(Beyond Pesticides, December 17, 2024) A systematic review of studies on pesticides as endocrine-disrupting chemicals (EDCs) on body weight, published in Biomedicines, evaluates 36 clinical and preclinical studies and links their agricultural use to obesity. The authors, with the lead researchers from the School of Medicine and Health Sciences at Catholic University of Valencia San Vincente, Valencia, Spain, assess studies on a range of pesticides, including organophosphates, pyrethroids, neonicotinoids, and others. In addition to concluding that the EDCs promote obesity, they report that the chemicals cause “other anthropometric changes by altering lipid and glucose metabolism, modifying genes, or altering hormone levels such as leptin.” Endocrine disruption and obesity are public health concerns, and there is a wide body of science linking pesticide exposure to these effects (see more here). “Obesity is considered to be a worldwide pandemic that leads to an increase in medical costs and thus becomes a public health problem,” the researchers share. They continue, “[Obesity] is also associated with the increased production of environmental chemicals, also called environmental obesogens, used mainly in agriculture, as disease vector control, helping to prevent harmful effects caused by fungi, bacteria, or even pests, using pesticides, insecticides, and herbicides, or endocrine disruptors […]

(Beyond Pesticides, December 12, 2024) A literature review of 161 articles in Discover Toxicology finds that pesticides with different mechanisms of action cause memory and learning impairments. These effects are noted in nontarget species including humans. Pesticide “[e]xposure during development, as well as chronic environmental and occupational exposure, can contribute to decreased cognitive performance,” the researchers say. With a focus on organophosphate pesticides, synthetic pyrethroids, and neonicotinoid insecticides, the authors highlight neurological impacts. Both learning and memory are crucial for the survival of many species. “Considering the importance of learning and memory for human and non-human animal behavior and the growing association between pesticide exposure and cognitive impairment, the aim of this review was to describe the studies showing the impact of pesticide exposure on memory and learning abilities in nontarget species, providing evidence of the impact of pesticides in central nervous system function,” the researchers state. The 161 articles included in the review were identified through database searches in PubMed/Medline and Scielo. The authors note, “Inclusion criteria for article selection included all articles published in English between 2015 and 2024 containing original studies in animals or humans with single or multiple pesticides exposure.” The articles consist of 132 preclinical […]

(Beyond Pesticides, November 19, 2024) Researchers at Stanford University recently published a study in Cancer, an international interdisciplinary journal of the American Cancer Society (ACS), that reveals a correlation for numerous pesticides with increased prostate cancer occurrence and associated death. The study finds that exposure to 22 pesticides is positively associated with prostate cancer. The 22 pesticides include 2,4‐D, acephate, azoxystrobin, bifenthrin, carbaryl, chloropicrin, cloransulam‐methyl, cyhalothrin‐lambda, diflufenzopyr, diuron, glyphosate, hexazinone, linuron, methyl parathion, pendimethalin, propiconazole, sulfosate, thiamethoxam, thifensulfuron, tribenuron methyl, trifloxystrobin, and trifluralin. (See more on 2,4-D and cancer prevalence here and here.) As prostate cancer is a leading national health concern, the authors investigate agricultural pesticide exposure and compared it to prostate cancer incidence and mortality across counties in the contiguous U.S. “The geographic variation in prostate cancer incidence and mortality suggests that regional environmental factors, such as pesticide exposure, may contribute to the development of prostate cancer,” the researchers postulate. In comparing county‐level associations of 295 pesticides and prostate cancer reports, the authors were able to conduct an environment‐wide association study (EWAS) to determine any statistically significant links. “We acquired annual estimated total usage data (kg per county) for all pesticides reported and applied to agricultural crops grown […]

(Beyond Pesticides, July 9, 2024) Last month, California cannabis regulators recalled a pesticide-tainted vape, one of the contaminated products identified in a Los Angeles Times investigation. The report reveals that the California Department of Cannabis Control (DCC) has for months been aware of the presence of dangerous chemicals in legal cannabis sold to the public. Conducted by Los Angeles Times and WeedWeek, a cannabis industry newsletter, the investigation has uncovered alarming levels of the insecticide chlorfenapyr in legal cannabis products sold in state dispensaries. According to an article via the National Institutes of Health, “Although [chlorfenapyr] has been identified as a moderately toxic pesticide by the World Health Organization (WHO), the mortality rate of poisoned patients is extremely high. There is no specific antidote for chlorfenapyr poisoning.” The chemical is associated with adverse liver effects and is toxic to bees, birds, and aquatic organisms. Despite claims that the state’s cannabis is safe and regulated, many popular brands of vapes and pre-rolled joints were found to contain dangerous pesticides at levels exceeding state limits and federal standards for tobacco. This investigation comes on the heels of the discovery of large amounts of illegal Chinese pesticides at cannabis grow operations around the state. […]

(Beyond Pesticides, June 12, 2024) A study of pesticide contaminated algae finds that the disruption of algal communities has a devastating effect on the health of the aquatic food web. The study findings show that contact with pesticides can result in changes to “algal physiology, causing tissue injury, developmental delay, genotoxicity, procreative disruption, and tissue biomagnification” that alters the dominance of algae species in the environment. This in turn “can impact higher trophic levels and have a domino effect on the aquatic food web. It is possible for biodiversity to disappear, reducing ecosystem stability and resistance to environmental alterations,” the authors state. The study, a worldwide literature review conducted by researchers from India, South Korea, and Saudi Arabia, appears in Aquatic Toxicology.  The health of aquatic ecosystems is at risk with indirect effects on nontarget species from pesticides in the environment. This includes impacts on species of fish, invertebrates, microbial communities, and marine mammals. In explaining the importance of extensively studying effects of pesticides, the researchers note, “Different pesticide classes have different chemical structures, which define their modes of action and affect how they interact with both target and nontarget organisms.” Because of this, the range of effects seen from […]

(Beyond Pesticides, August 23, 2023) Researchers are investigating a cutting-edge method to identify the impact of pesticides on reproductive health—shrinking the wait time from months to weeks. Scientists at the University of California, Davis, are developing a method for identifying harmful chemicals in pesticides with the help of glowing fish. This scientific breakthrough could revolutionize pesticide research and help prevent long-term health problems caused by exposure to these chemicals.  Pesticide exposure can cause acute and long-term health problems for the human endocrine system, the hormone system that regulates many biological processes from reproduction to blood sugar, growth, and more. Beyond Pesticides has written about the connections between EPA-registered pesticides and involuntary abortions, reproductive cancers, pregnancy loss, early-onset puberty, and more.   The American Academy of Pediatrics (AAP) has expressed concern over the limited or missing data regarding the health effects of pesticides and food additives on infants and children, who are more vulnerable to chemical exposures. AAP has identified several compounds as being of particular concern, including bisphenols, which are commonly used in the lining of metal cans; phthalates, which are used in adhesives and plasticizers; nonpersistent pesticides, which have been addressed in a previous AAP policy statement; perfluoroalkyl chemicals (PFCs), […]

(Beyond Pesticides, October 4, 2022) A study published in Environmental Pollution finds pyrethroid insecticides contribute to a secondary source of contamination in water resources. Various pyrethroids, including bifenthrin, are detectable in urban catch basins (storm drains) that collect runoff water before draining into the open environment. There is a lack of information regarding the pesticides’ presence in urban catch basins. However, pesticide contamination in water resources is historically commonplace and widespread throughout U.S. rivers and streams, with at least five different pesticides present in 90 percent of water samples. Moreover, thousands of tons of pesticides not only enter waterways (e.g., rivers, streams, lakes, oceans) around the U.S. through urban catch basins but agricultural and nonagricultural sources as well, contaminating essential drinking water sources, such as surface water and groundwater. Reports like these are essential for determining appropriate regulatory action to protect the human, animal, and environmental health from chemical toxicant contamination, especially if chemical contamination is highly detectable. The study notes, “The high detection frequency of bifenthrin and overall pyrethroid concentrations, especially for particle-bound residues, suggest that underground urban catch basins constitute an important secondary source for extended and widespread contamination of downstream surface waters by pesticides such as pyrethroids in urban […]

(Beyond Pesticides, March 1, 2022) A report by the Independent finds chemical-intensive farming of crops for animal feed puts thousands of endangered species at risk. U.S. farmlands use more than 235 million pounds of pesticide (i.e., herbicides and insecticides) solely for animal feed production, many of which are highly hazardous pesticides (HHPs). Several HHP hazard categories include acutely toxic, chronic health hazards, and environmental hazards. Therefore, animal feed production intensifies global pollution, increases pesticide exposure, and degrades human, animal, and ecological health.  Although the report demonstrates a need to eliminate toxic pesticide use for the sake of human, animal, and ecosystem health, it will take more than eliminating the worst chemicals to address the impending biodiversity collapse and the climate crisis. Experts highlight the need for an urgent shift to organic land and agricultural management practices. The study notes, “These pesticides are taking a toll on our environment and biodiversity. Endangered species like the highly imperiled whooping crane, monarch butterflies, all species of salmon, the rusty-patched bumble bee, the San Joaquin kit fox, and the northern long-eared bat, as examples, all face significant threats from industrial agricultural operations and the chemicals applied. In order to conserve biodiversity and better protect vulnerable species and their habitats, […]

(Beyond Pesticides, January 4, 2021) Chronic exposure to pesticides used in conventional forestry operations runoff and harm soft shell clams, according to a recent study published in Science of the Total Environment, entitled “The silence of the clams: Forestry registered pesticides as multiple stressors on soft-shell clams.” Rather than focusing on the impact of a single chemical, researchers analyzed the combined effects of several pesticides. “This is an important data gap to fill as research on these compounds’ toxicity typically focuses on individual compound effects at high concentrations to determine lethality, which while necessary for understanding compound toxicity, can miss sublethal effects that can have long term impacts on these systems,” said lead author Allie Tissot of Portland State University. The soft shell clam, Mya arenaria, is found to be widespread in coastal areas in both the western and eastern U.S., and is often eaten in stews or chowders. A recent study found a range of chemical contaminants detected in Oregon populations of these species, prompting researchers to further investigate the impact of these exposures. An experiment was set up with tanks to mimic a seabed, and eight different groups of 11 clams were established and treated with various amount […]

(Beyond Pesticides, September 22, 2021) Health and environmental organizations are urging the U.S. Environmental Protection Agency (EPA) and state pesticide regulators to immediately stop the use and sale of dangerous and misbranded Eco-MIGHT and W.O.W. (Whack Out Weeds!) products, falsely labeled as 25(b) minimum risk. Recent laboratory testing by the state of California found the presence of hazardous pesticides, including glyphosate, bifenthrin, permethrin, cypermethrin, and carbaryl in these products. “From organic farmers to municipal landscapers and home gardeners, consumers employing minimum risk products are working intentionally to avoid the dangers associated with toxic pesticide exposure,” said Jay Feldman, executive director of Beyond Pesticides. “It is critical that EPA and state regulators coordinate to ensure the integrity of the minimum risk program.” Coordination is critical yet reports indicate that EPA is falling down on the job. The issue first came to light in late July, when the California Department of Food and Agriculture’s (CDFA) State Organic Program issued a Stop Use Notice to farmers alerting them to adultered Eco-MIGHT and W.O.W products. The products make a range of claims, marketed as “organic,” “natural,” “glyphosate-free,” and “non-toxic and safe.” As CDFA Secretary Karen Ross noted, “It is imperative that we alert California […]

(Beyond Pesticides, August 19, 2021) Does a science-based, public health-oriented, occupational safety focused, children-concerned, ecologically protective society allow the use of toxic pesticides that are unnecessary to achieve land management, quality of life, and food productivity goals? Should victims of poisoning have to plead with regulators to protect them? Should organizations have to fight chemical-by-chemical to achieve basic levels of protection from individual neurotoxic, cancer causing, endocrine disrupting pesticides? Of course not. But, the U.S. Environmental Protection Agency’s (EPA) announcement that it is stopping food uses of the insecticide chlorpyrifos after being registered 65 years ago provides us with an important opportunity for reflection, not just celebration. The collective effort to remove this one chemical is a tremendous feat in eliminating one exposure to a hazardous material for children. That is the point. The action we’re celebrating required an amazingly resource-intensive effort at a time in history when we are running against the clock in an urgent race to transition our society and global community away from the use of petroleum-based, toxic pesticides—to move to meaningful practices that sustain, nurture, and regenerate life. In this context, let’s put chlorpyrifos in perspective. EPA was forced into its decision by a court […]

(Beyond Pesticides, July 2, 2020) Exposure to low levels of endocrine-disrupting chemicals commonly in waterways, including pesticides, can impact future generations of major commercial fish, despite no direct exposure to the chemicals, according to research published in the journal Frontiers in Marine Science by Oregon State University (OSU) researchers. Many studies assess the acute or chronic health implications associated with endocrine disruptors on a single generation but lack information on multi-generational impacts that can provide vital information on the fundamental survivability or fitness of many species. This study highlights the significance of understanding the implications of endocrine disruptors, even at low levels of exposure, as parental exposure can have adverse epigenetic consequences for future generations. Kaley Major, a Ph.D. fellow at Oregon State University (OSU) and lead research author, explains, “What t[his] gets at is something your grandparents may have come into contact within their environment can still be affecting the overall structure of your DNA in your life today.” Endocrine disruptors are xenobiotics (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem). Past research shows exposures to endocrine-disrupting chemicals can adversely impact human, animal—and thus environmental—health, by altering the natural hormones in the body responsible for […]

(Beyond Pesticides, December 7, 2018) As medicinal and recreational marijuana continue to be legalized in various states, concerns about the safety of the burgeoning industry — how the substance is grown, harvested, processed, distributed, sold, and used — have emerged. Colorado’s recent experience is a case in point: in early December, the state’s Marijuana Enforcement Division (MED) announced two recalls on cannabis products out of concern about their contamination by pesticide residues. In both cases, the recall announcements from the Colorado Department of Revenue, in conjunction with the Colorado Department of Agriculture (CDA) and the Colorado Department of Public Health and Environment, said that the state agencies “deem it a threat to public health and safety when pesticides that are not on the list of approved pesticides for marijuana use as determined by CDA are applied in a manner inconsistent with the pesticide’s label.” Three off-label pesticides were listed in the recall announcement. Pyriproxyfen was found in samples tested from Colorado Wellness Centers LLC (dba Lush), and bifenthrin and diuron were found in samples from Crossroads Wellness LLC (dba Boulder Botanics). None of those compounds is approved by Colorado for use on marijuana; two are listed as possible carcinogens by […]

(Beyond Pesticides, March 7, 2017) Another study, published by a team of French scientists in the journal Occupational and Environmental Medicine, links childhood behavioral problems to pyrethroid insecticide exposure. Synthetic pyrethroids are a class of insecticides that have increased in use over the past decade due to assumptions that they pose fewer risks to human health than older pesticide chemistries, such as organophosphates. However, this latest study is part of a growing body of research showing that pyrethroids share similar neurocognitive health concerns as these older pesticides. .   In this research, scientists investigate the interplay between pyrethroid exposure and behavioral problems through a longitudinal cohort study, which tracks levels of pyrethroid metabolites, or breakdown products, in the urine of mothers beginning between six and 19 gestational weeks and then in their children up through six years of age. Children’s behavior is measured through a screening questionnaire known as the Strengths and Difficulties Questionnaire (SDQ). SDQ measures how social a child is (altruism), whether the child has difficulty sharing problems or asking for help (internalizing disorders), as well as how defiant or disruptive a child is (externalizing disorders). The study controlled for a number of confounding factors, such as weight, education, location (rural or […]

(Beyond Pesticides, July 18, 2014) After years of struggling to combat the rise of Lyme disease in the region, Loudoun County, Virginia has decided to forgo the spraying of a hazardous pesticide in public parks in favor of public education and continued surveillance of park lands. Controversy over spraying arose back in 2012 when Loudoun began ramping its spray program to manage ticks, often the carrier of the disease. Loudon County used the pesticide Talstar, which contains the active ingredient bifenthrin, a neurotoxic chemical whose use raises public health and product efficacy concerns, as documented by the Centers for Disease Control and Prevention. Beekeepers expressed concern that spraying would greatly damage their bee colonies, as bifenthrin is highly toxic to bees, while conservationists were concerned with the chemicals leaching into waterways and killing aquatic life. At the same time, some researchers point out that there was no evidence that spraying the chemical would reduce the number of Lyme disease infections. After years of debate and data analysis,  David Goodfriend, M.D., M.P.H, director of the Loudoun County Health Department, said that the county’s Lyme Disease Commission’s recommendation was to not spray any of the properties. The recommendation was based on two […]

(Beyond Pesticides, June 9, 2014) A recent talk given by Donald Weston, PhD, a professor emeritus in UC Berkeley’s Department of Integrative Biology, to a community group in San Jose, California warned residents about the dangers that  lawn care insecticides present to  local aquatic life. The talk focused on the problems synthetic pyrethroids and fipronil can have on Hyalella azteca and Chironomus dilutes. Increasing levels of pesticide runoff in local stream systems have not only led to decreased populations of these aquatic crustaceans, but also populations that have become resistant to pesticides. Aquatic invertebrates are extremely sensitive to pesticide runoff and different states around the country have struggled with creating pesticide regulations that foster a healthy aquatic ecosystem. A good way to reduce pesticide runoff is to transition away from toxic land care methods and adopt organic practices. Hyalella crustaceans, a tiny shrimp-like animal, are hypersensitive to pyrethroids, which are a class of insecticides used by professional lawn care companies and found in common products like Raid and mixed with fertilizer products like Scotts Turf Builder under the name SummerGuard. Chironomus dilutes, a red worm-like invertebrate, is sensitive to fipronil, which is used to kill fleas on dogs and cats […]

(Beyond Pesticides, August 26, 2013) A recent study presented by the Centers for Disease Control and Prevention (CDC)   at the International Conference on Lyme Borreliosis and other Tick-Borne Diseases in Boston finds that spraying lawns with the insecticide bifenthrin does not reduce the incidence of tick-borne diseases. The study could have important policy implications for towns and communities that are feeling pressure to spray as prevalence of tick-borne diseases, such as Lyme disease, continue to rise.  There are least-toxic alternative management strategies that are effective and safer than chemical controls. The recently released study by CDC included 2,500 households in Fairfield, Litchfield, and New Haven Counties in Connecticut; Dutchess County in New York; and four counties in Maryland. Half of the households’ lawns were sprayed with bifenthrin and the other half was sprayed with water as a control. The study, conducted over two years, found that the households that were sprayed with bifentrhin saw a 60 percent reduction in ticks on their propriety but still had similar levels of tick encounters and tick-borne illnesses. These final results are similar to the results the study found after its first year.   This research reveals that using pesticides is not an […]

(Beyond Pesticides, June 25, 2013) Traditional Chinese herbs, widely regarded for their medicinal properties, may not be as therapeutic as they seem. In fact, according to a new report released by Greenpeace East Asia, they may be toxic to your health. This news isn’t just disturbing for the Chinese people who live and work around where these toxic herbs are produced, but also for the entire global export market for Chinese alternative medicines, valued at $1.46 billion in 2010. The Greenpeace report found pesticides in 48 out of their 65 samples of traditional Chinese herbs, which included plants such as wolfberries, honeysuckle, the San Qi flower and chrysanthemum. Of these samples, the researchers discovered 51 different kinds of pesticide residues, with 32 of the samples tested containing traces of three or more different pesticides. In 26 samples, residues from pesticides that have been banned for use in agriculture in China were found, including phorate, carbofuran, fipronil, methamidophos, aldicarb and ethoprophos. This report isn’t the first where Chinese exports have been singled out for presence of pesticide contamination. In April 2012, Greenpeace released a report found that Unilever’s Lipton tea bags made in China contain pesticide residues that exceed the  European […]

(Beyond Pesticides, March 26, 2013) Scientists are learning more about the mechanisms bed bugs have developed to increase their resistance to the increasingly common class of pyrethriod pesticides. The study, published in the journal Scientific Reports in early March, adds further weight to calls from consumer health and environmental groups to adopt proven, non-toxic strategies to manage bed bugs and other household pest problems. After all, if alternatives exist, why put your family at risk with unsustainable, ineffective control methods? This latest research reveals something scientists had not suspected. Bed bugs are developing most of their resistance-associated genes on the outer layer of their shell. These genes either neutralize the insecticides before they can take effect, or slow down the toxins’ move towards the insects’ nerve cells. In addition, bed bugs in the study also show resistance developing within their nerve cells, the target site for the pesticides. This multilayered resistance is unique, scientists say, but, as Beyond Pesticides has long documented, pest resistance to pesticides is not. A 2011 study from Ohio State University reveals bed bugs’ ability to evolve hereditary changes in their production of certain enzymes, allowing them to excrete the toxins without being harmed. A study […]

(Beyond Pesticides, May 31, 2012) The Centers for Disease Control and Prevention (CDC) and the Maryland Department of Health and Mental Hygiene have enrolled Maryland households in a study that involves spraying the controversial pesticide bifenthrinon their property to determine the efficacy of this approach in controlling Lyme disease. Now in the beginning of its second year, the study found no evidence in the first year that the spraying works to reduce the transmission of Lyme disease. Beyond Pesticides is concerned that study participants have not been provided complete information about bifenthrin’s potential health risks to people. According to the Baltimore Sun, the study is an effort to find new ways to combat the disease, which infected 1,600 people in Maryland in 2010. Half of the 185 families that have volunteered for the study will have water sprayed on their lawns to serve as a control group, while the other half will receive the bifenthrin treatment. The 185 families that have signed up so far this year get a $25 gift card, lowered from $40 given to the 440 participants last year. Last year, while the pesticide reduced the amount of ticks on treated lawns compared to the control group, […]

(Beyond Pesticides, January 31, 2012) The Environmental Protection Agency (EPA) has proposed an expansion in pyrethrins/pyrethroid insecticide uses as part of its cumulative risk assessment for this neurotoxic class of chemicals. In the cumulative risk assessment, EPA concludes that pyrethroids “do not pose risk concerns for children or adults,” ignoring a wealth of independent data that links this class of chemicals to certain cancers, respiratory and reproductive problems, and the onset of insect resistance. It went as far as to state that its cumulative assessment supports consideration of registering additional new uses of these pesticides, potentially opening the flood gates for manufacturers to bombard the market with more pyrethroid pesticides, endangering the health of the public. The agency is accepting public comments through February 8, 2012. Tell EPA that it has ignored numerous health effects and that these pesticides do pose unacceptable risks to human health given the availability of alternatives. Submit comments directly to the EPA docket or sign-on to Beyond Pesticides’ comments. In its comments to EPA, Beyond Pesticides states: There are several major concerns and flaws plaguing this cumulative assessment, which therefore does not meet the regulatory burden in fully evaluating synthetic pyrethroids’ effect on public and […]

(Beyond Pesticides, December 7, 2011) Aspen City, Colorado, is considering mandating pre-notification of pesticide use so that neighbors and passersby can avoid being exposed to possible toxic chemicals. The notification provides for a 48-hour notice before application, as well as information on the pesticide to be used and its potential health effects. However, the Council stopped short of banning pesticide use outright throughout the city until it could gather additional information on the legal ramification of challenging state preemption law. City Council staff last week requested direction from the Council on whether notification should be required before spraying pesticides, whether minimal restrictions should be imposed on homeowners who spray and whether the city should draft an ordinance that would challenge state preemption laws. Council members are in consensus that the city should move toward mandating pre-notification, and in the meantime continue educational outreach regarding land management practices, which can be more effective than pesticide use. Currently, state law requires pesticide applicators to post notices on properties after they have been sprayed, but not before. While an outright ban would challenge state law, mandating pre-notification would sidestep it. Local governments cannot directly regulate commercial pesticide applicators, but they can regulate homeowners’ […]

(Beyond Pesticides, November 16, 2011) On November 9, 2011, the U.S. Environmental Protection Agency (EPA) issued its cumulative risk assessment for the pyrethroid class of insecticides, concluding that these pesticides “do not pose risk concerns for children or adults,” ignoring a wealth of independent data that links this class of chemicals to certain cancers, respiratory and reproductive problems, and the onset of insect resistance. The agency went as far to state that its cumulative assessment supports consideration of registering additional new uses of these pesticides, potentially opening the flood gates for manufacturers to bombard the market with more pyrethroid pesticides, endangering the health of the public. EPA issued the final pyrethins/pyrethroid cumulative risk assessment in the Federal Register and is requesting comment until January 9, 2011, including information that may be used to further refine the assessment. Pyrethroids are a widely used class of insecticides used for mosquito control and various insects in residential and agricultural settings. However pyrethroids are highly neurotoxic and have been linked to cancer, endocrine disruption, suppression of the immune system, and various reproductive effects. This class of chemicals includes permethrin, bifenthrin, resmethrin, cyfluthrin and scores of others. Read Beyond Pesticides’ factsheet “Syntethic Pyrethroids.” Once the […]