Archive for the 'Pesticide Mixtures' Category
28
Apr
(Beyond Pesticides, April 28, 2026) In Chemical Research in Toxicology, researchers from the Universitat Rovira i Virgili in Catalonia, Spain highlight the threats to human and environmental health with “combined exposures to multiple chemical toxicants, including industrial chemicals, heavy metals, pesticides, endocrine-disrupting chemicals (EDCs), and per- and polyfluoroalkyl substances (PFAS).” As these compounds are encountered in mixtures in real-world settings, the resulting interaction can have additive or synergistic effects that risk assessments fail to adequately capture. As the authors point out: “This leads to a systematic underestimation of health risks, particularly for vulnerable populations. Despite robust evidence on mixture toxicity, major regulatory frameworks such as the U.S. Toxic Substances Control Act (TSCA) and the EU’s [European Union] REACH program continue to assess chemicals in isolation.” Importance and Background Environmental toxicants are ubiquitous throughout nature and within all organisms. In humans, these compounds can accumulate, referred to as ‘Body Burden’, which encompasses numerous chemicals such as pesticide mixtures. “Critically, organisms are rarely exposed to a single chemical in isolation,” the researchers note. “Rather, they continuously encounter complex mixtures of contaminants whose combined effects may differ substantially from those predicted by examining each substance individually.” As the authors explain, regulatory agencies underestimate […]
Posted in Agriculture, Alternatives/Organics, Biodiversity, Body Burden, Chemical Mixtures, Endocrine Disruption, Environmental Protection Agency (EPA), European Union, Pesticide Mixtures, Pesticide Regulation, PFAS, synergistic effects | No Comments »
24
Apr
(Beyond Pesticides, April 24, 2026) In a review of scientific literature documenting pesticide contamination in the atmosphere, international researchers find human and ecosystem exposure even in remote and distant areas. As published in the Journal of Hazardous Materials, the authors state: “Atmospheric transport of pesticides is a globally significant yet widely underestimated driver of human and ecological exposure, with contamination documented far beyond treated fields. This review provides a novel integrated synthesis, bridging emission pathways, atmospheric transformation processes, monitoring evidence, model limitations, and regulatory gaps to deliver a comprehensive understanding of the fate and impacts of pesticides in the atmosphere.” In analyzing the current knowledge on pesticide emissions, through both drift and volatilization (process where a solid or liquid converts into a gas or vapor), the researchers highlight “the widespread detection of both current-use and banned pesticides in environmental matrices far from their application,” along with the resulting implications for human health and environmental health. As the current risk assessment framework “fails to adequately address the perturbations caused by the atmospheric transport of pesticides,” the urgent need to transition away from chemical-intensive practices grows stronger. Background While this review highlights regulatory gaps in the European Union (EU), the cited scientific […]
Posted in Agriculture, air pollution, Chemical Mixtures, contamination, Disease/Health Effects, Drift, European Union, Pesticide Drift, Pesticide Mixtures, Pesticide Regulation, Pesticide Residues | No Comments »
22
Apr
Editor’s Note: The board and staff at Beyond Pesticides wish you a Happy Earth Day 2026! Click here or the banner below to honor today, a day of education and action that embodies the power of people in their communities engaging to advance changes in policies and practices that meet the environmental and public health challenges of the day! (Beyond Pesticides, April 22, 2026) A study of the effects of flooding on aquatic-terrestrial pesticide transfer, published in Archives of Environmental Contamination and Toxicology, finds heightened risks to riparian zone ecosystems as flooding frequency continues to increase with climate change. Riparian zones, recognized as biodiversity hotspots, “are increasingly subjected to various stressors, including chemical contaminants such as pesticides,” the authors state. As transportation of these compounds can occur not only through surface runoff but through flooding events, the frequency and duration of floods can greatly impact the cumulative effects of pesticides on soil health and organisms within ecosystems. In analyzing pesticide residues following simulated flooding within a controlled experiment, the researchers find: “[S]ix pesticides were detected exclusively in riparian root-zone soil following four repeated flooding events. Our findings indicate that both longer flood durations and repeated flooding events tend to increase […]
Posted in acetamiprid, Agriculture, Aquatic Organisms, Azoxystrobin, Beneficials, Biodiversity, boscalid, Climate, Climate Change, contamination, Earth Day, Ecosystem Services, fluopyram, Germany, Metalaxyl, Metolachlor, Pesticide Drift, Pesticide Mixtures, Pesticide Residues, soil health, spiroxamine, Water, Wildlife/Endangered Sp. | No Comments »
15
Apr
(Beyond Pesticides, April 15, 2026) Researchers in the Czech Republic tested indoor dust across 116 homes and found that 93 percent of homes across urban and rural areas contained residue of at least one current-use pesticide (CUP). The study also found in every household residues of hexachlorobenzene (HCB) and pentachlorobenzene (PeCB), the breakdown products or byproducts of certain banned organochlorine pesticides (OCP). These compounds, as well as DDT metabolites DDE and DDD, were detected in more than half of the homes tested. Results in this study and previous research confirm that pesticides used outdoors find their way indoors, resulting in an exposure pattern that is not calculated when pesticides are registered and allowed on the market. The findings are published in Indoor Environments. These findings characterize the legacy of toxic pesticide exposure resulting from the proliferation of pesticides in the United States and around the world without a complete assessment of the chemicals’ residual activity and multigenerational adverse impacts on health. Based on the decades of peer-reviewed scientific literature on pesticide exposure and effects from across the globe, public health and environmental advocates warn that there is a continuation of this pattern of long-term effects associated with new pesticides linked […]
Posted in Acetochlor, Alachlor, Atrazine, Azinphos-methyl, Carbaryl, Carbendazim, Chemical Mixtures, Chemicals, Chlorpyrifos, Diazinon, Dimethoate, Diuron, Household Use, Indoor Air Quality, Malathion, metazachlor, Metolachlor, Parathion, Pendimethalin, Pesticide Drift, Pesticide Mixtures, pirimicarb, Propiconazole, simazine, tebuconazole, terbufos, Uncategorized | No Comments »
14
Apr
(Beyond Pesticides, April 14, 2026) A novel study mapping pesticide mixtures and cancer risk, published in Nature Health, “reveals a robust spatial association between environmental pesticide exposure risk and cancer incidence.” The team of international researchers incorporates pesticide risk modeling with Peruvian National Cancer Institute (INEN) registry data to map pesticide-induced cancer clusters in Peru, finding significant associations between pesticide mixtures and cases of carcinogenicity. The study analyzes 31 active ingredients to identify pesticide-associated cancer hotspots, none of which are classified as carcinogenic on their own by international standards. When combined as pesticide mixtures, as experienced in real-world environments, heightened risks and synergistic effects are noted. “Collectively, these findings strongly support a mechanistic [causal] link between pesticide exposure and cancer, challenging assumptions of human non-carcinogenicity derived from reductionist experimental models,” the authors state. “This study redefines the exposome [measure of all environmental, dietary, lifestyle, and social exposures of an individual] as a lineage-conditioned, mechanistically tractable framework and shows how complex pesticide mixtures can contribute to carcinogenic trajectories, with profound and far-reaching implications for global health policy and socio-ecological equity.” Background An extensive body of scientific literature connects individual pesticide active ingredients to a wide array of health and environmental effects […]
Posted in Agriculture, Body Burden, Cancer, Peru, Pesticide Drift, Pesticide Mixtures, Pesticide Residues, synergistic effects | No Comments »
01
Apr
(Beyond Pesticides, April 1, 2026) Researchers at the University of Washington and members of the Washington State Liquor and Cannabis Board published a commentary piece in Clinical Therapeutics highlighting the growing inadequacy of state-level regulatory safeguards for pesticide contamination of cannabis products. The Environmental Protection Agency (EPA) is unable to assess pesticide residues, nor is it permitted to set tolerance limits under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), because, according to the Controlled Substances Act (CSA), cannabis is a Schedule 1 narcotic, meaning there is “no accepted medical use.” As a result, EPA cannot conduct a full assessment of pesticide exposure associated with inhalation, ingestion, and dermal (skin) adsorption. There is an ongoing rescheduling process that was proposed in 2024 and followed up with an executive order in late 2025 to transition cannabis toward Schedule III status, suggesting that there would be an opening for EPA to promulgate rulemaking to support state-level regulations if it were to move forward. An analysis of active legislation in state legislatures for the 2026 session highlights the concerns—at least 14 states (including Connecticut, California, Georgia, Hawai’i, Illinois, Iowa, Kansas, Kentucky, Maine, New Hampshire, Oklahoma, Virginia, West Virginia, and Wisconsin) had bills to […]
Posted in Cannabis, Disease/Health Effects, Food and Drug Administration (FDA), Pesticide Mixtures, Pesticide Regulation, US Department of Agriculture (USDA) | No Comments »
13
Mar
(Beyond Pesticides, March 13, 2026) In a press release on March 10, 2026, Public Employees for Environmental Responsibility (PEER) cites independent test data on the herbicide indaziflam with detections of per- and poly-fluoroalkyl substances (PFAS), the “forever chemicals” known for significant toxicity at low level exposure and high persistence. The product, Rejuvra™, is produced by Envu (a former division of Bayer) and “is being sprayed and considered for use across millions of acres of Bureau of Land Management (BLM) and US Forest Service land.” Scientific literature connects indaziflam and PFAS with adverse effects to human, soil, and biodiversity health, raising serious concerns about their wide use in agriculture and general land management of lawns, parks, playing fields, ornamentals, fence lines, rights-of-way, rangeland, open space, and Christmas trees. Background As a pre-emergent weed killer used to kill annual grasses and unwanted broadleaf plants, the fluoroalkyltriazine herbicide is broadly labeled for use in residential areas, commercial ornamental and sod production, forestry, and mostly orchard crops. While indaziflam is considered a “selective” herbicide, it actually kills and prevents germination of a wide range of broad-leaved plants and grasses and comes close to being a soil sterilant.  Since the chemical is subject to drift […]
Posted in Bayer, Biodiversity, Chemical Mixtures, contamination, Ecosystem Services, Environmental Protection Agency (EPA), Forestry, Herbicides, indaziflam, Pesticide Mixtures, PFAS, Wildlife/Endangered Sp. | No Comments »
12
Mar
(Beyond Pesticides, March 12, 2026) The science connecting pesticide exposure to neurotoxicity continues to mount. A study in Discover Toxicology highlights neurotoxic pollutants as significant environmental threats, showcasing the adverse impacts on vertebrates’ neurological health from pesticides, including organophosphates, carbamates, and organochlorines. “These substances disrupt normal neurophysiological functions by impairing neurotransmission, generating oxidative stress, provoking neuroinflammation, and initiating neuronal cell death,” the authors say. They continue, “Such disturbances are linked to cognitive deficits, motor impairments, and abnormal neural development.” Neurological conditions can manifest as headaches, muscle weakness, tremors, paralysis, coordination challenges, vision loss, hallucinations, vertigo, seizures, memory loss, slurred speech, trouble breathing with minimal exertion, and more. The range of adverse effects from low-dose, long-term exposure and low-dose (or subchronic) exposure during developmental phases of life raises serious questions about the adequacy of the regulatory review of pesticides, which focuses on acute high and lethal dose exposure. One study on the neurotoxicity of pesticides, published in Chemosphere, concludes, “New regulatory and preventive measures to mitigate the neurotoxic effects of pesticides are needed.” (See also Daily News.) Even at low concentration, chronic exposure to pesticides and other environmental contaminants “poses serious ecological and health concerns” that occur as these chemicals “bioaccumulate […]
Posted in Alzheimers's, Aquatic Organisms, Atrazine, behavioral and cognitive effects, Beneficials, Biodiversity, Brain Effects, Carbamates, Carbaryl, Developmental Disorders, DNA Damage, Glyphosate, Nervous System Effects, organochlorines, organophosphate, Oxidative Stress, Paraquat, Parkinson's, Pesticide Mixtures, Pesticide Regulation, PFAS, synergistic effects, Wildlife/Endangered Sp. | No Comments »
18
Feb
(Beyond Pesticides, February 18, 2026) Research finds that widespread agricultural pesticide use increases chronic dietary exposure in poultry and leads to adverse reproductive effects, despite meeting legal residue limits. As published in Poultry Science by researchers in Poland, the study analyzes low-dose exposure of roosters (Gallus gallus domesticus) to the fungicide tebuconazole (TEB), the insecticide imidacloprid (IMI), and the weed killer glyphosate (GLP) individually and in mixtures, with all concentrations at or below the maximum residue limits (MRLs) established by the European Union (EU). “Sub-MRL pesticide exposure impaired male reproductive function, with the most pronounced effects observed following combined treatments,” the authors report. They continue: “[E]xposure resulted in reduced semen quality, decreased fertility and hatchability, and increased embryo mortality, particularly in groups receiving IMI alone or in combination. These functional impairments were accompanied by detectable pesticide residues in reproductive tissues and body fluids, as well as modulation [modification/alteration] of local and systemic immune parameters.” The results of the experiment highlight how combined pesticide exposure, resulting from common use of multiple pesticide active ingredients concurrently, produces “stronger and more persistent reproductive effects than individual compounds, indicating mixture-specific toxicity.” This study is particularly important, as it represents the chronic exposure to MRL-compliant […]
Posted in Agriculture, Biomonitoring, Birds, Chemical Mixtures, contamination, European Union, Fungicides, Glyphosate, Herbicides, Imidacloprid, Insecticides, Livestock, Pesticide Mixtures, Pesticide Residues, Reproductive Health, synergistic effects, tebuconazole | No Comments »
12
Feb
(Beyond Pesticides, February 12, 2026) Editor’s Note. This is a piece about improving risk assessments and a proposal that could offer a more realistic characterization of the harm associated with the complexities of pesticide exposure. Beyond Pesticides notes that risk assessment methodology, unless it is considered in the context of a rigorous alternatives assessment, begins with the mostly false assumption that petrochemical pesticides are needed (or are essential) to achieve cost-effective pest management, agricultural productivity and profitability, and quality of life, when, in fact, this is not the case. Therefore, improved risk calculations—as the article being reviewed here proposes—while important to characterizing the harm and the unknown adverse effects associated with pesticide use, still impose some level of harm deemed by the government to be acceptable. Even worse, the adverse effects of exposure cannot be fully characterized because of uncertainties or a lack of data on harmful endpoints, as is the case currently with endocrine-disrupting pesticides not fully evaluated by the U.S. Environmental Protection Agency (EPA), California’s Department of Pesticide Regulation (DPR), or other regulatory bodies. These pesticides are known to induce cancer, reproductive harm, infertility, biodiversity decline, and other life-threatening, often multigenerational, effects. The authors do recognize the serious […]
Posted in California, Environmental Protection Agency (EPA), Pesticide Drift, Pesticide Mixtures, Pesticide Regulation, Pesticide Residues, Uncategorized | No Comments »
21
Jan
(Beyond Pesticides, January 21, 2026) The data in the annual U.S. Department of Agriculture (USDA) pesticide residue report, released earlier this month, continues to show a pattern of pesticide residues in the majority of food tested by the U.S. Department of Agriculture (USDA). Health advocates say low-level pesticide residues in the food supply within legal limits raise serious hazard concerns, while USDA, in its Pesticide Data Program–Annual Summary, Calendar Year 2024, points to controversial residue standards as a measure of safety. The USDA report finds that over 57 percent of tested commodities contain at least one pesticide and that less than one percent of detected residues violate the legal limit set as a tolerance by the U.S. Environmental Protection Agency (EPA). Residues allowed under tolerances establish allowable pesticide use patterns in agriculture that, beyond dietary risks, result in exposure to farmworkers, farmers, waterways, wildlife, and the broad ecosystem in which they are used. (See Eating with a Conscience for a list of pesticides allowed in food production by commodity.) With respect to the preponderance of evidence on adverse health and ecological effects of cumulative exposure to toxic agrichemicals, including pesticides, Beyond Pesticides has called for the transition to organic agriculture. […]
Posted in Acephate, Agriculture, Chemical Mixtures, cypermethrin, Deltamethrin, lambda-cyhalothrin, Methomyl, Myclobutanil, Permethrin, Pesticide Mixtures, Uncategorized, US Department of Agriculture (USDA) | No Comments »
02
Jan
(Beyond Pesticides, January 2, 2026) Texas-based pecan orchard Swift River Pecans is collaborating with local conservation nonprofit Merlin Tuttle’s Bat Conservation “so they could collect more information on the species that visit his 266-acre property, and to show off the bats’ value to his operation,” according to recent coverage by NPR affiliate KCUR. “Bats love to munch on insects like stink bugs and moths. Some farmers are now relying on the mammals for pest control – and ditching chemicals,” says Michael Marks, reporter for NPR (Harvest Public Media) and Texas Standard. The orchard operator and nonprofit have been collaborating since 2004, after Troy Swift (orchard owner) employed a chemical-intensive approach since purchasing the land in 1988. Merlin Tuttle, “an ecologist and conservationist who has spent 65 years studying bats around the globe,” has been setting up bat boxes using cypress trees from a lumber mill on-site—the researcher has opted for this wood type because it is porous and regulates temperature appropriately. “Our job is to work with Mother Nature instead of against her to make the best pecans money can buy. That’s the way we see it,” says Mr. Swift, who also serves as the president of the Texas Pecan […]
Posted in Alternatives/Organics, Bats, Biodiversity, Climate, Ecosystem Services, Fungicides, Herbicides, Insecticides, Pesticide Drift, Pesticide Mixtures, Uncategorized | No Comments »
03
Dec
(Beyond Pesticides, December 3, 2025) Childhood cancers are on the rise globally; in the U.S. cancer is the second most common cause of death in children between one and 14 years old, and the fourth most common in adolescents. A recent study of Nebraska pesticide use and pediatric cancer incidence by researchers from the University of Nebraska Medical Center and the University of Idaho Department of Fish and Wildlife Sciences found positive associations between pesticides and overall cancer, brain and central nervous system cancers, and leukemia among children (defined as under age 20). The study’s lead author, Jabeen Taiba, PhD, of the University of Nebraska Medical Center, will discuss the study results on December 4, 2025, at the second session of Beyond Pesticides’ 42nd National Pesticide Forum, The Pesticide Threat to Environmental Health – Advancing Holistic Solutions Aligned with Nature. The first session recordings and materials are available here. The authors’ emphasis on evaluating mixtures, and their innovative technical methods for doing so, highlight the direction environmental health research and regulation must take. Studying pesticides singly is an inadequate approach, according to the authors, because pesticides are not applied individually anymore, but very often in mixtures of herbicides, insecticides, and […]
Posted in Agriculture, California, Cancer, Children, Dicamba, Farmworkers, Glyphosate, Paraquat, Pesticide Mixtures, quizalofop, tefluthrin, triasulfuron, Uncategorized | No Comments »
30
Oct
(Beyond Pesticides, October 29, 2025) A study published in Environment International evaluates residues of individual and mixtures of endocrine-disrupting chemicals (EDCs), including pesticides, and finds an association between exposure and hyperactive behavior in children. The researchers evaluated urine samples from over 800 preschoolers, identifying and statistically analyzing concentrations of 22 EDCs, and finding that nine of these chemicals are significantly associated with hyperactivity trajectories and EDC mixtures are positively associated with hyperactive behavior, noting the strongest association in girls. “The current study indicates the adverse health effects of exposure to mixtures of EDCs among preschoolers, and suggests gender specificity in these effects,” the researchers state. They continue, “This highlights the importance of focusing on multi-pollutant exposure in early childhood.” Study Importance “Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children, which has become one of the main factors leading to the burden of disease in children and adolescents worldwide.” The authors continue: “Its core symptoms are high levels of inattention and/or hyperactivity/impulsivity during the preschool period. A meta-analysis showed that the overall prevalence of ADHD in children in China over the past 15 years was as high as 6.2%, and has been increasing over recent years.” In comparison, according […]
Posted in ADHD, Biomonitoring, Body Burden, Chemical Mixtures, Children, Children/Schools, Endocrine Disruption, Pesticide Mixtures, PFAS | No Comments »
21
Oct
(Beyond Pesticides, October 21, 2025) A study, published in International Journal of Hygiene and Environmental Health, calculates cumulative dietary pesticide exposure and finds a significant positive association between pesticide residues in food and urine when analyzing over 40 produce types. The research uses data for 1,837 individuals from the 2015–2016 National Health and Nutrition Examination Survey (NHANES) and compares them to biomonitoring samples of the participants. According to the researchers, “Here we show that consumption of fruits and vegetables, weighted by pesticide load, is associated with increasing levels of urinary pesticide biomarkers.” They continue, “When excluding potatoes, consumption of fruits and vegetables weighted by pesticide contamination was associated with higher levels of urinary pesticide biomarkers for organophosphate, pyrethroid, and neonicotinoid insecticides.” The NHANES data is derived from a national biomonitoring survey from the U.S. Centers for Disease Control and Prevention (CDC), which collects information about consumption of fruits and vegetables as well as urine samples. Background As the study authors explain: “Hundreds of millions of pounds of synthetic pesticide active ingredients are used every year in the United States, and pesticide exposure can occur through food, drinking water, residential proximity to agricultural spraying, household pesticide use, and occupational use. Pesticide […]
Posted in Agriculture, Alternatives/Organics, Azoxystrobin, Biomonitoring, Body Burden, boscalid, Centers for Disease Control and Prevention (CDC), fludioxonil, Imidacloprid, neonicotinoids, organophosphate, Pesticide Mixtures, Pesticide Regulation, Pesticide Residues, pyraclostrobin, pyrethroids, synergistic effects, Synthetic Pyrethroid, thiabendazole | No Comments »
15
Oct
(Beyond Pesticides, October 15, 2025) The latest Scientific Investigations Report for 2025 from the U.S. Geological Survey (USGS), entitled “National Water Quality Program: Multidecadal Change in Pesticide Concentrations Relative to Human Health Benchmarks in the Nation’s Groundwater,” finds moderate concentrations of five pesticides, with the highest percentages in agricultural wells, and concentrations of the carcinogenic soil fumigant DBCP (1,2-dibromo-3-chloropropane), which also causes infertility, that are greater than the maximum containment level, despite being banned over 45 years ago. These results highlight the persistence of pesticides used in agriculture and the elevated risks of pesticide contamination in agricultural areas. This report monitors concentrations of pesticides in well networks across the U.S. in decadal intervals, with this last one incorporating data ranging from 1993-2023. Additionally, DBCP in one well network in the San Joaquin-Tulare River Basin in California continues to be assessed due to previous levels exceeding the human health benchmark (HHB) established by the U.S. Environmental Protection Agency (EPA). The limitations of the study are disclosed in the text of the report. As the authors state: “Only pesticides with an HHB were included in the multidecadal pesticide change analysis… The total number of pesticides included in this study is less than […]
Posted in Agriculture, Alachlor, Atrazine, California, contamination, DBCP, deethylatrazine, Drinking Water, Groundwater, Pesticide Mixtures, Prometon, simazine, synergistic effects, U.S. Geological Survey, Water | 1 Comment »
07
Oct
(Beyond Pesticides, October 7, 2025) Published in Environment International, a study utilizing silicone wristbands provides a snapshot of chemical exposure in over 600 participants across 10 European countries. Using the wristbands as passive and noninvasive samplers, the researchers find that organic farmers’ wristbands contain lower pesticide levels than other groups, offering insight into the benefits of organic and disproportionate risks to farmers using chemical-intensive methods. The results further reveal prevalent environmental pesticide mixtures, in addition to highlighting exposure to current-use pesticides (CUPs) and legacy (banned) pesticides that occurs through multiple exposure routes to workers, residents, and consumers. “Our study offers a comprehensive analysis of non-dietary pesticide exposure patterns among various populations across the EU [European Union], underscoring its widespread prevalence and identifying significant occupational and residential predictors,” the authors explain. As pesticide exposure occurs through both dietary and nondietary routes, such as through dermal (skin) contact and inhalation of contaminated air, there “is a growing need for aggregated [total; combined] exposure estimates across occupationally and nonoccupationally exposed populations.” The study includes testing for 193 pesticides, both legacy pesticides and CUPs, captured in silicone wristbands worn by farmers, residents living close to treated fields (neighbors), and the general population (consumers) in […]
Posted in Agriculture, Alternatives/Organics, Biomonitoring, Chlorpyrifos, European Union, Farmworkers, Metabolites, Occupational Health, Permethrin, Pesticide Mixtures | No Comments »
25
Sep
(Beyond Pesticides, September 25, 2025) Reinforcing numerous studies’ findings of widespread environmental contamination with PFAS (per- and polyfluoroalkyl substances), heavy metals, pesticide metabolites, and pharmaceuticals, researchers detected the chemicals in noncommercial backyard eggs laid in Greece, according to a study published in Science of The Total Environment. The researchers found that “[o]nly 9 out of 17 samples were compliant to the limit….set by the [European Union] for the sum of PFHxS [perfluorohexanesulfonic acid], PFOS [perfluorooctanesulfonic acid], PFOA [perfluorooctanoic acid], and PFNA [perfluorononanoic acid].” They continue: “[A]s regards PFOS, PFHxS, and PFNA, seven, six and one out of 17 samples, respectively, were above the ML (maximum limit) as set by the EU.” With current regulatory standards focused on evaluating exposure to individual chemicals and, in some instances, cumulative risk associated with chemicals that have a common mechanism of effect, this study points out the importance of looking at mixtures of chemicals and the potential synergistic effects. There are some fluorinated pesticides defined as PFAS due to their molecular structure and high toxicity, which makes the chemicals highly persistent in the environment. Center for Food Safety, Center for Biological Diversity, and Public Employees for Environmental Responsibility reviewed the full list of active […]
Posted in European Union, Pesticide Drift, Pesticide Mixtures, Pesticide Regulation, PFAS, Uncategorized | No Comments »
17
Sep
(Beyond Pesticides, September 17, 2025) A study in Environmental Science & Technology finds additive effects of a synthetic pyrethroid insecticide (cypermethrin) and two fungicides (azoxystrobin and prochloraz) on biological control, biomass of major invertebrate trophic groups (position in food web), and soil ecosystem processes in arable systems (land suitable for growing crops). The study authors further highlight the failure of pesticide regulations to consider elaborate trophic interactions and pesticide mixtures, as well as additive and synergistic effects within their assessments, calling attention to the complexity of real-world exposures and the lack of research to fully understand the implications of chemical use for agricultural and land management purposes. “Arable systems have a high dependence on diverse natural biota to support pest control, soil bioturbation, and nutrient recycling,” the researchers write. These communities rely on a balance of organisms within various trophic levels in order to function and provide vital ecosystem services. Disruptions caused by environmental contaminants, such as pesticides to nontarget organisms, impact entire ecosystems and overall biodiversity. As the authors state, current risk assessments underestimate the real-world risks of petrochemical pesticides and synthetic fertilizers that, despite a wide body of science connecting exposure to deleterious health and environmental effects, are […]
Posted in Agriculture, Aphids, Azoxystrobin, Beneficials, Biodiversity, Biological Control, cypermethrin, Ecosystem Services, Environmental Protection Agency (EPA), Fungicides, Pesticide Mixtures, synergistic effects, Synthetic Pyrethroid | No Comments »
10
Sep
(Beyond Pesticides, September 10, 2025) After being criticized by the chemical industry and allied agribusiness and service industry groups on the Make America Healthy Again (MAHA) report in May, the strategy document, released yesterday, has tamped down efforts to reform government programs that regulate pesticides. There are no specific recommendations on improving the regulation of pesticides. Rather, the strategy appears to embrace business-as-usual and could even ramp up government efforts to tout the need for pesticides and claims that current regulatory reviews are effective and comprehensive. In a section of the strategy entitled “Increasing Public Awareness and Knowledge,” the document says: “EPA, partnering with food and agricultural stakeholders, will work to ensure that the public has awareness and confidence in EPA’s pesticide robust review procedures and how that relates to the limiting of risk for users and the general public and informs continual improvement.” This is at odds with the earlier MAHA assessment report which identified pesticides as substances of concern that, citing deficiencies in chemical reviews, “may be neglecting potential synergistic effects and cumulative burdens, thereby missing opportunities to translate cumulative risk assessment into the clinical environment in meaningful ways.” While the earlier report, Make Our Children Healthy Again: Assessment, […]
Posted in Agriculture, and Rodenticide Act (FIFRA), Announcements, Atrazine, Chemical Mixtures, Chemicals, Children, Children/Schools, Chlorpyrifos, Clean Water Act, Corporations, Environmental Protection Agency (EPA), Farmworkers, Federal Insecticide, Fungicide, Glyphosate, Groundwater, Label Claims, Pesticide Mixtures, Pesticide Regulation, Reflection, synergistic effects, Uncategorized, US Department of Agriculture (USDA), Water, Water Regulation | No Comments »
10
Sep
(Beyond Pesticides, September 10, 2025) Published earlier this year, a review of over 1,700 studies in Nature Communications finds pesticides affect a diverse range of nontarget organisms and contribute to global biodiversity loss. The authors* reveal “negative responses of the growth, reproduction, behaviour and other physiological biomarkers within terrestrial and aquatic systems” for nontarget plants, animals, and microorganisms. “To our knowledge, there has been no systematic and overarching synthesis of how different types of pesticides affect the diversity of multiple non-target eukaryotic and prokaryotic organisms across all trophic levels,” the researchers write. They continue, “Furthermore, current syntheses have not considered how the impacts of pesticides differ globally across climatic zones or for major mechanisms of exposure, such as those acting in aquatic or terrestrial environments.” In particular, pesticide regulatory risk assessments analyze a limited range of model species, including rats, zebrafish, clawed frogs, honeybees, and earthworms, among others. As such, they are unlikely to capture the variety of responses to pesticide exposure seen across the diversity of species and communities found in both managed and natural systems,” the authors state. *Authors include Beyond Pesticides 2023 National Forum speaker Dave Goulson—see the Daily News on his keynote address here. Research Results […]
Posted in Aquatic Organisms, Beneficials, Biodiversity, DNA Damage, Fungicides, Herbicides, Nervous System Effects, Pesticide Mixtures, synergistic effects, Wildlife/Endangered Sp. | No Comments »
18
Jul
(Beyond Pesticides, July 18, 2025) A study in Royal Society Open Science shows intraspecific differences (between individuals of a species) in wild bumblebees (Bombus vosnesenskii) exposed to an herbicide (glyphosate), a fungicide (tebuconazole), and an insecticide (imidacloprid), with gut microbiome health as a factor. “Wild pollinator declines are increasingly linked to pesticide exposure, yet it is unclear how intraspecific differences contribute to observed variation in sensitivity, and the role gut microbes play in the sensitivity of wild bees is largely unexplored,” the authors explain. “Here, we investigate site-level differences in survival and microbiome structure of a wild bumble bee exposed to multiple pesticides, both individually and in combination.” In collecting 175 individuals of this wild, foraging species from an alpine meadow, a valley lake shoreline, and a suburban park and exposing them to a diet with individual pesticides and mixtures, the researchers assess the varying lethal and sublethal effects that can occur with pesticide exposure. Between the three sites, the survival differences “emphasize the importance of considering population of origin when studying pesticide toxicity of wild bees” and highlight how pesticide sensitivity not only varies between species but within individuals of the same species with site-specific impacts. (See previous Daily […]
Posted in Beneficials, Biodiversity, Ecosystem Services, Glyphosate, Imidacloprid, Microbiome, Nevada, Pesticide Mixtures, Pesticide Regulation, Pollinators, synergistic effects, tebuconazole, Wildlife/Endangered Sp. | No Comments »
24
Jun
(Beyond Pesticides, June 24, 2025) As changes in the executive branch of the federal government upend expectations among environmental stakeholders, the regulation of food safety in the United States is being revealed as a rickety structure built over a century with unpredictable and sometimes contradictory additions, extensions, remodels, and tear-downs. In the short term, clarity is unavailable, but there have been calls for revision and strengthening of regulatory processes—requiring lawmaker and regulator willingness to incorporate the vast body of evidence that pesticides do far more harm than good, and that organic regenerative agriculture is the surest path to human and ecological health. News reports out of Costa Rica in May brought public attention to drafted legislation to ban pesticides in the country that the World Health Organization (WHO) has defined as “extremely or highly hazardous, or those with evidence of causing cancer, genetic mutations, or affecting reproduction, according to the Globally Harmonized System (GHS).” The headline sparked a relook in this Daily News at the current and historical failure of U.S. policy, which allows cancer-causing pesticides in food production and land management, despite the booming success of a cost-effective and productive, certified organic sector for which petrochemical pesticides are not […]
Posted in Agriculture, Alternatives/Organics, and Rodenticide Act (FIFRA), Breast Cancer, Cancer, Endocrine Disruption, Environmental Protection Agency (EPA), Immunotoxicity, multi-generational effects, non-Hodgkin's Lymphoma, Pesticide Mixtures, Pesticide Regulation, synergistic effects, Uncategorized, World Health Organization | No Comments »