(Beyond Pesticides, December 24, 2024 – January 2, 2025) We wish you a healthy and happy holiday season! The health and environmental challenges that we face as families and communities across the nation and worldwide require us to stay engaged. The stark reality of the challenges ahead energizes us at Beyond Pesticides to strengthen our program—now, more than ever!   And, we trust that you, like us, want to push forward for a livable future. In this context, please see our annual report and summary on the important work that we are doing, and please consider a contribution to Beyond Pesticides during this holiday season.  While the threats of health, biodiversity, and climate crises grow exponentially, the solutions we have advocated for decades are now within reach. We know how to produce food and manage land without petrochemical pesticides and fertilizers, as organic food is widely available. Beautiful parks, playing fields, and schoolyards do not require toxic chemical use. At the same time, the regulatory system underperforms, as existential health and environmental problems escalate.   And, we know that individual steps that we take to stay healthy, as important as they are, cannot protect us and the natural world, on which […]

(Beyond Pesticides, December 19, 2024) As The New York Times reported last month, the government in South Africa declared a national emergency—23 children died and nearly 900 people were sickened from pesticide poisoning in Johannesburg’s Soweto township. The illnesses and fatalities have been traced to small amounts of highly neurotoxic pesticides, including the insecticides terbufos and aldicarb, found in local food items. These chemicals, described by South African President Cyril Ramaphosa as “street pesticides,” are being increasingly used (legally and illegally) for pest infestations in the townships and informal settlements of South Africa’s poorest communities, where poverty and inadequate waste collection exacerbates the pest management challenges. Without formal electricity, running water, or municipal garbage collection, many residents rely on highly toxic pesticides for pest infestations in their homes and makeshift markets, resulting in food inadvertently being contaminated with pesticides.  The announcement highlights the dangers of allowing these highly toxic agricultural chemicals to be used in farming, with tragic consequences for vulnerable communities when they are diverted for use in urban settings. This tragic situation also draws attention to the elevated threat that pesticides pose when stringent enforcement mechanisms are not in place to ensure compliance with pesticide restrictions, even with […]

(Beyond Pesticides, December 12, 2024) A literature review of 161 articles in Discover Toxicology finds that pesticides with different mechanisms of action cause memory and learning impairments. These effects are noted in nontarget species including humans. Pesticide “[e]xposure during development, as well as chronic environmental and occupational exposure, can contribute to decreased cognitive performance,” the researchers say. With a focus on organophosphate pesticides, synthetic pyrethroids, and neonicotinoid insecticides, the authors highlight neurological impacts. Both learning and memory are crucial for the survival of many species. “Considering the importance of learning and memory for human and non-human animal behavior and the growing association between pesticide exposure and cognitive impairment, the aim of this review was to describe the studies showing the impact of pesticide exposure on memory and learning abilities in nontarget species, providing evidence of the impact of pesticides in central nervous system function,” the researchers state. The 161 articles included in the review were identified through database searches in PubMed/Medline and Scielo. The authors note, “Inclusion criteria for article selection included all articles published in English between 2015 and 2024 containing original studies in animals or humans with single or multiple pesticides exposure.” The articles consist of 132 preclinical […]

(Beyond Pesticides, November 7, 2024) Organic banana production is significantly more conducive to microbial decomposition than its chemical-intensive counterparts in the Caribbean nation of Martinique, according to a recent study published in Applied Soil Ecology. “Macrofaunal decomposition was increased more (55%) than microbial decomposition (20%), indicating that organic farming removes a constraint of conventional farming especially affecting macrofauna.” Biological activity in the soil is foundational to organic land management and critical to the cycling of nutrients that feed plant life while contributing to resiliency and soil water retention. Bananas are one of the most highly consumed fresh fruits in the U.S. marketplace. A consumer survey conducted by the International Fresh Produce Association in 2023 identified 84% of households purchasing bananas that year. The U.S. Department of Agriculture (USDA) Economic Research Service identifies bananas as the third most consumed fruit product in the United States, with the average person eating 13.2 pounds that year. Since bananas require specific bioclimatic conditions for commercial production that meets ongoing consumer demand, the proliferation of industrial-scale monoculture banana plantations in various Central and South American countries and territories has and continues to devastate local and Indigenous communities for generations. Environmental justice and public health advocates […]

(Beyond Pesticides, November 6, 2024) An analysis in the International Journal of Research Publication and Reviews emphasizes the role of biodiversity in agriculture, adding to a wide body of science on its importance. The authors, from Western Illinois University in the United States and Rome Business School in Italy, find that biodiversity supports critical ecosystems and organisms needed for sustainable food production. Through literature reviews and case studies, the interconnectedness of agriculture with plant and animal diversity, beneficial insects, soil health, and climate change is highlighted, as well as the need to manage land organically to support biodiversity. Plant and Animal Diversity As the researchers note, “A diverse agricultural system can better absorb shocks and maintain productivity, ensuring food security in the face of uncertainty.” A wide range of species present within ecosystems protects from changing environmental conditions and improves resilience. When farmers use monocultures for their crops, this leads to reduced ecosystem services from beneficial insects and increased vulnerability to pests and diseases. “By contrast, diverse cropping systems can enhance resilience, providing a buffer against environmental changes and fostering sustainable food production,” the authors say. Research shows that higher plant diversity disrupts pest life cycles and promotes beneficial insects, […]

(Beyond Pesticides, October 15, 2024) In Environmental Epidemiology, researchers from Columbia University and the University of Southern California, along with representatives from the nonprofit Comite Civico del Valle in Brawley, California, report the heightened risk of wheezing for five- to twelve-year-olds in the rural communities of California’s Imperial Valley. Through a school-based survey, the authors find associations between living near pesticide applications and more wheeze symptoms among the children. According to the authors, residents of the Imperial Valley, which is located near the border between the United States (U.S.) and Mexico, “are primarily Latino, 1 in 3 children live in poverty, and there is a 20% unemployment rate. The county faces poor air quality and excess particulate matter levels. Further, one in five children is diagnosed with asthma and the rate of asthma-related pediatric emergency room visits and hospitalizations is two times the CA state average.” This highlights the disproportionate risk for residents in this area regarding environmental exposure to harmful chemicals. Children are already more susceptible to health complications following pesticide exposure, as they take in greater amounts of toxic chemicals relative to their body weight and have still-developing organ systems. Young children in environments with higher levels of […]

(Beyond Pesticides, October 2, 2024) A comprehensive literature review in Ecotoxicology and Environmental Safety links a heightened risk of spontaneous abortion (SAB) with pesticide exposure. “The strengths of our study include being the first systematic review and meta-analysis to explore the association between exposure to pesticides and the risk of SAB,” the authors say. This novel approach includes analyzing 18 studies, totaling 439,097 pregnant participants, that allows the researchers to highlight an important public health issue and raise concerns for maternal contact with the harmful chemicals in pesticide products. SAB, also known as spontaneous miscarriage, is defined as the loss of pregnancy occurring prior to 20 weeks of gestation. “It has been observed that approximately 10–15% of pregnancies end up terminating spontaneously,” the researchers report. According to the authors, these negative birth outcomes can be attributed to many factors such as advanced maternal age, anatomical, immunological, and endocrinological disorders, infections, tobacco use, alcohol intake, abnormalities of the placenta, and exposure to heavy metals, radiation, and pesticides. To connect SAB specifically to pesticide exposure in mothers, a literature search was conducted for peer-reviewed studies that include pregnant study participants, ages 16 and above, who report “exposure to one or more pesticides […]

(Beyond Pesticides, September 26, 2024) DNA damage is significantly higher in Latinx children from rural, farmworker families than children in urban, non-farmworker families, according to a recent study published by French and American authors in the journal Exposure and Health. Not only do farmworker children test positive for organophosphate pesticides more frequently than non-farmworker children, but the study finds that farmworker children also experience an increased frequency of DNA damage associated with the presence of organophosphate exposure. These results highlight the disparities in exposures and outcomes for children from vulnerable immigrant communities. Advocates note that as long as pesticides remain in use, farmworkers and their families will continue to shoulder a disproportionate share of the toxic effects of these chemicals (see here, here, and here); another in a long line of reasons to shift away from toxic synthetic pesticide use to the adoption of proven organic, regenerative agricultural practices. (See here, here, and here). Methodology The study assesses pesticide exposure and DNA damage in 45 Latinx children ages 10 to 12 from rural, farmworker families (30) and urban, non-farmworker families (15). Participants were selected from a larger study, Preventing Agricultural Chemical Exposure (PACE5)—a community-based research project by the North Carolina […]

(Beyond Pesticides, September 24, 2024) Recent commentary in Frontiers in Toxicology by two researchers, Maricel Maffini, PhD and Laura Vandenberg, PhD, highlights the pitfalls in the current regulatory systems in the United States (U.S.) for chemicals that threaten human health. Despite many advancements in science over the past few decades, and the wealth of studies that tie chemical exposure to negative health effects, risk assessments, and subsequent risk management, remain “static” and “outdated,” according to the authors. “There is increasing concern amongst public health professionals, environmental health scientists, and medical organizations about exposures to synthetic chemicals,” the researchers say. “These organizations’ concerns are based on the overwhelming evidence showing associations between chemical exposures and adverse health outcomes in human populations.” Such concerns have sparked a debate on current regulatory methods for chemicals that are present in highly used products, such as pesticides, plastic containers, and food.    The authors continue, “There are now thousands of studies showing associations between these chemicals and adverse health effects in humans including neurological disorders and learning disabilities, metabolic outcomes, infertility, thyroid dysfunction, and cancers.” Additional health effects can be seen in the Pesticide-Induced Diseases Database. Of the many harmful chemicals, per- and polyfluoroalkyl substances […]

(Beyond Pesticides, September 19, 2024) An article published in the journal Science of the Total Environment finds that the European Union’s (EU) risk assessment process, required for registration, fails to accurately or reliably predict pesticide exposure rates, sometimes by several orders of magnitude. Pesticide registration in the EU leverages the Agricultural Operator Exposure Model (AOEM)—a predictive model developed in 2014 to estimate expected non-dietary pesticide exposure levels for operators [pest control operators in the U.S.] based on a very limited set of data generated by the pesticide industry. Models that predict real-world exposure and underestimate field data raise critical questions about the efficacy of risk assessment reviews that determine product labels and allowed level of harm. By comparing the dermal exposure measured during a field study conducted in a nonagricultural area with the corresponding values estimated by AOEM, researchers in France add to the body of scientific literature indicating that the fossil fuel and petrochemical pesticide industry data cannot be relied upon as a benchmark to ensure public health and safety. The study describes the difficulty and complexity of calculating the ability of protective equipment to provide protection. According to the authors, “[AOEM] underestimated hand exposure by 42 times and […]

(Beyond Pesticides, August 30, 2024) There is no more compelling reason to embrace a precautionary pesticide poisoning standard this Labor Day than the need to protect workers. In fact, the Occupational Safety and Health Administration (OSHA) says on its website, Transitioning to Safer Chemicals, that the best way to protect workers is to  “eliminate or reduce hazardous chemicals at the source.” While some try to employ product substitution with “safer” chemicals, Beyond Pesticides urges decision makers to embrace alternative systems, such as organic management systems, that embrace management techniques to meet disease and infestation management goals and use only organic compatible substances. According to OSHA: “In chemical management, [the industrial hygiene principle, known as the hierarchy of controls] guides employers and workers to eliminate or reduce hazardous chemicals at the source by substituting them with safer alternatives. Unlike traditional engineering controls, administrative controls, work practice controls, or personal protective equipment, these strategies can completely eliminate exposure to hazardous chemicals, reduce the potential for chemical accidents, reduce disposal costs, and remove concerns regarding worker compliance and equipment maintenance.” A look through the state and federal databases that track occupational pesticide poisoning for both acute (immediate short-term) and chronic (long-term) pesticide effects […]

(Beyond Pesticides, August 21, 2024) A literature review, published this month in the Journal of Agricultural and Food Chemistry, explores levels of pesticide residues found in samples of human urine with environmental exposure and dietary intake and confirms prior findings about the benefits of an organic diet. Similar to past findings, lower concentrations of chemicals are detected in the urine of participants who report eating an organic diet. By analyzing 72 scientific research studies published between 2001 to 2023, the review assesses routes of exposure and “explores urinary concentrations and detection frequency of metabolites of organophosphates and pyrethroids, as well as herbicides such as 2,4-D and glyphosate,” the authors say. While “exposure to pesticide residues is influenced by a variety of demographic factors, including occupation, agricultural practices, seasonal variations, residence, diet, age, and gender,” the authors say, the concentrations of pesticides and their metabolites in human urine highlights the disproportionate risk to certain groups as well as the overall threat to the health of humans and the environment. Pesticide exposure can occur from dermal/skin contact or inhalation, through residence or work, and with dietary intake. “Pesticides in urine can be detected as parent compounds, specific metabolites corresponding to a specific […]

(Beyond Pesticides, July 16, 2024) Yet another study in the August 2024 journal Ecotoxicology and Environmental Safety has found that exposure to organophosphorus pesticides (OPPs) is correlated with increased suicidal thoughts in some people. This study is just the latest in a long line of studies from around the world that have linked pesticide exposure to mental health conditions, including sleep disorders, depression, and suicidal ideation (SI). As the rate of suicide increased by 30% between 2000 and 2020, there is an urgent public health need to investigate and address all potential contributing factors. A 2019 study, covered in Daily News, found that teens and adolescents living in agricultural areas and exposed to organophosphate (OP) insecticides are at higher risk of depression, In July and January this year, other studies link farmer psychiatric episodes to pesticide exposure, adding to the body of science. Exposure to household pesticides is also linked to depression in a 2020 study.   Study and Methodology  The study entitled “Association between exposure to organophosphorus pesticide and suicidal ideation among U.S. adults: A population-based study,” analyzes information on the mental and physical health of over 5,000 individuals aged 20 and up in the United States. The study aims […]

(Beyond Pesticides, July 2, 2024) Men’s Mental Health Awareness Month, which took place last month, evokes concern about the growing body of science linking pesticide exposure to neurological effects linked to depression. Recent studies reveal elevated rates of psychiatric disorders, including suicide, among farmers, with problems more common for males.  Through systematic reviews, meta-analyses, surveys and interviews, and blood sampling, these three studies add to the growing body of science linking pesticide exposure to neurological impacts. First, in the Journal of Agromedicine, researchers from Greece and the United Kingdom review eight studies and find a significant positive association between pesticide poisoning and depression in agricultural populations.1 Second, a study in Toxicology shows a link between depression in Brazilian farmers and pesticide exposure, most notably with glyphosate usage.2 Third, the latest study in Environmental Toxicology and Pharmacology focuses on work by researchers from Spain in identifying farmers exposed to chlorpyrifos, mancozeb, and malathion that have higher rates of depressive symptoms and suicide attempts.3  Through a meta-analysis of published research, the authors of the Agromedicine journal article identify pesticide poisoning as a risk factor of depression. With depression affecting more than 264 million individuals worldwide, this is a field of interest with […]

Calls for Holistic Environmental Justice and a Shift Away from Societal Dependence on Petrochemical Pesticides and Fertilizers (Beyond Pesticides, June 18-19, 2024) Juneteenth (June 19) commemorates the date in 1865 when the enslavement of Black Americans ended in the westernmost Confederate state of Texas, over two and a half years after the Emancipation Proclamation of 1863 and the defeat of the Confederacy on April 9, 1865. On June 19, 1865, Union Major General Gordon Granger brought federal troops to Galveston, Texas and finally, and belatedly, implemented the Emancipation Proclamation, which proclaimed on January 1, 1863 freedom from slavery across the nation. Carl Mack, PhD, a historian and former President of the Seattle-King County NAACP, reminds us that there were still 225,000 enslaved Black Americans in Kentucky and Delaware after June 19, 1865 and the end of the Civil War until December 6, 1865 when Georgia became the 27th state to ratify the 13th amendment. “That is the day in which Georgia ratified the 13th amendment,” Dr. Mack goes on to discuss the remaining three former border states on their progress in adopting the 13th amendment. “As it applies to Delaware and Kentucky, Delaware did not ratify the 13th amendment until […]

(Beyond Pesticides, June 11, 2024) Published in Science of The Total Environment in May, a comprehensive literature review of population-based studies finds strong linkages between direct and acute pesticide exposure and elevated risk of breast cancer (BC). A majority of the studies analyzed in this review were based on population groups in the United States, but also extends to Australia and three European countries (Greece, France, and Italy). Included in these studies are women who worked in chemical-intensive agricultural settings, directly sprayed pesticides in their at-home gardens, and/or handled pesticide-contaminated clothing. The findings in this literature review underscore organic advocates’ concerns of relying on pesticide substitution models that inevitably impact the health of land stewards, farmers, farmworkers, and the broader public rather than transforming food systems to an organic model that bans the use of toxic petrochemical-based pesticides. The goal of this review was to synthesize existing literature on pesticide exposure and breast cancer to determine the specific pathways and underlying mechanisms that contribute to female participants’ heightened risk. This literature review was published online by researchers at the University of Arizona’s R. Ken Coit College of Pharmacy and Coit Center for Longevity and Neurotherapeutics and the Laboratory of Tumor […]

(Beyond Pesticides, May 15, 2024) A study published recently in the journal Environmental Research finds a significant correlation between exposure to certain pesticides and an elevated risk of inflammatory bowel disease (IBD), a chronic autoimmune condition of the gastrointestinal tract. The study, adding to the body of science on this subject, evaluates self-reported data from licensed pesticide applicators and their spouses exposed to pesticides for over 20 years. In addition, while some of the chemicals found to be most closely associated with incidents of IBD have been banned from use, they are “forever” chemicals that persist in the environment for generations. These findings demonstrate once again the failings of the current regulatory process to identify hazards before they are put into the environment. The study found evidence that exposure to several organochlorine insecticides (dieldrin, DDT, and toxaphene), as well as organophosphate insecticides (parathion, terbufos, and phorate) and herbicides (2,4,5-T, 2,4,5-TP, and metolachlor), is associated with elevated IBD risk. IBD is a generic term for diseases that result in chronic inflammation of the gastrointestinal tract, such as Crohn’s disease and ulcerative colitis. It is estimated that 6.8 million patients globally suffered from IBD in 2017. IBD may result from an imbalance […]

(Beyond Pesticides, May 3, 2024) Parkinson’s disease (PD) is the second most common neurodegenerative disease in the world after Alzheimer’s. Genetic factors account for only a fraction of PD cases, and for decades scientists have been aware of associations between pesticide exposures and PD. Yet, not everyone exposed to pesticides gets PD. Consequently, neither the genetic nor the environmental hypothesis is fully satisfactory; both may be involved. Thus, there has been great interest in identifying gene variants that affect the risks of PD associated with pesticide exposure. Now a team of University of California at Los Angeles researchers led by neurologist Brent Fogel, MD, PhD has traced a connection between certain gene variants and the occurrence and severity of PD in a cohort of central California PD patients who have had long-term exposure to pesticides. The genes are related to autophagy, the process by which cells organize, degrade, recycle or eject molecules to maintain healthy chemical balance. Autophagy is an essential process throughout the body, including regulation of mitochondria, which are also vital for healthy cellular function. The study supports other research suggesting that autophagy is disturbed in neurodegenerative diseases. As Beyond Pesticides discussed in its April 19 Daily News, PD […]

(Beyond Pesticides, May 1, 2024) According to a new analysis by Consumer Reports, the U.S. Department of Agriculture (USDA) Pesticide Data Program (PDP) Annual Summary has once again failed to accurately portray the safety of some of the most commonly sold fruits and vegetables in the United States. A review of seven years of PDP data show that 20% of the foods tested pose a “high risk” to the public and 12 specific commodities are so dangerous that children or pregnant people should not eat more than one serving per day, according to Consumer Reports analysis. Consumer Reports contend that U.S. Environmental Protection (EPA) pesticide residue tolerances are too lenient. To better evaluate potential health risks associated with various foods, Consumer Reports applied stricter residue limits than the EPA tolerances (see here for CR’s analytical methodology). Notably, USDA certified organic food products are not permitted to be produced with the pesticides identified by the report. Pesticide residues found in organic, with rare exception, are a function of the off-target chemical-intensive agriculture pollution through pesticide drift, water contamination, or background soil residues. The Consumer Reports results fly in the face of the rosy outlook reported by the USDA in its 2022 […]

(Beyond Pesticides, April 29, 2024) The contamination and poisoning left behind from wood treatment sites, resulting in hundreds of designated Superfund clean-up sites across the country, is the subject of an action by Beyond Pesticides after the release of yet another report criticizing the federal government’s inadequate response to the public’s risk to “residual contamination in the groundwater and soil” by the U.S. Environmental Protection Agency (EPA) Office of Inspector General (OIG). The report criticizes EPA’s weak response at the American Creosote Works Superfund site in Pensacola, FL, a problem that reflects the unending dangers of sites contaminated with persistent toxic chemicals associated with wood preservatives. The site was put on the Superfund priority list in 1983 and in 2017 it was estimated that the clean-up would cost $35.3 million. Just last year, EPA Administrator Michael Regan toured another Superfund Site contaminated with creosote and pledged the clean-up of that site, which affects a community of predominantly people of color. Tell EPA to cancel the registration of highly toxic wood preservatives, including creosote, chromated arsenicals, and copper compounds, and the U.S. Congress to ensure the prevention of future site contaminations. As long as dependency on toxic wood preservatives (used on utility […]

(Beyond Pesticides, April 25, 2024) In a study from earlier this year, “Pesticides: An alarming detrimental to health and environment,” scientists compiled research from 154 articles regarding pesticide use and the adverse effects they have on the environment and human health. Among the effects of the harmful pesticides described is genotoxicity—the alteration of genetic material that results in the mutations in DNA that cause cancer.  The authors state that “genotoxins are mutagenic chemicals, and exposure to them increases the risk of developing tumors, hormonal changes, DNA damage, and changes in the ovaries and eggs, all of which leading to cancers… The risk of DNA damage surges with increased genotoxicity in people exposed to pesticides.” In addition, the National Institute of Health states that all “pesticides are highly biologically active chemicals. They may interact with DNA and damage its structure.” Despite these documented risks, pesticide use continues to surge.  While phased out to a considerable extent after being widely used in agriculture and residential areas, organochlorine pesticides (OCPs) like dichlorodiphenyltrichloroethane (DDT) or its breakdown compound dichlorodiphenyldichloroethylene (DDE) continue to show up as residues in the environment and food supply. Symptoms in humans that have been exposed to these chemicals include: seizures, […]

(Beyond Pesticides, April 24, 2024) On April 16, 2024, the U.S. Environmental Protection Agency (EPA) posted an “update” to the Draft Herbicide Strategy Framework (Draft Herbicide Strategy Framework to Reduce Exposure of Federally Listed Endangered and Threatened Species and Designated Critical Habitats from the Use of Conventional Agricultural Herbicides) that was released last summer, weakening aspects of the agency’s efforts to “protect” endangered species from herbicide use. The update outlines three types of modifications to the Draft Strategy, including “simplifying” its approach, increasing growers’ “flexibility” when applying mitigation measures, and reducing the mitigation measures required in certain situations. By reducing the stringency of the Strategy, advocates are again questioning EPA’s commitment to fulfilling legal requirements under the Endangered Species Act (ESA) or protecting endangered species and their habitats in the midst of an unprecedented rate of global extinction. ESA is celebrated as one of the most far-reaching conservation laws globally, credited with preventing the extinction of 99 percent of those species the government targets for protection, according to the U.S. Fish and Wildlife Service (USFWS). ESA establishes a framework to categorize species as “endangered” or “threatened,” granting them specific protections. Under ESA, EPA is required to consult with relevant agencies […]

(Beyond Pesticides, April 17, 2024) With headlines drawing public attention to the contamination of drinking water after years of federal government neglect, the U.S. Environmental Protection Agency (EPA) announced on April 10 new standards to reduce public exposure to PFAS, or per- and polyfluoroalkyl substances, commonly referred to as “forever chemicals” because of their persistence. EPA has finalized a National Primary Drinking Water Regulation (NPDWR) for six PFAS, including PFOA and PFOS, which EPA has recognized have no safe level of exposure, regulating new chemicals for the first time since the 1996 amendments to the Safe Drinking Water Act (SDWA). PFAS persistence and bioaccumulation in humans, wildlife, and the environment is due to the strength of a resulting fluorine–carbon atom bond. PFAS contamination of drinking water, surface and groundwater, waterways, soils, and the food supply—among other resources—is ubiquitous worldwide. PFAS is used in everyday products, including cookware, clothes, carpets, as an anti-sticking and anti-stain agent, in plastics, machinery, and as a pesticide. The action was welcomed by environmentalists and public health advocates as an important step but left many concerned that any level of exposure to these chemicals is unacceptable and critical of EPA’s ongoing failure to act despite years […]