(Beyond Pesticides, May 10, 2022) Widespread weed resistance on chemical corn and soybean farms is leading farmers to till their fields more often, significantly increasing greenhouse gas (GHG) emissions. These findings were published late last month in the journal Nature Food by a team of Iowa State University researchers. With agricultural practices accounting for roughly 10% of U.S. GHG emissions, and 25% of worldwide releases, farming practices that preserve soil health and sequester GHGs are essential for the future of food production. Tillage is a farming practice that can provide a range of benefits for crop production, but only in the right conditions. A range of tillage practices exist, ranging from yearly conventional tillage, where most crop residue is plowed into the soil, to conservation tillage where some residue remains, and no-till systems where the soil remains covered. Repeated tillage causes significant harm to soil structure and biology, and result in erosion and the release of GHGs like carbon dioxide, methane, and nitrous oxide from soil into the atmosphere. The harms of tillage have led both chemical and organic farmers toward no-till or reduced tillage systems. Organic no-till farming, as practiced by farming groups like the Rodale Institute, employs the […]

(Beyond Pesticides, May 9, 2022) While the U.S. Environmental Protection Agency (EPA) updated its guidelines for pollinator risk assessments in 2014, the agency continues to either fail to conduct full assessments, or dismiss concerning data it receives. EPA appears to discount threats like the insect apocalypse, evidenced by a 75% decline in insect abundance, which threatens not only global ecosystems, but also food production that depends on animal pollination. As pesticides move through the food web, birds are also at risk. Bird numbers are down 29% since Rachel Carson wrote Silent Spring in 1962. Tell EPA To Protect Against Other Threats to Pollinators. Tell Congress To Insist that EPA Does Its Job. The problem is highlighted by EPA’s recent Interim Decision on fenbuconazole, in which the agency notes that, “For larval bees, RQs (risk quotients) exceed the LOC (level of concern) for all pollinator attractive uses including when assessed at the lowest application rate of 0.0938 lb a.i./Acre (RQ = 1.1).” Yet in the same document, the agency declares that “…the benefits of fenbuconazole (e.g., efficacy in management of fungal pathogens) outweigh any remaining risk and that continuing to register fenbuconazole provides significant benefits, including its ability to increase crop […]

(Beyond Pesticides, May 6, 2022) A December 2021 report commissioned by the trade group Salmon Scotland concludes that the use of pesticide products by the nation’s salmon farms represents potential risk to “wild” swimmers (those who swim in open ocean waters). The report’s primary finding is that the use of insecticide products containing azamethiphos (an organophosphate), deltamethrin, and hydrogen peroxide to control sea lice in farmed fish contaminates sea water and, thus, threatens swimmers in the areas around the farms. Beyond Pesticides has reported on pesticide use in aquaculture, and most recently, on developing resistance — in the parasitic lice (Lepeophtheirus salmonis) that endanger both wild and farmed fish populations in the North Atlantic — to some of the chemical treatments used by aquaculturists to combat the parasite. The intense exploitation of wild fish and other marine creatures for human food (and as an ingredient in animal feeds) has caused, in recent decades, depletion of fish and seafood stocks across the world. The aquaculture industry — in which various aquatic species (fish, shellfish, and some plants) are bred, raised, and harvested in the open ocean — has grown rapidly as a response. Since the 1960s, the farming of salmon in the […]

(Beyond Pesticides, May 3, 2022) Exposure to a commonly used fungicide considered to be ‘slightly toxic or nontoxic’ to pollinators makes male mason bees less likely to find a mate, jeopardizing future generations of critically important pollinators. This determination comes from research recently published in the Journal of Applied Ecology by scientists at Germany’s University of Würzburg. The timing of these findings comes after the U.S. Environmental Protection Agency (EPA) reapproved uses of fenbuconazole, the fungicide in question, late last year without completing all required studies on pollinator health effects. Horned mason bees (Osmia cornuta), a solitary bee species, have a complex mating process that includes a range of “pre-copulatory behaviors” used by male bees attract females. Males create thoracic vibrations with their flight muscles, rub the eyes of female bees with their antennae, and emit a distinct odor from their body. If the female likes the presentation, she will mate with the male. Otherwise, she will move him to the side and wait for another male to try to win her affection. To see how this process was influenced by pesticide exposure, researchers conducted a range of different experiments. For the first, newly emerged male and female bees were […]

(Beyond Pesticides, April 28, 2022) A study in Environmental Research finds that glyphosate’s primary metabolite (breakdown product), aminomethylphosphonic acid (AMPA), induces DNA damage through oxidative stress among subpopulations of primary school children. Although pyrethroid and chlorpyrifos metabolites can induce oxidative stress, this study is the first to investigate AMPA’s association with adverse health effects, rather than solely the effects of the active ingredient, glyphosate, in Roundup and other formulations. Glyphosate is the most commonly used active ingredient worldwide, appearing in many herbicide formulations, readily contaminating soil, water, food, and other resources. Chemical use has been increasing since the inception of crops genetically modified to tolerate glyphosate. However, studies demonstrate glyphosate is among the most prevalent pesticide contributors to human, biotic, and ecosystem harm. According to research, herbicide toxicity to invertebrates has doubled since 2004. Although research links glyphosate exposure to cancer, specifically non-Hodgkin lymphoma, much less research considers the effects that metabolites have on children who are more vulnerable to chemical exposure. Ecological and health risk assessments primarily focus on active ingredients in pesticide products, overlooking the potential impacts of metabolites. Thus, studies like these highlight the need to assess the implications of metabolite exposure to protect human, animal, and environmental health. The study notes, “Our […]

(Beyond Pesticides, April 21, 2022) A literature review published in Royal Society finds that ‘inert’ ingredients’ in pesticide formulations adversely affect the health of bees and other wild pollinators. Inert ingredients, also known as “other” ingredients, and not disclosed by name on pesticide product labels, facilitate the action of active ingredients targeting a specific pest. Although both ingredients have chemical and biological activity, most studies on agricultural chemical toxicity focus on the active ingredient, assuming that inert ingredients are “nontoxic.” The U.S. Environmental Protection Agency (EPA), in regulating pesticides, assesses the toxicity of individual active ingredients on bees through various testing methods. However, there are no requirements for EPA to test inert ingredients to the same degree, despite evidence demonstrating these chemicals harm pollinators. Moreover, EPA does not require pesticide manufacturers to disclose the inert ingredients used in any product as the information is confidential. Both wild and commercial bees and other pollinators encounter multiple stressors, including pesticides, parasites, and poor nutrition, that act together to increase the risk of bee mortality. Therefore, reviews like these highlight the need for pesticide testing to consider the effects of all product ingredients, regardless of perceived toxicity. The researchers caution, “We argue that ‘inert’ ingredients […]

(Beyond Pesticides, April 20, 2022) A University of Michigan study is the first to highlight that maternal pesticide exposure during pregnancy adversely affects sleeping patterns for offspring later in life, specifically for females. Prenatal development is one of the most vulnerable periods of exposure as the fetus is most susceptible to the harmful effects of chemical contaminants. Many studies indicate that prenatal and early-life exposure to environmental toxicants increases susceptibility to diseases, from learning and developmental disabilities to cancer. However, the toxicity of pesticide exposure ad its full impact on the nonagricultural population in the U.S., especially women. Given research links to sleep-related disorders and neurological and cognitive development, studies like this can help government and health officials identify how pesticides’ impact on the brain elevates health concerns. The authors note, “Overall, these results are of public health importance considering the continued widespread agricultural and possibly residential use of pyrethroids and chlorpyrifos [in Mexico]…Thus, our results underline the importance of additional research studies that include both larger samples and assessment of unregulated pesticides, as well as studies that consider the underlying mechanisms explaining sex differences.” Levels of inadequate sleep patterns are rising among children and adolescents. Reports find variability in sleep duration results in higher rates of depression, anxiety, and […]

(Beyond Pesticides, April 19, 2022) Both houses of Maine’s legislature have just approved a bill that would, by 2030, ban pesticides that contain PFAS chemicals — the so-called “forever chemicals.” The bill’s next stop is the Appropriations Committee, for approval of $200,000 in annual funding to enact the bill; if successful there, it will move to the desk of Maine Governor Janet Mills for her signature. The legislation is one of a suite of lawmaker efforts in the state to address the growing PFAS problem with which localities across the U.S. are struggling. In this Daily News Blog article, Beyond Pesticides continues its coverage of the scourge of PFAS chemicals, particularly as it relates to pesticide use and the use of fertilizers made from PFAS-contaminated “biosludge” from municipal treatment facilities. PFAS — “per- and poly-fluoroalkyl substances” — are any of a family of more than 9,000 synthetic chemicals, invented in, and widely deployed since, the 1950s in a multitude of industrial and consumer products. PFAS molecules are made up of a chain of linked carbon and fluorine atoms; the carbon–fluorine bond is one of the strongest chemical bonds that exists, which means that these compounds do not break down in the […]

The organic solutions to problems highlighted in the latest issue of Pesticides and You—based on the importance of healthy ecosystems and public health protection—are within reach, and the data creates an imperative for action now that phases out pesticides within a decade, while ensuring food productivity, resilient land management, and safe food, air, and water. (Beyond Pesticides, April 15, 2022) The current issue of Pesticides and You, RETROSPECTIVE 2021: A Call to Urgent Action, is a look at a year of science, policy, and advocacy that informs both the existential problems that the U.S. and the world are facing due to toxic pesticide dependency, and solutions that can be adopted now. The information in this issue captures the body of science that empowers action at the local, state, and federal level, and provides a framework for challenging toxic pesticide use and putting alternatives in place. The issue finds that 2021 was a pivotal year in both defining the problem and advancing the solution. This year in review is divided into nine sections that provide an accounting of scientific findings documenting serious pesticide-induced health and environmental effects, disproportionate risk to people of color and those with preexisting conditions, regulatory failures, at the same time […]

(Beyond Pesticides, April 12, 2022) A recent study published in Scientific Reports warns that parasitic salmon lice (Lepeophtheirus salmonis) in Pacific Ocean open-net fish farming operations are becoming resistant to emamectin benzoate (EMB), an active ingredient used to control salmon lice population in North America, both in the U.S. and British Columbia, Canada. Previously, researchers believed parasitic salmon lice only had high rates of chemical resistance in the Atlantic region due to the mixing of farmed and wild salmon. However, Pacific salmon lice are exhibiting similar rates of decreased sensitivity to EMB from various sources, including a decrease in the wild Pacific salmon population, overuse of chemical treatments, and reliance on single chemical treatments. The aquaculture industry (e.g., farmed seafood/fish) repeatedly faces sustainability issues, failing to adhere to environmental regulations and threatening marine health. Extensive use of pesticides to rid the parasite has led to widespread resistance to multiple pesticides, prompting increasing infection rates among North Atlantic salmon populations. These parasites endanger both farmed salmon and wild salmon, in addition to other local species of fish. In this context, pesticide treatments contributes to resistance among lethal pest populations, especially in ecologically vulnerable and interconnected ecosystems like ocean basins. The researchers caution, “Salmon […]

(Beyond Pesticides, April 5, 2022) A meta-analysis by the Federal University of Technology – Paraná finds the herbicide 2,4-D causes indiscriminate harm, increasing the mortality rate among exposed animals. The severity of chemical exposure relies on species sensitivity, exposure rate, and lifecycle stage. However, commercial formulations of 2,4-D, commonly used in the environment, prompt a higher species mortality rate than technical (pure) 2,4-D alone. Like many other common herbicides such as glyphosate, 2,4-D has global uses that allow the chemical to accumulate in the environment, including soils, waterways, and tissues of non-target species. Therefore, meta-analyses like this help local and government officials make holistic decisions regarding environmental contaminants that incorporate conclusions from various studies. Using the Web of Science and Scopus databases, researchers compiled various studies (or meta-analyses) on the lethality of 2,4-D in different animal species (e.g., vertebrates, invertebrates). Researchers evaluated each study regarding the mortality rate of control and experimental groups, animal sensitivity to chemical exposure during a specific life stage, chemical formulation (e.g., commercial or technical), and exposure routes causing mortality. The analysis demonstrates that vertebrates experience higher mortality rates from 2,4-D exposure, with fish and birds presenting the highest mortality rate. Regarding life stages, larval and adult […]

(Beyond Pesticides, April 4, 2022) Recent actions by the U.S. Environmental Protection Agency (EPA) highlight the urgent need to prevent pesticides from further endangering crucial pollinators, including birds, bees, and bats. Tell EPA To Ban Neonics and Protect Against Other Threats to Pollinators. Tell Congress To Insist that EPA Does Its Job. Despite EPA’s own findings of evidence of serious threats posed by neonicotinoid (neonic) pesticides to pollinators, aquatic invertebrates, and other wildlife, it issued interim decisions on these neonics in January 2020 that disregard the science on the pesticides’ impacts and it appears that the agency is prepared to finalize these registrations late in 2022. This would, barring further action, extend the use of these harmful compounds for 15 years. Now is the time to let EPA know that continued use of neonicotinoids is unacceptable. Furthermore, building on a history of unenforceable and impractical pesticide label restrictions resulting in EPA findings of ludicrously small or no risk, the agency spun its approval of the continued use of the deadly organophosphate insecticide malathion as “protecting threatened and endangered species.” As the nation and world sit on the brink of biodiversity collapse and deadly pesticide-induced diseases, EPA actions continue to protect pesticide […]

(Beyond Pesticides, April 1, 2022) According to reporting by E&E’s Greenwire, internal emails at the U.S. Environmental Protection Agency (EPA) show that career scientists at the agency expressed worry about pesticide-laced pet collars, such as the notorious Seresto flea and tick collars, but that EPA managers “instructed them to avoid documenting those worries in publicly accessible records.” The emails were released pursuant to a 2021 FOIA (Freedom of Information Act) lawsuit, brought by the Center for Biological Diversity (CBD), that sought records of internal communications. The documents evidence staff concern about the collars that has not been a part of EPA’s public communications on the subject. EPA staff, in the emails, expressed a range of degrees of outrage at managers’ behavior and at the very registration of the product, given the significant harms. Seresto collars are plastic pet collars embedded with pesticides designed to kill fleas, ticks, and lice; they contain the active ingredients flumethrin and imidacloprid. Flumethrin, a chemical in the pyrethroid class of synthetic neurotoxic insecticides, has been linked repeatedly to neurological issues, such as seizures and learning disabilities in children, to gastrointestinal distress, and to damage to nontarget invertebrates, according to EPA’s own analysis. Imidacloprid is a commonly used pesticide linked to […]

(Beyond Pesticides, March 29, 2022) Plastic storage barrels contaminated with polyfluoroalkyl substances (PFAS) may be in violation of the Toxic Substances Control Act (TSCA), according to an open letter released by the U.S. Environmental Protection Agency (EPA) last month. Manufacturers, producers, processors, distributors, users, and those that dispose of fluorinated High-Density Polyethylene (HDPE) containers or other similar plastics that form PFAS as a byproduct were notified in the letter of requirements under federal law. The notice comes two years after EPA was first alerted to the presence of PFAS in a mosquito pesticide used by the state of Massachusetts known as Anvil 10+10. “Today’s action will help ensure that responsible parties are held accountable for any future PFAS contamination affecting communities,” said Assistant Administrator for the Office of Chemical Safety and Pollution Prevention Michal Freedhoff, PhD. While the agency believes its letter represents progress, health advocates note that there has been no meaningful regulatory action from the agency on this issue. In January 2021, a year after receiving notice from Public Employees for Environmental Responsibility (PEER) on the presence of PFAS on Anvil 10+10, EPA confirmed the finding. At the time the agency did nothing, while acknowledging, “the need to […]

(Beyond Pesticides, March 25, 2022) Recent coverage by The Guardian of the U.S. Environmental Protection Agency’s (EPA’s) plan — to extend the registration of several demonstrably harmful neonicotinoid insecticides — compels Beyond Pesticides to identify, once again, the agency’s failures to enact its core mission. That mission is “to protect human health and the environment,” and to ensure that “national efforts to reduce environmental risks are based on the best available scientific information.” EPA has undertaken a review of the registration of several members of the neonicotinoid (neonic) family of pesticides and, despite the agency’s own findings of evidence of serious threats to pollinators, aquatic invertebrates, and other wildlife, it issued interim decisions on these neonics in January 2020 that disregard the science on the pesticides’ impacts. EPA appears to be prepared to finalize these registrations late in 2022; this would, barring further action, extend the use of these harmful compounds for 15 years. Neonics are used widely in the U.S., both on crops to kill sucking insects, and as seed treatments with the same goal for the developing plant. These insecticides are systemic compounds, meaning that once applied, they travel to all parts of a plant through the vascular […]

(Beyond Pesticides, March 24, 2022) A range of essential oils can provide high levels of larvicidal and adulticidal activity against a commonly found species of mosquito, according to research published last week in Scientific Reports. The use of essential oils in mosquito management has generally been limited to personal protection, with synthetic pesticides often the first choice for vector control activities. This research highlights the potential role of these natural compounds to replace hazardous synthetics in managing larval sources and killing adult mosquitoes under last-resort scenarios. The team of Egyptian-based scientists conducting the study purchased 32 different essential oils from a regional retailer in order to test them on both the larval and adult stages of Culex pipiens. C. pipiens, often referred to as the common house mosquito, is the most abundant mosquito in the Northern U.S., and is known to vector West Nile virus and Saint Louis encephalitis, among other diseases. Larval efficacy was tested on the fourth instar larvae of C. pipiens, delivered through a mixture of the essential oil, water, and the solvent Tween-20, which contains the surfactant Polysorbate-20, used to emulsify the mixture. All oils tested had some level of larvicidal activity (between 60-100%). Researchers classified […]

(Beyond Pesticides, March 22, 2022) German cockroaches collected from U.S. residential homes have evolved resistance mechanisms so strong that many can consume ten times the pesticide required to kill a laboratory-susceptible strain and still not die. These are the findings of recent research published in the Journal of Economic Entomology, which focused on determining cockroach resistance levels to commonly used gel bait insecticides in infested Southern California homes. The findings underscore the importance of an integrated approach to cockroach management that recognizes and responds to pest ecology, rather than search for an ever-elusive silver bullet. Researchers collected five different strains of German cockroaches from various locations around Southern California, two from public housing and three from apartment dwellers. All sites had long-standing cockroach infestations, with varying treatment histories that generally included significant use of common gel bait insecticides. Tests were conducted on male cockroaches as they are gregarious foragers and thus more susceptible to baited food; it was indicated that if an insecticide cannot kill a male, it is highly unlikely to kill a juvenile or female roach. A separate group of cockroaches reared in the laboratory and never exposed to insecticides was used as a baseline for comparison. This […]

(Beyond Pesticides, March 21, 2022) With a history of unenforceable and impractical pesticide label restrictions resulting in U.S. Environmental Protection Agency (EPA) findings of ludicrously small or no risk, the agency is at it again with its latest announcement that spins its approval of the continued use of the deadly organophosphate insecticide malathion as “protecting threatened and endangered species.” This just the latest example of an irresponsible federal agency falling far short, as the nation and world sit on the brink of biodiversity collapse and deadly pesticide-induced diseases. Tell EPA to protect endangered species. Tell Congress to make sure the Biden administration protects endangered species.  The announcement follows the release of a final biological opinion by U.S. Fish and Wildlife Service (FWS), which, according to the Center for Biological Diversity (CBD), “relies on scientifically unfounded assessment methods imposed during the Trump administration [and] stands in sharp contrast to the agency’s 2017 conclusion that 1,284 species would likely be jeopardized by malathion.” Meanwhile, the National Marine Fisheries Service, a sister agency to the U.S. Fish and Wildlife Service, released an updated biological opinion that determined malathion and two other toxic organophosphate pesticides are causing jeopardy to virtually every endangered U.S. salmon, sturgeon, […]

(Beyond Pesticides, March 11, 2022) With a history of unenforceable and impractical pesticide label restrictions resulting in U.S. Environmental Protection Agency (EPA) findings of ludicrously small or no risk, the agency is at it again with its latest announcement that allows the continued use of the deadly organophosphate insecticide malathion. This just the latest example of what advocates see as an irresponsible federal agency falling far short, as the nation and world sit on the brink of biodiversity collapse and deadly pesticide-induced diseases.   In a head-spinning development, the U.S. Fish and Wildlife Service (FWS) announced on March 8 its final Biological Opinion (BiOp) on malathion, which opinion claims that the commonly used insecticide poses no extinction risk to any protected animal or plant. The FWS review and BiOp are part of EPA’s evaluation of whether malathion — an organophosphate insecticide that causes serious damage to many organisms — should retain its registration. The Executive Summary of the BiOp concludes: “Our findings suggest that no proposed species or candidate species would experience species-level effects from the action [i.e., registration and thus, permitted use of malathion], and, therefore, are not likely to be jeopardized. We also conclude the proposed action is not […]

(Beyond Pesticides, March 10, 2022) Glyphosate and glyphosate-based herbicides (GBH) like Roundup® induce DNA damage and alter biological mechanisms (gene regulatory microRNAs [miRNAs or miRs]) associated with cancer development. According to the study published in Toxicological Sciences, DNA damage mainly occurs through oxidative stress from GBH exposure. Moreover, DNA damage and other biological mechanisms that cause carcinogenicity (cancer) occur at doses assumed “safe” by pesticide regulators such as the U.S. Environmental Protection Agency (EPA). Glyphosate is the most commonly used active ingredient worldwide, appearing in many herbicide formulas, not just Bayer’s (formerly Monsanto) Roundup®. The use of this chemical has been increasing since the inception of crops genetically modified to tolerate glyphosate over two decades ago. The toxic herbicide readily contaminates the ecosystem with residues pervasive in food and water commodities. In addition to this study, literature proves time and time again that glyphosate has an association with cancer development, as well as human, biotic, and ecosystem harm.  Study lead author Michael Antoniou, Ph.D., cautions, “Our results are the first to simultaneously show glyphosate and Roundup toxicity in a whole mammalian animal model system and provide a mechanism – oxidative stress – by which DNA damage has been observed in other systems, such as mammalian […]

(Beyond Pesticides, March 9, 2022) In response to local concerns around children’s environmental exposures, the Minnesota Department of Health (MDH) recently published biomonitoring data collected from young children living in urban and rural areas of the state. The findings provide local residents and lawmakers with baseline data on the hazards children are encountering where they live, learn, or play, and point to ways in which families can reduce or eliminate these dangers. With evidence that early life exposures during “critical windows of vulnerability” increase risk of long-term health problems, it is critical for state agencies to both collect data, and take meaningful action to protect children from future harms. Minnesota lawmakers established a state biomonitoring program in 2007, and have since expanded the project. The current report represents the results of MDH’s Healthy Rural and Urban Kids Project aimed at biomonitoring chemicals in young children. For this round, the agency focused on preschool-aged children living in MN’s rural Becker, Todd, and Wadena counties, as well as those living in urban North Minneapolis. MDH enrolled 232 families during the summer of 2018, provided them with a questionnaire, and tested children for 21 different chemicals in their urine. The chemicals tested were […]

(Beyond Pesticides, March 4, 2022) An article in My London reported by Finn Byrne, finds labeling on conventionally grown fruits and vegetables marked as non-vegan. The non-vegan label shocked many shoppers who buy the produce with chemical-intensive practices, as fruits and vegetables are inherently vegan. However, pesticides used in the production of fruits and vegetables render these foods non-vegan because of the harm that pesticides cause to animals and since a wax coating on fruits and vegetables made of shellac, a resin secreted from female lac beetles and thus non-vegan. Recent studies indicate plant-based diets can mitigate excessive pesticide use and exposure if they are organically grown. However, a plant-based diet reliant on pesticides does little to lessen the health and ecological effects of conventional agriculture. Fungicides are ubiquitous in agricultural and residential settings puts human and animal health at risk. Exposure to fungicides can manifest adverse health effects, including reproductive dysfunction, birth/developmental effects, kidney/liver damage, and cancer. Several researchers find that fungicide use promotes more drug-resistant fungal infections in humans as these fungicides are structurally similar to medical antifungal medications. After investigating fruits and vegetables at various United Kingdom (UK) grocery stores (i.e., Tesco, Morrisons, and Marks and Spencer), the report finds fungicides imazalil and propiconazole present […]

(Beyond Pesticides, March 3, 2022) Children’s exposure to synthetic pyrethroid insecticides, particularly during the course of mosquito control operations, is associated with increased occurrence of certain respiratory diseases and allergic outcomes, finds research published in the journal Thorax late last month. With a pandemic respiratory virus continuing to spread throughout the world, it has become increasingly important to avoid environmental exposures that can harm lung health. This research underscores the critical need for homeowners, farmers, and vector control officials to shift away from chemical use as the first line of defense against pest problems in order to safeguard children’s health. A total of 303 women and their children participated in the study, which tracked pesticide exposure during pregnancy and then at age five. All participants in the study lived within roughly three miles of a banana plantation. A structured questionnaire captured a range of variables, from socioeconomic status to medical history, local environmental conditions, occupation, and demographics. Researchers collected urine samples from pregnant mothers during the first visit, and their children during the 5-year follow-up. Urine samples were analyzed for metabolites concerning a range of pesticides, including chlorpyrifos, synthetic pyrethroids, the fungicides mancozeb, pyrimethanil, and thiabendazole, and the herbicide 2,4-D. […]