Archive for the 'Glyphosate' Category
15
Aug
(Beyond Pesticides, August 15, 2025) In analyzing the data present in an article in Data in Brief, concerning levels of pesticide biomarkers are present in the urine of adolescents and young adults that are linked to numerous health implications. The biomonitoring data, collected at two time points from participants in a longitudinal cohort study in the agricultural county of Pedro Moncayo, Ecuador, encompasses a total of 23 compounds used as herbicides, insecticides, and fungicides and their associated metabolites (breakdown products), which include organophosphates, pyrethroids, and neonicotinoids. The results highlight the disproportionate risks to a Latin American population that occur as a result of living in areas with heavy chemical-intensive agriculture. âThis article presents urinary pesticide metabolite concentrations for 665 participants in the âStudy of Secondary Exposure to Pesticides among Children, Adolescents, and Adultsâ (ESPINA), which were collected during two follow-up assessments,â the authors describe. The first sampling period from July to October 2016, referred to as Follow-up Year [FUY]-8b, includes 529 of the participants, while the second sampling period from July to September 2022 (FUY-14a) includes 505 of the participants. All participants are within the agricultural community of Pedro Moncayo. As the authors note, âThe ESPINA study aimed to include […]
Posted in 2,4-D, acetamiprid, Agriculture, Biomonitoring, Children, Chlorpyrifos, Clothianidin, Cyfluthrin, cypermethrin, DEET, Deltamethrin, Diazinon, fenpropathrin, Flumethrin, flupyradifurone, Glyphosate, Imidacloprid, International, lambda-cyhalothrin, Malathion, mancozeb, Maneb, Metabolites, neonicotinoids, Occupational Health, organophosphate, Parathion, Permethrin, pyrethroids, Repellent, Sulfoxaflor, Synthetic Pyrethroid, Synthetic Pyrethroids, thiacloprid, Thiamethoxam, tralomethrin | No Comments »
14
Aug
(Beyond Pesticides, August 14, 2025) A review in Clinical and Experimental Obstetrics & Gynecology links various classes of environmental pollutants including pesticides and per- and polyfluoroalkyl substances (PFAS), both of which Beyond Pesticides has extensively covered, to adverse effects on the female reproductive system and common mechanisms of toxicity. These chemicals âdisrupt the hypothalamic-pituitary-gonadal axis (HPG), impair ovarian function, and contribute to reproductive dysfunction through mechanisms such as oxidative stress, hormonal disruption, and epigenetic [gene expression or behavior] modifications,â the authors say. This leads to menstrual irregularities, infertility, and pregnancy complications, as well as increases in the risk of reproductive system disorders such as endometriosis, polycystic ovary syndrome (PCOS), and ovarian cancer, among others. âAdditionally, transgenerational effects mediated by epigenetic modifications, germ cell damage, and placental transfer may adversely affect offspring health, increasing the risk of reproductive dysfunction, neurodevelopmental disorders, metabolic diseases, and cancer,â the researchers explain. This study, integrating recent epidemiological and experimental findings, provides an overview of major chemical classes that threaten womenâs health and highlights the need for immediate action. As the authors point out, female reproductive health is important not only for those who choose to plan for a family but also for the overall well-being […]
Posted in Birth defects, Cancer, contamination, Developmental Disorders, DNA Damage, Endocrine Disruption, Epigenetic, Glyphosate, Infertility, Miscarriage, multi-generational effects, organochlorines, organophosphate, Oxidative Stress, PCOS, Reproductive Health, synergistic effects, Women's Health | No Comments »
08
Aug
(Beyond Pesticides, August 8, 2025) In a study published in Environmental Pollution, researchers have detected eighty pesticides (35 insecticides, 29 fungicides, and 11 herbicides, and metabolites) in the ambient air of a rural region of Spain (Valencia) between 2007 and 2024. Despite these dramatic findings, the authors conclude that there is âno [observable] cancer risk,â âno inhalation risk for adults,â and only one pesticide concentration (the insecticide chlorpyrifos) showing âa potential risk to toddlers.â However, the authors did not conduct an aggregate risk assessment that would typically consider all routes of exposure to the individual pesticides detected, including through water, food, and landscapes. Not considered by the authors are the potential effects of pesticide mixtures and full pesticide product formulations (with all potentially toxic ingredients), also a deficiency in the U.S. Environmental Protection Agency (EPA) registration of pesticides under federal law. Of concern, as well, are other contaminants in pesticide products, including but not limited to per- and polyfluoroalkyl substances (PFAS), heavy metals, plastics (including microplastics), which contribute to chronic diseases and health risks, and adverse effects to ecosystem stability exacerbated by the climate crisis. Background and Methodology âThis work aims to conduct a further study on the situation of […]
Posted in Abamectin, acetamiprid, air pollution, Azoxystrobin, Bendiocarb, Bifenthrin, boscalid, Carbendazim, Carbofuran, Chemicals, Chlorothalonil, Chlorpyrifos, cypermethrin, Deltamethrin, Diazinon, Dichlorvos, Dimethoate, Diuron, Endosulfan, endothall, Ethoprop, fenbuconazole, Fenthion, Fipronil, fludioxonil, Glyphosate, Imidacloprid, lambda-cyhalothrin, Malathion, Methidathion, Permethrin, Pesticide Drift, pirimicarb, Propargite, Pyriproxyfen, spinosad, Thiamethoxam, Trifluralin, Uncategorized, vinclozolin | No Comments »
04
Aug
(Beyond Pesticides, August 4, 2025) Comments on EPA proposal to bring back controversial use of herbicide dicamba due by Friday, August 22, 2025, at 11:59 PM ET. With more than 90 percent of soybeans (also corn and the most common species of cotton) planted in varieties genetically engineered to be herbicide-tolerant, the agrichemical industry and industrial agribusiness are lining up to bring back agricultural spraying of the controversial weed killer dicambaâlinked to crop damage associated with the chemicalâs drifting off the target farms. The courts in 2020 and 2024 vacated EPAâs registration authorizing âover-the-topâ (OTT) spraying of dicamba, leading to these uses being stopped in the 2025 growing season. (See Daily News.)             Genetically engineered crops, widely adopted in 1996 with Monsantoâs glyphosate-tolerant (Roundup Ready) soybean seeds and plants, have been plagued by weed resistance to the weed killers, movement of genetic material, chemical drift, and health and environmental hazards associated with pesticide exposure. Despite the problems and escalating herbicide use in chemical-dependent no-till (no tillage) agriculture, regulators at the U.S. Environmental Protection Agency (EPA) and the U.S. Department of Agriculture (USDA) have facilitated the astronomical growth of a genetically engineered food system. The industry makes the environmental argument that less disturbance […]
Posted in Agriculture, Bayer, Dicamba, Environmental Protection Agency (EPA), Genetic Engineering, Glyphosate, Monsanto, Pesticide Drift, Seeds, Take Action, Uncategorized, US Department of Agriculture (USDA) | 6 Comments »
01
Aug
(Beyond Pesticides, August 1, 2025)Â On June 30, Kyle Kunkler started work as deputy assistant administrator for pesticides in U.S. Environmental Protection Agencyâs (EPA) Office of Chemical Safety and Pollution Prevention. Mr. Kunkler is an experienced agribusiness lobbyist, having come directly from the American Soybean Association, where he was director of government affairs. He joins Nancy Beck, PhD, herself a migrant from the American Chemistry Council. Not coincidentally, a mere three weeks after Mr. Kunklerâs appointment, EPA opened the floodgates to allow use of the controversial herbicide dicamba to flow unrestricted once again through the nationâs ecosystems. Dicamba has been associated with phytotoxic crop/plant damage (leaf damage, stunted growth, or death) and cancer. Three formulations of the herbicide whose registrations had been vacated via litigation will be reinstated by EPA after a public comment period that expires on August 22 at 11:59 PM EDT. Dicamba is manifestly one of the worst ideas the pesticide industry has ever devised, according to many farmers and pesticide safety advocates. Because of resistance to other herbicides, pesticide scientists developed the â[insert pesticide]-readyâ concept in which a crop plant is genetically engineered to resist exposure to a herbicide, âRoundup-Readyâ seeds being the most obvious example, so […]
Posted in 2,4-D, Agriculture, amines, Cancer, Dicamba, Drift, Environmental Protection Agency (EPA), Glyphosate, Herbicides, nitrosamines, Pesticide Regulation, Uncategorized | No Comments »
31
Jul
(Beyond Pesticides, July 31, 2025) A study published in Environmental Advances finds that hundreds of honeybee hives across central and northern Italy are contaminated with various pesticides and their metabolites, including glyphosate and fosetyl. âThere was no significant difference in glyphosate presence between dead/dying and live bees, suggesting chronic exposure rather than acute toxicity. However, higher pesticide concentrations in dead/dying bees indicate potential sublethal effects contributing to colony distress,â according to the authors. This peer-reviewed study builds on the mounting evidence outlined in the literature connecting pesticide residues to nontarget harm to pollinators and other insects and animals that are critical to biodiversity. Background and Methodology âThe primary objectives of this study were to develop and validate a reliable, sensitive method for analyzing polar pesticides [highly soluble in water] in honeybees and to investigate polar pesticides residue levels in honeybees across northern and central Italy,â say the researchers of this study, who conduct research at the Experimental Zooprophylactic Institute of Lombardy and Emilia Romagna âBruno Ubertini”, Experimental Zooprophylactic Institute of Umbria and Marche âTogo Rosatiâ, and Experimental Zooprophylactic Institute of Lazio and Tuscany “M. Aleandri.” 314 honeybee samples were gathered voluntarily from local beekeepers in six regions of northern and […]
Posted in Chemical Mixtures, Chemicals, Environmental Protection Agency (EPA), glufosinate, Glyphosate, International, Persistence, Poisoning, Pollinators, Uncategorized | No Comments »
21
Jul
(Beyond Pesticides, July 21, 2025) Beyond Pesticides is asking every member of the U.S. Representatives to voice their opposition in advance of a vote as early as Tuesday, July 22 on a provision before the House Appropriations Committeeâin the Interior-Environment Appropriations Billâthat shields pesticide companies from lawsuits by those harmed from pesticide product use and limits statesâ authority to regulate pesticides. This is a fight to protect farmers’ and consumers’ right to sue pesticide manufacturers for misbranding products and their failure to warn product users. The language before the Committee is in Section 453 of the bill passed last week by the subcommittee on a straight party-line vote, with Republicans supporting the bill language. Beyond Pesticides is also asking Congress members to remove section 507, which prohibits EPA action on PFAS (per- and polyfluoroalkyl substances), including fluorinated pesticides. Update from July 21, 2025, at 4 PM: ⏰ Representative Chellie Pingree (D-ME-1) moved forward with amendments to strike sections 453 and 507 of the FY26 Interior-Environment Appropriations Bill, which is a provision that provides immunity for pesticide manufacturers from farmer and consumer lawsuits seeking compensation from product harm. Update from July 23, 2025, at 10 AM: The FY26 Interior-Environment Appropriations Bill passed out of […]
Posted in Agriculture, Bayer, Cancer, Chem-China, Environmental Protection Agency (EPA), Failure to Warn, Glyphosate, Litigation, Monsanto, Parkinson's, Preemption, Take Action, Uncategorized | 12 Comments »
18
Jul
(Beyond Pesticides, July 18, 2025) A study in Royal Society Open Science shows intraspecific differences (between individuals of a species) in wild bumblebees (Bombus vosnesenskii) exposed to an herbicide (glyphosate), a fungicide (tebuconazole), and an insecticide (imidacloprid), with gut microbiome health as a factor. âWild pollinator declines are increasingly linked to pesticide exposure, yet it is unclear how intraspecific differences contribute to observed variation in sensitivity, and the role gut microbes play in the sensitivity of wild bees is largely unexplored,â the authors explain. âHere, we investigate site-level differences in survival and microbiome structure of a wild bumble bee exposed to multiple pesticides, both individually and in combination.â In collecting 175 individuals of this wild, foraging species from an alpine meadow, a valley lake shoreline, and a suburban park and exposing them to a diet with individual pesticides and mixtures, the researchers assess the varying lethal and sublethal effects that can occur with pesticide exposure. Between the three sites, the survival differences âemphasize the importance of considering population of origin when studying pesticide toxicity of wild beesâ and highlight how pesticide sensitivity not only varies between species but within individuals of the same species with site-specific impacts. (See previous Daily […]
Posted in Beneficials, Biodiversity, Ecosystem Services, Glyphosate, Imidacloprid, Microbiome, Nevada, Pesticide Mixtures, Pesticide Regulation, Pollinators, synergistic effects, tebuconazole, Wildlife/Endangered Sp. | No Comments »
11
Jul
(Beyond Pesticides, July 11, 2025) Pesticides and antibiotics are linked inextricably in the looming crisis of human and ecosystem health. Both started out as quasi-miraculous solutions to age-old human problems, yet it has been clear that the failures of each present severe challengesâand that they are synergistic because they trigger the same kinds of defensive mechanisms in their targets: insects, fungi, and weeds on the one hand, and microbes on the other. A review of contamination of waterways in India with pesticides and antibiotics, published in Environmental and Geochemical Health, recounts the many threats that arise when these chemicals mix and how their presence in water makes the problems much worse. Â Â Globally, about five million people died in 2019 from infections with antibiotic-resistant microbes. By 2050, according to a World Bank estimate, antibiotic resistance could add $1 trillion to global health care costs and subtract $3.4 trillion from annual global gross domestic product. While the world slowly realizes the urgent need to counter antibiotic resistance, the role of pesticides in generating it has received less political and public attention. But there is no doubt that pesticides are strongly implicated. In fact, the resistance of microbes to antibiotics is no […]
Posted in 2,4-D, Agriculture, Antibiotic Resistance, Antimicrobial, Aquaculture, Dicamba, Endosulfan, Fungicides, Glyphosate, Hydroponics, Uncategorized, Water | No Comments »
02
Jul
(Beyond Pesticides, July 2, 2025) An article in The New Lede, entitled Seeking answers to a cancer crisis in Iowa, researchers question if agriculture is to blame, documents case studies of cancer diagnoses linked to chemical-intensive agriculture. Current national cancer rates, according to the American Cancer Society, show that two million new cancer cases are projected to occur during 2025 in the U.S. Additional research predicts 618,120 cancer deaths this year as well, highlighting a crisis of great concern. A wide body of science links increased cancer risks with exposure to agricultural chemicals, including petrochemical pesticides and synthetic fertilizers. Previous coverage from Beyond Pesticides showcases the disproportionate health risks to farmworkers and their families, as well as those living near agricultural fields, associated with exposure to harmful toxicants. Recent research ties pesticide use to cancer diagnoses among farmer populations through a literature review of clinical trials, as well as epidemiologic, case-control, and experimental studies, from not only the U.S. but Brazil, India, France, Egypt, Columbia, Ecuador, Mexico, Italy, and Spain. (See Daily News here.) Additional risks for children, as reported in a study in GeoHealth, are noted in Nebraska as exposure to agricultural mixtures show statistically significant positive associations with […]
Posted in Agriculture, Cancer, Children, Farmworkers, Glyphosate, Iowa, Leukemia, non-Hodgkin's Lymphoma, PFAS | No Comments »
25
Jun
(Beyond Pesticides, June 25, 2025) A United Kingdom (UK) study, published in May by the Womenâs Environmental Network (Wen) and Pesticide Action Network (PAN) UK, is reporting levels of the herbicide glyphosateâa probable human carcinogen that is also linked to Parkinsonâs diseaseâin tampons at concentrations 40 times higher than the legal drinking water limit. This finding highlights the serious public health threats that result from under-regulated period products, given that 1.8 billion people worldwide menstruate monthly, according to UNICEF.  The report raises fundamental concerns about the harm to womenâs health associated with toxic chemical exposure. For tampon users, the vaginal route of exposure bypasses detoxification with a significantly higher absorption rate than skin. In addition, health concerns extend to ongoing chronic toxic chemical exposures to women worldwide working in cotton production and living in nearby communities. Methodology To investigate whether menstrual products contain harmful pesticide residues and whether current safety standards adequately control the risk of vaginal exposure, study researchers tested 15 boxes of tampons directly bought from UK supermarkets. These boxes were sent to an external laboratory for testing that looks for the presence of glyphosate and its breakdown product amionomethylphosphoric acid (AMPA) in the cotton material used to […]
Posted in aminomethylphosphonic acid (AMPA), endometriosis, Glyphosate, Herbicides, PCOS, Reproductive Health, Uncategorized | 1 Comment »
11
Jun
(Beyond Pesticides, June 11, 2025) Researchers developed a novel tool* in a recent study published in Nature Communications this year that successfully creates a map of the âpesticide-gut microbiota-metabolite network,â identifying âsignificant alterations in gut bacteria metabolism.â While the study authors acknowledge that this is not a complete map, since they selected specific pesticides and bacterial partners, the research adds to the body of peer-reviewed scientific literature that underscores the relationship between pesticide residues and human gut health. Organic farmers, as well as any land steward invested in agroecological practices and soil health, understand that microbial life (both in the body and in the soil) is dangerously undermined by the status quo of chemical-intensive land management. Background and Methodology The researchers leverage mass spectrometry to test metabolite (metabolomics) and lipid (lipidomics) relationships with pesticide residues, as well as an in vivo mouse model. *The map itself is a form of computational biology, which advocates have warned could be a false solution if not accompanied by other proven scientific methods. See here for analysis by the Natural Resources Defense Council on risks of unproven methods such as New Approach Methodologies [NAMs]. All major phylogenetic (âevolutionary relationships among biological entitiesâ) groups are […]
Posted in Chlorpyrifos, cypermethrin, DDT, Diazinon, Dichlorvos, Endosulfan, Glyphosate, Malathion, Metabolites, methoxychlor, Microbiata, Microbiome, Parathion, Permethrin, Uncategorized | No Comments »
30
May
(Beyond Pesticides, May 30, 2025) The Making America Healthy Again (MAHA) Commission report, Make Our Children Healthy Again: Assessment, published on May 23, drew criticism from the pesticide industry and agribusiness allies for pointing to independent science that identifies a range of pesticide-induced health hazards.* The Commission, chaired by Robert F. Kennedy, Jr., Secretary of the Department of Health and Human Services (HHS), is composed of the heads of numerous agencies of the federal government and the White House, from the U.S. Environmental Protection Agency (EPA), the U.S. Department of Agriculture (USDA), and the Office of Management and Budget (OMB), to the Assistant to the President and Deputy Chief of Staff for Policy Stephen Miller. The MAHA Commission was established by Executive Order 14212 on February 13, 2025. Despite extensive citations to the science on pesticide hazards, the report includes a section on âCrop Protection Tools,â in which there is a repetition of chemical industry talking points that pesticide residues in food comply with existing tolerances, thus implying that pesticides in food are safe. (See USDA Pesticide Data Program Continues to Mislead the Public on Pesticide Residue Exposure.) However, overall the reportâs introduction sets a tone that seeks to catalogue […]
Posted in Atrazine, Chemical Mixtures, Chemicals, Children, Children/Schools, Chlorpyrifos, Corporations, Corteva, Environmental Protection Agency (EPA), Farm Bill, Farmworkers, Federal Agencies, Glyphosate, Label Claims, Pesticide Mixtures, Preemption, Uncategorized, United Nations | No Comments »
29
May
(Beyond Pesticides, May 29, 2025) A study, published in Environmental Toxicology and Pharmacology, âinvestigates genotoxic effects on farmers in ParaĂba, Brazil, analyzing buccal mucosa cells [cells from inside the cheek] for DNA and cellular damage,â the authors write. In comparing data from 33 pesticide-exposed agricultural workers to 29 unexposed people in a control group, the researchers report that the âfindings revealed significantly higher frequencies of cellular alterations and DNA damage among exposed farmers relative to the control group, with no significant impact from factors such as smoking, alcohol consumption, or family cancer history.â They continue, âThese results underscore the genotoxic risks linked to prolonged pesticide exposure and highlight the necessity for stricter regulatory measures.â As Beyond Pesticides documents in Disproportionate Pesticide Hazards to Farmworkers and People of Color Documented… Again, farmworkers have been excluded from labor and occupational safety protection laws since their inception. The Occupational Safety and Health Administration (OSHA) defers all policy on pesticide protections to the U.S. Environmental Protection Agency (EPA), which has been widely criticized for providing inadequate worker protection standards. This study focuses on workers in Brazil, but represents issues that impact communities worldwide. âThe agricultural sector plays a pivotal role in Brazilâs economy, encompassing […]
Posted in 2,4-D, Abamectin, Agriculture, chlorfenapyr, Cyfluthrin, cypermethrin, Deltamethrin, Diuron, DNA Damage, Farmworkers, Glyphosate, hexazinone, Imidacloprid, Methamidophos, Methomyl, Occupational Health, Oxidative Stress | No Comments »
28
May
(Beyond Pesticides, May 28, 2025)Â A study in Birth Defects Research bolsters existing evidence that agricultural workers, and specifically Hispanic workers in California, are disproportionately bearing the burden of pesticide exposure. Caroline Cox, formerly of the Center for Environmental Health in Oakland, and Jonathan K. London, PhD of the University of California, Davis, examine how currently-used agricultural pesticides unequally affect communities along racial and ethnic gradients. Ms. Cox is a member of Beyond Pesticidesâ board. Using 2022 data from the California Department of Pesticide Regulation (CDPR) and the U.S. Census Bureau, the researchers analyzed county, census tract, and school district data for the percentage of non-Hispanic White population in each population unit and determined the total agricultural use of commercial formulations of pesticides in the same units. CDPR reporting systemâs granular data, including application locations at a resolution of one square mile, and the specific products, dates, and amounts of pesticides used, allows comparison of the data with demographic records. The results show that Hispanicsâ exposure status is robust, independent of current or past data or âindividual pesticides of public health concern.â Pesticides that harm reproductive health were strikingly concentrated among Hispanic populations. There is abundant evidence of racial and ethnic […]
Posted in 1, 3-dichloropropene, 1-3D, Agriculture, California, chloropicrin, Farmworkers, Glyphosate, Malathion, Paraquat, Sulfur, Uncategorized | No Comments »
21
May
(Beyond Pesticides, May 21, 2025) An assessment of the fire hazards of four herbicide products in Science of The Total Environment finds high fire and toxic gas emission risk, particularly in 2,4-D-based weed killer products. The authors note that âInert [nondisclosed] ingredients significantly influence flammability and toxic gas generation in fires,â and the combustion of these products âreleases hazardous gases and polycyclic aromatic hydrocarbons.â These results highlight the fire hazards associated with herbicides, as well as the emission of hazardous substances into the atmosphere, which can threaten environmental and public health.  The authors summarize: â[T]he aim of this work is to raise awareness of the fire hazards posed by the storage of pesticides and what effect the âinertâ substances in them have. In the past, large fires have occurred around the world, e.g., in Basel (1986), Arkansas (1998), and in Eastern Virginia at the Bayer CropScience plant (2008). It is important to note that in addition to large factories and warehouses, fires can affect small crop protection product stores and local wholesalers.â (See related coverage on the 2023 train derailment, fire, and subsequent release of chemicals here.) The U.S. Fire Administration estimates 344,600 residential building fires nationally, based on […]
Posted in 2,4-D, Glyphosate, Groundwater, Occupational Health, Pesticide Mixtures, Volatile Organic Compounds | 1 Comment »
23
Apr
(Beyond Pesticides, April 23, 2025) Recent reviews of scientific literature, in both Chemosphere and Reports in Public Health, associate Parkinsonâs disease (PD), the second most prevalent neurodegenerative disease globally, with pesticide exposure. âGiven the pervasive nature of pesticide residues in everyday food consumption and inadequate monitoring of their long-term toxicological impacts, the role of pesticide exposure as a modifiable risk factor for neurological disorders, including PD, warrants urgent attention,â the researchers state in the article in Chemosphere. In describing the history of Parkinsonâs and previous research, the authors in Reports in Public Health note that while PD etiology is not fully understood, it is a multifactorial disease. âHereditary factors are present in approximately 10% of diagnosed cases of Parkinsonâs disease, presenting early onset; while the other 90% of cases are categorized as idiopathic or sporadic Parkinsonâs disease, occurring in older individuals and may be associated with exposure to environmental agents,â the researchers say. This disease, first described by English physician James Parkinson, M.D. in 1817, involves neurochemical changes that present as âthe appearance of cardinal motor symptoms, such as bradykinesia, rigidity, postural instability, and rest tremor, which are essential for the clinical diagnosis of the disease,â the researchers note. The […]
Posted in 2,4-D, Atrazine, behavioral and cognitive effects, Brain Effects, Chlorpyrifos, cypermethrin, Dichlorvos, Dieldrin, Environmental Protection Agency (EPA), Glyphosate, Malathion, mancozeb, Maneb, Nervous System Effects, Oxidative Stress, Paraquat, Parkinson's, Pesticide Mixtures, Rotenone | No Comments »
17
Apr
(Beyond Pesticides, April 17, 2025) A literature review in Reproductive Sciences finds glyphosate (GLY) and glyphosate-based herbicides (GBH) impact womenâs reproductive health, adding to the long list of documented harm from this widely used weed killer. The authors note, âConsidering the widespread use of GLY, the controversy regarding its endocrine-disrupting potential and reproductive toxicity, and the innumerable lawsuits filed against Bayer and Monsanto by consumers for morbidities related to Roundup™ exposure, the purpose of this review is to summarize the current literature on the potential adverse effects of GLY and GBHs on the female reproductive tract and discuss possible clinical implications on reproductive health outcomes, including polycystic ovarian syndrome (PCOS), endometriosis, and female fertility.â Glyphosate and aminomethylphosphonic acid (AMPA), the primary metabolite (breakdown product) of GLY, are found throughout the environment in soil and water, as well as in samples of blood, urine, seminal plasma, and breast milk. Studies have detected residues in farmworkers, as well as “in the urine of 60â80% of the general public in the USA, including pregnant women and children.â (See studies here, here, and here.) The ubiquitous use of GLY and GBH, and subsequent persistence, threatens the health and well-being of all. Previous studies have […]
Posted in Agriculture, aminomethylphosphonic acid (AMPA), Bayer, DNA Damage, Endocrine Disruption, endometriosis, Glyphosate, Herbicides, Infertility, Monsanto, Oxidative Stress, PCOS, Reproductive Health, Women's Health | No Comments »
08
Apr
(Beyond Pesticides, April 8, 2025) A comprehensive literature review in Environment & Health analyzes evidence from human biomonitoring, epidemiological studies, and toxicological studies that link adverse effects on womenâs reproductive health, specifically impacting the ovary, to pesticide exposure. In examining the scientific literature, consisting of over 200 studies performed in the last 25 years, the authors find pesticide exposure threatens womenâs health through ovarian dysfunction. âEpidemiological studies have shown that pesticide exposures are associated with early/delayed menarche [first occurrence of menstruation], menstrual cycle disorders, early menopause, long time to pregnancy, polycystic ovary syndrome, primary ovarian insufficiency, infertility, and implantation failure in women,â the researchers state. They continue, âBoth in vivo [in animals] and in vitro [in cells] studies have shown that exposure to pesticides disrupts the estrous cycle, reduces the follicle pool, alters hormone levels, and impairs oocyte [egg] maturation.â These reproductive implications are noted with many different classes of pesticides, such as insecticides, including organochlorine pesticides (OCPs), organophosphates (OPs), pyrethroids, and neonicotinoids, as well as herbicides and fungicides. The authors, however, comment on present research gaps: âMuch of the available epidemiological evidence focuses on legacy insecticides, such as OCPs, and a subset of insecticides that are still in use […]
Posted in acetamiprid, Atrazine, Bifenthrin, Chlorpyrifos, cypermethrin, DDT, Deltamethrin, Diazinon, fenvalerate, Glyphosate, Imidacloprid, Infertility, lambda-cyhalothrin, Lindane, Malathion, mancozeb, Oxidative Stress, PCOS, Permethrin, Reproductive Health, Thiamethoxam, vinclozolin, Women's Health | No Comments »
02
Apr
(Beyond Pesticides, April 2, 2025) In examining prenatal residential proximity of documented pesticide spraying in California to the menstrual cycle characteristics of 273 Latina adolescents, researchers report in the American Journal of Epidemiology a positive association between exposure to the insecticide methomyl and heavy bleeding. Other pesticides appear to influence menstrual symptoms as well. âAdolescentsâ menstrual cycle characteristics can be âvital signsâ of health and impact quality of life,â the authors share. They continue, âTo our knowledge, this is the first study to examine the association between prenatal pesticide exposure and menstrual outcomes in adolescents of any demographic group.â Menstrual cycle characteristics, such as dysmenorrhea (painful or uncomfortable menstrual cramps), irregularity, and heavy menstrual bleeding, can also be indicators of underlying health conditions, including endometriosis, polycystic ovary syndrome (PCOS), thyroid dysfunction, and bleeding disorders. By associating the pesticide exposure of mothers during pregnancy to impacts on their children, the researchers highlight important health risks for women and young girls that are often disregarded. âThe prenatal period is a critical period of reproductive development that may be particularly sensitive to endocrine disruption,â the researchers share. As previously reported by Beyond Pesticides, endocrine-disrupting chemicals are any synthetic or natural compounds that hinder […]
Posted in Acephate, California, Children, Chlorpyrifos, Diazinon, Dimethoate, Endocrine Disruption, endometriosis, Environmental Protection Agency (EPA), Glyphosate, Imidacloprid, Malathion, mancozeb, Maneb, Methomyl, Oxidative Stress, PCOS, Permethrin, Reproductive Health, Women's Health | No Comments »
01
Apr
(Beyond Pesticides, April 1, 2025) With the second largest award of nearly $2.1 billion (see reporting on largest), a jury in Georgia state court on March 21 found the pesticide manufacturer Bayer/Monsanto guilty of causing a manâs non-Hodgkin’s lymphoma after use of the companyâs glyphosate-based weedkiller RoundupTM product. The juryâs award includes $65 million in compensatory and $2 billion in punitive damages, as reported by the Associated Press and Courtroom View Network. This verdict in Barnes v. Monsanto (2025) comes amid a concerted effort by Bayer and other chemical and agribusiness groups to take away the main legal argument, âfailure-to-warn,â for the type of litigation that pesticide exposure victims have commonly used to hold companies accountable. This is happening as Governor Brian Kemp of Georgia considers signing into state law a pesticide immunity bill that will prevent future litigation like this in the state. In a deregulatory environment, the courts and state governments are viewed as critical backstops, given the dismantling of the U.S. Environmental Protection Agencyâs (EPA) regulatory apparatus and extremely limited Congressional oversight. History of Litigation Bayer has lost almost all of the cases filed against it for compensation and punitive damages associated with the plaintiffsâ charge that […]
Posted in Bayer, Failure to Warn, Georgia, Glyphosate, Litigation, Monsanto, non-Hodgkin's Lymphoma, Preemption, Uncategorized | No Comments »
04
Mar
(Beyond Pesticides, March 4, 2025) A study in GeoHealth of pediatric cancers in Nebraska links exposure to agricultural mixtures with the occurrence of these diseases. The authors find statistically significant positive associations between pesticide usage rates and children with cancer, specifically brain and central nervous system (CNS) cancers and leukemia. âOur study is the first to estimate the effect of an agrichemical mixture on the pediatric cancer rate in Nebraska,â the study authors share. âOne significant advantage of our study is that we identified the pesticide consistently applied over 22 years in Nebraska counties and then estimated the overall mixture effect of these pesticides on pediatric cancer.â The elevated effect of pesticide mixtures, a reality that is not evaluated in the U.S. Environmental Protection Agencyâs (EPA) pesticide registration program, was reported in Oecologia (2008), documenting harm to amphibian populations even if the concentration of the individual chemicals is within limits considered acceptable. (See additional coverage here.) There is a wide body of science highlighting the disproportionate risk of adverse health effects in children with pesticide exposure. Their small size and developing organ systems, propensity to crawl and play near the ground, tendency for frequent hand-to-mouth motion, and greater intake of […]
Posted in Cancer, Chemical Mixtures, Children, Dicamba, Environmental Protection Agency (EPA), Glyphosate, Leukemia, Nebraska, Paraquat, synergistic effects | No Comments »
27
Feb
(Beyond Pesticides, February 27, 2025) In analyzing current scientific literature and data on glyphosate-based herbicides (GBHs), a research article in Environmental Sciences Europe finds that glyphosate (GLY) persists in bones before reentering the bloodstream. The mechanisms in which GLY interacts with important cells for development, called hematopoietic stem cells (HSCs), and breaks and rearranges DNA offer a possible explanation for the heightened risk of cancer, specifically blood cancers like non-Hodgkin lymphoma (NHL), myeloma, and leukemia. âExisting data on GLY/GBH metabolism and genotoxicity provide critical insights into how exposures may be contributing to blood cancers,â according to the studyâs author, Charles Benbrook, PhD. Dr. Benbrook continues: âA significant portion of GLY reaching blood moves quickly into bone marrow and then bone, where it can bioaccumulate and persist… Data reviewed herein suggest that a portion of the GLY excreted by most people on a daily basis can be traced to the shedding of calcium-GLY complexes in bone back into the blood supply.â This allows for near-constant contact between glyphosate molecules and hematopoietic stem cells, which are immature cells that can develop into any type of blood cell. Mutations in hematopoietic stem cells can cause blood cancers to emerge. Those at disproportionate risk […]
Posted in Blood Disorders, Body Burden, Cancer, Environmental Protection Agency (EPA), Glyphosate, Leukemia, Metabolites, Monsanto, non-Hodgkin's Lymphoma | No Comments »