Archive for the 'Chemical Mixtures' Category
13
Nov
(Beyond Pesticides, November 13, 2024) A study in Chemosphere, conducted by researchers from the Institute of Biochemistry and Molecular Biology in Germany, reveals the varied lethal and sublethal effects of different glyphosate mixtures through tests on the South African clawed frog, Xenopus laevis (X. laevis). After exposing embryos to four glyphosate formulations, mortality, morphological defects, altered heartbeat rate, and impaired heart-specific gene expression are observed. Glyphosate, an herbicide and popular weed killer in many Roundup® products, is one of the most commonly detected pesticides in waterbodies worldwide, threatening aquatic organisms and overall biodiversity. This study investigates the effects of Glyphosat TF, Durano TF, Helosate 450 TF, and Kyleo, four formulations containing glyphosate, as compared to the effects of pure glyphosate on embryonic development in amphibians. The formulations consist of varying concentrations of the active ingredient glyphosate, as well as other active and inert ingredients. The authors share that, “Glyphosat TF contains 34% glyphosate and 10–20% d-glucopyranose, while Durano contains 39–44% glyphosate and 1–5% N–N-dimethyl-C12-C14-(even numbered)-alkyl-1-amines. In Helosate most of the ingredients are listed – 50–70% glyphosate, 1–10% isopropylamine, 1–3% lauryl dimethyl betaine, 0.25–1% dodecyl dimethylamine. Kyleo only lists the active ingredients glyphosate (27.9%) and 2,4-D (32%).†2-cell stage embryos (early […]
Posted in 2,4-D, Aquatic Organisms, Biodiversity, Chemical Mixtures, Death, Developmental Disorders, DNA Damage, Endocrine Disruption, Environmental Protection Agency (EPA), Epigenetic, Glyphosate, Herbicides, Pesticide Mixtures, synergistic effects | No Comments »
09
Oct
(Beyond Pesticides, October 9, 2024) An agrichemical industry-funded study published in International Journal of Agricultural Sustainability dissects the development of national organic standards and opportunities that can be applied in expanding the use of “regenerative†agriculture. Not surprisingly, the study authors offer support for integrated pest management (IPM) and reassurance of a rigorous pesticide registration review process before the chemicals are marketed. The study included a survey of five farmers, who farm a total of 100,000 acres, but do not have extensive experience farming organically. For those practicing regenerative organic practices and organic advocates, the bottom line is that the study concludes that a list of criteria that would be needed for regenerative agriculture criteria (e.g., list of allowed substances) already exists within the standards and requirements of the 1990 Organic Foods Production Act (OFPA) and the National Organic Program. Environmental and public health advocates are concerned about this piece representing an industry position being cloaked in an academic journal serving as an obstacle to the widespread adoption and improvement of organic principles and practices. The study was written by four authors with varying levels of connections to CropLife America (the major agrichemical industry trade group), including academic researchers with […]
Posted in Alternatives/Organics, Biodiversity, Chemical Mixtures, Chemicals, Corporations, Federal Agencies, Integrated and Organic Pest Management, National Organic Standards Board/National Organic Program, Pests, Pollinators, soil health, Soil microbiome, Uncategorized | No Comments »
16
Jul
(Beyond Pesticides, July 16, 2024) Yet another study in the August 2024 journal Ecotoxicology and Environmental Safety has found that exposure to organophosphorus pesticides (OPPs) is correlated with increased suicidal thoughts in some people. This study is just the latest in a long line of studies from around the world that have linked pesticide exposure to mental health conditions, including sleep disorders, depression, and suicidal ideation (SI). As the rate of suicide increased by 30% between 2000 and 2020, there is an urgent public health need to investigate and address all potential contributing factors. A 2019 study, covered in Daily News, found that teens and adolescents living in agricultural areas and exposed to organophosphate (OP) insecticides are at higher risk of depression, In July and January this year, other studies link farmer psychiatric episodes to pesticide exposure, adding to the body of science. Exposure to household pesticides is also linked to depression in a 2020 study.  Study and Methodology The study entitled “Association between exposure to organophosphorus pesticide and suicidal ideation among U.S. adults: A population-based study,†analyzes information on the mental and physical health of over 5,000 individuals aged 20 and up in the United States. The study aims […]
Posted in 2,4-D, Agriculture, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention (CDC), Chemical Mixtures, Death, Depression, Disease/Health Effects, Farmworkers, Increased Vulnerability to Diseases from Chemical Exposure, men's health, Occupational Health, organophosphate, Pesticide Mixtures, Suicide, Uncategorized | No Comments »
19
Jun
Calls for Holistic Environmental Justice and a Shift Away from Societal Dependence on Petrochemical Pesticides and Fertilizers (Beyond Pesticides, June 18-19, 2024) Juneteenth (June 19) commemorates the date in 1865 when the enslavement of Black Americans ended in the westernmost Confederate state of Texas, over two and a half years after the Emancipation Proclamation of 1863 and the defeat of the Confederacy on April 9, 1865. On June 19, 1865, Union Major General Gordon Granger brought federal troops to Galveston, Texas and finally, and belatedly, implemented the Emancipation Proclamation, which proclaimed on January 1, 1863 freedom from slavery across the nation. Carl Mack, PhD, a historian and former President of the Seattle-King County NAACP, reminds us that there were still 225,000 enslaved Black Americans in Kentucky and Delaware after June 19, 1865 and the end of the Civil War until December 6, 1865 when Georgia became the 27th state to ratify the 13th amendment. “That is the day in which Georgia ratified the 13th amendment,†Dr. Mack goes on to discuss the remaining three former border states on their progress in adopting the 13th amendment. “As it applies to Delaware and Kentucky, Delaware did not ratify the 13th amendment until […]
Posted in Chemical Mixtures, Disease/Health Effects, Environmental Justice, Environmental Protection Agency (EPA), Pesticide Regulation, Superfund, Take Action, Uncategorized, US Department of Agriculture (USDA) | No Comments »
06
Jun
(Beyond Pesticides, June 6, 2024) Researchers link pesticide exposure to behavioral effects on zebrafish (Danio rerio) larvae, signaling a larger issue for overall population and ecosystem effects. In a study published in Biomedicines, the authors conduct a multi-behavioral evaluation of the effects of three pesticides, both individually and as mixtures, on larvae. As the authors state, “Even at low concentrations, pesticides can negatively affect organisms, altering important behaviors that can have repercussions at the population level.†By analyzing effects on individual zebrafish with single compounds and mixtures, this study shows the dangers of pesticides in aquatic systems regarding synergy (a greater combined effect when substances mix) and the ripples created throughout entire ecosystems. Researchers from the Department of Morphology and Animal Physiology, as well as the Department of Physics, from the Rural Federal University of Pernambuco in Brazil collaborated with the Department of Biology at Indiana University in Indianapolis to perform the study. The researchers exposed zebrafish larvae to carbendazim, fipronil, and sulfentrazone to determine any behavioral effects on anxiety, fear, and spatial/social interaction for each compound separately and in combination. Each compound and mixture were applied to embryo medium, exposing fertilized zebrafish eggs. The embryos of zebrafish hatch, or […]
Posted in Aquatic Organisms, Biodiversity, Carbendazim, Chemical Mixtures, Fipronil, fish, Pesticide Mixtures, synergistic effects | No Comments »
24
May
(Beyond Pesticides, May 24, 2024) Even allegedly “low-toxicity†pesticides such as flupyradifurone (insecticide), azoxystrobin, and difenoconazole (fungicides) pose adverse health effects to solitary ground-nesting squash bees (Xenoglossa pruinose), according to a study published in Biological Sciences. Fungicide exposure led to less pollen collected per flower, while exposure to flupyradifurone (FPF) produced larger offspring (which make it more challenging for them to fly). Simultaneous exposure to the three pesticides “induced hyperactivity in female squash bees relative to both the control and single pesticide exposure, and reduced the number of emerging offspring per nest compared to individual pesticide treatments.†With United Nations Food and Agriculture Organizations-sponsored World Bee Day earlier this week, now more than ever advocates are calling for the elimination of toxic insecticide classes, such as neonicotinoids and butanolides, and their wholesale replacement with organic land management principles. This study was written by Sabrina Rondeau, PhD, postdoctoral Fellow in the Department of Biology at the University of Ottawa, and Nigel E. Raine, PhD, professor at University of Guelph’s School of Environmental Science. Published on March 20, 2024, the researchers delve into the individual and co-exposure impacts of two fungicides and one insecticide, which is important, given the documented synergistic effects […]
Posted in Azoxystrobin, Chemical Mixtures, difenoconazole, flupyradifurone, Fungicides, neonicotinoids, Pollinators, Uncategorized | No Comments »
15
May
(Beyond Pesticides, May 15, 2024) A study published recently in the journal Environmental Research finds a significant correlation between exposure to certain pesticides and an elevated risk of inflammatory bowel disease (IBD), a chronic autoimmune condition of the gastrointestinal tract. The study, adding to the body of science on this subject, evaluates self-reported data from licensed pesticide applicators and their spouses exposed to pesticides for over 20 years. In addition, while some of the chemicals found to be most closely associated with incidents of IBD have been banned from use, they are “forever†chemicals that persist in the environment for generations. These findings demonstrate once again the failings of the current regulatory process to identify hazards before they are put into the environment. The study found evidence that exposure to several organochlorine insecticides (dieldrin, DDT, and toxaphene), as well as organophosphate insecticides (parathion, terbufos, and phorate) and herbicides (2,4,5-T, 2,4,5-TP, and metolachlor), is associated with elevated IBD risk. IBD is a generic term for diseases that result in chronic inflammation of the gastrointestinal tract, such as Crohn’s disease and ulcerative colitis. It is estimated that 6.8 million patients globally suffered from IBD in 2017. IBD may result from an imbalance […]
Posted in Agriculture, Cancer, Carbamates, Cardiovascular Disease, Chemical Mixtures, Chemicals, DDT, Dieldrin, Disease/Health Effects, Environmental Justice, Environmental Protection Agency (EPA), Farmworkers, Glyphosate, Gut Dysbiosis, Herbicides, Inflammatory bowel disease (IBD), Iowa, Lindane, Liver Damage, metabolic syndrome, Metolachlor, Microbiata, Microbiome, North Carolina, organochlorines, organophosphate, Parathion, Phorate, soil health, synergistic effects, terbufos, toxaphene, Uncategorized | 1 Comment »
10
Apr
(Beyond Pesticides, April 10, 2024) Researchers in a 2024 Chemosphere study find synergistic relationships in certain chemical mixtures, particularly heptachlor and triallate and trifluralin and lindane at lower concentrations, respectively. “Investigators should consider additional binary data for acute toxicity and potential chronic health impacts on these mixture…which showed synergism at low levels,†the researchers conclude. “According to a Centers for Disease Control (CDC) assessment, more than 50 pesticides are detected in blood or urine samples from the US population,†Researchers point to a cause for concern. The findings come as no surprise to advocates who have urged an assessment of the potential synergistic impacts of pesticide mixtures in the regulation of pesticides. Researchers “used the exposure data from a complex operating site with legacy pesticide pollution to evaluate if Inhalation of pesticide mixtures released from such contaminated sites could pose a risk to human health, The component-based risk assessment approaches that rely on additivity can predict the actual risk of pesticides in a mixture, and The legacy organochlorine pesticides banned many years ago interact with registered and supposedly safe herbicides in a mixture.†The study site is “a pesticide packaging and handling facility†contaminated with the following pesticides (“historical and […]
Posted in 2,4-D, Chemical Mixtures, contamination, Heptachlor, Lindane, Trifluralin, Uncategorized | No Comments »
12
Mar
(Beyond Pesticides, March 12, 2024) A study released in Science of the Total Environment unpacks the threat of emerging chemicals of concern (CECs), including toxic pesticides, in the groundwater of Tunisia. Researchers highlight that the impact of pesticide drift and leaching into groundwater reserves is not siloed to the Middle East and North Africa (MENA) region, but a key concern for most industrialized countries, including the United States. Authors of this study build on literature of CECs already conducted in the region that have broader implications for the spillover effects of pesticide regulation in broader contexts. This descriptive study and accompanying Environmental Risk Assessment (ERA) demonstrate the urgency of Beyond Pesticides’ mission to ban toxic petrochemical pesticides by 2032 because of the pervasiveness of toxic residues, be it pesticides, antibiotics, or other substances, from groundwater systems to human bodies. The researchers performed the tests in thirteen wells in the Grombalia shallow aquifer, an area of northeast Tunisia that feeds into the Wadi El Bay watershed, which is defined as a “high population density [with] intensive agricultural activity [in ‘one of the most polluted areas in Tunisia’].†The researchers gathered data “during two seasons and were analyzed with two high resolution […]
Posted in Atrazine, Bendiocarb, Carbaryl, Chemical Mixtures, Chemicals, contamination, DEET, Groundwater, Uncategorized, Water | 1 Comment »
09
Jan
(Beyond Pesticides, January 9, 2024) A “landscape-level†study finds that typical risk assessment studies used by the U.S. Environmental Protection Agency (EPA) and European regulators fail to “safeguard bees and other pollinators that support agricultural production and wild plant pollination.â€Â The study, published in Nature (November 2023), evaluates the health of bumble bees (Bombus terrestris) as a sentinel species placed in 106 agricultural landscapes across Europe. The authors’ conclusions challenge “the current assumption of pesticide regulation—that chemicals that individually pass laboratory tests and semifield trials are considered environmentally benignâ€â€”calling into question EPA’s persistent failure to adequately regulate mixtures of chemicals to which organisms are exposed in the real world. This study adds to the body of science on pesticide mixtures adversely affecting bee and pollinator health. See here, here, and here. The failure to capture real-world exposure to pesticide mixtures in its regulatory assessments extends to EPA’s systemic failure to evaluate a range of serious adverse impacts, as noted by the agency’s Office of Inspector General (OIG) report. And, aquatic environments also have documented mixtures of pesticides, with the U.S. Geological Survey finding 90 percent of water samples containing at least five or more different pesticides. “We can take no comfort […]
Posted in Agriculture, Chemical Mixtures, Environmental Protection Agency (EPA), International, Pollinators, Uncategorized, Wildlife/Endangered Sp. | No Comments »
