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Daily News Blog

Archive for the 'phthalates' Category


12
Aug

Endocrine Disrupting Chemicals Contribute to Liver Injury, including Toxic PFAS and Pesticides

(Beyond Pesticides, August 12, 2022) Gestational (during pregnancy) exposure to endocrine disrupting chemicals (EDCs) like pesticides, per- and polyfluoroalkyl substances (PFAS), among others, may increase pediatric (child) liver injury and non-alcoholic fatty liver disease (NAFLD) risk, according to a study published in Environmental Health. Past studies associate exposure to EDCs with increased susceptibility to adverse health effects during critical fetal and childhood developmental periods. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Endocrine disruption can lead to several health problems, including hormone-related cancer development (i.e., thyroid, breast, ovarian, prostate, testicular), reproductive dysfunction, and diabetes/obesity that can span generations. Because EDCs are ubiquitous because they are found in many products, studies report that these toxic chemical compounds are detectable in infants, children, and pregnant women. Furthermore, pregnant women can readily transfer compounds to the developing fetus through the placenta. Therefore, it is essential to understand the mechanism behind how harmful chemical exposure induces endocrine disruption during critical developmental periods. Researchers note, “Considering the lack of studies on endocrine disruption and pediatric NAFLD, research like this highlights the need to understand the underlying […]

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30
Jun

Implications for Human Health: Pesticides and Other Environmental Contaminants Alter Gut Microbiome

(Beyond Pesticides, June 30, 2020) A review of scientific literature on the toxic effect of environmental contaminants—including pesticides—published in the journal Toxicological Science, “The Impact of Environmental Chemicals on the Gut Microbiome,” associates these chemicals to changes in the gut microbiome and other adverse health implications. The review, by researchers at the University of Illinois, looks at how environmental contaminants adversely effects and reinforce chemical disruption of the gut microbiome. It highlights the importance of evaluating how environmental contaminants, like pesticides, impact body regulation by gut microbiota. The study has significant implications for considerations that should be, but are not currently, a part of pesticide review and registration by the U.S. Environmental Protection Agency (EPA). Gut microbiota plays a crucial role in lifelong digestion, immune, and central nervous system regulation, as wells as other bodily functions. Through the gut biome, pesticide exposure can enhance or exacerbate, the adverse effects of additional environmental toxicants on the body. Since the gut microbiome shapes metabolism, it can mediate some toxic effects of environmental chemicals. However, with prolonged exposure to various environmental contaminants, critical chemical-induced changes may occur in the gut microbes, influencing adverse health outcomes. Karen Chiu, Ph.D., a graduate research fellow at the […]

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24
Oct

Dolphins in Gulf of Mexico Contaminated with “Inert,” but Toxic, Pesticide Product Ingredients

(Beyond Pesticides, October 24, 2018) Bottlenose dolphins found along Florida’s west coast contain detectable levels of phthalates, chemicals used in plastics, cosmetics and as inert ingredients in pesticide products, research published in the journal GeoHealth last month indicates. The study, published by scientists from the College of Charleston, South Carolina, is the first to find detectable levels of these toxic industrial byproducts in dolphins. Given the transient nature of urinary detection, the findings indicate that dolphins and other marine mammals are at increased risk of health effects related to phthalate exposure. Scientists sampled a total of 17 dolphins found in Sarasota Bay, FL over the course of two years. Of the 17, phthalates were detected in 12 individuals, or 71% of dolphins. The type of phthalates discovered was indicative of the source of the contaminant. With researchers detecting mono‐(2‐ethylhexyl) phthalate (MEHP) and monoethyl phthalate (MEP) most frequently. While MEHP is associated with plastic pollution, MEP is a breakdown product of diethyl phthalate (DEP), a compound that has been used in pesticide products as an inert ingredient. “These chemicals can enter marine waters from urban runoff and agriculture or industrial emissions, but we also know that there is a lot of […]

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