[X] CLOSEMAIN MENU

  • Archives

  • Categories

    • air pollution (8)
    • Announcements (600)
    • Antibiotic Resistance (39)
    • Antimicrobial (17)
    • Aquaculture (30)
    • Aquatic Organisms (33)
    • Bats (7)
    • Beneficials (51)
    • Biofuels (6)
    • Biological Control (34)
    • Biomonitoring (38)
    • Birds (25)
    • btomsfiolone (1)
    • Bug Bombs (2)
    • Canada (10)
    • Cannabis (29)
    • Centers for Disease Control and Prevention (CDC) (9)
    • Chemical Mixtures (3)
    • Children (110)
    • Children/Schools (240)
    • cicadas (1)
    • Climate (30)
    • Climate Change (84)
    • Clover (1)
    • compost (5)
    • Congress (17)
    • contamination (152)
    • deethylatrazine (1)
    • Disinfectants & Sanitizers (18)
    • Drift (13)
    • Drinking Water (15)
    • Ecosystem Services (12)
    • Emergency Exemption (3)
    • Environmental Justice (163)
    • Environmental Protection Agency (EPA) (506)
    • Events (88)
    • Farm Bill (18)
    • Farmworkers (193)
    • Forestry (5)
    • Fracking (4)
    • Fungal Resistance (6)
    • Fungicides (24)
    • Goats (2)
    • Golf (15)
    • Greenhouse (1)
    • Groundwater (14)
    • Health care (32)
    • Herbicides (36)
    • Holidays (37)
    • Household Use (9)
    • Indigenous People (6)
    • Indoor Air Quality (5)
    • Infectious Disease (4)
    • Integrated and Organic Pest Management (70)
    • Invasive Species (35)
    • Label Claims (49)
    • Lawns/Landscapes (248)
    • Litigation (340)
    • Livestock (9)
    • men’s health (1)
    • metabolic syndrome (3)
    • Metabolites (4)
    • Microbiata (20)
    • Microbiome (26)
    • molluscicide (1)
    • Nanosilver (2)
    • Nanotechnology (54)
    • National Politics (388)
    • Native Americans (3)
    • Occupational Health (15)
    • Oceans (9)
    • Office of Inspector General (2)
    • perennial crops (1)
    • Pesticide Drift (161)
    • Pesticide Efficacy (9)
    • Pesticide Mixtures (8)
    • Pesticide Regulation (774)
    • Pesticide Residues (181)
    • Pets (36)
    • Plant Incorporated Protectants (1)
    • Plastic (7)
    • Poisoning (19)
    • Preemption (41)
    • President-elect Transition (2)
    • Repellent (4)
    • Resistance (117)
    • Rights-of-Way (1)
    • Rodenticide (33)
    • Seasonal (3)
    • Seeds (6)
    • soil health (15)
    • Superfund (3)
    • synergistic effects (18)
    • Synthetic Pyrethroids (16)
    • Synthetic Turf (3)
    • Take Action (585)
    • Textile/Apparel/Fashion Industry (1)
    • Toxic Waste (11)
    • Volatile Organic Compounds (1)
    • Women’s Health (25)
    • Wood Preservatives (35)
    • World Health Organization (10)
    • Year in Review (2)
  • Most Viewed Posts

Daily News Blog

Archive for the 'Amyotrophic Lateral Sclerosis (ALS)' Category


23
Mar

Death Tied to 1,3-D (Telone) Fumigant Highlights Sensitivity of the Brain to Pesticide Exposure

(Beyond Pesticides, March 23, 2023) A case report article published in Frontier in Public Health confirms one of the first reported deaths from inhalation of the fumigant 1,3-dichloropropene (1,3-D or Telone) during work, resulting in acute renal (kidney) failure, hyperkalemia (high potassium levels in the blood), and brain edema (swelling). 1,3-D is a highly toxic fumigant used on a variety of crops, but primarily on potatoes, tobacco, strawberries, peanuts, and tomatoes to manage unwanted nematodes in soils. The chlorine-containing compound used in a greenhouse space entered the body of a 50-year-old man in China, being absorbed through the respiratory tract. Despite dilution from his wife, the compound was still strong enough to cause harm to human health. Without proper ventilation and personal protective equipment, wearing merely a surgical mask did not adequately defend against exposure to 1,3-D. This case represents the broader issue of how toxic chemical compounds can enter the body, causing physiological damage. Specifically, pesticides can increase the permeability (absorptiveness) of the blood-brain barrier that filters various molecules entering the brain from the circulatory system. However, the permeation of pesticide molecules elevates the expression and accumulation of soluble proteins in the brain involved in neuroinflammation, which plays a critical role in […]

Share

14
Mar

Implications for Human Health: Work-Related Pesticide Exposure Increases Sleep Disorder Risk

(Beyond Pesticides, March 14, 2023) A study published in Environmental Research and Public Health finds occupational pesticide exposure increases the risk of sleep disorders among farmworkers and pesticide applicators. Specifically, many pesticides, like organophosphates (OPs), are detrimental to neurological function through inhibition of the enzyme acetylcholinesterase (AChE) responsible for ending a neurotransmission event after relaying the necessary information. Without an end to neurotransmission events, individuals experience a buildup of acetylcholine, resulting in convulsions, headaches, weakness, impacts on bodily senses, and other cognitive/mental changes. In addition to illnesses from chemical exposure, inadequate sleep has links to several chronic diseases like type 2 diabetes, cardiovascular disease, obesity, and depression. Therefore, given research links to sleep-related disorders and bodily functions, including endocrine, metabolic, neurological, and cognitive disorders, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The study notes, “The study’s findings can be used to create strategies for addressing mental health issues and promoting mental health and quality of life.” Researchers assess the sleep patterns among individuals living in southeast Spain, near the coast of Almeria, where chemical-intensive agriculture from greenhouses is prevalent. Of the 380 participants in the study, 189 were […]

Share

09
Mar

Prenatal Pesticide Exposure Threatens Children’s Language Development at 18 Months after Birth, Study Finds

(Beyond Pesticides, March 9, 2023) A study published in Environmental Research finds exposure to organophosphate (OP) compounds during pregnancy, or prenatal OP exposure can cause shortfalls in language development abilities at 18 months, stifling preschool-age language expression. Additionally, a timely and co-occurring study published in Environmental International confirms similar results, highlighting that chlorpyrifos (an organophosphate) impedes neurological and psychological development, including language communication and all motor skills of offspring at 12 and 18 months old. Prenatal development is one of the most vulnerable periods of exposure, as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. Given research links to pesticide exposure and neurological and cognitive development, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The Environmental Research authors note, “The etiology [cause] of language development is complex, and this work further highlights the importance of the prenatal environment as a mechanism of influence that are associated with deficits in early language acquisition and ability, which could signal increased behavioral problems and academic difficulties in later childhood that extend […]

Share

19
Jan

Neonicotinoid Insecticides Adversely Affect Nervous System Health, According to Study

(Beyond Pesticides, January 19, 2023) Research published in Environmental Health Perspectives finds the presence of nine various neonicotinoids (neonics) and six neonic metabolites within human cerebrospinal fluid (CSF). CSF is an essential part of the central nervous system (CNS), especially for CNS development. Specific chemical biomarkers (measurable indicators of biological state), like pesticides, found in CSF are useful for diagnosing and evaluating numerous neurological diseases. The nervous system is an integral part of the human body and includes the brain, spinal cord, a vast network of nerves and neurons, all of which are responsible for many of our bodily functions—from sensed to movement. However, mounting evidence over the past years shows that chronic exposure to sublethal (low) levels of pesticides can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. The impacts of pesticides on the nervous system, including the brain, are hazardous, especially for chronically exposed individuals (e.g., farmworkers) or during critical windows of vulnerability and development (e.g., childhood, pregnancy). Researchers identify the role agricultural chemicals play in CNS impacts causing neurological diseases, like amyotrophic lateral sclerosis (ALS) and Parkinson’s disease, dementia-like diseases such as Alzheimer’s, and other effects on cognitive function. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood […]

Share

12
Jan

Pesticides Not Only Linked to Parkinson’s Disease Development, But Accelerating Disease Symptoms

(Beyond Pesticides, January 12, 2023) Exposure to certain pesticides among individuals diagnosed with Parkinson’s disease (PD) can increase the risk of symptom progression. According to a study published in Science of the Total Environment, nearly 20 percent of pesticides associated with the onset of PD also increase the risk of faster decline in motor and non-motor function. Several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Past studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the association between PD onset via pesticide exposure patterns, few epidemiologic studies examine the influence pesticides have on worsening motor and non-motor symptoms in PD. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While […]

Share

09
Jan

Calling for Reform of Pesticide Regulation to Address Health, Biodiversity, and Climate Crises

(Beyond Pesticides, January 9, 2023) The Biden EPA still needs a new vision in order to meet the existential crises in public health, climate change, and biodiversity. The Trump Environmental Protection Agency (EPA) reversed in four years much of the progress made by the EPA in decades. Despite a broad new perspective embodied in President Biden’s Executive Memorandum (EM) Modernizing Regulatory Review issued on his first day in office, the Biden EPA has not adopted a new direction for regulating pesticides. Tell President Biden, EPA, and Congress to adopt a new direction for pesticide regulation. Immediately following his inauguration, President Joe Biden issued the EM, which directs the heads of all executive departments and agencies to produce recommendations for improving and modernizing regulatory review, with a goal of promoting public health and safety, economic growth, social welfare, racial justice, environmental stewardship, human dignity, equity, and the interests of future generations. This EM could reverse the historical trend of status-quo regulatory reviews required by the White House Office of Management and Budget (OMB) that typically support vested economic interests of polluters (e.g., petroleum-based pesticide and fertilizer manufacturers). The President’s EM sets the stage for the adoption of agency policy across government to […]

Share

03
Jan

Hazardous Fumigant in Food Production Harmful to Farmworkers, Groups Call for Ban

(Beyond Pesticides, January 3, 2023) The California Department of Pesticide Regulation (DPR) announced new rules that remove existing limits on the use of 1,3-dichloropropene (1,3-D or Telone), allowing Californians to breathe much more 1,3-D than state toxicologists in the Office of Environmental Health Hazard Assessment (OEHHA) say is safe and highlighting the dangers to which farmworkers are routinely exposed. It is outrageous that the state of California and the U.S. Environmental Protection Agency (EPA) would allow farmworkers—whose labor was judged “essential” during the pandemic—to be routinely exposed to highly toxic pesticides, which could be replaced by organic practices. While the state of California describes its action as increasing protection, advocates point to continued use, unacceptable harm, and the availability of alternative organic agricultural production methods that eliminate the use of 1,3-D. Since over a third of the country’s vegetables and three-quarters of the country’s fruits and nuts are grown in California, most people who buy their food in a grocery store have a stake in how food is grown in the state and the impact that it has on those who live and work there. Tell the state of California, U.S. EPA, an the U.S. Congress to cancel the registration […]

Share

19
Oct

Over a Decade and Countless Children Poisoned, EPA Bans Hazardous Flea Collar Products

(Beyond Pesticides, October 19, 2022) Pet flea collars containing the insecticide tetrachlorvinphos (TCVP) are set to be banned by the U.S. Environmental Protection Agency, according to the agency’s long overdue response to a petition from the Natural Resources Defense Council (NRDC). The highly toxic pesticide has not been used on crops since 1987, yet was permitted for decades in flea collars where children could be intimately exposed to the chemical while petting and playing with the family pet. The decade-long process of bringing use of these products to an end exposes the failures of the U.S. pesticide regulatory system, and how EPA’s weak and flawed decisions that infect the marketplace with severe consequences. One may ask: How many veterinarians prescribed these dangerous flea collars to pet owners, assuming that EPA has properly assessed exposure risks to their human owners? Advocates concerned about EPA’s ongoing propensity to defer to the pesticide industry are urging an overhaul of the regulatory process and a reorientation toward toxic pesticide elimination and the adoption of organic in order to address serious health and environmental threats. NRDC originally filed its petition to ban all uses of TCVP in 2009. The petition noted that the agency completely […]

Share

05
Oct

Exposure to Widely Used Bug Sprays Linked to Rheumatoid Arthritis

(Beyond Pesticides, October 5, 2022) Exposure to widely used synthetic pyrethroids, present in many mosquito adulticides and household insecticides like RAID, is associated with a diagnosis of rheumatoid arthritis, according to research published in Environmental Science and Pollution Research. This is the latest pesticide-induced disease associated with this dangerous class of chemicals – a harm to individual Americans that the U.S. Environmental Protection Agency (EPA) is not considering when it registers pesticides. To remedy the major deficiencies in EPA’s reviews, and protect residents from chronic disease, more and more communities are transitioning to safer, organic pest management practices that do not require pyrethroids and other toxic synthetic pesticides. Rheumatoid arthritis (RA) is an autoimmune disease that causes systemic inflammation throughout the body, resulting in progressive damage to an individual’s joints. In the United States, roughly 1.3 million adults suffer from RA, accounting for nearly 1% of the adult population. Health care costs associated with the disease reach nearly $20 billion annually. To better understand the etiology behind the disease, an international team of researchers from China, Illinois, and Missouri analyzed data from the 2007-2014 National Health and Nutrition Examination Survey (NHANES), a long-running program that began in the early 1960s […]

Share

30
Aug

New Evidence Shows Roundup Damages the Nervous System

(Beyond Pesticides, August 30, 2022) Minuscule amounts of the weed killer Roundup and its active ingredient glyphosate can result in damage to the nervous system, finds research led by scientists at Florida Atlantic University, published in Scientific Reports. As hundreds of millions of pounds of glyphosate continue to be sprayed on hundreds of millions of acres of land throughout the United States each year, recent data indicate that four out of five U.S. children and adults contain detectable levels of glyphosate in their bodies. The pesticide industry and its paid supporters tell Americans that although contamination is widespread, the levels found in humans are not cause for concern. This latest research significantly undermines that specious argument, finding impacts on critical nervous system processes at levels 300 times less than the lowest suggested amount on the Roundup label. “It is concerning how little we understand about the impact of glyphosate on the nervous system,” said Akshay S. Naraine, MSc., coauthor and a PhD student at Florida Atlantic University. “More evidence is mounting for how prevalent exposure to glyphosate is, so this work hopefully pushes other researchers to expand on these findings and solidify where our concerns should be.”  To investigate the […]

Share

24
Aug

Researchers Determine Mechanism of DDT Link to Alzheimer’s, Informing Potential Treatments

(Beyond Pesticides, August 24, 2022) New research is helping the medical community understand the mechanism through which exposure to the banned insecticide DDT increases risk of Alzheimer’s disease. Published in the journal Environmental Health Perspectives, a team of researchers from Florida International University and Rutgers used multiple models to demonstrate the effects of DDT on the production of toxic proteins in the brain. The constant stream of new health risks regarding a chemical banned decades ago underlines the importance of a precautionary approach to pesticide regulation, particularly as red flags are already being raised about the connection between widely used weed killers like glyphosate and neurodegenerative diseases like Alzheimer’s. “The vast majority of research on the disease has been on genetics — and genetics are very important — but the genes that actually cause the disease are very rare,” says study coauthor Jason Richardson, PhD of Florida International University. “Environmental risk factors like exposure to DDT are modifiable. So, if we understand how DDT affects the brain, then perhaps we could target those mechanisms and help the people who have been highly exposed.” Previous research from Dr. Richardson found that DDT exposure increased risk of Alzheimer’s by four times. Scientists […]

Share

04
Aug

Glyphosate Weed Killer Crosses Blood-Brain Barrier, Linked to Alzheimer’s and Other Neurodegenerative Diseases

(Beyond Pesticides, August 4, 2022) An Arizona State University (ASU) study shows that the popular herbicide glyphosate can infiltrate the brain through the blood (blood-brain barrier), increasing neurological disease risk. The blood-brain barrier filters various molecules entering the brain from the circulatory system. However, the permeation of glyphosate molecules elevates the expression of TNFα and the accumulation of soluble beta-amyloid (Aβ) proteins in the brain and has associations with immune, inflammatory, and neurodegenerative diseases like Alzheimer’s disease (AD). More than 6 million people in the U.S. are living with Alzheimer’s, and cases are expected to double by 2050. Although Alzheimer’s research has focused heavily on finding genetic causes of the disease, fewer than half of cases are genetic. Thus, researchers are now evaluating how environmental contaminants may increase disease risk. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood and urine samples and can increase neurotoxicity risk when crossing the brain barrier. Therefore, studies like this highlight the importance of understanding how chemical accumulation in the body can impact long-term health and disease prognosis. The study notes, “Brain glyphosate correlates with increased TNFα levels, suggesting that exposure to this herbicide may trigger neuroinflammation in the brain, which may […]

Share

30
Jun

Common Fungicide Again Linked to Parkinson’s Disease with Molecular Disruption

(Beyond Pesticides, June 30, 2022) A study by Zhongnan University and Shandong University in China finds that the broad-spectrum fungicide maneb increases Parkinson’s disease (PD) risk and development through alterations in protein and metabolite pathways, resulting in neurotoxicity. Several studies find exposure to chemical toxicants, like pesticides, have neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, this study suggests neurological damage from oxidative stress, cell dysfunction, and synapses impairment, among others, increases the incidence of PD subsequent to pesticide exposure. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While only 10 to 15 percent of PD cases are genetic, PD is quickly becoming the world’s fastest-growing brain disease. Therefore, research like this highlights the need to examine molecular mechanisms involved in altering chemical […]

Share

26
May

Neurotoxic Pesticides Disrupt Gut Function Linked to Parkinson’s Disease Development

(Beyond Pesticides, May 26, 2022) A study published in The International Journal of Biochemistry & Cell Biology finds environmental exposure to neurotoxic pesticides increases Parkinson’s Disease (PD) risk through gastrointestinal (GI) disruption. Research finds exposure to chemical toxicants, like pesticides, can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, this study suggests environmental pesticide exposure disrupts GI cells responsible for supporting the autonomic nervous system. Enteric glial cells (EGCs) are GI cells that play a critical role in the functional changes that accompany GI dysfunction, as this dysfunction is one of the earliest symptoms indicating the onset of PD. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses each year. The disease affects 50% more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Identifying early biomarkers of PD, such as pesticide-mediated toxicity on GI cells, is crucially important as symptoms intensify overtime, with no current cure for this fatal disease. While only […]

Share

23
May

Broadscale Devastating Ecological and Health Effects Associated with Herbicide Indaziflam; Ask To Go Organic

(Beyond Pesticides, May 23, 2022)  The climate change-induced increase in wildfire frequency and intensity has lent new urgency to efforts to manage so-called “invasive” plants. Unfortunately, the herbicide-based approach favored by many is both counterproductive and hazardous. It must be replaced by an organic system, incorporating biological control agents like goats and establishing a more resilient ecology.    Tell your county/city officials to replace herbicides with organic vegetation management. Tell EPA and Congress that herbicides must be evaluated in the context of the availability of organic systems. Use of the herbicide indaziflam is an example of the ineffectiveness of management based on herbicides. While indaziflam is considered a “selective” herbicide, it actually kills and prevents germination of a wide range of broad-leaved plants and grasses and comes close to being a soil sterilant. The action on seedlings is long-lasting, thus inhibiting the growth and establishment of a resilient plant community that is resistant to invasion. Given its persistence and nonselective action and the extent of the damage it causes to native soil seed banks and plant biodiversity, indaziflam could contribute to the eventual ecological collapse of ecosystems where it’s applied, similar to the cascading impacts of the systemic insecticides, fipronil and […]

Share

15
Apr

Beyond Pesticides Makes Science-based Case that It Is Imperative to Phase Out Pesticides in a Decade

The organic solutions to problems highlighted in the latest issue of Pesticides and You—based on the importance of healthy ecosystems and public health protection—are within reach, and the data creates an imperative for action now that phases out pesticides within a decade, while ensuring food productivity, resilient land management, and safe food, air, and water. (Beyond Pesticides, April 15, 2022) The current issue of Pesticides and You, RETROSPECTIVE 2021: A Call to Urgent Action, is a look at a year of science, policy, and advocacy that informs both the existential problems that the U.S. and the world are facing due to toxic pesticide dependency, and solutions that can be adopted now. The information in this issue captures the body of science that empowers action at the local, state, and federal level, and provides a framework for challenging toxic pesticide use and putting alternatives in place. The issue finds that 2021 was a pivotal year in both defining the problem and advancing the solution. This year in review is divided into nine sections that provide an accounting of scientific findings documenting serious pesticide-induced health and environmental effects, disproportionate risk to people of color and those with preexisting conditions, regulatory failures, at the same time […]

Share

11
Mar

Despite Past Findings of Insecticide’s Threat to 1,284 Species, EPA Reverses and Allows Continued Use

(Beyond Pesticides, March 11, 2022) With a history of unenforceable and impractical pesticide label restrictions resulting in U.S. Environmental Protection Agency (EPA) findings of ludicrously small or no risk, the agency is at it again with its latest announcement that allows the continued use of the deadly organophosphate insecticide malathion. This just the latest example of what advocates see as an irresponsible federal agency falling far short, as the nation and world sit on the brink of biodiversity collapse and deadly pesticide-induced diseases.   In a head-spinning development, the U.S. Fish and Wildlife Service (FWS) announced on March 8 its final Biological Opinion (BiOp) on malathion, which opinion claims that the commonly used insecticide poses no extinction risk to any protected animal or plant. The FWS review and BiOp are part of EPA’s evaluation of whether malathion — an organophosphate insecticide that causes serious damage to many organisms — should retain its registration. The Executive Summary of the BiOp concludes: “Our findings suggest that no proposed species or candidate species would experience species-level effects from the action [i.e., registration and thus, permitted use of malathion], and, therefore, are not likely to be jeopardized. We also conclude the proposed action is not […]

Share

05
Jan

Household Pesticide Use Harms Infant Motor Skill Development

(Beyond Pesticides, January 5, 2022) Household pesticide use is associated with harmful impacts to infant motor development, according to a study published late last year in the journal Paediatric and Perinatal Epidemiology. The research focused on primarily low-income Hispanic women located in Los Angeles, California, enrolled in an ongoing study referred to as Maternal and Developmental Risks from Environmental and Social Stressors (MADRES). As with other pollutants in society, low-income, people of color communities are disproportionately in contact with toxic pesticides, resulting in exposures that can start early, and affect health over the course of one’s lifetime. Women enrolled in the MADRES cohort are over the age of 18, and speak English or Spanish fluently. For the present study, roughly 300 MADRES participants met the criteria for enrollment, and completed household pesticide use questionnaires at a 3-month post-natal visit. The questionnaire generally inquired whether pesticides had been used in one’s home since their child was born. After another 3 months, researchers also tested infants’ motor development using an Ages and Stages-3 protocol screening tool, which evaluates a child’s ability to execute muscle movements. Overall, roughly 22% of mothers reported pesticide use in their home during the first months of their […]

Share

16
Dec

Pesticides and Parkinson’s Disease: The Toxic Effects of Pesticides on the Brain

(Beyond Pesticides, December 16, 2021) A study by Shanghai Jiao Tong University, China, finds Parkinson’s Disease (PD) risk increases with elevated levels of organochlorine (OCP) and organophosphate (OP) pesticides in blood. Among patients with PD, specific organochlorine compounds have greater associations with cognitive impairments, including depression and brain function. Research finds exposure to chemical toxicants, like pesticides, can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, researchers suggest changes in protein enzyme composition and cellular dysfunction from pesticide exposure interrupt normal brain function. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses each year. The disease affects 50% more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While only 10 to 15 percent of PD incidences are genetic, PD is quickly becoming the world’s fastest-growing brain disease. Therefore, research like this highlights the need to examine alternate […]

Share

03
Dec

Degenerative Lung Diseases Associated with Atrazine Exposure, Worsened in Combination with Common Cancer Treatment

(Beyond Pesticides, December 2, 2021) A study published in Cellular Physiology and Biochemistry finds atrazine (ATR) exposure worsens lung disease outcomes in individuals with idiopathic (spontaneous) pulmonary fibrosis (IPF), a group of incurable lung diseases involving damaged/scarred lung tissue. Furthermore, chemotherapeutic products used to treat lymphoma (immune system cell cancer) like bleomycin can induce pulmonary fibrosis complications exacerbated by pesticide exposure. However, pesticide-related pulmonary fibrosis can have implications for neurological health, such as motor function. Scientific literature already finds an association between pesticide exposure and respiratory illnesses such as asthma, lung cancer, and chronic obstructive pulmonary disease (chronic bronchitis). Although IPF impacts over 5 million people a year globally, the disease is difficult to predict, which is concerning as the death rate is 50 to 56 percent within the first few years. Therefore, studies like this highlight the significance of evaluating how pesticide exposure impacts respiratory function, especially when exposure to respiratory toxicants increases vulnerability to existing respiratory-fixated illnesses like Covid-19. Advocate have urged the U.S. Environmental Protection (EPA) to incorporate scientific findings that these—where chemical exposures exacerbate an existing medical condition—into its pesticide registration review program. Researchers note, “[O]ur data represent an addition to the complex information on ATR-induced pulmonary toxicity. In particular, in this […]

Share

03
Nov

Researchers Uncovering Patterns that Help to Explain Chemical Sensitivities

(Beyond Pesticides, November 3, 2021) With a significant and increasing share of the U.S. population reporting sensitivities to certain chemicals, a team of researchers at University of California (Irvine), University of Texas (San Antonio), and the Massachusetts Institute of Technology is working to better understand how these symptoms develop. Although referred to by several names over the years, including Multiple Chemical Sensitivity (MCS) and Idiopathic Environmental Illness, medical professionals are now referring to the disease as Chemical Intolerance, or Toxicant Induced Loss of Tolerance (TILT), to better represent the disease process and range of nervous system symptoms that individuals develop to low level chemical exposures. “We established evidence of this previously understudied disease process,” said Shahir Masri, Sc.D, at University of California, Irvine. “Our insights will help public health scientists, physicians and policymakers better understand how to minimize harmful exposures and prevent future disease.” TILT is characterized by a two-step process. First, there is an “initiation exposure event,” whereby an individual is either repeatedly exposed to low levels of certain chemicals, or experiences a major exposure incident. In the second stage, affected individuals are “triggered” even by minute exposures, not only to the chemical that affected them in the first […]

Share

30
Sep

Commonly Used Neurotoxic Pesticide Exposure Increases ALS Risk to Workers and Residents

(Beyond Pesticides, September 30, 2021) Individuals working or living in areas with frequent neurotoxic pesticide use experience more amyotrophic lateral sclerosis (ALS) incidences than the general population. The study, published in NeuroToxicology, finds a positive association between sporadic (non-genetic, spontaneous) ALS incidences among individuals exposed to neurotoxic pesticides.  Amyotrophic lateral sclerosis (or Lou Gehrig’s disease) is a neurodegenerative disease that affects the nerves in the brain and spinal cord. As many as 16,000 – 20,000 Americans live with this condition, which weakens muscle/motor function leading to loss of muscle control for walking, talking, eating/swallowing, and breathing. Severe ALS progression is fatal and has no current cure. Although research supports genetic factors play a role in disease etiology (cause), most ALS cases do not result from genetic inheritance. Several research studies demonstrate exposure to environmental or work-related toxicants (i.e., pesticides) predispose humans to the disease. With researchers predicting a global ALS incidence increase of 69% by 2040, identifying ALS’s causal factors are important to future research. Therefore, research like this showcases the importance of assessing aggregate health risks associated with toxic chemical exposure, especially for illnesses, which are not curable. In this study, the researchers note, “[W]e identified pesticides applied to crops in the area of […]

Share

09
Sep

Endocrine (Hormone) Disrupting Chemicals, Including Pesticides, Also Affect the Nervous System

(Beyond Pesticides, September 9, 2021) A new study published in Toxicology Reports finds the same chemicals that disrupt the endocrine (hormone) system also disrupt the nervous system. Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem) present in nearly all organisms and ecosystems. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Past research shows exposure to endocrine-disrupting pesticides adversely affects human health, from reproductive function to cancer development, and effects can span generations. However, this study is one of the few to evaluate associations between endocrine-disrupting chemicals and neurological function. Although the etiology (cause) of many sporadic (non-heritable) neurological diseases are unknown, scientists suggest exposure to environmental toxicants plays a role in disease development. Therefore, government and health officials have been urged to consider how exposure to endocrine-disrupting chemicals can impact bodily function and development apart from hormone disruption.   In the body, cells communicate through electrical or chemical signals transmitted within the nervous or endocrine system. Studies find exposure to endocrine-disrupting chemicals has a direct and indirect impact on hormone function and development. However, researchers investigated whether […]

Share