08
Oct
(Beyond Pesticides, October 8, 2024) A comprehensive literature review in Endocrines, published in September, amasses hundreds of studies on endocrine-disrupting chemicals (EDCs) that showcase adverse effects on growth, development, reproduction, and metabolism. The authors, a team of scientists and academics from Brazil, shed light on the link between EDC use and thyroid dysfunction, leading to increasingly prevalent illnesses and deadly diseases.    EDCs are any synthetic or natural compounds that hinder endocrine system functions and create harmful effects on organisms. These chemicals can impact the thyroid gland, which is vital in producing hormones and plays a role in several body functions. As the researchers state, “Several EDCs have been classified as thyroid disruptors, impairing thyroid hormone [TH] production, synthesis, metabolism, transport, and/or actions. Notably, thyroid disorders are the second most prevalent endocrine disease worldwide, with incidence increasing significantly in recent years.” The authors continue, “[S]tudies have correlated this rise in thyroid dysfunctions and cancers with increased exposure to EDCs. Although many EDCs are linked to thyroid dysfunction, this review focuses on the deleterious effects of plasticizers, organochlorine pesticides, and per- and poly-fluoroalkyl substances on thyroid function. These contaminants are commonly found in food, water, and everyday products.” This review helps […]
Posted in Atrazine, Birth defects, Cancer, carbamate, Carbamates, Children, Chlorpyrifos, DDT, Dieldrin, Endocrine Disruption, Endosulfan, Fipronil, mancozeb, organochlorines, organophosphate, Permethrin, PFAS, phthalates, Propiconazole, pyrethroids, Synthetic Pyrethroid, Thyroid Disease, Women's Health | No Comments »
15
May
(Beyond Pesticides, May 15, 2024) A study published recently in the journal Environmental Research finds a significant correlation between exposure to certain pesticides and an elevated risk of inflammatory bowel disease (IBD), a chronic autoimmune condition of the gastrointestinal tract. The study, adding to the body of science on this subject, evaluates self-reported data from licensed pesticide applicators and their spouses exposed to pesticides for over 20 years. In addition, while some of the chemicals found to be most closely associated with incidents of IBD have been banned from use, they are “forever” chemicals that persist in the environment for generations. These findings demonstrate once again the failings of the current regulatory process to identify hazards before they are put into the environment. The study found evidence that exposure to several organochlorine insecticides (dieldrin, DDT, and toxaphene), as well as organophosphate insecticides (parathion, terbufos, and phorate) and herbicides (2,4,5-T, 2,4,5-TP, and metolachlor), is associated with elevated IBD risk. IBD is a generic term for diseases that result in chronic inflammation of the gastrointestinal tract, such as Crohn’s disease and ulcerative colitis. It is estimated that 6.8 million patients globally suffered from IBD in 2017. IBD may result from an imbalance […]
Posted in Agriculture, Cancer, Carbamates, Cardiovascular Disease, Chemical Mixtures, Chemicals, DDT, Dieldrin, Disease/Health Effects, Environmental Justice, Environmental Protection Agency (EPA), Farmworkers, Glyphosate, Gut Dysbiosis, Herbicides, Inflammatory bowel disease (IBD), Iowa, Lindane, Liver Damage, metabolic syndrome, Metolachlor, Microbiata, Microbiome, North Carolina, organochlorines, organophosphate, Parathion, Phorate, soil health, synergistic effects, terbufos, toxaphene, Uncategorized | 1 Comment »
06
May
(Beyond Pesticides, May 6, 2024) The pattern of failure to protect the public from pesticides is again brought to public attention by an analysis by Consumer Reports (CR) that effectively updates its previous report released in 2020. The report and its earlier iteration identify deep structural weaknesses with the institutions charged with protecting the public’s health and safety. The health risks outlined by CR in 2020 and related to ongoing pesticide exposure, even at low levels, include cardiovascular diseases, cancers, reproductive dysfunction, respiratory problems (e.g., asthma, bronchitis), neurological impacts (e.g., developmental effects and dementia/Alzheimer’s), and endocrine dysfunction, among others. Previously, the magazine reported, “CR’s experts say the government hasn’t upheld its responsibility to protect consumers [and that] the research used to set [pesticide residue] tolerances is imperfect, and they’re often too high.” CR has cited the U.S. Environmental Protection Agency (EPA), which is primarily responsible for pesticide regulation, for multiple inadequacies. According to the latest CR analysis, the U.S. Department of Agriculture (USDA) Pesticide Data Program (PDP) Annual Summary has once again failed to accurately portray the safety of some of the most commonly sold fruits and vegetables in the United States. CR reviewed seven years of PDP data, finding that 20% […]
Posted in Agriculture, Alternatives/Organics, Carbamates, Environmental Protection Agency (EPA), organophosphate, Pesticide Residues, Uncategorized, US Department of Agriculture (USDA) | No Comments »
03
May
(Beyond Pesticides, May 3, 2024) Parkinson’s disease (PD) is the second most common neurodegenerative disease in the world after Alzheimer’s. Genetic factors account for only a fraction of PD cases, and for decades scientists have been aware of associations between pesticide exposures and PD. Yet, not everyone exposed to pesticides gets PD. Consequently, neither the genetic nor the environmental hypothesis is fully satisfactory; both may be involved. Thus, there has been great interest in identifying gene variants that affect the risks of PD associated with pesticide exposure. Now a team of University of California at Los Angeles researchers led by neurologist Brent Fogel, MD, PhD has traced a connection between certain gene variants and the occurrence and severity of PD in a cohort of central California PD patients who have had long-term exposure to pesticides. The genes are related to autophagy, the process by which cells organize, degrade, recycle or eject molecules to maintain healthy chemical balance. Autophagy is an essential process throughout the body, including regulation of mitochondria, which are also vital for healthy cellular function. The study supports other research suggesting that autophagy is disturbed in neurodegenerative diseases. As Beyond Pesticides discussed in its April 19 Daily News, PD […]
Posted in arsenic, cacodylic acid, California, Carbamates, Farmworkers, Lewy Body Disease (LBD), Nervous System Effects, organoarsenic, organophosphate, Parkinson's, Uncategorized | No Comments »
05
Jul
(Beyond Pesticides, July 5, 2023) After nearly 40 years since the Bhopal, India manufacturing facility leaked 47 tons of a chemical used in pesticide production, exposing half a million people and killing thousands, a new study in the BMJ Medical Journal has shed light on the enduring health and human capital effects resulting from in-utero exposure. The study finds significant negative impacts on both economic and health outcomes. Individuals who were in the womb during the disaster exhibited lower birth weights and remain more susceptible to respiratory problems, cognitive impairments, and other health issues later in life. Moreover, those born just after the gas leak were found to have lower educational attainment and reduced earning potential as adults. Over the past four decades, Beyond Pesticides has consistently reported on the Bhopal Gas Disaster, which stands as one of the most devastating industrial tragedies in history [1] [2] [3] [4]. The calamitous night of December 2, 1984, resulted from a gas leak of the highly toxic methyl isocyanate (MIC) from a Union Carbide Corporation (now owned by Dow Chemical Company) manufacturing facility. MIC is an intermediate chemical used in the production of insecticides such as carbaryl (Sevin), aldicarb, and other carbamate […]
Posted in Aldicarb, Carbamates, Carbaryl, Chemicals, Pesticide Regulation, Uncategorized | No Comments »
02
Mar
(Beyond Pesticides, March 2, 2023) Populations experiencing higher levels of environmental pollutant exposure, specifically pesticides, also experience a higher rate of irritable bowel syndrome (IBS), according to a study published in Environmental Toxicology and Pharmacology. IBS is a gastrointestinal disorder that causes abdominal pain or discomfort and changes in bowel behaviors. IBS affects 25 to 45 million individuals in the U.S., mostly female (two-thirds). Additionally, a quarter to half of all gastrointestinal-related visits are for IBS symptoms. Despite the unknown etiology of IBS, ample evidence demonstrates environmental contaminants, like pesticides, negatively affect the gut microbiota, causing a microorganism imbalance and resulting in inflammation associated with IBS. The gut, also known as the “second brain,” shares similar structural and chemical parallels to the brain. The microbiota in the gut plays a crucial role in lifelong digestion, immune and central nervous system regulation, as well as other bodily functions. Although studies show how chemical exposures affect overall human health, a growing body of peer-reviewed scientific literature is now questioning how these toxic chemicals influence gut health and the subsequent occurrence of diseases. The study notes, “These findings may help to understand the relationship between pesticide exposure and IBS; however, more epidemiological and experimental research is needed to understand […]
Posted in Carbamates, Chlorpyrifos, Inflammatory bowel disease (IBD), Microbiata, Microbiome, neonicotinoids, organophosphate, pyrethroids | No Comments »
22
Jan
(Beyond Pesticides, January 22, 2021) After the past four devastating years, hopes and expectations of the Biden/Harris administration abound among the environmental and public health communities. The ears and eyes of many advocates, as well as those in the agricultural community, are attuned (among myriad candidates) to the fate of the pesticide aldicarb. Although Environmental Protection Agency (EPA) registration of this terribly toxic insecticide was cancelled in 2010, various limited-use reapprovals since then have meant that the compound has found its way to increasing levels of use. On January 12, as another parting shot of midnight rulemaking, Trump’s EPA approved expanded uses (see below). The $64,000 question is whether the new administration will use its authority under the Congressional Review Act — which enables Congress to pass a joint resolution (then signed by the President) to overturn a new federal agency rule and prevent its reissuance in the future — to get this pesticide retired for good. Beyond Pesticides urges President Biden’s EPA to do so. Notably, the Trump administration used the Congressional Review Act to destroy myriad environmental rules when it came into power. This permitting of expanded aldicarb uses fits the pattern. Environmental Health News notes that, as of early […]
Posted in Agriculture, Aldicarb, Antibiotic Resistance, Bayer, Carbamates, Endocrine Disruption, Environmental Protection Agency (EPA), Uncategorized | No Comments »
04
Sep
(Beyond Pesticides, September 4, 2020) When pesticide drift is investigated, it is most often drift from agricultural fields that is examined. A new study shows that off-target drift of pesticides from greenhouses is also a reality. This research deduced such drift of organophosphate and carbamate pesticides from crop applications done in Ecuadoran floriculture greenhouses by evaluating the acetylcholinesterase enzyme (AChE) activity, necessary to the transmission of nerve impulses, in children residing nearby. The team finds that children living in homes near greenhouses in which these insecticides (widely recognized as cholinesterase inhibitors) are used exhibit reduced activity of this enzyme and abnormal functioning of the nervous system. Beyond Pesticides has monitored the pesticide drift issue intensively, and has long advocated for far better protections for farmworkers. This new information connects those issues, and expands the “drift” concerns to include risks to people working in greenhouses, and to those, especially children, who happen to live near greenhouse-type structures in which these toxic chemicals are used. The study evaluates data during three separate periods (2008, April 2016, and July–October 2016) on 623 children, aged 4–17, living in floricultural communities in Ecuador. The research is part of the study of the Secondary Exposure to Pesticides […]
Posted in Agriculture, Carbamates, Greenhouse, Nervous System Effects, organophosphate, Pesticide Drift, Uncategorized | No Comments »
