosate) is \u201cextremely lethal\u201d to amphibians in concentrations found in the environment.<\/p>\n<p>See Beyond Pesticides\u2019 <a href=\"https:\/\/www.beyondpesticides.org\/dailynewsblog\/index.php?s=frog%20\">Daily News Blog<\/a> for additional news stories on pesticides\u2019 impact on frogs.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>(Beyond Pesticides, November 17, 2008) A toxic soup of the most commonly used pesticides frequently detected in nature can adversely affect the environment and decimate amphibian populations even if the concentration of the individual chemicals are within limits considered safe, according to University of Pittsburgh research published in the online edition of Oecologia. The results of this study build on a nine-year effort to understand potential links between the global decline in amphibians, routine pesticide use, and the possible threat to humans in the future. Amphibians are considered an environmental indicator species because of their unique sensitivity to pollutants. Their demise from pesticide exposure could foreshadow the fate of less sensitive animals, according to study author Dr. Rick Relyea, Ph.D., an associate professor of biological sciences in the University of Pittsburgh\u2019s School of Arts and Sciences. Leopard frogs, in particular, are vulnerable to contamination; once plentiful across North America, their population has declined in recent years as pollution and deforestation has increased. Dr. Relyea exposed gray tree frog and leopard frog tadpoles to small amounts of the ten pesticides that are widely used throughout the world. Dr. Relyea selected five insecticides: carbaryl, chlorpyrifos, diazinon, endosulfan, and malathion; and five herbicides: [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[89,126,72,51,33,131,23,41,105,201,12,13],"tags":[],"class_list":["post-912","post","type-post","status-publish","format-standard","hentry","category-24-d","category-acetochlor","category-atrazine","category-carbaryl","category-chlorpyrifos","category-diazinon","category-endosulfan","category-glyphosate","category-malathion","category-metolachlor","category-water","category-wildlifeenvironment"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Study Finds Low Pesticide Concentrations Can Become Toxic Mixture - Beyond Pesticides Daily News Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/beyondpesticides.org\/dailynewsblog\/2008\/11\/study-finds-low-pesticide-concentrations-can-become-toxic-mixture\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study Finds Low Pesticide Concentrations Can Become Toxic Mixture - Beyond Pesticides Daily News Blog\" \/>\n<meta property=\"og:description\" content=\"(Beyond Pesticides, November 17, 2008) A toxic soup of the most commonly used pesticides frequently detected in nature can adversely affect the environment and decimate amphibian populations even if the concentration of the individual chemicals are within limits considered safe, according to University of Pittsburgh research published in the online edition of Oecologia. The results of this study build on a nine-year effort to understand potential links between the global decline in amphibians, routine pesticide use, and the possible threat to humans in the future. Amphibians are considered an environmental indicator species because of their unique sensitivity to pollutants. Their demise from pesticide exposure could foreshadow the fate of less sensitive animals, according to study author Dr. Rick Relyea, Ph.D., an associate professor of biological sciences in the University of Pittsburgh\u2019s School of Arts and Sciences. Leopard frogs, in particular, are vulnerable to contamination; once plentiful across North America, their population has declined in recent years as pollution and deforestation has increased. Dr. Relyea exposed gray tree frog and leopard frog tadpoles to small amounts of the ten pesticides that are widely used throughout the world. 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The founders, who established Beyond Pesticides (originally as National Coalition Against the Misuse of Pesticides) as a nonprofit membership organization in 1981, felt that without the existence of such an organized, national network, local, state and national pesticide policy would become, under chemical industry pressure, increasingly unresponsive to public health and environmental concerns. Beyond Pesticides believes that people must have a voice in decisions that affect them directly. We believe decisions should not be made for us by chemical companies or by decision-makers who either do not have all of the facts or refuse to consider them. Learn more about our work, read A Year in Review\u20142021, our accomplishments are your victories! Beyond Pesticides seeks to protect healthy air, water, land, and food for ourselves and future generations. By forging ties with governments, nonprofits, and people who rely on these natural resources, we reduce the need for unnecessary pesticide use and protect public health and the environment. Beyond Pesticides provides hands-on services to the public and supports local action by: identifying and interpreting hazards; and, designing safe pest management programs. With the information provided by Beyond Pesticides, people may not only be able to make informed choices and adopt practices that protect themselves and their families from unnecessary exposure to pesticides, but they will be able to effect changes on community-wide pest management decisions and policies that govern pesticide use, such as pesticide uses in parks, schools, for community insect control and along roadsides. 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The results of this study build on a nine-year effort to understand potential links between the global decline in amphibians, routine pesticide use, and the possible threat to humans in the future. Amphibians are considered an environmental indicator species because of their unique sensitivity to pollutants. Their demise from pesticide exposure could foreshadow the fate of less sensitive animals, according to study author Dr. Rick Relyea, Ph.D., an associate professor of biological sciences in the University of Pittsburgh\u2019s School of Arts and Sciences. Leopard frogs, in particular, are vulnerable to contamination; once plentiful across North America, their population has declined in recent years as pollution and deforestation has increased. Dr. Relyea exposed gray tree frog and leopard frog tadpoles to small amounts of the ten pesticides that are widely used throughout the world. Dr. Relyea selected five insecticides: carbaryl, chlorpyrifos, diazinon, endosulfan, and malathion; and five herbicides: [&hellip;]","og_url":"https:\/\/beyondpesticides.org\/dailynewsblog\/2008\/11\/study-finds-low-pesticide-concentrations-can-become-toxic-mixture\/","og_site_name":"Beyond Pesticides Daily News Blog","article_publisher":"https:\/\/www.facebook.com\/beyondpesticides","article_author":"https:\/\/www.facebook.com\/beyondpesticides\/","article_published_time":"2008-11-17T14:58:43+00:00","article_modified_time":"2025-03-02T17:49:29+00:00","author":"Beyond Pesticides","twitter_card":"summary_large_image","twitter_creator":"@ByondPesticides","twitter_site":"@ByondPesticides","twitter_misc":{"Written by":"Beyond Pesticides","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2008\/11\/study-finds-low-pesticide-concentrations-can-become-toxic-mixture\/#article","isPartOf":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2008\/11\/study-finds-low-pesticide-concentrations-can-become-toxic-mixture\/"},"author":{"name":"Beyond Pesticides","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#\/schema\/person\/1b5c0a0981b549cc5b628770073031f4"},"headline":"Study Finds Low Pesticide Concentrations Can Become Toxic Mixture","datePublished":"2008-11-17T14:58:43+00:00","dateModified":"2025-03-02T17:49:29+00:00","mainEntityOfPage":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2008\/11\/study-finds-low-pesticide-concentrations-can-become-toxic-mixture\/"},"wordCount":656,"commentCount":0,"publisher":{"@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/#organization"},"articleSection":["2,4-D","Acetochlor","Atrazine","Carbaryl","Chlorpyrifos","Diazinon","Endosulfan","Glyphosate","Malathion","Metolachlor","Water","Wildlife\/Endangered Sp."],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/beyondpesticides.org\/dailynewsblog\/2008\/11\/study-finds-low-pesticide-concentrations-can-become-toxic-mixture\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/beyondpesticides.org\/dailynewsblog\/2008\/11\/study-finds-low-pesticide-concentrations-can-become-toxic-mixture\/","url":"https:\/\/beyondpesticides.org\/dailynewsblog\/2008\/11\/study-finds-low-pesticide-concentrations-can-become-toxic-mixture\/","name":"Study Finds Low Pesticide Concentrations Can Become Toxic Mixture - 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