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Daily News Blog

Archive for the 'metabolic syndrome' Category


27
Sep

Metabolic Diseases, Including Diabetes and Obesity, Driven by Pesticide Exposure

(Beyond Pesticides, September 27, 2023) A study published in Pesticide Biochemistry and Physiology finds organophosphate (OP), organochlorine (OC), and pyrethroid (PYR) pesticides have links to insulin resistance (IR) associated with metabolic disorders like diabetes, obesity, chronic kidney disease (CKD), and hypertension. Metabolic disorders are among the leading causes of morbidity and mortality, with over 11 percent (>37 million) of individuals in the U.S. having diabetes, and cases are growing by millions annually. Additionally, there is a rise in metabolic disorders among young people. Studies even find low levels of pesticide exposure during pregnancy or childhood cause adverse health effects, including metabolic disorders tied to gut microbiome disruption (dysbiosis). With increasing rates of diabetes and obesity, the two most prominent metabolic diseases in the study, cases among the global population, studies like these highlight the importance of evaluating how chemical contaminants deregulate normal bodily function through metabolic changes.  To investigate the association between pesticide exposure and insulin-related metabolic disorders in humans, researchers searched the PubMed database for articles, performing a systematic review. The study notes, “IR is defined as a pathological state in which a higher-than-normal level of insulin is required to produce the optimal response in cells.” The search generated 4,051 articles related to the topic. However, after excluding duplicates and […]

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07
Mar

Glyphosate Exposure Associated with Liver and Metabolic Disorders in Children, Young Adults

(Beyond Pesticides, March 7, 2023) Exposure to glyphosate (Roundup) and its breakdown products is associated with an increased risk of liver and metabolic disorders in children and young adults, according to research published in Environmental Health Perspectives earlier this month. While glyphosate has developed a well-deserved reputation as a carcinogen, research is finding that cancer is one of a myriad of chronic diseases associated with the notorious chemical. As this body of literature grows, growing awareness by the public is increasing pressure on the U.S. Environmental Protection Agency to cancel its allowed uses. Researchers began their investigation concerned about the rise of liver disorders and metabolic syndrome among young people. This trend has been pronounced among populations of color. The worrying increase has led many to consider synthetic chemical exposure as a contributing factor, as lack of diet and exercise is unlikely to account for the entirety of the increase. To better understand these impacts, researchers enrolled existing participants in the CHAMACOS (Center for the Health Assessment of Mothers and Children of Salinas) study, a long running cohort of mothers and their children born between the years 2000 and 2002 in the Salinas Valley of California. Enrolled participants consistent mostly […]

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