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Daily News Blog

Archive for the 'Chemicals' Category


31
Oct

Environmental Toxicants, including Pesticides, Linked to Parkinson’s Disease

(Beyond Pesticides, October 31, 2025) A review in Lancet Neurology provides a clear snapshot of the state of scientific understanding of Parkinson’s disease and how medicine and policy could be improved by shifting focus to the primary causes of the disease, namely environmental toxicants, and to emphasize prevention rather than devoting resources only to treatments and a cure. The study, led by Ray Dorsey, M.D. of the Atria Research and Global Health Institute and the University of Rochester Medical Center, focuses on three classes of environmental toxicants: pesticides, dry cleaning and degreasing chemicals, and air pollution. Because these are pollutants introduced by humans, the authors say, they should be controllable, and “Parkinson’s disease could be thus largely preventable.” According to the review, in the last five years, new evidence has accumulated about three types of pesticides of particular concern. They are not all insecticides, which is the pesticide category most associated with neurological damage. Paraquat is a herbicide used on corn, soybeans, and cotton. Rotenone is used to kill rats and insects. Organochlorine insecticides comprise the third class. The review notes that there are many other pesticides that are neurotoxic and may have common mechanisms of action leading to Parkinson’s and […]

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30
Oct

Hyperactive Behavior in Preschoolers Linked to Endocrine Disrupting Chemical Exposure

(Beyond Pesticides, October 29, 2025) A study published in Environment International evaluates residues of individual and mixtures of endocrine-disrupting chemicals (EDCs), including pesticides, and finds an association between exposure and hyperactive behavior in children. The researchers evaluated urine samples from over 800 preschoolers, identifying and statistically analyzing concentrations of 22 EDCs, and finding that nine of these chemicals are significantly associated with hyperactivity trajectories and EDC mixtures are positively associated with hyperactive behavior, noting the strongest association in girls.  “The current study indicates the adverse health effects of exposure to mixtures of EDCs among preschoolers, and suggests gender specificity in these effects,” the researchers state. They continue, “This highlights the importance of focusing on multi-pollutant exposure in early childhood.”  Study Importance  “Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children, which has become one of the main factors leading to the burden of disease in children and adolescents worldwide.” The authors continue: “Its core symptoms are high levels of inattention and/or hyperactivity/impulsivity during the preschool period. A meta-analysis showed that the overall prevalence of ADHD in children in China over the past 15 years was as high as 6.2%, and has been increasing over recent years.”  In comparison, according […]

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28
Oct

Organophosphate Pesticide Drift from Agricultural Fields Elevates Risk for Pregnant Farmworkers

(Beyond Pesticides, October 28, 2025) A California-based population study published in BMC Public Health finds that “7.5 [percent] of all pregnant people in California who gave birth in 2021 lived within 1 km [kilometer] of agricultural fields where OP pesticides [organophosphates] had been used during their pregnancy. . .” Despite a 54 percent decrease in overall use of the neurotoxic insecticide chlorpyrifos in the state between 2016 and 2021, after a statewide ban on the organophosphate insecticide in 2016, researchers found that in one California county, “more than 50 [percent] of pregnant people lived within 1 km of OP pesticide use.” Significant disparities were found in terms of elevated exposure to pesticides, “with Hispanic/Latine, young people, and residents of the predominantly fruit and vegetable growing Central Coast region being most likely to live near OP pesticide applications during pregnancy.” The authors suggest that “regulatory changes to limit use or restrict applications in close proximity to residential areas could have a substantial public health benefit on children’s brain development.” These findings add to the existing scientific literature on perinatal and maternal pesticide exposure associated with adverse long-term health effects for children and mothers. They also serve as a reminder to public […]

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27
Oct

Beyond Pesticides Campaigns to Stop Use of Toxic Sewage Sludge (Biosolids) Fertilizer, Transition to Organic

(Beyond Pesticides, October 27, 2025) With the confluence of science and law, the spotlight is on sewage sludge fertilizer and its contaminants, including per- and polyfluoroalkyl substances (PFAS). Sewage sludge (biosolids) is a byproduct of sewage treatment and is used as a source of organic matter for amending soil in nonorganic agriculture and landscaping. In light of a recent settlement in a lawsuit filed by Beyond Pesticides against ScottsMiracle-Gro, ongoing litigation against GreenTechnologies, LLC, and a major study identifying 414 contaminants of emerging concern (CECs), Beyond Pesticides’ network is calling on Governors and local officials to ban the use of biosolids on farms and parks, until there is adequate testing of toxic residues—which does not currently exist.   The lawsuits against producers of sewage sludge fertilizer cite test results showing PFAS residues in the companies’ products and numerous scientific studies on the adverse effects of PFAS to public health, wildlife, and pollinators. (See settlement statement recently reached with ScottsMiracle-Gro.)  A literature review published in Frontiers in Environmental Chemistry identifies CECs in soils, untreated and treated sewage sludge (biosolids), and dust, across 151 peer-reviewed studies released between 2018 and 2023—emphasizing the range of potential exposure pathways across various products, including classes of pesticides like neonicotinoid insecticides. […]

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24
Oct

Childhood, Prenatal Pesticide Exposure Impacts Immune System, According to Study

(Beyond Pesticides, October 24, 2025) A literature review published in Science of the Total Environment reports numerous peer-reviewed studies associating prenatal and childhood pesticide exposure to measurable alterations to children’s immune systems, including indicators of immunosuppression and increases in pro-inflammatory cytokines, among other adverse health effects. These immune system alterations are linked to higher infection risk and potentially contribute to autoimmune diseases and allergies later in life. For over four decades, Beyond Pesticides has tracked the peer-reviewed science and identified a preponderance of evidence linking pesticide and chemical-dependent pest management to adverse human and ecological health effects. In this spirit, public health and environmental advocates continue to call for a wholesale transition to organic land management and organic pest management as biodiversity, public health, and climate crises continue to mount. This mission supports the growth of the Parks for a Sustainable Future Program, where nineteen cities in eleven states across the country engage in pilot projects to transition parks, playing fields, and schoolyards to organic management practices and protect the health of children. Background and Methodology “This study aimed to evaluate the extent of immunotoxicity and correlation between exposure to pesticides and immune system alterations in children under five years […]

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23
Oct

Pesticide Contamination of Seaweed Threatens Public Health, Biodiversity, and Ecosystem Functioning

(Beyond Pesticides, October 23, 2025) A global literature review of pesticide residues in marine seaweed, published in Marine Pollution Bulletin, highlights the widespread presence of pesticides in bioindicator species. As vital coastal primary producers, seaweed acts as a key indicator for regional pesticide contamination patterns. The bioaccumulation within seaweed species also threatens consumers, including humans, as the chemicals can biomagnify as they move through the food web. Pesticide contamination in waterways allows residues to bioaccumulate in seaweed species, presenting risks to public health, biodiversity, and ecosystem functioning. In addition to the support seaweeds provide for ecosystems, they provide food sources for a multitude of organisms and are of growing socioeconomic importance. “This systematic review identifies, critically evaluates, and synthesizes recent global literature (2015–2024) on pesticide residues detected in seaweeds to delineate contamination patterns,” the authors share. The findings highlight the harmful impacts of petrochemical pesticides on multiple species. Many aquatic species rely on seaweed as a food source, including fish, sea urchins, crabs, snails, brittle stars, and marine mammals such as manatees and sea turtles. Even bacteria and filter feeders consume seaweed when it is decomposed. Birds and land mammals also consume seaweed, including humans who utilize seaweed in various […]

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21
Oct

Dietary Pesticide Exposure Study Stresses Need for More Accurate Assessment

(Beyond Pesticides, October 21, 2025) A study, published in International Journal of Hygiene and Environmental Health, calculates cumulative dietary pesticide exposure and finds a significant positive association between pesticide residues in food and urine when analyzing over 40 produce types. The research uses data for 1,837 individuals from the 2015–2016 National Health and Nutrition Examination Survey (NHANES) and compares them to biomonitoring samples of the participants. According to the researchers, “Here we show that consumption of fruits and vegetables, weighted by pesticide load, is associated with increasing levels of urinary pesticide biomarkers.” They continue, “When excluding potatoes, consumption of fruits and vegetables weighted by pesticide contamination was associated with higher levels of urinary pesticide biomarkers for organophosphate, pyrethroid, and neonicotinoid insecticides.” The NHANES data is derived from a national biomonitoring survey from the U.S. Centers for Disease Control and Prevention (CDC), which collects information about consumption of fruits and vegetables as well as urine samples. Background As the study authors explain: “Hundreds of millions of pounds of synthetic pesticide active ingredients are used every year in the United States, and pesticide exposure can occur through food, drinking water, residential proximity to agricultural spraying, household pesticide use, and occupational use. Pesticide […]

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20
Oct

Escalating Bacterial Resistance Supports Call for Antibiotic Pesticide Ban in Agriculture and Synthetic Turf

(Beyond Pesticides, October 20, 2025) With the release of a study that links the use of nitrogen fertilizer in combination with antibiotic pesticides to escalating bacterial resistance, public health advocates are renewing their call for the U.S. Environmental Protection Agency (EPA) and the U.S. Congress to eliminate antibiotic pesticide use in land management. This action comes on the heels of a World Health Organization (WHO) study finding that antibiotic resistance is evolving even faster than previously thought. WHO finds, “One in six laboratory-confirmed bacterial infections causing common infections in people worldwide in 2023 were resistant to antibiotic treatments. . .. Between 2018 and 2023, antibiotic resistance rose in over 40% of the pathogen-antibiotic combinations monitored, with an average annual increase of 5–15%.”  These findings, linking pesticides, antibiotics, and nitrogen fertilizers to antibiotic resistance, again raise serious concerns about the deadly impacts of conventional (chemical-intensive) agricultural practices on human health. The researchers found that nitrogen is a strong driver of resistance processes. The richness and diversity of phages—viruses that attack bacteria and can transmit antibiotic resistance genes (ARGs)—is highest in the groups exposed to both nitrogen and combined pesticides, and the abundance of ARGs in phages becomes “markedly elevated” in those same exposure conditions.  Bacterial […]

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16
Oct

Combination of Pesticide and Nitrogen Use in Agriculture Escalates the Spread of Antibiotic-Resistant Bacteria

(Beyond Pesticides, October 16, 2025) An important new study links pesticides, antibiotics, and nitrogen fertilizers to the extreme global crisis of antibiotic resistance, raising serious concerns about the adverse impacts of conventional (chemical-intensive) agricultural practices. The research team, from several Chinese universities and laboratories and Queen’s University in Belfast, conducted a three-year study in China using soil bacteria and phages (bacteriophages, or viruses that invade bacteria) from an experimental field, exposing them to a variety of conditions ranging from the control (no exposures) to various combinations of nitrogen fertilizer and two categories of pesticides (the insecticide chlorpyrifos and a blend of the fungicides azoxystrobin and propiconazole). Phages are viruses that eat bacteria. They invade the bacterial cell and, in various ways, cause the death of the bacterium. Some viral genes cause the cells to lyse, or dissolve, releasing their genetic material into the surrounding environment, where other organisms can pick up new genes. In this way, phages are a major pipeline for horizontal gene transfer (movement of genes in bacteria from one bacterial species to another) among microbes. This phenomenon is of increasing concern because the genes circulating in this marketplace include many that enhance antibiotic resistance. The researchers were […]

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15
Oct

Report on Pesticide Contamination of Nation’s Groundwater Shows Widespread Exposure and Health Threats

(Beyond Pesticides, October 15, 2025) The latest Scientific Investigations Report for 2025 from the U.S. Geological Survey (USGS), entitled “National Water Quality Program: Multidecadal Change in Pesticide Concentrations Relative to Human Health Benchmarks in the Nation’s Groundwater,” finds moderate concentrations of five pesticides, with the highest percentages in agricultural wells, and concentrations of the carcinogenic soil fumigant DBCP (1,2-dibromo-3-chloropropane), which also causes infertility, that are greater than the maximum containment level, despite being banned over 45 years ago. These results highlight the persistence of pesticides used in agriculture and the elevated risks of pesticide contamination in agricultural areas. This report monitors concentrations of pesticides in well networks across the U.S. in decadal intervals, with this last one incorporating data ranging from 1993-2023. Additionally, DBCP in one well network in the San Joaquin-Tulare River Basin in California continues to be assessed due to previous levels exceeding the human health benchmark (HHB) established by the U.S. Environmental Protection Agency (EPA). The limitations of the study are disclosed in the text of the report. As the authors state: “Only pesticides with an HHB were included in the multidecadal pesticide change analysis… The total number of pesticides included in this study is less than […]

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07
Oct

Lower Pesticide Exposure Documented for Organic Farmers, Elevated for Others

(Beyond Pesticides, October 7, 2025) Published in Environment International, a study utilizing silicone wristbands provides a snapshot of chemical exposure in over 600 participants across 10 European countries. Using the wristbands as passive and noninvasive samplers, the researchers find that organic farmers’ wristbands contain lower pesticide levels than other groups, offering insight into the benefits of organic and disproportionate risks to farmers using chemical-intensive methods. The results further reveal prevalent environmental pesticide mixtures, in addition to highlighting exposure to current-use pesticides (CUPs) and legacy (banned) pesticides that occurs through multiple exposure routes to workers, residents, and consumers. “Our study offers a comprehensive analysis of non-dietary pesticide exposure patterns among various populations across the EU [European Union], underscoring its widespread prevalence and identifying significant occupational and residential predictors,” the authors explain. As pesticide exposure occurs through both dietary and nondietary routes, such as through dermal (skin) contact and inhalation of contaminated air, there “is a growing need for aggregated [total; combined] exposure estimates across occupationally and nonoccupationally exposed populations.” The study includes testing for 193 pesticides, both legacy pesticides and CUPs, captured in silicone wristbands worn by farmers, residents living close to treated fields (neighbors), and the general population (consumers) in […]

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02
Oct

With State Legislation Focused on Restricting Bee-Killing Pesticides, Advocates Call for Organic Transition

(Beyond Pesticides, October 2, 2025) This year marks an advancement of various state-level neonicotinoid laws and regulations, including in Maine, Vermont, and Connecticut—emphasizing surging public support for pesticide reforms. The Maine legislature passed, and Governor Janet Mills (D-ME) signed into law on July 22, 2025, LD 1323, which commissions the Board of Pesticide Control to study the impacts of neonicotinoids and neonicotinoid-treated seeds, which advocates hope will help advance future legislation to prohibit the use, distribution, and sale of neonicotinoid insecticide products. Meanwhile, after years of grassroots advocacy, the Connecticut legislature advanced, and Governor Ned Lamont (D-CT) signed SB 9 into law, which will partially restrict the nonagricultural use of neonicotinoids on turfgrass, starting in 2027. There was a more comprehensive effort that failed to move forward (HB 6916), which would have gone further by restricting or prohibiting the use of neonicotinoids on trees, shrubs, and treated seeds (see here for Beyond Pesticides comments). Maine and Connecticut join eleven other states (California, Nevada, New Jersey, Massachusetts, Maryland, Minnesota, New York, and Vermont) in taking steps to restrict or prohibit the use of neonicotinoids. (See Daily News here.) Whether it is a campaign to ban glyphosate, paraquat, chlorpyrifos, atrazine, or any […]

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01
Oct

Study Reveals Mechanisms of Kidney Injury and Cancer from Exposure to Weed Killer Glyphosate

(Beyond Pesticides, October 1, 2025) A novel study in Scientific Reports combines computational analyses with toxicological data to identify pathways affected by exposure to the weed killer glyphosate. The analyses identify glyphosate targets that correlate with kidney injury and kidney cancer, revealing pathways with significant glyphosate-induced alterations, including the dysregulation of nitrogen metabolism that leads to ammonia accumulation and oxidative stress, both of which contribute to renal (kidney) damage and carcinogenesis (development of cancer). “This study provides a comprehensive investigation into the molecular mechanisms by which glyphosate may contribute to kidney injury and kidney cancer, employing an array of bioinformatics tools for target prediction, toxicity assessment, pathway enrichment analysis, molecular docking and molecular dynamics simulation,” the researchers state. The results of the analyses and simulations highlight the molecular mechanisms underlying glyphosate’s nephrotoxic (damaging to kidneys) and carcinogenic (cancer-causing) effects. Study Importance and Background Glyphosate, known as a broad-spectrum systemic herbicide, has been used for agricultural and nonagricultural purposes for decades and is the most extensively used herbicide worldwide. This widespread use is largely due to its application to genetically engineered, glyphosate-tolerant crops. Both glyphosate and its main metabolite (breakdown product), aminomethylphosphonic acid (AMPA), are detected in water, soil, and food, […]

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30
Sep

Transport of Pesticides in Clouds Causes Transcontinental Contamination, Study Finds

(Beyond Pesticides, September 30, 2025)  A pioneering study has measured the concentrations of pesticides in clouds. Prior to this, rainwater has been tested and found to be a common depositor of pesticides. But there is far less information about the role of clouds themselves. The findings add to general scientific understanding that pesticides go everywhere: into soils, water bodies, and the bodies of plants and animals—even when they are not intentionally applied. There are many studies of pesticide concentrations, including their metabolites, so-called “inert” ingredients, and degradation products, in soil, water and the atmosphere. The study was published in Environmental Science & Technology last August by a team of scientists from the University of Clermont Auvergne and the Laboratoire Phytocontrol in France and the University of Torino in Italy. Clouds are collections of water droplets, as opposed to molecular gases or aerosols, which are simply fine particles or liquid droplets of any substance capable of becoming airborne. Aerosol and gas-phase chemicals are known to travel widely in the atmosphere and do not require the presence of water to do so. Contaminants in rain have been studied to some extent, but rain is a separate analytical category from clouds. A study […]

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25
Sep

PFAS, Pesticide, Pharmaceuticals, and Heavy Metals Found in Backyard Eggs Underscore Toxic Threat

(Beyond Pesticides, September 25, 2025) Reinforcing numerous studies’ findings of widespread environmental contamination with PFAS (per- and polyfluoroalkyl substances), heavy metals, pesticide metabolites, and pharmaceuticals, researchers detected the chemicals in noncommercial backyard eggs laid in Greece, according to a study published in Science of The Total Environment. The researchers found that “[o]nly 9 out of 17 samples were compliant to the limit….set by the [European Union] for the sum of PFHxS [perfluorohexanesulfonic acid], PFOS [perfluorooctanesulfonic acid], PFOA [perfluorooctanoic acid], and PFNA [perfluorononanoic acid].” They continue: “[A]s regards PFOS, PFHxS, and PFNA, seven, six and one out of 17 samples, respectively, were above the ML (maximum limit) as set by the EU.” With current regulatory standards focused on evaluating exposure to individual chemicals and, in some instances, cumulative risk associated with chemicals that have a common mechanism of effect, this study points out the importance of looking at mixtures of chemicals and the potential synergistic effects. There are some fluorinated pesticides defined as PFAS due to their molecular structure and high toxicity, which makes the chemicals highly persistent in the environment. Center for Food Safety, Center for Biological Diversity, and Public Employees for Environmental Responsibility reviewed the full list of active […]

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24
Sep

Neonicotinoid Insecticide Linked to Honey Bee Decline, Threatening Reproductive Function of Hive

(Beyond Pesticides, September 24, 2025) A novel study of chronic toxicity of the neonicotinoid insecticide thiamethoxam to honey bees (Apis mellifera), published in Insects, finds sublethal effects that threaten the survival of bee larvae and the health of bee colonies. “We evaluated the effects of thiamethoxam on the entire larval development cycle of reproductive bees and conducted a comparative analysis, demonstrating that thiamethoxam significantly alters ecdysone [a hormone that controls molting in insects] and juvenile hormone titers [hormones for insect growth] in both queen and drone larvae, impairing metamorphosis and reproductive development,” the authors state. Risk assessments and scientific literature focus primarily on honey bee workers, rarely including how pesticides can impact queen and drone bees that are necessary for stable colonies. In focusing on this data gap, the researchers reveal that the survival rate of bee larvae decreases gradually with increasing doses of thiamethoxam, adding to the wide body of science on pesticide-related threats to honey bee health. (See Beyond Pesticides’ What the Science Shows on Biodiversity page for more information, as well as Daily News coverage on risk assessments here, here, and here.) Honey bees provide crucial ecosystem services as pollinating insects and play a vital role in […]

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19
Sep

Agricultural Pesticide Residues in River–Lake Systems Threaten Nontarget Organisms in Aquatic Ecosystems

(Beyond Pesticides, September 19, 2025) In Water Science and Engineering, a study investigating the occurrence and distribution of agricultural pesticides in a river–lake system of the Taihu Lake Basin in China through surface runoff finds adverse effects on nontarget organisms that threaten ecological security. In evaluating the risks to aquatic organisms, the researchers highlight how pesticide residues in surface water and sediments jeopardize the entire food web, as risks are present throughout multiple trophic levels (positions in the food chain). The results show that in surface waters, the fungicide carbendazim is the dominant pollutant with 23.66% of the contamination. Within the sediment samples, the fungicide tebuconazole is the primary contributor at 28.57%. Overall, fungicides are the main type of pesticide present in the tested river water and sediments. These compounds account for 76.86% and 85.10% of contamination, respectively. The authors also note that pesticide concentrations in both water and sediments in the rivers increase while moving downstream. “Ecological risk assessment revealed high mixed risks to algae, daphnia [water fleas], and fish, with risk levels rising along with trophic levels of aquatic organisms,” the researchers state. They continue, “[C]ertain pesticides posed high risks to algae even at low concentrations, indicating more […]

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18
Sep

Study of Earthworms Finds Fluorinated Pesticides Threaten Soil Ecosystems

(Beyond Pesticides, September 18, 2025) Published in Environmental Toxicology and Pharmacology, a study of earthworms (Eisenia fetida) evaluates the toxicity of environmentally relevant levels of three fluorinated pesticides (fluxapyroxad, fluopyram, and bixafen) through a 56-day soil exposure experiment. The dose- and time-dependent results reveal that effects on growth and reproduction occur at elevated concentrations, with weight loss and reduced offspring occurring from energy depletion and reproductive organ damage. Other implications escalate with concentration as well, including antioxidant system failure and DNA damage. As the authors summarize, “These findings highlight the mechanisms of fluorine-containing pesticide toxicity in earthworms, emphasizing their potential to disrupt soil ecosystems.” Fluorine-containing pesticides are widely used in agriculture, yet the chronic effects on soil and soil organisms are not fully considered in regulatory review. Research comparing the similarities and differences in the impacts on nontarget organisms from fluorinated pesticides is lacking, with the current study beginning to address the urgent need to close this gap. “Data indicate that among more than 100 newly developed pesticides, fluorine-containing pesticides constitute nearly half, making them a focal point in the development of the global pesticide industry,” the researchers state. As representatives of the fluorinated pesticides class, particularly succinate dehydrogenase inhibitors […]

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17
Sep

Study of Biological Diversity Effects of Pesticide Mixtures Highlights Underestimated Risks to Ecosystems

(Beyond Pesticides, September 17, 2025) A study in Environmental Science & Technology finds additive effects of a synthetic pyrethroid insecticide (cypermethrin) and two fungicides (azoxystrobin and prochloraz) on biological control, biomass of major invertebrate trophic groups (position in food web), and soil ecosystem processes in arable systems (land suitable for growing crops). The study authors further highlight the failure of pesticide regulations to consider elaborate trophic interactions and pesticide mixtures, as well as additive and synergistic effects within their assessments, calling attention to the complexity of real-world exposures and the lack of research to fully understand the implications of chemical use for agricultural and land management purposes. “Arable systems have a high dependence on diverse natural biota to support pest control, soil bioturbation, and nutrient recycling,” the researchers write. These communities rely on a balance of organisms within various trophic levels in order to function and provide vital ecosystem services. Disruptions caused by environmental contaminants, such as pesticides to nontarget organisms, impact entire ecosystems and overall biodiversity. As the authors state, current risk assessments underestimate the real-world risks of petrochemical pesticides and synthetic fertilizers that, despite a wide body of science connecting exposure to deleterious health and environmental effects, are […]

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15
Sep

Group Urges Regulation of Weed Killer Glyphosate, Found in Food Supply, for Its Synergistic Effects

(Beyond Pesticides, September 15, 2025) With residues of the widely used weed killer glyphosate (Roundupᵀᴹ) in the food supply long documented, scientific attention has turned to the synergistic effects of the weedkiller— a magnified effect greater than the individual chemical effects added together. The authors of an article in World’s Poultry Science Journal write, “The synergistic toxic effects of commercial glyphosate formulations and their bioaccumulation in animal tissues are often overlooked in current safety assessments.” Following up on a previous action, Beyond Pesticides is telling Congress and the U.S. Environmental Protection Agency (EPA) that the agency must consider the effects of pesticides in the context in which they are used and promote the organic alternative.  Glyphosate residues in animal feed, as well as in water and through other exposure routes from food generally and residential areas, pose risks to both animal and human health, as these residues can bioaccumulate. As previously examined by Beyond Pesticides, the effects of pesticides are not limited to the crops to which they are applied. Synergistic effects of multiple chemical exposures are the rule, rather than the exception.   With poultry, the herbicide enters the production system through residues in genetically engineered feed. An earlier article in Scientific Reports concludes that glyphosate’s […]

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12
Sep

Study Adds to Science Showing Elevated Toxicity Linked to Pesticide Mixtures

(Beyond Pesticides, September 12, 2025) A team of Argentinian researchers conducted a study published in Environmental Toxicology and Pharmacology of the combined effects of the herbicide glyphosate and the pyrethroid insecticide cypermethrin. The researchers observed significantly higher apoptosis in cells exposed to the mixtures than to the individual pesticides—a synergistic response. Apoptosis, also known as programmed cell death, is a standard way that tissues handle damaged cells to remove threats to their function. The researchers sought to investigate the cellular toxicity of each chemical, individually and in combination, and assessed whether the effects of the mixture were additive or synergistic. Additive effects occur when two individual chemicals amplify the same sort of response, often because the chemicals have similar structures. Synergism can occur when chemicals have different mechanisms of action but work together to create more powerful effects. Mixtures of pesticides are the least-studied area of research conducted for regulatory purposes. While regulators provide instructions to applicators regarding which pesticides can be applied together and combined in tank mixtures, there is no control over how pesticides travel through the environment once applied, as they flow through the air as spray drift, lodge in soils and water, and are incorporated into […]

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10
Sep

MAHA Strategy Report Backs Off Pesticides After Defining Serious Threat in Earlier Assessment

(Beyond Pesticides, September 10, 2025) After being criticized by the chemical industry and allied agribusiness and service industry groups on the Make America Healthy Again (MAHA) report in May, the strategy document, released yesterday, has tamped down efforts to reform government programs that regulate pesticides. There are no specific recommendations on improving the regulation of pesticides. Rather, the strategy appears to embrace business-as-usual and could even ramp up government efforts to tout the need for pesticides and claims that current regulatory reviews are effective and comprehensive. In a section of the strategy entitled “Increasing Public Awareness and Knowledge,” the document says: “EPA, partnering with food and agricultural stakeholders, will work to ensure that the public has awareness and confidence in EPA’s pesticide robust review procedures and how that relates to the limiting of risk for users and the general public and informs continual improvement.” This is at odds with the earlier MAHA assessment report which identified pesticides as substances of concern that, citing deficiencies in chemical reviews, “may be neglecting potential synergistic effects and cumulative burdens, thereby missing opportunities to translate cumulative risk assessment into the clinical environment in meaningful ways.” While the earlier report, Make Our Children Healthy Again: Assessment, […]

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09
Sep

California Launches Updated Notification of Pesticide Spraying, Farmworkers Call for Organic on Fields Near Homes and Schools

(Beyond Pesticides, September 9, 2025) SprayDays California, the pesticide notification and mapping tool run by the California Department of Pesticide Regulation (DPR), was updated in late August after public backlash (including from farmworkers), which identified inadequate notice of pesticide use to those who work in or live in proximity to agricultural fields. According to a DPR press release from August 28, these changes include attempts to bring down barriers for users so that, in the words of DPR Director Karen Morrison, the department can “provide Californians with access to information and services.” While public health advocates view notification as a step that may allow people to leave a treatment area or take shelter to reduce exposure, groups continue to express concerns about a focus on notification to the exclusion of addressing the root causes of exposure—chemical-intensive agriculture, despite the viability of organic compatible practices and products. The groups criticize the continuous registration of pesticide active ingredients and product formulations without considering widely available practices and nonchemical and nature-based alternatives to pest management. These include regenerative organic principles and practices that draw inspiration from Indigenous land management and agroecological systems that have thrived in coexistence with nature. Recent Updates There are […]

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