Archive for the 'Chemicals' Category
07
Oct
(Beyond Pesticides, October 7, 2022) Pyrethroid insecticides are associated with the growing worldwide epidemic of non-alcoholic fatty liver disease (NAFLD), a condition that causes swelling of the liver and can eventually lead to cirrhosis, cancer, or liver failure. According to research published in Environmental Science and Ecotechnology, exposure to pyrethroids like bifenthrin can induce gut microbiota dysbiosis (an imbalance in microorganisms in the intestines). This dysbiosis results in abnormal lipid (fat) metabolism and subsequent accumulation of lipids in liver cells, contributing to NAFLD development. Gut microbiota plays a crucial role in lifelong digestion, immune and central nervous system regulation, as well as other bodily functions. Through the gut biome, pesticide exposure can enhance or exacerbate the adverse effects of additional environmental toxicants on the body. Since the gut microbiome shapes metabolism, it can mediate some toxic effects of environmental chemicals. However, with prolonged exposure to various environmental contaminants, critical chemical-induced changes may occur in the gut microbes, influencing adverse health outcomes. Considering NAFLD is becoming the most prevalent form of liver disease, impacting at least 25 percent of the globe, and a growing body of evidence demonstrates the significance gut microbiota play in overall health, safety analyses that currently do not consider the […]
Posted in Liver Damage, Liver failure, Pesticide Residues, Synthetic Pyrethroid, Synthetic Pyrethroids | No Comments »
06
Oct
(Beyond Pesticides, October 6, 2022) A new study finds alarmingly high levels of PFAS (Per- and Polyfluoroalkyl Substances) âforever chemicalsâ in commonly used pesticides, calling into question assurances from the U.S. Environmental Protection Agency (EPA) that contamination is limited to storage containers. For some pesticides, PFAS levels are nearly one billion times higher than the EPAâs recently updated Health Advisory for the PFAS chemical PFOS. âIf the intent was to spread PFAS contamination across the globe there would be few more effective methods than lacing pesticides with PFAS,â said Kyla Bennett, PhD, of the nonprofit Public Employees for Environmental Responsibility. âThese findings point to an appalling regulatory breakdown by EPA.â A team of researchers based in Texas, including scientists from Texas Tech and the U.S. Department of Agricultureâs (USDA) Cropping Systems Research Laboratory, participated in the study published in the Journal of Hazardous Materials Letters. Ten different formulated pesticide products were tested for 24 different PFAS substances. The pesticide products selected were determined based on unexpected PFAS contamination at USDAâs research facility. During the course of conducting a separate study on plant uptake of PFAS, detectable levels of PFAS were found in plants intended to be used as unexposed controls. […]
Posted in 3M, Agriculture, contamination, Environmental Protection Agency (EPA), Imidacloprid, Inerts, Malathion, neonicotinoids, PFAS, spiromesifen, Uncategorized, US Department of Agriculture (USDA) | 2 Comments »
05
Oct
(Beyond Pesticides, October 5, 2022) Exposure to widely used synthetic pyrethroids, present in many mosquito adulticides and household insecticides like RAID, is associated with a diagnosis of rheumatoid arthritis, according to research published in Environmental Science and Pollution Research. This is the latest pesticide-induced disease associated with this dangerous class of chemicals â a harm to individual Americans that the U.S. Environmental Protection Agency (EPA) is not considering when it registers pesticides. To remedy the major deficiencies in EPAâs reviews, and protect residents from chronic disease, more and more communities are transitioning to safer, organic pest management practices that do not require pyrethroids and other toxic synthetic pesticides. Rheumatoid arthritis (RA) is an autoimmune disease that causes systemic inflammation throughout the body, resulting in progressive damage to an individualâs joints. In the United States, roughly 1.3 million adults suffer from RA, accounting for nearly 1% of the adult population. Health care costs associated with the disease reach nearly $20 billion annually. To better understand the etiology behind the disease, an international team of researchers from China, Illinois, and Missouri analyzed data from the 2007-2014 National Health and Nutrition Examination Survey (NHANES), a long-running program that began in the early 1960s […]
Posted in ADHD, Children, Environmental Protection Agency (EPA), Mosquitoes, Nervous System Effects, Rheumatoid arthritis, Synthetic Pyrethroid, Uncategorized | 1 Comment »
04
Oct
(Beyond Pesticides, October 4, 2022) A study published in Environmental Pollution finds pyrethroid insecticides contribute to a secondary source of contamination in water resources. Various pyrethroids, including bifenthrin, are detectable in urban catch basins (storm drains) that collect runoff water before draining into the open environment. There is a lack of information regarding the pesticidesâ presence in urban catch basins. However, pesticide contamination in water resources is historically commonplace and widespread throughout U.S. rivers and streams, with at least five different pesticides present in 90 percent of water samples. Moreover, thousands of tons of pesticides not only enter waterways (e.g., rivers, streams, lakes, oceans) around the U.S. through urban catch basins but agricultural and nonagricultural sources as well, contaminating essential drinking water sources, such as surface water and groundwater. Reports like these are essential for determining appropriate regulatory action to protect the human, animal, and environmental health from chemical toxicant contamination, especially if chemical contamination is highly detectable. The study notes, âThe high detection frequency of bifenthrin and overall pyrethroid concentrations, especially for particle-bound residues, suggest that underground urban catch basins constitute an important secondary source for extended and widespread contamination of downstream surface waters by pesticides such as pyrethroids in urban […]
Posted in Aquatic Organisms, Bifenthrin, contamination, Pesticide Residues, Synthetic Pyrethroid, Synthetic Pyrethroids, Water, Wildlife/Endangered Sp. | No Comments »
30
Sep
(Beyond Pesticides, September 30, 2022) In late September, the U.S. Environmental Protection Agency (EPA) announced the withdrawal of its Interim Decision on glyphosate, the active ingredient in multiple herbicides, most notably Monsantoâs (now Bayerâs) Roundup. The action follows a slew of developments related to the herbicide, including: the 2015 International Agency for Research on Cancerâs declaration of its carcinogenicity; legal judgments and massive rewards to victims who developed cancers after chronic exposures; advocate efforts to get EPA to recognize the dangers of, and curtail, its use; and pushback from industry â most of the latter two coming in the form of litigation. The withdrawal of that Interim Decision means, on the ground that this harmful compound can continue to be used until a next regulatory review decision by EPA. Beyond Pesticides has long been engaged in education on and advocacy against glyphosate use, and was a plaintiff in the 2020 lawsuit, with the Center for Food Safety (CFS), et al., against EPA for this 2020 Interim Decision (ID). Under FIFRA (the Federal Insecticide, Fungicide and Rodenticide Act) each pesticide must be reviewed by EPA every 15 years âto ensure that existing pesticide products continue to perform their intended function without […]
Posted in Bayer, Cancer, Environmental Protection Agency (EPA), Glyphosate, Litigation, Monsanto, non-Hodgkin's Lymphoma, Pesticide Regulation, Uncategorized | No Comments »
29
Sep
(Beyond Pesticides, September 29, 2022) A study published in the International Journal of Hygiene and Environmental Health finds an association between retinoblastoma risk and prenatal exposure to pesticides. Retinoblastoma is a rare eye cancer, with over 200,000 cases in the U.S., most of which are children under the age of five. Despite occurring among offspring, this cancer is often not hereditary. Instead, a mutation in the RB1 gene during early development in the womb destabilizes and augments cell growth. Although the etiology or cause of childhood eye cancer involves the interaction of multiple components like lifestyle and genetics, emerging evidence indicates that environmental contaminants like pesticides (e.g., occupational exposures, air pollution, pesticides, solvents, diet, etc.) play a role in disease etiology. Pesticide contamination is widespread in all ecosystems, and chemical compounds can accumulate in human tissues resulting in chronic health effects. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Already, studies find low levels of pesticide exposure during pregnancy or childhood cause adverse health effects from metabolic disorders to mental and physical disabilities. While medical advancements in disease survival are more prominent nowadays, childhood cancer remains the leading cause of death from disease among children. […]
Posted in Acephate, Birth defects, Bromacil, Cancer, Children | No Comments »
27
Sep
(Beyond Pesticides, September 27, 2022) Exposure to widely used neonicotinoid insecticides harms amphibians at multiple life stages, adversely affecting their ability to survive in the wild, according to research published in the Journal of Zoology. As long-lived, systemic insecticides, neonicotinoids are consistently found in U.S. waterways,  often above federal safety limits, making these findings particularly dangerous for frogs and other amphibians throughout the country. As troubling data piles up on this class of dangerous insecticides, which are damaging pollinators, birds, deer, aquatic wildlife, and human health, it is left to the public to place pressure on federal regulators and members of Congress to act. To understand the impact of neonicotinoids on amphibian life stages, researchers conducted a range of  experiments. These were designed to investigate how exposure to the neonicotinoid imidacloprid affected larval survival, sexual development, locomotor skills, and avoidance behavior of the wood frog (Rana sylvatica). Larval survival was examined by exposing tadpoles to 10 parts per billion (ppb) of imidacloprid, a rate lower than the lethal concentration expected to kill half of other frogs species in acute toxicity tests. Four treatment protocols were established, adding the variable of natural pond drying to half of the tested frogs to […]
Posted in Endocrine Disruption, Environmental Protection Agency (EPA), Imidacloprid, neonicotinoids, Pesticide Regulation, Uncategorized, Wildlife/Endangered Sp. | 2 Comments »
21
Sep
(Beyond Pesticides, September 21, 2022) Strawberry plants pollinated by wild bees exposed to neonicotinoid insecticides produce smaller berries than those pollinated by unexposed bees, finds research published in the journal PLOS One. The findings are yet another piece of evidence pointing to the need for major reforms in the way pesticides are evaluated and pollinators are protected in the United States. As decades of evidence have piled up on the dangers posed by long-lived, systemic, neonicotinoid insecticides, the U.S. Environmental Protection Agency (EPA) has done little to address the damage to pollinator populations, while needed legislation, the Saving Americaâs Pollinators Act, has languished in Congress without a hearing or a vote, despite having over 75 cosponsors. This new study describes a novel consideration for how neonicotinoids may harm pollinators and impact the food supply. “Previous studies have shown that clothianidin affects wild bees negatively in terms of foraging speed, development and reproduction. Our results indicate that it can also impair the bees’ ability to pollinate strawberry flowers,” says study coauthor Lina Herbertsson, PhD. Scientists established 12 outdoor cages each with 10 strawberry plants and 11 canola plants. For half of the cages, the canola plants were grown with seeds coated […]
Posted in Clothianidin, Cyfluthrin, Environmental Protection Agency (EPA), neonicotinoids, Pollinators, Uncategorized | No Comments »
14
Sep
(Beyond Pesticides, September 14, 2022) The U.S. Environmental Protection Agency (EPA) is confirming that PFAS (per and polyfluorinated alykyl substances) forever chemicals leach into pesticides from their storage containers, and is taking steps to remove 12 âinertâ PFAS ingredients that are currently allowed to be added to pesticide products. The agencyâs move is a step toward some measure of health protections from chemicals that may have been widely sprayed throughout many American communities, and have been linked to cancer, liver damage, birth and developmental problems, reduced fertility, and asthma. However, many advocates indicate EPAâs actions on PFAS inerts do not go far enough, and the agencyâs findings regarding leaching storage containers are accompanied by no meaningful restrictions on their use. Following reports and preliminary testing conducted in 2020 showing that PFAS chemicals are present in a widely used mosquito adulticide, EPA began investigating the source of this contamination. Testing on the product Anvil 10+10, produced by the company Clarke, resulted in detection of nine different PFAS chemicals. Early indications indicate that the high-density polyethylene (HDPE) containers used to store pesticides contained PFAS substances on their walls, and that those chemicals are leaching into the liquid pesticides stored in contaminated barrels. These […]
Posted in Centers for Disease Control and Prevention, Environmental Protection Agency (EPA), Maine, PFAS, Uncategorized, Water | 1 Comment »
07
Sep
(Beyond Pesticides, September 7, 2022) Neonicotinoid (neonic) insecticides are causing widespread contamination within deer populations in Minnesota, with recent data showing significant increases over sampling that took place just two years earlier. The Minnesota Department of Natural Resources (MDNR) began sampling the spleens of deer in the state after research conducted in South Dakota found widespread contamination, but also links to harmful effects as a result of the exposure. The latest findings will result in further testing, yet the sum of research on the dangers of neonicotinoids â not only to deer, but pollinators, birds, aquatic wildlife, and even human health â demands, according to advocates, a precautionary approach and meaningful restrictions on these potent systemic pesticides. Officials at MDNR have no explanation for the increase in contamination over the last sample period. “We’re not exactly sure why we saw that increase,” said Department of Natural Resources Ungulate Research Scientist Eric Michel, PhD, to mprnews.org. “But regardless, the two years of data are showing us that neonics are being detected pretty much across the state. When we look for them we find them in deer spleens. So that’s kind of the big takeaway from what we’re seeing right now.” Results […]
Posted in Contamination, Minnesota, neonicotinoids, Uncategorized, Wildlife/Endangered Sp. | 1 Comment »
01
Sep
(Beyond Pesticides, September 1, 2022) Low level exposure to synthetic pyrethroid insecticides at 6-8 months of age is associated with language development delays in two-year old toddlers, according to research published in Neurotoxicology this month. This is the latest study to link this class of chemicals to developmental delays in young children. Despite a steady drum of concerning research, the U.S. Environmental Protection Agency (EPA) in 2019 removed a crucial âsafety factorâ intended to protect childrenâs health from synthetic pyrethroids, allowing higher levels of the insecticides to be sprayed on food, in homes, and playing fields around the country. Â To investigate the impact of synthetic pyrethroids on language development, scientists enrolled 327 expectant mothers in their third trimester. The mothers, all from rural areas of China, were selected if they had no history of significant pesticide exposure or family history of serious disease. Urine samples were taken from the women during pregnancy, and from infants 6-8 months after birth. Scientists analyzed samples for concentrations of three different synthetic pyrethroid breakdown products (metabolites), including 3-phenoxybenzoic acid (3PBA), 4-fluoro-3-phenoxybenzoic acid (4F3PBA), and cis-2,2dibromovinyl-2,2-dimethylcyclopropane-1-carboxylic acid (DBCA). While 3PBA is a metabolite of many synthetic pyrethroids, 4F3PBA a more specific metabolite of cypermethrin, […]
Posted in ADHD, Autism, Brain Effects, Children, cypermethrin, Deltamethrin, Environmental Protection Agency (EPA), Reproductive Health, Synthetic Pyrethroid, Uncategorized, Women's Health | No Comments »
31
Aug
(Beyond Pesticides, August 31, 2022) No rainwater on Earth is safe for consumption and use as per-, and poly-fluoroalkyl substances (PFAS) readily contaminate the hydrological ecosystem (properties, distribution, and circulation of water), according to a study published in Environmental Science and Technology. This finding is concerning as it adds to research demonstrating chemical pollutants (e.g., pesticides, pharmaceuticals, PFAS, heavy metals, radioactive material, etc.) exceed the âplanetary boundaryâ contamination and needs addressing. The Stockholm Resilience Centre, Stockholm University study, âPlanetary Boundaries: Exploring the Safe Operating Space for Humanity,â emphasizes that there are nine âplanetary boundariesâ related to climate change, biodiversity loss, the nitrogen cycle, the phosphorous cycle, stratospheric ozone depletion, ocean acidification, global freshwater use, changes/intensification of land use, atmospheric aerosol loading, and chemical pollution. When crossing these boundaries, the risk of generating large-scale abrupt or irreversible environmental changes increases. In fact, anthropogenic (human) activities are increasing global contamination levels past safe thresholds. Studies have already found that current human operations are quantifiable in almost all nine planetary boundaries and exceed the threshold for at least four out of the nine boundaries. Most recently, a 2022 report concludes that humanity exceeds planetary boundaries related to environmental pollutants and other ânovel entities,â including plastics and pesticides. […]
Posted in contamination, PFAS, Water | No Comments »
30
Aug
(Beyond Pesticides, August 30, 2022) Minuscule amounts of the weed killer Roundup and its active ingredient glyphosate can result in damage to the nervous system, finds research led by scientists at Florida Atlantic University, published in Scientific Reports. As hundreds of millions of pounds of glyphosate continue to be sprayed on hundreds of millions of acres of land throughout the United States each year, recent data indicate that four out of five U.S. children and adults contain detectable levels of glyphosate in their bodies. The pesticide industry and its paid supporters tell Americans that although contamination is widespread, the levels found in humans are not cause for concern. This latest research significantly undermines that specious argument, finding impacts on critical nervous system processes at levels 300 times less than the lowest suggested amount on the Roundup label. âIt is concerning how little we understand about the impact of glyphosate on the nervous system,â said Akshay S. Naraine, MSc., coauthor and a PhD student at Florida Atlantic University. âMore evidence is mounting for how prevalent exposure to glyphosate is, so this work hopefully pushes other researchers to expand on these findings and solidify where our concerns should be.â To investigate the […]
Posted in Environmental Protection Agency (EPA), Glyphosate, Nervous System Effects, Poisoning, Uncategorized | 10 Comments »
26
Aug
(Beyond Pesticides, August 26, 2022) New research from a team in California finds one-third of pesticides it reviewed â including glyphosate, paraquat dichloride, and oxyfluorfen â to be associated with the development of thyroid cancer. Researchers investigated the links between exposure to pesticides â including 29 that cause DNA cell damage â and the risk of this cancer. The researchers also find that in all the single-pollutant models they employed, paraquat dichloride â a widely used herbicide â was linked to this cancer. In 2021, Beyond Pesticides covered research by the U.S. National Institutes of Health (NIH) that demonstrated that exposures to lindane and metalaxyl also cause heightened risk of thyroid cancer. These study findings add to the already considerable concern about pervasive pesticide exposure â not only among farmers and applicators, but also in the general population. It is worth noting that, in addition to elevated thyroid cancer risks, multiple pesticides can cause other health damage. Paraquat is also acutely toxic, and can cause longer-term reproductive, renal, and hepatic damage to humans; it is toxic to birds, fish, and other aquatic organisms, and slightly so to honeybees. Glyphosate, as Beyond Pesticides has written frequently, is carcinogenic, and is associated […]
Posted in California, Cancer, Glyphosate, oxyfluorfen, Paraquat, Thyroid Disease, Uncategorized | No Comments »
25
Aug
(Beyond Pesticides, August 25, 2022) A study published in World Journal of Pediatrics finds an association between antibiotic and neonicotinoid (neonic) exposure and onset of pediatric (childhood) type 1 diabetes (T1D) through effects on the gut microbiome. Individuals with type 1 diabetes are at higher risk of other autoimmune disorders, including thyroid and celiac disease. Ample evidence demonstrates environmental contaminants like pesticides and antibiotics negatively affect human mouth and gut microbes. Through the gut biome, pesticide exposure can enhance or exacerbate the adverse effects of additional environmental toxicants on the body. Moreover, studies find low levels of pesticide exposure during pregnancy or childhood cause adverse health effects from metabolic/immune disorders to mental and physical disabilities. Children are particularly vulnerable to the impacts of pesticide exposure as their developing bodies cannot adequately combat exposure effects. Although studies show how chemical exposures affect overall human health, more research is now questioning how these toxic chemicals influence gut health and subsequent occurrence of diseases. In children, gut microbiome disruption, or gut dysbiosis, has significant associations with type 1 diabetes development, and disruption of gut microbiota plays a role in type 2 diabetes development. Over 11 percent (>37 million) of individuals in the U.S. have diabetes, and cases are growing by millions annually. With increasing rates of type 1 and […]
Posted in Acephate, Antibiotic Resistance, Children, Diabetes, Microbiome, neonicotinoids | 1 Comment »
24
Aug
(Beyond Pesticides, August 24, 2022) New research is helping the medical community understand the mechanism through which exposure to the banned insecticide DDT increases risk of Alzheimerâs disease. Published in the journal Environmental Health Perspectives, a team of researchers from Florida International University and Rutgers used multiple models to demonstrate the effects of DDT on the production of toxic proteins in the brain. The constant stream of new health risks regarding a chemical banned decades ago underlines the importance of a precautionary approach to pesticide regulation, particularly as red flags are already being raised about the connection between widely used weed killers like glyphosate and neurodegenerative diseases like Alzheimerâs. “The vast majority of research on the disease has been on genetics — and genetics are very important — but the genes that actually cause the disease are very rare,” says study coauthor Jason Richardson, PhD of Florida International University. “Environmental risk factors like exposure to DDT are modifiable. So, if we understand how DDT affects the brain, then perhaps we could target those mechanisms and help the people who have been highly exposed.” Previous research from Dr. Richardson found that DDT exposure increased risk of Alzheimer’s by four times. Scientists […]
Posted in Alzheimers's, DDT, Uncategorized | 1 Comment »
16
Aug
(Beyond Pesticides, August 16, 2022) Over half of all food samples tested by the U.S. Food and Drug Administration (FDA) contain the residues of at least one pesticide, and one in ten samples have levels that violate legal limits established by the U.S. Environmental Protection Agency (EPA). These findings, published by FDA this month in its 2020 Pesticide Residue Monitoring Report, are simply par for the course for government regulators, as FDA indicates the 2020 results âwere consistent with recent years.â However, while reporting on the dangerous pesticides present in U.S. food has become routine for FDA, more and more Americans are rejecting regular exposure to unnecessary toxics in their food by going organic with their food choices, planting their own pesticide-free gardens, and encouraging their elected officials to embrace safer, sustainable land care policies. Â FDA has conducted a review of pesticide residues on food on an annual basis since 1987, evaluating both domestic and imported foodstuffs into the US market. While EPA sets âpesticide tolerances,â also known as âmaximum residue levels,â of allowed pesticide residues on certain foods, FDA (and USDA, for some specific items like meat, poultry, and eggs) is tasked with enforcing these provisions. Pesticide tolerances, […]
Posted in Agriculture, Azoxystrobin, Environmental Protection Agency (EPA), Food and Drug Administration (FDA), Imidacloprid, Uncategorized | 1 Comment »
12
Aug
(Beyond Pesticides, August 12, 2022) Gestational (during pregnancy) exposure to endocrine disrupting chemicals (EDCs) like pesticides, per- and polyfluoroalkyl substances (PFAS), among others, may increase pediatric (child) liver injury and non-alcoholic fatty liver disease (NAFLD) risk, according to a study published in Environmental Health. Past studies associate exposure to EDCs with increased susceptibility to adverse health effects during critical fetal and childhood developmental periods. The World Health Organization (WHO), European Union (EU), and endocrine disruptor expert (deceased) Theo Colborn, Ph.D., classify over 55 to 177 chemical compounds as endocrine disruptors, including various household products like detergents, disinfectants, plastics, and pesticides. Endocrine disruption can lead to several health problems, including hormone-related cancer development (i.e., thyroid, breast, ovarian, prostate, testicular), reproductive dysfunction, and diabetes/obesity that can span generations. Because EDCs are ubiquitous because they are found in many products, studies report that these toxic chemical compounds are detectable in infants, children, and pregnant women. Furthermore, pregnant women can readily transfer compounds to the developing fetus through the placenta. Therefore, it is essential to understand the mechanism behind how harmful chemical exposure induces endocrine disruption during critical developmental periods. Researchers note, âConsidering the lack of studies on endocrine disruption and pediatric NAFLD, research like this highlights the need to understand the underlying […]
Posted in Endocrine Disruption, Liver Damage, Liver failure, PFAS, phthalates, Uncategorized | 1 Comment »
09
Aug
(Beyond Pesticides, August 9, 2022) The most widely used pesticide chemicals in the United States are not listed on product labels, yet pose widespread environmental and public health hazards, according to commentary published this month in Environmental Health Perspectives by two veteran researchers. At issue are adjuvants and so-called “inert” (or “other”) ingredients, chemicals that are added to formulated pesticide products, but do not undergo the same safety reviews as the active ingredient in pesticide products. This donut hole of regulation has permitted, as the commentary shows, millions of pounds of chemicals to be applied in California and throughout the country without proper scientific evaluation of their human health or ecological impact. Researchers first draw a distinction between adjuvant products and inert ingredients in pesticide products. Adjuvants are materials specifically designed to improve the performance of a pesticide spray and are sold separately from formulated pesticide products. Adjuvants are âtank mixedâ with a pesticide prior its application. Inert ingredients are any ingredient within a formulated pesticide product that is not designed to prevent, destroy, or repel a pest. Adjuvants and inert ingredients can be the same material â the difference lies in when they are added to a formulated pesticide […]
Posted in Endocrine Disruption, Environmental Protection Agency (EPA), Inerts, Uncategorized, Îą-(p-nonylphenyl)-Ď-hydroxypoly(oxyethylene) (APNOHO) | No Comments »
04
Aug
(Beyond Pesticides, August 4, 2022) An Arizona State University (ASU) study shows that the popular herbicide glyphosate can infiltrate the brain through the blood (blood-brain barrier), increasing neurological disease risk. The blood-brain barrier filters various molecules entering the brain from the circulatory system. However, the permeation of glyphosate molecules elevates the expression of TNFÎą and the accumulation of soluble beta-amyloid (Aβ) proteins in the brain and has associations with immune, inflammatory, and neurodegenerative diseases like Alzheimerâs disease (AD). More than 6 million people in the U.S. are living with Alzheimerâs, and cases are expected to double by 2050. Although Alzheimerâs research has focused heavily on finding genetic causes of the disease, fewer than half of cases are genetic. Thus, researchers are now evaluating how environmental contaminants may increase disease risk. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood and urine samples and can increase neurotoxicity risk when crossing the brain barrier. Therefore, studies like this highlight the importance of understanding how chemical accumulation in the body can impact long-term health and disease prognosis. The study notes, âBrain glyphosate correlates with increased TNFÎą levels, suggesting that exposure to this herbicide may trigger neuroinflammation in the brain, which may […]
Posted in Alzheimers's, Brain Effects, Glyphosate, Motor neuron disease, Nervous System Effects | No Comments »
03
Aug
(Beyond Pesticides, August 3, 2022) A systematic review of scientific studies on pesticides and fertility finds exposure associated with lower semen quality, DNA fragmentation, and chromosomal abnormalities. Published in the journal Andrology, the review is yet another warning from a long string of researchers sounding the alarm over the connection between global fertility and toxic chemical exposure. With data from the U.S. Centers for Disease Control and Prevention (CDC)Â indicating roughly 1 in 5 couples are unable to conceive after a year of trying, and trends continuing to slope downwards, it is critical that contributing factors be identified so that protective changes can be made. Â After screening over 1,300 studies, researchers narrowed their review down to 64 papers assessing semen parameters and DNA integrity after pesticide exposure. Each study is analyzed for its design, the pesticide investigated, Â the population studied, controls, and reproductive effects determined. Pesticides are evaluated for their impacts to sperm quality and DNA integrity based on their chemical class. Organochlorine insecticides, which are all banned but still persistent in soil, air, water, and food in the United States, include a range of impacts to sperm quality. Higher levels of DDT or its breakdown metabolite DDE are […]
Posted in Centers for Disease Control and Prevention, Infertility, organochlorines, organophosphate, Synthetic Pyrethroid, Uncategorized | No Comments »
02
Aug
(Beyond Pesticides, August 2, 2022) Members of the United States Senate are calling on the U.S. Fish and Wildlife Service (FWS) to phase out the use of toxic pesticides in National Wildlife Refuges in order to protect declining wildlife species and the countryâs unique natural resources. Led by Senator Cory Booker (D-NJ), the senators sent a letter to FWS Director Martha Williams urging FWS to âexpeditiously begin a rulemaking process to phase out the use of agricultural pesticides on National Wildlife Refuges.â The move comes at a time when native wildlife and the ecosystems humans rely upon are under greater threats than ever before from climate change, habitat destruction, and the indiscriminate use of toxic pesticides. âThe Refuge System was established to provide sanctuary for listed threatened and endangered species, migratory birds, and other wildlife,â wrote the senators in a letter to U.S. Fish & Wildlife Director Martha Williams. âThe Refugesâ migratory sanctuary and breeding grounds are especially critical for North American birds, as they have faced precipitous population declines; there are 3 billion fewer breeding birds in North America than there were in 1970. Unfortunately these birds and other threatened species are being put at risk by pesticide use […]
Posted in Alternatives/Organics, Biodiversity, Department of Interior, Fish and Wildlife Service (FWS), neonicotinoids, Uncategorized | 6 Comments »
28
Jul
(Beyond Pesticides, July 28, 2022) A report published in Chemosphere finds organophosphate (OP) insecticides readily contaminate drinking water resources, threatening human, animal, and ecological health. OPs have a wide range of biological usesâfrom insecticides to flame retardantsâthat make these chemicals ubiquitous, significantly contributing to ecosystem contamination. These compounds have a global distribution, with evaporation and precipitation facilitating long-range atmospheric transport, deposition, and bioaccumulation of hazardous chemicals in the environment. OPs are highly toxic, and residues are consistently present in human and animal blood, urine, tissues, and milk. Considering 90 percent of Americans have at least one pesticide compound in their body, primarily stemming from dietary exposure, including food and drinking water, advocates maintain that current restrictions on their use must adequately detect and assess total chemical contaminants. Water is the most abundant and crucial chemical compound on earth, essential to survival, and the main component of all living things. Less than three percent of that water is freshwater, and only a fraction of that freshwater is groundwater (30.1%) or surface water (0.3%) readily available for consumption. However, ubiquitous pesticide use threatens to reduce the amount of available freshwater as pesticide runoff, recharge, and improper disposal tends to contaminate adjacent waterways, like rivers, streams, lakes, or underground watersheds. With rivers and streams only accounting […]
Posted in Diazinon, Malathion, organophosphate, Water | 1 Comment »