Gateway on Pesticide Hazards and Safe Pest Management

Beyond Pesticides offers resources below to evaluate the health and ecological effects of specific chemical exposure from ACTIVE INGREDIENTS in pesticide products, as well as regulatory information and supporting scientific documents. Because various pesticide products can contain more than one active ingredient, it is important to READ the LABEL to determine chemical components.

With 192 different active ingredients and counting, it is essential to establish the connection between the use of these chemicals and their respective hazards.

View the step-by-step guide on how to search for the active ingredient(s) in pesticide products below:

1. Go to U.S. EPA's Pesticide Product and Label System and enter the product name. The generic product name may vary.
   
2. After searching, click on the chemical ingredients tab or the link for the most recent label to find Active Ingredients.
                Chemical List                                            Label List 
   
   If one selects the chemical ingredients tab, skip to Step 4 . If not, proceed to step number 3
   
   
3. To find the active ingredient(s) on the label, search for the page in the document containing the date of registration. Usually, the active ingredients section occurs within the first few pages of the label document.
   
   
4. Return to the Beyond Pesticides Gateway and search for the active ingredient name in the yellow box to the right or from the list below. 
   
   

Vinclozolin

General Information

• Product Names:
  Ronilan (BASF)
  Curalan (BASF)

• Chemical Class: Morpholine fungicide
• Uses: Canola and imported grapes
• Alternatives: Organic agriculture
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Possible (8)
• Endocrine Disruption: Yes (30, 36)
• Reproductive Effects: Yes (8)
• Neurotoxicity: Not documented
• Kidney/Liver Damage: Not documented
• Sensitizer/ Irritant: Yes (8)
• Birth/Developmental: Not documented
• Detected in Groundwater: Not documented
• Potential Leacher: Not documented
• Toxic to Birds: Not documented
• Toxic to Fish/Aquatic Organisms: Yes (8)
• Toxic to Bees: Not documented

Residential Uses as Found in the ManageSafe™ Database

• Mold

Additional Information

• Regulatory Status:
  • RED signed 10/2000
• Supporting information:
  • PAN Pesticides Database: Vinclozolin (Pesticide Action Network)
• Studies:
• Effects of processing on pesticide residues in peaches intended for baby food.. Balinova AM, Mladenova RI, Shtereva DD. 2006. Food Addit Contam.23(9):895-901
• Environmental antiandrogens: low doses of the fungicide vinclozolin alter sexual differentiation of the male rat.. Gray LE, et al. 1999. Toxicol Ind Health;15(1-2):48-64
• Effects of the endocrine disruptor vinclozolin in male reproduction: a systematic review and meta-analysis. Feijó, M., Martins, R.V., Socorro, S., Pereira, L. and Correia, S., 2021. Biology of Reproduction.
• Environmentally induced epigenetic transgenerational inheritance of altered Sertoli cell transcriptome and epigenome: molecular etiology of male infertility.. Guerrero-Bosagna C, Savenkova M, Haque MM, et al. 2013. PLoS One. 8(3):e59922
• Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility. Anway, M.D. et al. 2005. Science: 308(5727) pp. 1466 - 1469
• Exploring associations between residential exposure to pesticides and birth outcomes using the Dutch birth registry. Simões, M., Vermeulen, R., Portengen, L., Janssen, N. and Huss, A., 2023. Environment International, p.108085.