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Daily News Blog

Archive for the 'Autism' Category


26
Aug

Review of Science on Glyphosate Weed Killer in Poultry Production Highlights Extraordinary Health Threats

(Beyond Pesticides, August 26, 2025) A scientific review in World’s Poultry Science Journal highlights the adverse health effects on avian species from exposure to the widely used weed killer glyphosate (Roundupᵀᴹ) throughout the process of poultry production. The herbicide enters the poultry production system through residues in genetically engineered feed. An earlier article in Scientific Reports concludes that glyphosate’s (GLP) “widespread application on feed crops leaves residues in the feed,” while residues are “found to be common in conventional eggs acquired from grocery stores.” In analyzing the biochemical, toxicological, and ecological impacts of glyphosate on poultry, particularly chickens, the authors find a wide body of evidence linking glyphosate and its metabolite (breakdown product) aminomethylphosphonic acid (AMPA) to debilitating hazards that extend beyond mortality. These sublethal effects include disruption of the gut microbiome and gastrointestinal disease; decreased productivity and diminished reproductive health; hepatic and kidney toxicity; growth and developmental impacts, including teratogenicity and embryotoxicity; endocrine disruption and oxidative stress; and impaired immune functions. The effects of glyphosate, as have long been documented in the scientific literature and covered by Beyond Pesticides here, range from negative impacts on biodiversity and the environment to food safety risks and human health implications. Residues of […]

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19
Aug

Biomonitoring of Total Pesticide Exposure Shows Adverse Effects to Women’s Reproductive Health

(Beyond Pesticides, August 19, 2025) A new study from Argentina highlights the importance of applying the concept of the exposome (total exposures over lifetime) as a scientific framework, the value of biomonitoring, and findings of adverse pregnancy outcomes. The study documents the presence and effects of pesticides on maternal and fetal health during pregnancy. The results show that pregnant Argentine women are exposed to dozens of pesticides, and that certain mixtures of these chemicals are associated with harm to pregnancy outcomes, especially among rural women. The exposome, the authors write, comprises the “non-genetic factors that may be involved in the development or aggravation of human disease. The prenatal exposome includes all environmental chemicals that the mother is exposed to during pregnancy (maternal exposome) and those chemicals that reach the placenta and fetus from the maternal circulation (fetal exposome).” The authors emphasize that understanding the exposome almost by definition requires studying mixtures of environmental chemicals rather than analyzing the effects of each in isolation. The second important aspect of the study is its use of biomonitoring. The researchers analyzed urine samples from 90 pregnant women in various gestational stages from rural and urban regions of Argentina. The researchers also collected demographic […]

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14
Aug

Review Links Pesticides and Contaminants to Mechanisms that Threaten Women’s Reproductive Health

(Beyond Pesticides, August 14, 2025) A review in Clinical and Experimental Obstetrics & Gynecology links various classes of environmental pollutants including pesticides and per- and polyfluoroalkyl substances (PFAS), both of which Beyond Pesticides has extensively covered, to adverse effects on the female reproductive system and common mechanisms of toxicity. These chemicals “disrupt the hypothalamic-pituitary-gonadal axis (HPG), impair ovarian function, and contribute to reproductive dysfunction through mechanisms such as oxidative stress, hormonal disruption, and epigenetic [gene expression or behavior] modifications,” the authors say. This leads to menstrual irregularities, infertility, and pregnancy complications, as well as increases in the risk of reproductive system disorders such as endometriosis, polycystic ovary syndrome (PCOS), and ovarian cancer, among others. “Additionally, transgenerational effects mediated by epigenetic modifications, germ cell damage, and placental transfer may adversely affect offspring health, increasing the risk of reproductive dysfunction, neurodevelopmental disorders, metabolic diseases, and cancer,” the researchers explain. This study, integrating recent epidemiological and experimental findings, provides an overview of major chemical classes that threaten women’s health and highlights the need for immediate action. As the authors point out, female reproductive health is important not only for those who choose to plan for a family but also for the overall well-being […]

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25
Jul

Research Finds Heightened Toxicity to Aquatic Organisms from Microplastic–Pesticide Interactions

(Beyond Pesticides, July 25, 2025) The scientific literature shows that microplastics (MPs) and pesticides, both ubiquitous throughout the environment, have synergistic effects that threaten aquatic organisms. This means the combined toxicity of the two substances is greater than the sum of two individual exposures. The most recent study to demonstrate this, published in Ecotoxicology, focuses on the impacts of MPs and chlorpyrifos (CPF), a widely used organophosphate insecticide, on cladocerans, a group of microcrustaceans. As Beyond Pesticides has previously reported, microplastics are found in all environments and threaten not only human health but all wildlife in both aquatic and terrestrial ecosystems. The universal distribution of plastics means that they cannot be avoided. Humans and other organisms take up plastics in the form of microparticles and nanoparticles by inhalation, ingestion, and skin contact every day. Microplastics are about the width of a human hair; nanoplastics are much smaller, about twice the width of a DNA strand. Larger pieces of plastic are ground down to these tiny sizes by weathering, temperature, biological processes, and chemical conditions. (See additional Daily News coverage on the health and environmental hazards of plastics here, here, and here.) The authors of the current study, in exposing two […]

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22
Jul

Womb to Menopause: Endocrine Disrupting Chemicals’ Effects on Reproductive Health

(Beyond Pesticides, July 22, 2025) A study published in May by Nature Reviews Endocrinology warns that endocrine-disrupting chemicals (EDCs)—substances that lead to disruption of the endocrine system in an organism—are driving a rapid rise in female reproductive disorders. While EDCs encompass many different forms of chemicals, such as plastic additives, cigarette smoke, and paracetamol, pesticides are among the most common EDCs. The review pays special attention to pesticide classes such as per-and polyfluoroalkyl substances (PFAS) and organochlorines to evaluate how they derail ovarian development, puberty timing, and hormonal balance across the entire female lifespan. Many pesticides are fluorinated, and therefore classified as PFAS.  Background  Pesticides represent one of the largest sources of EDC exposure. Many persistent organic pollutants (POPs) are resistant to degradation and are capable of bioaccumulating in the food chain, which leads to these harmful chemicals being found in human adipose tissue. The study notes that these chemicals have also been detected in human blood, breast milk, follicular fluid, and other biological samples, explaining their prevalent presence in the human body. The review emphasizes that humans are exposed to a mixture of EDCs across their lifespan, yet current U.S. regulatory strategies do not fully account for combined lifetime […]

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27
Jun

Wide Use of Paraquat in Suicides Adds to Herbicide’s Threats and Call for Ban

(Beyond Pesticides, June 27, 2025) An article in The New York Times (NYT), entitled “A Killer Within Easy Reach,” highlights the use of the weed killer paraquat, a widely used herbicide in the U.S. and many other parts of the world despite being banned in over 70 countries, as the cause of numerous suicides. The article references the tiny nation of Suriname, located on the northeastern coast of South America, as they have “one of the highest suicide rates in the world,” with the majority of those deaths involving paraquat. Globally, paraquat is prevalently used in self-harm incidents. The chemical, when absorbed into the body, among other deadly effects, causes pulmonary fibrosis, making lung tissue brittle and causing respiratory failure. While this pesticide is intended and generally used for weed control, it is also highly lethal to humans in small amounts and is often easily accessible in many households. As the NYT article states, “Pesticides are among the leading means of suicide in agricultural areas of developing nations, implicated in more than 100,000 deaths annually.” Citing examples from around the world, the article states, “Sri Lanka’s crop yields had surged after the introduction of modern fertilizers and pesticides in the […]

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25
Jun

Toxic Chemicals Detected in Common Menstruation Products

(Beyond Pesticides, June 25, 2025) A United Kingdom (UK) study, published in May by the Women’s Environmental Network (Wen) and Pesticide Action Network (PAN) UK, is reporting levels of the herbicide glyphosate—a probable human carcinogen that is also linked to Parkinson’s disease—in tampons at concentrations 40 times higher than the legal drinking water limit. This finding highlights the serious public health threats that result from under-regulated period products, given that 1.8 billion people worldwide menstruate monthly, according to UNICEF.   The report raises fundamental concerns about the harm to women’s health associated with toxic chemical exposure. For tampon users, the vaginal route of exposure bypasses detoxification with a significantly higher absorption rate than skin. In addition, health concerns extend to ongoing chronic toxic chemical exposures to women worldwide working in cotton production and living in nearby communities. Methodology To investigate whether menstrual products contain harmful pesticide residues and whether current safety standards adequately control the risk of vaginal exposure, study researchers tested 15 boxes of tampons directly bought from UK supermarkets. These boxes were sent to an external laboratory for testing that looks for the presence of glyphosate and its breakdown product amionomethylphosphoric acid (AMPA) in the cotton material used to […]

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19
Jun

This Juneteenth, Support Efforts for Environmental Justice by Eliminating Pesticide Use

(Beyond Pesticides, June 19, 2025) Juneteenth, officially recognized as a federal holiday since 2021, commemorates the arrival of Union soldiers in Galveston, Texas, to free enslaved people per the Emancipation Proclamation that was issued two and a half years prior. While June 19, 1865, does not mark the legal end of slavery nationwide, it was a crucial moment in the fight for freedom and continues to highlight the ongoing fight for human rights, equality, and environmental justice.   As Beyond Pesticides has previously shared in the Daily News, this commemorative day is a time for individuals and organizations to acknowledge and reflect on their past and current actions or inactions that perpetuate systemic racism. The father of environmental justice, Robert Bullard, Ph.D., defines environmental racism as any policy or practice that unequally affects or disadvantages individuals, groups, or communities based on their race. Dr. Bullard states that, until the 1980s, environmental conservation and pollution were separate. Many environmental organizations prioritized the preservation of “wilderness” rather than urban areas, predominantly comprised of POC, who continuously experience the disproportionate impacts of pollution and the effects of environmental racism.   Sharing the Science  A recent study regarding the intersections of urban planning, wildlife management, […]

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26
May

On Memorial Day, Remember the Lives Lost and Those Still Fighting the Effects of Military Pesticide Use

(Beyond Pesticides, May 23-26, 2025) This Memorial Day, while honoring and mourning the U.S. military personnel who have died serving in the United States Armed Forces, Beyond Pesticides recognizes those who are still fighting the long-term impacts of exposure to toxic chemicals as a result of their use in warfare. A recent review in the Open Journal of Soil Science acts as a reminder of the effects that span multiple generations to both the environment and human health following the use of pesticides. The review analyzes the history and impacts of herbicide use during the Vietnam War, as well as emphasizes the importance and relevance for current and future generations. As the authors state, “The United States (U.S.) and other countries, including Russia and Ukraine, need to learn the historical lessons from the U.S. use of herbicides, containing dioxin TCDD and/or arsenic (As), as chemical weapons during the Vietnam War.” As previously reported by Beyond Pesticides, public attention generally focuses on the “rainbow herbicides,” particularly Agent Orange, used during the Vietnam War; meanwhile, it is the dioxin TCDD (2,3,7,8 tetrachlorodibenzodioxin), a byproduct of Agent Orange’s manufacturing process, that has caused the most lasting damage within the country. While the breakdown […]

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25
Apr

Male Fertility and Reproduction in Bee Species Threatened with Systemic Insecticide Exposure, Study Finds

(Beyond Pesticides, April 25, 2025) A novel study in Chemosphere finds impacts on male fertility in a bee species (Osmia bicornis) with exposure to sulfoxaflor, a systemic sulfoximine insecticide with similar mechanisms to neonicotinoids. “For the first time, we demonstrate that short-term chronic, field-realistic exposure to a common pesticide reduced pre-copulatory display (36%) and sounds (27%) [courtship behaviors], increased the number of copulations (+110%) and the mating duration (+166%), while finally reducing sperm quantity (25%) and mating success (43%),” the researchers report. They continue, “Our research raises considerable concern on the impact of field-realistic, low sublethal pesticide levels on the fertility and reproductive success of pollinators.” Mating behaviors and the ability to successfully reproduce determines the survival of species. As the authors state: “Mating disorders may therefore contribute to the recent decline in insect and pollinators’ health worldwide. While the impact of pesticides on pollinators is widely considered as a driving factor for reducing pollinators’ health, their effect on mating behaviour and male fertility remains widely overlooked.” The red mason bee (O. bicornis) can “provide essential pollination service for both crops and wild plants sustaining food production and biodiversity while serving as a bioindicator of environmental health.” The abundance and […]

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17
Apr

Findings Show Endocrine-Disrupting Glyphosate Weed Killer Threatens Women’s Reproductive Health

(Beyond Pesticides, April 17, 2025) A literature review in Reproductive Sciences finds glyphosate (GLY) and glyphosate-based herbicides (GBH) impact women’s reproductive health, adding to the long list of documented harm from this widely used weed killer. The authors note, “Considering the widespread use of GLY, the controversy regarding its endocrine-disrupting potential and reproductive toxicity, and the innumerable lawsuits filed against Bayer and Monsanto by consumers for morbidities related to Roundup™ exposure, the purpose of this review is to summarize the current literature on the potential adverse effects of GLY and GBHs on the female reproductive tract and discuss possible clinical implications on reproductive health outcomes, including polycystic ovarian syndrome (PCOS), endometriosis, and female fertility.”  Glyphosate and aminomethylphosphonic acid (AMPA), the primary metabolite (breakdown product) of GLY, are found throughout the environment in soil and water, as well as in samples of blood, urine, seminal plasma, and breast milk. Studies have detected residues in farmworkers, as well as “in the urine of 60–80% of the general public in the USA, including pregnant women and children.” (See studies here, here, and here.) The ubiquitous use of GLY and GBH, and subsequent persistence, threatens the health and well-being of all.  Previous studies have […]

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08
Apr

Literature Review of Over 200 Studies Highlights Pesticide Threats to Women’s Reproductive Health

(Beyond Pesticides, April 8, 2025) A comprehensive literature review in Environment & Health analyzes evidence from human biomonitoring, epidemiological studies, and toxicological studies that link adverse effects on women’s reproductive health, specifically impacting the ovary, to pesticide exposure. In examining the scientific literature, consisting of over 200 studies performed in the last 25 years, the authors find pesticide exposure threatens women’s health through ovarian dysfunction. “Epidemiological studies have shown that pesticide exposures are associated with early/delayed menarche [first occurrence of menstruation], menstrual cycle disorders, early menopause, long time to pregnancy, polycystic ovary syndrome, primary ovarian insufficiency, infertility, and implantation failure in women,” the researchers state. They continue, “Both in vivo [in animals] and in vitro [in cells] studies have shown that exposure to pesticides disrupts the estrous cycle, reduces the follicle pool, alters hormone levels, and impairs oocyte [egg] maturation.” These reproductive implications are noted with many different classes of pesticides, such as insecticides, including organochlorine pesticides (OCPs), organophosphates (OPs), pyrethroids, and neonicotinoids, as well as herbicides and fungicides. The authors, however, comment on present research gaps: “Much of the available epidemiological evidence focuses on legacy insecticides, such as OCPs, and a subset of insecticides that are still in use […]

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03
Apr

Research Spotlights New Hazard Severity of Chlorpyrifos, Ag Insecticide Widely Found in Food Supply

(Beyond Pesticides, April 3, 2025) As highlighted by Beyond Pesticides in recent comments to the U.S. Environmental Protection Agency (EPA), chlorpyrifos (CPF) has been under scrutiny for decades due to associated adverse health effects, noted particularly in the extensive and consistent scientific evidence of neurotoxic dangers to children’s health. The latest research on CPF, published in Environmental Toxicology and Genes & Diseases, reveals additional threats to the immune system and male reproduction that are not captured in current EPA risk assessments of chlorpyrifos and raises serious health questions, given that residues are found throughout the food supply. CPF, a widely used organophosphate insecticide in agriculture, is a cholinesterase inhibitor that binds irreversibly to the active site of an essential enzyme for normal nerve impulse transmission, acetylcholine esterase (AChE), inactivating the enzyme. Many insecticides, including organophosphates and carbamates, target AChE, causing them to be highly toxic to both insects and mammals that have this enzyme as a crucial part of their nervous systems. The history of chlorpyrifos exemplifies the failure of pesticide law and policy, as this chemical, among many others, not only has direct adverse health effects but is contributing to the climate crisis, biodiversity collapse, and disproportionate levels of […]

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02
Apr

Study Finds Reproductive System Effects in Adolescents with Prenatal Pesticide Exposure

(Beyond Pesticides, April 2, 2025) In examining prenatal residential proximity of documented pesticide spraying in California to the menstrual cycle characteristics of 273 Latina adolescents, researchers report in the American Journal of Epidemiology a positive association between exposure to the insecticide methomyl and heavy bleeding. Other pesticides appear to influence menstrual symptoms as well. “Adolescents’ menstrual cycle characteristics can be ‘vital signs’ of health and impact quality of life,” the authors share. They continue, “To our knowledge, this is the first study to examine the association between prenatal pesticide exposure and menstrual outcomes in adolescents of any demographic group.” Menstrual cycle characteristics, such as dysmenorrhea (painful or uncomfortable menstrual cramps), irregularity, and heavy menstrual bleeding, can also be indicators of underlying health conditions, including endometriosis, polycystic ovary syndrome (PCOS), thyroid dysfunction, and bleeding disorders. By associating the pesticide exposure of mothers during pregnancy to impacts on their children, the researchers highlight important health risks for women and young girls that are often disregarded. “The prenatal period is a critical period of reproductive development that may be particularly sensitive to endocrine disruption,” the researchers share. As previously reported by Beyond Pesticides, endocrine-disrupting chemicals are any synthetic or natural compounds that hinder […]

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11
Mar

Study Finds Spermiotoxicity and Impacts on Male Mammal Fertility with Ipconazole Fungicide Exposure

(Beyond Pesticides, March 11, 2025) A study in Toxics analyzes ipconazole, a triazole fungicide often used as a coating on treated seeds and as a foliar treatment on the leaves of plants. “Triazole pesticides are widely used throughout the world, but their abuse causes toxic effects in non-targeted organisms,” the researchers state. In the current study, unintended reproductive effects are noted in male sheep (ram) and pigs (also known as porcine or swine). This research focuses on the impact of ipconazole exposure on spermatozoa (sperm) in two mammal species and finds spermiotoxicity through significantly reduced sperm viability, as well as alterations in enzyme and gene expression related to fertility.  “To our knowledge, this is the first study to evaluate the cytotoxic effect of the triazole ipconazole on mammalian spermatozoa,” the authors share. This analysis utilizes semen samples from the Reproductive Biotechnology Laboratory of the Major National University of San Marcos in Lima, Peru, the university where six of the nine researchers are Faculty of Veterinary Medicine.   “The sperm were exposed to ipconazole concentrations of 1, 5, 10, 50 and 100 ÂľM, and to a control without ipconazole,” they say. Similar concentrations have been used in previous cytotoxicity studies with ipconazole. […]

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07
Mar

On International Women’s Day, Pesticide Risks to Women’s Health Call for Urgent Transition to Organic

(Beyond Pesticides, March 7, 2025) In honor of International Women’s Day on Saturday, March 8, 2025, Beyond Pesticides sheds light on the disproportionate risks to women from toxic chemicals that are often unaccounted for and even dismissed throughout pesticide regulatory review and the underlying statutes. In a roundup of Daily News coverage in 2024, as well as the most recent scientific studies in 2025, on the scientific links between pesticide exposure and adverse effects in women, this article highlights the growing inequities in pesticide threats to women’s health.  Women farmers and farmworkers are particularly excluded when assessing pesticide risks. As previously reported by Beyond Pesticides, a study published in Occupational and Environmental Medicine finds that pesticide exposure, especially during puberty, can play a role in ovarian cancer development among female farmers. Although there are many studies that evaluate the risk for cancers among farmers, very few scientific articles cover the risk of ovarian cancer from pesticide exposure.  Additionally, this study suggests the role of hormones in ovarian cancer prognosis and development, highlighting an association with endocrine disruption. Endocrine disruption can lead to numerous health problems in multiple organ systems, including hormone-related cancer development (e.g., thyroid, breast, ovarian, prostate, testicular), reproductive […]

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20
Feb

Exposure to Glyphosate Herbicide Adversely Affects Perinatal Health, Study Finds

(Beyond Pesticides, February 20, 2025) Researchers at the University of Oregon found that the rollout of genetically engineered corn in the early 2000s, followed by exponential increases in glyphosate-based herbicides, “caused previously undocumented and unequal health costs for rural U.S. communities over the last 20 years.” Their results “suggest the introduction of GM [genetically modified] seeds and glyphosate significantly reduced average birthweight and gestational length.” The conclusions of this study emerge as fossil fuel advocates, including President Donald Trump, are mobilizing to pioneer “energy dominance” despite the market movement toward renewable energy. Just as chemical-intensive farmers and land managers continue to spray synthetic fertilizers and pesticides, a successful rollout of alternatives must rely on feeding the soil rather than the plant. Advocates continue to demand that elected officials and regulators embody the precautionary principle and scientific integrity in decision-making. Given the hostile federal climate on anything relating to holistic solutions, communities are coming together to move beyond input-dependent land management systems and adopt organic criteria of allowed and prohibited substances, mandatory public comment process, independent third-party certification, and a federal advisory board (National Organic Standards Board) consisting of farmers, environmentalists, consumers, scientists, economists, researchers, and other stakeholders, with binding recommendations […]

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11
Feb

Study Finds Increased Offspring Mortality in Pesticide-Laden Bird’s Nests

(Beyond Pesticides, February 11, 2025) In a Science of The Total Environment study, scientists test over 100 blue tit (Cyanistes caeruleus) and great tit (Parus major) birds’ nests for pesticide residues in comparison with the number of dead offspring and unhatched eggs within the nest. Fur-lined nests, from animals treated with ectoparasitic chemicals, expose birds to compounds that can impact reproductive success. The authors found fipronil, a phenyl pyrazole insecticide, in all nests, with the majority also containing the neonicotinoid insecticide imidacloprid and synthetic pyrethroid insecticide permethrin. The data shows higher insecticide levels are linked to increased offspring mortality and threaten biodiversity. This study highlights an important exposure route that is overlooked. “Although not all bird species use fur for nest building, a substantial number do, especially cavity-nesting species,” the researchers share. “Previous research found that 74% of studied woodland bird species in central Europe incorporated fur into their nests.” Many bird species in the U.S. also line their nests with fur, such as black-capped chickadees, tufted titmice, and chipping sparrows. While there is a wide body of science showing reproductive effects from pesticides, the researchers highlight the study’s novel design, saying, “To the best of our knowledge, no previous […]

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30
Jan

Study Finds Pesticide Exposure to Bees During Dormancy or Overwintering Disruptive of Reproductive Health

(Beyond Pesticides, January 30, 2025) A research article in Biology Letters, published by The Royal Society, finds that the neonicotinoid insecticide imidacloprid disrupts survival and reproductive patterns in Bombus impatiens bumblebees. The study adds to the wide body of science highlighting how exposure to pesticides “can result in immediate mortality or cause long-term detrimental effects on pollinators‘ health, lifespan and reproductive success,” the authors state. The researchers performed two experiments to assess the effects of various concentrations of imidacloprid, one of which focuses on bees during diapause, a period of dormancy. “Wild bees, which provide the majority of pollination services worldwide, undergo an annual life cycle that includes a winter diapause, that can span over 75% of their life cycle and during which their metabolism, growth and development are halted,” the authors note. They continue: “The time spent in diapause can have lasting effects on pollinator fitness and their ability to establish nests or colonies in the following spring. This period is especially critical for social bee colonies, which are founded by a single queen after diapause and play a vital role in large-scale pollination.” Exposure to pesticides during diapause can occur while bee species overwinter in contaminated soils. In […]

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09
Jan

Multiple Studies Link Adverse Effects on Female Reproductive Health with Endocrine Disrupting Chemical Exposure

(Beyond Pesticides, January 9, 2025) In a Frontiers in Public Health review article, researchers report on the wide body of science connecting adverse effects to female reproductive system, such as infertility, with exposure to endocrine-disrupting chemicals (EDCs). The authors call these effects a significant concern for public health, as there has been growing evidence of EDCs with risk factors for decreased fertility.   Infertility “affects a substantial proportion of the world’s population with approximately one in six people affected,” the researchers note. They continue: “Over the last 70 years, global fertility has been constantly in decline due to behavioral and societal changes… [E]merging evidence has shown that infertility incidence is linked to exposure to environmental factors such as tobacco, alcohol, and a wide range of endocrine-disrupting chemicals (EDCs) including pesticides (chlorpyrifos, glyphosate, dichlorodiphenyltrichloroethane [DDT] and methoxychlor), phthalates, polychlorinated biphenyls (PCB), dioxins, and bisphenols.”  In this review, over 100 studies are summarized to showcase the link between EDC exposure and reproductive effects in women, including infertility and related diseases such as endometriosis, premature ovarian insufficiency (POI), and endocrine axis dysregulation. The studies included investigating the “mechanisms by which EDCs cause ovarian aging, folliculogenesis, decrease of oocyte quality, ovulation disorders, development and receptivity […]

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13
Nov

Glyphosate Mixtures Show Lethal and Sublethal Effects to Embryos, Highlights Regulatory Deficiencies

(Beyond Pesticides, November 13, 2024) A study in Chemosphere, conducted by researchers from the Institute of Biochemistry and Molecular Biology in Germany, reveals the varied lethal and sublethal effects of different glyphosate mixtures through tests on the South African clawed frog, Xenopus laevis (X. laevis). After exposing embryos to four glyphosate formulations, mortality, morphological defects, altered heartbeat rate, and impaired heart-specific gene expression are observed. Glyphosate, an herbicide and popular weed killer in many RoundupÂŽ products, is one of the most commonly detected pesticides in waterbodies worldwide, threatening aquatic organisms and overall biodiversity. This study investigates the effects of Glyphosat TF, Durano TF, Helosate 450 TF, and Kyleo, four formulations containing glyphosate, as compared to the effects of pure glyphosate on embryonic development in amphibians. The formulations consist of varying concentrations of the active ingredient glyphosate, as well as other active and inert ingredients. The authors share that, “Glyphosat TF contains 34% glyphosate and 10–20% d-glucopyranose, while Durano contains 39–44% glyphosate and 1–5% N–N-dimethyl-C12-C14-(even numbered)-alkyl-1-amines. In Helosate most of the ingredients are listed – 50–70% glyphosate, 1–10% isopropylamine, 1–3% lauryl dimethyl betaine, 0.25–1% dodecyl dimethylamine. Kyleo only lists the active ingredients glyphosate (27.9%) and 2,4-D (32%).” 2-cell stage embryos (early […]

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05
Nov

Evaluation of EPA Safety Data on Neonicotinoid Insecticides Identifies Scientific Failures

(Beyond Pesticides, November 5, 2024) Published in the journal Frontiers in Toxicology, a recent study uncovers serious flaws in the pesticide registration process at the U.S. Environmental Protection Agency (EPA) with an in-depth evaluation of the agency’s failure to protect the public from the harmful effects of five neonicotinoid (neonic) insecticides—as mandated by the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and amendments, including Food Quality Protection Act (FQPA) of 1996. This coincides with EPA’s ongoing review to renew their approval for the next 15 years (set to be announced in 2025). The report is based on the first comprehensive assessment of unpublished rodent-based Developmental Neurotoxicity (DNT) studies, conducted between 2000-2003 and submitted by pesticide manufacturers as part of the registration process. All five neonicotinoids evaluated—acetamiprid, clothianidin, imidacloprid, thiacloprid, and thiamethoxam—are associated with significant shrinkage of brain tissue at the highest dosage, according to EPA data reports (see acetamiprid, clothianidin, imidacloprid, thiacloprid, and thiamethoxam). However, with little or no data regarding the chemicals’ impacts at low and mid-level dosages, EPA has either failed to find a “No Observed Adverse Effect Level” (NOAEL) or, seemingly at random, set the NOAEL at the mid-level dosage. The evaluation suggests that perinatal exposure to […]

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17
Oct

PFAS Contaminated Plastic Containers Focus of EPA Public Comment Period through November 29

Beyond Pesticides (October 17, 2024) On September 30, 2024, the U.S. Environmental Protection Agency (EPA) opened a public comment period about production of specific per- and polyfluoroalkyl substances (PFAS, also known as ‘forever chemicals’)—including perfluorooctanoic acid (PFOA), perfluorononanoic acid (PFNA), and perfluorodecanoic acid (PFDA). EPA is collecting information on the fluorination process of high-density polyethylene (HDPE) and other plastic containers to inform possible regulatory action under the Toxic Substances Control Act (TSCA). The deadline for submitting comments is November 29, 2024. PFOA and twelve other PFAS compounds are created during the fluorination of HDPE plastic containers by Inhance Technologies, LLC, the only U.S. company manufacturing containers using this fluorination technique (see here). Studies by EPA, independent researchers, and the company itself demonstrate that PFAS leaches from container walls into contents, exposing millions to these toxic chemicals without their knowledge. EPA notes, “Long-chain PFAS like PFOA, PFNA, and PFDA build up in our bodies and the environment over time. Even small amounts can significantly contribute to people’s long-term exposure and health risk for cancers, impacts to the liver and heart, and immune and developmental damage to infants and children.” The adverse effects of PFAS exposure are linked to serious health issues, […]

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