Archive for the 'tebuconazole' Category
25
Mar
(Beyond Pesticides, March 25, 2025) An editorial in Expert Review of Cardiovascular Therapy finds that triazole fungicides pose a significant risk of cardiotoxicity with “growing concerns regarding their safety for human health, especially in long-term exposure,” the authors share. After analyzing the known mechanisms of cardiotoxicity of triazole pesticides in mammals, they conclude that “the most effective approach to mitigating triazole-induced cardiotoxicity lies in prevention.” Triazoles, a class of fungicides, target fungi by inhibiting the biosynthesis of ergosterol, an essential component of their cell membranes. As the researchers share, “Compounds such as tebuconazole, propiconazole, and difenoconazole are among the most used triazoles in agriculture.” Triazoles are utilized as antifungal medications, despite the rise of resistant infections, in addition to their use as systemic pesticides on many fruit and vegetable crops, including grapes, wheat, corn, and soybeans.  As Beyond Pesticides’ previous coverage indicates, many triazole fungicides in the U.S. are registered for use despite evidence of endocrine disruption established over a decade ago in a U.S. Geological Survey report. These pesticides exhibit common mechanisms of toxicity often disregarded in U.S. Environmental Protection Agency (EPA) risk assessments, with a multitude of studies showcasing the myriads of health threats that the agency does […]
Posted in Cardiovascular Disease, difenoconazole, Endocrine Disruption, Fungicides, Oxidative Stress, Propiconazole, tebuconazole | No Comments »
11
Mar
(Beyond Pesticides, March 11, 2025) A study in Toxics analyzes ipconazole, a triazole fungicide often used as a coating on treated seeds and as a foliar treatment on the leaves of plants. “Triazole pesticides are widely used throughout the world, but their abuse causes toxic effects in non-targeted organisms,” the researchers state. In the current study, unintended reproductive effects are noted in male sheep (ram) and pigs (also known as porcine or swine). This research focuses on the impact of ipconazole exposure on spermatozoa (sperm) in two mammal species and finds spermiotoxicity through significantly reduced sperm viability, as well as alterations in enzyme and gene expression related to fertility. “To our knowledge, this is the first study to evaluate the cytotoxic effect of the triazole ipconazole on mammalian spermatozoa,” the authors share. This analysis utilizes semen samples from the Reproductive Biotechnology Laboratory of the Major National University of San Marcos in Lima, Peru, the university where six of the nine researchers are Faculty of Veterinary Medicine.  “The sperm were exposed to ipconazole concentrations of 1, 5, 10, 50 and 100 µM, and to a control without ipconazole,” they say. Similar concentrations have been used in previous cytotoxicity studies with ipconazole. […]
Posted in difenoconazole, Endocrine Disruption, Epigenetic, Infertility, Ipconazole, Livestock, men's health, Oxidative Stress, Peru, Reproductive Health, tebuconazole | No Comments »
25
Feb
(Beyond Pesticides, February 25, 2025) A literature review of over 90 scientific articles in Agriculture documents microplastics’ (MPs) increase in the bioavailability, persistence, and toxicity of pesticides used in agriculture. The interactions between MPs and pesticides enhance the threat of pesticide exposure to nontarget organisms, perpetuates the cycle of toxic chemical use, and decreases soil health that is vital for productivity. “The increasing presence of MPs in agricultural ecosystems has raised concerns about their impact on pesticide bioavailability, efficacy, and environmental behavior,” says study author Kuok Ho Daniel Tang, PhD, a global professor in the Department of Environmental Science at the University of Arizona. He continues, “These synthetic particles interact with pesticides through adsorption and desorption processes, altering their distribution, persistence, toxicity, and uptake by plants and other organisms.” Microplastics in the Environment As Beyond Pesticides has previously reported, microplastics are ubiquitous and threaten not only human health but all wildlife in both aquatic and terrestrial ecosystems. The universal distribution of plastics means that they cannot be avoided. Humans and other organisms take up plastics in the form of microparticles and nanoparticles by inhalation, ingestion, and skin contact every day. Microplastics are about the width of a human hair; nanoplastics […]
Posted in Agriculture, Alternatives/Organics, Atrazine, Azoxystrobin, Biosolids, Carbendazim, Chlorpyrifos, Imidacloprid, Metolachlor, Myclobutanil, National Organic Standards Board/National Organic Program, neonicotinoids, Oxidative Stress, Persistence, Pesticide Efficacy, Plastic, pyraclostrobin, simazine, soil health, synergistic effects, tebuconazole | 1 Comment »
07
Aug
(Beyond Pesticides, August 7, 2024) Using mass spectrometry techniques, researchers in Luxemburg and France detect 69 biomarkers of pollutants and pesticides—12 of which are banned—in hair samples from over 200 French children. This study, published in Environment International, is the first to target over 150 biomarkers in a single hair sample, which “represents the most comprehensive assessment of chemical exposome in humans,” the authors say. All children in the study were 3.5 years old and recruited from the Étude Longitudinale Française depuis l’Enfance (ELFE) [French Longitudinal Study since Childhood] cohort in the country of France, a major pesticide consumer in Europe. The ELFE survey is a joint project between the French Institute for Demographic Studies (INED) and the National Institute of Health and Medical Research (INSERM), which provides the first comprehensive national scientific investigation of children in France by following them from birth to adulthood. Through analysis of hair samples from children in the ELFE cohort, this study evaluates pesticide exposure and compares it with prenatal exposure data from their mothers while also, according to the scientists, “investigat[ing] the roles of children’s biological sex and geographical differences as possible determinants of exposure.” Exposure to pesticides during early childhood poses significant […]
Posted in Azoxystrobin, Carbaryl, Children, Endosulfan, Fipronil, Heptachlor, hexachlorobenzene (HCB), International, Malathion, Metolachlor, organochlorines, Permethrin, Piperonyl butoxide (PBO), Synthetic Pyrethroid, tebuconazole | 1 Comment »
15
Mar
(Beyond Pesticides, March 15, 2024) Toxic pesticides harm all beings and ecosystems, including coral reefs. Large benthic foraminifera (LBF) are single-celled organisms found on reefs that face adverse metabolic impacts after exposure to the weed killer glyphosate and insecticide imidacloprid, according to a study published in Marine Pollution Bulletin. The study found that “even the lowest doses of the fungicide and herbicide caused irreparable damage to the foraminifera and their symbionts.” Beyond Pesticides reiterates our mission of banning toxic petrochemical pesticides by 2032 and that this goal applies to land and water exposure to pesticides. LBFs are typically used as bioindicators for coral health because they are found in substantial quantities and gathering data is not intrusive or damaging to reef health. Researchers in this study screened three different herbicides (one insecticide, one fungicide, and one herbicide) at three different concentration levels. The experiments were performed in six well-samples, each with 10mL of filtered artificial seawater and a singular LBF. The control plates are artificial seawater and the experimental plates include artificial seawater with the addition of three pesticides (imidacloprid, glyphosate, and tebuconazole). Each pesticide was applied at low, medium, and high doses to measure the direct impacts of each […]
Posted in Aquatic Organisms, Glyphosate, Imidacloprid, Oceans, tebuconazole, Uncategorized, Water | No Comments »
29
Aug
(Beyond Pesticides, August 29, 2023) A study published in Insect Biochemistry and Molecular Biology finds the widely used azole fungicide, tebuconazole, has damaging impacts on the redox homeostasis (the process of maintaining balance between oxidizing and reducing reactions) and fatty acid composition in honey bees’ brain via oxidative stress. Acute, field-realistic sublethal exposure to tebuconazole decreased the brain’s antioxidant capacity, key antioxidant defense systems, and oxidative degradation and alteration of lipids (fats) in the brain. Thus, this study adds to the scientific literature on the adverse effects of chemical exposure on pollinator health, especially in sublethal concentrations. Degenerating cognitive skills can threaten honey bee survivability, decreasing colony fitness and individual foraging success. Much research attributes the decline of insect pollinators (e.g., commercial and wild bees and monarch butterflies) over the last several decades to the interaction of multiple environmental stressors, from climate change to pesticide use, disease, habitat destruction, and other factors. Pollinator declines directly affect the environment, society, and the economy. Without pollinators, many plant species, both agricultural and nonagricultural, will decline or cease to exist, as U.S. pollinator declines, particularly among native wild bees, depress crop yields. In turn, the economy will take a hit, since much of the economy (65%) depends upon the […]
Posted in Agriculture, Environmental Protection Agency (EPA), Fungicides, Increased Vulnerability to Diseases from Chemical Exposure, Pollinators, tebuconazole, Uncategorized | No Comments »
01
Oct
(Beyond Pesticides, October 1, 2019) Commonly used fungicides induce trophic cascades that can lead to the overgrowth of algae, according to research published in the journal Chemosphere. While the current process for regulating pesticides in the U.S. focuses on the acute toxicity of pesticides, and may consider some chronic impacts, real world complexities as described in the current study are not reviewed. This gap in our assessment can lead to significant adverse effects not just on individual species, but entire ecosystems. Researchers investigated how fungal parasites known as chytrids control the growth of phytoplankton. While some strains of chytrids are notorious for their impact to frog species, some do in fact provide important stopgaps within ecosystems. “By infecting cyanobacteria, parasitic fungi limit their growth and thus reduce the occurrence and intensity of toxic algal blooms,” says IGB researcher Ramsy Agha, PhD, co-author the study. “Whereas we usually perceive disease as a negative phenomenon, parasites are very important for the normal functioning of aquatic ecosystems and can — as in this case — also have positive effects. Pollution by fungicides can interfere with this natural process,” the researcher adds. The agricultural fungicides tebuconazole and azoxystrobin were tested on chytrid-infected toxic bloom-forming […]
Posted in Agriculture, Azoxystrobin, Fungicides, tebuconazole, Uncategorized | No Comments »
30
Nov
(Beyond Pesticides, November 30, 2018) A study published this month in Science of the Total Environment reveals numerous pesticide residues persisting in soil, harming the viability of agricultural lands and increasing risk of off-site contamination. Funded by the Horizon 2020 programme of the European Commission, researchers from the European Diverfarming project at the University of Wageningen in the Netherlands suggest nations urgently reevaluate conventional land use and inputs including water, energy, fertilizers, machinery and pesticides. Researchers decrying the lack of soil protection policies endeavored to determine which pesticides had the highest soil persistence and toxicity to non-target species. Three hundred seventeen surface soil samples were analyzed from 11 European countries. Selected countries were those with the largest amounts of active agricultural land, characterizing six distinct cropping systems. Sampled soils purposefully represented different soil properties and were taken from crops with the highest pesticide use per hectare. Samples were then analyzed for the concentration of 76 pesticide residues. These 76 pesticides were selected as being most often applied on conventional crops. Eighty-three percent of samples contained varying degrees of pesticide residues, with 25 percent showing one pesticide residue and 58 percent showing mixtures of two or more. Only 17 percent of […]
Posted in Biodiversity, Contamination, contamination, DDT, Disease/Health Effects, Fungicides, Genetic Engineering, Glyphosate, International, Persistence, Pesticide Residues, tebuconazole, Uncategorized | No Comments »
30
Jul
(Beyond Pesticides, July 30, 2013) A recent study published in Environmental Toxicology and Chemistry found levels of pesticide contamination from agricultural drift in Pacific Tree frogs in remote mountain areas including national parks. The study supports past research on the pesticide transport through atmospheric dust and rain. To conduct the study, researchers collected Pacific Chorus frogs, as well as water and sediment samples, from seven ponds ranging from Lassen Volcanic National Park at the northern most location of Central Valley to the Giant Sequoia National Monument. The samples were tested for 98 types of pesticides, traces of which were found in frog tissues from all sites. Two fungicides, pyraclostrobin and tebuconazole, and one herbicide, simazine, were the most frequently detected compound. This was the first time these compounds have ever been reported in wild frog tissues. According to the study, chemical concentrations are often higher in the frog tissue than the environment. This happens as frogs store up small exposures over time, allowing pesticides to bioaccumulate in their bodies. Exposure to pesticides can decrease frog’s immune system and increase their risk of disease. Continual pesticide exposure has led to dramatic declines in amphibian populations. Amphibians are considered the most threatened […]
Posted in Agriculture, California, Pesticide Drift, simazine, tebuconazole, Water, Wildlife/Endangered Sp. | No Comments »
17
Nov
(Beyond Pesticides, November 17, 2010) Researchers with the U.S. Geological Survey (USGS) have found a dozen agricultural fungicides in the waters and sediments downstream of farms and orchards in western states. Presented November 8, 2010 at the annual meeting of the Society of Environmental Toxicology and Chemistry (SETAC) in Portland, Oregon, the findings represent the first such data on fungicides in the western U.S. Farmers routinely use fungus-killing compounds to spray or dust food crops, such as strawberries, corn, and soybeans. Some crops receive up to a dozen doses per growing season. Nationwide, fungicide use has risen considerably since the 1990s, reaching 350 million pounds in 2001. However, the environmental prevalence and effects on wildlife and ecosystems, particularly of newer fungicides, are poorly understood, says Kathryn Kuivila, PhD, of the USGS California Water Science Center. Environmental monitoring programs monitor concentrations of few or no fungicides, she notes. The study entitled, “Occurrence of Azoxystrobin, Propiconazole, and Selected Other Fungicides in US Streams, 2005—2006,” documents the occurrence of fungicides in select U.S. streams soon after the first documentation of soybean rust in the U.S. and prior to the corresponding increase in fungicide use to treat this problem. Water samples were collected from […]
Posted in California, Idaho, Metalaxyl, Myclobutanil, Propiconazole, tebuconazole, Tebuthiuron, Water | No Comments »
