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Daily News Blog

Archive for the 'Chemicals' Category


10
Jul

Studies and Actions Advance Safer Management and Alternatives to Toxic Mosquito and Insect Control

(Beyond Pesticides, July 10, 2026) An article titled “The science of staying bite-free: Balancing natural essential oils, DEET safety and permethrin,” calls attention to insect management options and the subsequent consequences for health and the environment. “While DEET has long been the go-to standard for warding off bugs, concerns over its strong chemical scent, greasy feel, and ability to dissolve plastic gear and synthetic fabrics have driven a massive surge in alternative options,” the article says. The use of DEET (N,N-diethyl-meta-toluamide) dates back to 1946 when it was developed by the U.S. military and is the most common and widely used active ingredient in commercial insect repellents applied to the skin with a warning to wash off when indoors and take special precautions with use on children. Despite widespread use, long-standing and mounting scientific evidence finds adverse effects with exposure to DEET and other insect repellents like the synthetic pyrethroid permethrin. Health Risks While regulatory bodies like the U.S. Environmental Protection Agency (EPA) claim insect repellents are safe for the general public, research connects DEET and permethrin to a wide array of adverse health effects. Cases of severe reactions, such as neurological symptoms or seizures, have also occurred. Beyond Pesticides’ […]

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09
Jul

Habitat for Biodiversity In or Nearby Chemical-Intensive Agriculture Becomes a Deadly Trap, Study Finds

(Beyond Pesticides, July 9, 2026) In a study published in PLOS One, researchers identify “ecological cascades triggered by intensive, calendar-based pesticide applications,” resulting in “agricultural pesticide regimes [that] fundamentally restructure insect foraging networks through complex, poorly understood community-level pathways.” In comparing chemical-intensive apple orchards with adjacent pesticide-free cemeteries, this study documents the impacts on insect biodiversity with exposure to pesticides, noting that in areas without pesticide applications insect abundance and richness is higher and plant-pollinator networks are stronger. When applying pesticides during peak insect activity, apple orchards create ecological traps and insect pollinator foraging network disruption with cascading effects through the ecosystem that extend beyond acute toxicity. As the authors explain: “The resulting exposure drives sublethal behavioural changes, forcing insects into narrower dietary niches and collapsing the complex web of plant-pollinator interactions. The final outcome is a functionally homogenized insect community, stripped of its diversity and resilience.” To sustain ecological integrity and insect biodiversity, as well as the subsequent ecosystem services they provide, such as pollination, pesticide-free habitats are essential. This study adds to the wide body of science that supports the urgent need for a widescale transition to organic agriculture and land management. Study Importance and Background Nontarget and […]

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08
Jul

More Studies Link Breast Cancer to Pesticide Exposure, Despite U.S. Supreme Court Safety Proclamation

(Beyond Pesticides, July 8, 2026) This piece reports on yet additional new studies linking pesticides to breast cancer. Numerous recent reviews make it clear that pesticide exposure per se raises the risk of breast cancer, across a wide swath of pesticide types. One would think that with the body of science linking breast cancer with pesticide exposure, covered extensively by Daily News and the Pesticide-Induced Diseases Database, a scientific-based regulatory system would respond with a sense of urgency. And yet, that is not the case, as the U.S. Environmental Protection Agency (EPA) establishes “acceptable” rates of disease for individual chemicals or chemical families, but does not evaluate patterns of disease linked to multiple chemical exposure. And so, breast cancer is the most common cancer diagnosed in U.S. women, and women turn to medical intervention with drugs, early surgical intervention, and targeted radiation. Yet, the disease, principally associated with environmental rather than hereditary factors, and treatment cause severe disruption to the lives of women and their loved ones and are devastating to quality of life, while clinical responses can have adverse side effects. Many different pesticides affect cellular processes and structures, including alteration of genetic material, endocrine disruption, cell apoptosis, cell […]

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07
Jul

Documented Contamination of Pesticides in Infant Formula Poses Short-Term and Long-Term Health Risks

(Beyond Pesticides, July 7, 2026) An analysis of scientific literature on pesticide contamination in infant formula reveals a public health issue of food safety for young children with potential lifelong impacts, as published in Environmental Toxicology and Pharmacology. Through a systematic review of research from 1975 to 2025, the authors, from the Department of Public Health and Infectious Diseases at the Sapienza University of Rome (Italy), find residues of pesticides that are linked to deleterious health impacts in infant formula, including insecticides such as organochlorines, organophosphates, pyrethroids, and neonicotinoids, and many herbicides. As the researchers share, the results highlight that: “[T]he contamination of infant formula does not concern a single class of substances, but manifests itself as a heterogeneous and simultaneous set of risks: pesticide residues, heavy metals, persistent environmental contaminants, mycotoxins and compounds released from packaging materials can coexist within the same product. This co-presence of contaminants of different origins confirms that the problem cannot be traced back to a single critical point, but reflects a complex supply chain context, in which each stage—from raw material production to industrial processes, storage and packaging—can contribute to the infant’s final exposure.” In confirming the presence of multiple pesticides within infant formula, […]

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01
Jul

Studies Cite Childhood Cancers Linked to Parental and Residential Pesticide Exposure

(Beyond Pesticides, July 1, 2026) A review in the International Journal of Cancer links pesticide exposure, particularly in areas with high agricultural crop density, to increased risks for childhood cancers. The team of researchers from the University of Nebraska-Lincoln and University of Nebraska Medical Center, in analyzing epidemiologic studies published between January 1980 and September 2022, says that “this scoping review affirms that a robust body of epidemiology literature already informs how parental and childhood exposure to environmental chemical exposures can be associated with children’s incidence of pediatric leukemia and brain cancer.” The scientific literature shows that pediatric cancer, which is a significant cause of morbidity and mortality in children, is associated with exposure to residential pesticides, pesticides ingested through drinking water, parental exposure, and in areas with close proximity to agricultural areas where pesticides are used. Background According to the American Childhood Cancer Organization, over 15,000 children in the U.S. are diagnosed with cancer each year, with pediatric cancer as the second leading cause of death in children 5–9 years of age and the third leading cause of death in children ages 10–14. (See here.) In agricultural states, such as Nebraska, Iowa, Minnesota, Kansas, Illinois, Ohio, and Missouri, incidence […]

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26
Jun

Elevated Toxicity of Naturally Occurring Cyanobacteria Provoked by Pesticide Threatens Aquatic Organisms

(Beyond Pesticides, June 26, 2026) In a study published in Aquatic Toxicology, researchers in Brazil determined that the cumulative toxicity of acetamiprid (a neonicotinoid insecticide) and cyanobacteria (photosynthetic microbes that can produce toxins) has a synergistic effect on the health of aquatic water fleas, or Daphnia. The implications of these findings paint a troubling picture for broader aquatic food webs, as they serve as a bridge species across trophic levels, serving as a primary consumer of plants and algae while also providing energy to secondary and tertiary consumers up the chain. In this context, public health and environmental advocates argue that the combined toxicity of synthetic agrichemicals and naturally occurring toxins is often considered an externality (external cost) borne by the public rather than a direct cost of agricultural production or nonagricultural pest management. “When ecosystems are undermined, so are the economic systems that are relied upon to grow food,” says Max Sano, senior policy and coalitions associate at Beyond Pesticides. “The need for a wholesale transition to organic land management acknowledges this fundamental mismatch and seeks to account for these discrepancies, although policy must ensure that organic farmers have the resources they need to thrive.” Methodology and Main Findings […]

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25
Jun

Registered Pesticides Toxic to Honey Bee Larvae, Study Finds

(Beyond Pesticides, June 25, 2026) In a study comparing pesticide active ingredients (isolated single chemicals) with full pesticide product formulations containing added ingredients (the packaged products that can contain carriers, sticking agents, emulsifiers, etc.), researchers find the full formulation to be generally more toxic. The research evaluates acute and chronic exposures of four mosquito adulticide active ingredients (AIs), three product formulations, and one biological larvicide pesticide formulation containing Bacillus thuringiensis israelensis (Bti) on honey bee larvae in vitro and finds that three of the four exceed levels of concern (LOCs) set by the U.S. Environmental Protection Agency (EPA). EPA publishes Guidance for Assessing Pesticide Risks to Bees in which it identifies levels of harm. The scientists who conducted the study, published in Environmental Challenges, are based at the University of Florida and Auburn University. This study references Bti (Vectobac12AS) as the least toxic product, since the acute LD50 (lethal dose that kills 50% of the test population) is well below EPA-set LOCs. However, the study only focused on whether Bti harms honey bees. In contrast, there are some indications of its potential adverse effects on other beneficial insects, moths, and butterflies (see fact sheet here) and aquatic life, including studies […]

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17
Jun

More Data Links Endocrine-Disrupting Pesticides to Increase in U.S. Breast Cancer

(Beyond Pesticides, June 17, 2026) A study out of Michigan State University reviews robust county-level data on pesticide use and breast cancer incidence rates, determining that there are “modest positive associations” in rural counties in the United States. The findings were published in Cancer Causes & Control. Public health and environmental advocates cite the proliferation of published, peer-reviewed research, like this new study, in support of a societal imperative to eliminate harmful agrichemicals and transition to organic practices. The U.S. and countries worldwide have standards for certified organic production, similar to the U.S. Organic Foods Production Act, that establish required practices, a national list of allowed and prohibited substances, public oversight and a stakeholder board with authority over allowed inputs, certification and inspection of on-farm practices, and an enforcement system to ensure standards compliance. There is limited federal investment in growing the organic sector, despite its productivity, profitability, and protection of healthy ecosystems. The study adds to the body of science that illustrates dramatic deficiencies in the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) under which the U.S. Environmental Protection Agency (EPA) and other federal statutes fall short in addressing the complex exposure patterns and adverse human and environmental effects, […]

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16
Jun

Review of 88 Epidemiologic Studies Links Pesticides to Pediatric Brain Tumors and Leukemia

(Beyond Pesticides, June 16, 2026) If there is one take-home message regarding reducing risk of childhood leukemias and brain cancers, it is to avoid exposure to pesticides during pregnancy—especially indoor insecticides such as flea and tick products, including DEET, household plant and commercial pesticide treatments, and proximity to pesticide applications in agriculture. A review by researchers at the University of Nebraska Medical Center and School of Natural Resources in Omaha considered 88 epidemiological papers published between 1980 and 2022 on pediatric cancer and environmental pesticide exposure and found elevated rates of pediatric cancers associated with pesticide exposure. The reviewers assessed the known associations between the risk of childhood leukemia and brain tumors and their or their parents’ exposure to pesticides, pesticide breakdown products and mixtures. They asked how important known exposures in drinking water were to the children’s risk, and whether genetics is a primary influence on cancer development. The researchers found that the risk of childhood brain tumors increased 1.5 times if pest control products were applied during the entire year before conception. High-grade glioma risk was four times higher when pesticides were applied during pregnancy. Prenatal exposure to flea and tick products raised risk, especially for children diagnosed under […]

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12
Jun

Literature Review Unpacks Synergistic and Cumulative Pesticide Impacts on Aquatic Life

(Beyond Pesticides, June 12, 2026) In a literature review published in Caspian Journal of Environmental Sciences, researchers assessed 27 peer-reviewed studies conducted between 2011 and 2025 on the adverse impacts of insecticides, including neonicotinoids, pyrethroids, organophosphates, chlorpyrifos, and fipronil. Across agricultural and suburban environments, pesticides were detected in the majority (88 percent) of samples. This review builds on the continuous flow of science that highlights the adverse impacts of synthetic pesticide dependency on ecosystems and wildlife that are essential to global biodiversity. Main Findings The researchers, based at a variety of research institutions in Jordan, Uzbekistan, Iraq, and India, refined their search to 27 studies after screening for geographic diversity and empirical robustness; for example, they excluded studies that did not include empirical data, relied solely on nonagricultural contexts, or only assessed exposure through urban wastewater exclusively. Toxicological data assessed include pesticide occurrence, toxicity, and biological responses. This literature review is not a meta-analysis, but rather a narrative synthesis of various findings. The main findings include: Documented Widespread Pesticide Occurrence. In the United States, based on data collected between 2013 and 2017, 88 percent of water samples contained pesticides, with a median of 18 compounds across all sites and 24 […]

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11
Jun

Adding to Wide Body of Science, Study Finds Pesticide Residues in Honey Bee Colonies Cause Acute Mortality

(Beyond Pesticides, June 11, 2026) A study of honey bee colonies in Florida and California, published in Environmental Toxicology and Pharmacology, finds elevated mortality from pesticide residues, including those that have been documented to threaten pollinators. As the authors describe, “While bees die from multiple, often interacting, stressors, here we show single contributors at levels capable of causing acute harm.” The presence of miticides, fungicides, herbicides, and insecticides within the bee colonies, including in the bodies of dying bees, further highlights pesticides as drivers of bee declines. By sampling both dying bees and in-house bees for chemical residues, the researchers are able to compare symptomatic colonies and control colonies. The authors note, “Our findings differ from previous screenings, which cast a broad net, screening agrochemicals in colonies nationwide, and not necessarily from impacted operations.” This study, however, shows the presence of specific pesticide residues in commercially managed colonies after die-off incidences. The neonicotinoid insecticide imidacloprid, in particular, is widely detected and found in high levels, with the researchers identifying the compound as the largest contributor to bee death. Background Scientific literature linking pesticides, including neonicotinoids, to adverse impacts on pollinators continues to mount, as do the devasting population declines of […]

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10
Jun

Paraquat Linked to Parkinson’s Disease in U.S. County with Among the Highest Rates, Supporting Call for a Ban

(Beyond Pesticides, June 10, 2026) Adding to the wide body of science connecting the weed killer paraquat to deleterious health and environmental effects, Investigate Midwest recently released an investigative news article connecting air emissions of paraquat from chemical plants in the Mississippi Basin to Parkinson’s disease, among other adverse health effects. The herbicide is also fatal to humans with a single sip, as documented in the article, entitled “This herbicide is so toxic it’s been banned in over 70 countries. But plants in the South are releasing it into the air.”  In capturing the story of Wayne County, Mississippi, where approximately 20,000 people live surrounded by forest and farmland, Investigate Midwest sheds light on the connection between the Sipcam Agro plant that processes and emits paraquat. The plant is located in the county with among the highest U.S. rates of Parkinson’s disease deaths, the top 7% of all U.S. counties.  Background on Paraquat  Paraquat has been on the market since the 1960s, created by a predecessor of Syngenta. In March of this year, Syngenta announced it would stop producing paraquat in the UK after thousands of lawsuits, primarily by farmers and farmworkers, cite Syngenta’s failure to warn of adverse health effects like Parkinson’s disease. Stopping the production of paraquat in the UK will not prevent paraquat from entering the U.S., as “other companies and other facilities—like the one in Wayne County—will fill the gap, likely increasing the amount of paraquat they handle.”  According to previous data from the U.S. Geological Survey, approximately 11 to 17 million pounds of paraquat were sprayed annually in 2017, which may […]

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05
Jun

Robust Science on Transgenerational Health Effects Tied to Pesticide Exposure, Highlights Regulatory Gaps

(Beyond Pesticides, June 5, 2026) With increasing research covered by Daily News showing pesticides linked to epigenetic effects (alter gene expression), the mechanism has far-reaching implications for protecting health and the environment. It also raises issues related to the regulatory review process, which is inadequate in assessing this mechanism. Since the discovery of DNA, a principle called the “central dogma” has dominated genetics. This dogma states that genetic processes are a one-way street: only changes to DNA in germ cells (eggs and sperm) trigger processes in RNA and then proteins to effect changes in tissues and cells throughout the body. Any suggestion that environmental exposures, for example, could alter gene expression except in the first, exposed generation, was dismissed as “Lamarckian” and unscientific. And only changes to genes themselves could be inherited. The theory of epigenetics began developing in the 1950s, and it gradually became clear that gene expression was modifiable by external factors. Cells do have numerous ways of choreographing genes, determining which ones are turned on and off at which times and in which places. In fact, this choreography is absolutely necessary for the development of an individual from pre-conception through fertilization and the progress of an embryo to […]

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03
Jun

Widely Used Fungicide and Breakdown Products Threaten Consumers and Wildlife by Triggering Oxidative Stress

(Beyond Pesticides, June 3, 2026) A study, published in PeerJ today, by researchers from the University of Wisconsin-Madison in the U.S. and the University of Pisa in Italy, finds that the widely used fungicide fludioxonil and its breakdown products, including a â€forever chemical’ per- and poly-fluoroalkyl substance (PFAS), threaten environmental and human health. Through a review of scientific literature (from 2021-2025) of the ecological and health effects of fludioxonil, the authors find evidence of this chemical’s mechanisms of toxicity, including oxidative stress, that are enhanced as it degrades in the environment. Oxidative stress occurs when there is a disruption of normal cell-signaling and molecular damage, leading to an imbalance of reactive oxygen species (ROS) and free radicals (unstable oxygen molecules) that the body is unable to detoxify. In particular, sunlight exposure causes fludioxonil to break down into a PFAS that is linked to adverse health implications for the environment, wildlife, and humans.  One of the authors, Warren Porter, PhD, is a board member for Beyond Pesticides and presented at the 2021 National Pesticide Forum. Dr. Porter is an emeritus Professor of Integrative Biology and an Ardath and Robert Rodale Professor of Environmental Toxicology, with previous research showing that combinations of commonly used agricultural chemicals in concentrations that mirror levels found in groundwater can significantly influence immune, endocrine, and neurological health in animals. His research also links pesticide exposure in utero to impaired learning, changes in brain function, and […]

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01
Jun

Action Calls for Banning Hazardous and Persistent PFAS Pesticides, as Uses Continue

(Beyond Pesticides, June 1, 2026) In the face of U.S. government inaction, the California state Assembly last week passed legislation to phase out existing agricultural uses and ban new uses of PFAS (perfluoroalkyl and polyfluoroalkyl substances) pesticides. The legislation, AB 1603, which accurately defines PFAS pesticides in accordance with international standards, does allow continued residential, school and park, playing field, and community PFAS pesticide use (including mosquito spraying). The bill now moves on to the state Senate. While advocates say the bill is an important step forward, they point out that the legislation is one of many examples that compromises public and environmental health, as pesticide-associated cancer, degenerative diseases, multigenerational effects, and ecosystem decline escalate. This attack on health and the environment is happening at the same time that organic agriculture and land management prohibits the use of PFAS pesticides and all the petrochemical pesticides and fertilizers with profitable and cost-effective practices. The California victory paves the way for state action as regulators at the U.S. Environmental Protection Agency (EPA) refuse to act on clear scientific findings identifying devastating health and environmental threats. In this context, the bill serves as a call for all states to push for this type of legislation […]

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29
May

Widespread Multiple Pesticide Exposure with Adverse Effects Again Documented in Honey Bee Hives

(Beyond Pesticides, May 29, 2026) In a new study published in Environmental Pollution, researchers detected 15 currently used pesticides (CUPs)—including 10 pesticide compounds detected but not applied within the study’s managed fields— in the pollen of beehives in an environment meant to reflect a typical honey bee foraging range. The detection of pesticides that were not directly applied within the study’s target radius demonstrates the pervasiveness of pesticide drift into soils, streams, and bodies. In this context, public health and environmental advocates continue to call for a wholesale transition to organic land management. The findings are particularly concerning given the toxicity hazards to honey bees associated with pesticide exposure in this study and bolstered by other studies, resulting in documented threats to their health—as reviewed in this Daily News below. Methodology and Background Researchers at the University of Bern and Agroscope, the Swiss government’s agricultural research arm, conducted this research with agricultural land-use data for 2023 and 2024 from the Zurich (provincial/Canton) government. The study area was defined as a 2-kilometer radius around the hive placement site, with 4 active hives over the course of a two-year period (April 10, 2023, through May 3, 2024). The land use within the […]

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21
May

As Rates Rise in Younger People, Early-Onset Colon and Rectal Cancer Linked to Pesticides’ Altering Gene Expression

(Beyond Pesticides, May 21, 2026) An important study by cancer researchers in Barcelona, Spain at once shows a path forward in illuminating the long-term, multi-generational, health damage from pesticide exposures and demonstrates how extraordinarily dilatory U.S. agricultural regulators are in protecting public health. The study, “Epigenetic fingerprints link early-onset colon and rectal cancer to pesticide exposure,” found a robust association between methylation markers (for gene expression associated with cancer) and exposure to a number of pesticides, with the herbicide picloram having the strongest link. Other pesticides with strong associations include the weedkillers atrazine, glyphosate, nicosulfuron, and insecticide esfenvalerate. Colon cancer is expected to double, and rectal cancer to quadruple, in this young age group by 2030. This sharp contrast between age groups suggests that environmental exposures, rather than strictly genetics, are involved. The authors are concerned with the alarming rise in early onset colorectal cancer (EOCRC) not only in the highly developed world but also in less-industrialized countries. This increase appears to be connected with age cohorts and the differences in lifestyle and environmental exposures between older and younger cohorts. According to a commentary on the study by researchers from the Dana-Farber Cancer Institute, in the U.S., the incidence of colorectal […]

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18
May

Call to Ban Organophosphate Insecticides Escalates Amid Inadequate Regulatory Action

(Beyond Pesticides, May 18, 2026) As the studies continue to mount on the adverse effects of exposure to low levels of organophosphate insecticides, the calls for banning the chemicals are growing. Beyond Pesticides announced an action to “Tell Congress, FDA, and EPA that it is past time to stop the manufacture and use of all organophosphate pesticides, which damage the nervous system and brain at low levels.” There are alternatives to these chemicals that support productive and profitable farming operations. Defying the often-repeated claim that organophosphate pesticide effects occur only at high doses, a recent study by researchers at University of California, San Diego, and the FundaciĂłn Cimas del Ecuador in Quito, Ecuador, establishes for the first time the pattern of adverse developmental effects that low-level exposure has on healthy neurological and brain development in children. It is firmly established that widely used organophosphate pesticides in food production and other sites are severely toxic to a broad range of organisms. In what is known as their “classic” mechanism of action, they inhibit acetylcholinesterase (AChE), an enzyme that breaks down the neurotransmitter acetylcholine (ACh), particularly in neuromuscular junctions in the brain. Organophosphates are nerve agents, originally developed by the German company IG Farben (a […]

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15
May

Pesticide Contamination Moves Through the Food Web, From Aquatic Insects to Terrestrial Birds and Bats

(Beyond Pesticides, May 15, 2026) As water bodies continue to be contaminated by pesticides and fertilizers used in chemical-intensive agriculture, international researchers find increasing threats to both aquatic and terrestrial food webs with insect transmission of pesticide residues from water to land. Published in Environmental Pollution, the study authors analyze insect species with complex life cycles “with an aquatic phase as larvae and a terrestrial phase as winged adults when they serve as prey for many aerial insectivores, such as bats and birds.” As the researchers explain, these insects act as vectors, transferring pesticides from water bodies into terrestrial food webs. As a result of studying feces from birds and bats that prey on these insects, the authors find residues of 16 current-use pesticides, two legacy compounds, and six metabolites (breakdown products). The study results illustrate that pesticide contamination occurs through the ingestion of contaminated prey from aquatic systems, as all of the substances recovered in the fecal samples are detected in the water bodies within the study region. The transfer of pesticides from emerging insects to other species in the food web further threatens biodiversity and ecosystem functioning. In summary, the authors state, “Our study is among the first […]

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13
May

Literature Review Documents Enhanced Toxicity of Chemical Mixtures in Aquatic Organisms with PFAS Exposure

(Beyond Pesticides, May 13, 2026) Published in Toxics, a review finds that per- and polyfluoroalkyl substances (PFAS) can heighten the risks to exposed organisms from environmental contaminants. Mixtures of these compounds can negatively impact the nervous, cardiovascular, immune, and reproductive systems, particularly in aquatic organisms, and threaten overall biodiversity. The review highlights synergistic effects (greater in combination) observed in mixtures, such as PFAS with pesticides and microplastics, that can cause enhanced oxidative stress, neurotoxicity, developmental defects, and reproductive dysfunction, among others. “The objectives were to evaluate the toxicological effects of mixtures of the selected contaminants with PFAS on aquatic organisms to better understand biological responses in animals,” the study authors explain. “Based on our review, data suggest that PFAS can modify the toxicity of co-occurring pollutants.” Background PFAS were first created in the 1930s and have since been used in many industries and in the production of many products. The multitude of PFAS sources and exposure routes leads to widespread contamination of the environment and organisms. PFAS in agriculture represents a large source, as PFAS can be pesticide active ingredients, used in the plastic containers that pesticides are stored in, and as surfactants in pesticide products. Additionally, PFAS are used in many other […]

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07
May

Literature Review Links Pesticide Exposure to Increased Risks of Multiple Myeloma, a Blood Cancer

(Beyond Pesticides, May 7, 2026) Adding to the wide body of science on pesticide-induced cancer, researchers from the Icahn School of Medicine at Mount Sinai’s Department of Hematology and Medical Oncology and Department of Environmental Medicine find that environmental and occupational exposures increase the risk of developing multiple myeloma (MM), a type of blood cancer. As published in Blood Reviews, the literature review highlights how exposure to contaminants, such as pesticides, dioxins, combustion byproducts, and ambient air pollution, can cause MM through mechanisms of oxidative stress, DNA damage, and aryl hydrocarbon receptor signaling, as well as influence disease biology through immune dysregulation. “Earlier epidemiologic studies suggested associations between environmental exposures and disease risk, but few have used modern geospatial or exposomic [totality of environmental exposure relating to health effects] methods capable of capturing exposure complexity,” the authors write. They continue: “Advances in data integration, spatial modeling, and molecular profiling now make it possible to revisit these questions with greater precision and biological context. This review summarizes current evidence on environmental exposures in plasma cell disorders and frames a research agenda for integrating exposomic data to improve exposure resolution and evaluate plausible mechanisms in MM.” Background Multiple myeloma is an incurable […]

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06
May

Insecticides Gravely Threaten Honey Bee Gut Microbiome, Study Findings Expand on Previous Research

(Beyond Pesticides, May 6, 2026) Adding to the wide body of science highlighting the adverse effects of pesticides on pollinators, as extensively documented in Daily News and What the Science Shows on Biodiversity, a study published in Insects finds threats to Italian honey bees (Apis mellifera ligustica) following exposure to insecticides with contrasting toxicity levels. Both the high toxicity and low toxicity compounds impact honey bee gut bacteria and gut microbial composition, showing how even “reduced risk” insecticides can have sublethal effects and jeopardize pollinator health. As the authors point out, “Honey bees depend on a small but highly specialized community of gut bacteria that help them digest food, resist infections, and cope with environmental stress.” Because of this, chemicals that disrupt the honey bee gut microbiome can threaten their survival. In the current study, the researchers analyze two compounds to determine adverse impacts on honey bees’ gut microbiota: emamectin benzoate-lufenuron (EB-LFR), an avermectin insecticide with high toxicity, and RH-5849 (1,2-dibenzoyl-1-tert-butylhydrazine), a non-steroidal ecdysone agonist (mimicking the action of the insect molting hormone) and insect growth regulator with reported lower toxicity. The results reveal that both toxicity levels can harm gut microbial composition, with EB-LFR “associated with observed reductions in […]

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01
May

Exposure to Toxic Chemicals, including Pesticides, Tied to Adverse Mental Health in Military Service Members

(Beyond Pesticides, May 1, 2026) A study in Psychiatry Research, entitled “Toxic Exposure and Rates of Suicidal Thoughts and Behaviors Among U.S. Military Veterans,” adds to the body of science linking poorer mental health among military members with exposure to environmental contaminants. While previous research focuses on mental health broadly, the current observational cohort study focuses on exposure to toxic substances and suicidal thoughts and behaviors (STBs) through the analysis of data from 248,926 U.S. veterans enrolled in the Million Veteran Program (MVP). In comparing self-reported exposures to nine toxicants, including Agent Orange, chemical/biological weapons, anthrax vaccine, solvents/fuels, petroleum combustion products, lead, other metals, pesticides, and open-air burn pits, and mental health records, the researchers find that military veterans with higher toxic exposures are more likely to have STBs. The authors also report that these associations occur across all major service cohorts (pre-Vietnam, Vietnam, post-Vietnam, Gulf War, and post-9/11 eras). “Our work contributes to growing evidence that veterans who report more toxic exposures are more likely to have STBs, consistent with greater risk for other mental health outcomes (e.g., depression, PTSD [post-traumatic stress disorder]),” the researchers conclude. Importance and Background Military members experience increased health risks with exposure to environmental […]

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