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Daily News Blog

Archive for the 'Women’s Health' Category


16
Sep

Persistent Organic Pollutants, including Banned Pesticides, Remain Present in all Fetal Organs Regardless of Maternal Chemical Contamination

(Beyond Pesticides, September 16, 2021) A study published in Chemosphere finds persistent organic pollutants (POPs), including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs), are present in the serum and placenta of pregnant mothers, as well as multiple fetal organs. Many studies indicate prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. However, this study is one of the first to demonstrate the presence of chemical toxicants in fetal tissue that are not present in maternal serum or placental samples. Prenatal development is one of the most vulnerable periods of exposure when the fetus is most susceptible to the harmful effects of chemical contaminants. Therefore, studies like these help government and health officials better identify fetal exposure contaminants and subsequent health concerns otherwise missed by current chemical monitoring methods. The researchers note, “These findings call for further evaluation of the current matrices used to estimate fetal exposure and establish a possible correction factor for a more accurate assessment of exposure in utero. We disclose the full data set on individual exposure concentrations to assist in building in silico models for prediction of human fetal exposure to chemicals.” Several studies associate early-life exposure to toxic chemicals […]

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01
Sep

In Utero and Childhood Pesticide Exposure Increases Childhood Cancer Risk

(Beyond Pesticides, September 1, 2021) A study published in Environmental Pollution finds the risk of acute childhood leukemia (AL) increases with prenatal and newborn exposure to pesticides (i.e., insecticides and herbicides). The study results support the hypothesis that chronic environmental pesticide exposure increases childhood leukemia risk up to two times. Maternal exposure has a stronger association with leukemia than childhood exposure. Insecticides and herbicides are of particular significance in increasing leukemia risk, especially for acute lymphoblastic leukemia. Although medical advancements in disease survival are more prominent nowadays, childhood AL remains the secondary cause of child mortality following physical injury. Furthermore, childhood leukemia survivors can suffer from chronic or long-term health complications that may be life-threatening. Although the etiology or cause of childhood AL involves the interaction of multiple components like lifestyle and genetics, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, pesticides, solvents, diet, etc.) play a role in disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues resulting in chronic health effects. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Already, studies find low levels of pesticide exposure during […]

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10
Jun

Women’s Exposure to Environmental Pollutants Prompts Infertility and Low Egg Count

(Beyond Pesticides, June 10, 2021) Exposure to toxic chemicals decreases egg count and increases infertility risk among women, according to a study published in Environment International. Since 2014, U.S. fertility rates have been decreasing, with many attributing the decline to older age pregnancies. However, several findings demonstrate that exposure to environmental pollutants, like persistent organic pollutants (POPs) from the industrial and agriculture industry, contributes to a decline in fertility rates. Scientists and health officials already associate exposure to POPs, like pesticides, with adverse impacts on male fertility, including reduced sperm count, quality, and abnormal sperm development. Therefore, it is essential to understand how exposure to toxic chemicals in the environment affects reproductive success, especially among women who can transfer contaminants to the fetus via the umbilical cord. The researchers note that these findings should urge government and health officials to reexamine chemical safety concerning reproductive health, and “strongly encourage [them] to study mechanisms behind POP-associated infertility in women in more detail.” Researchers examined ovarian egg reserve size in pregnant women directly by examining the density of follicles and immature eggs in ovarian tissue and indirectly via serum anti-MĂĽllerian hormone (AMH). Using AMH serum samples, researchers assessed concentration levels of 31 POPs: nine organochlorine pesticides (OCPs), ten polychlorinated […]

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22
Apr

Grandmother’s Exposure to DDT Increases Granddaughters’ Breast Cancer and Cardiometabolic Disorder Risk

(Beyond Pesticides, April 22, 2021) Past maternal exposure to the pesticide dichlorodiphenyltrichloroethane (DDT) during pregnancy can increase the risk of breast cancer and cardiometabolic disorders (e.g., heart disease, obesity, diabetes) up to three successive generations, according to a new study published in Cancer Epidemiology, Biomarkers & Prevention. Although previous studies highlight early life or in utero exposure to DDT increasing breast cancer risk later in life, this study is the first to note generational effects on grandchildren’s health. DDT continues to adversely affect the health of the U.S. population, nearly 50 years after its ban. However, this ban is not global, as many countries still use or manufacture the chemical compound. Furthermore, residues of DDT metabolite, DDE, continue to readily contaminate food and water worldwide. Therefore, studies like these highlight the need to investigate how first-generation pesticide exposure can impact future generational health in order to prevent adverse health outcomes, especially during sensitive developmental periods (i.e., in utero, infancy/childhood). The study researchers note, “Discovery of actionable biomarkers of response to ancestral environmental exposures in young women may provide opportunities for breast cancer prevention.” To assess the association between multi-generational health risks and chemical exposure, researchers used the Public Health Institute’s Child […]

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15
Apr

Exposure to PFAS—the “Forever” chemical—During Pregnancy Results an Increase in Heart and Metabolic Problems Among Adolescence

(Beyond Pesticides, April 15, 2021) Gestational (during pregnancy) and childhood exposure to per- and polyfluoroalkyl substances (PFAS) increase cardiometabolic risk, or the risk of heart diseases and metabolic disorders, later in life, according to a Brown University study published in Environment International. Past studies associate exposure to chemical pollutants with increased susceptibility to adverse health effects during critical fetal and childhood developmental periods. Some of these health effects are cardiometabolic risk factors, including obesity, insulin issues, abnormal blood pressure, that increase the risk of developing cardiovascular disease (CVD) and metabolic disorders (e.g., type 2 diabetes). PFAS are of particular concern as these endocrine-disrupting chemicals are common in non-stick cookware, cleaning/personal care products, food packaging, and other consumer products. They are now being found in pesticide products. Because of their ubiquitous use in many products, studies report that PFAS compounds are detectable in infants, children, and pregnant women. Furthermore, pregnant women can readily transfer compounds to the developing fetus through the placenta. Cardiovascular disease and diabetes are among the leading causes of death globally. Additionally, heart conditions are one leading cause of disability in the U.S., as research demonstrates environmental pollutant exposure can increase the risk of developing cardiovascular disease, including stroke, heart attack, heart failure, atrial fibrillation, and cardiac […]

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25
Mar

Over 100 Chemicals Detectable in Pregnant Women, Including 98 “New” or Unknown Compounds

(Beyond Pesticides, March 25, 2021) A new University of California San Francisco (UCSF) study, published in Environmental Science & Technology, finds over 100 chemicals present in U.S. pregnant women’s blood and umbilical cord samples. This discovery ignites concerns over prenatal exposure to chemicals from consumer and industrial products and sources. Furthermore, 89 percent of these chemical contaminants are unknown sources and uses, lacking adequate information, or are not previously detectable in humans. This discovery ignites concerns over prenatal exposure to chemicals from consumer and industrial products and sources. A National Health and Nutrition Examination Survey (NHANES) finds U.S. pregnant women experience frequent exposure to environmental pollutants that pose serious health risks to both mother and newborn. Many known environmental pollutants (i.e., heavy metals, polychlorinated biphenyl, and pesticides) are chemicals that can move from the mother to the developing fetus at higher exposure rates. Hence, prenatal exposure to these chemicals may increase the prevalence of birth-related health consequences like natal abnormalities and learning/developmental disabilities.  Current chemical biomonitoring methods only analyze a targeted few hundred chemicals—a small portion of the over 8000 chemicals the U.S. manufactures and imports. However, this study employs new technology that identifies a more comprehensive range of industrial chemicals. Therefore, research like this is essential for future […]

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18
Mar

Common Use Organophosphate Insecticides Pose a Greater Threat to Women’s Health

(Beyond Pesticides, March 18, 2021) A new study published in Environmental Toxicology and Pharmacology finds chronic (long-term) organophosphate (OP) pesticide exposure increases adverse health and cancer risk for U.S. women relative to men. Organophosphorus pesticides have a wide range of biological uses—from insecticides to flame retardants—that make these chemicals ubiquitous, significantly contributing to ecosystem contamination. Furthermore, while organophosphates have less bioaccumulation potential, residues are consistently present in human and animal blood, urine, tissues, and milk. Although research demonstrates that OPs are highly toxic, there remains an inadequate understanding of how OP exposure impacts the nonagricultural population in the U.S., especially women. Therefore, it is essential to investigate the sex-specific health effects chemical contaminants can produce to mitigate exposure among vulnerable populations. Study researchers note, “Given the higher burden of OP exposure and their significantly higher overall health risk, including cancer, reducing OP exposure in U.S. women needs to be prioritized.” To examine the relationship between OP exposure and health risks, researchers investigated the presence of commonly detected OP metabolite concentrations in urine using participants from the U.S. National Health and Nutrition Examination Survey (NHANES). Urine samples measure OP metabolite as an indicator of OP exposure like previous agriculture-related population surveys. Study participants report health issues […]

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