(Beyond Pesticides, September 29, 2023) In unsurprising news, the Environmental Protection Agency (EPA) has reversed itself and decided not to ban a dangerous pesticide: tetrachlorovenphos (TCVP) used in pet flea collars and other flea products. This is despite its own earlier decision to ban TCVP in pet collars and scathing criticism of its methods and conclusions by the courts. First registered in 1966, TCVP belongs to the notoriously toxic organophosphate chemical family and is classified by the World Health Organization as “possibly carcinogenic to humans.” It was originally registered to Shell Chemical, then to E.I. duPont de Nemours, then to Hartz Mountain Corporation and Fermenta Animal Health Company.  Early on, it was registered for use on food crops and livestock, but the crop uses were voluntarily de-registered in 1987. It is still widely used on pets and farm animals. In 1995, EPA issued the opinion that “all uses of tetrachlorvinphos, with the exception of oral feed-through larvicide treatment to livestock intended for food use, will not cause unreasonable risk to humans or the environment.” Since then, the agency has contorted itself repeatedly to allow TCVP to remain on the market. There is little research available on TCVP’s human health effects; the […]

(Beyond Pesticides, September 21, 2023) A literature review published in Ciência & Saúde Coletiva finds environmental exposure to all classes of pesticides (fungicides, herbicides, insecticides) has an association with childhood astrocytoma (brain/central nervous system [CNS] tumor). CNS tumors represent half of all malignant neoplasms (tumors) in children. Although medical advancements in disease survival are progressing, childhood cancer remains the leading cause of death from disease among children. Furthermore, childhood cancer survivors can suffer from chronic or long-term health complications that may be life-threatening. The etiology or cause of childhood cancer involves the interaction of multiple components that include environment, lifestyle and genetics. However, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, pesticides, solvents, diet, etc.) affect disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues, resulting in chronic health effects. Children are particularly vulnerable to the impacts of pesticide exposure, as their developing bodies cannot adequately combat exposure effects. Moreover, several studies demonstrate an association between environmental or occupational pesticide exposure and the risk of childhood cancer. Considering that maternal pesticide exposure can have a stronger association with cancer among children than childhood exposure, and newborns can still encounter pesticides, it is […]

(Beyond Pesticides, August 31, 2023) A study published in Environmental Research finds glyphosate levels in the body adversely affect neurological health. Specifically, oral intake (e.g., eating contaminated foods), inhalation, and dermal exposure to glyphosate lowered cognitive function scores, heightened likelihood of severe depressive symptoms, and impaired auditory (hearing) function. Thus, this study provides some of the first evidence linking glyphosate exposure to specific neurological health outcomes among the general U.S. population, indicating the need for further studies on mechanisms driving neurotoxicity and the medical significance over time. Although this study is among the first to highlight specific neurological effects from glyphosate exposure among the general population, this study is not the first to identify potential neurotoxicity from glyphosate exposure. (Previous research cited below.) The ubiquity of glyphosate uses in agriculture—which leaves residues of the toxic chemical in food—and in public areas (e.g., parks, and walkways) may mean that exposures to it represent a significant risk factor for the disease. Glyphosate is already implicated or proven in developing numerous health anomalies, including cancer. The neurological system, including the brain, spinal cord, and a vast network of nerves and neurons, is responsible for many bodily functions—from sensation to movement. However, pesticides play various roles in […]

(Beyond Pesticides, July 11, 2023) A study published in Parkinsonism & Related Disorders finds high exposure to household pesticides increases the risk of developing Parkinson’s disease (PD) two-fold. There is a multitude of epidemiologic research on Parkinson’s disease demonstrating several risk factors, including specific genetic mutations and external/environmental triggers (i.e., pesticide use, pollutant exposure, etc.). However, several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Past studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the widespread commercialized use of household pesticides among the general population, few epidemiologic studies examine the influence household pesticides have on the risk of PD, although many studies demonstrate the association between PD onset via occupational (work-related) pesticide exposure patterns. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. Alzheimer’s ranks first. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and […]

(Beyond Pesticides, June 9, 2023) Glyphosate, usually marketed as the herbicide Roundup, has long been the poster child for shoddy regulation by both the U.S. Environmental Protection Agency (EPA) and the European Food Safety Authority (EFSA). In a study published June 1, 2023 in Environmental Health by Axel Mie and Christina Rudén, PhD, of Stockholm University and the Centre for Organic Food and Farming in Uppsala, the authors followed up on earlier work that documented deficiencies in information provided to European Union (EU) regulators by manufacturers. They identified nine studies on developmental neurotoxicity (DNT) that had been submitted to the U.S. Environmental Protection Agency (EPA) but were not disclosed to EU authorities. According to the research, seven of these studies would have “actual or potential regulatory impact.” According to the authors: “Of the nine undisclosed DNT studies, three were sponsored by Bayer and performed in their own laboratory. Three studies were sponsored by Syngenta and performed in their Central Toxicology Laboratory. One study each was sponsored by Nissan Chemicals and Ishihara Sangyo Kaisha (ISK), and these were performed at Huntingdon Life Sciences. For the remaining study, the sponsor and laboratory are unknown to us.” This study is a new example […]

(Beyond Pesticides, May 23 2023) New research is zeroing in on the role of 10 commonly used pesticides in the development of Parkinson’s. Published in the journal Nature Communications by a team of scientists lead by researchers at the University of California, Los Angeles, the study focused on the toxicity of these pesticides to neurons that have been found to lead to the presentation of the disease. Research is increasingly focusing on environmental exposures, and pesticides in particular, as a major factor in the development of Parkinson’s. This study adds further evidence that this line of research is a valid and worthwhile undertaking for the nearly one million people in the United States struggling with this incurable disease. [The authors note that the herbicide paraquat’s strong connection to Parkinson’s is not addressed in this study, but is the focus of a separate manuscript.] Scientists sought to further focus on which pesticides were most likely to be playing a role in Parkinson’s development. Records from California’s vast pesticide use database aided the search. From a comprehensive pesticide-wide association study, 53 of 288 pesticides screened were found to be linked to Parkinson’s. Scientists then took these 53 pesticides and conducted live-cell imaging […]

(Beyond Pesticides, May 11, 2023) A study published in NeuroToxicology finds occupational (work-related), chronic exposure to pesticides increases risk factors of epilepsy, a neurological disorder causing unprovoked, reoccurring seizures. Mounting evidence over the past years shows that chronic exposure to sublethal (low) levels of pesticides can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, this study suggests environmental pesticide exposure increases seizure risk through mechanisms at molecular or subcellular levels. Approximately 3.4 million individuals in the U.S. live with epilepsy, and mortality from this disorder is rising nationwide. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood and urine samples and can increase neurotoxicity risk when crossing the brain barrier. Considering half of all epilepsy etiologies (causes) are of idiopathic (unknown) origins, studies like this highlight the importance of understanding how consistent chemical exposure can impact long-term health and disease prognosis. The study notes, “[The] approach to a real-world exposure scenario to pesticides in a large agriculture area over 17 years; […] can be linked to the novel approaches proposed for simulating real-life exposures, thus contributing to a better understanding of the real-life risk associated with long-term […]

(Beyond Pesticides, May 5, 2023) Low level exposure to pyrethroid insecticides found in common pesticide brands like RAID and ORTHO result in neurodevelopmental damage to laboratory animals, reinforcing evidence of harm found in epidemiological studies on human exposure to these chemicals. According to research published in PNAS Nexus, mice exposed to the pyrethroid deltamethrin displayed atypical behavior similar to humans with developmental disorders. “We are not saying these mice have autism or that they have ADHD. That’s not the goal here,” said James Burkett, PhD, study coauthor and assistant professor of neuroscience in the UToledo College of Medicine. “What we are saying is that something in their brain has been altered by this exposure and it’s resulting in the same kinds of behaviors that we see in children with autism.” Scientists arrived at this determination by exposing a group of mouse mothers to consistent low levels of deltamethrin in their food during preconception, pregnancy, and lactation. The study notes that the amount of pesticide provided was “well below the benchmark dose for regulatory guidance.” A separate control group was given no pesticide in its food. Offspring from the female mice were then put through behavioral tests on social behavior, restrictive […]

(Beyond Pesticides, March 23, 2023) A case report article published in Frontier in Public Health confirms one of the first reported deaths from inhalation of the fumigant 1,3-dichloropropene (1,3-D or Telone) during work, resulting in acute renal (kidney) failure, hyperkalemia (high potassium levels in the blood), and brain edema (swelling). 1,3-D is a highly toxic fumigant used on a variety of crops, but primarily on potatoes, tobacco, strawberries, peanuts, and tomatoes to manage unwanted nematodes in soils. The chlorine-containing compound used in a greenhouse space entered the body of a 50-year-old man in China, being absorbed through the respiratory tract. Despite dilution from his wife, the compound was still strong enough to cause harm to human health. Without proper ventilation and personal protective equipment, wearing merely a surgical mask did not adequately defend against exposure to 1,3-D. This case represents the broader issue of how toxic chemical compounds can enter the body, causing physiological damage. Specifically, pesticides can increase the permeability (absorptiveness) of the blood-brain barrier that filters various molecules entering the brain from the circulatory system. However, the permeation of pesticide molecules elevates the expression and accumulation of soluble proteins in the brain involved in neuroinflammation, which plays a critical role in […]

(Beyond Pesticides, March 14, 2023) A study published in Environmental Research and Public Health finds occupational pesticide exposure increases the risk of sleep disorders among farmworkers and pesticide applicators. Specifically, many pesticides, like organophosphates (OPs), are detrimental to neurological function through inhibition of the enzyme acetylcholinesterase (AChE) responsible for ending a neurotransmission event after relaying the necessary information. Without an end to neurotransmission events, individuals experience a buildup of acetylcholine, resulting in convulsions, headaches, weakness, impacts on bodily senses, and other cognitive/mental changes. In addition to illnesses from chemical exposure, inadequate sleep has links to several chronic diseases like type 2 diabetes, cardiovascular disease, obesity, and depression. Therefore, given research links to sleep-related disorders and bodily functions, including endocrine, metabolic, neurological, and cognitive disorders, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The study notes, “The study’s findings can be used to create strategies for addressing mental health issues and promoting mental health and quality of life.” Researchers assess the sleep patterns among individuals living in southeast Spain, near the coast of Almeria, where chemical-intensive agriculture from greenhouses is prevalent. Of the 380 participants in the study, 189 were […]

(Beyond Pesticides, March 9, 2023) A study published in Environmental Research finds exposure to organophosphate (OP) compounds during pregnancy, or prenatal OP exposure can cause shortfalls in language development abilities at 18 months, stifling preschool-age language expression. Additionally, a timely and co-occurring study published in Environmental International confirms similar results, highlighting that chlorpyrifos (an organophosphate) impedes neurological and psychological development, including language communication and all motor skills of offspring at 12 and 18 months old. Prenatal development is one of the most vulnerable periods of exposure, as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. Given research links to pesticide exposure and neurological and cognitive development, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The Environmental Research authors note, “The etiology [cause] of language development is complex, and this work further highlights the importance of the prenatal environment as a mechanism of influence that are associated with deficits in early language acquisition and ability, which could signal increased behavioral problems and academic difficulties in later childhood that extend […]

(Beyond Pesticides, January 19, 2023) Research published in Environmental Health Perspectives finds the presence of nine various neonicotinoids (neonics) and six neonic metabolites within human cerebrospinal fluid (CSF). CSF is an essential part of the central nervous system (CNS), especially for CNS development. Specific chemical biomarkers (measurable indicators of biological state), like pesticides, found in CSF are useful for diagnosing and evaluating numerous neurological diseases. The nervous system is an integral part of the human body and includes the brain, spinal cord, a vast network of nerves and neurons, all of which are responsible for many of our bodily functions—from sensed to movement. However, mounting evidence over the past years shows that chronic exposure to sublethal (low) levels of pesticides can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. The impacts of pesticides on the nervous system, including the brain, are hazardous, especially for chronically exposed individuals (e.g., farmworkers) or during critical windows of vulnerability and development (e.g., childhood, pregnancy). Researchers identify the role agricultural chemicals play in CNS impacts causing neurological diseases, like amyotrophic lateral sclerosis (ALS) and Parkinson’s disease, dementia-like diseases such as Alzheimer’s, and other effects on cognitive function. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood […]

(Beyond Pesticides, January 12, 2023) Exposure to certain pesticides among individuals diagnosed with Parkinson’s disease (PD) can increase the risk of symptom progression. According to a study published in Science of the Total Environment, nearly 20 percent of pesticides associated with the onset of PD also increase the risk of faster decline in motor and non-motor function. Several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Past studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the association between PD onset via pesticide exposure patterns, few epidemiologic studies examine the influence pesticides have on worsening motor and non-motor symptoms in PD. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While […]

(Beyond Pesticides, January 9, 2023) The Biden EPA still needs a new vision in order to meet the existential crises in public health, climate change, and biodiversity. The Trump Environmental Protection Agency (EPA) reversed in four years much of the progress made by the EPA in decades. Despite a broad new perspective embodied in President Biden’s Executive Memorandum (EM) Modernizing Regulatory Review issued on his first day in office, the Biden EPA has not adopted a new direction for regulating pesticides. Tell President Biden, EPA, and Congress to adopt a new direction for pesticide regulation. Immediately following his inauguration, President Joe Biden issued the EM, which directs the heads of all executive departments and agencies to produce recommendations for improving and modernizing regulatory review, with a goal of promoting public health and safety, economic growth, social welfare, racial justice, environmental stewardship, human dignity, equity, and the interests of future generations. This EM could reverse the historical trend of status-quo regulatory reviews required by the White House Office of Management and Budget (OMB) that typically support vested economic interests of polluters (e.g., petroleum-based pesticide and fertilizer manufacturers). The President’s EM sets the stage for the adoption of agency policy across government to […]

(Beyond Pesticides, January 3, 2023) The California Department of Pesticide Regulation (DPR) announced new rules that remove existing limits on the use of 1,3-dichloropropene (1,3-D or Telone), allowing Californians to breathe much more 1,3-D than state toxicologists in the Office of Environmental Health Hazard Assessment (OEHHA) say is safe and highlighting the dangers to which farmworkers are routinely exposed. It is outrageous that the state of California and the U.S. Environmental Protection Agency (EPA) would allow farmworkers—whose labor was judged “essential” during the pandemic—to be routinely exposed to highly toxic pesticides, which could be replaced by organic practices. While the state of California describes its action as increasing protection, advocates point to continued use, unacceptable harm, and the availability of alternative organic agricultural production methods that eliminate the use of 1,3-D. Since over a third of the country’s vegetables and three-quarters of the country’s fruits and nuts are grown in California, most people who buy their food in a grocery store have a stake in how food is grown in the state and the impact that it has on those who live and work there. Tell the state of California, U.S. EPA, an the U.S. Congress to cancel the registration […]

(Beyond Pesticides, October 19, 2022) Pet flea collars containing the insecticide tetrachlorvinphos (TCVP) are set to be banned by the U.S. Environmental Protection Agency, according to the agency’s long overdue response to a petition from the Natural Resources Defense Council (NRDC). The highly toxic pesticide has not been used on crops since 1987, yet was permitted for decades in flea collars where children could be intimately exposed to the chemical while petting and playing with the family pet. The decade-long process of bringing use of these products to an end exposes the failures of the U.S. pesticide regulatory system, and how EPA’s weak and flawed decisions that infect the marketplace with severe consequences. One may ask: How many veterinarians prescribed these dangerous flea collars to pet owners, assuming that EPA has properly assessed exposure risks to their human owners? Advocates concerned about EPA’s ongoing propensity to defer to the pesticide industry are urging an overhaul of the regulatory process and a reorientation toward toxic pesticide elimination and the adoption of organic in order to address serious health and environmental threats. NRDC originally filed its petition to ban all uses of TCVP in 2009. The petition noted that the agency completely […]

(Beyond Pesticides, October 5, 2022) Exposure to widely used synthetic pyrethroids, present in many mosquito adulticides and household insecticides like RAID, is associated with a diagnosis of rheumatoid arthritis, according to research published in Environmental Science and Pollution Research. This is the latest pesticide-induced disease associated with this dangerous class of chemicals – a harm to individual Americans that the U.S. Environmental Protection Agency (EPA) is not considering when it registers pesticides. To remedy the major deficiencies in EPA’s reviews, and protect residents from chronic disease, more and more communities are transitioning to safer, organic pest management practices that do not require pyrethroids and other toxic synthetic pesticides. Rheumatoid arthritis (RA) is an autoimmune disease that causes systemic inflammation throughout the body, resulting in progressive damage to an individual’s joints. In the United States, roughly 1.3 million adults suffer from RA, accounting for nearly 1% of the adult population. Health care costs associated with the disease reach nearly $20 billion annually. To better understand the etiology behind the disease, an international team of researchers from China, Illinois, and Missouri analyzed data from the 2007-2014 National Health and Nutrition Examination Survey (NHANES), a long-running program that began in the early 1960s […]

(Beyond Pesticides, August 30, 2022) Minuscule amounts of the weed killer Roundup and its active ingredient glyphosate can result in damage to the nervous system, finds research led by scientists at Florida Atlantic University, published in Scientific Reports. As hundreds of millions of pounds of glyphosate continue to be sprayed on hundreds of millions of acres of land throughout the United States each year, recent data indicate that four out of five U.S. children and adults contain detectable levels of glyphosate in their bodies. The pesticide industry and its paid supporters tell Americans that although contamination is widespread, the levels found in humans are not cause for concern. This latest research significantly undermines that specious argument, finding impacts on critical nervous system processes at levels 300 times less than the lowest suggested amount on the Roundup label. “It is concerning how little we understand about the impact of glyphosate on the nervous system,” said Akshay S. Naraine, MSc., coauthor and a PhD student at Florida Atlantic University. “More evidence is mounting for how prevalent exposure to glyphosate is, so this work hopefully pushes other researchers to expand on these findings and solidify where our concerns should be.”  To investigate the […]

(Beyond Pesticides, August 24, 2022) New research is helping the medical community understand the mechanism through which exposure to the banned insecticide DDT increases risk of Alzheimer’s disease. Published in the journal Environmental Health Perspectives, a team of researchers from Florida International University and Rutgers used multiple models to demonstrate the effects of DDT on the production of toxic proteins in the brain. The constant stream of new health risks regarding a chemical banned decades ago underlines the importance of a precautionary approach to pesticide regulation, particularly as red flags are already being raised about the connection between widely used weed killers like glyphosate and neurodegenerative diseases like Alzheimer’s. “The vast majority of research on the disease has been on genetics — and genetics are very important — but the genes that actually cause the disease are very rare,” says study coauthor Jason Richardson, PhD of Florida International University. “Environmental risk factors like exposure to DDT are modifiable. So, if we understand how DDT affects the brain, then perhaps we could target those mechanisms and help the people who have been highly exposed.” Previous research from Dr. Richardson found that DDT exposure increased risk of Alzheimer’s by four times. Scientists […]

(Beyond Pesticides, August 4, 2022) An Arizona State University (ASU) study shows that the popular herbicide glyphosate can infiltrate the brain through the blood (blood-brain barrier), increasing neurological disease risk. The blood-brain barrier filters various molecules entering the brain from the circulatory system. However, the permeation of glyphosate molecules elevates the expression of TNFα and the accumulation of soluble beta-amyloid (Aβ) proteins in the brain and has associations with immune, inflammatory, and neurodegenerative diseases like Alzheimer’s disease (AD). More than 6 million people in the U.S. are living with Alzheimer’s, and cases are expected to double by 2050. Although Alzheimer’s research has focused heavily on finding genetic causes of the disease, fewer than half of cases are genetic. Thus, researchers are now evaluating how environmental contaminants may increase disease risk. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood and urine samples and can increase neurotoxicity risk when crossing the brain barrier. Therefore, studies like this highlight the importance of understanding how chemical accumulation in the body can impact long-term health and disease prognosis. The study notes, “Brain glyphosate correlates with increased TNFα levels, suggesting that exposure to this herbicide may trigger neuroinflammation in the brain, which may […]

(Beyond Pesticides, June 30, 2022) A study by Zhongnan University and Shandong University in China finds that the broad-spectrum fungicide maneb increases Parkinson’s disease (PD) risk and development through alterations in protein and metabolite pathways, resulting in neurotoxicity. Several studies find exposure to chemical toxicants, like pesticides, have neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, this study suggests neurological damage from oxidative stress, cell dysfunction, and synapses impairment, among others, increases the incidence of PD subsequent to pesticide exposure. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While only 10 to 15 percent of PD cases are genetic, PD is quickly becoming the world’s fastest-growing brain disease. Therefore, research like this highlights the need to examine molecular mechanisms involved in altering chemical […]

(Beyond Pesticides, May 26, 2022) A study published in The International Journal of Biochemistry & Cell Biology finds environmental exposure to neurotoxic pesticides increases Parkinson’s Disease (PD) risk through gastrointestinal (GI) disruption. Research finds exposure to chemical toxicants, like pesticides, can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, this study suggests environmental pesticide exposure disrupts GI cells responsible for supporting the autonomic nervous system. Enteric glial cells (EGCs) are GI cells that play a critical role in the functional changes that accompany GI dysfunction, as this dysfunction is one of the earliest symptoms indicating the onset of PD. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses each year. The disease affects 50% more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Identifying early biomarkers of PD, such as pesticide-mediated toxicity on GI cells, is crucially important as symptoms intensify overtime, with no current cure for this fatal disease. While only […]

(Beyond Pesticides, May 23, 2022)  The climate change-induced increase in wildfire frequency and intensity has lent new urgency to efforts to manage so-called “invasive” plants. Unfortunately, the herbicide-based approach favored by many is both counterproductive and hazardous. It must be replaced by an organic system, incorporating biological control agents like goats and establishing a more resilient ecology.    Tell your county/city officials to replace herbicides with organic vegetation management. Tell EPA and Congress that herbicides must be evaluated in the context of the availability of organic systems. Use of the herbicide indaziflam is an example of the ineffectiveness of management based on herbicides. While indaziflam is considered a “selective” herbicide, it actually kills and prevents germination of a wide range of broad-leaved plants and grasses and comes close to being a soil sterilant. The action on seedlings is long-lasting, thus inhibiting the growth and establishment of a resilient plant community that is resistant to invasion. Given its persistence and nonselective action and the extent of the damage it causes to native soil seed banks and plant biodiversity, indaziflam could contribute to the eventual ecological collapse of ecosystems where it’s applied, similar to the cascading impacts of the systemic insecticides, fipronil and […]