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Daily News Blog

Archive for the 'Agriculture' Category


09
Mar

EPA Asked to Deny Proposal To Use a New Not-Registered PFAS Pesticide under “Emergency” Waiver

(Beyond Pesticides, March 9, 2026) Policy and toxicology are slated to collide as the U.S. Environmental Protection Agency (EPA) considers allowing the use of a PFAS pesticide by invoking an emergency waiver process in federal pesticide law. If authorized, EPA’s decision will permit the use of an unregistered pesticide under an emergency waiver provision—in this case an emergency caused by weed resistance to weed killers (herbicides) on the market. EPA is accepting public comments until March 16, 11:59pm EDT. Beyond Pesticides is urging the public to object to EPA approval by writing to EPA and Congress stating that herbicide resistance is not an emergency and PFAS chemicals must not be broadcast in the environment.  The pesticide that is being requested for use is a new not yet registered, herbicide tetflupyrolimet (TFP), which is a PFAS chemical according to the definition of the Organisation for Economic Co-operation and Development (OECD). The fact that the chemical is not registered by EPA means that it has not been reviewed in accordance with all the safety assessments reviewed under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). The states applying for the exemptions under Section 18 of FIFRA—Missouri and Arkansas—claim that there is an emergency requiring the use of TFP because […]

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06
Mar

Farm Bill Strips Protections from Pesticides for Farmers, Consumers, and the Environment

(Beyond Pesticides, March 6, 2026) The Farm Bill—the Farm, Food, and National Security Act of 2026, H.R. 7567—reported out of the Agriculture Committee in the U.S. House of Representatives yesterday strips environmental and public health protections from pesticides, reversing over 90 years of environmental laws adopted by Congress to protect farmers, consumers, and the environment that stretch back to the first Farm Bill in 1933. The Committee rejected the Protect Our Health Amendment, sponsored by Rep. Chellie Pingree (D-ME), which would have ensured that the final bill maintain three core safeguards in current law: (i) Judicial review of chemical manufacturers†failure to warn about pesticide hazards; (ii) Democratic right of local governments in coordination with states to protect residents from pesticide use; and, (iii) Local site-specific action to ensure protection—the safety of air, water, and land from pesticides under numerous environmental statutes. All Republicans and one Democrat (Rep. Adam Gray, D-CA) on the Committee blocked the Pingree amendment. The Agriculture Committee bill adversely affects a wide range of social and conservation issues, including the protection of family farms, food security, environmental and public health, local and state authority, and judicial review, according to a cross-section of groups representing these interests. […]

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06
Mar

North American Birds’ Decline Associated with Agriculture

(Beyond Pesticides, March 6, 2026) Does humanity want to live in a world without birds? This may seem like an extreme question, but a new study in Science concludes that, without changes in human behavior, just such a world may be on the horizon. This would be a tragedy of colossal proportions, not only for the ecosystem services birds provide, but for the meaning of human life and a healthy biosphere. The oldest human-made image of a bird is 40,000 years old. The new study, by Czech environmental scientist François Leroy, PhD, and two colleagues from The Ohio State University, measured local population abundances of 261 North American bird species between 1987 and 2021. They also measured the speeds at which the species’ populations rose or fell. The study was based on data from the North American Breeding Bird Survey, a program of the U.S. Geological Survey in coordination with the Canadian Wildlife Service. This survey involves direct observations of bird populations along roadsides during breeding season. The program was created in the mid-20th century in response to the severe mortalities associated with the use of DDT, highlighted by Rachel Carson in her seminal 1962 work, Silent Spring. In the […]

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04
Mar

Agricultural Pesticide Exposure Heightens Risks of Kidney Cancer in Men and Women, Study Finds

(Beyond Pesticides, March 4, 2026) In the International Journal of Epidemiology, researchers from France assess the risks of kidney cancer with a wide range of agricultural activities and tasks, finding that occupational exposure heightens kidney cancer risk. In studying participants from the French AGRIculture and CANcer cohort (AGRICAN) with incident kidney cancer, elevated risks of disease development between 25-56% are documented for both men and women engaging in agricultural activities. In men, the authors find increased kidney cancer in those “working with rapeseed and sunflowers, and tasks related to other crops such as corn, wheat/barley, beet, and tobacco.” In women, an increased risk is noted for winegrowers and corn growers. “Pesticide use (on fields and/or seeds) was associated, for both sexes, with these crops, showing exposure-response relationships with crop area and work duration,” the researchers state. This study, of a large cohort of agricultural workers, highlights the disproportionate risks of adverse kidney health to farmworkers directly handling pesticides or encountering pesticide residues on recently treated products. According to the World Cancer Research Fund, kidney cancer is the 14th most common cancer worldwide, affecting men more often than women. Kidney cancer incidence and mortality have increased globally, with various causes, such […]

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02
Mar

GOP Farm Bill Goes to Committee Amid Broad Opposition to Provisions that Eliminate Protections from Pesticides

(Beyond Pesticides, March 2, 2026) In advance of deliberations on the Farm Bill tomorrow, March 3, in the Agriculture Committee of the U.S. House of Representatives, opposition to the GOP-proposed legislation has been widely expressed by farm, environmental, consumer, and social justice organizations. The bill, the Farm, Food, and National Security Act of 2026, H.R. 7567, is a dramatic departure from previous Farm Bills going back to the first one in 1933, which began a process of integrated policy to address family farmers’ sustainability, land conservation, energy, climate, and food security. Discarding the traditional bipartisan process used to draft the Farm Bill, the Republican leadership has instead proposed a measure that has garnered across-the-board disapproval, except from those representing the vested interests of chemical companies and agribusiness. In order to uphold fundamental protections from pesticides for farmers, consumers, and the environment, a campaign has emerged to urge U.S. Representatives to support Rep. Pingree’s Protect Our Health Amendment (removes Sections 10205-10207), move to strike Sections 10201-10204 and 102011, and support the No Immunity for Glyphosate Act provisions. Without a comprehensive overhaul, this campaign is urging a vote against the Farm Bill. Central to the GOP Farm Bill, released by the chair of the U.S. House Agriculture […]

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27
Feb

Benefits of U.S. Organic Production Highlighted in Evidence-Based Research that Supports an Expedited Transition

(Beyond Pesticides, February 27, 2026) Researchers at Prairie View A&M University in Texas published in the journal Sustainability a study of organic agricultural systems from 1960 to 2021, concluding that “the outlook for U.S. organic fruit and vegetables is encouraging, supported by expanding consumer demand, government support, and improved conditions for international trade.” While delivering upbeat findings, including health benefits, the study identifies tremendous obstacles to entry into organic farming, including the limited support for alternative pest management and pest control systems in the United States in recent modern history, compared to the assistance provided for highly subsidized, petrochemical-dependent agricultural practices. Public health and environmental advocates continue to advocate for a wholesale transition to organic pest management, including calls for U.S. Representatives and Senators to cosponsor the Opportunities in Organic Act! Study Methodology, Background, and Findings The authors of this literature review arrived at the following conclusions on research trends for human health and environmental impacts of organic systems (for further analysis, the numbers below list citations from their report): “[O]rganic food has been documented to have higher antioxidant capacity, acidity, and phosphorus as well as lower levels of cadmium, pesticides, and other chemicals (18–22). Additionally, organic practices increase the […]

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26
Feb

Women in Agriculture at Elevated Risk of More Aggressive Breast Cancer from Pesticides, Study Finds

(Beyond Pesticides, February 26, 2026) Published in PLOS ONE, research in Brazil “analyzed the impact of occupational/household chronic exposure to pesticides on the clinicopathological profile of breast cancer in rural women from Paraná southwest, a predominantly rural landscape with large pesticide uses,” finding that “pesticide exposure favors the occurrence of more aggressive breast cancer.” The study highlights the disproportionate risks of pesticides to farmworkers, focusing on women, as it compares exposed and unexposed populations and breast cancer tumor/disease characteristics. One of the study authors, Carolina Panis, PhD, discussed her earlier research at the Beyond Pesticides’ 42nd National Forum Series, The Pesticide Threat to Environmental Health: Advancing Holistic Solutions Aligned with Nature. In her previous work, Pesticide exposure and increased breast cancer risk in women population studies, Dr. Panis documents a number of pesticides that “can increase the risk of BC [breast cancer] development through various mutagenic [genetic mutations] and nonmutagenic mechanisms and can act directly as carcinogens or indirectly as biochemical modifiers and hormonal deregulators. The underlying mechanisms include endocrine disruption; genotoxicity; epigenetic changes [changes to gene function without changing DNA]; enhanced cell migration, invasion, and…” more. Dr. Panis and other researchers at the Forum support community-level understanding of the […]

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23
Feb

Congressional Committee Hears Farm Bill March 3; If Passed as Written Will Revoke Protections from Pesticides

(Beyond Pesticides, February 23, 2026) Amid polarization in the U.S. Congress, key legal protections from pesticides will be revoked with passage of the GOP Farm Bill being debated March 3 in the House Agriculture Committee, despite a growing body of science that shows farmers, consumers, and the environment are facing escalating health and safety threats. In this context, grassroots efforts are underway asking Congressional representative to advocate for the removal of Farm Bill, Title X, Subtitle C, Part 1, which contains attacks on foundational protections from pesticides for farmers, consumers, and the environment—and vote against the Farm Bill if those provisions are not removed. As provisions in the GOP Farm Bill (Farm, Food, and National Security Act of 2026, H.R. 7567) that slash protections from pesticides go to a vote in the Agriculture Committee, health and environmental advocates are calling for committee members to remove the weakening section—Section X, Subtitle C, Part 1, on “Regulatory Reform.” At a time when documented adverse effects from pesticide exposure are skyrocketing and sustainable practices have become widely available, the bill is being characterized as a wish-list for the chemical industry. Recent studies demonstrating connections between prenatal and postnatal exposure to pesticides and severe consequences […]

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20
Feb

Advocates Call for Striking Entire Pesticide Section in GOP Farm Bill To Preserve Fundamental Protections

(Beyond Pesticides, February 20, 2026) As pesticides’ adverse effects on human and ecosystem health stack up in the scientific literature, health and environmental groups are focused on striking an entire section of the Republican Farm Bill that will eliminate protections, which have been written into law for generations. The section is Section X, Subtitle C, Part 1 on “Regulatory Reform.” Threatened are policies intended to protect against the diseases and illnesses touching families and communities, including brain and nervous system disorders, birth abnormalities, cancer, developmental and learning disorders, immune and endocrine disruption, reproductive dysfunction, among others. Wildlife, including mammals, bees and other pollinators, fish and other aquatic organisms, birds, and the biota within soil, are adversely affected with reproductive, neurological, endocrine-disruptive, and developmental anomalies, and cancers. (See Pesticide-Induced Diseases Database.) With the urgent threat of a markup of the legislation scheduled to begin on March 3, attention shifted to a newly released Executive Order (EO) that could provide blanket legal protection for the manufacturer of the weed killer glyphosate, Bayer/Monsanto. By activating the Defense Production Act of 1950 and its immunity from lawsuits provision for glyphosate manufacturers, the administration could mandate production of glyphosate as a “national security” concern and provide […]

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19
Feb

Study Shows Soil Carbon Sequestration and Crop Yields Increase Substantially in Organic Farming Systems

(Beyond Pesticides, February 19, 2026) A study published in Scientific Reports highlights the benefits of organic agriculture in comparison to different farming systems over five years on four crops (maize, tomato, faba bean, and potato). “Soil carbon sequestration is a long-time storage of carbon in soil which represents 70% of the carbon in land,” the authors note. “Therefore, the main aim of this study is to investigate the effect of the agricultural practice systems on the soil carbon sequestration and properties, productivity, water consumption, soil carbon sequestration, CO2 emission and cost of some agricultural crops.” As a result, the experiment reveals that, compared to chemical-intensive farming, organic methods enhance soil properties, reduce water consumption, provide higher yields and higher soil carbon sequestration, reduce CO2 emissions, and achieve the highest total net profit for all four crops after five years. Study Importance The topic of food security and sustainable agricultural systems is a crucial one, particularly as environmental degradation escalates. “Recently, organic agricultural systems have drawn much attention as alternative ways to produce food and ensure security in terms of environmental sustainability,” the researchers say, while Beyond Pesticides and organic advocates have been discussing the viability of organic agriculture for decades. […]

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18
Feb

Dietary Exposure of Poultry to Common Pesticide Mixtures Threatens Reproductive Health, Study Finds

(Beyond Pesticides, February 18, 2026) Research finds that widespread agricultural pesticide use increases chronic dietary exposure in poultry and leads to adverse reproductive effects, despite meeting legal residue limits. As published in Poultry Science by researchers in Poland, the study analyzes low-dose exposure of roosters (Gallus gallus domesticus) to the fungicide tebuconazole (TEB), the insecticide imidacloprid (IMI), and the weed killer glyphosate (GLP) individually and in mixtures, with all concentrations at or below the maximum residue limits (MRLs) established by the European Union (EU). “Sub-MRL pesticide exposure impaired male reproductive function, with the most pronounced effects observed following combined treatments,” the authors report. They continue: “[E]xposure resulted in reduced semen quality, decreased fertility and hatchability, and increased embryo mortality, particularly in groups receiving IMI alone or in combination. These functional impairments were accompanied by detectable pesticide residues in reproductive tissues and body fluids, as well as modulation [modification/alteration] of local and systemic immune parameters.” The results of the experiment highlight how combined pesticide exposure, resulting from common use of multiple pesticide active ingredients concurrently, produces “stronger and more persistent reproductive effects than individual compounds, indicating mixture-specific toxicity.” This study is particularly important, as it represents the chronic exposure to MRL-compliant […]

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17
Feb

Lawsuits Against Chemical Companies, Local Pesticide Limits, and Ecosystem Safety Quashed in GOP Farm Bill

(Beyond Pesticides, February 17, 2026) The Ranking Member of the Agriculture Committee in the U.S. House of Representatives, Rep. Angie Craig (D-MN), issued a swift rebuke to the GOP 2026 Farm Bill text unveiled last Friday, saying it would be “’very difficult, if not impossible’ for her to back a GOP-led farm bill because it contains ‘poison pills’ and doesn’t do enough to aid struggling farmers,” according to Politico. She did not specifically point to the key controversial provisions that eliminate three core safeguards that are seen as critical to the health of farmers, consumers and the environment—judicial review of chemical manufacturers’ failure to warn about pesticide hazards, the democratic right of local governments in coordination with states to protect residents from pesticide use, and local site-specific action to ensure the safety of air, water, and land from pesticides. Beyond Pesticides responded with a nationwide action to Tell members of the U.S. House of Representatives to stop provisions in the Farm Bill that shield chemical companies from liability for the harm caused by their products, intrude on local communities’ democratic right to restrict pesticides, and eliminate pesticide restrictions governing clean water, environmental impacts, and endangered species; with a request to support […]

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16
Feb

Draft Farm Bill Attacks Foundational Protections from Pesticides for Farmers, Consumers, and Environment

(Beyond Pesticides, February 16, 2026) The chair of the Agriculture Committee in the U.S. House of Representatives, in releasing the Republican 2026 Farm Bill draft last Friday afternoon, is challenging three core safeguards that are seen as critical to the health of farmers, consumers and the environment—judicial review of chemical manufacturers’ failure to warn about pesticide hazards, the democratic right of local governments in coordination with states to protect residents from pesticide use, and local site-specific action to ensure the safety of air, water, and land from pesticides. The draft Farm bill language in three separate sections: (i) prohibits lawsuits by farmers and consumers harmed by pesticides for which manufacturers failed to provide complete safety warnings (Section 10205); (ii) takes away the authority of local governments to protect residents and the local environment from pesticide use (Section 10206), and; (iii) repeals requirements in numerous federal statutes to protect against local pesticide contamination that could affect waterways, drinking water, federal projects, endangered species, migratory birds, and toxic waste (Section 10207). Beyond Pesticides responded with a nationwide action to Tell members of the U.S. House of Representatives to stop provisions in the Farm Bill that shield chemical companies from liability for the harm caused […]

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13
Feb

Study Identifies Pesticide Residues in Soil as a Main Driver of Adverse Effects to Soil Biodiversity

(Beyond Pesticides, February 13, 2026) In a novel, continent-wide study of soil biodiversity throughout Europe published in Nature, researchers find 70% of the sampled sites contain pesticide residues, which “emerged as the second strongest driver of soil biodiversity patterns after soil properties,” particularly in croplands. As soil biodiversity is key for ecosystem functioning, agricultural and land management practices that safeguard biodiversity are imperative. This study, however, highlights how pesticides alter microbial functions, including phosphorus and nitrogen cycling, and suppress beneficial taxa, such as arbuscular mycorrhizal fungi and bacterivore nematodes, and adds to a wide body of science that links pesticide residues in soil to adverse effects on biodiversity. In analyzing 373 sites across woodlands, grasslands, and croplands in 26 European countries, and examining the effects of 63 pesticides on soil archaea, bacteria, fungi, protists, nematodes, arthropods, and key functional gene groups, the data reveals “organism- and function-specific patterns, emphasizing complex and widespread non-target effects on soil biodiversity.” As the authors state, “[T]o our knowledge, ours is the first study to demonstrate the relative importance of pesticides in comparison to soil properties, ecosystem type and climate at a continental scale.” Study Importance As Kristin Ohlson describes in her book The Soil […]

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10
Feb

Study Finds Pesticide-Free and Organic Fields Promote Arthropod Biodiversity and Natural Pest Management

(Beyond Pesticides, February 10, 2026) Species that are integral to pest management allow for crucial ecosystem services that negate the need for pesticides in agricultural or land management practices. In a study published in Agriculture, Ecosystems & Environment, researchers from France find pesticide-free fields promote carabid beetles and spiders, generalist arthropod predators that consume slugs, aphids, and mites, that in turn support healthy, organic systems. The study findings highlight the importance of utilizing farming practices that promote biodiversity and foster natural enemy populations as a pest management strategy.   “In this study, we assessed the assemblages of emerging and circulating ground-dwelling carabids and spiders during four months in a continuous mosaic of pesticide-free winter-sown crops under contrasted tillage regimes (minimum vs. conventional tillage) and sown flower strips bordering fields,” the authors describe. They continue: “We detected clear patterns, with high in-field carabid and spider overwintering densities than in adjacent flower strips… Our results also demonstrate the key role of pesticide-free fields under minimum tillage, acting both as a high-quality overwintering site for some dominant carabid species and as a source habitat, as several predator species activity-density responded positively to the increased area of minimum tillage fields in the surroundings.” Background […]

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09
Feb

Valentine’s Day Sparks Discussion of Pesticide Hazards and Sustainable Practices in Flower Industry

(Beyond Pesticides, February 9, 2026) Every year during the lead-up to Valentine’s Day, the story of pesticide-intensive practices in the flower industry is told. The hazards of pesticides used in flower production and their resulting residues are well-documented. At the same time, the benefits of flowers to one’s psychological well-being have been studied, with findings that suggest flowers are a positive stimulus for emotional well-being, beyond the beauty that they bring to a home, wedding, office, or hospital room. One scientific study shows that flowers perform a socio-emotional function, while a survey done by the American Society for Horticultural Science finds that, “Consumers consistently reported positive effects of cut flowers on mood, morale, and stress reduction.” People want to share this positivity through the giving of flowers, especially on Valentine’s Day. Despite these benefits, the few studies that have been conducted show elevated pesticide exposure for florists through inhalation and dermal absorption. Beyond Pesticides’ network, recognizing that flowers can be grown with organic practices, is asking EPA and Congress to eliminate pesticide use in flower production and resulting residues, while supporting the transition to organic management practices. Similar to food production, the organization says that health and the environment do not […]

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06
Feb

U.S. Abandons International Collaboration on Existential Health Challenges at Time When Most Needed

(Beyond Pesticides, February 6, 2026) The United States, under Donald Trump’s direction, has withdrawn from 66 international organizations, the most important for health being the United Nations’ World Health Organization (WHO) and the Intergovernmental Panel on Climate Change. International organizations committed to the application of the best available science and policy development via consultation and consensus serve as a vital check against rampant personal and industry nest-feathering at the expense of global health. The Trump administration has removed this check while expanding his and his associates’ self-dealing and dismissing the critical interactions of crises such as climate change and synthetic chemicals. Although Trump announced this move on inauguration day last year, the completion of the process last week puts the stamp of finality on his total abandonment of public health. This in turn threatens the collapse of WHO—and even the U.N.—altogether, which has wide implications for agriculture, particularly pesticide policies, climate action (and inaction), and infectious disease monitoring, including vaccines and pandemic prevention. [See commentary: On Public and Environmental Health and Worldwide Collaboration.] Other U.N. environmental, health, and agricultural organizations on the list are groups focused on forest degradation, freshwater and oceans, mining, minerals, metals, and sustainable development, biodiversity, and ecosystem […]

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05
Feb

Amid Immediate and Chronic Health and Environmental Effects, Drift-Prone Herbicide Slated for Reapproval

[Update on February 9, 2026: In a press release on Friday, February 6, titled “EPA Implements Strongest Protections in Agency History for Over-the-Top Dicamba Use on Cotton and Soybeans for Next Two Growing Seasons,” the U.S. Environmental Protection Agency (EPA) continues to ignore the wide body of science that documents harms from dicamba, as well as the viability of alternative methods, in establishing what the agency is boasting are “the strongest protections in agency history for over-the-top (OTT) dicamba application on dicamba-tolerant cotton and soybean crops” as a direct response to the “strong advocacy of America’s cotton and soybean farmers.” These so-called “strong protections” are described as a way to ensure farmers can access the tools they “need” while also protecting the environment from dicamba’s harmful drift. In using “gold-standard science and radical transparency,” EPA created new label restrictions for the next two growing seasons that include “cutting the amount of dicamba that can be used annually in half, doubling required safety agents, requiring conservation practices to protect endangered species, and restricting applications during high temperatures when exposure and volatility risks increase.” Relying on unenforceable label restrictions and mitigation measures, however, fails to adequately protect health and the environment. See […]

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03
Feb

Pesticide Contamination in Small Water Bodies Threatens Biodiversity and Ecosystem Functioning, Study Finds

(Beyond Pesticides, February 3, 2026) In analyzing the direct and indirect effects of pesticides that act simultaneously upon macrozoobenthos communities (invertebrates living in or on sediment) in standing small water bodies (SWBs) in Germany, researchers find high risks to biodiversity and ecosystem functioning. Published in Hydrobiologia, the experiment finds high risks to invertebrates and highlights how both direct and indirect effects are vital to comprehensive assessments of pesticides. While typically overlooked in regulatory reviews, SWBs are defined as shallow standing or running freshwaters “with a surface area of less than 50 hectares (ha),” such as lakes or ponds, including farm ponds, as well as headwater streams, springs and flushes, and ditches. SWBs are biodiversity hotspots that contribute to numerous ecosystem services and are adversely affected by agricultural land use effects such as pesticide contamination. “Holistic assessments of pesticide effects on invertebrate communities in standing small water bodies have, however, not yet been successful,” the authors note. To address this, the researchers developed an indicator for evaluating pesticide impacts on macrozoobenthos communities, populated with aquatic invertebrates, such as snails, worms, crayfish, and clams, through indirect toxic effects on aquatic plants called INPOND: INdirect Pesticide impacts ON Diversity in standing small water […]

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29
Jan

Neonicotinoid Insecticides Cause Deadly Overheating Behavior in Honey Bees, Study Finds

(Beyond Pesticides, January 29, 2026) A study of ecotoxicity risk from neonicotinoid insecticides, published in Environmental Chemistry and Ecotoxicology, finds that chemicals in this class of pesticides, particularly dinotefuron, increase the body temperature of Apis mellifera (European honey bee) and subsequently accelerate the translocation (movement) of contaminants into hives by the honey bees. The research indicates that neonicotinoids affect acetylcholine receptors in the nervous system, leading to an “elevation in octopamine titer [neurotransmitter/hormone] and subsequent increase in the body temperature of honeybees,” the authors report. They continue: “Furthermore, we observed a considerable upregulation [of] the expression of a flight gene flightin in honeybees. This gene accelerates the homing behavior of honeybees and facilitates the rapid and frequent transport of neonicotinoid pesticide-contaminated nectar to the hive.” In describing their results, the researchers state: “For the first time, we propose that neonicotinoid pesticides accelerate the homing ability of honeybees by affecting their body temperature, which leads to more neonicotinoid pesticides entering the hive and explains the prevalence of neonicotinoids and at higher concentrations in terms of their effects on the honeybee body temperature that enhances homing.” This accelerated movement of neonicotinoid pesticides into honey bee hives heightens the toxicity risks to honey […]

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27
Jan

Widely Used Insecticide in Food Production Triggers Neurological Effects Linked to Parkinson’s Disease

(Beyond Pesticides, January 27, 2026) A three-part study published in Molecular Neurodegeneration draws a connection between Parkinson’s disease (PD) and the organophosphate chlorpyrifos. “Since chlorpyrifos (CPF) exposure has been implicated as a risk factor for PD, we investigated its association to incident PD and if this association is biologically plausible using human, rodent, and zebrafish (ZF) studies,” the researchers state. Together, the three experiments “strongly implicate exposure to CPF as a risk factor for developing PD,” as the authors find that exposure, even at very low concentrations, causes selective toxicity to dopaminergic neurons that are critical for functions of movement, cognition, emotion, and more. The results reveal that in humans, long-term residential exposure is associated with more than a 2.5-fold increased risk of developing PD, while exposure in mice causes “motor impairment, dopaminergic neuron loss, microglial activation, and an increase in pathological α-synuclein (α-syn) [proteins primarily found in the brain].” The researchers continue, “Using ZF, we found that CPF-induced dopaminergic neuron loss was at least partially due to autophagy dysfunction and synuclein accumulation, as knocking down LC3 [a protein chain] recapitulated the dopaminergic neuron loss.” These three studies highlight the association of CPF with increased risks for developing PD, as […]

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23
Jan

Chronic Low-Dose Exposure to Insecticide Chlorpyrifos Reduces Wild Fish Lifespan by Accelerating Aging

(Beyond Pesticides, January 23, 2026) A fish called a lake skygazer (Culter dabryi) shows accelerated aging when exposed to chronic low doses of the insecticide chlorpyrifos, according to a powerful study by researchers from several Chinese institutions, as well as Carleton University in Canada and the University of Notre Dame in Indiana. The study, in Science, finds that chronic low-dose exposures resulting in the accumulation of sublethal effects over time cause deterioration of molecular, cellular, and organ functions that reduce lifespan and fertility. In the study, the fish showed reduced survival in a “dose- and physiological age-dependent manner,” while acute high doses did not have these effects, the authors write. Because the mechanisms researchers focused on are conserved throughout vertebrates, “even low doses of pesticide may pose long-term risks to longevity” in thousands of species, including humans. The regulation of pesticides is based on laboratory animals’ exposure to acute high doses of a chemical–generally measured as the dose that kills half the test animals within 96 hours of exposure. Thus, the assumption that guides the calibration of “safe” or allowable levels of exposure is that lower doses, even if chronic, pose no threat. The current study unambiguously refutes that assumption, […]

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22
Jan

Review Finds Reproductive Toxicity from Neonicotinoid Insecticides, Highlighting Widespread Hazard

(Beyond Pesticides, January 22, 2026) Published in Environmental Research, a review of experimental studies by George Mason University researchers regarding reproductive toxicity of neonicotinoid pesticides (neonics) in rodents finds that all studies “demonstrated negative impacts on male reproductive endpoints in association with neonic exposure, including reduced sperm count, reduced sperm motility, and altered sperm morphology.” These studies highlight how neonics, designed to target insect nervous systems, can affect mammalian systems, representing risks to human health. Criteria for inclusion in the review was restricted to endocrine and/or reproductive outcomes in male rats and mice, leading the authors to analyze 21 studies published between 2005 and 2025. “This narrative review employed a systematic approach and determined that neonics exhibit reproductive toxicity in male rats and mice, particularly impairing testicular function and sperm quality at high exposure levels,” the researchers report. They continue, “Despite species-specific differences, the conserved nature [core mechanism] of reproductive processes across mammals supports the relevance of these findings to human health.” Study Background Neonicotinoids are a class of insecticides that share a common mode of action that affects the central nervous system of insects, resulting in paralysis and death. There is a wide body of science on the effects […]

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