Archive for the '2,4-D' Category
19
Nov
(Beyond Pesticides, November 19, 2024) Researchers at Stanford University recently published a study in Cancer, an international interdisciplinary journal of the American Cancer Society (ACS), that reveals a correlation for numerous pesticides with increased prostate cancer occurrence and associated death. The study finds that exposure to 22 pesticides is positively associated with prostate cancer. The 22 pesticides include 2,4â€D, acephate, azoxystrobin, bifenthrin, carbaryl, chloropicrin, cloransulamâ€methyl, cyhalothrinâ€lambda, diflufenzopyr, diuron, glyphosate, hexazinone, linuron, methyl parathion, pendimethalin, propiconazole, sulfosate, thiamethoxam, thifensulfuron, tribenuron methyl, trifloxystrobin, and trifluralin. (See more on 2,4-D and cancer prevalence here and here.) As prostate cancer is a leading national health concern, the authors investigate agricultural pesticide exposure and compared it to prostate cancer incidence and mortality across counties in the contiguous U.S. “The geographic variation in prostate cancer incidence and mortality suggests that regional environmental factors, such as pesticide exposure, may contribute to the development of prostate cancer,” the researchers postulate. In comparing countyâ€level associations of 295 pesticides and prostate cancer reports, the authors were able to conduct an environmentâ€wide association study (EWAS) to determine any statistically significant links. “We acquired annual estimated total usage data (kg per county) for all pesticides reported and applied to agricultural crops grown […]
Posted in 2,4-D, Acephate, Azoxystrobin, Bifenthrin, Cancer, Carbaryl, chloropicrin, Death, Diuron, Glyphosate, hexazinone, Linuron, men's health, Parathion, Pendimethalin, Propiconazole, Prostate Cancer, Thiamethoxam, trifloxystrobin, Trifluralin | No Comments »
13
Nov
(Beyond Pesticides, November 13, 2024) A study in Chemosphere, conducted by researchers from the Institute of Biochemistry and Molecular Biology in Germany, reveals the varied lethal and sublethal effects of different glyphosate mixtures through tests on the South African clawed frog, Xenopus laevis (X. laevis). After exposing embryos to four glyphosate formulations, mortality, morphological defects, altered heartbeat rate, and impaired heart-specific gene expression are observed. Glyphosate, an herbicide and popular weed killer in many Roundup® products, is one of the most commonly detected pesticides in waterbodies worldwide, threatening aquatic organisms and overall biodiversity. This study investigates the effects of Glyphosat TF, Durano TF, Helosate 450 TF, and Kyleo, four formulations containing glyphosate, as compared to the effects of pure glyphosate on embryonic development in amphibians. The formulations consist of varying concentrations of the active ingredient glyphosate, as well as other active and inert ingredients. The authors share that, “Glyphosat TF contains 34% glyphosate and 10–20% d-glucopyranose, while Durano contains 39–44% glyphosate and 1–5% N–N-dimethyl-C12-C14-(even numbered)-alkyl-1-amines. In Helosate most of the ingredients are listed – 50–70% glyphosate, 1–10% isopropylamine, 1–3% lauryl dimethyl betaine, 0.25–1% dodecyl dimethylamine. Kyleo only lists the active ingredients glyphosate (27.9%) and 2,4-D (32%).” 2-cell stage embryos (early […]
Posted in 2,4-D, Aquatic Organisms, Biodiversity, Chemical Mixtures, Death, Developmental Disorders, DNA Damage, Endocrine Disruption, Environmental Protection Agency (EPA), Epigenetic, Glyphosate, Herbicides, Pesticide Mixtures, synergistic effects | No Comments »
21
Aug
(Beyond Pesticides, August 21, 2024) A literature review, published this month in the Journal of Agricultural and Food Chemistry, explores levels of pesticide residues found in samples of human urine with environmental exposure and dietary intake and confirms prior findings about the benefits of an organic diet. Similar to past findings, lower concentrations of chemicals are detected in the urine of participants who report eating an organic diet. By analyzing 72 scientific research studies published between 2001 to 2023, the review assesses routes of exposure and “explores urinary concentrations and detection frequency of metabolites of organophosphates and pyrethroids, as well as herbicides such as 2,4-D and glyphosate,” the authors say. While “exposure to pesticide residues is influenced by a variety of demographic factors, including occupation, agricultural practices, seasonal variations, residence, diet, age, and gender,” the authors say, the concentrations of pesticides and their metabolites in human urine highlights the disproportionate risk to certain groups as well as the overall threat to the health of humans and the environment. Pesticide exposure can occur from dermal/skin contact or inhalation, through residence or work, and with dietary intake. “Pesticides in urine can be detected as parent compounds, specific metabolites corresponding to a specific […]
Posted in 2,4-D, Alternatives/Organics, Chlorpyrifos, cypermethrin, Deltamethrin, Farmworkers, Glyphosate, Metabolites, Permethrin, Synthetic Pyrethroids | No Comments »
16
Jul
(Beyond Pesticides, July 16, 2024) Yet another study in the August 2024 journal Ecotoxicology and Environmental Safety has found that exposure to organophosphorus pesticides (OPPs) is correlated with increased suicidal thoughts in some people. This study is just the latest in a long line of studies from around the world that have linked pesticide exposure to mental health conditions, including sleep disorders, depression, and suicidal ideation (SI). As the rate of suicide increased by 30% between 2000 and 2020, there is an urgent public health need to investigate and address all potential contributing factors. A 2019 study, covered in Daily News, found that teens and adolescents living in agricultural areas and exposed to organophosphate (OP) insecticides are at higher risk of depression, In July and January this year, other studies link farmer psychiatric episodes to pesticide exposure, adding to the body of science. Exposure to household pesticides is also linked to depression in a 2020 study.  Study and Methodology The study entitled “Association between exposure to organophosphorus pesticide and suicidal ideation among U.S. adults: A population-based study,” analyzes information on the mental and physical health of over 5,000 individuals aged 20 and up in the United States. The study aims […]
Posted in 2,4-D, Agriculture, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention (CDC), Chemical Mixtures, Death, Depression, Disease/Health Effects, Farmworkers, Increased Vulnerability to Diseases from Chemical Exposure, men's health, Occupational Health, organophosphate, Pesticide Mixtures, Suicide, Uncategorized | No Comments »
04
Jun
(Beyond Pesticides, June 4, 2024) A study published in the most recent edition of the journal Ecotoxicology and Environmental Safety documents for the first time the presence of the herbicide glyphosate in human sperm. The study looked at 128 French men with an average age of 36 years who tested positive for glyphosate in their blood. Seventy-three out of the 128 men were found to also have glyphosate in their seminal plasma. Not only that, the amount of glyphosate in seminal plasma was nearly four times higher than what was detected in the blood.  Methods The study involved a population of 128 infertile French men from whom seminal and blood plasma samples were collected. The study was conducted at the “Pole SantĂ© LĂ©onard de Vinci” medical center, located centrally near Tours, France. This region is recognized for its urban characteristics as well as being a major agricultural hub, particularly for grain and wine production. The study authors note, “This area reflects the common herbicide exposure in France” and the district ranks third highest in terms of pesticide purchases. While additional qualitative data was collected, only 47 of 128 participants fully completed a questionnaire about their profession, diet (organic or […]
Posted in 2,4-D, aminomethylphosphonic acid (AMPA), Antibiotic, Bayer, behavioral and cognitive effects, Birth defects, Chemicals, Developmental Disorders, Dicamba, Disease/Health Effects, DNA Damage, Endocrine Disruption, Environmental Protection Agency (EPA), Genetic Engineering, Glyphosate, Groundwater, Gut Dysbiosis, Herbicides, Infertility, Inflammatory bowel disease (IBD), IQ Loss, Kidney failure, Lawns/Landscapes, Leukemia, Litigation, Liver Damage, Lymphoma, men's health, Miscarriage, Monsanto, non-Hodgkin's Lymphoma, Oxidative Stress, Pesticide Regulation, Pesticide Residues, PFAS, Reproductive Health, synergistic effects, Uncategorized, World Health Organization | No Comments »
21
May
(Beyond Pesticides, May 21, 2024) In a first-of-its kind series of biomonitoring studies published in Agrochemicals, researchers identified the presence of the herbicides dicamba and 2,4-D in all pregnant participants from both cohorts in 2010-2012 and 2020-2022. The findings from this research are not surprising given the explosion of toxic petrochemical pesticides in the Midwest region of the United States. “The overall level of dicamba use (kilograms applied in one hundred thousands) in the U.S. has increased for soybeans since 2015 and slightly increased for cotton and corn,” the authors report, based on U.S. Department of Agriculture National Agriculture Statistics Service surveys. “The overall level of 2,4-D use (kilograms applied in one hundred thousands) in the U.S. was highest in 2010 for wheat, soybeans, and corn. The amount of 2,4-D applied increased the most for soybeans and corn from 2010 to 2020.” The researchers focused on the states of Illinois, Indiana, and Ohio, given the increase in dicamba and 2,4-D during the study period for both cohorts (2010-2022). The researchers are based at Indiana University School of Medicine in the Department of Biostatistics and Health Data Science and Department of Obstetrics and Gynecology, Quebec Toxicology Center within the Institut national […]
Posted in 2,4-D, Dicamba, Environmental Protection Agency (EPA), Federal Agencies, Illinois, Indiana, Ohio, Uncategorized, US Department of Agriculture (USDA) | No Comments »
18
Apr
(Beyond Pesticides, April 18, 2024) University of Michigan researchers have found a statistically significant relationship between heightened risk of amyotrophic lateral sclerosis (ALS) and household exposure to lawn care products and pesticides. The study results were published earlier this month in Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. The interdisciplinary research team concludes that modifying residential exposure to toxic substances, including pesticides, can play an important role in ALS susceptibility and prognosis. The results build on a substantial body of scientific literature identifying pesticide exposure in various ALS cohort studies. Advocates say that these adverse effects, along with other numerous health and environmental effects, inform their call for the phaseout of toxic pesticide use and the adoption of alternative practices and eco-compatible products. All participants in this study are patients at the University of Michigan Pranger ALS Clinic with Gold Coast ALS diagnosis, which according to a Muscle & Nerve study refers to the identification of two factors: “progressive motor impairment documented by history or repeated clinical assessment” and “the presence of upper and lower motor neuron dysfunction in a least one body region.” All 367 ALS and 255 control patients were tasked with completing a survey in which they self-reported […]
Posted in 2,4-D, Amyotrophic Lateral Sclerosis (ALS), Biomonitoring, Carbaryl, Chlorpyrifos, Disease/Health Effects, Glyphosate, Herbicides, Lawns/Landscapes, Michigan, Pesticide Drift, Pesticide Residues, Poisoning, Uncategorized | No Comments »
10
Apr
(Beyond Pesticides, April 10, 2024) Researchers in a 2024 Chemosphere study find synergistic relationships in certain chemical mixtures, particularly heptachlor and triallate and trifluralin and lindane at lower concentrations, respectively. “Investigators should consider additional binary data for acute toxicity and potential chronic health impacts on these mixture…which showed synergism at low levels,” the researchers conclude. “According to a Centers for Disease Control (CDC) assessment, more than 50 pesticides are detected in blood or urine samples from the US population,” Researchers point to a cause for concern. The findings come as no surprise to advocates who have urged an assessment of the potential synergistic impacts of pesticide mixtures in the regulation of pesticides. Researchers “used the exposure data from a complex operating site with legacy pesticide pollution to evaluate if Inhalation of pesticide mixtures released from such contaminated sites could pose a risk to human health, The component-based risk assessment approaches that rely on additivity can predict the actual risk of pesticides in a mixture, and The legacy organochlorine pesticides banned many years ago interact with registered and supposedly safe herbicides in a mixture.” The study site is “a pesticide packaging and handling facility” contaminated with the following pesticides (“historical and […]
Posted in 2,4-D, Chemical Mixtures, contamination, Heptachlor, Lindane, Trifluralin, Uncategorized | No Comments »
21
Feb
(Beyond Pesticides, February 21, 2024) In addition to its effects including cancer, and reproductive, immune or nervous system disruption, according to international findings, a review published in Toxics finds that the the widely used weed killer 2,4-dichlorophenoxyacetic acid (2,4-D) causes significant changes in liver structure and function. 2,4-D can damage liver cells, tissue, and inflammatory responses through the induction of oxidative stress. The liver, the largest solid organ in the human body, is an essential part of the digestive system responsible for blood detoxification, nutrient metabolization, and immune function regulation. However, rates of chronic liver diseases are increasing, representing the second leading cause of mortality among all digestive diseases in the U.S. In fact, researchers warn of the rise in liver disorders and metabolic syndrome among young people. Therefore, reviews like this highlight the research available to make decisions on safeguarding human health from chemical exposure to mitigate further disease outcomes and complications. 2,4-D is used on turf, lawns, and rights-of-way, as well as in forestry and aquatic systems. 2,4-D products are available as liquid, dust, and granule fields, as well as fruit and vegetable crops, including in genetically engineered crop production. The chemical is widely used in “weed and feed” lawn products. It is […]
Posted in 2,4-D, Agriculture, Environmental Protection Agency (EPA), Lawns/Landscapes, Liver Damage, Oxidative Stress | 3 Comments »
24
Jan
(Beyond Pesticides, January 24, 2024) A study published in Environmental Sciences Europe finds that 2,4-D, pyrethroid (PRY), and organophosphate (OP) pesticides increase the risk of cancer through oxidative stress (OS). The study highlights that pesticides that increase cancer risk also raise inflammation biomarkers that indicate damage to organs (e.g., liver) via oxidative stress. Additionally, different cancers show different sensitivities to pesticides; thus, cancer risk changes with exposure concentration and pattern. Despite a plethora of studies linking cancer and pesticide exposure, very few cover the mechanisms involved in cancer development, including OS. Only five to ten percent of cancers are hereditary. However, environmental or lifestyle factors, like chemical exposure, can make an individual more susceptible to cancer development through gene mutation. In fact, a vast amalgamation of research links cancer risk to pesticide exposure, which augments the risk of developing both common and rare cancers. Therefore, studies like this highlight the importance of understanding how pesticide use can increase the risk of latent diseases, which do not readily develop upon initial exposure. Using data from the National Health and Nutrition Examination Survey (NHANES), researchers investigated the link between the risk of several cancers and pesticide exposure. The researchers also thoroughly evaluated […]
Posted in 2,4-D, Cancer, Liver Damage, organophosphate, Oxidative Stress, pyrethroids, Synthetic Pyrethroid, Uncategorized | 1 Comment »
19
Jan
(Beyond Pesticides, January 19, 2024) A study published in Environmental Health Perspective is one of the first to indicate a link between exposure to the herbicides 2,4-D and glyphosate and the impairment of behavioral performance (i.e., attention/inhibitory control, memory/learning, language, visuospatial processing, and social perception). These adverse effects associated with the neurotoxic impacts of pesticides on behavior have been previously documented. For example, a study in August 2023 finds oral intake (e.g., eating contaminated foods), inhalation, and dermal exposure to glyphosate lowered cognitive function scores, increased the likelihood of severe depressive symptoms, and impaired auditory (hearing) function. Although previous studies find neurotoxic effects from exposure to these herbicides, very few until now have evaluated how this neurotoxic exposure impacts neurotypical behavior among youth (children and teenagers). The ubiquitous use of glyphosate and 2,4-D use in agriculture—which leaves residues of the toxic chemicals in food and in public areas (e.g., parks and walkways) creates a creates a significant risk for exposure. Glyphosate is already implicated in or proven to lead to the development of numerous health anomalies, including cancer, while 2,4-D also has a range of potential hazards, including cancer. Therefore, studies like this help local and government officials make holistic decisions regarding the use […]
Posted in 2,4-D, behavioral and cognitive effects, Brain Effects, Children, DEET, Glyphosate, Herbicides, synergistic effects | No Comments »
08
Nov
(Beyond Pesticides, November 8, 2022) Glyphosate weed killers induce antibiotic resistance in deadly hospital-acquired bacteria, according to a new study published late last month in the journal Scientific Reports. This is the latest finding connecting commonly used herbicides to the rise of antibiotic resistant bacteria, with prior research showing glyphosate, 2,4-D, and dicamba able to create resistance in Salmonella and E. coli. While federal regulatory agencies continue ignore the role of pesticides in the development of antibiotic resistance, it is critical for states and localities to take action to protect their most vulnerable both from toxic exposure to these herbicides and the multitude of indirect effects caused by their use. This is all happening as antibiotic resistance is rising to dangerously high levels in all parts of the world, according to the World Health Organization. In the May 1, 2022 issues of the Bulletin of the World Health Organization, Samira Choudhury, PhD, et al. writes, “Often referred to as the silent pandemic, antimicrobial resistance claims the lives of over 700,000 people annually.” The authors continue, “A study suggests that if no actions are taken, antimicrobial resistance will cause 10 million deaths per year by 2050 and an economic impact of […]
Posted in 2,4-D, Agriculture, Antibiotic, Dicamba, Environmental Protection Agency (EPA), Glyphosate, Infectious Disease, Uncategorized | No Comments »
10
May
(Beyond Pesticides, May 10, 2022) Widespread weed resistance on chemical corn and soybean farms is leading farmers to till their fields more often, significantly increasing greenhouse gas (GHG) emissions. These findings were published late last month in the journal Nature Food by a team of Iowa State University researchers. With agricultural practices accounting for roughly 10% of U.S. GHG emissions, and 25% of worldwide releases, farming practices that preserve soil health and sequester GHGs are essential for the future of food production. Tillage is a farming practice that can provide a range of benefits for crop production, but only in the right conditions. A range of tillage practices exist, ranging from yearly conventional tillage, where most crop residue is plowed into the soil, to conservation tillage where some residue remains, and no-till systems where the soil remains covered. Repeated tillage causes significant harm to soil structure and biology, and result in erosion and the release of GHGs like carbon dioxide, methane, and nitrous oxide from soil into the atmosphere. The harms of tillage have led both chemical and organic farmers toward no-till or reduced tillage systems. Organic no-till farming, as practiced by farming groups like the Rodale Institute, employs the […]
Posted in 2,4-D, Alternatives/Organics, Dicamba, Genetic Engineering, glufosinate, Glyphosate, Resistance, Uncategorized | No Comments »
05
Apr
(Beyond Pesticides, April 5, 2022) A meta-analysis by the Federal University of Technology – Paraná finds the herbicide 2,4-D causes indiscriminate harm, increasing the mortality rate among exposed animals. The severity of chemical exposure relies on species sensitivity, exposure rate, and lifecycle stage. However, commercial formulations of 2,4-D, commonly used in the environment, prompt a higher species mortality rate than technical (pure) 2,4-D alone. Like many other common herbicides such as glyphosate, 2,4-D has global uses that allow the chemical to accumulate in the environment, including soils, waterways, and tissues of non-target species. Therefore, meta-analyses like this help local and government officials make holistic decisions regarding environmental contaminants that incorporate conclusions from various studies. Using the Web of Science and Scopus databases, researchers compiled various studies (or meta-analyses) on the lethality of 2,4-D in different animal species (e.g., vertebrates, invertebrates). Researchers evaluated each study regarding the mortality rate of control and experimental groups, animal sensitivity to chemical exposure during a specific life stage, chemical formulation (e.g., commercial or technical), and exposure routes causing mortality. The analysis demonstrates that vertebrates experience higher mortality rates from 2,4-D exposure, with fish and birds presenting the highest mortality rate. Regarding life stages, larval and adult […]
Posted in 2,4-D, Wildlife/Endangered Sp. | 1 Comment »
09
Mar
(Beyond Pesticides, March 9, 2022) In response to local concerns around children’s environmental exposures, the Minnesota Department of Health (MDH) recently published biomonitoring data collected from young children living in urban and rural areas of the state. The findings provide local residents and lawmakers with baseline data on the hazards children are encountering where they live, learn, or play, and point to ways in which families can reduce or eliminate these dangers. With evidence that early life exposures during “critical windows of vulnerability” increase risk of long-term health problems, it is critical for state agencies to both collect data, and take meaningful action to protect children from future harms. Minnesota lawmakers established a state biomonitoring program in 2007, and have since expanded the project. The current report represents the results of MDH’s Healthy Rural and Urban Kids Project aimed at biomonitoring chemicals in young children. For this round, the agency focused on preschool-aged children living in MN’s rural Becker, Todd, and Wadena counties, as well as those living in urban North Minneapolis. MDH enrolled 232 families during the summer of 2018, provided them with a questionnaire, and tested children for 21 different chemicals in their urine. The chemicals tested were […]
Posted in 2,4-D, Agriculture, Children, Household Use, Lawns/Landscapes, Minnesota, Uncategorized | No Comments »
03
Mar
(Beyond Pesticides, March 3, 2022) Children’s exposure to synthetic pyrethroid insecticides, particularly during the course of mosquito control operations, is associated with increased occurrence of certain respiratory diseases and allergic outcomes, finds research published in the journal Thorax late last month. With a pandemic respiratory virus continuing to spread throughout the world, it has become increasingly important to avoid environmental exposures that can harm lung health. This research underscores the critical need for homeowners, farmers, and vector control officials to shift away from chemical use as the first line of defense against pest problems in order to safeguard children’s health. A total of 303 women and their children participated in the study, which tracked pesticide exposure during pregnancy and then at age five. All participants in the study lived within roughly three miles of a banana plantation. A structured questionnaire captured a range of variables, from socioeconomic status to medical history, local environmental conditions, occupation, and demographics. Researchers collected urine samples from pregnant mothers during the first visit, and their children during the 5-year follow-up. Urine samples were analyzed for metabolites concerning a range of pesticides, including chlorpyrifos, synthetic pyrethroids, the fungicides mancozeb, pyrimethanil, and thiabendazole, and the herbicide 2,4-D. […]
Posted in 2,4-D, Chlorpyrifos, mancozeb, Mosquitoes, pyrimethanil, Synthetic Pyrethroid, thiabendazole, Uncategorized | No Comments »
01
Mar
(Beyond Pesticides, March 1, 2022) A report by the Independent finds chemical-intensive farming of crops for animal feed puts thousands of endangered species at risk. U.S. farmlands use more than 235 million pounds of pesticide (i.e., herbicides and insecticides) solely for animal feed production, many of which are highly hazardous pesticides (HHPs). Several HHP hazard categories include acutely toxic, chronic health hazards, and environmental hazards. Therefore, animal feed production intensifies global pollution, increases pesticide exposure, and degrades human, animal, and ecological health. Although the report demonstrates a need to eliminate toxic pesticide use for the sake of human, animal, and ecosystem health, it will take more than eliminating the worst chemicals to address the impending biodiversity collapse and the climate crisis. Experts highlight the need for an urgent shift to organic land and agricultural management practices. The study notes, “These pesticides are taking a toll on our environment and biodiversity. Endangered species like the highly imperiled whooping crane, monarch butterflies, all species of salmon, the rusty-patched bumble bee, the San Joaquin kit fox, and the northern long-eared bat, as examples, all face significant threats from industrial agricultural operations and the chemicals applied. In order to conserve biodiversity and better protect vulnerable species and their habitats, […]
Posted in 2,4-D, Agriculture, Atrazine, Bifenthrin, Dicamba, Glyphosate, neonicotinoids, Paraquat, Wildlife/Endangered Sp. | No Comments »
15
Feb
(Beyond Pesticides, February 15, 2022) A synthetic weed killer linked to cancer, endocrine (hormone) disruption, reproductive harm and birth defects can be found in the bodies of 1 in 3 Americans, according to research published in Environmental Health by scientists at George Washington University. The chemical in question is not glyphosate (though current data indicate similar results are likely) but 2,4-D, an herbicide that is increasingly used when weeds growing near genetically engineered  (GE) crops have developed resistance to the repeated use of Roundup and other glyphosate-based weed killers. “Our study suggests human exposures to 2,4-D have gone up significantly and they are predicted to rise even more in the future,” Marlaina Freisthler, a PhD student and researcher at the George Washington University, said. “These findings raise concerns with regard to whether this heavily used weed-killer might cause health problems, especially for young children who are very sensitive to chemical exposures.” Researchers conducted their analysis based on data from the National Health and Nutrition Examination Survey, which includes urinary concentrations of 2,4-D from 14,395 participants spanning 2001 to 2014. Between those years, the use of 2,4-D increased rapidly from its relative low point at the beginning of the century. “Roundup […]
Posted in 2,4-D, Agriculture, Cancer, Glyphosate, non-Hodgkin's Lymphoma, Uncategorized, US Department of Agriculture (USDA) | No Comments »
19
Oct
(Beyond Pesticides, October 19, 2021) Exposure to the insecticide malathion increases risk of developing chronic kidney disease (CKD), according to a study recently published in the International Journal of Environmental Research and Public Health. According to study co-author Nicholas Osborne, PhD, CKD is on the rise in developing countries in Southeast Asia and Central America, and, “[n]early one in 10 people in high income countries show signs of CKD, which is permanent kidney damage and loss of renal function.” Although CKD risk increases with age, and is associated with other health factors like smoking, heart disease, and diabetes, cases without clear cause are increasingly common, indicating the that environmental factors are likely playing a role. Researchers began with data drawn from the United States’ National Health and Nutrition Examination Survey (NHANES), an ongoing study that assesses Americans’ health and nutritional status through interviews, physicals, and other health tests. Urine samples taken from individuals enrolled in NHANES 2001-2004 and 2007-2010 (tests within years between these dates did not analyze specific pesticides) were reviewed for the presence of pesticides, and compared against data collected on kidney function. In addition to malathion, 2,4-D, chlorpyrifos, and 3-PBA, the major metabolite for most synthetic pyrethroid insecticides, […]
Posted in 2,4-D, Agriculture, Chlorpyrifos, Environmental Protection Agency (EPA), Kidney failure, Malathion, Synthetic Pyrethroid, Uncategorized | No Comments »
30
Sep
(Beyond Pesticides, September 30, 2021) Individuals working or living in areas with frequent neurotoxic pesticide use experience more amyotrophic lateral sclerosis (ALS) incidences than the general population. The study, published in NeuroToxicology, finds a positive association between sporadic (non-genetic, spontaneous) ALS incidences among individuals exposed to neurotoxic pesticides. Amyotrophic lateral sclerosis (or Lou Gehrig’s disease) is a neurodegenerative disease that affects the nerves in the brain and spinal cord. As many as 16,000 – 20,000 Americans live with this condition, which weakens muscle/motor function leading to loss of muscle control for walking, talking, eating/swallowing, and breathing. Severe ALS progression is fatal and has no current cure. Although research supports genetic factors play a role in disease etiology (cause), most ALS cases do not result from genetic inheritance. Several research studies demonstrate exposure to environmental or work-related toxicants (i.e., pesticides) predispose humans to the disease. With researchers predicting a global ALS incidence increase of 69% by 2040, identifying ALS’s causal factors are important to future research. Therefore, research like this showcases the importance of assessing aggregate health risks associated with toxic chemical exposure, especially for illnesses, which are not curable. In this study, the researchers note, “[W]e identified pesticides applied to crops in the area of […]
Posted in 2,4-D, Agriculture, Amyotrophic Lateral Sclerosis (ALS), Carbaryl, Chlorpyrifos, Glyphosate, Herbicides, Nervous System Effects | 1 Comment »
10
Sep
(Beyond Pesticides, September 10, 2021) Research conducted in Thailand shows that exposures to pesticides, even at low levels, can impact the human endocrine system and distort thyroid function. The study looked specifically at interactions of genetics and environment: it investigated associations between variations in genes involved in pesticide metabolism and altered thyroid hormone concentrations in agricultural workers. This research underscores some of the complexity and difficulty of determining human vulnerability to impacts of pesticide exposures, given genetic variables. Beyond Pesticides believes that this very complexity is a cogent argument for anchoring regulation of pesticides in the Precautionary Principle. If exposure to a pesticide can cause damage to human (or environmental) health, it sometimes will do so. Thus, to protect people’s health, agriculture and other land management practices must transition from the use of synthetic pesticides to broad adoption of organic regenerative approaches that obviate the need for such chemicals. This research is part of a longitudinal study that seeks to evaluate sub-chronic impacts, on thyroid hormone levels, of repeated exposures to a variety of pesticides. The farmworkers studied in this phase comprise two groups: those working on organically managed farms (216 subjects), and those working on conventional farms that use pesticides […]
Posted in 2,4-D, Agriculture, Carbaryl, Chlorpyrifos, cypermethrin, Endocrine Disruption, Environmental Protection Agency (EPA), Glyphosate, Lindane, Thyroid Disease, Uncategorized | No Comments »
01
Oct
(Beyond Pesticides, October 1, 2020) A federal judge on September 24, 2020 dismissed an  environmental lawsuit seeking to reinstate a U.S. Fish and Wildlife Service (FWS) rule, killed by the Trump Administration, which banned the use of neonicotinoid insecticides, genetically engineered (GE) crops, and adopted a precautionary approach to pest management. The decision comes on the heels of a Center for Biological Diversity (CBD) analysis that reports a 34% increase in the pesticide use on U.S. national wildlife refuge acres over a two year period from 2016-2018. This analysis is an update to CBD’s 2018 report, No Refuge, which is the first of its kind to offer comprehensive details of agricultural pesticide spraying in national wildlife refuges. Wildlife refuges act as a sanctuary, providing habitat and protection essential for the survival and recovery of species nationwide. However, pesticide spraying in or around wildlife refuges threatens the survivability and recovery of species that reside there as many of these pesticides are highly toxic to human and animal health. Analyses like these are significant, especially since the globe is currently going through the Holocene Extinction, Earth’s 6th mass extinction, with one million species of plants and animals at risk of extinction. In 2012, […]
Posted in 2,4-D, Agriculture, Alternatives/Organics, Biodiversity, contamination, Dicamba, Federal Agencies, Fish and Wildlife Service (FWS), Genetic Engineering, Paraquat, Wildlife/Endangered Sp. | No Comments »
11
Aug
(Beyond Pesticides, August 11, 2020) Petitioners who mounted a legal challenge to the Environmental Protection Agency’s (EPA’s) registration of Enlist Duo, a relatively new and highly toxic pesticide product, recently learned of a mixed decision from the U.S. Ninth Circuit Court of Appeals in the case. The good news is that Judge Ryan D. Nelson, writing the opinion for the court, found that EPA, in registering the herbicide Enlist Duo, had failed to protect monarch butterflies, which are under consideration as a threatened species under the Endangered Species Act (ESA). On the other and disturbing hand, the court concluded that EPA registration of the product was otherwise lawful — which means that this toxic compound will for now remain on the market. As one of the plaintiffs in the case, Beyond Pesticides is adamant that this product should not be registered for use by EPA. George Kimbrell, Legal Director of Center for Food Safety and Lead Counsel for the plaintiffs, commented on the decision in the organization’s July 22 press release on the decision: “The panel majority’s unprecedented decision is contrary to controlling law and established science, and Center for Food Safety is analyzing all legal options, including seeking a full […]
Posted in 2,4-D, Bayer, Dow Chemical, Environmental Protection Agency (EPA), Glyphosate, Monsanto, Uncategorized | No Comments »