(Beyond Pesticides, January 31, 2023) Glyphosate exposure induces oxidative stress in the body, a key biomarker known to heighten an individual’s risk of cancer, according to research published in the Journal of the National Cancer Institute by a team of scientists from the National Institutes of Health. The findings, which tracked study participants’ past use of glyphosate and exposure levels through urine, are particularly concerning in light of recent data showing that four out of five (81.6%) U.S. residents have detectable levels of glyphosate in their bodies. Despite these concerning data, evidence of widespread exposure to a carcinogen has so far failed to sway regulators at the U.S. Environmental Protection Agency, necessitating meaningful change by elected officials to reform pesticide regulation. Scientists began with the determination from the International Agency for Research on Cancer (IARC) that there is epidemiological evidence associating glyphosate with blood cancers like non-Hodgkin lymphoma, and strong evidence of carcinogenicity in laboratory animal research brought on by genotoxicity (DNA damage) and oxidative stress. “Oxidative stress occurs when the production of reactive oxygen species (ROS) and other free radicals exceeds the body’s antioxidant defense mechanisms, causing damage to DNA, proteins, and lipids,” the study explains. This process can […]

(Beyond Pesticides, January 30, 2023) Because antibiotics and fungicides are widely used in agriculture (except organic), they contribute significantly to the increasing efficacy problems with antimicrobial (antibiotic and antifungal medicines) use in health care, contributing to a growing crisis. According to Tedros Adhanom Ghebreyesus, PhD, World Health Organization Director-General, “Antimicrobial resistance undermines modern medicine and puts millions of lives at risk.”  Microorganisms—including bacteria, fungi, and viruses—are notoriously quick to evolve resistance to antimicrobial medicines. We know that selection for resistance is directly related to the frequency and intensity of antimicrobial use, so medical practitioners try to avoid using those medicines unless they are necessary. Tell EPA to cancel all uses of a pesticide when resistance is discovered or predicted to occur. Tell Congress to ensure that EPA protects public health from deadly antifungal and antibiotic resistance. Unfortunately, the medical profession lacks complete control over the use of antimicrobials. Many of the same chemicals used in human medicine are also used in agriculture. These may show up in or on treated food, but can also spread antimicrobial resistance through horizontal gene transfer. So, in addition to ingesting antibiotics in our food, the movement of resistant bacteria and fungi in the environment […]

(Beyond Pesticides, January 27, 2023) The U.S. Department of Agriculture (USDA), through its Agricultural Marketing Service (AMS), announced on January 19 its final rulemaking, the Strengthening Organic Enforcement Rule (SOE). The new requirements aim to strengthen the integrity of the National Organic Program (NOP) through both enhanced oversight and enforcement of existing program regulations, and the introduction of new ones to address occurrences of fraud in organic supply chains. Beyond Pesticides welcomes this important step in increased rigor for the burgeoning organic sector; the organization has long advocated for strong enforcement of the provisions of the 1990 Organic Foods Production Act (OFPA), the statute that gave rise to the NOP. It must also be noted that there is a significant difference between the (appropriate) attention being paid to oversight and enforcement in organic, and the long-standing lack of same in regard to the U.S. Environmental Protection Agency’s (EPA’s) pesticide regulations, weak as they are. Beyond Pesticides Executive Director Jay Feldman commented, “It is difficult to have a balanced conversation about any weaknesses in organic enforcement — which must be strengthened — without assessing the entire food system. The NOP provides the structure and the requirements for compliance with the OFPA. […]

(Beyond Pesticides, January 26, 2023) A study published in Food Safety and Toxicology finds that the widely used fungicide azoxystrobin (AZO), used in food production and turf management, can disrupt the function of the intestinal (colonic) barrier responsible for the absorption of nutrients and defense against harmful substances. This and other similar data are important because the U.S. Environmental Protection Agency (EPA), with its required pesticide testing protocol, says that the chemical has “low acute and chronic toxicity to humans, birds, mammals, and bees,” and speaks to the need for the agency to modernize its registration requirements. [The agency does note that AZO is “is highly toxic to freshwater fish, freshwater invertebrates, and estuarine/marine fish, and very highly toxic to estuarine/marine invertebrates.] AZO is a broad-spectrum chemical used in wheat, barley, oats, rye, soya, cotton, rice, strawberry, peas, beans, onions, and a long list of other vegetables, as well as on lawns and golf courses, on a range of fungal diseases. The intestinal (colonic) barrier prevents the internal environment from damage caused by exogenous toxins to ensure internal homeostasis, impeding incidences of systemic inflammatory response syndrome (SIRS), sepsis, and multiple organ dysfunction syndrome (MODS). The intestines host a group of microorganisms that form […]

(Beyond Pesticides, January 25, 2023) Populations of the western bumblebee are in free fall, with 57% declines across the species’ historical range, finds new research led by scientists at the U.S. Geological Survey. These data are in line with trends for other once common bumblebees in the United States, like the rusty patched and American, of which the former is now listed as endangered and the latter is under consideration. Most critically, the study authors did not simply generalize the most likely and common reasons, but instead establish the contribution that pesticide use, climate change, and land use changes have on western bumblebee declines. As the study shows, both the drivers and solutions to pollinators declines are in human hands, necessitating a broad rethinking of the nation’s approach to energy use and food production. The western bumblebee has been under considerable stress for decades. In the 1990s, there were attempts to commercialize the species as a greenhouse pollinator. This industrial approach resulted in the spread of a fungal disease called Vairimorpha bombi, and captive rearing of the western bumblebee was eventually halted and deemed untenable. These dislocations resulted in local declines of the species in certain regions of U.S. Northwest […]

(Beyond Pesticides, January 24, 2023) Oral arguments begin this week in a lawsuit challenging the U.S. Environmental Protection Agency’s (EPA) approval of the antibiotic streptomycin as a pesticide on citrus crops. Brought forth by a coalition of farmworker, health, and environmental groups, the lawsuit aims to stop the use of a critical medical treatment for agricultural purposes. “Humanity’s dwindling supply of medically effective antibiotics is not worth sacrificing for an industry that has safer alternatives available,” said Drew Toher, community resource and policy director at Beyond Pesticides. “Despite the challenges, we know from the elimination of this material in organic production that we don’t need antibiotics in order to produce a glass of orange juice.”  In 2020, the Lancet published an article that identifies several of the multiple and interacting crises the U.S. and world face, with a focus on another “looming potential pandemic . . . [a] rise in multidrug-resistant bacterial infections that are undetected, undiagnosed, and increasingly untreatable, [whose rise] threatens the health of people in the USA and globally.” It calls on leaders in the U.S. and beyond, asking that even as they address the current coronavirus pandemic, they also attend to the antimicrobial resistance (AMR) problem, […]

(Beyond Pesticides, January 23, 2023) There is no doubt that the climate crisis is upon us. And the consequences are undeniably grave. So, we must incorporate our understanding of the grave health and environmental effects into the deliberations on all policy decisions regarding petrochemical pesticide registrations and synthetic fertilizer use in agriculture and nonagricultural land management. Of critical importance, in this context, is the effect of policy decisions on soil health—in particular, soil organic carbon, which sequesters atmospheric carbon and reduces its damaging atmospheric effects. Tell USDA, EPA, and Congress to incorporate in ALL its policy decisions an analysis of impact on the climate crisis, with particular attention to the protection of soil health. Although the soil is commonly recognized as a sink for atmospheric carbon, there is a false narrative that says carbon can be sequestered in the soil through chemical-intensive no-till agriculture. Now the Rodale Institute’s 40-Year Report on their “Farming Systems Trial” should end the myth of the toxic, petrochemical-based, GMO-herbicide, no-till systems. Rodale’s scientific trials clearly show that these degenerative no-till systems are inferior to Regenerative Organic Agriculture on every key criterion. The highest yields of corn in the tilled organic manure system and the best increases […]

(Beyond Pesticides, January 20, 2023) In late December 2022, the University of California San Francisco made a public apology for the unethical actions of two School of Medicine faculty members who conducted experiments in the 1960s and 1970s on some 2,600 prisoners held at the California Medical Facility at Vacaville. The connection to the work of Beyond Pesticides? The experiments involved exposing male prisoners, by dermal application and via injection, to insecticides and herbicides; this continued until 1977, when the State of California banned all human subject research at state prisons. The investigation and apology — which arose through the work of the UCSF Program for Historical Reconciliation — surface multiple issues surrounding scientific research on human subjects, including ethics and regulations related to consent and to risk of harm. Beyond Pesticides has assiduously chronicled the huge variety of health harms that pesticide use can cause, has reported on many studies evidencing the presence of pesticide residues in human bodies, and in the mid-2000s weighed in on the then-vociferous ethics and regulations controversies surrounding research practices (see more below). UCSF investigated the case of two dermatology professors who, the university learned, had failed to secure consent from the prisoners — […]

(Beyond Pesticides, January 19, 2023) Research published in Environmental Health Perspectives finds the presence of nine various neonicotinoids (neonics) and six neonic metabolites within human cerebrospinal fluid (CSF). CSF is an essential part of the central nervous system (CNS), especially for CNS development. Specific chemical biomarkers (measurable indicators of biological state), like pesticides, found in CSF are useful for diagnosing and evaluating numerous neurological diseases. The nervous system is an integral part of the human body and includes the brain, spinal cord, a vast network of nerves and neurons, all of which are responsible for many of our bodily functions—from sensed to movement. However, mounting evidence over the past years shows that chronic exposure to sublethal (low) levels of pesticides can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. The impacts of pesticides on the nervous system, including the brain, are hazardous, especially for chronically exposed individuals (e.g., farmworkers) or during critical windows of vulnerability and development (e.g., childhood, pregnancy). Researchers identify the role agricultural chemicals play in CNS impacts causing neurological diseases, like amyotrophic lateral sclerosis (ALS) and Parkinson’s disease, dementia-like diseases such as Alzheimer’s, and other effects on cognitive function. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood […]

(Beyond Pesticides, January 18, 2023) Sunflower plantings have the potential to significantly reduce mite infestations in nearby honey bee colonies, according to research recently published in the Journal of Economic Entomology by researchers with the U.S. Department of Agriculture (USDA). With pollinators under threat from pesticides, climate change, loss of habitat, and the spread of disease and parasites, sustainable methods that address multiple factors at once are needed. This study points to a way to address destructive Varroa mites, while reducing the need for in-hive use of miticides that can likewise harm colony health. “If sunflowers are as big of a factor in mite infestation as indicated by our landscape-level correlations … having a few more acres of sunflower within a mile or two of apiaries could bring colonies below the infestation levels that require treatment of hives with acaracides (i.e., mite-controlling chemicals),” said lead author Evan Palmer-Young, PhD, of USDA’s Bee Research Lab in Beltsville, MD. Prior research has pointed to sunflower pollen as a potential benefit for a number of common bee diseases and infestations, including the Varroa mite, the fungal parasites Nosema spp, and various viruses. Investigations went through four different experiments aimed at characterizing any potential […]

(Beyond Pesticides, January 17, 2023) One of the world’s most successful conservation laws—the U.S. Endangered Species Act (ESA)—was enacted in 1973. Since then, it has saved countless imperiled species from extinction, put hundreds more on the road to recovery, and has enabled the preservation of habitats that support all of us. Thanks to the Endangered Species Act, the humpback whale, bald eagle, and snail darter are still with us. The ESA is our most powerful tool to combat the extinction crisis and stem the loss of biodiversity currently facing our country and the global community. However, decades of underfunding have kept it from realizing its full potential. Tell the Biden Administration and Congress to provide adequate funding for the Endangered Species Act. The Biden Administration must significantly increase its budget request for endangered species in FY24. A budget of $841 million for the U.S. Fish and Wildlife Service (FWS) is needed to fully implement the Endangered Species Act. Currently, FWS only receives around 50% of the funding required to properly implement the Act. The money is needed to support the following activities. Listing: FWS needs at least $66.3 million, or an increase of at least $11.3 million per year for at […]

(Beyond Pesticides, January 16, 2023) Martin Luther King, Jr. spoke about individual greatness on February 4, 1968 to his congregation at Ebenezer Baptist Church in Atlanta two months before he was assassinated. We take this day—Monday, January 16— to commemorate the life and work of Martin Luther King, Jr. as an inspiration for taking on the challenges of justice, equity, and safety as a central part of all our work for a sustainable future. It will take the recognition of the greatness that all individuals have within to raise our voices in our communities to stop the toxic petrochemical assault and advance viable solutions that effect a transformation to organic practices and products. In so doing, we will address those who suffer the most harm from petrochemicals—in their production, transportation, use, and disposal. Whether determining our community’s management of public lands, playing fields, and parks, or choosing food grown without toxic chemicals, or creating habitat for biodiversity, we as individuals and collectively are the instruments for effecting meaningful change. This is true whether focused on an individual chemical exposure or in taking on the existential health, biodiversity, and climate crises of our day. Dr. King’s complete quote from which the […]

(Beyond Pesticides, January 13, 2023) The pastoral image that “farming” may still conjure for many will suffer a shock as Beyond Pesticides reports, in this Daily News Blog, about developments in the agricultural universe, including massive consolidation in the industries that supply seeds and agrochemicals to conventional farmers. A January 2023 report from Philip H. Howard, PhD updates previous work of his (see here and here) on these trends during the past couple of decades, and focuses on the most-recent (2018–2022) developments. The net conclusion is that the four largest agrochemical companies — Bayer (Monsanto), BASF, Corteva, and Sinochem (which recently subsumed ChemChina/Syngenta) — are exerting increasing leverage over an agricultural system that concentrates power and wealth, while threatening health, the environment, and access to food. The machinations of these industries for profit, power, market penetration, and privatization of aspects of the natural world are hardly new. The National Sustainable Agriculture Coalition (NSAC) summarizes some aspects of the situation in saying, “Land and seed once belonged to no one and were shared by all, replicating the giving essence of the natural world. Today, these precious resources are tightly controlled and commoditized inputs. The modern U.S. food and agriculture system is designed to […]

(Beyond Pesticides, January 12, 2023) Exposure to certain pesticides among individuals diagnosed with Parkinson’s disease (PD) can increase the risk of symptom progression. According to a study published in Science of the Total Environment, nearly 20 percent of pesticides associated with the onset of PD also increase the risk of faster decline in motor and non-motor function. Several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Past studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the association between PD onset via pesticide exposure patterns, few epidemiologic studies examine the influence pesticides have on worsening motor and non-motor symptoms in PD. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While […]

(Beyond Pesticides, January 11, 2022) Neonicotinoid insecticides can have detrimental effects on liver health, according to research published in the Journal of Hazardous Materials. While this is the first study to investigate how these chemicals harm the liver, there is increasing evidence that neonicotinoids, otherwise notorious for their effects on pollinators and aquatic life, can cause direct harm to human health. As the U.S. Environmental Protection Agency (EPA) continues to protect the pesticide industry from any measure of meaningful regulation around these hazardous products, the job falls to advocates to place pressure on elected officials to make the changes necessary to safeguard long-term health and well-being. Scientists postulated that neonicotinoids are neither metabolized by the liver nor excreted by urine. To test that hypothesis, 201 individuals from a hospital in China were enrolled into a study. Of the enrolled,  81 were cancer patients, and 120 were not. These individuals underwent a procedure called endoscopic retrograde cholangiopancreatography whereby samples of their bile, a fluid produced in the liver, were retrieved and analyzed. Researchers also performed a series of blood tests, measuring a range of biomarkers, including cholesterol, bilirubin, bile acids, white blood cells, platelets, and others. Lastly, scientists determined the amount […]

(Beyond Pesticides, January 10, 2023) Pollinator losses are responsible for reducing the global production of nuts, fruits, and vegetables by 3-5%, and this loss of healthy, nutrient-dense food is resulting in over 425,000 excess deaths each year, according to research published late last year in Environmental Health Perspectives. While the connection between pollination, food production and health is intuitive, the study’s ability to trace how these impacts are directly harming the well-being of people living right now is shocking, and is a clear sign that pollinator losses must be taken seriously and addressed through meaningful action. To those who consider the decline of pollinators to be some vague, amorphous future threat, let this study end that myth. According to researchers, “Today’s estimated health impacts of insufficient pollination would be comparable to other major global risk factors: those attributable to substance use disorders, interpersonal violence, or prostate cancer. Per a United Nations report, 75 percent of the world’s food crops depend at least in part on pollination, with pollinators contributing an estimated $235 to $577 billion to global crop production annually. Pollinator declines are already adversely impacting food production. A 2016 paper by many of the scientists in the current study […]

(Beyond Pesticides, January 9, 2023) The Biden EPA still needs a new vision in order to meet the existential crises in public health, climate change, and biodiversity. The Trump Environmental Protection Agency (EPA) reversed in four years much of the progress made by the EPA in decades. Despite a broad new perspective embodied in President Biden’s Executive Memorandum (EM) Modernizing Regulatory Review issued on his first day in office, the Biden EPA has not adopted a new direction for regulating pesticides. Tell President Biden, EPA, and Congress to adopt a new direction for pesticide regulation. Immediately following his inauguration, President Joe Biden issued the EM, which directs the heads of all executive departments and agencies to produce recommendations for improving and modernizing regulatory review, with a goal of promoting public health and safety, economic growth, social welfare, racial justice, environmental stewardship, human dignity, equity, and the interests of future generations. This EM could reverse the historical trend of status-quo regulatory reviews required by the White House Office of Management and Budget (OMB) that typically support vested economic interests of polluters (e.g., petroleum-based pesticide and fertilizer manufacturers). The President’s EM sets the stage for the adoption of agency policy across government to […]

(Beyond Pesticides, January 6, 2023) Plaintiffs in a recent pesticide lawsuit against the U.S. Environmental Protection Agency (EPA) reprise, in their arguments, a critique proffered repeatedly by Beyond Pesticides: the agency has failed, for many years, to evaluate and regulate endocrine-disrupting pesticides adequately. The suit, according to Progressive Farmer, argues that the 1996 Food Quality Protection Act (FQPA) — legislation that mandated that EPA establish “tolerances” for pesticides in foods and regulate on those bases — required EPA to develop an endocrine disruptor screening program (EDSP) and to implement it by 1999. The litigation goes on to note that “more than twenty-five years after the passage of the FQPA, EPA has yet to implement the EDSP it created and further, has failed to even initiate endocrine testing for approximately 96% of registered pesticides.” Plaintiffs are asking the court, among other requests (see below) to order “EPA to complete all actions required under the FQPA at issue in this case as soon as reasonably practicable, according to a Court-ordered timeline.” Endocrine disruptors are chemicals that can, even at low exposure levels, disrupt normal hormonal (endocrine) function. Endocrine disruptors function by: (1) mimicking the action of a naturally produced hormone, such as estrogen […]

(Beyond Pesticides, January 5, 2022) The use of insecticidal bed nets (IBNs) to prevent mosquito bites in malaria-endemic communities can result in resistance developing in secondary pests like bed bugs, according to research published in Parasites and Vectors. Decreased efficacy against bed bugs and other non-mosquito pests may result in misuse of both mosquito adulticides and bed nets, hampering efforts to stop the spread of malaria and other insect-borne disease. With resistance following a predicable pattern in both disease-transmitting and secondary pests, there is a critical need to embrace safer, nonchemical solutions, including both ecological and structural approaches to pest management. Researchers investigated the efficacy of untreated bed nets along with those treated with the commonly used synthetic pyrethroids deltamethrin and permethrin against both a population of insecticide-susceptible and pyrethroid resistant bed bugs. Insecticidal netting was secured between two glass jars in both an aggregation and blood meal experiment. For the aggregation experiment, fully fed bed bugs were set up to cross through the bed net to reach a darker resting location. With the blood meal experiment, unfed bed bugs were set up to cross the netting to receive a blood meal. Both experiments show the bed nets carrying little […]

(Beyond Pesticides, January 4, 2022) A study published in Environmental Science and Technology finds neonicotinoids (neonics) and their breakdown products (metabolites), like other chemical pesticide compounds, can readily transfer from mother to fetus. The National Health and Nutrition Examination Survey (NHANES) finds U.S. pregnant women experience frequent exposure to environmental pollutants that pose serious health risks to both mother and newborn. Many known pollutants (i.e., heavy metals, polychlorinated biphenyl, and pesticides) are chemicals that can move from the mother to the developing fetus at higher exposure rates. Hence, prenatal exposure to these chemicals may increase the prevalence of birth-related health consequences like natal abnormalities and learning/developmental disabilities. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Moreover, a mother’s pesticide exposure can have a stronger association with health disorders than childhood exposure, and a newborn can still encounter pesticides. Therefore, it is essential to understand how pesticides impact the health and well-being of individuals during critical developmental periods. Beyond Pesticides has covered a variety of pregnancy risks from pesticides and other toxic chemicals, including these in just the last three years: pesticides and children’s sleep disorders; prenatal exposures to a multitude of chemicals; insecticides and childhood leukemia; insecticides and Attention Deficit/Hyperactivity Disorder. The study […]

(Beyond Pesticides, January 3, 2023) The California Department of Pesticide Regulation (DPR) announced new rules that remove existing limits on the use of 1,3-dichloropropene (1,3-D or Telone), allowing Californians to breathe much more 1,3-D than state toxicologists in the Office of Environmental Health Hazard Assessment (OEHHA) say is safe and highlighting the dangers to which farmworkers are routinely exposed. It is outrageous that the state of California and the U.S. Environmental Protection Agency (EPA) would allow farmworkers—whose labor was judged “essential” during the pandemic—to be routinely exposed to highly toxic pesticides, which could be replaced by organic practices. While the state of California describes its action as increasing protection, advocates point to continued use, unacceptable harm, and the availability of alternative organic agricultural production methods that eliminate the use of 1,3-D. Since over a third of the country’s vegetables and three-quarters of the country’s fruits and nuts are grown in California, most people who buy their food in a grocery store have a stake in how food is grown in the state and the impact that it has on those who live and work there. Tell the state of California, U.S. EPA, an the U.S. Congress to cancel the registration […]

(Beyond Pesticides, December 23, 2022—January 3, 2023) To all those who read Beyond Pesticides Daily News or take action with us through our Action of the Week, a healthy and happy holiday season and new year. The Beyond Pesticides staff will be taking a weeklong break to gather with family and friends and renew our spirits as we plan to elevate our voice for change in the new year. As a reader of these pages, you know that Beyond Pesticides puts major effort into tracking the science on pesticides—their health and environmental effects—as well as alternatives to chemical-intensive management with our heavy emphasis on the organic alternative.   Our dedication to making science accessible to laypeople stems from our belief and experience that we are all effective advocates with our families, friends, school districts, parks departments, and the business community reliant on pesticides when we have access to the information necessary to make informed decisions. With this information, we are unrestrained to challenge decisions that are harmful to our families and communities, including our environment, and capable of advancing solutions that support a future that sustains life. And when it comes to alternatives, we are heavily invested in the organic alternative […]

(Beyond Pesticides, December 22, 2022) International health and environmental groups submitted an urgent letter to  the United Nations Food and Agriculture Organization (FAO) late last month demanding “greater transparency and accountability” through termination of the agency’s two-year-old partnership with CropLife International (CLI), a global trade association representing the world’s biggest pesticide manufacturers. Addressed to FAO Deputy Director Beth Bechdol ahead of FAO Council 171 session in Rome and COP15, the letter outlines a unique opportunity for the organization to lead the phaseout of fossil-fuel based food systems and use of agrochemicals while upholding the agency’s responsibility to act in response to conflicts of interest and human rights violations.   The original Letter of Intent (LOI), signed between CLI President and CEO Guilia Di Tommaso and FAO Director-General Qu Dongyu in October 2020, framed the partnership as a means to ensure humanity’s freedom from hunger while advancing Sustainable Development Goals. However, according to PAN Europe Policy Officer Manon Rouby, “While the private sector has been working with FAO for years, this official agreement with CropLife directly threatens FAO’s work on supporting farmers in the transition towards agroecology, while reducing the harms of synthetic pesticides worldwide. With CropLife members being the largest agrichemical […]