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Daily News Blog

Archive for the 'Endocrine Disruption' Category


27
Sep

Neonicotinoid Insecticide Exposure Harms Amphibians Across Multiple Life Stages

(Beyond Pesticides, September 27, 2022) Exposure to widely used neonicotinoid insecticides harms amphibians at multiple life stages, adversely affecting their ability to survive in the wild, according to research published in the Journal of Zoology. As long-lived, systemic insecticides, neonicotinoids are consistently found in U.S. waterways,  often above federal safety limits, making these findings particularly dangerous for frogs and other amphibians throughout the country. As troubling data piles up on this class of dangerous insecticides, which are damaging pollinators, birds, deer, aquatic wildlife, and human health, it is left to the public to place pressure on federal regulators and members of Congress to act. To understand the impact of neonicotinoids on amphibian life stages, researchers conducted a range of  experiments. These were designed to investigate how exposure to the neonicotinoid imidacloprid affected larval survival, sexual development, locomotor skills, and avoidance behavior of the wood frog (Rana sylvatica). Larval survival was examined by exposing tadpoles to 10 parts per billion (ppb) of imidacloprid, a rate lower than the lethal concentration expected to kill half of other frogs species in acute toxicity tests. Four treatment protocols were established, adding the variable of natural pond drying to half of the tested frogs to […]

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15
Sep

With Global Disease Rates Rising, Do Pesticides Take Some of the Blame? Science Says, “Yes.”

(Beyond Pesticides, September 15, 2022) A review published in Scientific African finds pesticide exposure contributes to the increase in non-communicable diseases (NCDs) in Tanzania, reflecting implications for global health. There are four main NCDs, including cardiovascular diseases, cancers, respiratory diseases, and endocrine-disrupting diseases like diabetes. These diseases have no bacterial, viral, or fungal causes, but are chronic diseases with risk factors like genetics, tobacco/alcohol use, physical activity, and diet, thus lacking transmission between people. However, research is now investigating the role environmental factors play in NCD risks, such as outdoor and indoor air pollution, exposure to chemicals, radiation, and occupation. Regardless of whether working together or separately, these risk factors contribute to NCDs and subsequent health conditions. Non-communicable diseases are on the rise, and the World Health Organization (WHO) classifies non-communicable diseases as the number one cause of death globally, affecting 41 million individuals. Moreover, WHO estimates NCD death rates to increase by 17 percent in the next decade, significantly surpassing deaths from communicable, maternal, perinatal, and nutritional diseases combined. Therefore, the report notes, “This review is informative to the policy, practices, and intervention towards the existing situation of pesticides in Tanzania. In addition, it calls for further investigation of the absence of data […]

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12
Aug

Endocrine Disrupting Chemicals Contribute to Liver Injury, including Toxic PFAS and Pesticides

(Beyond Pesticides, August 12, 2022) Gestational (during pregnancy) exposure to endocrine disrupting chemicals (EDCs) like pesticides, per- and polyfluoroalkyl substances (PFAS), among others, may increase pediatric (child) liver injury and non-alcoholic fatty liver disease (NAFLD) risk, according to a study published in Environmental Health. Past studies associate exposure to EDCs with increased susceptibility to adverse health effects during critical fetal and childhood developmental periods. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Endocrine disruption can lead to several health problems, including hormone-related cancer development (i.e., thyroid, breast, ovarian, prostate, testicular), reproductive dysfunction, and diabetes/obesity that can span generations. Because EDCs are ubiquitous because they are found in many products, studies report that these toxic chemical compounds are detectable in infants, children, and pregnant women. Furthermore, pregnant women can readily transfer compounds to the developing fetus through the placenta. Therefore, it is essential to understand the mechanism behind how harmful chemical exposure induces endocrine disruption during critical developmental periods. Researchers note, “Considering the lack of studies on endocrine disruption and pediatric NAFLD, research like this highlights the need to understand the underlying […]

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09
Aug

“Inert” Pesticide Ingredients and Failure to Regulate Raise Dangers for All U.S. Residents

(Beyond Pesticides, August 9, 2022) The most widely used pesticide chemicals in the United States are not listed on product labels, yet pose widespread environmental and public health hazards, according to commentary published this month in Environmental Health Perspectives by two veteran researchers. At issue are adjuvants and so-called “inert” (or “other”) ingredients, chemicals that are added to formulated pesticide products, but do not undergo the same safety reviews as the active ingredient in pesticide products. This donut hole of regulation has permitted, as the commentary shows, millions of pounds of chemicals to be applied in California and throughout the country without proper scientific evaluation of their human health or ecological impact. Researchers first draw a distinction between adjuvant products and inert ingredients in pesticide products. Adjuvants are materials specifically designed to improve the performance of a pesticide spray and are sold separately from formulated pesticide products. Adjuvants are “tank mixed” with a pesticide prior its application. Inert ingredients are any ingredient within a formulated pesticide product that is not designed to prevent, destroy, or repel a pest. Adjuvants and inert ingredients can be the same material – the difference lies in when they are added to a formulated pesticide […]

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21
Jul

Pesticide Exposure Driving Liver Disease through Hormone Disrupting Mechanisms

(Beyond Pesticides, July 21, 2022) Research published in Scientific Reports finds an association between the increasing emergence of nonalcoholic fatty liver disease (NAFLD) and exposure to endocrine (hormone) disrupting chemicals, like organochlorine pesticides (OCPs). It is well-known that traces of legacy (past-use) pesticides, like organochlorines, remain in the environment for decades—possibly centuries, post-final application, as OCPs have greater chemical stability and gradual attenuation. However, these chemicals have profound adverse impacts on human health, especially on the endocrine system. Obesity, insulin resistance, type 2 diabetes, and elevated liver enzyme resulting from endocrine disruption contribute to NAFLD and can lead to liver cirrhosis. Although some, but not all, manufacturing and use of specific OCPs have declined in the U.S., OCPs remain a global issue, as much of the developing world still reports usage. Considering the lack of studies on OCP-induced endocrine disruption and NAFLD, research like this highlights the need to understand the underlying mechanisms that contribute to growing endocrine disease incidents.   The study determined that there is an association between OCP exposure and NAFLD using the fatty liver index (FLI), a predictor of lipid (fat) accumulation in the liver. The researcher collected blood serum to measure the concentration of OCPs, specifically evaluating detectable […]

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18
Jul

Take Action: Male Fertility Harmed by Pesticides and EPA Dysfunction

(Beyond Pesticides, July 18, 2022) The failure of the U.S. Environmental Protection Agency (EPA) to meet its statutory responsibility to protect people and wildlife from the dire consequences of exposure to endocrine disrupting chemicals must end. A study published in Toxicology and Applied Pharmacology adds urgency to the need to eliminate endocrine-disrupting pesticides. The authors find that prepubescent exposure to endocrine-disrupting chemicals (EDCs), including pesticides, impairs male reproduction through the interruption of testicular homeostasis and development of reproductive Leydig cells, and can have multigenerational effects. This adds to the long list of scientific articles showing EPA neglect of the devastating effects of widely used pesticides. Tell EPA that pesticide use cannot continue without findings of no endocrine disruption. Tell Congress to ensure that EPA does its job. More than 50 pesticide active ingredients have been identified as endocrine disruptors that mimic the action of a naturally-produced hormone, such as estrogen or testosterone, thereby setting off similar chemical reactions in the body; block hormone receptors in cells, thereby preventing the action of normal hormones; or affect the synthesis, transport, metabolism and excretion of hormones, thus altering the concentrations of natural hormones. Endocrine disruptors have been linked to attention deficit hyperactivity disorder (ADHD), […]

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14
Jul

Endocrine-Disrupting Chemicals Impair Juvenile Male Fertility Development and Threatens Future Reproductive Health

(Beyond Pesticides, July 14, 2022) A study published in Toxicology and Applied Pharmacology finds prepubescent exposure to endocrine-disrupting chemicals (EDCs), including pesticides, impairs male reproduction through the interruption of testicular homeostasis and development of reproductive Leydig cells. Endocrine disruptors are xenobiotic (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem). Many reports demonstrate that exposure to endocrine-disrupting chemicals can adversely affect human, animal—and thus environmental—health by altering the natural hormones in the body responsible for conventional reproductive, physical, and mental development. Scientists and health officials already associate pesticide exposure with a decrease in male fertility, including reduced sperm count, quality, and abnormal sperm development. The presence of pesticides in the body has implications for human health, especially during vulnerable life stages, such as childhood, puberty, pregnancy, and old age. Therefore, it is essential to understand how exposure to toxic chemicals in the environment affects future reproductive success and health. The researchers note, “Recent studies revealed that exposures to EDCs during so-called critical windows of susceptibility (prenatal, prepubertal, pubertal, and aging periods) could disrupt healthy patterns of testes development and homeostasis, which can be demonstrated as an impaired testicular function later in life. However, much more work is needed to understand better the cellular […]

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16
Jun

Farmed Salmon Just as Toxic to Human Health as Junk Food

(Beyond Pesticides, June 16, 2022) Farmed salmon serves as an inferior food source, accumulating more toxic chemicals in fatty tissue with fewer healthy nutrient properties based on a study from the University of Bergen, Norway and Alternative Medicine Review. However, the issue of toxic chemical contamination in fish dates back decades with investigations demonstrating high levels of persistent organic pollutants (POPs), including polybrominated diphenyl ethers (PBDEs) flame retardants restricted or banned in the U.S. and U.K., polychlorinated biphenyl (PCBs), dioxin (a by-product of pesticide manufacturing), and ethoxyquin (a pesticide preservative in fish feed). The aquaculture industry (e.g., farmed seafood/fish) repeatedly faces sustainability issues, failing to adhere to environmental regulations and threatening marine health. Extensive use of pesticides in local marine ecosystems has induced coastal habitat loss and increased genetic and health risks to wild marine populations. Moreover, insecticides used to kill salmon parasites (e.g., fish lice) has led to widespread disease persistence and pest resistance. Marine species biodiversity is rapidly declining due to overfishing, global warming, pathogens, and pollution. Thus, further biodiversity loss can change aquatic and terrestrial ecosystem functions and reduce ecosystem services. Food analysis results find the consumption of farmed salmon fillets contributes to higher rates of metabolic disorders, including diabetes and obesity. These farmed salmon also contain levels […]

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15
Apr

Beyond Pesticides Makes Science-based Case that It Is Imperative to Phase Out Pesticides in a Decade

The organic solutions to problems highlighted in the latest issue of Pesticides and You—based on the importance of healthy ecosystems and public health protection—are within reach, and the data creates an imperative for action now that phases out pesticides within a decade, while ensuring food productivity, resilient land management, and safe food, air, and water. (Beyond Pesticides, April 15, 2022) The current issue of Pesticides and You, RETROSPECTIVE 2021: A Call to Urgent Action, is a look at a year of science, policy, and advocacy that informs both the existential problems that the U.S. and the world are facing due to toxic pesticide dependency, and solutions that can be adopted now. The information in this issue captures the body of science that empowers action at the local, state, and federal level, and provides a framework for challenging toxic pesticide use and putting alternatives in place. The issue finds that 2021 was a pivotal year in both defining the problem and advancing the solution. This year in review is divided into nine sections that provide an accounting of scientific findings documenting serious pesticide-induced health and environmental effects, disproportionate risk to people of color and those with preexisting conditions, regulatory failures, at the same time […]

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03
Dec

Degenerative Lung Diseases Associated with Atrazine Exposure, Worsened in Combination with Common Cancer Treatment

(Beyond Pesticides, December 2, 2021) A study published in Cellular Physiology and Biochemistry finds atrazine (ATR) exposure worsens lung disease outcomes in individuals with idiopathic (spontaneous) pulmonary fibrosis (IPF), a group of incurable lung diseases involving damaged/scarred lung tissue. Furthermore, chemotherapeutic products used to treat lymphoma (immune system cell cancer) like bleomycin can induce pulmonary fibrosis complications exacerbated by pesticide exposure. However, pesticide-related pulmonary fibrosis can have implications for neurological health, such as motor function. Scientific literature already finds an association between pesticide exposure and respiratory illnesses such as asthma, lung cancer, and chronic obstructive pulmonary disease (chronic bronchitis). Although IPF impacts over 5 million people a year globally, the disease is difficult to predict, which is concerning as the death rate is 50 to 56 percent within the first few years. Therefore, studies like this highlight the significance of evaluating how pesticide exposure impacts respiratory function, especially when exposure to respiratory toxicants increases vulnerability to existing respiratory-fixated illnesses like Covid-19. Advocate have urged the U.S. Environmental Protection (EPA) to incorporate scientific findings that these—where chemical exposures exacerbate an existing medical condition—into its pesticide registration review program. Researchers note, “[O]ur data represent an addition to the complex information on ATR-induced pulmonary toxicity. In particular, in this […]

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01
Dec

Banned Pesticides Associated with Endometriosis

(Beyond Pesticides, December 1, 2021) Women exposed to metabolites of the banned insecticide chlordane are over three times more likely to develop endometriosis, finds research published in the journal Environment International. The study is the latest to find links between persistent organic pollutants (POPs), still lingering in our environment and in our bodies, and chronic disease. According to an economic analysis conducted in 2016, exposure to endocrine (hormone) disrupting chemicals, often implicated in considerable damage to the body’s reproductive system, results in billions of dollars of health care costs from female reproductive disorders. Researchers set out to integrate two methodologies into their evaluation, combining analysis of POP biomarkers in blood with an analysis of biomarkers in that body that correspond with cell functioning, inflammation, and stress. A total of 87 women were enrolled in the study, half of whom had deep endometriosis, a quarter of whom also had the disease and sought surgical intervention, and a remaining quarter without reproductive concerns acted as a control. Twenty polychlorinated biphenyls (PCBs) and 30 organochlorine pesticide compounds were analyzed, as were various biomarkers and inflammatory cytokines. The analysis revealed two compounds to be positively associated with endometriosis – trans-nonachlor, a breakdown product of […]

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10
Sep

More Scientific Evidence that Endocrine-Disrupting Pesticides Disrupt Thyroid Function

(Beyond Pesticides, September 10, 2021) Research conducted in Thailand shows that exposures to pesticides, even at low levels, can impact the human endocrine system and distort thyroid function. The study looked specifically at interactions of genetics and environment: it investigated associations between variations in genes involved in pesticide metabolism and altered thyroid hormone concentrations in agricultural workers. This research underscores some of the complexity and difficulty of determining human vulnerability to impacts of pesticide exposures, given genetic variables. Beyond Pesticides believes that this very complexity is a cogent argument for anchoring regulation of pesticides in the Precautionary Principle. If exposure to a pesticide can cause damage to human (or environmental) health, it sometimes will do so. Thus, to protect people’s health, agriculture and other land management practices must transition from the use of synthetic pesticides to broad adoption of organic regenerative approaches that obviate the need for such chemicals. This research is part of a longitudinal study that seeks to evaluate sub-chronic impacts, on thyroid hormone levels, of repeated exposures to a variety of pesticides. The farmworkers studied in this phase comprise two groups: those working on organically managed farms (216 subjects), and those working on conventional farms that use pesticides […]

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09
Sep

Endocrine (Hormone) Disrupting Chemicals, Including Pesticides, Also Affect the Nervous System

(Beyond Pesticides, September 9, 2021) A new study published in Toxicology Reports finds the same chemicals that disrupt the endocrine (hormone) system also disrupt the nervous system. Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem) present in nearly all organisms and ecosystems. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Past research shows exposure to endocrine-disrupting pesticides adversely affects human health, from reproductive function to cancer development, and effects can span generations. However, this study is one of the few to evaluate associations between endocrine-disrupting chemicals and neurological function. Although the etiology (cause) of many sporadic (non-heritable) neurological diseases are unknown, scientists suggest exposure to environmental toxicants plays a role in disease development. Therefore, government and health officials have been urged to consider how exposure to endocrine-disrupting chemicals can impact bodily function and development apart from hormone disruption.   In the body, cells communicate through electrical or chemical signals transmitted within the nervous or endocrine system. Studies find exposure to endocrine-disrupting chemicals has a direct and indirect impact on hormone function and development. However, researchers investigated whether […]

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30
Aug

Tell EPA to Ban ALL Uses of Chlorpyrifos

(Beyond Pesticides, August 30, 2021) As with other actions on pesticides, EPA’s chlorpyrifos decision is filled with exceptions that respond to vested interests seeking to ignore or deflect the science. EPA, since announcing its decision in 1999 to ban “residential” uses of chlorpyrifos, continues to allow the following uses: (i) Residential use of containerized baits; (ii) Indoor areas where children will not be exposed, including only ship holds, railroad boxcars, industrial plants, manufacturing plants, or food processing plants; (iii) Outdoor areas where children will not be exposed, including only: golf courses, road medians, Industrial plant sites; (iv) Non-structural wood treatments including: fenceposts, utility poles, railroad ties, landscape timers, logs, pallets, wooden containers, poles, posts, and processed wood products; (v) Public health uses: Fire ant mounds (drench and granular treatment); (vi) nurseries and greenhouses; and (vii) Mosquito control. These uses are unaffected by EPA’s announcement. We need to finish the chlorpyrifos job. Tell EPA to ban all uses of chlorpyrifos. The collective effort to remove this one chemical is a tremendous feat in eliminating one exposure to a hazardous material for children. Achieving the ban on food uses required an enormously resource-intensive effort at a time in history when we are […]

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16
Aug

Tell EPA: It Must Ban Pesticides Unless Shown Not To Be Endocrine Disruptors

(Beyond Pesticides, August 16, 2021) The failure of the U.S. Environmental Protection Agency (EPA) to meet its statutory responsibility to protect people and wildlife from the dire consequences of exposure to endocrine-disrupting chemicals must end. The Office of the Inspector General (OIG) for EPA has issued a damning report on the agency’s progress in protecting the population from potentially damaging endocrine disruption impacts of exposures to synthetic chemical pesticides (and other chemicals of concern) that shows the situation to be even worse than previously reported. The OIG’s summary statement says, “Without the required testing and an effective system of internal controls, the EPA cannot make measurable progress toward complying with statutory requirements or safeguarding human health and the environment against risks from endocrine-disrupting chemicals.” As a result, according to the OIG, “we have yet to see EPA use endocrine disruption findings in pesticide registration decisions.” Tell EPA that pesticide use cannot continue without findings of no endocrine disruption. Over recent decades, evidence has mounted showing that many pesticides interfere with hormones—and are therefore endocrine-disrupting chemicals (EDCs). In 1996, the promise of screening pesticides for endocrine disruption generated support from environmentalists and public health advocates for the Food Quality Protection Act […]

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29
Jun

Maine Aerial Forestry Spray Ban of Glyphosate and Other Herbicides Vetoed by Governor, Override Effort Begins

(Beyond Pesticides, June 29, 2021) Maine Governor Janet Mills (D) last week vetoed legislation prohibiting the aerial use of glyphosate and other dangerous herbicides in forestry practices. LD125, An Act To Prohibit the Aerial Spraying of Glyphosate and Other Synthetic Herbicides for the Purpose of Silviculture, was supported by a wide range of health and conservation groups, and aimed to bring the state in line with best practices for public health and the environment. With Maine recently passing one of the strongest consumer bans on pollinator-toxic neonicotinoids, advocates are dismayed by the setback from the Governor’s office. In a statement to Maine Public Radio, Senate President Troy Jackson said that Governor Mills should stop referring to herself as an environmentalist. “The science across the country, across the world, says that this stuff kills people, kills wildlife,” Mr. Jackson says. “And all that it is, is a giveaway to the large landowners so they can maximize their profits off the lives of the people in Maine and the wildlife in Maine.” Senator Jackson’s words are stern yet factual. Glyphosate has been identified by the World Health Organization as a probable human carcinogen. Monsanto, now owned by Bayer, has been the subject […]

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28
Jun

Take Action: Tell EPA to Ban ALL Triazine Herbicides

(Beyond Pesticides, June 28, 2021) The endocrine disrupting herbicide propazine (in the triazine family of frog-deforming endocrine disruptors) is set for cancellation by the U.S. Environmental Protection Agency (EPA). The move would eliminate use of the hazardous herbicide by the end of 2022. However, all pesticides in the triazine class, including atrazine and simazine, have similar properties and should be eliminated from use. Tell EPA to finish the job by banning all triazines. In November 2020, Beyond Pesticides and allied environmental groups launched a lawsuit against EPA for its intent to reregister the triazine family of chemicals. The agency’s interim approval of the herbicides, conducted under the Trump administration, eliminates important safeguards for children’s health and a monitoring programs intended to protect groundwater from contamination. As is typical with EPA, the agency merely proposed minor label changes in attempts to mitigate risks identified in its registration review. According to a release from EPA, it made the decision not out of concerns relating to human health and environmental protection, but in order to provide “regulatory certainty” for farmers and local officials. In March 2021, the Biden administration requested a stay on the atrazine lawsuit brought by environmental groups, as it indicated […]

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15
Jun

Propazine Cancelled by EPA—Advocates Urge Agency to Finish the Job by Banning Atrazine and Simazine

(Beyond Pesticides, June 15, 2021) The endocrine disrupting herbicide propazine (in the triazine family of frog-deforming endocrine disruptors) is set for cancellation by the U.S. Environmental Protection Agency (EPA), according to a Federal Register notice published last week. The move would eliminate use of the hazardous herbicide by the end of 2022. While health and environmental advocates are pleased with the agency’s move, they say it is critical that all pesticides in the triazine class, including atrazine and simazine, also be eliminated from use. In November 2020, Beyond Pesticides and allied environmental groups launched a lawsuit against EPA for its intent to reregister the triazine family of chemicals. The agency’s interim approval of the herbicides, conducted under the Trump administration, eliminates important safeguards for children’s health and a monitoring programs intended to protect groundwater from contamination. As is typical with EPA, the agency merely proposed minor label changes in attempts to avert risks identified in its registration review. According to a release from EPA, it made the decision not out of concerns relating to human health and environmental protection, but in order to provide “regulatory certainty” for farmers and local officials. In March 2021, the Biden administration requested a stay […]

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14
Jun

Cutting Edge Science Must be Considered…See Science and Policy at the National Pesticide Forum 

(Beyond Pesticides, June 14, 2021) Beyond Pesticides reports regularly on new science showing how pesticides harm human health and ecosystems. This science is not factored into EPA decisions. Tell EPA that cutting-edge science must be considered. More than 50 pesticide active ingredients have been identified as endocrine disruptors that mimic the action of a naturally-produced hormone, such as estrogen or testosterone, thereby setting off similar chemical reactions in the body; block hormone receptors in cells, thereby preventing the action of normal hormones; or affect the synthesis, transport, metabolism and excretion of hormones, thus altering the concentrations of natural hormones. Endocrine disruptors have been linked to attention deficit hyperactivity disorder (ADHD), Parkinson’s and Alzheimer’s diseases, diabetes, cardiovascular disease, obesity, early puberty, infertility and other reproductive disorders, childhood and adult cancers, and other metabolic disorders. Similar effects are found in other species. In spite of legal requirements and the flood of research, EPA issues Proposed Interim Decisions (PIDs) on pesticide registrations making no human health or environmental safety findings associated with the potential for endocrine disruption, or identifying additional data needs to satisfy Endocrine Disruptor Screening Program requirements in the PIDs. EPA cannot make findings of no unreasonable adverse effects without findings […]

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06
May

Breakdown Products (Metabolites) from Pesticides May Be More Toxic than Parent Compound, Study Finds

(Beyond Pesticides, May 6, 2021) Nearly half of all breakdown products (transformation products) from four common-use environmental pesticides produce stronger endocrine (hormone) disrupting (ED) effects than the parent compound, according to new research published in Environment International. Over 300 environmental contaminants and their byproducts—from chemicals in plastics to cosmetic/personal care products—are commonly present in water bodies, food commodities, and human blood/urine samples. These toxicants can alter hormone metabolism, producing endocrine-disrupting effects that put the health of animals, humans, and the environment at risk. Many ecological and health risk assessments for pesticides focus on the effects of parent chemical compound products, overlooking the potential impacts of transformation products (TPs). Therefore, studies like these highlight the need to assess the implications of TPs to safeguard human, animal, and environmental health. The researchers note, “Since an increasing number of pesticide TPs have been detected in various environmental media, a more comprehensive understanding of the ecological risk of pesticide TPs is imperative for risk assessments more extensively and regulatory policy-making on pesticide restriction in the future.” Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem), including pesticides, bisphenols, phthalates, persistent organic pollutants (POPs), and heavy metals. Past research demonstrates exposure […]

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05
Apr

Ban Endocrine Disrupting Pesticides Now

(Beyond Pesticides, April 5, 2021) The failure of EPA to meet its statutory responsibility to protect people and wildlife from the dire consequences of exposure to endocrine disrupting chemicals must end. Over recent decades, evidence has mounted showing that many pesticides interfere with hormones—and are therefore endocrine-disrupting chemicals (EDCs). In 1996, the promise of screening pesticides for endocrine disruption generated support from environmentalists and public health advocates for the Food Quality Protection Act (FQPA), which traded the absolute prohibition of carcinogens in food of the Delaney Clause for a risk assessment standard that is subject to manipulation and an underestimation of real-life hazards. And now, 25 years later, we have yet to see EPA use endocrine disruption findings in pesticide registration decisions. >>Tell EPA that pesticide use cannot continue without findings of no endocrine disruption. The endocrine system consists of a set of glands (thyroid, gonads, adrenal and pituitary) and the hormones they produce (thyroxine, estrogen, testosterone and adrenaline), which help guide the development, growth, reproduction, and behavior of animals, including humans. Hormones are signaling molecules, which travel through the bloodstream and elicit responses in other parts of the body. More than 50 pesticide active ingredients have been identified as […]

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18
Mar

Common Use Organophosphate Insecticides Pose a Greater Threat to Women’s Health

(Beyond Pesticides, March 18, 2021) A new study published in Environmental Toxicology and Pharmacology finds chronic (long-term) organophosphate (OP) pesticide exposure increases adverse health and cancer risk for U.S. women relative to men. Organophosphorus pesticides have a wide range of biological uses—from insecticides to flame retardants—that make these chemicals ubiquitous, significantly contributing to ecosystem contamination. Furthermore, while organophosphates have less bioaccumulation potential, residues are consistently present in human and animal blood, urine, tissues, and milk. Although research demonstrates that OPs are highly toxic, there remains an inadequate understanding of how OP exposure impacts the nonagricultural population in the U.S., especially women. Therefore, it is essential to investigate the sex-specific health effects chemical contaminants can produce to mitigate exposure among vulnerable populations. Study researchers note, “Given the higher burden of OP exposure and their significantly higher overall health risk, including cancer, reducing OP exposure in U.S. women needs to be prioritized.” To examine the relationship between OP exposure and health risks, researchers investigated the presence of commonly detected OP metabolite concentrations in urine using participants from the U.S. National Health and Nutrition Examination Survey (NHANES). Urine samples measure OP metabolite as an indicator of OP exposure like previous agriculture-related population surveys. Study participants report health issues […]

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09
Mar

EPA Proposes Cancellation of Highly Toxic Wood Preservative Pentachlorophenol (“Penta”)

(Beyond Pesticides, March 9, 2021) Last week, the Environmental Protection Agency (EPA) announced an interim decision to cancel of one of the most hazardous pesticides still used in the United States, pentachlorophenol (penta). Although long overdue, health advocates are hailing the agency’s action, taken due to significant risks to human health, the availability of alternatives, and the uncertain future of penta production. Many advocates hope that EPA’s announcement is the start of a pivot to science-based decision-making in the best interest of health and the environment, not the pockets of pesticide industry executives. Cancellation of this toxic chemical will bring  the U.S. into conformance with the Stockholm Convention, an international treaty to ban persistent organic pollutants (POPs) joined by over 150 countries that was never ratified by the U.S. “This has been a long time coming,” said Jay Feldman, executive director of Beyond Pesticides. “After decades of scientific reports, lawsuits, regulatory comments, and an international ban, we’re glad EPA finally acknowledged the intrinsic dangers posed by continuing penta’s registration. We urge the agency expedite its slow cancellation timeline so that we can finally eliminate this unnecessary pollutant.” Produced for its ability to preserve wood through pressure treatment, penta has been […]

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