Archive for the 'Amyotrophic Lateral Sclerosis (ALS)' Category
22
Nov
(Beyond Pesticides, November 22, 2024) With numerous campaigns at the state and federal level to ban the weed killer paraquat and nearly 6,000 individual lawsuits alleging exposure to it causes Parkinson’s disease (PD), U.S. Senator Cory Booker (D-NJ) and six Senators on October 31 called on the U.S. Environmental Protection Agency (EPA) to ban the chemical. Citing that “[f]armworkers and rural residents are disproportionately exposed to paraquat,” the Senators’ letter to EPA stating that, “Paraquat has been linked to Parkinson’s disease, thyroid cancer, and other health harms such as kidney, liver, and respiratory damage, and reproductive harm, including neurodevelopmental impact on developing fetuses [and] [i]n rural areas, exposure to paraquat and other pesticides during pregnancy can increase the risk of leukemia.” Most of the 6,000 cases against paraquat’s manufacturer, Syngenta, have been consolidated into Multi-District Litigation (MDL) in the U.S. District Court for the Southern District of Illinois. In April, the MDL judge ousted the plaintiffs’ expert witness regarding causality, which resulted in the first five cases ready for trial being tossed out. The defendant sells paraquat globally and is doing everything it can, according to investigative news reports, to discredit any link between paraquat and Parkinson’s, including the use […]
Posted in Chem-China, Environmental Protection Agency (EPA), Nervous System Effects, Parkinson's, Syngenta, Uncategorized | 1 Comment »
11
Nov
(Beyond Pesticides, November 8-11, 2024) On Veterans Day 2024 we honor those who have served the country and allies. In the 117th (2021-2022) U.S. Congress, legislators enacted The Sergeant First Class Heath Robinson Honoring Our Promise to Address Comprehensive Toxics Act of 2022 (PACT Act). Since the law passed just over two years ago, there has been just under 1.3 million total approved claims marking a roughly 75% approval rate for PACT Act related claims, according to Department of Veteran Affairs (VA) accounting of progress between August 10, 2022, and October 12, 2024 through its dedicated bimonthly VA PACT Act Performance Dashboard. The legacy of toxic burn pits (open air areas where the military has burned toxic waste) and other avenues for toxic exposure in military bases oversees, as well as within the United States in Hawai’i (See coverage on asbestos exposure continuously impacting veterans, as reported on by Honolulu Civil Beat) and Puerto Rico (See peer-reviewed literature review here on toxic heavy metals in International Journal of Environmental Research and Public Health), among other areas, comes at a time when the country assesses the ongoing impacts of a history that has been characterized by critics as colonial or imperialist. […]
Posted in Agent Orange, Alternatives/Organics, Cancer, dacthal, Disease/Health Effects, Environmental Protection Agency (EPA), Federal Agencies, Parkinson's, Uncategorized, Veterans Administraton | No Comments »
20
Sep
(Beyond Pesticides, September 20, 2024) As the California State Assembly wrapped up the 2024 legislative session, what was once a proposed ban of the deadly weed killer paraquat (in both agricultural and nonagricultural contexts) was amended and passed as a requirement for California Department of Pesticide Regulation to complete an “expedited review” by January 1, 2029. Paraquat exposure has been linked to Parkinson’s disease. According to reporting by Los Angeles Times, Assemblymember Laura Friedman (D-Burbank) (the original sponsor of the bill) spoke candidly about the prospects for this legislation, “We never thought we’d get a full ban through the Legislature. But we had to push as hard as we could.” Assemblymember Friedman is chair of the bicameral Environmental Caucus and a self-described “steadfast advocate for the environment [and] sustainable communities.” Environmental advocates, public health professionals, and many who have been affected by Parkinson’s disease are calling for the emergency suspension of paraquat, applying the same standard used by the U.S. Environmental Protection Agency (EPA) to ban the herbicide Dacthal/DCPA last month. (See Daily News here.) Context The original legislation responds to significant scientific documentation of the pesticide’s hazards, and an unresponsive regulatory process, as well as previous legislation efforts. In […]
Posted in California, Chemicals, Environmental Protection Agency (EPA), Paraquat, Parkinson's, Uncategorized | No Comments »
03
Sep
(Beyond Pesticides, September 3, 2024) A piercing investigative article in the August 14 New York Times by journalist Greg Donahue reveals the abandonment of a group of brain disease patients in an area of Canada with forestry management for paper products, agriculture, and large amounts of pesticide use, including glyphosate. It illustrates the tension in the relationship between government authorities, regulated industries, and neurologist (physician) on the front lines. The article details the manner in which health officials appeared to manipulate their own investigation of a disease cluster to make it less disruptive to the economy of the Canadian province of New Brunswick. (This Beyond Pesticides analysis, where not otherwise indicated, draws on Mr. Donahue’s article.) New Brunswick has one major town, Moncton, and a large rural area characterized by agriculture and forestry. The province’s agriculture industry is dominated by blueberry production, which occupies the fourth largest amount of agricultural land in New Brunswick. About half the province is forested, with increasing amounts of land devoted to tree plantations intended for paper production. Glyphosate is hands-down the most heavily used pesticide in New Brunswick forestry, and New Brunswick is second only to Ontario in Canada’s total area of glyphosate-treated forest. […]
Posted in Agriculture, Alzheimers's, Forestry, Glyphosate, Herbicides, Lewy Body Disease (LBD), Paraquat, Parkinson's, Uncategorized | No Comments »
20
Aug
(Beyond Pesticides, August 20, 2024) A study published online in the journal Environmental Toxicology and Pharmacology raises continuing concern about residual exposure to organochlorine pesticides (OCPs) and the disruption that they and their metabolites and isomers cause to biological systems. For the most part, OCPs, including dichlorodiphenyltrichloroethane (DDT), are no longer used worldwide, but the legacy of their poisoning and contamination persists. A 2022 article in Environmental Science & Technology cites California condors and marine mammals along California’s coast contaminated with several dozen different halogenated organic compounds (hazardous, often-chlorinated chemicals) related to DDT, chlordane, and other now-banned legacy chemicals. Other research finds DDT in deep ocean sediment and biota. And, more research finds multigeneration effects from DDT exposure with grandmothers’ exposure to DDT increasing granddaughters’ breast cancer and cardiometabolic disorder risk. This study may be the first compilation of research regarding the modes of action for distinct types of organochlorine pesticides (OCPs). The findings raise the significant danger of legacy chemicals that persist for generations and call for a precautionary regulatory standard that is focused on preventing harm and advancing alternative nontoxic practices and products. In tracking the ongoing scientific literature on a broad spectrum of adverse effects daily, Beyond Pesticides […]
Posted in Breakdown Chemicals, Chemicals, Chlordecone, DDT, Disease/Health Effects, Endocrine Disruption, Environmental Protection Agency (EPA), hexachlorobenzene (HCB), hexachlorocyclohexane (HCH), Metabolites, Motor Development Effects, multi-generational effects, National Organic Standards Board/National Organic Program, Nervous System Effects, organochlorines, Oxidative Stress, Pesticide Regulation, Thyroid Disease, Uncategorized | No Comments »
15
Aug
(Beyond Pesticides, August 15, 2024) Adding to research that has linked insecticide disruption of the gut microbial community to the progression of Parkinson’s Disease (PD) in the brain is a recently published study that further examines the gut-brain mechanism at work. A review by neuroscientist Nabanita Ghosh, PhD in Chemical Research in Toxicology—coauthored by Krishnendu Sinha, PhD, molecular toxicologist and applied pharmacologist, and molecular toxicologist Parames C. Sil, PhD—focuses on how pesticide-induced microbial community alterations specifically drive the initiation of PD and the precise mechanism. The study also explores microbiota changes at different stages of PD progression, offering recent findings.    The researchers derive their data from the examination of PD patients, evaluating the “interaction between pesticides and gut bacteria in PD patients, summarizing how pesticides cause imbalances in gut bacteria, the resulting changes, and their overall effects on the PD prognosis.”  The review “looks at how pesticides and gut bacteria separately influence PD development and progression, highlighting the harmful effects of pesticides and changes in gut bacteria.” The team concludes that pesticide exposure is connected to PD onset through “disturbances in gut function and alterations in intestinal microbiota.” However, the “exact role of microbial factors in this connection remains […]
Posted in Brain Effects, Gut Dysbiosis, Microbiata, Microbiome, Paraquat, Parkinson's, Uncategorized | 1 Comment »
05
Jun
(Beyond Pesticides, June 5, 2024) Individuals living near chemical-intensive agricultural environments have heightened risk of Alzheimer’s disease relative to the general population, according to a study published earlier this year in Psychiatry Research. This finding builds on existing peer-reviewed studies that document the relationship between chronic pesticide exposure and elevated risk of neurodegenerative disorders including Alzheimer’s disease, as well as Parkinson’s disease, dementia, multiple sclerosis (MS), and Huntington’s disease. In light of the mountains of scientific evidence, advocates continue to demand for a wholesale transformation of agricultural and land management systems to one based in organic principles in alignment with the U.S. National Organic Program. Study Analysis This study was published online on May 1, 2024 with the full entry to be published in July 2024. The researchers are physicians, health professionals, and professors at the University of Almeria in southern Spain, specifically working in the Health Research Center and the Department of Nursing, Physiotherapy and Medicine. There is also a researcher, Cristofer Ruiz-González, who works at the Torrecárdenas University Hospital also located in Almeria, Spain. Researchers gathered case information from over 40,000 patients between 2000 and 2021 living in demarcated health care districts with high and low levels of […]
Posted in Alzheimers's, California, Disease/Health Effects, Parkinson's, Pesticide Mixtures, Uncategorized | No Comments »
03
May
(Beyond Pesticides, May 3, 2024) Parkinson’s disease (PD) is the second most common neurodegenerative disease in the world after Alzheimer’s. Genetic factors account for only a fraction of PD cases, and for decades scientists have been aware of associations between pesticide exposures and PD. Yet, not everyone exposed to pesticides gets PD. Consequently, neither the genetic nor the environmental hypothesis is fully satisfactory; both may be involved. Thus, there has been great interest in identifying gene variants that affect the risks of PD associated with pesticide exposure. Now a team of University of California at Los Angeles researchers led by neurologist Brent Fogel, MD, PhD has traced a connection between certain gene variants and the occurrence and severity of PD in a cohort of central California PD patients who have had long-term exposure to pesticides. The genes are related to autophagy, the process by which cells organize, degrade, recycle or eject molecules to maintain healthy chemical balance. Autophagy is an essential process throughout the body, including regulation of mitochondria, which are also vital for healthy cellular function. The study supports other research suggesting that autophagy is disturbed in neurodegenerative diseases. As Beyond Pesticides discussed in its April 19 Daily News, PD […]
Posted in arsenic, cacodylic acid, California, Carbamates, Farmworkers, Lewy Body Disease (LBD), Nervous System Effects, organoarsenic, organophosphate, Parkinson's, Uncategorized | No Comments »
19
Apr
(Beyond Pesticides, April 19, 2024) Parkinson’s disease (PD) and certain forms of dementia have been associated with exposure to pesticides, industrial chemicals, and air pollution for decades. But the mechanisms of disease progression have been unclear, and U.S. regulators have been reluctant to recognize the risks. Now neurologist E. Ray Dorsey, MD of the University of Rochester and researchers from the University of Alabama at Birmingham and Aarhus University in Denmark propose a new research paradigm based on tracking how toxicants cause neurodegeneration through inhalation and ingestion pathways. The paradigm, the authors believe, can be used to gain insight into how PD and a form of dementia known as Lewy body disease (LBD) are initiated as many as 50 years before the onset of symptoms. Dorsey and colleagues build on a recent theory that PD and LBD may be two versions of the same basic disease, both involving Lewy bodies in the nervous system. The group’s proposal was published in the Journal of Parkinson’s Disease in April. If its recommended research agenda produces the anticipated empirical support, the new paradigm will demand integration of many interdisciplinary lines of evidence showing that environmental exposures to synthetic chemicals may be the primary cause […]
Posted in Lawns/Landscapes, Lewy Body Disease (LBD), Parkinson's, Uncategorized | No Comments »
18
Apr
(Beyond Pesticides, April 18, 2024) University of Michigan researchers have found a statistically significant relationship between heightened risk of amyotrophic lateral sclerosis (ALS) and household exposure to lawn care products and pesticides. The study results were published earlier this month in Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. The interdisciplinary research team concludes that modifying residential exposure to toxic substances, including pesticides, can play an important role in ALS susceptibility and prognosis. The results build on a substantial body of scientific literature identifying pesticide exposure in various ALS cohort studies. Advocates say that these adverse effects, along with other numerous health and environmental effects, inform their call for the phaseout of toxic pesticide use and the adoption of alternative practices and eco-compatible products. All participants in this study are patients at the University of Michigan Pranger ALS Clinic with Gold Coast ALS diagnosis, which according to a Muscle & Nerve study refers to the identification of two factors: “progressive motor impairment documented by history or repeated clinical assessment” and “the presence of upper and lower motor neuron dysfunction in a least one body region.” All 367 ALS and 255 control patients were tasked with completing a survey in which they self-reported […]
Posted in 2,4-D, Amyotrophic Lateral Sclerosis (ALS), Biomonitoring, Carbaryl, Chlorpyrifos, Disease/Health Effects, Glyphosate, Herbicides, Lawns/Landscapes, Michigan, Pesticide Drift, Pesticide Residues, Poisoning, Uncategorized | No Comments »
16
Apr
(Beyond Pesticides, April 16, 2024) Citing serious health issues associated with its use, including Parkinson’s disease, and inaction by the U.S. Environmental Protection Agency (EPA), the weed killer paraquat would be banned through legislation introduced in the California Assembly (AB 1963). Assemblymember Laura Friedman (D-Burbank), in the Assembly’s leadership, chair of the bicameral Environmental Caucus, and a self-described “steadfast advocate for the environment [and] sustainable communities,” introduced the legislation to phase out and ban the use of paraquat across all uses, including agriculture, by the end of 2025. The introduction of this bill follows a long history of scientific documentation of the pesticide’s hazards, fits and starts in the regulatory process, and previous efforts to ban the herbicide through legislative action. In 2018, U.S. Representative Nydia Velasquez (D-NY) introduced legislation (Protect Against Paraquat Act) to ban paraquat. In a 1986 factsheet, Beyond Pesticides wrote, “In mammals, paraquat attacks the epithelial tissues (the skin, nails, the cornea of the eye, and the linings of the respiratory and gastrointestinal tract). There have also been reports of damage to the heart muscle and to nerves. It is easily absorbed through the skin as well as orally [and through inhalation]. Paraquat causes specific damage […]
Posted in California, Environmental Protection Agency (EPA), Paraquat, Parkinson's, Pesticide Regulation, Uncategorized | 1 Comment »
09
Apr
(Beyond Pesticides, April 9, 2024) The United States Court of Appeals for the Fifth Circuit, in an opinion authored by Circuit Judge Cory T. Wilson, has vacated an action by the U.S. Environmental Protection Agency (EPA) that had ordered the Texas-based manufacturer Inhance Technologies, L.L.C. to stop producing plastic containers that leach toxic per- and polyfluoroalkyl substances (PFAS) into pesticides, household cleaners, condiments, and additional products. EPA has taken action after the agency determined that the PFAS created during the fluorination process “are highly toxic and present unreasonable risks that cannot be prevented other than through prohibition of manufacture.” While the court is not challenging EPA’s authority to determine the hazards associated with PFAS exposure to be unacceptable, on a technicality, it is finding that the agency used the wrong section of the Toxic Substances Control Act (TSCA), Section 5, which the court says is focused on new uses. According to the Court, “The EPA is just not allowed to skirt the framework set by Congress by arbitrarily deeming Inhance’s decades-old fluorination process a “significant new use,” even though EPA’s awareness of the PFAS contamination was “new” to the agency and not disclosed by the manufacturer. Even if EPA were […]
Posted in Cancer, Drinking Water, Environmental Protection Agency (EPA), Inhance Technologies, Liver Damage, National Organic Standards Board/National Organic Program, Nervous System Effects, NOSB National Organic Standards Board, Organic Foods Production Act OFPA, PFAS, Plastic, Regenerative, Respiratory Diseases, Thyroid Disease, Uncategorized, Water | No Comments »
04
Apr
(Beyond Pesticides, April 4, 2024) Researchers at the National Institute of Pediatrics and National Polytechnic Institute found positive associations between pesticide exposure and heightened risk of certain childhood cancers. The finding is derived from a meta-analysis of 174 studies published between 2013 and 2023 and published in the International Journal of Molecular Science. The authors note, “Although [pesticide exposure] association with childhood cancer has not been fully demonstrated, we found that more than 80% of the epidemiological studies show positive associations [with forms of childhood cancer].” Approximately one third of identified studies (roughly 16) find positive relationships between prenatal and postnatal pesticide exposure with heightened risk of leukemia, neuroblastoma, and rare forms of cancer, such as Wilms tumor. For central nervous system (CNS) tumors, half of identified studies (roughly 24) found a positive relationship with pesticide exposure. The researchers call on further research regarding interaction between different pesticides and health impacts on cumulative exposure. The study is broad in scope, identifying various environmental pollutants and their associations with certain childhood cancers (e.g. radon exposure, air pollution, electromagnetic fields, indoor chemicals, and tobacco and alcohol). This Daily News focuses specifically on pesticide exposure. The researchers originally identified 6,172 studies through PubMed, however […]
Posted in Cancer, Leukemia, Metabolites, Nervous System Effects, Oxidative Stress, Uncategorized | No Comments »
29
Feb
(Beyond Pesticides, February 29, 2024) In the face of federal inaction, an Oregon regulation banning the agricultural uses of the highly toxic chlorpyrifos took effect on January 1, 2024. Chlorpyrifos was voluntarily withdrawn from the market in 2000 for most residential uses by its manufacturer, Dow Chemical, and has been the subject of extensive litigation. At that time, the U.S. Environmental Protection Agency (EPA) allowed most agricultural uses to continue. Oregon joins four other states that have acted to ban chlorpyrifos, including Hawai’i, New York, California, and Maryland.  Central to state action are nervous system and brain effects in children, especially farmworker children. Chlorpyrifos is banned in 39 countries, including the European Union (see here for more Beyond Pesticides coverage). State action has become important since the November 2023 decision by the U.S. Court of Appeals for the 8th Circuit, which overturned the EPA rule revoking all food tolerances for chlorpyrifos, an effective ban on chlorpyrifos use. The final EPA rule, issued in August 2021, came in response to a 9th Circuit Court of Appeals ruling that found the agency’s inaction on chlorpyrifos unlawful. The case was filed by Earthjustice, on behalf of public health, labor, and disability organizations. The […]
Posted in Agriculture, Chlorpyrifos, Dow Chemical, Drift, Environmental Justice, Environmental Protection Agency (EPA), Farmworkers, Nervous System Effects, Oregon, Pesticide Regulation, Pesticide Residues, Uncategorized | No Comments »
22
Feb
(Beyond Pesticides, Feb 22, 2024) The Idaho Senate failed to pass SB 1245 last week which would have provided legal protection to pesticide manufacturers from “failure-to-warn” liability. This legal framework has been pivotal not only for plaintiffs, who are typically users of a toxic product, seeking redress from exposure to glyphosate-based herbicide products such as Roundup, but can also potentially extend to any toxic pesticide products. Similar bills have recently been introduced in the Iowa, Florida, and Missouri state legislatures as petrochemical pesticide industry actors such as Bayer face billions of dollars in legal settlements from victims of pesticide injury. While the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) registration process permits the labeling of products with pesticidal claims based on compliance with testing requirements, the state legislation would establish EPA-authorized pesticide labels as definitive evidence that cannot be challenged in a court of law. The Idaho legislation, SB 1245, was introduced in January in the state Senate by Senator Mark Harris, who represents Soda Springs County, which has North America’s largest elemental phosphorus mine (phosphorus is a critical ingredient in developing glyphosate). Proponents of SB 1245 argue, “[This bill] protect[s] companies that produce safe pesticides critical to agriculture in […]
Posted in Bayer, Blood Disorders, Florida, Glyphosate, Idaho, Iowa, Label Claims, Missouri, Nervous System Effects, Uncategorized | 3 Comments »
08
Feb
(Beyond Pesticides, February 8, 2024) A study published in Environmental Research finds an association between adverse neurodevelopment (brain function and development) among infants and exposure to the herbicide glyphosate during pregnancy (gestational). Moreover, neurodevelopment becomes more pronounced at 24 months or two years. The increasing prevalence of neurodevelopmental disorders (NDDs) in the United States has raised concerns about the impact of toxic exposures on child development. Given the disproportionate exposure burden in the U.S., children from marginalized groups and low-income families are more likely to face a variety of harmful threats that can negatively affect childhood development. These disparities are linked to neurodevelopmental disorders. NDDs are defined as conditions related to the functioning of the nervous system and the brain, including attention-deficit/hyperactivity disorder (ADHD), autism, learning difficulties, intellectual disability (cognitive impairment), conduct disorders, cerebral palsy, and challenges related to vision and hearing. Therefore, the study notes, “Given glyphosate’s wide usage, further investigation into the impact of gestational glyphosate exposure on neurodevelopment is warranted.” The study includes mother-child pairs in a Puerto Rican birth cohort called PROTECT-CRECE, which measures urinary glyphosate and aminomethylphosphonic acid (AMPA; a metabolite [breakdown product]) of glyphosate) levels from mother and child for analysis. The study collected samples from the mother up to […]
Posted in behavioral and cognitive effects, Children, Glyphosate, Nervous System Effects, Women's Health | No Comments »
05
Feb
(Beyond Pesticides, February 5, 2024) Public Comment Period Ends February 26, 2024. The U.S. Environmental Protection Agency (EPA) never completed protocol for testing pesticides that disrupt the fundamental functioning of organisms, including humans, causing a range of chronic adverse health effects that defy the common misconception that dose makes the poison (“a little bit won’t hurt you”)—when, in fact, minuscule doses (exposure) wreak havoc with biological systems. After a nearly two decade defiance of a federal mandate to institute pesticide registration requirements for endocrine disruptors, EPA has now opened a public comment period ending February 26, 2024 and advocates are criticizing the agency’s proposed evaluation as too narrow. A detailed examination of EPA’s proposal can be found in draft comments by Beyond Pesticides. Endocrine disruption as a phenomenon affecting humans and other species has been critically reviewed by many authors. Endocrine disruptors are chemicals that can, even at extremely low exposure levels, disrupt normal hormonal (endocrine) function. Such endocrine disrupting compounds (EDC) include many pesticides, exposures to which have been linked to infertility and other reproductive disorders, diabetes, cardiovascular disease, obesity, and early puberty, as well as attention deficit hyperactivity disorder (ADHD), Parkinson’s, Alzheimer’s, and childhood and adult cancers. EPA […]
Posted in ADHD, Alzheimers's, Endocrine Disruption, Environmental Protection Agency (EPA), Infertility, Learning Disabilities, Parkinson's, Reproductive Health, Take Action, Uncategorized | No Comments »
01
Feb
(Beyond Pesticides, February 1, 2024) A study published in Science of The Total Environment finds an insecticide ban would be economically beneficial in preventing Parkinson’s disease (PD). Despite differing pesticide exposure scenarios, PD risk lowers without pesticide exposure, especially insecticides that elicit neurotoxicity. In fact, a study published in 2023 notes high exposure to household pesticides, which are primarily insecticides, increases the risk of developing Parkinson’s disease (PD) two-fold. There is a multitude of epidemiologic research on Parkinson’s disease demonstrating several risk factors, including specific genetic mutations and external/environmental triggers (e.g., pesticide use, pollutant exposure, etc.). However, several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the widespread commercialized use of household pesticides among the general population, few epidemiologic studies examine the influence household pesticides, mainly insecticides or disinfectants, have on the risk of PD. Additionally, many studies demonstrate the association between PD onset and occupational (work-related) pesticide exposure patterns. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans […]
Posted in Acephate, Carbaryl, Dimethoate, Malathion, Methomyl, Naled, Parkinson's | No Comments »
04
Jan
(Beyond Pesticides, January 4, 2024) A review published in the Journal of Neurosciences in Rural Practice finds an association between farmers’ pesticide exposure and cognitive impairment. Specifically, farmers suffer from attention deficit, lack of information processing, non-comprehension of verbal cues, slow processing speed, memory loss, sluggishness, speech difficulties, and impaired motor function. Additionally, the risk of adverse effects from exposure increases with time spent around pesticides, like in other occupational (work-related) settings. Although pesticide exposure may not be the only factor involved in cognitive impairment, exposure can work synergistically (together) with other factors, triggering neurotoxicity. Pesticides play various roles in causing or exacerbating adverse health outcomes like neurotoxic effects and chemical damage to the brain. Numerous pesticides impair neurological function, especially for chronically exposed individuals (e.g., farmworkers) or during critical windows of vulnerability and development (e.g., childhood, pregnancy). Mounting evidence over the past years shows that chronic exposure to sublethal (low) levels of pesticides adversely affects the central nervous system (CNS) and neural receptors, such as connections between nerves, the brain, enzymes, and DNA. Specifically, researchers identify agricultural chemical exposure as a cause of many adverse CNS impacts and neurological diseases, including Alzheimer’s, amyotrophic lateral sclerosis (ALS), and Parkinson’s disease. The researchers reviewed scientific articles published in […]
Posted in behavioral and cognitive effects, Brain Effects, Chemicals, Developmental Disorders, Motor neuron disease, Nervous System Effects, Occupational Health, organophosphate, synergistic effects | No Comments »
02
Jan
(Beyond Pesticides, January 2, 2024) [photo credit: Alessandro Marongui, Bhopal Medical Appeal, Bhopal, 2009] The new year begins with numerous critical decisions before the U.S. Environmental Protection Agency (EPA) and its Office of Pesticide Programs, along with other federal agencies and the U.S. Congress, that determine whether the agency will continue to erode its leadership position in meeting the existential crises that threaten health, biodiversity, and climate. Given these crises, EPA under its current authority could take the action necessary to advance a transition away from the use of petrochemical pesticides, since under the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) the hazards associated with pesticides are “unreasonable”—given the availability and viability of organic systems that do not utilize toxic pesticides. As EPA fails to meet the catastrophic environmental and health challenges of the day, communities and states across the U.S. are increasingly exercising their authority to restrict pesticides more stringently than the federal government. FIFRA, as affirmed by the U.S. Supreme Court in Wisconsin Public Intervenor v. Mortier (1991), does not prohibit or preempt local municipalities from adopting more stringent pesticide restrictions throughout their jurisdictions than the federal government. The U.S. Congress over the next several weeks will continue […]
Posted in Aldicarb, carbamate, citrus greening--Huanglongbing (HLB), Environmental Protection Agency (EPA), International, Metam Sodium, Nervous System Effects, Uncategorized | No Comments »
28
Nov
With the elevated adverse impacts associated with pesticides and reproductive health, the Pregnant Workers Fairness Act (PWFA) law may be used to improve protections for farmworkers and other high-risk employees.
Posted in ADHD, Alzheimers's, behavioral and cognitive effects, Birth defects, Body Burden, Brain Effects, California, Chemicals, Children, Developmental Disorders, Disease/Health Effects, Environmental Justice, Farmworkers, Leukemia, Miscarriage, Motor Development Effects, Nervous System Effects, Occupational Health, Poisoning, Reproductive Health, Thyroid Disease, Uncategorized | No Comments »
14
Nov
(Beyond Pesticides, November 14, 2023) One of the Environmental Protection Agency’s (EPA) strongest tools for avoiding responsibility is delay—a tactic that kept cancellation of the neurotoxic pesticide chlorpyrifos at bay for 21 years—until May 2021, when a three-judge panel of the Ninth Circuit Court of Appeals, responded to a petition filed in 2007 by the Natural Resources Defense Council, Pesticide Action Network, and numerous other groups. The Ninth Circuit ordered the agency to quit lollygagging and acknowledge chlorpyrifos’s threat to human health, something the agency had acknowledged already. The Ninth Circuit instructed EPA to either revoke the “safe” tolerances the agency had set for chlorpyrifos’s residue in various foods or demonstrate that they are actually safe. Finally capitulating, EPA issued a final rule in August 2021 revoking all food tolerances for the neurotoxicant. Tell your governor and mayor to adopt policies that support organic land management. This looked like progress until February 2022, when a different set of petitioners—pesticide companies, U.S. farmer groups, and other countries’ agricultural interests—filed an action in the Eighth Circuit Court of Appeals. On November 3 of this year, a three-judge panel of the Eighth Circuit reversed EPA’s decision, thereby neutralizing the Ninth Circuit’s opinion. Chlorpyrifos, […]
Posted in Agriculture, Brain Effects, Chlorpyrifos, Environmental Protection Agency (EPA), Litigation, Nervous System Effects, Uncategorized | No Comments »
13
Nov
(Beyond Pesticides, November 13, 2023) The news of a federal Appeals Court’s reversal of a U.S. Environmental Protection Agency (EPA) decision in early November calls into question the value of the basic structures, processes, and authorities of pesticide law that the public has been told are protective of health and the environment. After decades of review and litigation, this reversal, especially on a highly neurotoxic insecticide like chlorpyrifos, identifies a fundamentally flawed system that does not protect the health of people, in this case, children’s brains. >>Tell your governor and mayor to adopt policies that support organic land management. It was EPA’s finding that chlorpyrifos was destructive of the nervous system, particularly in children, and the functioning of the brain that led to an EPA-negotiated chemical company (Corteva/Dow Chemical) settlement in 1999 (took effect in 2000) that removed residential uses of chlorpyrifos from the market. The 2020 EPA decision, 21 years later, to stop agricultural uses followed another Appeals Court decision, departing from the agency’s usually long drawn-out negotiations that ultimately compromise health and the environment. EPA banned agricultural uses of chlorpyrifos in 2016 in the Obama Administration, but the decision was reversed by the Trump Administration in 2017. Because […]
Posted in Agriculture, Alternatives/Organics, Brain Effects, Children, Chlorpyrifos, Dow Chemical, Environmental Protection Agency (EPA), Litigation, Nervous System Effects, Take Action, Uncategorized | No Comments »