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Daily News Blog

Archive for the 'Disease/Health Effects' Category


19
May

European Union Plans to Propose a 10-year Extension for the Approval of Glyphosate Use

(Beyond Pesticides, May 19, 2017) In spite of a growing body of evidence implicating glyphosate in a wide range of human illnesses and environmental impacts, the European Union (EU) plans to propose a 10-year extension for the approval of glyphosate use. Previously, the European Commission (the Commission), which is in charge of the approval, was forced to issue a limited license extension for the chemical because member states could not reach a consensus. The Commission was holding out for further information on carcinogenicity, which was assessed by the European Chemicals Agency (ECHA), and whose report was issued in March 2017. According to ECHA’s assessment, glyphosate is not carcinogenic. Glyphosate is the active ingredient in Monsanto’s Roundup brand of weed-killers, and research by the World Health Organization’s International Agency for Research on Cancer (IARC) has found that it is a probable human carcinogen. Since IARC’s findings were released, Monsanto has made several efforts to discredit the research of this well respected, international body, including attempting to influence government agencies. According to a Bloomberg BNA article, “The commission will discuss with EU member nations the prospect of a 10-year reauthorization, said Anca Paduraru, spokeswoman for the commission.” Once the Commission proposes the […]

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12
May

Exposure to Heavy Pesticide Use Can Impact Neurobehavioral Performance in Children

(Beyond Pesticides, May 12, 2017) Researchers from the University of California San Diego, School of Medicine, in collaboration with scientists from Ecuador and Minnesota, have found that exposure to heavy pesticide use during peak periods can impact neurobehavioral performance in children. The study focused on exposure to organophosphate pesticides, which have been associated with a broad range of diseases in both children and adults. The study, published in NeuroToxicology, involved 308 non-worker Ecuadorian children between the ages of 4 and 9. Neurobehavioral performance for each child was tested once between 63 and 100 days after the Mother’s Day flower harvest, which is a period of high pesticide use in Ecuador. The researchers found that children examined sooner after Mother’s Day had lower scores than children who were tested later. “Children examined sooner after the flower harvest displayed lower performance on most measures, such as attention, self-control, visuospatial processing (the ability to perceive and interact with our visual world) and sensorimotor (eye-hand coordination) compared to children examined later in a time of lower flower production and pesticide use,” said Jose R. Suarez-Lopez, MD, PhD, and lead author of the study, to ScienceBlog. Dr. Suarez-Lopez continued, “This discovery is novel because it […]

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09
May

San Juan Capistrano, CA Passes Organic Landscape Policy for City Lands

(Beyond Pesticides, May 9, 2017) Last month, San Juan Capistrano (SJC) became the latest community in Orange County, CA to pass an organic landscaping policy for city parks and open spaces. The city’s move follows the passage of an organic land care policy in nearby Irvine, CA last year, and like Irvine, was brought forward by a strong contingent of local advocates, health practitioners, and city officials working together to safeguard public health and the environment. By a vote of 4-0-1, San Juan Capistrano’s City Council put the community on the cutting edge of local changes to pesticide use that are taking place across the country. SJC’s policy is the result of persistent pressure and engagement by community group Non-Toxic San Juan Capistrano with city officials. A change.org petition hosted by the group, which received over 300 signatures, detailed the discussions and responses the group received from local leaders. At the time the City Council took up the issue at a mid-April meeting, Mayor Kerry Ferguson made a strong statement indicating that, “Chemical pesticides and herbicides have been proven to be toxic to children, pets, and the general public.” Mayor Ferguson further said, “While [chemical pesticide] use is somewhat limited […]

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27
Apr

Chemical Companies Knowingly Allowed Carcinogenic Contaminant in Common Pesticide

(Beyond Pesticides, April 27, 2017) Multinational chemical companies Dow Chemical Company and Shell Chemical Company knowingly sold and marketed fumigants contaminated with a cancer-causing chemical that had a strong propensity to leach into and remain in groundwater, according to a recent report from the Environmental Working Group (EWG) and a lawsuit against the companies. The contaminant of concern, 1,2,3-trichloropropene (TCP), was a manufacturing by-product found in Dow’s Telone and Shell’s D-D fumigant pesticide products with the active ingredient 1,3-Dichloropropene. The products, used to kill soil-dwelling nematodes, are toxic in their own right, but contained TCP in their formulation from the 1940s until the mid-1980s. EWG’s report details widespread contamination of drinking water in California’s agricultural regions, with detections found in 562 wells, and 94 public water systems identifying TCP above legal limits. Thirty-seven additional public water systems serving nearly 4 million U.S. residents throughout the country were also found to contain TCP. The U.S. Environmental Protection Agency has never set maximum contaminant levels for TCP in drinking water, but requires public reporting above the infinitesimally small amount of 30 parts per trillion, roughly six times higher than what the state of California requires. However, even proposed limits of 5 parts per trillion […]

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11
Apr

Glyphosate Use Could be Linked to Pregnancy Problems

(Beyond Pesticides, April 11, 2017) New data presented last week at a children’s health conference show that glyphosate, the active ingredient in the popular Roundup weed killer, is detected in pregnant women and could lead to adverse pregnancy outcomes, including shorter gestation times and lower birth weights. The researchers here are calling for more biomonitoring of the presence of glyphosate in the public, in spite of industry and government efforts to undermine the science surrounding the human health impacts of the herbicide. Researchers tested and tracked 69 expectant mothers and found that the presence of glyphosate levels in their bodily fluids correlated with unfavorable birth outcomes. The research is still in preliminary stages and is a project of the Children’s Environmental Health Network (CEHN), which is studying the reproductive and children’s health impacts of rising herbicide use in the Midwest. The preliminary results were presented at CEHN’s conference last Thursday in Washington DC. Learn more about the project here. This is a huge issue,” said Paul Winchester, M.D., member of the research team involved with this study, medical director of the neonatal intensive care unit at the Franciscan St. Francis Health system and professor of clinical pediatrics at Riley Hospital for […]

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04
Apr

Pyrethroid Insecticides Cause Premature Puberty in Boys

(Beyond Pesticides, April 4, 2017) Exposure to commonly used pyrethroid insecticides results in the early onset of puberty in boys, according to a study presented at the 99th meeting of the Endocrine Society in Orlando, Florida this week. Pyrethroids, which exhibit endocrine disrupting properties, have the ability to interfere with the proper regulation of the human body’s hormonal system. This research is the first to investigate not only the association between pyrethroids and accelerated puberty, but also the causal mechanisms involved in the physiological changes taking place within the human body. For the study, Jing Liu, PhD, and colleagues from Zhejuang University in China, analyzed the urine in 463 Chinese boys aged 9 to 16 for the presence of metabolites from the pyrethroid insecticide cypermethrin. Results show that a 10% increase in the metabolite 3-PBA is associated with a roughly 4% increase in luteinizing and follicle-stimulating hormones, which facilitate puberty and sperm production. The author’s note that, “Boys with increased urinary levels of 3-PBA have a significantly increased risk of earlier pubertal onset, in which the odds of being in an advanced pubertal stage are increase by 73% to 110%.” The study, acknowledging the limitation in determining causality, further investigates the […]

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31
Mar

EPA Reverses Course and Allows Continued Use of Highly Neurotoxic Pesticide, Chlorpyrifos

(Beyond Pesticides, March 31, 2017) On Wednesday, Scott Pruitt, the new head of the Environmental Protection Agency (EPA), rejected the conclusions of EPA scientists, and independent scientific literature, and reversed a tentative decision from 2015 to revoke food residue tolerances of chlorpyrifos due to the chemical’s neurotoxic impacts. This would have effectively banned chlorpyrifos from agriculture. This decision stemmed from a petition and lawsuit filed by the Natural Resources Defense Council (NRDC) and Pesticide Action Network North America (PANNA)  ten years ago, calling for EPA to revoke all chlorpyrifos tolerances and cancel all registrations. A Federal Appeals court mandated that EPA take final action by March 31, 2017. Mr. Pruitt’s decision leaves the door open for continued neurotoxic dangers for humans, especially children, who have been shown to be especially vulnerable to chlorpyrifos. Chlorpyrifos is part of the organophosphate (OPs) class of pesticides, which were used in World War II as nerve agents. As potent neurotoxicants, organophosphates are extremely harmful to the nervous system, given that they are cholinesterase inhibitors and bind irreversibly to the active site of an enzyme essential for normal nerve impulse transmission. The scientific evidence of neurotoxic dangers associated with chlorpyrifos exposure is extensive and consistent. Epidemiological data also […]

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28
Mar

USDA Cancels Plans to Test for Glyphosate Residues in U.S. Food this Year

(Beyond Pesticides, March 28, 2017) The U.S. Department of Agriculture (USDA) has abandoned its plans to test the U.S. food supply for the presence of glyphosate residues, according to a story from veteran reporter Carrey Gillam in The Huffington Post. The decision comes amid heated controversy over the carcinogenicity of glyphosate, which was cleared by a California judge for listing under California’s Prop 65 earlier this year. The federal government’s pesticide monitoring program, which is run jointly by USDA, the Food and Drug Administration (FDA), and the Environmental Protection Agency (EPA), was criticized by the Government Accountability Office (GAO) in 2014 for its failure to test for the widely used herbicide. In early 2016, Beyond Pesticides met with EPA regulators to discuss testing for glyphosate residues in the U.S. food supply. At the time, officials said that FDA was testing honey, and USDA would be conducting more extensive food testing beginning in 2017. USDA had tested soybeans for glyphosate residue in 2011, finding that 90% of samples contained residues between .26 ppm and 18.5 ppm, barely under the allowed food tolerance level of 20ppm. A 2014 Boston University study had indicated that both organic and conventional honey contained glyphosate concentrations despite […]

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22
Mar

Environmental and Farm Groups Challenge Toxic Pesticides Used in Genetically Engineered Crops

(Beyond Pesticides, March 22, 2017) Today, a coalition of farmers and environmental and public health organizations filed a lawsuit against the Environmental Protection Agency (EPA) for approving agrochemical giant Dow Chemical’s toxic pesticide combo, Enlist Duo, among the newer more highly toxic pesticide mixtures used in genetically engineered (GE) herbicide-tolerant crops. Comprised of glyphosate and 2,4-D (50% of the mixture in the warfare defoliant Agent Orange), Enlist Duo is typically marketed alongside commercial crops like corn, cotton and soybeans that are engineered to withstand pesticide exposure, leading to problems of resistance and driving the evolution of super weeds. This is the third lawsuit challenging EPA approval of Enlist Duo by petitioners, which include Beyond Pesticides, National Family Farm Coalition, Family Farm Defenders, Pesticide Action Network North America, Center for Food Safety, and Center for Biological Diversity, represented jointly by legal counsel from Earthjustice and Center for Food Safety. The lawsuit charges that approval of Enlist Duo “will lead to sharply increased spraying of toxic pesticides, harming farmers, neighboring crops, and wildlife.” Specifically farmers’ health and financial positions stand to be heavily impacted by the approval of Enlist Duo, as increased use will result in increased pesticide drift, an alarming concern especially […]

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21
Mar

California Weakens Rules to Protect Children from Pesticide Drift, Comment Period Open until April 4

(Beyond Pesticides, March 21, 2017) Last week, the California Department of Pesticide Regulation (CDPR) released revised rules regarding notification of pesticide applications near schools, weakening standards despite opposition from community and public health groups. The new rules rescind a requirement that schools be granted 48 hours prior notification for a planned application of agricultural pesticides within ¼ mile of a school site. CDPR has re-opened public comments on the new rules, and concerned residents have until April 4 to submit a short statement urging increased protections to the Department at dpr16004@cdpr.ca.gov. Public health, farmworker, and community groups had urged CDPR to strengthen, not weaken common-sense protections for children’s health. As the rules currently stand, applications of toxic, drift-prone pesticides will only be restricted within ¼ mile of a school site, and only during the hours of 6am to 6pm on weekdays. The original proposal required 48 hour prior notification for other agricultural pesticide applications occurring within ¼ mile of school sites during these times. However, CDPR’s revised rules now only require 48 hour notification if the pesticides applied are not on a list provided to school officials at the beginning of the year. Applicators will still be required to submit annual reports […]

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16
Mar

Monsanto and EPA Collude to Fight Cancer Classification of Roundup (Glyphosate), according to Court Released Documents

(Beyond Pesticides, March 16, 2017) In a lawsuit filed by cancer victims, a federal judge on Tuesday unsealed documents that raise questions of collusion between officials at the U.S. Environmental Protection Agency (EPA) and Monsanto to fight a cancer classification for the company’s flagship product, Roundup (glyphosate). The judge’s ruling comes in a lawsuit against Monsanto, charging that the company’s herbicide caused the plaintiffs’ non-Hodgkin’s lymphoma. According to the New York Times, the court documents “include Monsanto’s internal emails and email traffic between the company and federal regulators [and] suggested that Monsanto had ghostwritten research that was later attributed to academics.” The California lawsuit was brought on following the determination and listing of glyphosate as a probable human carcinogen by the World Health Organization’s International Agency for Research on Cancer (IARC) in 2015. The released files show that Monsanto was “tipped off to the [IARC] determination by a deputy division director at the EPA, Jess Rowland, months beforehand. That led the company to prepare a public relations assault on the finding well in advance of its publication,” according to the released documents. According to Monsanto’s internal emails, Mr. Rowland had promised to fend off efforts by the Department of Health and Human Services […]

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07
Mar

Common Household Pesticides Again Linked to Behavioral Problems in Children

(Beyond Pesticides, March 7, 2017) Another study, published by a team of French scientists in the journal Occupational and Environmental Medicine, links childhood behavioral problems to pyrethroid insecticide exposure. Synthetic pyrethroids are a class of insecticides that have increased in use over the past decade due to assumptions that they pose fewer risks to human health than older pesticide chemistries, such as organophosphates. However, this latest study is part of a growing body of research showing that pyrethroids share similar neurocognitive health concerns as these older pesticides. .   In this research, scientists investigate the interplay between pyrethroid exposure and behavioral problems through a longitudinal cohort study, which tracks levels of pyrethroid metabolites, or breakdown products, in the urine of mothers beginning between six and 19 gestational weeks and then in their children up through six years of age. Children’s behavior is measured through a screening questionnaire known as the Strengths and Difficulties Questionnaire (SDQ). SDQ measures how social a child is (altruism), whether the child has difficulty sharing problems or asking for help (internalizing disorders), as well as how defiant or disruptive a child is (externalizing disorders). The study controls for a number of confounding factors, such as weight, education, location (rural or […]

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02
Mar

European Commission Postpones Vote to Define and Regulate Endocrine Disrupting Chemicals

(Beyond Pesticides, March 2, 2017) On Tuesday, the European Commission (EC) refrained from voting on proposed scientific criteria that would have identified endocrine disrupting chemicals (EDC) and led to regulation on their use in EU countries. This sends the Commission back to the drawing board on the proposal, on which they hope to eventually take a formal vote. The failure to move forward with defined criteria on these hazardous chemicals, which are present in pesticides, biocides, and self-care products, is still largely due to the disagreements of voting member states over the rules reflecting hazard or risk-based criteria. There have been several other meetings of the member states on this proposal, including a meeting in December which highlighted the inadequacies of the criteria. After this meeting, according to Bas Eickhout, of the Greens-European Free Alliance, “Under the Commission’s criteria, it is likely that not a single substance would be identified as an endocrine disrupter, and they would effectively escape specific regulation.” This all follows on the weak regulations issued by the EC in June 2016 to regulate endocrine disruptors in pesticide products, which ultimately undermine the precautionary legal standard that governs pesticide usage in Europe. Many scientists and advocacy organizations criticized […]

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27
Feb

Poisoning Feral Hogs Raises Safety and Environmental Concerns

(Beyond Pesticides, February 27, 2017)  Texas has been dealing with a feral hog issue for many years, however recently Texas Agriculture Commissioner Sid Miller approved the use of a toxic rodenticide in an effort to control feral hog populations, a decision hunters and trappers oppose because the pesticide will poison prey and wreak havoc on ecosystems where the hogs live. The estimated population of the feral hog population is about 1.5 million in the state of Texas, where they can cause extensive damage to property, crops, and native wildlife. Wild hogs have been considered to be one of the most destructive invasive species in the U.S. The feral hog population, close to six million, span 39 states and four Canadian provinces. Commissioner Miller, in announcing the widespread use of toxic pesticide referred to the problem as the “feral hog apocalypse.” Damage caused by wild hogs has been estimated to reach well into the millions. Smithsonian Magazine has reported the annual damage caused by feral hog populations to be around $400 million. The Texas Parks and Wildlife website states that hogs are opportunistic omnivores.  Feral hogs enjoy eating domestic agricultural crops, such as corn, soybeans, peanuts, potatoes, watermelons and cantaloupe. They can cause […]

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22
Feb

Pesticide Spills and Accidents Put Pesticide Applicators at Increased Risk for Prostate Cancer

(Beyond Pesticides, February 23, 2017) Male pesticide applicators who experienced a pesticide spill or another related accident are more likely to harbor changes in their DNA associated with an increased risk of prostate cancer, according to a recent paper published in the journal, Environmental and Molecular Mutagenesis. While the relationship between pesticide exposure and prostate cancer is not new, this study adds to the growing body of evidence that high exposure to specific pesticides may lead to the development of prostate and other cancers. The analysis finds that after experiencing one of these exposure events, men are more likely to have higher DNA methylation of a gene linked with an increased risk of developing prostate cancer. DNA methylation is a form of gene regulation that, if disturbed, can result in gene expression changes that can cause cancer. The researchers used data from the ongoing Agricultural Health Study (AHS), which is a long-term cohort study evaluating cancer and other health outcomes of pesticides applicators and their spouses in North Carolina and Iowa. This paper, High pesticide exposure events and DNA methylation among pesticide applicators in the agricultural health study, analyzed a sample size of 596 male pesticide applicators who underwent three phases of […]

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15
Feb

Lawsuit Charges that Monsanto and EPA Colluded to Stop Agency from Reaching Cancer Finding for Glyphosate (Roundup)

(Beyond Pesticides, February 15, 2017) Plaintiffs in a lawsuit against Monsanto, charging that its product Roundup caused their non-Hodgkins lymphoma (NHL), have cited the Environmental Protection Agency’s (EPA) collusion with the company to block the agency from concluding that the manufacturer’s product Roundup causes cancer, according to investigative reporter Carey Gilliam, writing in the Huffington Post. The filing states that EPA made an effort “to protect Monsanto’s interests and unfairly aid the agrichemical industry.”Glyphosate has been linked to cancer  in the independent scientific literature and is listed as a probable human carcinogen by the World Health Organization’s International Agency for Research on Cancer (IARC). Issues of suppression have also been uncovered, as Monsanto’s lawyers have filed claims to prevent information  turned over to plaintiffs’ lawyers during discovery from inclusion on the public record. This is just the latest development in a variety of lawsuits aimed at Monsanto, including a challenge by a peach farmer over the illegal spraying of the herbicide Dicamba and the recent victory by the state of California to list glyphosate products as cancer causing. In the current case, a multitude of personal injury claims made by those suffering from, or that have lost loved ones to, NHL have been condensed into […]

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09
Feb

Health Canada Will Begin Pesticide Testing of Cannabis After Recalls and Consumer Exposure

(Beyond Pesticides, February 9, 2017) The failure of the U.S. pesticide regulatory system to protect marijuana users was highlighted as Health Canada announced Tuesday that it would begin conducting random pesticide residue testing of marijuana products to ensure that only registered products are being used in medical marijuana production. This comes on the heels of voluntary recalls in 2016 by two licensed Canadian cannabis producers due to the presence of the prohibited pesticides bifenazate, myclobutanil, and pyrethrins in or on marijuana products. Especially concerning is the detection of myclobutanil, a powerful fungicide that, when heated, converts to the hazardous gas hydrogen cyanide. The detection of these toxic chemicals in medical marijuana products is distressing since many users have compromised immune systems or health conditions that make them more susceptible to toxic chemicals. Moves by several states in the U.S. to curb illegal pesticide use in marijuana contain significant pitfalls and loopholes that allow contaminated cannabis to enter the market, where it threatens public health. Without examination of residues in inhaled, ingested, or absorbed cannabis, the user’s health is not protected by pesticide registration addressing other uses. In addition, environmental impacts associated with growing practices are generally ignored. On January 9th, […]

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06
Feb

California Regulators Sued for Allowing Increased Use of Toxic Fumigant without Public Input

(Beyond Pesticides, February 6, 2017) California Department of Pesticide Regulation (CDPR) rules that allow greater use of the highly toxic fumigant Telone, while decreasing protections for the public, have been challenged in California court. On January 31, attorneys representing Juana Vasquez, a farmworker in Ventura County, along with Californians for Pesticide Reform (CPR) and Pesticide Action Network North America (PANNA), filed suit in the Superior Court of California against the California Department of Pesticide Regulation (CDPR). The suit claims that CDPR failed to follow required public procedures in developing new rules for 1,3-Dicholopropene (1,3-D), which is an active ingredient in the product Telone and has many documented health risks, including cancer and kidney and liver damage. In October 2016, CDPR released new rules that allow the continued use of Telone and decrease protections for public health by permitting increased usage. CDPR and many news outlets reported the rule change as a tightening of the restrictions, but in reality, the new rules increase the previous annual cap from 90,250 pounds to 136,000 pounds per township, a defined area of 6×6 miles. These new rules went into effect on January 1, 2017, allowing for 1,3-D’s continued use in strawberry fields, vineyards, almond […]

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02
Feb

Common Pesticide Ingredient Labeled “Inert” Increases Honey Bee Susceptibility to Virus

(Beyond Pesticides, February 2, 2017) A commonly used inert pesticide ingredient negatively affects the health of honey bees by making larvae more susceptible to a virus, according to a recently published study in the journal, Nature. One of the authors of the study, Julia Fine, PhD candidate, stated that the findings, “Mirror the symptoms observed in hives following almond pollination, when bees are exposed to organosilicone adjuvant residues in pollen, and viral pathogen prevalence is known to increase. In recent years, beekeepers have reported missing, dead and dying brood in their hives following almond pollination, and exposure to agrochemicals, like adjuvants, applied during bloom, has been suggested as a cause.” The study assessed honey bee larval development after exposure to a continuous low dose of Sylgard 309, a surfactant, in their diet. This organosilicone surfactant is commonly used on agricultural crops, including tree fruits, nuts, and grapes. Their results reveal that honey bee exposure to chemical surfactants such as Sylgard 309 led to higher levels of Black Queen Cell Virus and when the bee larvae were exposed to the surfactant and virus simultaneously, “the effect on their mortality was synergistic rather than additive.” This research comes at a time when […]

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01
Feb

North Miami Passes IPM Plan in Response to Local Activism

(Beyond Pesticides, February 1, 2017) Last week in North Miami, the City Council took a significant step that could reduce pesticide use in the community. The Council adopted an Integrated Pest Management (IPM) policy modeled after a plan developed by San Francisco in the mid-90’s. The plan does not ban pesticides and herbicides, but instead aims to reeducate citizens and county workers on least-toxic pest management strategies with the goal of eliminating toxic pesticide use on city property.  The IPM plan does not address pesticide use on private property, due to state preemption of local authority. With the passage of the North Miami’s resolution, city operatives will now be asked to give preference to available, safe and effective non-pesticide alternatives and cultural practices. As stated in the resolution’s Integrated Pesticide Management Program Guidelines, the goal of the policy is “to eliminate the application of all Toxicity Category I and Category II pesticide products by January 2018.” On top of eliminating certain pesticide categories, the resolution also calls for staff training and expert consultants, both of which have the potential to help ease the transition in pursuit of the 2018 goal, and priority will be given to efforts to reduce or eliminate pesticide use near […]

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31
Jan

Judge Rules Against Monsanto, Allows California to List Glyphosate Products as Cancer Causing

(Beyond Pesticides, January 31, 2017) A tentative ruling last week by Fresno County Superior Court Judge Kristi Culver Kapetan moves California closer to listing glyphosate (Roundup) as a carcinogen under the state’s Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65). Monsanto, a leading manufacturer of glyphosate under its Roundup brand, sued California to stop the listing, as it would require cancer warning labels be placed on its end-use product. The company indicates it will challenge the tentative ruling. California’s proposed to list glyphosate as a carcinogen after a 2015 determination of the International Agency for Research on Cancer, a United Nations body under the World Health Organization, that the chemical is a cancer-causing agent for humans based on laboratory studies. Monsanto refutes these claims, and since the determination has worked directly, and through proxy organizations, to discredit and attack IARC, as well as individual scientists that have participated in its decision-making process. Shortly after IARC’s Monograph on glyphosate, the German Federal Institute for Risk Assessment (BfR), a Monsanto-supported group, released a report dismissing glyphosate’s link to cancer. In October of last year, the U.S. House of Representatives’ Committee on Oversight and Government Reform, led by Rep. Jason Chaffetz […]

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25
Jan

Study Links Carbamate Insecticides to Diabetes and other Metabolic Diseases

(Beyond Pesticides, January 25, 2017) A study conducted at the University of Buffalo recently revealed a connection between two common insecticides and an increased risk for certain metabolic diseases, including diabetes. Researchers found that by binding to and disrupting melatonin receptors that control numerous physiological functions, chemicals such as insecticides can affect melatonin levels, creating a higher risk for metabolic diseases to develop. The study, Carbamate Insecticides Target Human Melatonin Receptors, was published in Chemical Research in Toxicology and was funded by a grant from the National Institute of Environmental Health Sciences, which is part of the National Institutes of Health. The implicated chemicals in this research, carbaryl and carbofuran, are notoriously dangerous carbamate insecticides. Carbamates share structural characteristics and an ability to inhibit acetylcholinesterase (AChE), an enzyme important for the transmission of nerve impulses. When AChE is inhibited, acetylcholine accumulates leading to overstimulation of neurotransmitters, resulting in muscle weakness, confusion, and paralysis, among other symptoms. Carbaryl is said by EPA to be “one of the most widely applied insecticides in the U.S.,” since use began in 1959, with 10-15 million pounds used annually. It is a broad-spectrum insecticide used on a variety of crops, in forestry and on ornamentals, in […]

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11
Jan

Glyphosate Implicated in Fatty Liver Disease

(Beyond Pesticides, January 11, 2017) Ultra-low doses of glyphosate formulations fed to rats is linked to an increased likelihood of developing non-alcoholic fatty liver disease (NAFLD), according to a recently published study in the journal Nature. A lead author of the study, Michael Antoniou, PhD, stated that the findings are “very worrying as they demonstrate for the first time a causative link between an environmentally relevant level of Roundup consumption over the long-term and a serious disease.” The findings point to the growing need to eliminate the widespread use of this herbicide, as it has already been implicated in endocrine disruption, reproductive effects, and kidney and liver damage. The researchers analyzed female rat livers obtained from a previous 2-year study on Roundup toxicity using molecular profiling techniques. These rats were administered Roundup via drinking water at a concentration of 0.1 ppb, which is an allowable level within both the U.S. and the European Union. The molecular analyses conducted by researchers on the internal organs of the rats fed Roundup included testing of liver cell disturbances. Overall, ultra-low dose glyphosate-formulation exposure led to observations of biomarkers also seen in fatty liver disease. These findings have human health implications “since NAFLD is predicted to be the […]

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