Archive for the 'mancozeb' Category
08
Apr
(Beyond Pesticides, April 8, 2025) A comprehensive literature review in Environment & Health analyzes evidence from human biomonitoring, epidemiological studies, and toxicological studies that link adverse effects on womenâs reproductive health, specifically impacting the ovary, to pesticide exposure. In examining the scientific literature, consisting of over 200 studies performed in the last 25 years, the authors find pesticide exposure threatens womenâs health through ovarian dysfunction. âEpidemiological studies have shown that pesticide exposures are associated with early/delayed menarche [first occurrence of menstruation], menstrual cycle disorders, early menopause, long time to pregnancy, polycystic ovary syndrome, primary ovarian insufficiency, infertility, and implantation failure in women,â the researchers state. They continue, âBoth in vivo [in animals] and in vitro [in cells] studies have shown that exposure to pesticides disrupts the estrous cycle, reduces the follicle pool, alters hormone levels, and impairs oocyte [egg] maturation.â These reproductive implications are noted with many different classes of pesticides, such as insecticides, including organochlorine pesticides (OCPs), organophosphates (OPs), pyrethroids, and neonicotinoids, as well as herbicides and fungicides. The authors, however, comment on present research gaps: âMuch of the available epidemiological evidence focuses on legacy insecticides, such as OCPs, and a subset of insecticides that are still in use […]
Posted in acetamiprid, Atrazine, Bifenthrin, Chlorpyrifos, cypermethrin, DDT, Deltamethrin, Diazinon, fenvalerate, Glyphosate, Imidacloprid, Infertility, lambda-cyhalothrin, Lindane, Malathion, mancozeb, Oxidative Stress, Permethrin, Reproductive Health, Thiamethoxam, vinclozolin, Women's Health | No Comments »
02
Apr
(Beyond Pesticides, April 2, 2025) In examining prenatal residential proximity of documented pesticide spraying in California to the menstrual cycle characteristics of 273 Latina adolescents, researchers report in the American Journal of Epidemiology a positive association between exposure to the insecticide methomyl and heavy bleeding. Other pesticides appear to influence menstrual symptoms as well. âAdolescentsâ menstrual cycle characteristics can be âvital signsâ of health and impact quality of life,â the authors share. They continue, âTo our knowledge, this is the first study to examine the association between prenatal pesticide exposure and menstrual outcomes in adolescents of any demographic group.â Menstrual cycle characteristics, such as dysmenorrhea (painful or uncomfortable menstrual cramps), irregularity, and heavy menstrual bleeding, can also be indicators of underlying health conditions, including endometriosis, polycystic ovary syndrome (PCOS), thyroid dysfunction, and bleeding disorders. By associating the pesticide exposure of mothers during pregnancy to impacts on their children, the researchers highlight important health risks for women and young girls that are often disregarded. âThe prenatal period is a critical period of reproductive development that may be particularly sensitive to endocrine disruption,â the researchers share. As previously reported by Beyond Pesticides, endocrine-disrupting chemicals are any synthetic or natural compounds that hinder […]
Posted in Acephate, California, Children, Chlorpyrifos, Diazinon, Dimethoate, Endocrine Disruption, endometriosis, Environmental Protection Agency (EPA), Glyphosate, Imidacloprid, Malathion, mancozeb, Maneb, Methomyl, Oxidative Stress, Permethrin, Reproductive Health, Women's Health | No Comments »
17
Dec
(Beyond Pesticides, December 17, 2024) A systematic review of studies on pesticides as endocrine-disrupting chemicals (EDCs) on body weight, published in Biomedicines, evaluates 36 clinical and preclinical studies and links their agricultural use to obesity. The authors, with the lead researchers from the School of Medicine and Health Sciences at Catholic University of Valencia San Vincente, Valencia, Spain, assess studies on a range of pesticides, including organophosphates, pyrethroids, neonicotinoids, and others. In addition to concluding that the EDCs promote obesity, they report that the chemicals cause âother anthropometric changes by altering lipid and glucose metabolism, modifying genes, or altering hormone levels such as leptin.â Endocrine disruption and obesity are public health concerns, and there is a wide body of science linking pesticide exposure to these effects (see more here). âObesity is considered to be a worldwide pandemic that leads to an increase in medical costs and thus becomes a public health problem,â the researchers share. They continue, â[Obesity] is also associated with the increased production of environmental chemicals, also called environmental obesogens, used mainly in agriculture, as disease vector control, helping to prevent harmful effects caused by fungi, bacteria, or even pests, using pesticides, insecticides, and herbicides, or endocrine disruptors […]
Posted in 2,4-D, acetamiprid, Benomyl, Bifenthrin, Carbamates, Carbendazim, Chlorpyrifos, Clothianidin, cypermethrin, Dicamba, Diuron, Endocrine Disruption, Fenoxycarb, Fipronil, Fungicides, Glyphosate, Imidacloprid, Isoxafutole, Malathion, mancozeb, Maneb, neonicotinoids, Obesity, organophosphate, Permethrin, Synthetic Pyrethroid, Thiamethoxam | No Comments »
12
Dec
(Beyond Pesticides, December 12, 2024) A literature review of 161 articles in Discover Toxicology finds that pesticides with different mechanisms of action cause memory and learning impairments. These effects are noted in nontarget species including humans. Pesticide â[e]xposure during development, as well as chronic environmental and occupational exposure, can contribute to decreased cognitive performance,â the researchers say. With a focus on organophosphate pesticides, synthetic pyrethroids, and neonicotinoid insecticides, the authors highlight neurological impacts. Both learning and memory are crucial for the survival of many species. “Considering the importance of learning and memory for human and non-human animal behavior and the growing association between pesticide exposure and cognitive impairment, the aim of this review was to describe the studies showing the impact of pesticide exposure on memory and learning abilities in nontarget species, providing evidence of the impact of pesticides in central nervous system function,â the researchers state. The 161 articles included in the review were identified through database searches in PubMed/Medline and Scielo. The authors note, âInclusion criteria for article selection included all articles published in English between 2015 and 2024 containing original studies in animals or humans with single or multiple pesticides exposure.â The articles consist of 132 preclinical […]
Posted in behavioral and cognitive effects, Bifenthrin, Brain Effects, Carbamates, Children, Chlorpyrifos, Clothianidin, Cyfluthrin, cypermethrin, Deltamethrin, Diazinon, Farmworkers, Flumethrin, Glyphosate, Imidacloprid, Learning Disabilities, Malathion, mancozeb, neonicotinoids, organophosphate, Oxidative Stress, Permethrin, Pollinators, pyrethroids, Synthetic Pyrethroid, thiacloprid, Thiamethoxam | No Comments »
08
Oct
(Beyond Pesticides, October 8, 2024) A comprehensive literature review in Endocrines, published in September, amasses hundreds of studies on endocrine-disrupting chemicals (EDCs) that showcase adverse effects on growth, development, reproduction, and metabolism. The authors, a team of scientists and academics from Brazil, shed light on the link between EDC use and thyroid dysfunction, leading to increasingly prevalent illnesses and deadly diseases. Â Â Â EDCs are any synthetic or natural compounds that hinder endocrine system functions and create harmful effects on organisms. These chemicals can impact the thyroid gland, which is vital in producing hormones and plays a role in several body functions. As the researchers state, âSeveral EDCs have been classified as thyroid disruptors, impairing thyroid hormone [TH] production, synthesis, metabolism, transport, and/or actions. Notably, thyroid disorders are the second most prevalent endocrine disease worldwide, with incidence increasing significantly in recent years.â The authors continue, â[S]tudies have correlated this rise in thyroid dysfunctions and cancers with increased exposure to EDCs. Although many EDCs are linked to thyroid dysfunction, this review focuses on the deleterious effects of plasticizers, organochlorine pesticides, and per- and poly-fluoroalkyl substances on thyroid function. These contaminants are commonly found in food, water, and everyday products.â This review helps […]
Posted in Atrazine, Birth defects, Cancer, carbamate, Carbamates, Children, Chlorpyrifos, DDT, Dieldrin, Endocrine Disruption, Endosulfan, Fipronil, mancozeb, organochlorines, organophosphate, Permethrin, PFAS, phthalates, Propiconazole, pyrethroids, Synthetic Pyrethroid, Thyroid Disease, Women's Health | No Comments »
02
Jul
(Beyond Pesticides, July 2, 2024) Men’s Mental Health Awareness Month, which took place last month, evokes concern about the growing body of science linking pesticide exposure to neurological effects linked to depression. Recent studies reveal elevated rates of psychiatric disorders, including suicide, among farmers, with problems more common for males. Through systematic reviews, meta-analyses, surveys and interviews, and blood sampling, these three studies add to the growing body of science linking pesticide exposure to neurological impacts. First, in the Journal of Agromedicine, researchers from Greece and the United Kingdom review eight studies and find a significant positive association between pesticide poisoning and depression in agricultural populations.1 Second, a study in Toxicology shows a link between depression in Brazilian farmers and pesticide exposure, most notably with glyphosate usage.2 Third, the latest study in Environmental Toxicology and Pharmacology focuses on work by researchers from Spain in identifying farmers exposed to chlorpyrifos, mancozeb, and malathion that have higher rates of depressive symptoms and suicide attempts.3 Through a meta-analysis of published research, the authors of the Agromedicine journal article identify pesticide poisoning as a risk factor of depression. With depression affecting more than 264 million individuals worldwide, this is a field of interest with […]
Posted in Atrazine, behavioral and cognitive effects, Chlorpyrifos, Depression, Farmworkers, Glyphosate, Malathion, mancozeb, men's health, Oxidative Stress, Paraquat, Permethrin, simazine, Suicide | No Comments »
03
Mar
(Beyond Pesticides, March 3, 2022) Childrenâs exposure to synthetic pyrethroid insecticides, particularly during the course of mosquito control operations, is associated with increased occurrence of certain respiratory diseases and allergic outcomes, finds research published in the journal Thorax late last month. With a pandemic respiratory virus continuing to spread throughout the world, it has become increasingly important to avoid environmental exposures that can harm lung health. This research underscores the critical need for homeowners, farmers, and vector control officials to shift away from chemical use as the first line of defense against pest problems in order to safeguard childrenâs health. A total of 303 women and their children participated in the study, which tracked pesticide exposure during pregnancy and then at age five. All participants in the study lived within roughly three miles of a banana plantation. A structured questionnaire captured a range of variables, from socioeconomic status to medical history, local environmental conditions, occupation, and demographics. Researchers collected urine samples from pregnant mothers during the first visit, and their children during the 5-year follow-up. Urine samples were analyzed for metabolites concerning a range of pesticides, including chlorpyrifos, synthetic pyrethroids, the fungicides mancozeb, pyrimethanil, and thiabendazole, and the herbicide 2,4-D. […]
Posted in 2,4-D, Chlorpyrifos, mancozeb, Mosquitoes, pyrimethanil, Synthetic Pyrethroid, thiabendazole, Uncategorized | No Comments »
