Archive for the 'Chemicals' Category
21
Oct
(Beyond Pesticides, October 21, 2025) A study, published in International Journal of Hygiene and Environmental Health, calculates cumulative dietary pesticide exposure and finds a significant positive association between pesticide residues in food and urine when analyzing over 40 produce types. The research uses data for 1,837 individuals from the 2015â2016 National Health and Nutrition Examination Survey (NHANES) and compares them to biomonitoring samples of the participants. According to the researchers, âHere we show that consumption of fruits and vegetables, weighted by pesticide load, is associated with increasing levels of urinary pesticide biomarkers.â They continue, âWhen excluding potatoes, consumption of fruits and vegetables weighted by pesticide contamination was associated with higher levels of urinary pesticide biomarkers for organophosphate, pyrethroid, and neonicotinoid insecticides.â The NHANES data is derived from a national biomonitoring survey from the U.S. Centers for Disease Control and Prevention (CDC), which collects information about consumption of fruits and vegetables as well as urine samples. Background As the study authors explain: âHundreds of millions of pounds of synthetic pesticide active ingredients are used every year in the United States, and pesticide exposure can occur through food, drinking water, residential proximity to agricultural spraying, household pesticide use, and occupational use. Pesticide […]
Posted in Agriculture, Alternatives/Organics, Azoxystrobin, Biomonitoring, Body Burden, boscalid, Centers for Disease Control and Prevention (CDC), fludioxonil, Imidacloprid, neonicotinoids, organophosphate, Pesticide Mixtures, Pesticide Regulation, Pesticide Residues, pyraclostrobin, pyrethroids, synergistic effects, Synthetic Pyrethroid, thiabendazole | No Comments »
20
Oct
(Beyond Pesticides, October 20, 2025) With the release of a study that links the use of nitrogen fertilizer in combination with antibiotic pesticides to escalating bacterial resistance, public health advocates are renewing their call for the U.S. Environmental Protection Agency (EPA) and the U.S. Congress to eliminate antibiotic pesticide use in land management. This action comes on the heels of a World Health Organization (WHO) study finding that antibiotic resistance is evolving even faster than previously thought. WHO finds, âOne in six laboratory-confirmed bacterial infections causing common infections in people worldwide in 2023 were resistant to antibiotic treatments. . .. Between 2018 and 2023, antibiotic resistance rose in over 40% of the pathogen-antibiotic combinations monitored, with an average annual increase of 5â15%.â These findings, linking pesticides, antibiotics, and nitrogen fertilizers to antibiotic resistance, again raise serious concerns about the deadly impacts of conventional (chemical-intensive) agricultural practices on human health. The researchers found that nitrogen is a strong driver of resistance processes. The richness and diversity of phagesâviruses that attack bacteria and can transmit antibiotic resistance genes (ARGs)âis highest in the groups exposed to both nitrogen and combined pesticides, and the abundance of ARGs in phages becomes âmarkedly elevatedâ in those same exposure conditions. Bacterial […]
Posted in Agriculture, Antibacterial, Antibiotic Resistance, Antimicrobial, oxytetracycline, streptomycin, Take Action, Uncategorized | No Comments »
16
Oct
(Beyond Pesticides, October 16, 2025) An important new study links pesticides, antibiotics, and nitrogen fertilizers to the extreme global crisis of antibiotic resistance, raising serious concerns about the adverse impacts of conventional (chemical-intensive) agricultural practices. The research team, from several Chinese universities and laboratories and Queenâs University in Belfast, conducted a three-year study in China using soil bacteria and phages (bacteriophages, or viruses that invade bacteria) from an experimental field, exposing them to a variety of conditions ranging from the control (no exposures) to various combinations of nitrogen fertilizer and two categories of pesticides (the insecticide chlorpyrifos and a blend of the fungicides azoxystrobin and propiconazole). Phages are viruses that eat bacteria. They invade the bacterial cell and, in various ways, cause the death of the bacterium. Some viral genes cause the cells to lyse, or dissolve, releasing their genetic material into the surrounding environment, where other organisms can pick up new genes. In this way, phages are a major pipeline for horizontal gene transfer (movement of genes in bacteria from one bacterial species to another) among microbes. This phenomenon is of increasing concern because the genes circulating in this marketplace include many that enhance antibiotic resistance. The researchers were […]
Posted in Agriculture, Antibiotic, Antibiotic Resistance, Synthetic Fertilizer, Uncategorized | No Comments »
15
Oct
(Beyond Pesticides, October 15, 2025) The latest Scientific Investigations Report for 2025 from the U.S. Geological Survey (USGS), entitled âNational Water Quality Program: Multidecadal Change in Pesticide Concentrations Relative to Human Health Benchmarks in the Nationâs Groundwater,â finds moderate concentrations of five pesticides, with the highest percentages in agricultural wells, and concentrations of the carcinogenic soil fumigant DBCP (1,2-dibromo-3-chloropropane), which also causes infertility, that are greater than the maximum containment level, despite being banned over 45 years ago. These results highlight the persistence of pesticides used in agriculture and the elevated risks of pesticide contamination in agricultural areas. This report monitors concentrations of pesticides in well networks across the U.S. in decadal intervals, with this last one incorporating data ranging from 1993-2023. Additionally, DBCP in one well network in the San Joaquin-Tulare River Basin in California continues to be assessed due to previous levels exceeding the human health benchmark (HHB) established by the U.S. Environmental Protection Agency (EPA). The limitations of the study are disclosed in the text of the report. As the authors state: âOnly pesticides with an HHB were included in the multidecadal pesticide change analysis… The total number of pesticides included in this study is less than […]
Posted in Agriculture, Alachlor, Atrazine, California, contamination, DBCP, deethylatrazine, Drinking Water, Groundwater, Pesticide Mixtures, Prometon, simazine, synergistic effects, U.S. Geological Survey, Water | 1 Comment »
07
Oct
(Beyond Pesticides, October 7, 2025) Published in Environment International, a study utilizing silicone wristbands provides a snapshot of chemical exposure in over 600 participants across 10 European countries. Using the wristbands as passive and noninvasive samplers, the researchers find that organic farmersâ wristbands contain lower pesticide levels than other groups, offering insight into the benefits of organic and disproportionate risks to farmers using chemical-intensive methods. The results further reveal prevalent environmental pesticide mixtures, in addition to highlighting exposure to current-use pesticides (CUPs) and legacy (banned) pesticides that occurs through multiple exposure routes to workers, residents, and consumers. âOur study offers a comprehensive analysis of non-dietary pesticide exposure patterns among various populations across the EU [European Union], underscoring its widespread prevalence and identifying significant occupational and residential predictors,â the authors explain. As pesticide exposure occurs through both dietary and nondietary routes, such as through dermal (skin) contact and inhalation of contaminated air, there âis a growing need for aggregated [total; combined] exposure estimates across occupationally and nonoccupationally exposed populations.â The study includes testing for 193 pesticides, both legacy pesticides and CUPs, captured in silicone wristbands worn by farmers, residents living close to treated fields (neighbors), and the general population (consumers) in […]
Posted in Agriculture, Alternatives/Organics, Biomonitoring, Chlorpyrifos, European Union, Farmworkers, Metabolites, Occupational Health, Permethrin, Pesticide Mixtures | No Comments »
02
Oct
(Beyond Pesticides, October 2, 2025) This year marks an advancement of various state-level neonicotinoid laws and regulations, including in Maine, Vermont, and Connecticutâemphasizing surging public support for pesticide reforms. The Maine legislature passed, and Governor Janet Mills (D-ME) signed into law on July 22, 2025, LD 1323, which commissions the Board of Pesticide Control to study the impacts of neonicotinoids and neonicotinoid-treated seeds, which advocates hope will help advance future legislation to prohibit the use, distribution, and sale of neonicotinoid insecticide products. Meanwhile, after years of grassroots advocacy, the Connecticut legislature advanced, and Governor Ned Lamont (D-CT) signed SB 9 into law, which will partially restrict the nonagricultural use of neonicotinoids on turfgrass, starting in 2027. There was a more comprehensive effort that failed to move forward (HB 6916), which would have gone further by restricting or prohibiting the use of neonicotinoids on trees, shrubs, and treated seeds (see here for Beyond Pesticides comments). Maine and Connecticut join eleven other states (California, Nevada, New Jersey, Massachusetts, Maryland, Minnesota, New York, and Vermont) in taking steps to restrict or prohibit the use of neonicotinoids. (See Daily News here.) Whether it is a campaign to ban glyphosate, paraquat, chlorpyrifos, atrazine, or any […]
Posted in Connecticut, Maine, neonicotinoids, Seeds, soil health, State/Local, Uncategorized, Vermont | No Comments »
01
Oct
(Beyond Pesticides, October 1, 2025) A novel study in Scientific Reports combines computational analyses with toxicological data to identify pathways affected by exposure to the weed killer glyphosate. The analyses identify glyphosate targets that correlate with kidney injury and kidney cancer, revealing pathways with significant glyphosate-induced alterations, including the dysregulation of nitrogen metabolism that leads to ammonia accumulation and oxidative stress, both of which contribute to renal (kidney) damage and carcinogenesis (development of cancer). âThis study provides a comprehensive investigation into the molecular mechanisms by which glyphosate may contribute to kidney injury and kidney cancer, employing an array of bioinformatics tools for target prediction, toxicity assessment, pathway enrichment analysis, molecular docking and molecular dynamics simulation,â the researchers state. The results of the analyses and simulations highlight the molecular mechanisms underlying glyphosate’s nephrotoxic (damaging to kidneys) and carcinogenic (cancer-causing) effects. Study Importance and Background Glyphosate, known as a broad-spectrum systemic herbicide, has been used for agricultural and nonagricultural purposes for decades and is the most extensively used herbicide worldwide. This widespread use is largely due to its application to genetically engineered, glyphosate-tolerant crops. Both glyphosate and its main metabolite (breakdown product), aminomethylphosphonic acid (AMPA), are detected in water, soil, and food, […]
Posted in Agriculture, aminomethylphosphonic acid (AMPA), Cancer, Glyphosate, Herbicides, Kidney Damage, Metabolism, Oxidative Stress | No Comments »
30
Sep
(Beyond Pesticides, September 30, 2025)Â A pioneering study has measured the concentrations of pesticides in clouds. Prior to this, rainwater has been tested and found to be a common depositor of pesticides. But there is far less information about the role of clouds themselves. The findings add to general scientific understanding that pesticides go everywhere: into soils, water bodies, and the bodies of plants and animalsâeven when they are not intentionally applied. There are many studies of pesticide concentrations, including their metabolites, so-called âinertâ ingredients, and degradation products, in soil, water and the atmosphere. The study was published in Environmental Science & Technology last August by a team of scientists from the University of Clermont Auvergne and the Laboratoire Phytocontrol in France and the University of Torino in Italy. Clouds are collections of water droplets, as opposed to molecular gases or aerosols, which are simply fine particles or liquid droplets of any substance capable of becoming airborne. Aerosol and gas-phase chemicals are known to travel widely in the atmosphere and do not require the presence of water to do so. Contaminants in rain have been studied to some extent, but rain is a separate analytical category from clouds. A study […]
Posted in Atrazine, Clouds, cypermethrin, DEET, Drift, Fipronil, Metolachlor, rainwater, Tributyltin, Uncategorized, Water | No Comments »
25
Sep
(Beyond Pesticides, September 25, 2025) Reinforcing numerous studies’ findings of widespread environmental contamination with PFAS (per- and polyfluoroalkyl substances), heavy metals, pesticide metabolites, and pharmaceuticals, researchers detected the chemicals in noncommercial backyard eggs laid in Greece, according to a study published in Science of The Total Environment. The researchers found that â[o]nly 9 out of 17 samples were compliant to the limitâŚ.set by the [European Union] for the sum of PFHxS [perfluorohexanesulfonic acid], PFOS [perfluorooctanesulfonic acid], PFOA [perfluorooctanoic acid], and PFNA [perfluorononanoic acid].â They continue: â[A]s regards PFOS, PFHxS, and PFNA, seven, six and one out of 17 samples, respectively, were above the ML (maximum limit) as set by the EU.â With current regulatory standards focused on evaluating exposure to individual chemicals and, in some instances, cumulative risk associated with chemicals that have a common mechanism of effect, this study points out the importance of looking at mixtures of chemicals and the potential synergistic effects. There are some fluorinated pesticides defined as PFAS due to their molecular structure and high toxicity, which makes the chemicals highly persistent in the environment. Center for Food Safety, Center for Biological Diversity, and Public Employees for Environmental Responsibility reviewed the full list of active […]
Posted in European Union, Pesticide Drift, Pesticide Mixtures, Pesticide Regulation, PFAS, Uncategorized | No Comments »
24
Sep
(Beyond Pesticides, September 24, 2025) A novel study of chronic toxicity of the neonicotinoid insecticide thiamethoxam to honey bees (Apis mellifera), published in Insects, finds sublethal effects that threaten the survival of bee larvae and the health of bee colonies. âWe evaluated the effects of thiamethoxam on the entire larval development cycle of reproductive bees and conducted a comparative analysis, demonstrating that thiamethoxam significantly alters ecdysone [a hormone that controls molting in insects] and juvenile hormone titers [hormones for insect growth] in both queen and drone larvae, impairing metamorphosis and reproductive development,â the authors state. Risk assessments and scientific literature focus primarily on honey bee workers, rarely including how pesticides can impact queen and drone bees that are necessary for stable colonies. In focusing on this data gap, the researchers reveal that the survival rate of bee larvae decreases gradually with increasing doses of thiamethoxam, adding to the wide body of science on pesticide-related threats to honey bee health. (See Beyond Pesticidesâ What the Science Shows on Biodiversity page for more information, as well as Daily News coverage on risk assessments here, here, and here.) Honey bees provide crucial ecosystem services as pollinating insects and play a vital role in […]
Posted in Agriculture, Beneficials, Biodiversity, Ecosystem Services, neonicotinoids, Pesticide Residues, Pollinators, Reproductive Health, Thiamethoxam, Wildlife/Endangered Sp. | No Comments »
19
Sep
(Beyond Pesticides, September 19, 2025) In Water Science and Engineering, a study investigating the occurrence and distribution of agricultural pesticides in a riverâlake system of the Taihu Lake Basin in China through surface runoff finds adverse effects on nontarget organisms that threaten ecological security. In evaluating the risks to aquatic organisms, the researchers highlight how pesticide residues in surface water and sediments jeopardize the entire food web, as risks are present throughout multiple trophic levels (positions in the food chain). The results show that in surface waters, the fungicide carbendazim is the dominant pollutant with 23.66% of the contamination. Within the sediment samples, the fungicide tebuconazole is the primary contributor at 28.57%. Overall, fungicides are the main type of pesticide present in the tested river water and sediments. These compounds account for 76.86% and 85.10% of contamination, respectively. The authors also note that pesticide concentrations in both water and sediments in the rivers increase while moving downstream. âEcological risk assessment revealed high mixed risks to algae, daphnia [water fleas], and fish, with risk levels rising along with trophic levels of aquatic organisms,â the researchers state. They continue, â[C]ertain pesticides posed high risks to algae even at low concentrations, indicating more […]
Posted in Agriculture, Aquatic Organisms, Biodiversity, Carbendazim, fish, Fungicides, Imidacloprid, Pesticide Residues, Phorate, Propiconazole, tebuconazole, tetraconazole, Water | No Comments »
18
Sep
(Beyond Pesticides, September 18, 2025) Published in Environmental Toxicology and Pharmacology, a study of earthworms (Eisenia fetida) evaluates the toxicity of environmentally relevant levels of three fluorinated pesticides (fluxapyroxad, fluopyram, and bixafen) through a 56-day soil exposure experiment. The dose- and time-dependent results reveal that effects on growth and reproduction occur at elevated concentrations, with weight loss and reduced offspring occurring from energy depletion and reproductive organ damage. Other implications escalate with concentration as well, including antioxidant system failure and DNA damage. As the authors summarize, âThese findings highlight the mechanisms of fluorine-containing pesticide toxicity in earthworms, emphasizing their potential to disrupt soil ecosystems.â Fluorine-containing pesticides are widely used in agriculture, yet the chronic effects on soil and soil organisms are not fully considered in regulatory review. Research comparing the similarities and differences in the impacts on nontarget organisms from fluorinated pesticides is lacking, with the current study beginning to address the urgent need to close this gap. âData indicate that among more than 100 newly developed pesticides, fluorine-containing pesticides constitute nearly half, making them a focal point in the development of the global pesticide industry,â the researchers state. As representatives of the fluorinated pesticides class, particularly succinate dehydrogenase inhibitors […]
Posted in Agriculture, Beneficials, Biodiversity, DNA Damage, Ecosystem Services, fluopyram, fluxapyroxad, Microbiome, Pesticide Regulation, Reproductive Health, soil health, Soil microbiome | No Comments »
17
Sep
(Beyond Pesticides, September 17, 2025) A study in Environmental Science & Technology finds additive effects of a synthetic pyrethroid insecticide (cypermethrin) and two fungicides (azoxystrobin and prochloraz) on biological control, biomass of major invertebrate trophic groups (position in food web), and soil ecosystem processes in arable systems (land suitable for growing crops). The study authors further highlight the failure of pesticide regulations to consider elaborate trophic interactions and pesticide mixtures, as well as additive and synergistic effects within their assessments, calling attention to the complexity of real-world exposures and the lack of research to fully understand the implications of chemical use for agricultural and land management purposes. âArable systems have a high dependence on diverse natural biota to support pest control, soil bioturbation, and nutrient recycling,â the researchers write. These communities rely on a balance of organisms within various trophic levels in order to function and provide vital ecosystem services. Disruptions caused by environmental contaminants, such as pesticides to nontarget organisms, impact entire ecosystems and overall biodiversity. As the authors state, current risk assessments underestimate the real-world risks of petrochemical pesticides and synthetic fertilizers that, despite a wide body of science connecting exposure to deleterious health and environmental effects, are […]
Posted in Agriculture, Aphids, Azoxystrobin, Beneficials, Biodiversity, Biological Control, cypermethrin, Ecosystem Services, Environmental Protection Agency (EPA), Fungicides, Pesticide Mixtures, synergistic effects, Synthetic Pyrethroid | No Comments »
15
Sep
(Beyond Pesticides, September 15, 2025) With residues of the widely used weed killer glyphosate (Roundupáľá´š) in the food supply long documented, scientific attention has turned to the synergistic effects of the weedkillerâ a magnified effect greater than the individual chemical effects added together. The authors of an article in World’s Poultry Science Journal write, âThe synergistic toxic effects of commercial glyphosate formulations and their bioaccumulation in animal tissues are often overlooked in current safety assessments.â Following up on a previous action, Beyond Pesticides is telling Congress and the U.S. Environmental Protection Agency (EPA) that the agency must consider the effects of pesticides in the context in which they are used and promote the organic alternative. Glyphosate residues in animal feed, as well as in water and through other exposure routes from food generally and residential areas, pose risks to both animal and human health, as these residues can bioaccumulate. As previously examined by Beyond Pesticides, the effects of pesticides are not limited to the crops to which they are applied. Synergistic effects of multiple chemical exposures are the rule, rather than the exception.  With poultry, the herbicide enters the production system through residues in genetically engineered feed. An earlier article in Scientific Reports concludes that glyphosate’s […]
Posted in Agriculture, Environmental Protection Agency (EPA), Glyphosate, Livestock, synergistic effects, Take Action, Uncategorized | No Comments »
12
Sep
(Beyond Pesticides, September 12, 2025) A team of Argentinian researchers conducted a study published in Environmental Toxicology and Pharmacology of the combined effects of the herbicide glyphosate and the pyrethroid insecticide cypermethrin. The researchers observed significantly higher apoptosis in cells exposed to the mixtures than to the individual pesticidesâa synergistic response. Apoptosis, also known as programmed cell death, is a standard way that tissues handle damaged cells to remove threats to their function. The researchers sought to investigate the cellular toxicity of each chemical, individually and in combination, and assessed whether the effects of the mixture were additive or synergistic. Additive effects occur when two individual chemicals amplify the same sort of response, often because the chemicals have similar structures. Synergism can occur when chemicals have different mechanisms of action but work together to create more powerful effects. Mixtures of pesticides are the least-studied area of research conducted for regulatory purposes. While regulators provide instructions to applicators regarding which pesticides can be applied together and combined in tank mixtures, there is no control over how pesticides travel through the environment once applied, as they flow through the air as spray drift, lodge in soils and water, and are incorporated into […]
Posted in Agriculture, apoptosis, cypermethrin, Environmental Protection Agency (EPA), Glyphosate, synergistic effects, Uncategorized | No Comments »
10
Sep
(Beyond Pesticides, September 10, 2025)Â After being criticized by the chemical industry and allied agribusiness and service industry groups on the Make America Healthy Again (MAHA) report in May, the strategy document, released yesterday, has tamped down efforts to reform government programs that regulate pesticides. There are no specific recommendations on improving the regulation of pesticides. Rather, the strategy appears to embrace business-as-usual and could even ramp up government efforts to tout the need for pesticides and claims that current regulatory reviews are effective and comprehensive. In a section of the strategy entitled âIncreasing Public Awareness and Knowledge,â the document says: âEPA, partnering with food and agricultural stakeholders, will work to ensure that the public has awareness and confidence in EPAâs pesticide robust review procedures and how that relates to the limiting of risk for users and the general public and informs continual improvement.â This is at odds with the earlier MAHA assessment report which identified pesticides as substances of concern that, citing deficiencies in chemical reviews, âmay be neglecting potential synergistic effects and cumulative burdens, thereby missing opportunities to translate cumulative risk assessment into the clinical environment in meaningful ways.â While the earlier report, Make Our Children Healthy Again: Assessment, […]
Posted in Agriculture, and Rodenticide Act (FIFRA), Announcements, Atrazine, Chemical Mixtures, Chemicals, Children, Children/Schools, Chlorpyrifos, Clean Water Act, Corporations, Environmental Protection Agency (EPA), Farmworkers, Federal Insecticide, Fungicide, Glyphosate, Groundwater, Label Claims, Pesticide Mixtures, Pesticide Regulation, Reflection, synergistic effects, Uncategorized, US Department of Agriculture (USDA), Water, Water Regulation | No Comments »
09
Sep
(Beyond Pesticides, September 9, 2025) SprayDays California, the pesticide notification and mapping tool run by the California Department of Pesticide Regulation (DPR), was updated in late August after public backlash (including from farmworkers), which identified inadequate notice of pesticide use to those who work in or live in proximity to agricultural fields. According to a DPR press release from August 28, these changes include attempts to bring down barriers for users so that, in the words of DPR Director Karen Morrison, the department can âprovide Californians with access to information and services.â While public health advocates view notification as a step that may allow people to leave a treatment area or take shelter to reduce exposure, groups continue to express concerns about a focus on notification to the exclusion of addressing the root causes of exposureâchemical-intensive agriculture, despite the viability of organic compatible practices and products. The groups criticize the continuous registration of pesticide active ingredients and product formulations without considering widely available practices and nonchemical and nature-based alternatives to pest management. These include regenerative organic principles and practices that draw inspiration from Indigenous land management and agroecological systems that have thrived in coexistence with nature. Recent Updates There are […]
Posted in 1, 3-dichloropropene, 1-3D, Alternatives/Organics, California, Driscollâs, Environmental Justice, Environmental Protection Agency (EPA), Farmworkers, Pesticide Drift, State/Local, Uncategorized | No Comments »
08
Sep
(Beyond Pesticides, September 8, 2025) Beyond Pesticides today called on Congress to require the U.S. Environmental Protection Agency (EPA) to incorporate real world science into its evaluation of pesticide safety calculations by recognizing that daily exposure involves multiple chemicals and synergistic interactionsâ a magnified effect greater than the individual chemical effects added together. The organization cites numerous scientific studies that call public attention to this issue; that a realistic assessment of the human and environmental harm potentially caused by pesticides cannot be evaluated based on single-chemical, single-species tests. Given the numerous complexities associated with this type of assessment, the group points to organic land management in agriculture and residential areas as a more cost-effective approach, sending this message to Congress: EPA must consider the effects of pesticides in the context in which they are used and with reference to the organic alternative. A recent study, covered by Beyond Pesticides in its Daily News, found that the presence of Varroa mites in combination with the neonicotinoid insecticide imidacloprid increases the risk of bee mortality and disrupts the larval gut microbiome. The study found synergy (a greater combined effect) between Varroa destructor, a parasitic mite that attacks and feeds on honey bees, and imidacloprid. The findings were published last […]
Posted in Agriculture, Environmental Protection Agency (EPA), esfenvalerate, Imidacloprid, Increased Vulnerability to Diseases from Chemical Exposure, Pollinators, synergistic effects, Take Action, Uncategorized | No Comments »
05
Sep
(Beyond Pesticides, September 5, 2025) A study in Journal of Agricultural and Food Chemistry finds permethrin, a commonly used synthetic pyrethroid insecticide, to be disruptive to the gut microbiome, altering microbiota and leading to increased formation of fat cells (adipogenesis) and metabolic disorders. With an aim to âcomprehensively elucidate the effects of permethrin on gut microbiota, lipogenesis, and the associated molecular mechanisms,â the study explores the adverse effects of permethrin exposure in adult mice through multiple experiments. âOur study provides the first in vivo [in a living organism] evidence suggesting a potentially causal relationship between permethrin exposure and the development of obesity, potentially mediated by specific gut microbiota-derived metabolites,â the researchers explain. They continue, âNotably, this work is the first to define a distinct microbiotaâmetaboliteâhost axis as a critical mediator of environmental toxicant-induced metabolic dysfunction.â Permethrin is widely used as an insecticide on crops, such as cotton, corn, and wheat, as well as on livestock, in indoor and outdoor areas, and for treating lice and scabies. Mosquito abatement programs often utilize permethrin, further adding to the various exposure routes of this neurotoxic chemical. (See additional uses and health effects of permethrin in Beyond Pesticidesâ Gateway on Pesticide Hazards and Safe […]
Posted in Agriculture, Diabetes, Gut Dysbiosis, Metabolites, Microbiome, Obesity, Permethrin, pyrethroids, Synthetic Pyrethroid | No Comments »
04
Sep
(Beyond Pesticides, September 4, 2025) A review of agricultural neonicotinoid insecticide regulations, published in Pest Management Science, evaluates the varied approaches being taken for bans and exemption-based restrictions in the European Union (EU), Canada, and the United States (U.S.). Despite an ever-growing and overwhelming body of science linking neonicotinoids (neonics) to adverse effects on pollinators and other nontarget species, the regulations fall short in protecting the environment and wildlife. The review, with the history and current status of neonics, lends further support for a full transition to organic agriculture and land management that removes neonicotinoid exposure routes and subsequent health threats. With the application of this widely used class of neurotoxic system insecticides increasing, so too has the concern over the long-term chronic effects on pollinators and other species from exposure. This concern, backed by scientific literature, has âled to increased governmental regulations since the mid-2010s, particularly in agricultural settings,â state the authors from Iowa State University and Washington State University. They continue, âThese regulations have varied in terms of approach, geography, and timeline, starting with a ban implemented by the European Union (EU) and evolving into exemption-based regulations across two Canadian provinces and five U.S. states as of this […]
Posted in acetamiprid, Agriculture, Alternatives/Organics, Beneficials, Biodiversity, California, Canada, Clothianidin, dinotefuron, Environmental Protection Agency (EPA), European Union, Illinois, Imidacloprid, Minnesota, neonicotinoids, New York, Pollinators, Quebec, Rhode Island, thiacloprid, Thiamethoxam, Vermont | No Comments »
02
Sep
(Beyond Pesticides, September 2, 2025) It did not go without notice to U.S. grassroots environmental and public health advocates that earlier this month, over two million people in France signed a âfirst of its kindâ petition that ultimately prevented the overturning of the countryâs ban on bee-killing neonicotinoid insecticides. The action was widely covered in France, including in Le Monde. This uprising, organized by 23-year-old French masterâs student Eleonore Pattery, emphasizes the importance of individuals in communities mobilizing people to protect the planet from pesticides that are having a devastating adverse effect on health and the environment. The grassroots push in France taps into a deep public concern about health and the environment that is emblematic of the level of public engagement needed to thwart the high level of chemical industry, agribusiness, and allied corporate influence that undermines basic protections. Industry interests have long been embedded in federal environmental and public health laws. For example, federal and state pesticide laws (the Federal Insecticide, Fungicide, and Rodenticide Act and similar state laws) allow widespread exposure to toxic chemicals despite the availability of nontoxic alternatives that are both efficacious and cost-effective. Without public engagement, as seen in France, significant improvements in law are constantly […]
Posted in acetamiprid, Alternatives/Organics, European Union, International, neonicotinoids, Pesticide Regulation, Uncategorized | No Comments »
28
Aug
(Beyond Pesticides, August 28, 2025) The U.S. Environmental Protection Agency (EPA) on August 12, 2025, released a statement, âEPA Announces Action to Protect Endangered Species from Insecticide Methomyl,â in which the agency announced label changes for methomyl, a carbamate insecticide, with mitigation measures that are being criticized as allowing great risks to biodiversity and human health. The label changes, following the National Marine Fisheries Serviceâs (NMFS) final biological opinion issued on January 1, 2024, actually establish mitigation measures to be determined by applicators using the Bulletins Live! Two website prior to use. EPA claims that this grower determined action will meet the standards of the Endangered Species Act (ESA) by âreduc[ing] runoff and spray drift from treated areas into speciesâ habitats.â However, the process does not include monitoring and oversight to determine whether the rigorous standards of ESA are being met. The agency says that mitigation tracking is âat the field or farm level,â but it is not required to be submitted to the agency. EPA announced on August 20 that it is holding a 90-minute public webinar on September 16, 2025, at 2:00 PM ET to provide information on the ecological runoff/erosion and spray drift mitigation measures that can […]
Posted in Agriculture, Aquatic Organisms, Biodiversity, Carbamates, Cardiovascular Disease, Drinking Water, Endangered Species Act (ESA), Environmental Protection Agency (EPA), Methomyl, Oxidative Stress, Pesticide Regulation, Water, Wildlife/Endangered Sp. | 1 Comment »
26
Aug
(Beyond Pesticides, August 26, 2025) A scientific review in Worldâs Poultry Science Journal highlights the adverse health effects on avian species from exposure to the widely used weed killer glyphosate (Roundupáľá´š) throughout the process of poultry production. The herbicide enters the poultry production system through residues in genetically engineered feed. An earlier article in Scientific Reports concludes that glyphosateâs (GLP) âwidespread application on feed crops leaves residues in the feed,â while residues are âfound to be common in conventional eggs acquired from grocery stores.â In analyzing the biochemical, toxicological, and ecological impacts of glyphosate on poultry, particularly chickens, the authors find a wide body of evidence linking glyphosate and its metabolite (breakdown product) aminomethylphosphonic acid (AMPA) to debilitating hazards that extend beyond mortality. These sublethal effects include disruption of the gut microbiome and gastrointestinal disease; decreased productivity and diminished reproductive health; hepatic and kidney toxicity; growth and developmental impacts, including teratogenicity and embryotoxicity; endocrine disruption and oxidative stress; and impaired immune functions. The effects of glyphosate, as have long been documented in the scientific literature and covered by Beyond Pesticides here, range from negative impacts on biodiversity and the environment to food safety risks and human health implications. Residues of […]
Posted in aminomethylphosphonic acid (AMPA), Birds, Cancer, contamination, Developmental Disorders, Endocrine Disruption, Genetic Engineering, Glyphosate, Herbicides, Intestinal Damage, Livestock, Microbiome, Oxidative Stress, Pesticide Residues, Reproductive Health | No Comments »