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As Millions Die from Antibiotic-Resistant Infections Annually, Study Shines Light on Pesticide Connection

Friday, July 11th, 2025

(Beyond Pesticides, July 11, 2025) Pesticides and antibiotics are linked inextricably in the looming crisis of human and ecosystem health. Both started out as quasi-miraculous solutions to age-old human problems, yet it has been clear that the failures of each present severe challenges—and that they are synergistic because they trigger the same kinds of defensive mechanisms in their targets: insects, fungi, and weeds on the one hand, and microbes on the other. A review of contamination of waterways in India with pesticides and antibiotics, published in Environmental and Geochemical Health, recounts the many threats that arise when these chemicals mix and how their presence in water makes the problems much worse.    Globally, about five million people died in 2019 from infections with antibiotic-resistant microbes. By 2050, according to a World Bank estimate, antibiotic resistance could add $1 trillion to global health care costs and subtract $3.4 trillion from annual global gross domestic product. While the world slowly realizes the urgent need to counter antibiotic resistance, the role of pesticides in generating it has received less political and public attention. But there is no doubt that pesticides are strongly implicated. In fact, the resistance of microbes to antibiotics is no […]

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Tanzania at a Crossroads, Building an Organic Future after Decades of Toxic Pollution

Wednesday, July 9th, 2025

(Beyond Pesticides, July 9, 2025) Policymakers in Tanzania are calling for increased investments in organic agriculture for the 2025/26 fiscal year budget, demonstrating the increase in political will to advance new systems of farming and land management after decades of relying on Green Revolution-style, or chemical-intensive, policies. On June 20, various ministers representing the national government presented speeches to Parliament on the national government’s plan and budget recommendations, as well as highlighting the previous fiscal year’s trends and use of funds.   Political and popular support for organic agricultural systems has gained momentum across the globe. Worldwide, organic farming practices quadrupled from 2000 to 2018, with over 180 countries supporting a global transition to organic agriculture. Newly published global survey data by the Research Institute of Organic Agriculture (FiBL) and International Federation of Organic Agriculture Movements – Organics International (IFOAM) reveal global organic agriculture to be at an all-time high, with 71.5 million hectares of farmland in production as of 2020. (See Daily News here). Farmer and agricultural cooperatives around the world, from Brazil to Madagascar and Togo, leverage organic systems to develop competitive business models in regional, national, and international markets. (See Daily News here.) The European Union, with […]

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Study Maps the Gut Microbiome and Adverse Impacts of Pesticide Residues

Wednesday, June 11th, 2025

(Beyond Pesticides, June 11, 2025) Researchers developed a novel tool* in a recent study published in Nature Communications this year that successfully creates a map of the “pesticide-gut microbiota-metabolite network,” identifying “significant alterations in gut bacteria metabolism.” While the study authors acknowledge that this is not a complete map, since they selected specific pesticides and bacterial partners, the research adds to the body of peer-reviewed scientific literature that underscores the relationship between pesticide residues and human gut health. Organic farmers, as well as any land steward invested in agroecological practices and soil health, understand that microbial life (both in the body and in the soil) is dangerously undermined by the status quo of chemical-intensive land management. Background and Methodology The researchers leverage mass spectrometry to test metabolite (metabolomics) and lipid (lipidomics) relationships with pesticide residues, as well as an in vivo mouse model. *The map itself is a form of computational biology, which advocates have warned could be a false solution if not accompanied by other proven scientific methods. See here for analysis by the Natural Resources Defense Council on risks of unproven methods such as New Approach Methodologies [NAMs]. All major phylogenetic (“evolutionary relationships among biological entities”) groups are […]

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Soil Nematodes Vital to Plant Health Threatened by Nontarget Pesticide Exposure, Study Finds

Friday, May 9th, 2025

(Beyond Pesticides, May 9, 2025) Research in Advances in Modern Agriculture showcases how pesticide residues can threaten the health of soil nematodes and cause phytotoxic effects in cucumber plants. In assessing both the sprayed vegetables and the organisms within the soil, the authors find a negative correlation between pesticide exposure and soil nematode populations that is proportional to the application rates of the chemicals, as well as alterations in plant development. These impacts highlight potential wider effects on crop productivity, biodiversity, and human health. “Nematodes, which are microscopic worms inhabiting the soil, are vital contributors to soil vitality and the cycling of nutrients,” the authors share. “Nonetheless, the non-selective and widespread application of pesticides can negatively impact these organisms, leading to potential detriments in soil quality and plant vitality.” “Pesticide residues have the propensity to be absorbed and progressively accumulate as they traverse from soil to plants and subsequently to humans,” the researchers state. They continue, “The specific characteristics of the pesticide and its interactions with the body across different levels dictate whether it will be excreted without causing significant harm or if it will accumulate, potentially leading to enduring subclinical and clinical ramifications.” The impacts vary widely between organisms […]

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Children Exposed to Pesticides Experience “Cellular Distress” and Chronic/Acute Diseases, Study Finds

Friday, February 28th, 2025

(Beyond Pesticides, February 28, 2025) It is well established that children are more vulnerable than adults to environmental insults such as pesticides, from conception onward. Children living in agricultural areas are exposed differently from those in urban areas. A study of rural children by researchers at Mexico’s Universidad AtĂłnoma de Nayarit compared two communities located less than a quarter of a mile from agricultural fields with one control community located more than a mile away. The study shows that children in the field-adjacent towns are clearly exposed to pesticides and are experiencing cellular distress as a result. The state of Nayarit is on the west coast of Mexico near Mazatlan. Rural children encounter aerial application, spray drift, and erosion. If their parents are agricultural workers and especially if they apply pesticides, they bring home residues on their clothes. Residential storage of pesticides and small children’s propensity to play in the dirt and put things in their mouths exacerbate their exposure. Urban children get hit by pesticides in their homes, schools, and parks. The researchers took blood and urine samples from 431 children aged six to 12 and collected questionnaires as to pesticide exposures from the parents or guardians. They assayed the […]

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Sleep Disorders in Farmers and Farmworkers Linked to Pesticide Exposure in Study Supporting Similar Findings

Friday, January 31st, 2025

(Beyond Pesticides, January 31, 2025) A recent cross-sectional study in Heliyon highlights the link between sleep disorders in Thai farmers and pesticide exposure. The authors find pesticide exposure as an important risk factor for sleep disorders after surveying 27,334 farmers over the age of 20 who had work experience for at least five years. The importance of sleep health is reflected both physically and mentally, as studies find “sleep deficiency increase[s] mortality and various health complications, including hypertension, obesity and type 2 diabetes, cardiovascular diseases, mood disorders, and neurodegenerative disorder.” Additional studies find that these issues are compounded when sleep health is affected by environmental factors such as pesticide exposure. (See previous Beyond Pesticides’ coverage here and here.) The researchers report: “The study found a positive association of 19 individual pesticides (twelve insecticides, two herbicides, and five fungicides). Some associations demonstrated a dose-response pattern. Additionally, the study revealed that women are at a higher risk of sleep-related issues with pesticide exposure compared to males. These results not only substantiate existing literature but also unveil several new individual pesticides that may impact sleep health.” Focusing on study participants in Thailand, which is “characterized by heavy pesticide use and minimal protective measures, […]

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Multitude of Studies Find Epigenetic Effects from PFAS and Other Endocrine Disrupting Pesticides

Thursday, January 16th, 2025

(Beyond Pesticides, January 16, 2025) In Ecotoxicology and Environmental Safety, researchers highlight a multitude of studies on endocrine disrupting chemicals (EDCs) and endocrine disrupting pesticides (EDPs) showing epigenetic effects from exposure. These EDCs imitate the action of endocrine hormones and lead to gene damage and multigenerational adverse effects to health. “These chemicals can interfere with the normal functioning of target tissues by altering their response to hormonal signals, thereby affecting various physiological processes including reproduction, development, the nervous system, the immune system, and even the process of carcinogenesis [causing cancer],” according to the authors from Hebei Agricultural University and Chinese Academy of Agricultural Sciences.   In causing epigenetic modifications, the authors describe that EDCs can create changes “at the nuclear and mitochondrial DNA (nDNA and mtDNA) or RNA levels, without changing the underlying DNA sequence. These alterations modify the structure or conformation of DNA, influencing gene expression and, consequently, cellular function.” They continue, “The mechanisms of epigenetics include changes in DNA methylation, chromatin modifications and the involvement of certain noncoding RNAs.” In reviewing over 80 studies on EDCs, predominantly fluorinated compounds such as per- and polyfluoroalkyl substances (PFAS), the researchers provide a summary of linkages between pesticide exposure and the […]

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Multiple Studies Link Adverse Effects on Female Reproductive Health with Endocrine Disrupting Chemical Exposure

Thursday, January 9th, 2025

(Beyond Pesticides, January 9, 2025) In a Frontiers in Public Health review article, researchers report on the wide body of science connecting adverse effects to female reproductive system, such as infertility, with exposure to endocrine-disrupting chemicals (EDCs). The authors call these effects a significant concern for public health, as there has been growing evidence of EDCs with risk factors for decreased fertility.   Infertility “affects a substantial proportion of the world’s population with approximately one in six people affected,” the researchers note. They continue: “Over the last 70 years, global fertility has been constantly in decline due to behavioral and societal changes… [E]merging evidence has shown that infertility incidence is linked to exposure to environmental factors such as tobacco, alcohol, and a wide range of endocrine-disrupting chemicals (EDCs) including pesticides (chlorpyrifos, glyphosate, dichlorodiphenyltrichloroethane [DDT] and methoxychlor), phthalates, polychlorinated biphenyls (PCB), dioxins, and bisphenols.”  In this review, over 100 studies are summarized to showcase the link between EDC exposure and reproductive effects in women, including infertility and related diseases such as endometriosis, premature ovarian insufficiency (POI), and endocrine axis dysregulation. The studies included investigating the “mechanisms by which EDCs cause ovarian aging, folliculogenesis, decrease of oocyte quality, ovulation disorders, development and receptivity […]

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Study Adds to Understanding of Importance of Soil Health to Ecosystem Stability and Biodiversity

Friday, November 1st, 2024

(Beyond Pesticides, November 1, 2024) In a study published earlier this year in Soil Science Society of America Journal, researchers at Kansas State University document direct evidence that organic amendments (e.g., manure and compost) in a no-till agricultural system “facilitat[e] microbial diversity” that cycles plant-available nutrients. The study was published just as farmers are looking for less expensive practices that support the economic vitality of their farms amid surging prices for petrochemical pesticides and fertilizers and as agricultural support programs are threatened by unresolved issues in Farm Bill talks on Capitol Hill. [See the recent Action of the Week calling on Congress to take action.] Simultaneously, awareness is growing among environmental and public health advocates about the importance of soil health to ecosystem stability in combatting climate change-induced natural disasters and stopping plummeting biodiversity. Demands for new systems rooted in organic principles and land management practices continue to become more widely recognized by farmers, environmentalists, and the broad public. The study adds to earlier findings and contributes to the body of scientific literature on soil health and its importance to ecosystem and human health. Methodology and Results The study was led by researchers at Kansas State University specializing in agronomy […]

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Study Links Endocrine-Disrupting Chemicals to Thyroid Dysfunction with Grave Health Effects

Tuesday, October 8th, 2024

(Beyond Pesticides, October 8, 2024) A comprehensive literature review in Endocrines, published in September, amasses hundreds of studies on endocrine-disrupting chemicals (EDCs) that showcase adverse effects on growth, development, reproduction, and metabolism. The authors, a team of scientists and academics from Brazil, shed light on the link between EDC use and thyroid dysfunction, leading to increasingly prevalent illnesses and deadly diseases.     EDCs are any synthetic or natural compounds that hinder endocrine system functions and create harmful effects on organisms. These chemicals can impact the thyroid gland, which is vital in producing hormones and plays a role in several body functions. As the researchers state, “Several EDCs have been classified as thyroid disruptors, impairing thyroid hormone [TH] production, synthesis, metabolism, transport, and/or actions. Notably, thyroid disorders are the second most prevalent endocrine disease worldwide, with incidence increasing significantly in recent years.” The authors continue, “[S]tudies have correlated this rise in thyroid dysfunctions and cancers with increased exposure to EDCs. Although many EDCs are linked to thyroid dysfunction, this review focuses on the deleterious effects of plasticizers, organochlorine pesticides, and per- and poly-fluoroalkyl substances on thyroid function. These contaminants are commonly found in food, water, and everyday products.” This review helps […]

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Pesticide Residue Impacts Microbial Health

Tuesday, September 17th, 2024

(Beyond Pesticides, September 17, 2024) Today, International Microorganism Day, is a prime moment to focus on the complexity of billions of living beings that establish the foundation of land management and food production. Organic advocates, community members, and farmers identify the protection and enhancement of biological diversity in the soil as a key goal, especially in light of mounting concerns over rising microbial resistance to chemical-intensive practices. A recent article in British Journal of Environmental Sciences points to several microbial populations adversely affected by pesticide-contaminated soil on various farmland plots in Nigeria. There are significant variations in bacteria presence between pesticide-treated and control plots, with a lab analysis finding “[s]eventy-five percent (75%) of pesticide residue was detected in the soil samples,” which includes paraquat dichloride, endosulfan, diazinon, and N-(phosponomethyl)glycine [glyphosate]. This report builds on years of research from higher education institutions worldwide, including participatory research centering applied experiments on farmland, demonstrating the consequences of relying on pesticide-intensive agriculture and land management. The main goal of this report is to “determine the influence of pesticide contamination on the microbial population, physiochemical parameters and pesticide residue of soil of selected farmlands in Otuoke, Bayelsa State, Nigeria.” Researchers document the presence of eleven […]

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Scientific Literature Review Again Links Pesticides to a Range of Illnesses and Ecological Decline

Wednesday, September 4th, 2024

(Beyond Pesticides, September 4, 2024) A study in the Journal of Environmental Science and Public Health adds to the body of science that highlights the ecological decline threatening all species as a result of hazardous chemicals in the environment. “When environmental changes undermine a species’ or population’s ability to survive, it is said to be in an ecological crisis,” the authors state. They continue, “Pesticides, particularly persistent organic pollutants (POPs), are among the top ten chemicals and hazardous compounds that the WHO [World Health Organization] has recognized as being a concern for global health. The overuse and improper handling of agrochemicals is the primary driver of the ecological disaster.”   The researchers, from the Post Graduate Institute of Medical Education and Research in India, conducted a literature review to look broadly and comprehensively at the range of factors that contribute to adverse health effects (from breast cancer to genotoxic effects, chronic kidney disease, neurotoxicity, and more). They searched PubMed and Google Scholar for studies between 2004-2024 for relevant information on soil health, sustainable agriculture, food security, soil security, and the associations with human health. Their scientific findings lead the authors to conclude that the building of healthy soils will eliminate the need […]

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Toxic Pesticides Increase Rates of Chronic Kidney Disease in Agricultural Communities

Thursday, August 22nd, 2024

(Beyond Pesticides, August 22, 2024) A screening and analysis of 36 pesticides finds traces of these chemicals in patients with “unexplained chronic kidney disease” from agricultural communities in the Indian province of Uttar Pradesh. Researchers conducting this study, published in the Journal of Toxicology and Environmental Health Sciences, identify organophosphates, organochlorines, and pyrethroids as the main culprits, building on years of existing research pointing to adverse health impacts originating from bioaccumulation of pesticides after acute and chronic exposure. Chronic kidney disease (CKD) is a condition that afflicts one in ten adults internationally, based on a peer-reviewed analysis from The Lancet. The Centers for Disease Control and Prevention (CDC) estimate that one in seven U.S. adults (or roughly 35.5 million people) have CKD, with as many as nine in ten adults with the disease undiagnosed, based on 2023 data. The correlation between high rates of CKD and multigenerational use of and reliance on pesticides for food production, lawn care, and general land management reinforces the calls of advocates, farmers, and health professionals to adopt a new approach rooted in organic principles. Methodology This study was conducted by a group of researchers from the Department of Chemistry at Babu Banarasi Das University […]

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Over 60 Biomarkers of Pollutants and Pesticides Found in Hair Analyses of French Children

Wednesday, August 7th, 2024

(Beyond Pesticides, August 7, 2024) Using mass spectrometry techniques, researchers in Luxemburg and France detect 69 biomarkers of pollutants and pesticides—12 of which are banned—in hair samples from over 200 French children. This study, published in Environment International, is the first to target over 150 biomarkers in a single hair sample, which “represents the most comprehensive assessment of chemical exposome in humans,” the authors say. All children in the study were 3.5 years old and recruited from the Étude Longitudinale Française depuis l’Enfance (ELFE) [French Longitudinal Study since Childhood] cohort in the country of France, a major pesticide consumer in Europe. The ELFE survey is a joint project between the French Institute for Demographic Studies (INED) and the National Institute of Health and Medical Research (INSERM), which provides the first comprehensive national scientific investigation of children in France by following them from birth to adulthood. Through analysis of hair samples from children in the ELFE cohort, this study evaluates pesticide exposure and compares it with prenatal exposure data from their mothers while also, according to the scientists, “investigat[ing] the roles of children’s biological sex and geographical differences as possible determinants of exposure.” Exposure to pesticides during early childhood poses significant […]

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Cross-Sectional Study Finds Connection Between Pesticide Exposure and Alzheimer’s Disease

Wednesday, June 5th, 2024

(Beyond Pesticides, June 5, 2024) Individuals living near chemical-intensive agricultural environments have heightened risk of Alzheimer’s disease relative to the general population, according to a study published earlier this year in Psychiatry Research. This finding builds on existing peer-reviewed studies that document the relationship between chronic pesticide exposure and elevated risk of neurodegenerative disorders including Alzheimer’s disease, as well as Parkinson’s disease, dementia, multiple sclerosis (MS), and Huntington’s disease. In light of the mountains of scientific evidence, advocates continue to demand for a wholesale transformation of agricultural and land management systems to one based in organic principles in alignment with the U.S. National Organic Program. Study Analysis This study was published online on May 1, 2024 with the full entry to be published in July 2024. The researchers are physicians, health professionals, and professors at the University of Almeria in southern Spain, specifically working in the Health Research Center and the Department of Nursing, Physiotherapy and Medicine. There is also a researcher, Cristofer Ruiz-GonzĂĄlez, who works at the TorrecĂĄrdenas University Hospital also located in Almeria, Spain. Researchers gathered case information from over 40,000 patients between 2000 and 2021 living in demarcated health care districts with high and low levels of […]

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Residential Areas and Early Postnatal Complications for Pregnant Women Tied to Banned and Current Pesticides

Wednesday, May 31st, 2023

(Beyond Pesticides, May 31, 2023) A study published in Chemosphere supports accumulating scientific research confirming that prohibited and current use pesticides are readily detectable in the human placenta. All pregnant women experience exposure to a mixture of complex pesticides like DDT (prohibited organochlorine pesticide [OCP]) and chlorpyrifos (current use organophosphate [OP]), with concentrations high enough to increase possible adverse health risks to the fetus through a placental transfer of chemicals. Prenatal development in the intrauterine environment is one of the most vulnerable periods of exposure, as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. Given the over 1,300 research studies that demonstrate the link between pesticide exposure and general health effects, studies like this can help government and health officials identify how pesticides’ impact on the body elevates health concerns, especially for future and developing generations. The authors note, “This study highlights the urgent requirement for implementing alternative pest-control methods in agriculture, involving a reduction of chemical pesticides application. Due to the vital role of the placenta in fetal development and its non-invasive sampling, this kind of […]

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New Study Spotlights Ten Pesticides Implicated in Development of Parkinson’s

Tuesday, May 23rd, 2023

(Beyond Pesticides, May 23 2023) New research is zeroing in on the role of 10 commonly used pesticides in the development of Parkinson’s. Published in the journal Nature Communications by a team of scientists lead by researchers at the University of California, Los Angeles, the study focused on the toxicity of these pesticides to neurons that have been found to lead to the presentation of the disease. Research is increasingly focusing on environmental exposures, and pesticides in particular, as a major factor in the development of Parkinson’s. This study adds further evidence that this line of research is a valid and worthwhile undertaking for the nearly one million people in the United States struggling with this incurable disease. [The authors note that the herbicide paraquat’s strong connection to Parkinson’s is not addressed in this study, but is the focus of a separate manuscript.] Scientists sought to further focus on which pesticides were most likely to be playing a role in Parkinson’s development. Records from California’s vast pesticide use database aided the search. From a comprehensive pesticide-wide association study, 53 of 288 pesticides screened were found to be linked to Parkinson’s. Scientists then took these 53 pesticides and conducted live-cell imaging […]

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Beehive Products Contain Concentration of Pesticide Residues High Enough To Be a Risk to Consumer Health

Thursday, May 18th, 2023

(Beyond Pesticides, May 18, 2023) A study published in Food and Chemical Toxicology finds pesticide residues in beehive products pose a safety risk from dietary consumption. Beehive products (i.e., bee bread, propolis, beeswax, and royal jelly) from beekeeping or apiculture are said to have nutraceutical (health and medicinal benefits) properties. However, a wide range of pesticide residues (i.e., tau-fluvalinate, coumaphos, chlorfenvinphos, chlorpyrifos, and amitraz), especially acaricides for killing ticks and mites in hives, may accumulate in beehive products up to concentrations that pose a potential health risk. Environmental contaminants like pesticides are ubiquitous in the environment, with 90 percent of Americans having at least one pesticide compound in their body. Many of these chemical compounds remain in soils, water (solid and liquid), and the surrounding air at levels exceeding U.S. Environmental Protection Agency (EPA) standards. Therefore, individuals still encounter pesticide compounds at varying concentrations, adding to the toxic body burden of those harmful chemicals currently in use. The research methodology includes a review of the scientific literature on pesticide contamination in hive products and a dietary risk assessment. The risk assessment calculation uses scientific studies to determine the recommended daily intake values and concentration data. Researchers compare exposure values in products to health-based guidance, determining the potential acute and […]

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Estrogen-Mediated Cancers in Humans Have Links to Endocrine Disrupting Pesticides

Tuesday, December 13th, 2022

(Beyond Pesticides, December 13, 2022) Pesticides have a long history associated with hormone (endocrine)-disrupting properties that induce various molecular changes, prompting disease development. Adding to the science, a review published in Environmental Exposure, Biomonitoring and Exposure Assessment highlights how specific estrogen-mimicking pesticides increase the risk of disease, particularly hormone-related cancers among women (i.e., breast, ovarian, endometrial cancer) and men (i.e., testicular, prostate cancer). Like pesticides, endocrine disruptors are xenobiotic (i.e., chemical substances foreign to an organism or ecosystem). Many reports demonstrate that exposure to endocrine-disrupting chemicals can adversely affect human, animal—and thus environmental—health by altering the natural bodily hormones responsible for conventional reproductive, physical, and mental development. Endocrine disruption can lead to several health problems, including hormone-related cancer development (i.e., thyroid, breast, ovarian, prostate, testicular), reproductive dysfunction, and diabetes/obesity that can span generations. Therefore, studies related to pesticides and endocrine disruption help scientists understand the underlying mechanisms that indirectly or directly cause cancer, among other health issues. Pesticides are one of the most potent xeno-estrogenic compounds, as estrogenic strength and environmental half-life exceed those of other xeno-estrogenic compounds. Focusing on organochlorine pesticides (OCs), the study evaluates the chemical effects on the physiological (anatomic) system to increase cancer risk. Using human studies, researchers assessed how estrogen-medicated cancer develops in women and men. […]

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Banned Pesticides in Well Water Linked to Declines in Kidney Function

Wednesday, January 12th, 2022

(Beyond Pesticides, January 12, 2022) Well water in agricultural regions of Sri Lanka is contaminated with highly hazardous insecticides and associated with a decline in kidney function, according to research published in npj Clean Water this month. This finding is the latest piece in an ongoing ‘puzzle’ regarding the epidemic of chronic kidney disease of unknown origins in Sri Lanka and other developing countries in agricultural regions. Although the exact etiology of the disease has not been confirmed, a number of scientific studies have pointed the finger at industrial agriculture, increasingly finding evidence of chronic pesticide exposure in affected populations.   To better understand the connection between agrichemical exposure and kidney health, researchers enrolled 293 individuals from Wilgamuwa, Sri Lanka into a prospective study. Baseline data was retrieved on occupational and environmental exposure factors, focusing in on the water source individuals used at their homes. Samples of each participant’s household wells were taken and analyzed for the presence of pesticides. Of the wells sampled, 68% were found to contain pesticides. Further, every well where pesticides were detected had at least one pesticide recorded above global drinking water guidelines. The chemicals found were also some of the most toxic pesticides to […]

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Pesticides and Parkinson’s Disease: The Toxic Effects of Pesticides on the Brain

Thursday, December 16th, 2021

(Beyond Pesticides, December 16, 2021) A study by Shanghai Jiao Tong University, China, finds Parkinson’s Disease (PD) risk increases with elevated levels of organochlorine (OCP) and organophosphate (OP) pesticides in blood. Among patients with PD, specific organochlorine compounds have greater associations with cognitive impairments, including depression and brain function. Research finds exposure to chemical toxicants, like pesticides, can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, researchers suggest changes in protein enzyme composition and cellular dysfunction from pesticide exposure interrupt normal brain function. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses each year. The disease affects 50% more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While only 10 to 15 percent of PD incidences are genetic, PD is quickly becoming the world’s fastest-growing brain disease. Therefore, research like this highlights the need to examine alternate […]

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Pesticide Exposure Contributes to Preterm Births and Low Birth Weight

Thursday, November 18th, 2021

(Beyond Pesticides, November 18, 2021) A study published by King George’s Medical University, India, finds exposure to xenobiotic substances like pesticides during pregnancy increases risks associated with preterm birth, including a rise in cesarean section (C-section) deliveries and a decrease in fetal body weight. Preterm births occur when a fetus is born early or before 37 weeks of complete gestation. Premature births can result in chronic (long-term) illnesses among infants from lack of proper organ development and even death. Birth and reproductive complications are increasingly common among individuals exposed to environmental toxicants, like pesticides. The Center for Disease Control (CDC) reports the preterm birth rate is increasing annually. Therefore, studies like this can help government and health officials safeguard human health by assessing adverse effects following prevalent chemical exposure. The study notes, “To the best of our knowledge, this was a pioneering study, and it may help to increase our knowledge with regard to xenobiotic exposure in biological systems and the need for stringent guidelines for agricultural use of pesticides.” The study examines the association between the transfer of xenobiotics (foreign synthetic substances like pesticides) from mother to fetus. Transferal of these toxic substances can result in biological and chemical changes (i.e., genotoxicity […]

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Study Identifies the Presence of Organochlorine Pesticides among South China Sea Coral Reefs

Thursday, August 12th, 2021

(Beyond Pesticides, August 12, 2021) A recent study published in Chemosphere identifies the concentration, consequences, and potential sources of 22 organochlorine pesticides (OCPs) among corals in the South China Sea (SCS) for the first time. SCS corals exhibit a higher affinity toward bioaccumulation of OCPs, which are legacy persistent organic pollutants (POPs) under the Stockholm Convention—a global treaty to eliminate POPs. The study finds the distribution of OCPs in coral tissue matches that of the surrounding oceanic air samples. Hence, atmospheric concentrations of OCPs—influenced by continental air masses—migrate from the atmosphere to seawater through gas exchange. Coral reefs are one of the largest ecosystems in the ocean, sustaining marine biodiversity and providing many goods and services. However, living coral populations are rapidly declining due to ocean acidification, oceanic warming, habitat destruction, and pollution from human activity across the globe. From rare corals off the coast of Florida to well-established hard corals in the Great Barrier Reef, these communal organisms are sensitive to various environmental stressors that threaten biodiversity. Although several studies demonstrate the volatile, toxic nature of POPs, much less research evaluates the impact POPs have on biodiversity over time. The globe is currently going through the Holocene Extinction, Earth’s 6th mass extinction, with one million species of plants and […]

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