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Daily News Blog

Archive for the 'Antibiotic Resistance' Category


22
Mar

Keep Antibiotics Out of Organic—Keep Organic Strong on Range of Issues; Comment by April 5

(Beyond Pesticides, March 22, 2021) The National Organic Standards Board (NOSB) is receiving written comments from the public through April 5. This precedes the upcoming public hearing on April 20 and 22—concerning how organic food is produced. Also, by April 5, sign up to speak (3 minutes) at the virtual NOSB hearing. Written comments must be submitted through Regulations.gov. As always, there are many important issues on the NOSB agenda this Spring. For a complete discussion, see Keeping Organic Strong and the Spring 2021 issues page. The National Organic Standards Board (NOSB) is considering a petition to allow the antibiotic kasugamycin to be used in organic apple and pear production. Earlier NOSB members struggled long and hard to erase the stigma of antibiotic use in organic fruit production—something that was left over from the transition of so many chemical-intensive fruit orchards after the Alar “scare” in which apple and apple products were contaminated with the cancer-causing plant growth regulator daminozide. Do we now want to step on that treadmill again? The reasons for rejecting the kasugamycin petition are the same as the reasons for eliminating the antibiotics streptomycin and tetracycline in crop production. Now that we have learned what a pandemic […]

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04
Mar

Implications for Human Health: Glyphosate-Related Soil Erosion Re-Releases Toxic Pesticides from Soil

(Beyond Pesticides, March 4, 2021) A new study finds glyphosate use stimulates soil erosion responsible for releasing banned, toxic pesticide chlordecone (Kepone), which was used in banana production. For years, an unknown pollution source continuously contaminated water surrounding islands in the French West Indies (Martinique and Guadeloupe). However, researchers from the University of Savoie Mont Blanc in France have found that chlordecone—extensively used on banana farms from 1972 to 1993—is the contamination culprit. Glyphosate is the most popular herbicide in the world, thus ubiquitous in the environment. Therefore, it is vital to understand the implication glyphosate use has on soil health and the potential re-release of soil-bound, toxic contaminants into the surrounding environment to safeguard human health. Researchers note, “[Chlordecone] fluxes drastically increased when glyphosate use began, leading to widespread ecosystem contamination. As glyphosate is used globally, ecotoxicological risk management strategies should consider how its application affects persistent pesticide storage in soils, transfer dynamics, and widespread contamination.” Conventional pesticide use contaminates soil and their respective Critical Zone (CZ) compartments. These CZ compartments interact between the four main spheres (i.e., hydrosphere, biosphere, lithosphere, and atmosphere) of the Earth to support life. Recent decades demonstrate an increase in soil erosion due to sediment changes […]

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24
Feb

Glyphosate and Other Weed Killers Create Antibiotic Resistant Bacteria in Agricultural Soils

(Beyond Pesticides, February 24, 2021) Soil sprayed with weedkillers glyphosate, glufosinate, or dicamba are likely to contain higher amounts of antibiotic resistant bacteria, according to research published earlier this month in the journal Molecular Biology and Evolution. Each year in the United States, at least 2 million people develop an antibiotic resistant infection, and over 23,000 die. Authors of the study say widespread herbicide use is likely playing a role. “Our results suggest that the use of herbicides could indirectly drive antibiotic resistance evolution in agricultural soil microbiomes, which are repeatedly exposed to herbicides during weed control,” said Ville Friman, PhD of the University of York in the United Kingdom. Scientists began their investigation by looking at changes to soil communities in soil microcosms over the course of a roughly two months. Microcosms were grouped by the herbicide applied, while a control microcosm remained unexposed. Each microcosm had a single herbicide applied at a rate reaching 10 parts per million (ppm) in soil. The researchers replicated each treatment 12 times. Contrary to the pesticide industry’s claim that these chemicals break down quickly and become inert by binding to soil particles, large proportions of the herbicides remained in the soil at […]

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26
Jan

Beyond Pesticides Sues Sargento Foods for Mislabeling Antibiotic Use as Threat of Resistance Looms

(Beyond Pesticides, January 26, 2021) As the world moves toward another pandemic associated with antibiotic resistance, Beyond Pesticides sued Sargento Foods, Inc. for misleading its customers with product label claims of “no antibiotics,” which is false according to the complaint. The lawsuit alleges that Sargento’s cheese products are made with milk from cows raised with antibiotics and that antibiotics can be found in some of the company’s finished food.     The use of antibiotics in agriculture is contributing to a “looming potential pandemic” worldwide, resulting from a “rise in multidrug-resistant bacterial infections that are undetected, underdiagnosed, and increasingly untreatable, [which] threatens the health of people in the USA and globally,” according The Lancet, a prestigious medical journal, in September. The World Health Organization has declared that, “AMR [antimicrobial resistance] is one of the top 10 global public health threats facing humanity.” The primary contributors to AMR identified in the scientific literature are antibiotic uses in agriculture and overuse in medicine.  “This lawsuit is motivated by the urgent need to transition away from practices in agriculture that are dependent on antibiotics, advance organic farm management, and avoid new deadly pandemics,” said Jay Feldman, executive director of Beyond Pesticides. “One way to do this is to […]

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25
Jan

EPA: Reverse Approval of Highly Toxic Insecticide Aldicarb on Oranges

(Beyond Pesticides. January 25, 2021) First registered in 1970 and voluntarily cancelled in 2010, aldicarb (Temik™) was being manufactured in Bhopal, India in 1984 when a leak of a precursor—methyl isocyanate (MIC)—spread over the city, ultimately killing more than 25,000 people and leaving more than 120,000 people who still suffer from severe health problems as a result of their exposure. In 1989, Union Carbide Corporation—the manufacturer of aldicarb at the time—paid $470 million (equivalent to $860 million in 2019) to settle litigation stemming from the disaster. Aldicarb has been allowed by the outgoing Trump EPA for use on oranges. >>Tell EPA to Reverse Approval of Highly Toxic Insecticide Aldicarb! No pesticide epitomizes the “cradle-to-grave” dangers of pesticides better than aldicarb. The disaster in Bhopal was followed by others, including a leak in Institute, WV in 1985 that injured at least 135 people and a 2008 explosion in Institute, WV that killed two and injured at least eight. In use, it has been implicated in poisoning of workers and their children, poisoning deer and other game consuming contaminated seeds, and notably, poisoning food grown in soil treated with the chemical. The effects don’t stop there—aldicarb is also notorious for contaminating groundwater. […]

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22
Jan

Will Biden Reverse Last Minute Trump EPA Approval of the Deadly Insecticide Aldicarb, Previously Cancelled?

(Beyond Pesticides, January 22, 2021) After the past four devastating years, hopes and expectations of the Biden/Harris administration abound among the environmental and public health communities. The ears and eyes of many advocates, as well as those in the agricultural community, are attuned (among myriad candidates) to the fate of the pesticide aldicarb. Although Environmental Protection Agency (EPA) registration of this terribly toxic insecticide was cancelled in 2010, various limited-use reapprovals since then have meant that the compound has found its way to increasing levels of use. On January 12, as another parting shot of midnight rulemaking, Trump’s EPA approved expanded uses (see below). The $64,000 question is whether the new administration will use its authority under the Congressional Review Act — which enables Congress to pass a joint resolution (then signed by the President) to overturn a new federal agency rule and prevent its reissuance in the future — to get this pesticide retired for good. Beyond Pesticides urges President Biden’s EPA to do so. Notably, the Trump administration used the Congressional Review Act to destroy myriad environmental rules when it came into power. This permitting of expanded aldicarb uses fits the pattern. Environmental Health News notes that, as of early […]

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09
Nov

Urgent Action Needed to Prevent Another Pandemic—This Time Due to Bacterial Resistance 

(Beyond Pesticides, November 9, 2020) Now that we have learned what a pandemic looks and feels like, with the astounding levels of infection, hospitalization, and death from COVID-19, we must take serious steps to prevent another pandemic on the horizon—this one tied to bacterial resistance to antibiotics. An important article in The Lancet points to a “looming potential pandemic” resulting from a “rise in multidrug-resistant bacterial infections that are undetected, underdiagnosed, and increasingly untreatable, [which] threatens the health of people in the USA and globally.” Tell your Congressional Representative and Senators it is urgent that the National Action Plan for Combating Antibiotic-Resistant Bacteria be initiated. Two contributors to antimicrobial resistance (AMR) that are being highlighted are in agriculture and use of antibiotics in medicine when not warranted. The misuse of antibiotics in agriculture includes antibiotics used to control certain bacterial diseases in plant agriculture (especially oxytetracycline and streptomycin). While crop uses are important contributors to breeding bacterial resistance, they are small compared to their uses in livestock production. Antibiotics are used largely as additives to animal feed to ward off any potential infections and to promote unnaturally rapid growth (the latter of which translates to higher profits), rather than being used […]

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16
Oct

Scientists Warn of Another Pandemic If Officials Continue to Ignore Explosion of ‘Antimicrobial Resistance’

(Beyond Pesticides, October 16, 2020) The Lancet has published an article that identifies several of the multiple and interacting crises the U.S. and world face, with a focus on another “looming potential pandemic . . . [a] rise in multidrug-resistant bacterial infections that are undetected, undiagnosed, and increasingly untreatable, [whose rise] threatens the health of people in the USA and globally.” It calls on leaders in the U.S. and beyond, asking that even as they address the current coronavirus pandemic, they also attend to the antimicrobial resistance (AMR) problem, which is a growing threat to public health. The co-authors outline a number of strategies for progress on AMR, including banning of medically important antibiotics in agribusiness, and promoting consumer, and supplier and private sector, awareness and action on food choices. Beyond Pesticides endorses these strategies, but insists that a genuine solution would include the transition to organic agriculture, not least for the health benefits it would provide. The introduction to the article adds another crisis layer — the climate emergency — and asserts that any resolutions of these crises will, or will not, unfold in a political context: “The outcome of the U.S. election will have far-reaching consequences for planetary […]

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06
Oct

Pesticide Trade Group Wrote U.S. Government Policy to Undermine International Efforts to Combat Antibiotic Resistance

(Beyond Pesticides, October 6, 2020) Despite the rapid rise of antibiotic resistance in the United States and throughout the world, new documents find the Trump Administration worked on behalf of a chemical industry trade group to weaken international guidelines aimed at slowing the crisis. Emails obtained by the Center for Biological Diversity through the Freedom of Information Act show that officials at the U.S. Department of Agriculture (USDA) worked to downplay the role of industrial agriculture and pesticide use in drug-resistant infections. “From everything we’ve seen, it’s clear that this administration believes rolling back regulations and protecting industry profits is more important than protecting public health,” said Nathan Donley, PhD, senior scientist with the Center for Biological Diversity, to the New York Times (NYT). “But what these emails show is that the Department of Agriculture isn’t just soliciting their input. They’re seeking their approval on what the government’s position should be.” Ray McAllister, PhD, of the pesticide industry trade group Croplife America, sent an email in March of 2018 to U.S. officials, wanting to “make certain” that the United Nation’s (UN) Codex Alimentarius, a set of international guidelines and standards established to protect consumer health, made no mention of how […]

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21
May

Study Finds an Association between Dicamba Use and Increased Risk of Developing Various Cancers

(Beyond Pesticides, May 21, 2020) Use of the herbicide dicamba increases humans’ risk of various acute and chronic cancers, according to research published in the International Journal of Epidemiology by the National Institutes of Health (NIH). Many pesticides are “known or probable” carcinogens (cancer-causing agents), and their widespread use only amplifies chemical hazards, adversely affecting human health. However, past research lacks comprehensive information regarding human health effects associated with long-term pesticide use. This study highlights the significant role that long-term research plays in identifying potential health concerns surrounding registered pesticides, especially as the Environmental Protection Agency (EPA) plans to reaffirm its decision to allow dicamba use on genetically engineered (GE) crops. Nathan Donley, Ph.D., a scientist with the environmental health program at the Center for Biological Diversity, comments: “This sweeping study exposes the terrible human cost of the EPA’s reckless decision to expand the use of dicamba. […]For the EPA to approve widespread use of this poison across much of the country without assuring its safety to people and the environment is an absolute indictment of the agency’s persistent practice of rubber-stamping dangerous pesticides.” Dicamba—a benzoic acid chemical that controls broadleaf weeds—is one of the most widely applied herbicides in corn production. As a result of weed resistant to […]

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01
May

Experts Warn Concentrated Animal Feeding Operations (CAFOs) Could Lead to the Next Pandemic

(Beyond Pesticides, May 1, 2020) As the globe settles in for a long summer of social distancing to prevent the spread of COVID-19, experts warn that concentrated animal feeding operations (CAFOs), more commonly referred to as “factory farms,” are setting the table for the next pandemic. Crowded conditions and prophylactic use of antibiotics, scientists say, are creating an environment ripe for viruses and bacteria to evolve and jump from animal to human populations. The Food and Agriculture Organization of the United Nations said back in 2013, “Livestock health is the weakest link in our global health chain.” Alternatively, organic principles offer an existing federal guideline for ecologically and environmentally viable conditions for agriculture. Michael Greger, M.D., Ph.D., author of Bird Flu: A Virus of Our Own Hatching, explains, “When we overcrowd animals by the thousands, in cramped football-field-size sheds, to lie beak to beak or snout to snout, and there’s stress crippling their immune systems, and there’s ammonia from the decomposing waste burning their lungs, and there’s a lack of fresh air and sunlight — put all these factors together and you have a perfect-storm environment for the emergence and spread of disease.” Dr. Greger notes that the spread of […]

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16
Oct

Organic Poultry Significantly Less Likely than Chemical-Intensive to Contain Antibiotic Resistant Bacteria, But Improvements Still Needed

(Beyond Pesticides, October 16, 2019) Organic poultry is far less likely than conventionally raised meats to contain antibiotic-resistant Salmonella, according to research presented last week at a conference for the Infectious Diseases Society of America. With bacterial resistance to common antibiotics on the rise, in large part due to misuse in agriculture, consumers are looking for the best choice to feed themselves and their families. While researchers did find organic poultry production to result in fewer instances of antibiotic resistance, there are still improvements that must be made in organic to further reduce and ultimately eliminate the threat of bacterial resistance and align organic standards with consumer expectations. “Although contamination of retail poultry was found in both conventionally raised and antibiotic-free samples, our results show that Salmonella in poultry produced without antibiotics – based on packaging claims – were significantly less resistant to antibiotics compared with poultry raised using conventional methods,” said Xin Yin, MPH, lead author of the study and DrPH candidate at Penn State College of Medicine, Hershey, Pennsylvania. “Consumers should read production labels and make informed choices based on the evidence about the risk of poultry contamination with drug-resistant Salmonella.” For the study, researchers analyzed samples conducted […]

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14
May

Take Action: Tell EPA and Congress to Ban Streptomycin and Tetracycline in Crop Production to Protect Medical Uses

(Beyond Pesticides, May 14, 2019) Your voice is needed to stop the use of two specific antibiotics, streptomycin and oxytetracycline, whose uses in agriculture are under EPA review. Thank you to those who, last week, told Congress and EPA to ban antibiotic use in agriculture – to help stop the worldwide crisis in bacterial resistance to antibiotics needed for medical purposes in life-threatening cases. Tell EPA and Congress to Ban Streptomycin and Tetracycline in Agriculture In spite of growing bacterial resistance, these two antibiotics are used for important medical purposes. Tetracycline is used for many common infections of the respiratory tract, sinuses, middle ear, and urinary tract, as well as for anthrax, plague, cholera, and Legionnaire’s disease, though it is used less frequently because of resistance. Streptomycin is used for tuberculosis, tularemia, plague, bacterial endocarditis, brucellosis, and other diseases, but its usefulness is limited by widespread resistance. The unnecessary use of these antibiotics in agriculture must be stopped to protect their efficacy for medical purposes. The good news is that organic management practices do not use these antibiotics in crop production and therefore their use is unnecessary with smart sustainable farming practices.  The EPA docket is accepting comments on these two registrations through Friday, May 17. You can sign […]

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08
May

Take Action: Stop Antibiotic Use in Agriculture and Protect Human Health

` (Beyond Pesticides, May 8, 2019) The spread of antibiotic resistance is a health care crisis of major proportions and requires a moratorium on the use of antibiotics in agriculture. The Centers for Disease Control (CDC) call antibiotic resistance “one of the world’s most pressing public health problems.” Many bacterial infections are becoming resistant to the most commonly prescribed antibiotics, resulting in longer-lasting infections, higher medical expenses, and the need for more expensive or hazardous medications. The development and spread of antibiotic resistance is the inevitable effect of the use of antibiotics. Bacteria evolve quickly, and antibiotics provide strong selection pressure for those strains with genes for resistance. Tell EPA and Congress to save antibiotics for important medical uses and eliminate use as pesticides. In spite of the spread of antibiotic resistance, the antibiotics used in plant agriculture are both important for fighting human disease. Tetracycline is used for many common infections of the respiratory tract, sinuses, middle ear, and urinary tract, as well as for anthrax, plague, cholera, and Legionnaire’s disease, though it is used less frequently because of resistance. Streptomycin is used for tuberculosis, tularemia, plague, bacterial endocarditis, brucellosis, and other diseases, but its usefulness is limited by widespread […]

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25
Apr

Deadly Fungal Infection Raises Concerns about Fungicides Used in Agriculture

(Beyond Pesticides, April 25, 2019) As reported by Mother Jones, the New York Times (NYT) published, on April 6, a distressing report about a deadly fungus that has been advancing steadily across the world during the past five years. Candida auris is an emerging fungal pathogen that threatens those with compromised or immature immune systems, such as infants, the elderly, people taking steroids for autoimmune disorders, diabetics, those undergoing chemotherapy, and even smokers. Nearly half of those who contract a C. auris infection die within 90 days. One of the factors making this fungus so deadly is that it has developed resistance to existing antifungal medicines, with 90% of infections resistant to one drug, and 30% to two or more. As is true for resistant bacteria, culprits in C. auris’s development of resistance may be the overuse of antifungal medications in health care and overreliance on fungicides in agriculture. The Centers for Disease Control and Prevention (CDC) has added C. auris to its list of pathogens considered “urgent threats.” It is an “emerging fungal pathogen,” meaning that the incidence of infection has been increasing across multiple countries since it was first recognized in 2009 in Japan (although a different strain had […]

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14
Jan

Tell Congress to Stop EPA from Allowing Antibiotic Use in Citrus Production

(Beyond Pesticides, January 14, 2019) Tell Congress to stop the Trump administration from opening the floodgates to permit widespread use of antibiotics in citrus production (grapefruits, oranges and tangerines). Despite the building national and international crisis of deadly bacterial resistance to antibiotics, this new allowance would expand on an emergency use decision the Environmental Protection Agency made in 2017. It permits up to 480,000 acres of citrus trees in Florida to be treated with more than 650,000 pounds of streptomycin per year; 23,000 citrus acres in California will likely be treated annually. The World Health Organization has called bacterial resistance “one of the biggest threats to global health, food security, and development today.” Tell your U.S. Senators and Representative to urge EPA to reject the use of antibiotics in food production, including citrus production. The two approved antibacterial chemicals to be used as pesticides in citrus production are streptomycin and oxytetracycline. Their use was permitted by the U.S. Environmental Protection Agency (EPA) under an emergency exemption in May, 2017 for a citrus greening disease caused by the bacterium Candidatus Liberibacter asiaticus (CLas) in Florida citrus crops through December of 2019. The Environmental Protection Agency announced March 15, “EPA is issuing these tolerances without notice and opportunity […]

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10
Jan

Take Action: Stop Antibiotic Use in Citrus Production, Leading to Life-Threatening Illness

(Beyond Pesticides, January 10, 2019) The Trump administration is opening the floodgates to allow widespread use of antibiotics in citrus (grapefruits, oranges and tangerines) production, expanding on an emergency use decision it made in 2017. The public has an opportunity to comment on the widespread use of streptomycin by January 19, 2019. You can comment on the federal government’s public comment page (regulations.gov) by leaving a comment opposing any additional use of antibiotics in food production during a national and international crisis of deadly disease resistance to antibiotics. You can copy Beyond Pesticides’ prepared comment below and add your own concerns. Strikingly, the decision allows for up to 480,000 acres of citrus trees in Florida to be treated with more than 650,000 pounds of streptomycin per year, and 23,000 citrus acres in California will likely be treated annually. The two approved antibacterial chemicals to be used as a pesticide in citrus production are streptomycin and oxytetracycline. These uses were permitted by the U.S. Environmental Protection Agency (EPA) under an emergency exemption in May, 2017, allowing residues of antibiotics in Florida orange juice, for the antibiotics streptomycin and oxytetracycline –allowing their use for a bacterial disease, citrus greening (Candidatus Liberibacter asiaticus (CLas) bacterium that causes Huanglongbing), […]

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02
Jan

Is Your Yoga Mat or Gym Breeding Antibiotic Resistant Bacteria?

(Beyond Pesticides, January 2, 2019) The “indoor microbiome” of yoga studios and other athletic facilities often contain significant levels of antibacterial chemicals like triclosan, which show up in dust and breed antibiotic resistance, according to research published last month in the journal mSystems. Triclosan may be banned from hand soaps, but its continued use in a myriad of other products, from disinfectant sprays to impregnated clothing, yoga mats, and other work-out equipment makes it difficult to avoid this now-ubiquitous chemical. This is a public health concern because these antibacterial or antimicrobial chemicals are link to antibiotic-resistant bacteria. Antibiotic resistance kills over 23,000 people each year, according to the Centers for Disease Control and Prevention (CDC). In addition to the CDC, the World Health Organization has cited this escalating problem as become one of the biggest public health challenges of our time. Many people may suspect their gym or yoga study is not a germ-free location, but attempts to address these germs through antibacterial sprays or impregnated yoga mats and other surfaces, may be exacerbating the issue—doing much more harm than good. The continued detection of triclosan and its impacts at new and unexpected locations are feeding renewed calls for a complete ban on […]

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16
Nov

Pesticide Use Found to Surpass ‘Planetary Boundaries’ for Resistance

(Beyond Pesticides, November 16, 2018) Pesticides and biocides used to control bacterial infections in humans and weeds and pests in agriculture are surpassing ‘planetary boundaries’ within which human civilization can continue to rely on these biocides, according to a review by an international team of scientists working on the Living with Resistance project. While the study reinforces the role of susceptible populations in managing resistance, it fails to distinguish essential differences between antibiotic resistance and resistance to pesticides that is identified by Beyond Pesticides. The study focuses on six different forms of resistance. Researchers looked at antibiotic resistance in gram negative bacteria (such as E. coli, P. aeruginosa, Salmonella) and gram positive bacteria (such as S. aureus, Clostridium) separately, due to their divergent resistance mechanisms. Pesticide resistance was divided among herbicides in general, herbicide resistant crops, insecticides in general, and genetically engineered (GE) crops that produce their own insecticide. Resistance to antibiotics and pesticides are similar in that they are both evolved responses to substances toxic to the organism. However, lumping them together in evaluating their importance to human health and survival does not recognize important differences in context. “Without new approaches, going to hospital in the future will increasingly become […]

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17
Sep

Take Action: Comment by October 4 to Protect Organic Integrity!

(Beyond Pesticides, September 17, 2018) The Fall 2018 NOSB meeting dates have been announced and public comments are due by October 4, 2018. Your comments and participation are critical to the integrity of the organic label. Written comments may be submitted through Regulations.gov  until 11:59 pm ET October 4, 2018. Reservations for in-person and webinar comments close at the same time. The proposals of the National Organic Standards Board (NOSB), as a part of its ongoing review of practices and materials, are published for public comment. On our Keeping Organic Strong page, Beyond Pesticides will be providing the public with a listing and analysis of the issues under consideration of the Board when it meets in Saint Paul, MN on October 24 – 26, 2018. You can view USDA’s announcement of the NOSB’s meeting and proposals here. Issues before the NOSB include materials allowed in organic production as well as some policy issues. Materials are either the subject of petitions or the subject of sunset review (concerning whether to be allowed for another 5 years). To be allowed, materials must have evidence summarized in the proposals that they meet the OFPA requirements of essentiality, no adverse effects on humans and the […]

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21
Nov

Herbicide Caused Antibiotic Resistance Not Regulated

(Beyond Pesticides, November 21, 2017) Both the active and inert ingredients in common herbicides induce antibiotic resistance in human pathogenic bacteria, according to the latest research from New Zealand scientists, published in Microbiology this week.  Previous research from the same team found in 2015 that commercial formulations of Roundup (containing glyphosate and inert ingredients) and Kamba (containing 2,4-D, Dicamba, and inert ingredients) caused antibiotic resistance to develop in Salmonella eterica and Escherichia coli, but this new research drills down into what ingredients in these formulations resulted in the effect. Lead author of the study, Jack Heinemann, PhD, University Canterbury’s School of Biological Sciences, explains that ultimately this research indicates that, “The sub-lethal effects of industrially manufactured chemical products should be considered by regulators when deciding whether the products are safe for their intended use,” Scientists parsed out the effects of individual active and inert ingredients by obtaining pure, technical grade dicamba, 2,4-D, and glyphosate, as well as the inert co-formulants “Tween80” and “CMC,” which are respectively, used to reduce surface tension and regulate the viscosity in a formulated herbicide, though also used as emulsifiers in foods like ice cream and in medicines. The technical grade herbicides were first applied to […]

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12
Jul

Western Australian Researchers Mine Antimalarial Compounds as Potential Herbicides

(Beyond Pesticides, July 12, 2017) In a move that threatens to further the spread of antibiotic resistance, researchers at the University of Western Australia (UWA) mining a collection of antimalarial drugs for potential new herbicides. Joshua Mylne, PhD, a senior lecturer in the School of Molecular Sciences (SMS) who directs the project, got started based on work he did while in the Australian Army Reserve. There he discovered that “malarial parasites are actually closely related to plants.” Due to widespread resistance of weeds to the popular herbicide glyphosate, Dr. Mylne began investigating antimalarial drugs as potential replacements. Malaria parasites are actually protozoans in the genus Plasmodium. Their crucial connection with plants is that the parasite contains a plastid similar to the chloroplast in plants. Like the chloroplast in plants, this plastid is critical for the survival of the parasite. Along with organic chemist Keith Stubbs, PhD, associate professor in SMS, Dr. Mylne began screening chemicals in the “Malaria Box,” an open source collection of potential anti-malarial drugs that have never been commercialized. Of the 20 chemicals tested on the small weed Arabidopsis thaliana, 11 were found to have some herbicidal activity. They were then compared to the herbicides glyphosate, glufosinate, asulam, […]

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