Archive for the 'Disease/Health Effects' Category
23
Jun
(Beyond Pesticides, June 23, 2026) With new medications (including those containing GLP-1-receptor-agonist or glucagon-like peptide-1) exploding onto the market to treat obesity and serious related health threats, it is easy to lose sight of critical policy issues that allow the ongoing introduction of obesogenic pesticides and other chemicals (endocrine disrupting chemicals that affect metabolism and fat storage) into the food supply. The science on obesity has found that the most common form is attributable to a combination of genetic and environmental factors. Because there are many factors, the blame for the obesity epidemic cannot be attributed solely to diet broadly, but may relate directly to pesticide and toxic chemical exposures, including chemical residues in food, that may lead to Type 2 diabetes, heart disease, high blood pressure, kidney failure, a breakdown of cartilage and bone within joints, and other metabolic disorders. An increasing body of research shows that exposure to certain pesticides and environmental contaminants initiates various changes in metabolism leading to obesity—not only in the exposed person, but also in offspring.  With all the media attention on a medical cure for obesity, Beyond Pesticides has launched an action to: Urge lawmakers and policymakers to support policies that contribute to obesity prevention by eliminating […]
Posted in Endocrine Disruption, Epigenetic, Epigenetic Effects, Metabolic Disorders, Obesity, Take Action, Uncategorized | 6 Comments »
18
Jun
(Beyond Pesticides, June 18-19, 2026) Friday, June 19 is Juneteenth, a commemoration of the abolition of slavery and a celebration of human freedom. “Injustice anywhere is a threat to justice everywhere,” Reverend Doctor Martin Luther King, Jr proclaimed. This truth raises societal concerns of continuing systemic environmental racism and institutional failures of predominantly white institutions and the need to protect those at disproportionate risk, specifically Black, Indigenous, and People of Color (BIPOC) communities, from agricultural and industrial pollution. [Juneteenth is a celebration of freedom for the last 250,000 enslaved people in Galveston, Texas, but it is also a reminder that justice has not historically been “swift” or complete for Black Americans. The holiday commemorates the abolition of slavery in Texas on June 19, 1865, two and a half years after the Emancipation Proclamation. Juneteenth, officially recognized as a federal holiday since 2021, commemorates the arrival of Union soldiers in Galveston, Texas, to free enslaved people per the Emancipation Proclamation that was issued two and a half years prior. While June 19, 1865, does not mark the legal end of slavery nationwide, it was a crucial moment in the fight for freedom and continues to highlight the ongoing fight for human […]
Posted in Breast Cancer, Cancer, Environmental Justice, Environmental Protection Agency (EPA), Holidays, Uncategorized | No Comments »
17
Jun
(Beyond Pesticides, June 17, 2026) A study out of Michigan State University reviews robust county-level data on pesticide use and breast cancer incidence rates, determining that there are “modest positive associations” in rural counties in the United States. The findings were published in Cancer Causes & Control. Public health and environmental advocates cite the proliferation of published, peer-reviewed research, like this new study, in support of a societal imperative to eliminate harmful agrichemicals and transition to organic practices. The U.S. and countries worldwide have standards for certified organic production, similar to the U.S. Organic Foods Production Act, that establish required practices, a national list of allowed and prohibited substances, public oversight and a stakeholder board with authority over allowed inputs, certification and inspection of on-farm practices, and an enforcement system to ensure standards compliance. There is limited federal investment in growing the organic sector, despite its productivity, profitability, and protection of healthy ecosystems. The study adds to the body of science that illustrates dramatic deficiencies in the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) under which the U.S. Environmental Protection Agency (EPA) and other federal statutes fall short in addressing the complex exposure patterns and adverse human and environmental effects, […]
Posted in acetamiprid, Aldicarb, Atrazine, Azinphos-methyl, Bensulide, Breast Cancer, carbamate, Carbamates, Carbaryl, Chlorpyrifos, Clothianidin, cypermethrin, Diazinon, dicofol, Dimethoate, dinotefuron, Disease/Health Effects, Disulfoton, Endosulfan, Ethoprop, Fenamiphos, fenpropathrin, Fosetyl, glufosinate, Glyphosate, Imidacloprid, Lindane, Malathion, methoxychlor, Naled, neonicotinoids, organochlorines, organophosphate, Parathion, Permethrin, Propazine, Propoxur, pyrethroids, simazine, terbufos, thiacloprid, Thiamethoxam, Triazines, Tribufos, Triclopyr, U.S. Geological Survey, Uncategorized, Women's Health | 1 Comment »
16
Jun
(Beyond Pesticides, June 16, 2026) If there is one take-home message regarding reducing risk of childhood leukemias and brain cancers, it is to avoid exposure to pesticides during pregnancy—especially indoor insecticides such as flea and tick products, including DEET, household plant and commercial pesticide treatments, and proximity to pesticide applications in agriculture. A review by researchers at the University of Nebraska Medical Center and School of Natural Resources in Omaha considered 88 epidemiological papers published between 1980 and 2022 on pediatric cancer and environmental pesticide exposure and found elevated rates of pediatric cancers associated with pesticide exposure. The reviewers assessed the known associations between the risk of childhood leukemia and brain tumors and their or their parents’ exposure to pesticides, pesticide breakdown products and mixtures. They asked how important known exposures in drinking water were to the children’s risk, and whether genetics is a primary influence on cancer development. The researchers found that the risk of childhood brain tumors increased 1.5 times if pest control products were applied during the entire year before conception. High-grade glioma risk was four times higher when pesticides were applied during pregnancy. Prenatal exposure to flea and tick products raised risk, especially for children diagnosed under […]
Posted in Agriculture, Brain Effects, Cancer, Children, DEET, Disinfectants & Sanitizers, Leukemia, Reproductive Health, Uncategorized, Water | No Comments »
11
Jun
(Beyond Pesticides, June 11, 2026) A study of honey bee colonies in Florida and California, published in Environmental Toxicology and Pharmacology, finds elevated mortality from pesticide residues, including those that have been documented to threaten pollinators. As the authors describe, “While bees die from multiple, often interacting, stressors, here we show single contributors at levels capable of causing acute harm.” The presence of miticides, fungicides, herbicides, and insecticides within the bee colonies, including in the bodies of dying bees, further highlights pesticides as drivers of bee declines. By sampling both dying bees and in-house bees for chemical residues, the researchers are able to compare symptomatic colonies and control colonies. The authors note, “Our findings differ from previous screenings, which cast a broad net, screening agrochemicals in colonies nationwide, and not necessarily from impacted operations.” This study, however, shows the presence of specific pesticide residues in commercially managed colonies after die-off incidences. The neonicotinoid insecticide imidacloprid, in particular, is widely detected and found in high levels, with the researchers identifying the compound as the largest contributor to bee death. Background Scientific literature linking pesticides, including neonicotinoids, to adverse impacts on pollinators continues to mount, as do the devasting population declines of […]
Posted in Agriculture, Beneficials, Biodiversity, California, Death, Ecosystem Services, Florida, Fungicides, Herbicides, Imidacloprid, Insecticides, neonicotinoids, Pesticide Residues, Pollinators | No Comments »
10
Jun
(Beyond Pesticides, June 10, 2026) Adding to the wide body of science connecting the weed killer paraquat to deleterious health and environmental effects, Investigate Midwest recently released an investigative news article connecting air emissions of paraquat from chemical plants in the Mississippi Basin to Parkinson’s disease, among other adverse health effects. The herbicide is also fatal to humans with a single sip, as documented in the article, entitled “This herbicide is so toxic it’s been banned in over 70 countries. But plants in the South are releasing it into the air.” In capturing the story of Wayne County, Mississippi, where approximately 20,000 people live surrounded by forest and farmland, Investigate Midwest sheds light on the connection between the Sipcam Agro plant that processes and emits paraquat. The plant is located in the county with among the highest U.S. rates of Parkinson’s disease deaths, the top 7% of all U.S. counties. Background on Paraquat Paraquat has been on the market since the 1960s, created by a predecessor of Syngenta. In March of this year, Syngenta announced it would stop producing paraquat in the UK after thousands of lawsuits, primarily by farmers and farmworkers, cite Syngenta’s failure to warn of adverse health effects like Parkinson’s disease. Stopping the production of paraquat in the UK will not prevent paraquat from entering the U.S., as “other companies and other facilities—like the one in Wayne County—will fill the gap, likely increasing the amount of paraquat they handle.” According to previous data from the U.S. Geological Survey, approximately 11 to 17 million pounds of paraquat were sprayed annually in 2017, which may […]
Posted in Agriculture, air pollution, Herbicides, Mississippi, Paraquat, Parkinson's, Syngenta, Vermont | 2 Comments »
09
Jun
(Beyond Pesticides, June 9, 2026) In a new literature review published in Florence Nightingale Journal of Nursing, researchers identify 10 peer-reviewed studies with a statistically significant relationship between pesticide exposure and declines in cognitive function among agricultural workers. The cognitive deficits adversely impact their daily functioning and safety on the job. These adverse impacts include disruptions to visual memory, attention, language speaking, and perceptual-motor function. Two of these studies specifically compare chemical-intensive and organic farmers, finding a relationship between less synthetic pesticide exposure and improved neurological and cognitive outcomes. While more data is needed to produce precise dose-response estimates by active ingredient/chemical mixture, the findings support a precautionary approach to pest management decisions and transitioning to organic land management, a trend that is increasing across the U.S. and worldwide. Main Findings The researchers identify 12 studies published between 2016 and 2023 that assessed pesticide impacts—“including insecticides, fungicides, herbicides, bactericides, rodenticides, and nematodes”—on various areas of cognitive function in agricultural workers, with 10 of those studies showing a statistically significant relationship. The main findings include: Two studies compare organic and chemical-intensive farmers, with one study focused on Costa Rica (Mora et al., 2022) and the other focused on the United States […]
Posted in Alternatives/Organics, behavioral and cognitive effects, Body Burden, Disease/Health Effects, Drift, multi-generational effects, Occupational Health, Pesticide Drift, Uncategorized | No Comments »
05
Jun
(Beyond Pesticides, June 5, 2026) With increasing research covered by Daily News showing pesticides linked to epigenetic effects (alter gene expression), the mechanism has far-reaching implications for protecting health and the environment. It also raises issues related to the regulatory review process, which is inadequate in assessing this mechanism. Since the discovery of DNA, a principle called the “central dogma” has dominated genetics. This dogma states that genetic processes are a one-way street: only changes to DNA in germ cells (eggs and sperm) trigger processes in RNA and then proteins to effect changes in tissues and cells throughout the body. Any suggestion that environmental exposures, for example, could alter gene expression except in the first, exposed generation, was dismissed as “Lamarckian” and unscientific. And only changes to genes themselves could be inherited. The theory of epigenetics began developing in the 1950s, and it gradually became clear that gene expression was modifiable by external factors. Cells do have numerous ways of choreographing genes, determining which ones are turned on and off at which times and in which places. In fact, this choreography is absolutely necessary for the development of an individual from pre-conception through fertilization and the progress of an embryo to […]
Posted in Agriculture, Cancer, Environmental Protection Agency (EPA), Epigenetic, Epigenetic Effects, Pesticide Regulation, Reproductive Health, Uncategorized, vinclozolin | No Comments »
03
Jun
(Beyond Pesticides, June 3, 2026) A study, published in PeerJ today, by researchers from the University of Wisconsin-Madison in the U.S. and the University of Pisa in Italy, finds that the widely used fungicide fludioxonil and its breakdown products, including a â€forever chemical’ per- and poly-fluoroalkyl substance (PFAS), threaten environmental and human health. Through a review of scientific literature (from 2021-2025) of the ecological and health effects of fludioxonil, the authors find evidence of this chemical’s mechanisms of toxicity, including oxidative stress, that are enhanced as it degrades in the environment. Oxidative stress occurs when there is a disruption of normal cell-signaling and molecular damage, leading to an imbalance of reactive oxygen species (ROS) and free radicals (unstable oxygen molecules) that the body is unable to detoxify. In particular, sunlight exposure causes fludioxonil to break down into a PFAS that is linked to adverse health implications for the environment, wildlife, and humans. One of the authors, Warren Porter, PhD, is a board member for Beyond Pesticides and presented at the 2021 National Pesticide Forum. Dr. Porter is an emeritus Professor of Integrative Biology and an Ardath and Robert Rodale Professor of Environmental Toxicology, with previous research showing that combinations of commonly used agricultural chemicals in concentrations that mirror levels found in groundwater can significantly influence immune, endocrine, and neurological health in animals. His research also links pesticide exposure in utero to impaired learning, changes in brain function, and […]
Posted in Agriculture, Breakdown Chemicals, fludioxonil, Fungicides, Italy, Metabolites, Oxidative Stress, Pesticide Regulation, PFAS, Syngenta | No Comments »
01
Jun
(Beyond Pesticides, June 1, 2026) In the face of U.S. government inaction, the California state Assembly last week passed legislation to phase out existing agricultural uses and ban new uses of PFAS (perfluoroalkyl and polyfluoroalkyl substances) pesticides. The legislation, AB 1603, which accurately defines PFAS pesticides in accordance with international standards, does allow continued residential, school and park, playing field, and community PFAS pesticide use (including mosquito spraying). The bill now moves on to the state Senate. While advocates say the bill is an important step forward, they point out that the legislation is one of many examples that compromises public and environmental health, as pesticide-associated cancer, degenerative diseases, multigenerational effects, and ecosystem decline escalate. This attack on health and the environment is happening at the same time that organic agriculture and land management prohibits the use of PFAS pesticides and all the petrochemical pesticides and fertilizers with profitable and cost-effective practices. The California victory paves the way for state action as regulators at the U.S. Environmental Protection Agency (EPA) refuse to act on clear scientific findings identifying devastating health and environmental threats. In this context, the bill serves as a call for all states to push for this type of legislation […]
Posted in Agriculture, Alternatives/Organics, California, Disease/Health Effects, Drinking Water, Environmental Protection Agency (EPA), PFAS, Take Action, Uncategorized | No Comments »
26
May
(Beyond Pesticides, May 26, 2026) Earlier this month, with global attention focused on 12 known or suspected cases of hantavirus, including three deaths, on a cruise ship expedition in the South Atlantic, issues of rodent management, vector control, and disease transmission have made headlines around the world. The incident raises important questions about rodent biology, identification of virus location, method of disease transmission, cleaning practices, and ultimately control and prevention measures that are not harmful to people, wildlife, and ecosystems. The incident also shines a spotlight on the critical importance of the United States’ collaboration in international organizations, particularly the World Health Organization (WHO), in a world of international travel (18 on the ship live in the U.S.), where transmissible diseases extend beyond countries’ borders. With the Trump Administration defunding international programs and withdrawing from WHO, most medical experts agree that the world and U.S. residents are at heightened threat from transmissible diseases that move throughout the world. (See U.S. Abandons International Collaboration on Existential Health Challenges at Time When Most Needed.) In this context, Beyond Pesticides has launched a local campaign to Tell local officials to use good sanitation and management to prevent rodent problems and not use hazardous […]
Posted in Argentina, Centers for Disease Control and Prevention, Hantavirus, International, Mice, Rodenticide, Rodents, Take Action, Uncategorized, World Health Organization | No Comments »
22
May
(Beyond Pesticides, May 22, 2026) On Memorial Day, those who served and died in the armed forces are remembered for their ultimate sacrifice. And the victims of war are memorialized. Of critical note are the effects of war, that extend beyond the battlefield to those who return home or remain in the aftermath with post-traumatic stress disorder (PTSD) and ultimately take their lives by suicide, as well as those exposed to deadly chemicals that caused premature death. A 2022 study finds, “ VA [Veteran Affairs] patients with current or past diagnosis of PTSD have been found to have an unadjusted rate of 50.7 deaths by suicide per 100,000 person years of risk, compared to a rate of 13.2 in the general adult population.” This statistic can be evaluated in the context of a recent observational cohort study to be in print in August 2026 that focuses on exposure to toxic substances and suicidal thoughts and behaviors (STBs) through the analysis of data from 248,926 U.S. veterans enrolled in the Million Veteran Program (MVP). In comparing self-reported exposures to nine toxicants, including Agent Orange, chemical/biological weapons, anthrax vaccine, solvents/fuels, petroleum combustion products, lead, other metals, pesticides, and open-air burn pits, and […]
Posted in Cancer, Department of Defense, Gulf War Syndrome, Holidays, Suicide, Uncategorized | No Comments »
21
May
(Beyond Pesticides, May 21, 2026) An important study by cancer researchers in Barcelona, Spain at once shows a path forward in illuminating the long-term, multi-generational, health damage from pesticide exposures and demonstrates how extraordinarily dilatory U.S. agricultural regulators are in protecting public health. The study, “Epigenetic fingerprints link early-onset colon and rectal cancer to pesticide exposure,” found a robust association between methylation markers (for gene expression associated with cancer) and exposure to a number of pesticides, with the herbicide picloram having the strongest link. Other pesticides with strong associations include the weedkillers atrazine, glyphosate, nicosulfuron, and insecticide esfenvalerate. Colon cancer is expected to double, and rectal cancer to quadruple, in this young age group by 2030. This sharp contrast between age groups suggests that environmental exposures, rather than strictly genetics, are involved. The authors are concerned with the alarming rise in early onset colorectal cancer (EOCRC) not only in the highly developed world but also in less-industrialized countries. This increase appears to be connected with age cohorts and the differences in lifestyle and environmental exposures between older and younger cohorts. According to a commentary on the study by researchers from the Dana-Farber Cancer Institute, in the U.S., the incidence of colorectal […]
Posted in Agriculture, Atrazine, Cancer, Dow Chemical, Environmental Protection Agency (EPA), Epigenetic, esfenvalerate, Glyphosate, Groundwater, Herbicides, nicosulfuron, picloram, Uncategorized | No Comments »
20
May
(Beyond Pesticides, May 20, 2026) A study of two pollinator species, honey bees (Apis mellifera) and small carpenter bees (Ceratina calcarata), finds oxidative stress (OX)— an imbalance between antioxidant defenses and excess reactive oxygen molecules (species), or ROS—resulting from exposure to non-living (abiotic) stressors, such as synthetic chemicals, leading to cell damage. Regulatory bodies, including the U.S. Environmental Protection Agency (EPA), do not routinely evaluate oxidative stress as a standalone or required endpoint in standard pesticide registration protocols. In comparing pollinator responses to different pesticides and pest control management practices, the lowest levels of OX are exhibited in organically managed systems, as described in the research published in Physiological Entomology. Quantifying the oxidative stress levels in bees and their larval stages from three landscapes (conventional, organic, and roadside) shows that minimum exposure to agrochemicals and high traffic-related pollutants results in the lowest levels of OX. “Overall, these findings show that variation in pesticide residue profiles across landscapes is associated with different OX responses in bees,” the authors state. “Given the essential ecosystem services provided by bees, our findings underscore the urgent need for landscape-level strategies to reduce pollinator exposure to chemical stressors.” Background Oxidative stress occurs when there is a […]
Posted in Agriculture, Alternatives/Organics, Beneficials, Biodiversity, Ecosystem Services, Oxidative Stress, Pollinators, Wildlife/Endangered Sp. | No Comments »
18
May
(Beyond Pesticides, May 18, 2026) As the studies continue to mount on the adverse effects of exposure to low levels of organophosphate insecticides, the calls for banning the chemicals are growing. Beyond Pesticides announced an action to “Tell Congress, FDA, and EPA that it is past time to stop the manufacture and use of all organophosphate pesticides, which damage the nervous system and brain at low levels.” There are alternatives to these chemicals that support productive and profitable farming operations. Defying the often-repeated claim that organophosphate pesticide effects occur only at high doses, a recent study by researchers at University of California, San Diego, and the FundaciĂłn Cimas del Ecuador in Quito, Ecuador, establishes for the first time the pattern of adverse developmental effects that low-level exposure has on healthy neurological and brain development in children. It is firmly established that widely used organophosphate pesticides in food production and other sites are severely toxic to a broad range of organisms. In what is known as their “classic” mechanism of action, they inhibit acetylcholinesterase (AChE), an enzyme that breaks down the neurotransmitter acetylcholine (ACh), particularly in neuromuscular junctions in the brain. Organophosphates are nerve agents, originally developed by the German company IG Farben (a […]
Posted in ADHD, Agriculture, BASF, Bayer, behavioral and cognitive effects, Brain Effects, Children, Chlorpyrifos, Corteva, Developmental Disorders, Dow Chemical, Environmental Protection Agency (EPA), Epigenetic Effects, Immunotoxicity, IQ Loss, Nervous System Effects, organophosphate, Take Action, Uncategorized | No Comments »
13
May
(Beyond Pesticides, May 13, 2026) Published in Toxics, a review finds that per- and polyfluoroalkyl substances (PFAS) can heighten the risks to exposed organisms from environmental contaminants. Mixtures of these compounds can negatively impact the nervous, cardiovascular, immune, and reproductive systems, particularly in aquatic organisms, and threaten overall biodiversity. The review highlights synergistic effects (greater in combination) observed in mixtures, such as PFAS with pesticides and microplastics, that can cause enhanced oxidative stress, neurotoxicity, developmental defects, and reproductive dysfunction, among others. “The objectives were to evaluate the toxicological effects of mixtures of the selected contaminants with PFAS on aquatic organisms to better understand biological responses in animals,” the study authors explain. “Based on our review, data suggest that PFAS can modify the toxicity of co-occurring pollutants.” Background PFAS were first created in the 1930s and have since been used in many industries and in the production of many products. The multitude of PFAS sources and exposure routes leads to widespread contamination of the environment and organisms. PFAS in agriculture represents a large source, as PFAS can be pesticide active ingredients, used in the plastic containers that pesticides are stored in, and as surfactants in pesticide products. Additionally, PFAS are used in many other […]
Posted in Agriculture, Aquatic Organisms, Atrazine, Biodiversity, Body Burden, Chemical Mixtures, Chlorpyrifos, contamination, Developmental Disorders, fish, Oxidative Stress, PFAS, Reproductive Health, synergistic effects, Water | No Comments »
08
May
(Beyond Pesticides, May 8, 2026)  A study from Ecuador establishes for the first time the developmental pattern of nervous system toxicants—still widely used in agriculture, mosquito control, and landscaping—on healthy neurological and brain development in children. It is firmly established that widely used organophosphate pesticides are severely toxic to a broad range of organisms. In what’s known as their “classic” mechanism of action, they inhibit acetylcholinesterase (AChE), an enzyme that breaks down the neurotransmitter acetylcholine (ACh), particularly in neuromuscular junctions in the brain. Not enough AChE leads to a buildup of ACh in motor neurons. Organophosphates deplete AChE, and an acute dose can paralyze the heart and lung muscles, causing death. Chronic exposures are implicated in numerous neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and amyotrophic lateral sclerosis (ALS). Beyond Pesticides’ Gateway on Pesticide Hazards and Safe Pest Management has detailed information on the organophosphates malathion, chlorpyrifos, diazinon, and others. Acetylcholine and AChE are vital biological chemicals conserved across the animal kingdom, from humans to insects and everything in between. Yet there is no established baseline for normal levels of ACh and AChE in humans. Comparing biomarkers of organochlorine exposure with normal values would be a major step forward in assessing the influence […]
Posted in Brain Effects, Children, Developmental Disorders, Insecticides, Lawns/Landscapes, Nervous System Effects, Pesticide Drift, Uncategorized | No Comments »
07
May
(Beyond Pesticides, May 7, 2026) Adding to the wide body of science on pesticide-induced cancer, researchers from the Icahn School of Medicine at Mount Sinai’s Department of Hematology and Medical Oncology and Department of Environmental Medicine find that environmental and occupational exposures increase the risk of developing multiple myeloma (MM), a type of blood cancer. As published in Blood Reviews, the literature review highlights how exposure to contaminants, such as pesticides, dioxins, combustion byproducts, and ambient air pollution, can cause MM through mechanisms of oxidative stress, DNA damage, and aryl hydrocarbon receptor signaling, as well as influence disease biology through immune dysregulation. “Earlier epidemiologic studies suggested associations between environmental exposures and disease risk, but few have used modern geospatial or exposomic [totality of environmental exposure relating to health effects] methods capable of capturing exposure complexity,” the authors write. They continue: “Advances in data integration, spatial modeling, and molecular profiling now make it possible to revisit these questions with greater precision and biological context. This review summarizes current evidence on environmental exposures in plasma cell disorders and frames a research agenda for integrating exposomic data to improve exposure resolution and evaluate plausible mechanisms in MM.” Background Multiple myeloma is an incurable […]
Posted in Agent Orange, Agriculture, Blood Disorders, Cancer, Carbaryl, DNA Damage, Multiple Myeloma, Oxidative Stress, TCDD | No Comments »
06
May
(Beyond Pesticides, May 6, 2026) Adding to the wide body of science highlighting the adverse effects of pesticides on pollinators, as extensively documented in Daily News and What the Science Shows on Biodiversity, a study published in Insects finds threats to Italian honey bees (Apis mellifera ligustica) following exposure to insecticides with contrasting toxicity levels. Both the high toxicity and low toxicity compounds impact honey bee gut bacteria and gut microbial composition, showing how even “reduced risk” insecticides can have sublethal effects and jeopardize pollinator health. As the authors point out, “Honey bees depend on a small but highly specialized community of gut bacteria that help them digest food, resist infections, and cope with environmental stress.” Because of this, chemicals that disrupt the honey bee gut microbiome can threaten their survival. In the current study, the researchers analyze two compounds to determine adverse impacts on honey bees’ gut microbiota: emamectin benzoate-lufenuron (EB-LFR), an avermectin insecticide with high toxicity, and RH-5849 (1,2-dibenzoyl-1-tert-butylhydrazine), a non-steroidal ecdysone agonist (mimicking the action of the insect molting hormone) and insect growth regulator with reported lower toxicity. The results reveal that both toxicity levels can harm gut microbial composition, with EB-LFR “associated with observed reductions in […]
Posted in Agriculture, Beneficials, Biodiversity, emamectin, Gut Dysbiosis, Insecticides, Microbiome, neonicotinoids, Pollinators | 1 Comment »
01
May
(Beyond Pesticides, May 1, 2026) A study in Psychiatry Research, entitled “Toxic Exposure and Rates of Suicidal Thoughts and Behaviors Among U.S. Military Veterans,” adds to the body of science linking poorer mental health among military members with exposure to environmental contaminants. While previous research focuses on mental health broadly, the current observational cohort study focuses on exposure to toxic substances and suicidal thoughts and behaviors (STBs) through the analysis of data from 248,926 U.S. veterans enrolled in the Million Veteran Program (MVP). In comparing self-reported exposures to nine toxicants, including Agent Orange, chemical/biological weapons, anthrax vaccine, solvents/fuels, petroleum combustion products, lead, other metals, pesticides, and open-air burn pits, and mental health records, the researchers find that military veterans with higher toxic exposures are more likely to have STBs. The authors also report that these associations occur across all major service cohorts (pre-Vietnam, Vietnam, post-Vietnam, Gulf War, and post-9/11 eras). “Our work contributes to growing evidence that veterans who report more toxic exposures are more likely to have STBs, consistent with greater risk for other mental health outcomes (e.g., depression, PTSD [post-traumatic stress disorder]),” the researchers conclude. Importance and Background Military members experience increased health risks with exposure to environmental […]
Posted in Agent Orange, air pollution, Brain Effects, contamination, Depression, Gulf War Syndrome, Occupational Health, Parkinson's, PFAS, Suicide | No Comments »
28
Apr
(Beyond Pesticides, April 28, 2026) In Chemical Research in Toxicology, researchers from the Universitat Rovira i Virgili in Catalonia, Spain highlight the threats to human and environmental health with “combined exposures to multiple chemical toxicants, including industrial chemicals, heavy metals, pesticides, endocrine-disrupting chemicals (EDCs), and per- and polyfluoroalkyl substances (PFAS).” As these compounds are encountered in mixtures in real-world settings, the resulting interaction can have additive or synergistic effects that risk assessments fail to adequately capture. As the authors point out: “This leads to a systematic underestimation of health risks, particularly for vulnerable populations. Despite robust evidence on mixture toxicity, major regulatory frameworks such as the U.S. Toxic Substances Control Act (TSCA) and the EU’s [European Union] REACH program continue to assess chemicals in isolation.” Importance and Background Environmental toxicants are ubiquitous throughout nature and within all organisms. In humans, these compounds can accumulate, referred to as ‘Body Burden’, which encompasses numerous chemicals such as pesticide mixtures. “Critically, organisms are rarely exposed to a single chemical in isolation,” the researchers note. “Rather, they continuously encounter complex mixtures of contaminants whose combined effects may differ substantially from those predicted by examining each substance individually.” As the authors explain, regulatory agencies underestimate […]
Posted in Agriculture, Alternatives/Organics, Biodiversity, Body Burden, Chemical Mixtures, Endocrine Disruption, Environmental Protection Agency (EPA), European Union, Pesticide Mixtures, Pesticide Regulation, PFAS, synergistic effects | No Comments »
24
Apr
(Beyond Pesticides, April 24, 2026) In a review of scientific literature documenting pesticide contamination in the atmosphere, international researchers find human and ecosystem exposure even in remote and distant areas. As published in the Journal of Hazardous Materials, the authors state: “Atmospheric transport of pesticides is a globally significant yet widely underestimated driver of human and ecological exposure, with contamination documented far beyond treated fields. This review provides a novel integrated synthesis, bridging emission pathways, atmospheric transformation processes, monitoring evidence, model limitations, and regulatory gaps to deliver a comprehensive understanding of the fate and impacts of pesticides in the atmosphere.” In analyzing the current knowledge on pesticide emissions, through both drift and volatilization (process where a solid or liquid converts into a gas or vapor), the researchers highlight “the widespread detection of both current-use and banned pesticides in environmental matrices far from their application,” along with the resulting implications for human health and environmental health. As the current risk assessment framework “fails to adequately address the perturbations caused by the atmospheric transport of pesticides,” the urgent need to transition away from chemical-intensive practices grows stronger. Background While this review highlights regulatory gaps in the European Union (EU), the cited scientific […]
Posted in Agriculture, air pollution, Chemical Mixtures, contamination, Disease/Health Effects, Drift, European Union, Pesticide Drift, Pesticide Mixtures, Pesticide Regulation, Pesticide Residues | No Comments »
14
Apr
(Beyond Pesticides, April 14, 2026) A novel study mapping pesticide mixtures and cancer risk, published in Nature Health, “reveals a robust spatial association between environmental pesticide exposure risk and cancer incidence.” The team of international researchers incorporates pesticide risk modeling with Peruvian National Cancer Institute (INEN) registry data to map pesticide-induced cancer clusters in Peru, finding significant associations between pesticide mixtures and cases of carcinogenicity. The study analyzes 31 active ingredients to identify pesticide-associated cancer hotspots, none of which are classified as carcinogenic on their own by international standards. When combined as pesticide mixtures, as experienced in real-world environments, heightened risks and synergistic effects are noted. “Collectively, these findings strongly support a mechanistic [causal] link between pesticide exposure and cancer, challenging assumptions of human non-carcinogenicity derived from reductionist experimental models,” the authors state. “This study redefines the exposome [measure of all environmental, dietary, lifestyle, and social exposures of an individual] as a lineage-conditioned, mechanistically tractable framework and shows how complex pesticide mixtures can contribute to carcinogenic trajectories, with profound and far-reaching implications for global health policy and socio-ecological equity.” Background An extensive body of scientific literature connects individual pesticide active ingredients to a wide array of health and environmental effects […]
Posted in Agriculture, Body Burden, Cancer, Peru, Pesticide Drift, Pesticide Mixtures, Pesticide Residues, synergistic effects | No Comments »