20
Aug
Modes of Action of Persistent Pesticides Documented, with Ongoing Poisoning and Multigenerational Effects
(Beyond Pesticides, August 20, 2024) A study published online in the journal Environmental Toxicology and Pharmacology raises continuing concern about residual exposure to organochlorine pesticides (OCPs) and the disruption that they and their metabolites and isomers cause to biological systems. For the most part, OCPs, including dichlorodiphenyltrichloroethane (DDT), are no longer used worldwide, but the legacy of their poisoning and contamination persists. A 2022 article in Environmental Science & Technology cites California condors and marine mammals along California’s coast contaminated with several dozen different halogenated organic compounds (hazardous, often-chlorinated chemicals) related to DDT, chlordane, and other now-banned legacy chemicals. Other research finds DDT in deep ocean sediment and biota. And, more research finds multigeneration effects from DDT exposure with grandmothers’ exposure to DDT increasing granddaughters’ breast cancer and cardiometabolic disorder risk. This study may be the first compilation of research regarding the modes of action for distinct types of organochlorine pesticides (OCPs). The findings raise the significant danger of legacy chemicals that persist for generations and call for a precautionary regulatory standard that is focused on preventing harm and advancing alternative nontoxic practices and products. In tracking the ongoing scientific literature on a broad spectrum of adverse effects daily, Beyond Pesticides […]