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Daily News Blog

Archive for the 'Endocrine Disruption' Category


06
May

Breakdown Products (Metabolites) from Pesticides May Be More Toxic than Parent Compound, Study Finds

(Beyond Pesticides, May 6, 2021) Nearly half of all breakdown products (transformation products) from four common-use environmental pesticides produce stronger endocrine (hormone) disrupting (ED) effects than the parent compound, according to new research published in Environment International. Over 300 environmental contaminants and their byproducts—from chemicals in plastics to cosmetic/personal care products—are commonly present in water bodies, food commodities, and human blood/urine samples. These toxicants can alter hormone metabolism, producing endocrine-disrupting effects that put the health of animals, humans, and the environment at risk. Many ecological and health risk assessments for pesticides focus on the effects of parent chemical compound products, overlooking the potential impacts of transformation products (TPs). Therefore, studies like these highlight the need to assess the implications of TPs to safeguard human, animal, and environmental health. The researchers note, “Since an increasing number of pesticide TPs have been detected in various environmental media, a more comprehensive understanding of the ecological risk of pesticide TPs is imperative for risk assessments more extensively and regulatory policy-making on pesticide restriction in the future.” Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem), including pesticides, bisphenols, phthalates, persistent organic pollutants (POPs), and heavy metals. Past research demonstrates exposure […]

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05
Apr

Ban Endocrine Disrupting Pesticides Now

(Beyond Pesticides, April 5, 2021) The failure of EPA to meet its statutory responsibility to protect people and wildlife from the dire consequences of exposure to endocrine disrupting chemicals must end. Over recent decades, evidence has mounted showing that many pesticides interfere with hormones—and are therefore endocrine-disrupting chemicals (EDCs). In 1996, the promise of screening pesticides for endocrine disruption generated support from environmentalists and public health advocates for the Food Quality Protection Act (FQPA), which traded the absolute prohibition of carcinogens in food of the Delaney Clause for a risk assessment standard that is subject to manipulation and an underestimation of real-life hazards. And now, 25 years later, we have yet to see EPA use endocrine disruption findings in pesticide registration decisions. >>Tell EPA that pesticide use cannot continue without findings of no endocrine disruption. The endocrine system consists of a set of glands (thyroid, gonads, adrenal and pituitary) and the hormones they produce (thyroxine, estrogen, testosterone and adrenaline), which help guide the development, growth, reproduction, and behavior of animals, including humans. Hormones are signaling molecules, which travel through the bloodstream and elicit responses in other parts of the body. More than 50 pesticide active ingredients have been identified as […]

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18
Mar

Common Use Organophosphate Insecticides Pose a Greater Threat to Women’s Health

(Beyond Pesticides, March 18, 2021) A new study published in Environmental Toxicology and Pharmacology finds chronic (long-term) organophosphate (OP) pesticide exposure increases adverse health and cancer risk for U.S. women relative to men. Organophosphorus pesticides have a wide range of biological uses—from insecticides to flame retardants—that make these chemicals ubiquitous, significantly contributing to ecosystem contamination. Furthermore, while organophosphates have less bioaccumulation potential, residues are consistently present in human and animal blood, urine, tissues, and milk. Although research demonstrates that OPs are highly toxic, there remains an inadequate understanding of how OP exposure impacts the nonagricultural population in the U.S., especially women. Therefore, it is essential to investigate the sex-specific health effects chemical contaminants can produce to mitigate exposure among vulnerable populations. Study researchers note, “Given the higher burden of OP exposure and their significantly higher overall health risk, including cancer, reducing OP exposure in U.S. women needs to be prioritized.” To examine the relationship between OP exposure and health risks, researchers investigated the presence of commonly detected OP metabolite concentrations in urine using participants from the U.S. National Health and Nutrition Examination Survey (NHANES). Urine samples measure OP metabolite as an indicator of OP exposure like previous agriculture-related population surveys. Study participants report health issues […]

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09
Mar

EPA Proposes Cancellation of Highly Toxic Wood Preservative Pentachlorophenol (“Penta”)

(Beyond Pesticides, March 9, 2021) Last week, the Environmental Protection Agency (EPA) announced an interim decision to cancel of one of the most hazardous pesticides still used in the United States, pentachlorophenol (penta). Although long overdue, health advocates are hailing the agency’s action, taken due to significant risks to human health, the availability of alternatives, and the uncertain future of penta production. Many advocates hope that EPA’s announcement is the start of a pivot to science-based decision-making in the best interest of health and the environment, not the pockets of pesticide industry executives. Cancellation of this toxic chemical will bring  the U.S. into conformance with the Stockholm Convention, an international treaty to ban persistent organic pollutants (POPs) joined by over 150 countries that was never ratified by the U.S. “This has been a long time coming,” said Jay Feldman, executive director of Beyond Pesticides. “After decades of scientific reports, lawsuits, regulatory comments, and an international ban, we’re glad EPA finally acknowledged the intrinsic dangers posed by continuing penta’s registration. We urge the agency expedite its slow cancellation timeline so that we can finally eliminate this unnecessary pollutant.” Produced for its ability to preserve wood through pressure treatment, penta has been […]

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11
Feb

New Mexico Bill Will Protect Children from Toxic Pesticides Where They Learn and Play

(Santa Fe, New Mexico, February 11, 2021)—New Mexico State Senator Brenda McKenna  introduced the Public Schools Pesticide Management Act (PSPMA) (SB 326) in order to protect school children from exposure to toxic pesticides where they learn and play. The legislation advances ecological pest management, an environmentally healthy way to protect children and the public from weeds and pests, within all schools, classrooms, community parks, and playgrounds in the state. Under PSPMA, only organic and minimum risk pesticides, the least toxic, yet still-effective products on the market will be allowed. Toxic pesticide use will be permitted only under a defined public health emergency, as determined by a public health official. The law does not address the use of pesticides in farming or agriculture.  “All children in New Mexico have the right to a safe environment where they learn and play,” said State Senator Brenda McKenna. “This legislation embraces an environmentally healthy approach to pest management, so families do not have to worry about the use of toxic pesticides in schools and communities.” Pesticide exposure presents unique dangers to children’s health. Children’s developing organ systems are less able to detoxify harmful chemicals, and they often come into closer contact with pesticides than adults in […]

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22
Jan

Will Biden Reverse Last Minute Trump EPA Approval of the Deadly Insecticide Aldicarb, Previously Cancelled?

(Beyond Pesticides, January 22, 2021) After the past four devastating years, hopes and expectations of the Biden/Harris administration abound among the environmental and public health communities. The ears and eyes of many advocates, as well as those in the agricultural community, are attuned (among myriad candidates) to the fate of the pesticide aldicarb. Although Environmental Protection Agency (EPA) registration of this terribly toxic insecticide was cancelled in 2010, various limited-use reapprovals since then have meant that the compound has found its way to increasing levels of use. On January 12, as another parting shot of midnight rulemaking, Trump’s EPA approved expanded uses (see below). The $64,000 question is whether the new administration will use its authority under the Congressional Review Act — which enables Congress to pass a joint resolution (then signed by the President) to overturn a new federal agency rule and prevent its reissuance in the future — to get this pesticide retired for good. Beyond Pesticides urges President Biden’s EPA to do so. Notably, the Trump administration used the Congressional Review Act to destroy myriad environmental rules when it came into power. This permitting of expanded aldicarb uses fits the pattern. Environmental Health News notes that, as of early […]

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14
Oct

Insecticide Linked to Testicular Cancer, With Latinos Disproportionately Affected

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22
Sep

EPA Reapproves Toxic Weedkiller Atrazine with Fewer Protections for Children’s Health

(Beyond Pesticides, September 22, 2020) Use of the highly hazardous, endocrine disrupting weed killer atrazine is likely to expand following a decision made earlier this month by the U.S. Environmental Protection Agency (EPA). Under the guise of “regulatory certainty,” the agency is reapproving use of this notorious herbicide, as well as its cousins simazine and propazine in the triazine family of chemicals, with fewer safeguards for public health, particularly young children. Advocates are incensed by the decision and vow to continue to put pressure on the agency. “Use of this extremely dangerous pesticide should be banned, not expanded,” Nathan Donley, PhD, a senior scientist at the Center for Biological Diversity said in a press release. “This disgusting decision directly endangers the health of millions of Americans.” Beyond Pesticides has long argued against the continued use of the triazine herbicides, which includes atrazine. Triazines are well known to interfere with the body’s endocrine, or hormonal system. Disruptions within this delicately balanced process in the body can result in a range of ill health effects, including cancer, reproductive dysfunction, and developmental harm. These weedkillers interfere with the pituitary gland’s release of luteinizing hormones, which regulate the function of female ovaries and male gonads. In comments written by Beyond Pesticides to EPA, the organization notes, “Of the numerous adverse effects associated with this disruption, […]

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21
Jul

Combined Effects of Pesticide Exposure and Climate Change Significantly Harm Coral Reef Fish

(Beyond Pesticides, July 21, 2020) Climate change and pesticide pollution are known to put coral reef fish at significant risk, but research published in Nature Communications shows how these risks can be both overlapping and synergistic. “Fish face a variety of human-induced stressors including increasing water temperatures and pollution from agricultural pesticides,” says study coauthor William Feeney, PhD from Griffith University. According to researchers, both of these stressors alone harm the endocrine (hormone) system and are subsequently exacerbated in combination with each other. To study the impact of climate change and pesticide pollution, researchers exposed convict surgeon fish (Acanthurus triostegus) to varying levels of water temperature increases, as well as varying levels of the insecticide chlorpyrifos. The scientists then observed how these changes affected the level of hormones the fish were expressing, and how they acted in the presence of predators. “Both a three-degree temperature increase and exposure to pesticide led to a decrease in the amount of thyroid hormones in exposed fish,” said Marc Besson, PhD, lead author, from PSL Research University, Paris. “These hormones control the development of sensory structures such as the retina, the nostrils and the lateral line, which enables fish to detect nearby water movement.” […]

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02
Jul

Endocrine Disrupting Chemicals, Including Pesticides, Have a Multi-Generational Impact on Commercially Beneficial Inland Silverside Fish

(Beyond Pesticides, July 2, 2020) Exposure to low levels of endocrine-disrupting chemicals commonly in waterways, including pesticides, can impact future generations of major commercial fish, despite no direct exposure to the chemicals, according to research published in the journal Frontiers in Marine Science by Oregon State University (OSU) researchers. Many studies assess the acute or chronic health implications associated with endocrine disruptors on a single generation but lack information on multi-generational impacts that can provide vital information on the fundamental survivability or fitness of many species. This study highlights the significance of understanding the implications of endocrine disruptors, even at low levels of exposure, as parental exposure can have adverse epigenetic consequences for future generations. Kaley Major, a Ph.D. fellow at Oregon State University (OSU) and lead research author, explains, “What t[his] gets at is something your grandparents may have come into contact within their environment can still be affecting the overall structure of your DNA in your life today.” Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem). Past research shows exposures to endocrine-disrupting chemicals can adversely impact human, animal—and thus environmental—health, by altering the natural hormones in the body responsible for […]

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30
Jun

Implications for Human Health: Pesticides and Other Environmental Contaminants Alter Gut Microbiome

(Beyond Pesticides, June 30, 2020) A review of scientific literature on the toxic effect of environmental contaminants—including pesticides—published in the journal Toxicological Science, “The Impact of Environmental Chemicals on the Gut Microbiome,” associates these chemicals to changes in the gut microbiome and other adverse health implications. The review, by researchers at the University of Illinois, looks at how environmental contaminants adversely effects and reinforce chemical disruption of the gut microbiome. It highlights the importance of evaluating how environmental contaminants, like pesticides, impact body regulation by gut microbiota. The study has significant implications for considerations that should be, but are not currently, a part of pesticide review and registration by the U.S. Environmental Protection Agency (EPA). Gut microbiota plays a crucial role in lifelong digestion, immune, and central nervous system regulation, as wells as other bodily functions. Through the gut biome, pesticide exposure can enhance or exacerbate, the adverse effects of additional environmental toxicants on the body. Since the gut microbiome shapes metabolism, it can mediate some toxic effects of environmental chemicals. However, with prolonged exposure to various environmental contaminants, critical chemical-induced changes may occur in the gut microbes, influencing adverse health outcomes. Karen Chiu, Ph.D., a graduate research fellow at the […]

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13
May

Pilot Study Links Celiac Disease to Long-Lived Endocrine Disrupting Chemicals, like DDT, in the Environment

(Beyond Pesticides, May 13, 2020) A pilot study at New York University (NYU) provides evidence of a direct relationship between increased risk for celiac disease (adverse immune response to eating gluten) and exposure to endocrine-disrupting chemicals, including DDE – a metabolite of the infamous, bird-killing pesticide DDT. Researchers at NYU set out to elucidate the connection between the autoimmune disease and persistent organic pollutants (POPs), also known as “forever chemicals” or “legacy chemicals” due to their persistence in nature and the human body. The new research, published in Environmental Science, highlights higher odds for celiac disease among participants with elevated POPs exposure and differing results among male and female participants. Considering the complexity of these initial results, researcher Leonardo Trasande, Ph.D. says, “It’s not as if these chemicals were designed with the human body in mind; These chemicals were designed with materials in mind.” [See video overview here] Celiac disease produces an immune-mediated inflammatory response to the consumption of gluten, a protein found in wheat, rye, and barley. Risk for celiac disease has long been associated with genetic factors, but increased prevalence of the disease inspired further research. Considering previous studies on the deleterious impact of POPs on the immune […]

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09
Apr

Honey Bee Queens’ Exposure to Pesticides Weaken Reproductive Success and Colony Development

(Beyond Pesticides, April 9, 2020) Honey bees (Apis mellifera) remain in severe decline, with U.S. beekeepers losing 30% of their managed colonies each year. A Texas A&M University (Dr. Juliana Rangel’s laboratory)  study provides evidence that chemical-intensive farming practices contaminate honey bee hives with pesticides that cause developmental delays. Researchers found that toxic pesticides adversely affect honey bee queen physiology and worker bee performance. Moreover, pesticides exacerbate the health risks associated with the declining honey bee population. When maturing honey bees’ exposure to pesticides is limited, there is an improvement in honey bee queen health and colony behavior. In agricultural settings, honey bees are exposed to an amalgamation of pesticides. AAFC and Texas A&M researchers determined which pesticides (miticides, insecticides, and fungicides) are commonly used in combination and then used those pesticide combinations to expose honey bees to field-realistic doses in the lab: tau-fluvalinate and coumaphos, amitraz, or chlorothalonil and chlorpyrifos. Researchers cultivated maturing honey bee queens in plastic cups coated with either pesticide-free or pesticide-contaminated beeswax. Honey bee queens were transferred into hives upon maturation and bred naturally. Researchers measured their egg-laying frequency along with worker bee entourage size. Post-reproduction, scientists performed a bioassay (a measurement of substance potency or concentration effects on living cells) on […]

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02
Mar

Take Action Today: Tell EPA to Ban Atrazine

(Beyond Pesticides, March 2, 2020) Deadline today! Tell EPA to Ban Atrazine; Protect Children and Frogs from this Endocrine Disrupting Pesticide. Atrazine, the second most-used herbicide in the U.S., is an insidious poison. Atrazine is known for producing developmental abnormalities in frogs. It also affects the endocrine system and reproductive biology of humans. In addition to its agricultural uses on corn, sorghum, and sugar cane, atrazine is also used on home lawns, school grounds, and parks, where exposure to children is common. Nontoxic alternatives are available for all of these uses. Act today, March 2. Sign the petition demanding that EPA ban atrazine and its cousins simazine and propazine. Act today! Beyond Pesticides will submit comments: Docket: EPA-HQ-OPP-2017-0750 (FRL-10002-92) Petition to EPA’s Office of Pesticide Programs: We have serious concerns with the proposed interim decisions on reregistration of three triazine pesticides: atrazine, simazine, and propazine. These triazines are highly mobile and persistent in the environment and have been linked to numerous adverse health and environmental effects which have motivated numerous public interest campaigns to ban their use in the U.S. as well as in Europe. The Draft Ecological Risk Assessments for the Registration Review of Atrazine, Simazine, and Propazine dated October 5, 2016 […]

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29
Jan

Rate of Male Breast Cancer on the Rise in Scotland, Endocrine-Disrupting Chemicals Suspected

(Beyond Pesticides, January 29, 2020) A study of male breast cancer (MBC) in Scotland reports an alarming, increasing trend of this rare disease – especially in agricultural areas. While only accounting for 1% of diagnosed breast cancer, MBC forms in the breast tissue of men and is often fatal because of delayed diagnosis and lack of research on male-specific treatment. The authors point to risk factors that include increased exposure to endocrine-disrupting chemicals, such as pesticides, and a need for further study. Researchers analyzed data from the Information Services Scotland database spanning from 1992-2017. Results showed that incidence of breast cancer in men rose with age, and that the total number and age-adjusted incidence of MBC increased in the last 25 years. Overall, the incidence rose by 38.5%. There was a total of 558 diagnoses in Scotland in the entire period. The trend is clearest in certain regions, including the North of Scotland and some rural areas. “Within the confines of this observational study, reasons for these regional differences are difficult to reconcile, but potential explanations are offered,” the authors write, “Exposure to environmental compounds that mimic oestrogens (so-called Endocrine-Disrupting Chemicals; (EDCs)) might be exacerbated in areas of higher agricultural […]

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15
Jan

Exploratory Study Indicates Pesticide Exposure May Relate to Higher Risk for Endometriosis

(Beyond Pesticides, January 15, 2019) A study published in the journal Environment International, Association of urinary metabolites of organophosphate and pyrethroid insecticides, and phenoxy herbicides with endometriosis, is the first of its kind. Researchers considered the endocrine-disrupting properties of pesticides (such as reduced sperm counts) and investigated whether there might be a relationship between pesticide exposure and endometriosis. Endometriosis is an estrogen-dependent gynecologic disease that affects about 176 million women globally. It can cause extreme pain and infertility as well as increased risk for cancer and cardiovascular diseases. This study finds a positive correlation between some pesticide metabolites and endometriosis, though authors encourage further study to corroborate the findings. Researchers examined exposure to 11 “universal pesticides” and their metabolites and its relationship to endometriosis in 492 reproductive-age women recruited from 14 surgical centers in Utah and California from 2007-2009. The women at these clinics were scheduled for laparoscopy or laparotomy—the “gold standard” for identifying endometriosis is through these surgeries. The study compares results from the clinical cohort to a group of women in the same age bracket from areas surrounding the participating clinics. 619 urine samples were analyzed from the operative and population cohorts. This study detected six of the […]

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10
Jan

Study Links Pyrethroid Insecticides to Cardiovascular Disease and Other Health Hazards

(Beyond Pesticides, January 10, 2020) A new study by researchers out of the University of Iowa College of Public Health, published in JAMA (the Journal of the American Medical Association) Internal Medicine, demonstrates that greater exposure to pyrethroid insecticides is associated with higher risks of death from all causes and from cardiovascular disease. These compounds can be inhaled, ingested, or absorbed through the skin; they are highly neurotoxic, and have also been linked to certain cancers, endocrine disruption, and suppression of the immune system, as well as respiratory and reproductive impacts. The researchers gathered data, for 2,116 adults aged 20 or older, from the National Health and Nutrition Examination Survey. Each of those subjects had contributed a urine sample at some point between 1999 and 2002. Urine samples reflect levels of a pyrethroid metabolite (3-phenoxybenzoic acid) present, which in turn offer information about pyrethroid exposure. The researchers followed the participants until 2015; the research analysis was performed in the summer of 2019. Data were adjusted to accommodate multiple factors (age, sex, ethnicity, socioeconomic status, diet and lifestyle, smoking status, body mass index, and urinary creatinine levels). The co-authors report that subjects with the highest levels of metabolites had a 56% […]

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03
Jul

Triclosan Exposure Linked to Osteoporosis among U.S. Women

(Beyond Pesticides, July 3, 2019) A disturbing association between urinary triclosan concentrations and osteoporosis has been identified in an epidemiological study. Drawing from the National Health and Nutrition Examination Survey (NHANES) results for 1,848 U.S. adult women, the authors conclude that higher concentrations of urinary triclosan are associated with lower bone mass density and higher prevalence of osteoporosis among U.S. adult women. The study, published in the Journal of Clinical Endocrinology and Metabolism, adds weight to previous laboratory results, which showed that endocrine-disrupting chemicals such as triclosan can interfere with bone metabolism. Triclosan and its byproducts are known endocrine disruptors and have been shown in laboratory studies to interfere with collagen and bone structure. Taken together with previous findings, the new epidemiological results demonstrate that the ubiquitous endocrine disruptor triclosan “could lead to lower BMD [benchmark dose] and increased prevalence of osteoporosis in U.S. adult women.” Triclosan is used as an antimicrobial agent in products regulated by both the Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA), and cumulative exposure to triclosan registered by both agencies pose unacceptable risks to human health and the environment. Triclosan exposure has become so common that it has shown up in […]

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01
Jul

Act on EPA’s Failure to Regulate Endocrine Disruptors, which Threatens Public Health

(Beyond Pesticides, July 1, 2019) France made a decision in May to ban a widely-used fungicide because it damages the endocrine system. In contrast, there has been a stark failure to protect health in the U.S. Despite a Congressional mandate, EPA is not acting on endocrine disruptors linked to infertility and other reproductive disorders, diabetes, cardiovascular disease, obesity, and early puberty, as well as attention deficit hyperactivity disorder (ADHD), Parkinson’s, Alzheimer’s, and childhood and adult cancers. This is a tragedy. Ask your elected members of Congress to demand that EPA tests and acts on regulatory endocrine disruptors as required by law. In 1998, following a mandate in the Food Quality Protection Act (FQPA) of 1996, EPA established a program to screen and test pesticides and other widespread chemical substances for endocrine disrupting effects. Despite operating for 21 years, the Endocrine Disruptor Screening Program (EDSP) has made little progress in reviewing and regulating endocrine-disrupting pesticides.  As of 2019, the program has stalled entirely. To ensure appropriate follow-through, Congress gave EPA a timeline to: develop a peer-reviewed screening and testing plan with public input not later than two years after enactment (August 1998); implement screening and testing not later than three years after […]

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07
Jun

Study Documents Playgrounds Contaminated with Pesticides from Neighboring Chemical-Intensive Ag Land

(Beyond Pesticides, June 7, 2019) Fruit orchards and vineyards endure some of the most intensive chemical management in all of agriculture. What has not been investigated — until now — is how pesticide drift from such agricultural sites may be affecting nearby public spaces. A recent, first-of-its-kind study out of northern Italy tested 71 public playgrounds near to apple orchards and vineyards in four valleys of the North Tyrol, and finds that 45% are contaminated with a single pesticide, and 24% by more than one. Study authors note that the playground contamination will likely grow worse over the course of the growing season. This would likely amplify the impacts of such chemical trespass on nearby public spaces, never mind the varieties of harm to the sites themselves and the food produced on them. Organic agriculture, of course, remedies all these concerns. The study randomly chose 71 public playgrounds in the four South Tyrolean regions, and analyzed grass samples for potential contamination by 315 different pesticides. Because pesticides applied to agricultural fields, orchards, and vineyards are easily volatized, carried aloft by wind, and/or washed by rain off of the target site, the study also evaluated the impacts of those (and other) factors […]

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02
May

Neonicotinoid Insecticide Residues in Food and Water on the Rise, According to USDA Data

(Beyond Pesticides, May 2, 2019) Researchers have documented an increase in food and drinking water residues of neonicotinoids, insecticides linked to breast cancer. Using the Pesticide Data Program (PDP), 1999-2015, of the U.S. Department of Agriculture, the researchers identified near-peak detection frequencies in 2015, after a decline from 2008-2013. Imidacloprid remains the most common neonicotinoid detected across imported commodities, while the neonicotinoids clothianidin, thiamethoxam, acetamiprid, and flonicamid are replacing imidacloprid in domestic production. Authors note that these newer neonicotinoids are potentially more toxic than imidacloprid, raising concerns for understudied human health and environmental impacts. The study, Trends in neonicotinoid pesticide residues in food and water in the United States, 1999–2015, published in the journal Environmental Health, finds the highest detection frequencies for neonicotinoids in drinking water, with 30% of treated drinking water turning out positive for imidacloprid in 2011. Certain fruits and vegetables are also frequently contaminated by neonicotinoids, with detection frequencies ranging from 20% to as high as 57% in the case of imidacloprid on cauliflower. While the study points to specific fruits and vegetables as posing higher risk, the main message reaches beyond individual commodity or individual neonicotinoid results. Authors uncover a systematic increase in detection of neonicotinoid […]

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26
Apr

Study Finds High Levels of Pesticide Exposure among Teenage Girls in California’s Salinas Valley

(Beyond Pesticides, April 26, 2019) Research by the youth participatory action team of the CHAMACOS of the Salinas Evaluating Chemicals in Homes and Agriculture (COSECHA) reveals that teenagers in the Salinas Valley, California are routinely exposed to concerning levels of multiple toxic pesticides, several of them known endocrine disruptors. In an interview with Kion News, COSECHA research director Kimberly Parra remarked that the study is especially important because teenagers are in a stage of rapid reproductive development. As the study authors emphasize, it is their developmental stage that makes teenagers more vulnerable to the effects of endocrine disrupting pesticides, with potentially devastating consequences for lifelong health. The COSECHA study quantifies exposure to 72 pesticides, captured through volatile-trapping silicone wristbands, across 97 teenage girls living in various areas of the Salinas Valley region. Of the 72 pesticides analyzed, authors report that subjects are exposed to as many as 20 and an average of 8 pesticides over one week of routine indoor and outdoor activity. Given the well-documented dangers of pesticide co-exposures, these multiple-exposure findings are particularly concerning. Ranking the highest for prevalence among the studied pesticides is fipronil sulfide, a breakdown product of the insecticide fipronil, detected in 86.6% of the analyzed wristbands. […]

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07
Mar

Bee-Toxic Neonicotinoid Insecticide Exposure Linked to Hormone-Dependent Breast Cancer

(Beyond Pesticides, March 7, 2019) A publication in the journal Environmental Health Perspectives highlights findings from a recent study showing that environmental concentrations of the neonicotinoid insecticides thiacloprid and imidacloprid increase expression of a gene linked to hormone-dependent breast cancer. Authors of the featured study uncovered a pathway through which neonicotinoids stimulate excess estrogen production, known to occur during the development of progressive hormone-dependent breast cancer. In the words of the authors, “Our findings highlight the need for further research to assess the potential impacts of low-dose and chronic exposure to neonicotinoids on endocrine processes affecting women’s health.” The study, published in Environmental Health Perspectives in April 2018 by researchers at the University of Quebec, is not the first to point to a potential link between neonicotinoid exposure and breast cancer. A 2015 study by the same research group revealed that the neonicotinoids thiacloprid and thiamethoxam, along with the herbicide atrazine, induce similar effects in breast cancer cells. In both studies, exposure to neonicotinoids alter promoter activity to induce heightened production of the enzyme aromatase, which is known to stimulate estrogen production and thereby cancer cell proliferation. The recently published study, authored by Silke Schmidt, PhD, brings greater urgency to […]

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