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Daily News Blog

Archive for the 'synergistic effects' Category


15
Oct

Take Action: EPA Must Evaluate the Effects of Multiple Pesticide Ingredient Use and Exposure

(Beyond Pesticides, October 15, 2019) EPA is requesting comment on its proposal to require data that will help it determine synergistic effects of some pesticides. EPA has received on a pressure on a number of fronts, including a report by the Center for Biological Diversity, a report by its own Inspector General, a letter from 35 Congressional Representatives, and research pointing to the unavoidability of synergistic effects—the chemical combinations that cause greater effects when mixed together than the sum of the individual chemical effects. Despite all of the evidence that synergism is the rule rather than the exception, EPA’s consideration focuses on a narrow range of cases in which pesticide product patents make claims of synergy. Tell EPA to always investigate synergy and to determine need for pesticides. One such product is Dow’s Enlist Duo, which combines glyphosate and 2,4-D in an attempt to overcome weed resistance. The focus on products and tank mixes where synergism is a selling point brings to light the fact that as a rule, EPA does not request efficacy data in registering pesticides not intended to protect public health. Thus, although required by law to weigh pesticide risks and benefits, EPA rarely has data to make […]

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29
Jul

EPA’s Office of Inspector General Must Investigate EPA’s Failure to Fully Assess Pesticide Hazards

(Beyond Pesticides, July 29, 2019) A research study, published in March in Scientific Reports, uncovers a pesticide effect on a sugar-metabolizing enzyme common to all cells that has broad health ramifications ignored by the U.S. Environmental Protection Agency’s (EPA) safety testing protocol. This finding raises a larger question regarding the need for EPA to test for the synergistic effects of pesticides, whereby pesticides and chemicals in combination have an even greater effect than they do by themselves. The research, by T. Tristan Brandhorst, PhD, Iain Kean, PhD, and others in the lab of Bruce Klein, PhD, of the University of Wisconsin–Madison and UW School ofMedicine and Public Health, specifically sheds light on the mode of action of the fungicide fludioxonil. Fludioxonil, a phenylpyrrole fungicide, was developed to treat seeds during storage, and has come to be used commonly on grains, vegetables, fruits, and ornamental plants during cultivation, and produce after harvest to extend “shelf life.” As reported by the American Association for the Advancement of Science publication, EurekAlert, “The ability of [the fungicide] fludioxonil to act on a sugar-metabolizing enzyme common to all cells, and to produce the damaging compound methylglyoxal, may mean that the pesticide has more potential to harm non-fungal cells than previously […]

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