Archive for the 'organophosphate' Category
06
Jul
(Beyond Pesticides, July 6, 2023) A study published in Environmental Health Perspectives finds concentrations of organophosphate (OP) metabolites in urine during the prenatal phase have links to adolescent/young adult externalizing (e.g., hyperactivity, aggression, attention problems) and internalizing (e.g., depression) behavior problems. Thus, prenatal exposure to OP pesticides can permanently affect behavioral health as children mature into adulthood. This study adds to the growing body of research reinforcing the adverse effects of organophosphate (OP) exposure on cognitive health and neurological development, especially for infants and children. Prenatal development is one of the most vulnerable periods of exposure, as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. Given research links to pesticide exposure and neurological and cognitive development, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. Researchers gathered two urine samples from mothers during pregnancy (at weeks 13 and 26) and five urine samples from offspring from the ages of six months to five years old to measure urinary dialkylphosphates (DAPs) (nonspecific OP metabolites). Subsequently, the study also assesses reports of […]
Posted in behavioral and cognitive effects, Birth defects, Children, Depression, organophosphate | No Comments »
02
Jun
(Beyond Pesticides, June 2, 2023) Scientists have identified 97 different types of pesticides and flame retardants in primate fecal samples, recently reporting their results in the journal Biology Letters. In Uganda’s Kibale National Park, researchers studied the chemical exposure of four species of primates (chimpanzees, Ugandan red colobus, olive baboons and red-tailed monkeys), adding to previous research on the subject. The chemicals demonstrate a measurable effect on primate growth and development, sparking considerable unease as to the future health of these critical species. This study shows how even within a protected national park, wildlife species are at risk from chemical pollution. According to advocates, the use of dangerous pesticides and flame retardants, therefore, must be entirely stopped in order to protect the future viability of wildlife species. Scientists collected a total of 71 fecal samples from the four chosen species to measure levels of chemicals and hormones in a noninvasive manner. After sample analysis, researchers highlight three main groups of chemical pollutants: organochlorine pesticides (OCPs), brominated flame retardants (BFRs), and organophosphate esters (OPEs). Although in a protected area, wildlife species encounter humans through tourism, research, and human development surrounding the park. As these pesticides are so prevalent in areas of […]
Posted in Biodiversity, Biomonitoring, Endocrine Disruption, International, multi-generational effects, organochlorines, organophosphate, Pesticide Drift, Pesticide Residues, Wildlife/Endangered Sp. | No Comments »
28
Apr
(Beyond Pesticides, April 28, 2023) A study published in Science of The Total Environment finds agricultural communities encounter chronic and measurable pesticide exposure regardless of seasonal pesticide applications. Several biomonitoring studies demonstrate people living adjacent to or within agricultural areas often experience elevated levels of organophosphate (OP) insecticides, even while not working directly with OPs. Six dialkyl phosphate (DAP) metabolites (breakdown products) of OPs persist in urine during the spraying and non-spraying seasons. Despite 75 percent of OPs metabolizing into one or more of the six DAPs and excreting within six to 24 hours after exposure, the consistent levels of DAPs in urine highlight continuous exposure beyond regular seasonal pesticide applications. OP compounds have a global distribution, with evaporation and precipitation facilitating long-range atmospheric transport, deposition, and bioaccumulation of hazardous chemicals in the environment. OPs are highly toxic and, as this study shows, residues are consistently present in human and animal urine, as well as blood, tissues, and milk. Considering 90 percent of Americans have at least one pesticide compound in their body, primarily stemming from dietary exposure, including food and drinking water, advocates maintain that current restrictions on their use must adequately detect and assess total chemical contaminants. The study notes, “We suggest that among agricultural communities that experience […]
Posted in Agriculture, Body Burden, organophosphate | No Comments »
14
Mar
(Beyond Pesticides, March 14, 2023) A study published in Environmental Research and Public Health finds occupational pesticide exposure increases the risk of sleep disorders among farmworkers and pesticide applicators. Specifically, many pesticides, like organophosphates (OPs), are detrimental to neurological function through inhibition of the enzyme acetylcholinesterase (AChE) responsible for ending a neurotransmission event after relaying the necessary information. Without an end to neurotransmission events, individuals experience a buildup of acetylcholine, resulting in convulsions, headaches, weakness, impacts on bodily senses, and other cognitive/mental changes. In addition to illnesses from chemical exposure, inadequate sleep has links to several chronic diseases like type 2 diabetes, cardiovascular disease, obesity, and depression. Therefore, given research links to sleep-related disorders and bodily functions, including endocrine, metabolic, neurological, and cognitive disorders, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The study notes, “The study’s findings can be used to create strategies for addressing mental health issues and promoting mental health and quality of life.” Researchers assess the sleep patterns among individuals living in southeast Spain, near the coast of Almeria, where chemical-intensive agriculture from greenhouses is prevalent. Of the 380 participants in the study, 189 were […]
Posted in Brain Effects, Farmworkers, Nervous System Effects, organophosphate | No Comments »
09
Mar
(Beyond Pesticides, March 9, 2023) A study published in Environmental Research finds exposure to organophosphate (OP) compounds during pregnancy, or prenatal OP exposure can cause shortfalls in language development abilities at 18 months, stifling preschool-age language expression. Additionally, a timely and co-occurring study published in Environmental International confirms similar results, highlighting that chlorpyrifos (an organophosphate) impedes neurological and psychological development, including language communication and all motor skills of offspring at 12 and 18 months old. Prenatal development is one of the most vulnerable periods of exposure, as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. Given research links to pesticide exposure and neurological and cognitive development, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The Environmental Research authors note, “The etiology [cause] of language development is complex, and this work further highlights the importance of the prenatal environment as a mechanism of influence that are associated with deficits in early language acquisition and ability, which could signal increased behavioral problems and academic difficulties in later childhood that extend […]
Posted in behavioral and cognitive effects, Brain Effects, Children, multi-generational effects, Nervous System Effects, organophosphate, Women's Health | No Comments »
02
Mar
(Beyond Pesticides, March 2, 2023) Populations experiencing higher levels of environmental pollutant exposure, specifically pesticides, also experience a higher rate of irritable bowel syndrome (IBS), according to a study published in Environmental Toxicology and Pharmacology. IBS is a gastrointestinal disorder that causes abdominal pain or discomfort and changes in bowel behaviors. IBS affects 25 to 45 million individuals in the U.S., mostly female (two-thirds). Additionally, a quarter to half of all gastrointestinal-related visits are for IBS symptoms. Despite the unknown etiology of IBS, ample evidence demonstrates environmental contaminants, like pesticides, negatively affect the gut microbiota, causing a microorganism imbalance and resulting in inflammation associated with IBS. The gut, also known as the “second brain,” shares similar structural and chemical parallels to the brain. The microbiota in the gut plays a crucial role in lifelong digestion, immune and central nervous system regulation, as well as other bodily functions. Although studies show how chemical exposures affect overall human health, a growing body of peer-reviewed scientific literature is now questioning how these toxic chemicals influence gut health and the subsequent occurrence of diseases. The study notes, “These findings may help to understand the relationship between pesticide exposure and IBS; however, more epidemiological and experimental research is needed to understand […]
Posted in Carbamates, Chlorpyrifos, Inflammatory bowel disease (IBD), Microbiata, Microbiome, neonicotinoids, organophosphate, pyrethroids | No Comments »
22
Feb
(Beyond Pesticides, February 22, 2023) Combining neonicotinoid insecticides with other commonly used pesticides can result in synergistic effects on honey bees, increasing toxicity more than any individual chemical could, according to research published in Scientific Reports earlier this month. The data highlight the grave inadequacy of the U.S. Environmental Protection Agency’s (EPA) process for evaluating pesticide risks. Under current regulations, EPA requires chemical manufacturers to submit data only on singular active ingredients. Yet, pesticide products may be packaged or â€tank mixed’ with other, equally toxic pesticides without any obligation to determine the toxicity of the material that is actually being applied. Independent research is left to fill in these gaps, and the data increasingly shows that toxicity with pesticide mixtures amounts to a roll of the dice: sometimes combinations are less toxic, sometimes their toxicities are merely additive. But more often than not, pesticide mixtures result in synergistic effects that make the product significantly more toxic than either individual chemical alone. To understand how pesticide combinations are harming pollinators, scientists began with baseline data on the individual toxicity range that common pesticides pose to honey bee colonies. Research was conducted on honey bees reared in the Stoneville Wildlife Management Area […]
Posted in cypermethrin, Dimethoate, Environmental Protection Agency (EPA), esfenvalerate, Methomyl, neonicotinoids, organophosphate, Permethrin, Pollinators, tetraconazole, Thiamethoxam, Uncategorized | 1 Comment »
20
Dec
(Beyond Pesticide, December 20, 2022) A meta-analysis published in Chemosphere finds prenatal pesticide exposure, or pesticide exposure during pregnancy has a positive association with autism spectrum disorder (ASD) and attention deficit/hyperactive disorder (ADHD). Particularly, exposure to chemical classes organophosphate (OP) and pyrethroid (PYR) insecticides, in addition to the mother’s age during pregnancy (≥30 years old), increased the risk factor of ASD. ADHD risk increases among offspring whose mothers encounter organochlorine pesticides (OCPs) during gestation. The etiology or cause of ASD and ADHD involves the interaction of multiple components, including lifestyle and genetics. However, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, solvents, dietary residues, etc.) play a role in disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues resulting in chronic health effects. ADHD is estimated to affect 8-12% of school-age children worldwide. While it is a complex disease, and genetics may play a role, no specific genes have been identified, and there is increasing evidence that environmental factors like pesticide exposure facilitate the development of the condition. Additionally, U.S. Centers for Disease Control and Prevention (CDC) estimates that 1 in 54 children have been diagnosed with an autism spectrum […]
Posted in ADHD, Autism, behavioral and cognitive effects, Children, organochlorines, organophosphate, pyrethroids, Women's Health | No Comments »
17
Nov
(Beyond Pesticides, November 17, 2022) A report published in Toxicology and Applied Pharmacology finds organophosphate (OP) insecticides and the coronavirus (SARS-CoV-2/Covid-19) illicit similar damage to the heart and co-occurring exposure to both can escalate cardiac (heart) injury. Previous research suggests OPs may increase the ability of SARS-CoV-2 to cause COVID-19, especially among vulnerable individuals with underlying medical conditions. OPs have a wide range of biological uses—from insecticides to flame retardants—that make these chemicals ubiquitous, significantly contributing to ecosystem contamination. These compounds have a global distribution, with evaporation and precipitation facilitating long-range atmospheric transport, deposition, and bioaccumulation of hazardous chemicals in the environment. OPs are highly toxic, originating from the same compounds as World War II nerve agents, and residues are consistently present in human and animal blood, urine, tissues, and milk. Moreover, OPs are one of the leading causes of poisoning globally. Therefore, it is vital to understand how OP exposure will impact human health in conjunction with other immunologically compromising diseases like COVID-19. Cardiovascular diseases are among the leading causes of death globally. Additionally, heart conditions are one leading cause of disability in the U.S., as research demonstrates environmental pollutant exposure can increase the risk of developing cardiovascular disease, including stroke, heart attack, heart failure, atrial fibrillation, and cardiac […]
Posted in Cardiovascular Disease, Chlorpyrifos, coronavirus, COVID-19, Malathion, organophosphate, synergistic effects | No Comments »
19
Oct
(Beyond Pesticides, October 19, 2022) Pet flea collars containing the insecticide tetrachlorvinphos (TCVP) are set to be banned by the U.S. Environmental Protection Agency, according to the agency’s long overdue response to a petition from the Natural Resources Defense Council (NRDC). The highly toxic pesticide has not been used on crops since 1987, yet was permitted for decades in flea collars where children could be intimately exposed to the chemical while petting and playing with the family pet. The decade-long process of bringing use of these products to an end exposes the failures of the U.S. pesticide regulatory system, and how EPA’s weak and flawed decisions that infect the marketplace with severe consequences. One may ask: How many veterinarians prescribed these dangerous flea collars to pet owners, assuming that EPA has properly assessed exposure risks to their human owners? Advocates concerned about EPA’s ongoing propensity to defer to the pesticide industry are urging an overhaul of the regulatory process and a reorientation toward toxic pesticide elimination and the adoption of organic in order to address serious health and environmental threats. NRDC originally filed its petition to ban all uses of TCVP in 2009. The petition noted that the agency completely […]
Posted in behavioral and cognitive effects, Children, Nervous System Effects, organophosphate, Respiratory Problems, Uncategorized | No Comments »
03
Aug
(Beyond Pesticides, August 3, 2022) A systematic review of scientific studies on pesticides and fertility finds exposure associated with lower semen quality, DNA fragmentation, and chromosomal abnormalities. Published in the journal Andrology, the review is yet another warning from a long string of researchers sounding the alarm over the connection between global fertility and toxic chemical exposure. With data from the U.S. Centers for Disease Control and Prevention (CDC)Â indicating roughly 1 in 5 couples are unable to conceive after a year of trying, and trends continuing to slope downwards, it is critical that contributing factors be identified so that protective changes can be made. Â After screening over 1,300 studies, researchers narrowed their review down to 64 papers assessing semen parameters and DNA integrity after pesticide exposure. Each study is analyzed for its design, the pesticide investigated, Â the population studied, controls, and reproductive effects determined. Pesticides are evaluated for their impacts to sperm quality and DNA integrity based on their chemical class. Organochlorine insecticides, which are all banned but still persistent in soil, air, water, and food in the United States, include a range of impacts to sperm quality. Higher levels of DDT or its breakdown metabolite DDE are […]
Posted in Centers for Disease Control and Prevention, Infertility, organochlorines, organophosphate, Synthetic Pyrethroid, Uncategorized | No Comments »
28
Jul
(Beyond Pesticides, July 28, 2022) A report published in Chemosphere finds organophosphate (OP) insecticides readily contaminate drinking water resources, threatening human, animal, and ecological health. OPs have a wide range of biological uses—from insecticides to flame retardants—that make these chemicals ubiquitous, significantly contributing to ecosystem contamination. These compounds have a global distribution, with evaporation and precipitation facilitating long-range atmospheric transport, deposition, and bioaccumulation of hazardous chemicals in the environment. OPs are highly toxic, and residues are consistently present in human and animal blood, urine, tissues, and milk. Considering 90 percent of Americans have at least one pesticide compound in their body, primarily stemming from dietary exposure, including food and drinking water, advocates maintain that current restrictions on their use must adequately detect and assess total chemical contaminants. Water is the most abundant and crucial chemical compound on earth, essential to survival, and the main component of all living things. Less than three percent of that water is freshwater, and only a fraction of that freshwater is groundwater (30.1%) or surface water (0.3%) readily available for consumption. However, ubiquitous pesticide use threatens to reduce the amount of available freshwater as pesticide runoff, recharge, and improper disposal tends to contaminate adjacent waterways, like rivers, streams, lakes, or underground watersheds. With rivers and streams only accounting […]
Posted in Diazinon, Malathion, organophosphate, Water | 1 Comment »
24
May
(Beyond Pesticides, May 24, 2022) New research is providing strong causal evidence that Gulf War Illness (GWI) is the result of exposure to sarin gas, an organophosphate nerve agent used by Saddam Hussein as a chemical weapon during the Gulf War. The findings, published earlier this month in Environmental Health Perspectives, have important implications for the hundreds of thousands of American service members suffering from a constellation of chronic symptoms without a true understanding of how they became sick. “Quite simply, our findings prove that Gulf War illness was caused by sarin, which was released when we bombed Iraqi chemical weapons storage and production facilities,” said Robert Haley, MD, lead author of the study and epidemiologist at University of Texas Southwestern. “There are still more than 100,000 Gulf War veterans who are not getting help for this illness and our hope is that these findings will accelerate the search for better treatment.” Sarin was first synthesized in the late 1930s by Nazi chemists working for IG Farben (a consortium that included Bayer) in an attempt to create stronger and more powerful insecticides. Sarin is a G-series organophosphate (named after the scientists that created them), characterized by high acute toxicity and […]
Posted in Gulf War Syndrome, organophosphate, Uncategorized, Veterans Administraton | No Comments »
19
May
(Beyond Pesticides, May 19, 2022) A study published in the Journal of the American Heart Association finds a correlation between the number of fires fought annually and atrial fibrillation (AF), one of the most common medical arrhythmias that increases the risk of stroke, heart failure, and other cardiovascular health issues. In the firefighting occupation, firefighters can experience exposure to chemicals and particulate matter in smoke, pollutants, volatile organic compounds, and polycyclic aromatic hydrocarbons (PAHs) that increase cardiovascular (heart) and respiratory distress risk through oxidative stress and autonomic function disruption. However, firefighters encounter both personal and occupational (work-related) risk factors for cardiovascular diseases, making this subset of the population particularly vulnerable to heart-related fatalities. Considering firefighters live 10 to 15 years less than non-firefighters, studies like these are significant for understanding how chemical exposure contributes to health and wellness disparities. Lead author Paari Dominic, Ph.D., notes, “Clinicians who care for firefighters need to be aware of the increased cardiovascular risk, especially the increased risk of [AF], among this unique group of individuals… The conditions that elevate their risk further, such as high blood pressure, type 2 diabetes, lung disease and sleep apnea, should be treated aggressively. In addition, any symptoms of [AF], such as […]
Posted in Biomonitoring, Brain Effects, Cancer, Cardiovascular Disease, Environmental Justice, Occupational Health, organophosphate | No Comments »
12
May
(Beyond Pesticides, May 12, 2022) A report published in Environmental Health finds that exposure to environmentally relevant concentrations of pesticides can alter gut microbial communities, as demonstrated through fecal samples. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood and urine samples. Ample evidence demonstrates that environmental contaminants, including pesticides, negatively affect the human mouth and gut microbes. However, fecal samples provide an accurate representation of the microbial community existing in the gut. These toxicants can alter hormone metabolism, which adversely affects health outcomes. Adverse health effects of environmental contaminants include reproductive and developmental defects, diabetes, cardiovascular disease, liver disease, obesity, thyroid disorders, and improper immune operation. Although studies show how chemical exposures affect human health, more research is now questioning how these toxic chemicals influence gut health. Therefore, studies like these highlight the importance of evaluating how chemical contaminants deregulate normal bodily function through microbiome changes. The report notes, “Our results highlight the need for future dietary intervention studies to understand effects of pesticide exposure on the gut microbiome and possible health consequences.” Researchers examined dietary exposure to 186 common pesticide residues in the fecal excrement to determine impacts on the microbiome among 65 twins in the United Kingdom. […]
Posted in Alternatives/Organics, Glyphosate, Microbiata, Microbiome, organophosphate, pyrethroids, Synthetic Pyrethroids | 1 Comment »
16
Dec
(Beyond Pesticides, December 16, 2021) A study by Shanghai Jiao Tong University, China, finds Parkinson’s Disease (PD) risk increases with elevated levels of organochlorine (OCP) and organophosphate (OP) pesticides in blood. Among patients with PD, specific organochlorine compounds have greater associations with cognitive impairments, including depression and brain function. Research finds exposure to chemical toxicants, like pesticides, can cause neurotoxic effects or exacerbate preexisting chemical damage to the nervous system. Although the mechanism by which pesticides induce disease development remains unclear, researchers suggest changes in protein enzyme composition and cellular dysfunction from pesticide exposure interrupt normal brain function. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses each year. The disease affects 50% more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While only 10 to 15 percent of PD incidences are genetic, PD is quickly becoming the world’s fastest-growing brain disease. Therefore, research like this highlights the need to examine alternate […]
Posted in Brain Effects, organochlorines, organophosphate, Parkinson's | 1 Comment »
03
Jun
(Beyond Pesticides, June 3, 2021) A report published in Royal Society Open Science finds pesticide-resistant parasitic lice (Lepeophtheirus salmonis) are endangering wild and farmed fish populations in the North Atlantic. Extensive use of pesticides to rid the parasite has led to widespread resistance to multiple pesticides, prompting increasing infection rates among North Atlantic salmon populations. Overexploitation of wild fish and other ocean organisms has depleted seafood stocks globally. Some fisheries market aquaculture practices, like fish/seafood farming, as a solution to overfishing. However, the aquaculture industry repeatedly faces sustainability issues and fails to adhere to environmental regulations that threaten marine health. The oceans are essential to human health and well-being, feeding billions, supporting millions of jobs, and supplying medicinal materials. However, environmental contaminants like pesticides have profound impact on the ecosystem and the inhabitants. Therefore, it is necessary to understand how pesticides can influence resistance among lethal pest populations, especially in ecologically vulnerable and highly interconnected ecosystems like ocean basins. The authors of the report caution, “These results demonstrate the speed to which this parasite can develop widespread multi-resistance, illustrating why the aquaculture industry has repeatedly lost the arms race with this highly problematic parasite.” Over the past two decades, organophosphate and pyrethroid insecticides […]
Posted in Aquaculture, Aquatic Organisms, fish, organophosphate, pyrethroids, Resistance, Water | No Comments »
28
Apr
(Beyond Pesticides, April 28, 2021) New evidence set to be presented at the Experimental Biology (EB) 2021 meeting held this week suggests that Gulf War Veterans and other individuals with prior pesticide exposures may be more susceptible to Covid-19 infection. As the pandemic continues, it is critically important for researchers to better understand specific vulnerabilities in population groups in order to improve care and patient outcomes. “The reason why COVID-19 causes a severe form of disease leading to hospitalization and high rates of mortality in a small segment of society is unclear,” said Prakash Nagarkatti, PhD, co-author of the study and vice president for research at the University of South Carolina. “This work sheds new light on exposure to pesticides and potential susceptibility to COVID-19 through altered immune response.” Â According to recent data, out of 160,000 Covid-19 cases among veterans, the mortality rate was more than 4%. Researchers are pointing to Gulf War Syndrome, and past exposure to organophosphate pesticides as part of the problem. “We have identified a basic mechanism linked with inflammation that could increase susceptibility to COVID-19 infection among people exposed to organophosphates,” said Saurabh Chatterjee, PhD, from the University of South Carolina. Interleukin 6 (IL-6) […]
Posted in Chlorpyrifos, coronavirus, COVID-19, organophosphate, Uncategorized | No Comments »
18
Mar
(Beyond Pesticides, March 18, 2021) A new study published in Environmental Toxicology and Pharmacology finds chronic (long-term) organophosphate (OP) pesticide exposure increases adverse health and cancer risk for U.S. women relative to men. Organophosphorus pesticides have a wide range of biological uses—from insecticides to flame retardants—that make these chemicals ubiquitous, significantly contributing to ecosystem contamination. Furthermore, while organophosphates have less bioaccumulation potential, residues are consistently present in human and animal blood, urine, tissues, and milk. Although research demonstrates that OPs are highly toxic, there remains an inadequate understanding of how OP exposure impacts the nonagricultural population in the U.S., especially women. Therefore, it is essential to investigate the sex-specific health effects chemical contaminants can produce to mitigate exposure among vulnerable populations. Study researchers note, “Given the higher burden of OP exposure and their significantly higher overall health risk, including cancer, reducing OP exposure in U.S. women needs to be prioritized.” To examine the relationship between OP exposure and health risks, researchers investigated the presence of commonly detected OP metabolite concentrations in urine using participants from the U.S. National Health and Nutrition Examination Survey (NHANES). Urine samples measure OP metabolite as an indicator of OP exposure like previous agriculture-related population surveys. Study participants report health issues […]
Posted in Agriculture, Asthma, Breast Cancer, Cancer, Cardiovascular Disease, Endocrine Disruption, Environmental Justice, organophosphate, Women's Health | 1 Comment »
11
Feb
(Beyond Pesticides, February 11, 2021) California sea lions (Zalophus californianus) are experiencing high rates of urogenital carcinoma (UGC) cancer incidences from the combined effect of toxic “legacy” pesticides like DDT and the viral infection Otarine herpesvirus-1 (OtHV1), according to a new study published in Frontiers in Marine Science. Previous research documents the role herpesvirus infection, genotype, and organochlorine pesticides play in sea lion cancer development. However, synergism (collaboration) between viral infection and toxic chemical exposure increases cancer development odds. Pollution of the oceans with toxic chemicals lacks adequate regulation, is widespread and only getting worse. More than 80 percent of ocean pollution comes from land-based, anthropological activities. A recent study published in Annals of Public Health finds toxic chemicals from pesticides, heavy metals, plastics, and other sources readily contaminate the ocean, especially near coastal regions where chemical inputs occur in higher concentrations. Globally, pollution has major disease implications, causing the deaths of over nine million people annually. Therefore, it is essential to understand the co-effects of ocean pollution and diseases to protect human health. Authors of the study state, “This study has implications for human health, as virally associated cancer occurs in humans, and likelihood of cancer development could similarly be increased by exposure to environmental […]
Posted in Aquatic Organisms, Cancer, contamination, Herbicides, organochlorines, organophosphate, Water, Wildlife/Endangered Sp. | No Comments »
04
Feb
(Beyond Pesticides, February 4, 2021) A review published in Food and Chemical Toxicology suggests organophosphorus pesticides (OPs) may increase the ability of SARS-CoV-2 to cause COVID-19, especially among vulnerable individuals with underlying medical conditions. Organophosphorus pesticides have a wide range of biological uses that makes these chemicals ubiquitous, significantly contaminating both terrestrial (land) and aquatic (water) environments. However, OPs are highly toxic, originating from the same compounds as World War II nerve agents. Moreover, OPs are one of the leading causes of poisoning globally. Therefore, it is vital to understand how OPs exposure will impact human health in conjunction with other immunologically compromising diseases like COVID-19. Considering COVID-19 and OP exposure act similarly on the respiratory system, exacerbating adverse inflammatory responses, reviews like these highlight the significance of evaluating synergism between diseases and toxic chemicals to safeguard human health. Researchers in the study note, “To curb SARS-CoV-2 infection, a healthy immune system is obligatory despite potent vaccine to alleviate morbidities in patients. But unintentional exposure to OP compounds from several sources can rupture the antiviral defense against SARS-CoV-2. Moreover, respiratory ailments may also be fueled by OP compounds. Hence, SARS-CoV-2 mediated morbidities and fatalities could be backed by unintentional exposure to OPs in […]
Posted in coronavirus, COVID-19, organophosphate | No Comments »
24
Sep
(Beyond Pesticides, September 24, 2020) A new report by the U.S. Geological Survey (USGS), National Water-Quality Assessment (NAWQA) Project, reveals the presence of pesticides is widespread in U.S. rivers and streams, with over almost 90 percent of water samples containing at least five or more different pesticides. Pesticide contamination in waterways is historically commonplace as a 1998 USGS analysis revealed pesticides are commonly found in all U.S. waterways, with at least one pesticide detectable. Thousands of tons of pesticides enter rivers and streams around the U.S. from agricultural and nonagricultural sources, which contaminate essential drinking water sources, such as surface water and groundwater. As the number of pesticides in waterways increases, it has detrimental impacts on aquatic ecosystem health, especially as some pesticides work synergistically with others to increase the severity of the effect. Reports like these are a significant tool in determining appropriate regulatory action to protect human, animal, and environmental health. USGS concludes, “Identification of primary contributors to toxicity could aid efforts to improve the quality of rivers and streams to support aquatic life.” Water is the most abundant and important chemical compound on earth, essential to survival and the main component of all living things. Less than three percent of that water […]
Posted in Aquatic Organisms, contamination, Imidacloprid, organophosphate, Pesticide Mixtures, Water | No Comments »
04
Sep
(Beyond Pesticides, September 4, 2020) When pesticide drift is investigated, it is most often drift from agricultural fields that is examined. A new study shows that off-target drift of pesticides from greenhouses is also a reality. This research deduced such drift of organophosphate and carbamate pesticides from crop applications done in Ecuadoran floriculture greenhouses by evaluating the acetylcholinesterase enzyme (AChE) activity, necessary to the transmission of nerve impulses, in children residing nearby. The team finds that children living in homes near greenhouses in which these insecticides (widely recognized as cholinesterase inhibitors) are used exhibit reduced activity of this enzyme and abnormal functioning of the nervous system. Beyond Pesticides has monitored the pesticide drift issue intensively, and has long advocated for far better protections for farmworkers. This new information connects those issues, and expands the “drift” concerns to include risks to people working in greenhouses, and to those, especially children, who happen to live near greenhouse-type structures in which these toxic chemicals are used. The study evaluates data during three separate periods (2008, April 2016, and July–October 2016) on 623 children, aged 4–17, living in floricultural communities in Ecuador. The research is part of the study of the Secondary Exposure to Pesticides […]
Posted in Agriculture, Carbamates, Greenhouse, Nervous System Effects, organophosphate, Pesticide Drift, Uncategorized | No Comments »