Archive for the 'organophosphate' Category
08
Jul
(Beyond Pesticides, July 8, 2026) This piece reports on yet additional new studies linking pesticides to breast cancer. Numerous recent reviews make it clear that pesticide exposure per se raises the risk of breast cancer, across a wide swath of pesticide types. One would think that with the body of science linking breast cancer with pesticide exposure, covered extensively by Daily News and the Pesticide-Induced Diseases Database, a scientific-based regulatory system would respond with a sense of urgency. And yet, that is not the case, as the U.S. Environmental Protection Agency (EPA) establishes “acceptable” rates of disease for individual chemicals or chemical families, but does not evaluate patterns of disease linked to multiple chemical exposure. And so, breast cancer is the most common cancer diagnosed in U.S. women, and women turn to medical intervention with drugs, early surgical intervention, and targeted radiation. Yet, the disease, principally associated with environmental rather than hereditary factors, and treatment cause severe disruption to the lives of women and their loved ones and are devastating to quality of life, while clinical responses can have adverse side effects. Many different pesticides affect cellular processes and structures, including alteration of genetic material, endocrine disruption, cell apoptosis, cell […]
Posted in Agriculture, Alternatives/Organics, Breast Cancer, Cancer, Chlorpyrifos, Endocrine Disruption, Environmental Protection Agency (EPA), Microbiome, Monsanto, organophosphate, pyrethroids, Uncategorized | No Comments »
07
Jul
(Beyond Pesticides, July 7, 2026) An analysis of scientific literature on pesticide contamination in infant formula reveals a public health issue of food safety for young children with potential lifelong impacts, as published in Environmental Toxicology and Pharmacology. Through a systematic review of research from 1975 to 2025, the authors, from the Department of Public Health and Infectious Diseases at the Sapienza University of Rome (Italy), find residues of pesticides that are linked to deleterious health impacts in infant formula, including insecticides such as organochlorines, organophosphates, pyrethroids, and neonicotinoids, and many herbicides. As the researchers share, the results highlight that: â[T]he contamination of infant formula does not concern a single class of substances, but manifests itself as a heterogeneous and simultaneous set of risks: pesticide residues, heavy metals, persistent environmental contaminants, mycotoxins and compounds released from packaging materials can coexist within the same product. This co-presence of contaminants of different origins confirms that the problem cannot be traced back to a single critical point, but reflects a complex supply chain context, in which each stageâfrom raw material production to industrial processes, storage and packagingâcan contribute to the infant’s final exposure.â In confirming the presence of multiple pesticides within infant formula, […]
Posted in Alternatives/Organics, Chemical Mixtures, Children, contamination, Herbicides, Insecticides, Italy, neonicotinoids, organochlorines, organophosphate, Pesticide Mixtures, Pesticide Residues, pyrethroids, synergistic effects, Synthetic Pyrethroid | No Comments »
17
Jun
(Beyond Pesticides, June 17, 2026) A study out of Michigan State University reviews robust county-level data on pesticide use and breast cancer incidence rates, determining that there are âmodest positive associationsâ in rural counties in the United States. The findings were published in Cancer Causes & Control. Public health and environmental advocates cite the proliferation of published, peer-reviewed research, like this new study, in support of a societal imperative to eliminate harmful agrichemicals and transition to organic practices. The U.S. and countries worldwide have standards for certified organic production, similar to the U.S. Organic Foods Production Act, that establish required practices, a national list of allowed and prohibited substances, public oversight and a stakeholder board with authority over allowed inputs, certification and inspection of on-farm practices, and an enforcement system to ensure standards compliance. There is limited federal investment in growing the organic sector, despite its productivity, profitability, and protection of healthy ecosystems. The study adds to the body of science that illustrates dramatic deficiencies in the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) under which the U.S. Environmental Protection Agency (EPA) and other federal statutes fall short in addressing the complex exposure patterns and adverse human and environmental effects, […]
Posted in acetamiprid, Aldicarb, Atrazine, Azinphos-methyl, Bensulide, Breast Cancer, carbamate, Carbamates, Carbaryl, Chlorpyrifos, Clothianidin, cypermethrin, Diazinon, dicofol, Dimethoate, dinotefuron, Disease/Health Effects, Disulfoton, Endosulfan, Ethoprop, Fenamiphos, fenpropathrin, Fosetyl, glufosinate, Glyphosate, Imidacloprid, Lindane, Malathion, methoxychlor, Naled, neonicotinoids, organochlorines, organophosphate, Parathion, Permethrin, Propazine, Propoxur, pyrethroids, simazine, terbufos, thiacloprid, Thiamethoxam, Triazines, Tribufos, Triclopyr, U.S. Geological Survey, Uncategorized, Women's Health | 1 Comment »
12
Jun
(Beyond Pesticides, June 12, 2026) In a literature review published in Caspian Journal of Environmental Sciences, researchers assessed 27 peer-reviewed studies conducted between 2011 and 2025 on the adverse impacts of insecticides, including neonicotinoids, pyrethroids, organophosphates, chlorpyrifos, and fipronil. Across agricultural and suburban environments, pesticides were detected in the majority (88 percent) of samples. This review builds on the continuous flow of science that highlights the adverse impacts of synthetic pesticide dependency on ecosystems and wildlife that are essential to global biodiversity. Main Findings The researchers, based at a variety of research institutions in Jordan, Uzbekistan, Iraq, and India, refined their search to 27 studies after screening for geographic diversity and empirical robustness; for example, they excluded studies that did not include empirical data, relied solely on nonagricultural contexts, or only assessed exposure through urban wastewater exclusively. Toxicological data assessed include pesticide occurrence, toxicity, and biological responses. This literature review is not a meta-analysis, but rather a narrative synthesis of various findings. The main findings include: Documented Widespread Pesticide Occurrence. In the United States, based on data collected between 2013 and 2017, 88 percent of water samples contained pesticides, with a median of 18 compounds across all sites and 24 […]
Posted in Aquatic Organisms, Atrazine, Biodiversity, carbamate, Carbamates, Chlorpyrifos, Diuron, Fipronil, Glyphosate, Imidacloprid, neonicotinoids, organophosphate, Pesticide Drift, pyrethroids, thiacloprid, Thiamethoxam, Uncategorized | No Comments »
18
May
(Beyond Pesticides, May 18, 2026) As the studies continue to mount on the adverse effects of exposure to low levels of organophosphate insecticides, the calls for banning the chemicals are growing. Beyond Pesticides announced an action to âTell Congress, FDA, and EPA that it is past time to stop the manufacture and use of all organophosphate pesticides, which damage the nervous system and brain at low levels.â There are alternatives to these chemicals that support productive and profitable farming operations. Defying the often-repeated claim that organophosphate pesticide effects occur only at high doses, a recent study by researchers at University of California, San Diego, and the FundaciĂłn Cimas del Ecuador in Quito, Ecuador, establishes for the first time the pattern of adverse developmental effects that low-level exposure has on healthy neurological and brain development in children. It is firmly established that widely used organophosphate pesticides in food production and other sites are severely toxic to a broad range of organisms. In what is known as their âclassicâ mechanism of action, they inhibit acetylcholinesterase (AChE), an enzyme that breaks down the neurotransmitter acetylcholine (ACh), particularly in neuromuscular junctions in the brain. Organophosphates are nerve agents, originally developed by the German company IG Farben (a […]
Posted in ADHD, Agriculture, BASF, Bayer, behavioral and cognitive effects, Brain Effects, Children, Chlorpyrifos, Corteva, Developmental Disorders, Dow Chemical, Environmental Protection Agency (EPA), Epigenetic Effects, Immunotoxicity, IQ Loss, Nervous System Effects, organophosphate, Take Action, Uncategorized | No Comments »
09
Apr
(Beyond Pesticides, April 9, 2026)Â âThe routine use of common pesticides in agriculture is no longer an ethically viable option for sustainable food production,â according to a new review in Reproduction & Fertility by livestock researcher Whitney Payne, Ph.D. candidate, and Kelsey R. Pool, PhD, of the School of Agriculture and Environment at The University of Western Australia. They base their position on the endocrine-disrupting qualities of many pesticides. The authors describe endocrine-disrupting compounds (EDCs) as âan inescapable feature of modern lifeâ and note that the âfarming systems sit at the intersection of animal health, environmental integrity, and food production.â The review stresses the risks that EDCs pose to livestock, which are seriously understudied. Â EDCs are introduced to cattle, sheep, chickens, goats, and other mammals via pesticides, plastics, and hormone treatments. Since humans consume livestock, the effects of EDCs on animals are not confined to animals themselves. Animal production systems illustrate how EDCs âcan enter diverse food chains and ecosystems from a single source,â the authors write, being introduced by humans for one purpose and returning to affect livestock and humans indirectly through their long-term effects and breakdown products. While regulatory systems typically consider direct and indirect exposure pathways in […]
Posted in Agriculture, Atrazine, Carbamates, neonicotinoids, organophosphate, pyrethroids, Uncategorized | 1 Comment »
27
Mar
(Beyond Pesticides, March 27, 2026) In a study of birth outcomes in Arizona, published in the Journal of Exposure Science & Environmental Epidemiology, researchers find that preconception and prenatal exposure to certain carbamates, organophosphates, and pyrethroids increases the risk of lower Apgar scores, a metric used to assess neonatal health at one minute and ďŹve minutes after birth. The results reveal that exposure to âseveral pesticide active ingredients at any point during preconception and/or pregnancy were associated with increased odds of low Apgar scores: the carbamates carbaryl and formetanate hydrochloride; the organophosphates diazinon and tribufos; and the pyrethroid cypermethrin.â This multi-institutional study, led by the University of Arizona with researchers from Harvard Chan School of Public Health and UCLA Fielding School of Public Health, provides novel insights, as it incorporates pesticide exposure over a 15-year period both before conception and throughout pregnancy. âTo analyze associations of preconception and prenatal exposures to carbamate, organophosphate, and pyrethroid pesticide classes and 25 individual active ingredients with newborn Apgar scores to evaluate the relationship between these exposures and neonatal health,â the authors explain. They continue: âWe used pesticide use registry and birth certificate data from 2006 to 2020, linked as part of the Arizona […]
Posted in Agriculture, Arizona, Autism, behavioral and cognitive effects, Brain Effects, Carbamates, Carbaryl, Children, cypermethrin, Developmental Disorders, Diazinon, organophosphate, Pesticide Drift, pyrethroids, Women's Health | No Comments »
12
Mar
(Beyond Pesticides, March 12, 2026) The science connecting pesticide exposure to neurotoxicity continues to mount. A study in Discover Toxicology highlights neurotoxic pollutants as significant environmental threats, showcasing the adverse impacts on vertebratesâ neurological health from pesticides, including organophosphates, carbamates, and organochlorines. “These substances disrupt normal neurophysiological functions by impairing neurotransmission, generating oxidative stress, provoking neuroinflammation, and initiating neuronal cell death,â the authors say. They continue, âSuch disturbances are linked to cognitive deficits, motor impairments, and abnormal neural development.â Neurological conditions can manifest as headaches, muscle weakness, tremors, paralysis, coordination challenges, vision loss, hallucinations, vertigo, seizures, memory loss, slurred speech, trouble breathing with minimal exertion, and more. The range of adverse effects from low-dose, long-term exposure and low-dose (or subchronic) exposure during developmental phases of life raises serious questions about the adequacy of the regulatory review of pesticides, which focuses on acute high and lethal dose exposure. One study on the neurotoxicity of pesticides, published in Chemosphere, concludes, âNew regulatory and preventive measures to mitigate the neurotoxic effects of pesticides are needed.â (See also Daily News.) Even at low concentration, chronic exposure to pesticides and other environmental contaminants âposes serious ecological and health concernsâ that occur as these chemicals âbioaccumulate […]
Posted in Alzheimers's, Aquatic Organisms, Atrazine, behavioral and cognitive effects, Beneficials, Biodiversity, Brain Effects, Carbamates, Carbaryl, Developmental Disorders, DNA Damage, Glyphosate, Nervous System Effects, organochlorines, organophosphate, Oxidative Stress, Paraquat, Parkinson's, Pesticide Mixtures, Pesticide Regulation, PFAS, synergistic effects, Wildlife/Endangered Sp. | No Comments »
27
Jan
(Beyond Pesticides, January 27, 2026) A three-part study published in Molecular Neurodegeneration draws a connection between Parkinsonâs disease (PD) and the organophosphate chlorpyrifos. âSince chlorpyrifos (CPF) exposure has been implicated as a risk factor for PD, we investigated its association to incident PD and if this association is biologically plausible using human, rodent, and zebrafish (ZF) studies,â the researchers state. Together, the three experiments âstrongly implicate exposure to CPF as a risk factor for developing PD,â as the authors find that exposure, even at very low concentrations, causes selective toxicity to dopaminergic neurons that are critical for functions of movement, cognition, emotion, and more. The results reveal that in humans, long-term residential exposure is associated with more than a 2.5-fold increased risk of developing PD, while exposure in mice causes âmotor impairment, dopaminergic neuron loss, microglial activation, and an increase in pathological Îą-synuclein (Îą-syn) [proteins primarily found in the brain].â The researchers continue, âUsing ZF, we found that CPF-induced dopaminergic neuron loss was at least partially due to autophagy dysfunction and synuclein accumulation, as knocking down LC3 [a protein chain] recapitulated the dopaminergic neuron loss.â These three studies highlight the association of CPF with increased risks for developing PD, as […]
Posted in Agriculture, Aquatic Organisms, behavioral and cognitive effects, Brain Effects, California, Chlorpyrifos, fish, Insecticides, organophosphate, Parkinson's | No Comments »
18
Dec
(Beyond Pesticides, December 18, 2025) A study in the International Journal of Hygiene and Environmental Health finds peak concentrations of organophosphate pesticide (OP) metabolites in the urine of pregnant mothers 6-12 hours after consuming contaminated fruits and vegetables. âHigh detection rates were observed for dimethylthiophosphate (DMTP, 96%), dimethylphosphate (DMP, 94%), diethylphosphate (DEP, 89%), and diethylthiophosphate (DETP, 77%) among 431 urine samples taken from 25 pregnant women, over two 24-hr periods, early in pregnancy,â the researchers report. The levels of metabolites within the urine correlate to the consumption of foods treated with organophosphate pesticides, highlighting the importance of adopting an organic dietâparticularly for pregnant individuals and their children. âIn 2009â2010, 80 pregnant women were recruited from Ottawa, Canada for the Plastics and Personal-care Product use in Pregnancy (P4) Study,â the authors say. âA subset (n = 25) collected multiple spot urines (up to 10 each; total n = 431) over two 24-h periods in early pregnancyâone weekday and weekend dayâwhile logging their food consumption beginning 24 h prior to the first urine void and continuing through the following 24-h urine collection period.â This is the first study looking at the variability of organophosphate metabolites within 24 hours in maternal urine, giving […]
Posted in Agriculture, Alternatives/Organics, Biomonitoring, Canada, Chlorpyrifos, Diazinon, Dimethoate, Insecticides, Malathion, Metabolites, Nervous System Effects, organophosphate, Parathion, Women's Health | No Comments »
20
Nov
(Beyond Pesticides, November 20, 2025) Recent scientific literature finds heightened toxicity associated with pesticide metabolites, the transformation/breakdown products of the parent compounds, that threaten the health of the soil, wildlife, and humans. This research stresses the importance of the U.S. Environmental Protection Agency (EPA) evaluating metabolites, which is currently insufficiently included in regulatory processes. In a literature review in Global Change Biology, the researchers point out multiple areas in which regulations fail to address key criteria, including metabolites, saying: âPesticide risk assessments currently rely on surrogate species and focus primarily on acute lethality metrics, failing to capture the broader impacts on non-target organisms and thus biodiversity. Under the directives of regulatory agencies worldwide, this traditional approach overlooks the complex interactions between multiple stressors, including climate change, land-use shifts, and pesticide transformation products. Pesticide risk assessments must therefore undergo a paradigm shift to account for these complex interactions, which disproportionately affect insect pollinators, other non-target species, and biodiversity at large.â A metabolite is a breakdown product that forms when a pesticide is used in the environment and mixes with air, water, soil, or living organisms. All metabolites fall under the category of transformation products, which is the broader term for any […]
Posted in Agriculture, Biodiversity, Breakdown Chemicals, Chlorothalonil, Environmental Protection Agency (EPA), Imidacloprid, Insecticides, Metabolites, neonicotinoids, organophosphate, Pollinators, Seeds | No Comments »
13
Nov
(Beyond Pesticides, November 13, 2025) A study in Environmental Science & Technology shows that maternal exposure to organophosphate (OP) and pyrethroid insecticides adversely affects newborn health. Through amino acid and acylcarnitine metabolomics (the study of small molecules known as metabolites) with over 400 mother-infant pairs, this research analyzes metabolic pathways linking pesticide exposure to negative birth outcomes. âTo our knowledge, this study is the first to reveal the effect of OP and pyrethroid insecticide exposure on neonatal metabolic signatures, which may elucidate a key role of metabolites in insecticide exposure and birth outcomes,â the authors state. In collecting maternal urine samples in the first and third trimesters, as well as neonatal blood samples after birth, OP and pyrethroid metabolites and metabolomic biomarkers are assessed. Notably, the authors report: âResults indicated that third-trimester maternal urinary levels of 3- phenoxybenzoic acid (3-PBA) and diethyl dithiophosphate (DEDTP) were negatively associated with birth weight. Specifically, a one-unit increase in their ln-transformed [natural logarithm form] concentrations was associated with a 1.508% decrease in birth weight for 3-PBA and a 1.366% decrease for DEDTP.â Additionally, the analyses show that OP and pyrethroid exposure is associated with âdisrupted neonatal amino acids and acylcarnitine profiles, with patterns varying […]
Posted in Agriculture, Biomonitoring, Children, Chlorpyrifos, Cyfluthrin, Developmental Disorders, Flumethrin, Metabolism, Metabolites, organophosphate, pyrethroids, Synthetic Pyrethroid | No Comments »
07
Nov
(Beyond Pesticides, November 7, 2025)Â There is little dispute that modern industrial culture has produced a constellation of related chronic conditions contributing powerfully to human disease. In recent decades, attention has begun to focus on the developmental origins of health and diseaseâprenatal exposures to pesticides, for example, that contribute to diseases in adulthood, such as cardiovascular and metabolic problems, along with the combination, known as cardiometabolic syndrome. Cardiometabolic disorders include obesity, hypertension, cholesterol imbalances, and insulin resistance. The usual suspects blamed for the syndrome are poor diet, physical inactivity, and genetic predisposition. These are all well-established risk factors, but they fail to fully account for the sharp rise in cardiometabolic syndrome globally. Obesity prevalence has doubled and diabetes quadrupled over the last 40 years, according to the Non-Communicable Diseases (NCD) Risk Factor Collaboration. In a study on early life exposure to a pesticide mixture, researchers analyze sex differences in cardiometabolic outcomes from prenatal and early life. The study was conducted by an international team of scientists led by Ana M. Mora, M.D., of the Center for Environmental Research and Community Health at the University of California, Berkeley, using data from the Center for the Health Assessment of Mothers and Children of […]
Posted in Agriculture, Children, Glyphosate, Malathion, metabolic syndrome, Obesity, organophosphate, Permethrin, pyrethroids, Uncategorized | No Comments »
24
Oct
(Beyond Pesticides, October 24, 2025) A literature review published in Science of the Total Environment reports numerous peer-reviewed studies associating prenatal and childhood pesticide exposure to measurable alterations to children’s immune systems, including indicators of immunosuppression and increases in pro-inflammatory cytokines, among other adverse health effects. These immune system alterations are linked to higher infection risk and potentially contribute to autoimmune diseases and allergies later in life. For over four decades, Beyond Pesticides has tracked the peer-reviewed science and identified a preponderance of evidence linking pesticide and chemical-dependent pest management to adverse human and ecological health effects. In this spirit, public health and environmental advocates continue to call for a wholesale transition to organic land management and organic pest management as biodiversity, public health, and climate crises continue to mount. This mission supports the growth of the Parks for a Sustainable Future Program, where nineteen cities in eleven states across the country engage in pilot projects to transition parks, playing fields, and schoolyards to organic management practices and protect the health of children. Background and Methodology âThis study aimed to evaluate the extent of immunotoxicity and correlation between exposure to pesticides and immune system alterations in children under five years […]
Posted in carbamate, Carbamates, Children, Children/Schools, Disease/Health Effects, Immunotoxicity, organochlorines, organophosphate, pyrethroids, Uncategorized | No Comments »
21
Oct
(Beyond Pesticides, October 21, 2025) A study, published in International Journal of Hygiene and Environmental Health, calculates cumulative dietary pesticide exposure and finds a significant positive association between pesticide residues in food and urine when analyzing over 40 produce types. The research uses data for 1,837 individuals from the 2015â2016 National Health and Nutrition Examination Survey (NHANES) and compares them to biomonitoring samples of the participants. According to the researchers, âHere we show that consumption of fruits and vegetables, weighted by pesticide load, is associated with increasing levels of urinary pesticide biomarkers.â They continue, âWhen excluding potatoes, consumption of fruits and vegetables weighted by pesticide contamination was associated with higher levels of urinary pesticide biomarkers for organophosphate, pyrethroid, and neonicotinoid insecticides.â The NHANES data is derived from a national biomonitoring survey from the U.S. Centers for Disease Control and Prevention (CDC), which collects information about consumption of fruits and vegetables as well as urine samples. Background As the study authors explain: âHundreds of millions of pounds of synthetic pesticide active ingredients are used every year in the United States, and pesticide exposure can occur through food, drinking water, residential proximity to agricultural spraying, household pesticide use, and occupational use. Pesticide […]
Posted in Agriculture, Alternatives/Organics, Azoxystrobin, Biomonitoring, Body Burden, boscalid, Centers for Disease Control and Prevention (CDC), fludioxonil, Imidacloprid, neonicotinoids, organophosphate, Pesticide Mixtures, Pesticide Regulation, Pesticide Residues, pyraclostrobin, pyrethroids, synergistic effects, Synthetic Pyrethroid, thiabendazole | No Comments »
15
Aug
(Beyond Pesticides, August 15, 2025) In analyzing the data present in an article in Data in Brief, concerning levels of pesticide biomarkers are present in the urine of adolescents and young adults that are linked to numerous health implications. The biomonitoring data, collected at two time points from participants in a longitudinal cohort study in the agricultural county of Pedro Moncayo, Ecuador, encompasses a total of 23 compounds used as herbicides, insecticides, and fungicides and their associated metabolites (breakdown products), which include organophosphates, pyrethroids, and neonicotinoids. The results highlight the disproportionate risks to a Latin American population that occur as a result of living in areas with heavy chemical-intensive agriculture. âThis article presents urinary pesticide metabolite concentrations for 665 participants in the âStudy of Secondary Exposure to Pesticides among Children, Adolescents, and Adultsâ (ESPINA), which were collected during two follow-up assessments,â the authors describe. The first sampling period from July to October 2016, referred to as Follow-up Year [FUY]-8b, includes 529 of the participants, while the second sampling period from July to September 2022 (FUY-14a) includes 505 of the participants. All participants are within the agricultural community of Pedro Moncayo. As the authors note, âThe ESPINA study aimed to include […]
Posted in 2,4-D, acetamiprid, Agriculture, Biomonitoring, Children, Chlorpyrifos, Clothianidin, Cyfluthrin, cypermethrin, DEET, Deltamethrin, Diazinon, fenpropathrin, Flumethrin, flupyradifurone, Glyphosate, Imidacloprid, International, lambda-cyhalothrin, Malathion, mancozeb, Maneb, Metabolites, neonicotinoids, Occupational Health, organophosphate, Parathion, Permethrin, pyrethroids, Repellent, Sulfoxaflor, Synthetic Pyrethroid, Synthetic Pyrethroids, thiacloprid, Thiamethoxam, tralomethrin | No Comments »
14
Aug
(Beyond Pesticides, August 14, 2025) A review in Clinical and Experimental Obstetrics & Gynecology links various classes of environmental pollutants including pesticides and per- and polyfluoroalkyl substances (PFAS), both of which Beyond Pesticides has extensively covered, to adverse effects on the female reproductive system and common mechanisms of toxicity. These chemicals âdisrupt the hypothalamic-pituitary-gonadal axis (HPG), impair ovarian function, and contribute to reproductive dysfunction through mechanisms such as oxidative stress, hormonal disruption, and epigenetic [gene expression or behavior] modifications,â the authors say. This leads to menstrual irregularities, infertility, and pregnancy complications, as well as increases in the risk of reproductive system disorders such as endometriosis, polycystic ovary syndrome (PCOS), and ovarian cancer, among others. âAdditionally, transgenerational effects mediated by epigenetic modifications, germ cell damage, and placental transfer may adversely affect offspring health, increasing the risk of reproductive dysfunction, neurodevelopmental disorders, metabolic diseases, and cancer,â the researchers explain. This study, integrating recent epidemiological and experimental findings, provides an overview of major chemical classes that threaten womenâs health and highlights the need for immediate action. As the authors point out, female reproductive health is important not only for those who choose to plan for a family but also for the overall well-being […]
Posted in Birth defects, Cancer, contamination, Developmental Disorders, DNA Damage, Endocrine Disruption, Epigenetic, Glyphosate, Infertility, Miscarriage, multi-generational effects, organochlorines, organophosphate, Oxidative Stress, PCOS, Reproductive Health, synergistic effects, Women's Health | No Comments »
07
Aug
(Beyond Pesticides, August 7, 2025) The novel study published in Arthritis & Rheumatology is the largest investigation of rheumatoid arthritis (RA) in women to date, finding evidence of heightened risks when exposed to insecticides through data collected from over 400 eligible women in the Agricultural Health Study (AHS). AHS participants include a cohort of thousands of licensed pesticide applicators and their spouses from Iowa and North Carolina, with this particular study as the first to consider the link between pesticide exposure and RA as it affects womenâs health.  âGrowing evidence suggests farming and agricultural pesticide use may be associated with rheumatoid arthritis (RA), but few studies have examined specific pesticides and RA among farm women, who may personally use pesticides or be indirectly exposed,â the study authors explain. The findings reveal that organochlorine insecticides that continue to persist in the environment, as well as organophosphate and synthetic pyrethroid pesticides used in public health or residential settings, correlate with RA diagnoses in women. As shared in previous Daily News, for the most part organochlorine pesticides, including dichlorodiphenyltrichloroethane (DDT), are no longer used worldwide, but the legacy of their poisoning and contamination persists. These compounds are primarily made up of chlorine atoms, […]
Posted in Agriculture, Alternatives/Organics, Arthritis/Joint Inflammation, Carbamates, Carbaryl, Carbofuran, Coumaphos, DDT, Fungicides, Lindane, Malathion, mancozeb, Maneb, Metalaxyl, organochlorines, organophosphate, Permethrin, pyrethroids, Rheumatoid arthritis, Synthetic Pyrethroid, Women's Health | No Comments »
25
Jul
(Beyond Pesticides, July 25, 2025) The scientific literature shows that microplastics (MPs) and pesticides, both ubiquitous throughout the environment, have synergistic effects that threaten aquatic organisms. This means the combined toxicity of the two substances is greater than the sum of two individual exposures. The most recent study to demonstrate this, published in Ecotoxicology, focuses on the impacts of MPs and chlorpyrifos (CPF), a widely used organophosphate insecticide, on cladocerans, a group of microcrustaceans. As Beyond Pesticides has previously reported, microplastics are found in all environments and threaten not only human health but all wildlife in both aquatic and terrestrial ecosystems. The universal distribution of plastics means that they cannot be avoided. Humans and other organisms take up plastics in the form of microparticles and nanoparticles by inhalation, ingestion, and skin contact every day. Microplastics are about the width of a human hair; nanoplastics are much smaller, about twice the width of a DNA strand. Larger pieces of plastic are ground down to these tiny sizes by weathering, temperature, biological processes, and chemical conditions. (See additional Daily News coverage on the health and environmental hazards of plastics here, here, and here.) The authors of the current study, in exposing two […]
Posted in Aquatic Organisms, Biodiversity, Chlorpyrifos, National Organic Standards Board/National Organic Program, organophosphate, Plastic, Reproductive Health, synergistic effects, Water, Wildlife/Endangered Sp. | No Comments »
15
Jul
(Beyond Pesticides, July 15, 2025) A study published in Environmental Science and Technology finds that there are 47 current-use pesticidesâproducts with active ingredients that are currently registered with U.S. Environmental Protection Agency (EPA) âdetected in samples of indoor dust, drinking water, and urine from households in Indiana. This study builds on existing scientific literature documenting the public health threat of nonoccupational, indoor pesticide exposure. (See previous Daily News here, here, and here.) The study is a reminder that pesticides move into the indoor environment through the air, and on clothing, making exposure more widespread than the assumptions used in regulatory reviews. Background and Methodology âIn this study, we collected matched samples of indoor dust, drinking water, and urine from 81 households in Indiana, United States, and analyzed these samples for 82 CUPs [current use pesticides], including 48 insecticides, 25 herbicides, and 9 fungicides,â say the authors. They continue: âOf these, 47 CUPs were identified across samples of indoor dust, drinking water, and urine with median total CUP (âCUP) concentrations of 18 300 ng/g, 101 ng/L, and 2.93 ng/mL, respectively.â The herbicides (13) detected include 2,4-D (2,4-dichlorophenoxyacetic acid), Alachlor, Atrazine, CIAT (Desethyl-atrazine), Diuron, Metolachlor, Metolachlor OA (Oxanilic acid), OIAT (2-Hydroxy-4-isopropylamino-6-amino-s-triazine), OIET […]
Posted in 2,4-D, acetamiprid, Acetochlor, Alachlor, Atrazine, Clothianidin, Diazinon, dinotefuron, Diuron, Fipronil, Fungicides, Herbicides, Household Use, Imidacloprid, Indiana, Indoor Air Quality, Malathion, Metolachlor, Myclobutanil, neonicotinoids, organophosphate, Prometon, Propiconazole, pyrethroids, simazine, State/Local, tebuconazole, thiacloprid, Thiamethoxam, Uncategorized | No Comments »
07
Feb
(Beyond Pesticides, February 7, 2025) With the strong associations established in epidemiologic studies and a dearth of evidence on the actual mechanisms by which pesticides inflict their damage on the brain, a new meta-analysis identifies studies that pesticides can overwhelm cellsâ defenses against them, interfere with cell communication in the brain, and disrupt the epigenetic (gene function) regulation of gene expression. In the journal Nucleus, Bilal Ahmad Mir, PhD and colleagues at the University of Kashmir in Srinagar, India, review what is known at the molecular level about pesticidesâ role in brain cancer. Brain cancer is a heavy burden for its victims and their families, and attributing a cause is, as with many diseases, fraught with difficulty. But there are strong clues: For example, farming is a known risk factor. In a 2021 meta-analysis of epidemiologic studies between 1998 and 2019, analyzed here by Beyond Pesticides, farming was associated with a 13% increase in the risk of brain cancer. For farmers whose specific exposure to pesticides was documented in the studies, the increase jumped to 20 percent. So there is some reason to point a finger at synthetic chemicals. But agricultural workers are not the only ones at risk. According […]
Posted in Agriculture, Brain Effects, Cancer, Chlorpyrifos, Epigenetic, organochlorines, organophosphate, Paraquat, Pyrethrin, pyrethroids, Uncategorized | No Comments »
06
Feb
(Beyond Pesticides, February 6, 2025) Months after publishing a June 2024 study regarding concentrations of pesticides discovered in legal (and illegal) cannabis products in California, the Los Angeles Times has released a follow-up exposĂŠ highlighting extensive pesticide contamination, including from âhiddenâ pesticides that regulators have not monitored. The authors conclude that in Californiaâs legal weed market, over half of available smoking products are found to contain hidden chemicalsâtoxic pesticides present in products but not regulated or monitored by state authorities. Since 2015, Beyond Pesticides has laid out health, safety, and environmental concerns related to the contamination of cannabis by pesticides (and fertilizers) alongside an imperative need to mandate an organic systems approach to cannabis production. Yet ten years later, it appears nationally that California state regulators are alone in moving forward in 2021 with state organic cannabis certification. There are other marketplace-based cannabis certification labels that require comparable organic certification practices (see Beyond Pesticides reporting here and here). For more information, please see past Pesticides and You reporting here and here. The Los Angeles Times analyzed the results from state licensed laboratory testing of more than 370 legal cannabis products, representing 86 brands. In addition to the 66 chemicals required […]
Posted in Acephate, Agriculture, Alternatives/Organics, and Rodenticide Act (FIFRA), Bifenthrin, California, Cannabis, chlorfenapyr, contamination, Fungicides, Integrated and Organic Pest Management, National Organic Standards Board/National Organic Program, organophosphate, Pesticide Regulation, pymetrozine, trifloxystrobin, Uncategorized | 1 Comment »
15
Jan
(Beyond Pesticides, January 15, 2025) There is robust scientific literature that unpacks the adverse human health effects of pesticide exposure, however immunological impacts do not receive adequate attention in regulatory review processes, according to an in-depth literature review. In a piece published in Frontiers in Immunology (2024) critiquing recent peer-reviewed scientific studies, as well as unpublished research produced by the Institute of Biology and Experimental Medicine in partnership with the National Scientific and Technical Research Council in Argentina, researchers assess immune system effects of pesticide exposure, which creates the conditions for deadly health conditions including various forms of cancer. The focus of this study, according to the authors, is âto critically review fundamental aspects of toxicological studies conducted on PPPs [Plant Protection Products] to provide a clearer understanding of the risks associated with exposure to these compounds on human health.â PPPs are pesticide products that contain more than one active ingredient, and can include synergistic ingredients that supercharge them alongside inert ingredients that pesticide companies are not legally required to disclose under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), but are often manipulated biologically and chemically active. Most studies analyze the toxicological impacts of active ingredients in isolation rather […]
Posted in Bayer, Cancer, Chemical Mixtures, Chlorpyrifos, Environmental Protection Agency (EPA), Glyphosate, Immunotoxicity, organophosphate, Pesticide Regulation, Uncategorized | No Comments »