Gateway on Pesticide Hazards and Safe Pest Management

Beyond Pesticides offers resources below to evaluate the health and ecological effects of specific chemical exposure from ACTIVE INGREDIENTS in pesticide products, as well as regulatory information and supporting scientific documents. Because various pesticide products can contain more than one active ingredient, it is important to READ the LABEL to determine chemical components.

With 192 different active ingredients and counting, it is essential to establish the connection between the use of these chemicals and their respective hazards.

View the step-by-step guide on how to search for the active ingredient(s) in pesticide products below:

1. Go to U.S. EPA's Pesticide Product and Label System and enter the product name. The generic product name may vary.
   
2. After searching, click on the chemical ingredients tab or the link for the most recent label to find Active Ingredients.
                Chemical List                                            Label List 
   
   If one selects the chemical ingredients tab, skip to Step 4 . If not, proceed to step number 3
   
   
3. To find the active ingredient(s) on the label, search for the page in the document containing the date of registration. Usually, the active ingredients section occurs within the first few pages of the label document.
   
   
4. Return to the Beyond Pesticides Gateway and search for the active ingredient name in the yellow box to the right or from the list below. 
   
   

Indaziflam

General Information

• Fact Sheet: Indaziflam Fact Sheet.pdf
• Product Names:

  Lawn 3FL Herbicide Concentrate/Ready-to-spray 
  SPECTICLE PLUS TURF FERTILIZER HERBICIDE 
  ESPLANADE
  NS Herbicide Concentrate
  

• Chemical Class: Fluoroalkyltriazine herbicide
• Uses: Uses on residential and commercial areas (lawns, ornamentals, etc.), turf, field grown ornamentals and Christmas trees, commercial nursery and landscape plantings, and forestry sites.
• Alternatives: Ogranic land care
• Beyond Pesticides rating: Toxic

Health and Environmental Effects

• Cancer: Not documented
• Endocrine Disruption: Yes (8)
• Reproductive Effects: Not documented
• Neurotoxicity: Yes (8)
• Kidney/Liver Damage: Yes (8)
• Sensitizer/ Irritant: Not documented
• Birth/Developmental: Yes (8)
• Detected in Groundwater: Not documented
• Potential Leacher: Yes (8)
• Toxic to Birds: Not documented
• Toxic to Fish/Aquatic Organisms: Yes (8)
• Toxic to Bees: Not documented

Additional Information

• Regulatory Status:
  • EPA factsheet (2010)
• Supporting information:
  • USDA Human Health and Ecological Risk Assessment (HHERA) for Indaziflam (2020)
• Studies:
• The silence of the clams: Forestry registered pesticides as multiple stressors on soft-shell clams. Tissot, A.G., Granek, E.F., Thompson, A.W., Hladik, M.L., Moran, P.W. and Scully-Engelmeyer, K. Science of The Total Environment, p.152053.
• The possible cytotoxicity and genotoxicity assessment of indaziflam on HepG2 cells. Adıgüzel, S. (2023) The possible cytotoxicity and genotoxicity assessment of indaziflam on HepG2 cells, Human & Experimental Toxicology. Available at: https://journals.sagepub.com/doi/full/10.1177/09603271231183145.
• Mobility, Degradation, and Uptake of Indaziflam under Greenhouse Conditions. González-Delgado, A.M. and Shukla, M.K. (2020) Mobility, degradation, and uptake of Indaziflam under greenhouse conditions, HortScience. Available at: https://journals.ashs.org/hortsci/view/journals/hortsci/55/8/article-p1216.xml.