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Daily News Blog

Archive for the 'Amyotrophic Lateral Sclerosis (ALS)' Category


28
May

Occupational Exposure to Pesticides, and Other Environmental Chemicals Increase Risk of Developing ALS

(Beyond Pesticides, May 28, 2020) Exposure to agricultural and industrial pesticides, solvents (thinners), electromagnetic fields, and heavy metals predispose humans to amyotrophic lateral sclerosis (ALS), according to an Italian research study, “Environmental and Occupational Risk Factors of Amyotrophic Lateral Sclerosis: A Population-Based Case-Control Study,” published in the International Journal of Environmental Research and Public Health. Although research supports ALS’s genetic etiology, epidemiologic research associating ALS risks and to environmental, or work-related risk factors (i.e., pesticide use, pollutant exposure, heavy metal exposure, etc.) has been inconsistent and non-definitive. This research demonstrates the importance of assessing aggregate health risks associated with occupational pesticide exposure, especially when determining potential exposure routes in specific occupational sectors. In the study, researchers note, “In particular, having an occupation in the agricultural sector, especially with a long duration of the working activity as well as occupational exposure to some chemicals…might increase ALS risk.” While scientists extensively study the epidemiology of amyotrophic lateral sclerosis (ALS)—a rare, yet fatal neurodegenerative disease—occupational and environmental hazards inducing random (sporadic) or hereditary ALS diagnoses remain vague. With researchers predicting a global ALS incidence increase of 69% by 2040, identifying ALS’s causal factors are important to future research. In this research, Italian researchers conducted a case-control, […]

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16
May

Exposure to Pesticides Linked to ALS Risk

(Beyond Pesticides, May 16, 2016) Pesticide exposure may increase the risk of amyotrophic lateral sclerosis (ALS), according to a study entitled Association of Environmental Toxins With Amyotrophic Lateral Sclerosis, which was  published in JAMA Neurology. ALS, also known as Lou Gehrig’s disease, is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. The study, which investigated a total of 122 persistent environmental pollutants, including organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and brominated flame retardants (BFRs), found that pesticide exposure increased ALS risk five-fold. Researchers conducting the study  looked at 156 patients with ALS and 128 without the disease. Participants were asked about occupational and residential exposure to environmental toxicants  and blood samples were taken to measure their concentrations. Researchers found that the organochlorine pesticides pentachlorobenzene and cis-chlordane increased ALS risk two-fold and nearly six-fold, respectively. This study does not prove that pesticides cause ALS, but it does build on an association suggested in previous research, study co-author Stephen Goutman, MD, told  HealthDay. Dr. Goutman recommends avoiding pesticides. This is especially wise for anyone with a family history of ALS, he added. The link between pesticide exposure and neurological damage has been studied extensively. In 2008, […]

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