(Beyond Pesticides, March 5, 2009) A new study published in the March 2009 issue of Environmental Health Perspectives finds that pesticide combinations cause more harm to endangered salmon than ndividual pesticide exposure. This means that single-pesticide risk assessments required by the Environmental Protection Agency (EPA) inadequately assess hazards. Mixtures of organophosphate and carbamate pesticides are commonly detected in freshwater habitats that support threatened and endangered species of Pacific salmon. According to the researchers from the National Oceanic and Atmospheric Administration (NOAA) Fisheries and Washington State University, these pesticides inhibit the activity of acetylcholinesterase (AChE) and thus have potential to interfere with behaviors that may be essential for salmon survival. The researchers measured brain AChE inhibition in juvenile coho salmon exposed to sublethal concentrations of the organophosphates diazinon, malathion, and chlorpyrifos, as well as the carbamates carbaryl and carbofuran. The pesticides were tested individually and in combination. They plotted AChE levels on a curve to determine whether the toxicologic responses to binary mixtures were additive, antagonistic (lesser than additive) effect, or synergistic (greater than additive). The authors observed addition and synergism, with a greater degree of synergism at higher exposure concentrations. Several combinations of organophosphates were lethal at concentrations that were […]

(Beyond Pesticides, March 4, 2009) The Ontario government is set to announce sweeping new regulations that will prohibit the use of 85 chemical substances, found in roughly 250 lawn and garden products, from use on neighborhood lawns. Once approved, products containing these chemicals would be barred from sale and use for cosmetic purposes. On November 7, 2008, the Ontario government released a proposed new regulation containing the specifics of the Cosmetic Pesticides Ban Act, passed last June. Then, Ontario joined Quebec in restricting the sale and cosmetic use of pesticides but environmental and public health advocates said then that the new law preempted local by-laws and actually weakens protections in some municipalities with stronger local protections. There are over 55 municipalities in Canada where the residential use, but not sale, of pesticides is banned. The prohibition of these 85 substances is the latest step in this Act. The proposal contains: ”¢ List of pesticides (ingredients in pesticide products) to be banned for cosmetic use ”¢ List of pesticide products to be banned for sale ”¢ List of domestic pesticide products to be restricted for sale. Restricted sale products include those with cosmetic and non-cosmetic uses (i.e., a product that’s allowed […]

(Beyond Pesticides, March 2, 2009) Pesticide exposure and genetic variability in the dopamine transporter (DAT), a protein that plays a central role in dopaminergic neurotransmission of the brain, interact to significantly increase the risk factor for Parkinson’s disease, according to a new study by University of California, Los Angeles (UCLA) researchers. The population based case-control study, “Dopamine Transporter Genetic Variants and Pesticides in Parkinson’s Disease,” builds on the existing body of evidence of animal data and epidemiological studies that link exposure to pesticides, including gene-pesticide interactions, to Parkinson’s disease. The UCLA researchers, looking at incident Parkinson’s disease cases in three rural counties in Central California, find DAT increases the risk of Parkinson’s when individuals have occupational or residential exposure to pesticides. This is the first epidemiologic study of Parkinson’s disease that relies on pesticide data that is from a record-based source versus recall-based data relying on individuals’ memory. The second most common neurodegenerative disease affecting more than one million people in the U.S., Parkinson’s disease occurs when nerve cells in the substantia nigra region of the brain are damaged or destroyed and can no longer produce dopamine, a nerve-signaling molecule that helps control muscle movement. The new UCLA study is […]

(Beyond Pesticides, February 24, 2009) NIEHS staff scientist Freya Kamel, Ph.D., Harvard School of Public Health professor Chensheng (Alex) Lu, Ph.D., and Wake Forest University’s Center for Worker Health director Thomas Arcury, Ph.D. will speak as Science and Health panelists at Bridge to an Organic Future: Opportunities for health and the environment, the 27th National Pesticide Forum, April 3-4 in Carrboro, NC. Freya Kamel, Ph.D. Freya Kamel’s research interests focus on environmental determinants of neurologic dysfunction and disease, in particular, neurodegenerative disease. Dr. Kamel and her colleagues at the National Institute for Environmental Health Sciences (NIEHS) of the National Institutes of Health (NIH) examined the relationship of farm work-related exposures to subclinical neurobehavioral deficits in farmworkers. Deficits in neurobehavioral performance reflecting cognitive and psychomotor function related to the duration of work experience were seen in former as well as current farmworkers, and decreased performance was related to chronic exposure even in the absence of a history of pesticide poisoning. Thus, long-term experience of farm work is associated with measurable deficits in cognitive and psychomotor function. Dr. Kamel participated in work on the Agricultural Health Study (AHS), a large cohort study of licensed pesticide applicators and their spouses in Iowa and […]

(Beyond Pesticides, February 23, 2009) Permethrin and lindane metabolites are found in children who use lice shampoos containing the insecticides, according to researchers affiliated with the Centers for Disease Control and Prevention. The study, “Pesticide exposure resulting from treatment of lice infestations in school-aged children in Georgia,” published in the February issue of the journal Environment International, is the first to measure children’s exposure to chemical lice treatments. The researchers collected baseline urine samples from 78 enrolled children between the ages of six to ten years of age. About one-third of those children were diagnosed with head lice and subsequently treated with at least one over-the-counter permethrin lice treatment, a prescription lindane treatment, or both. Within seven days of the insecticide application, urine samples were again collected. The permethrin exposed children had significantly higher urinary pryrethoid metabolite levels in their post-exposure urine samples. Lindane metabolites were also elevated in urine samples after treatment. Interestingly, the study states, “Exposed participants appeared to have higher pre-exposure metabolite levels — likely from multiple treatments before enrollment — than unexposed participants.” Pentachlorophenol, a metabolite of lindane, was significantly higher in the urine of those children who used a lice treatment regardless of whether it […]

(Beyond Pesticides, February 18, 2009) The Environmental Protection Agency (EPA) is accepting through February 23, 2009 public comments on a petition to cancel all registrations for the herbicide 2,4-D and to revoke all of its tolerances. The petition was filed by the Natural Resources Defense Council (NRDC) in November and published by EPA on December 24, 2008. As the most commonly used “home and garden” chemical, millions of U.S. households especially vulnerable children and pets, are exposed to this toxic chemical. Beyond Pesticides fully supports the cancellation of this dangerous pesticide which has been associated with a host of adverse human impacts, such as non-Hodgkin’s lymphoma, endocrine disruption, reproductive and developmental effects, as well as water contamination and toxicity to aquatic organisms. The highly toxic chemical can be replaced by cost-competitive and effective management practices widely used in organic agriculture and lawn care. As long as 2,4-D remains on the market, the public will continue to be exposed to, and suffer the effects of this chemical whose health impacts have long been ignored by EPA. Public health and environmental advocates believe it is time that EPA put science and the health of the public and the environment first and ban […]

(Beyond Pesticides, February 17, 2009) A U.S. District Court Judge has denied a request for remediation in resolving an on-going lawsuit between the victims of the worst industrial disaster in human history in Bhopal, India and Union Carbide, the company responsible for the disaster, according to Reuters, after Union Carbide objected to the victims’ request for remediation. Dow Chemical bought Union Carbide in 2001 and with it, its liabilities for the chemical plant disaster involving the production of methyl isocyanate (MIC), used as an intermediate in the production of the insecticide carbaryl (Sevin). Yet Dow Chemical has refused to clean up the site, provide safe drinking water, compensate the victims, or disclose chemical information to physicians; claiming that the Indian government is responsible for the environmental cleanup. In 1984, Union Carbide was responsible for the 1984 gas leak in Bhopal, India. Forty tons of deadly gas was released. Seven thousand people died in the next few days and 15,000 have died since from illnesses related to the accident. Over 100,000 victims still suffer from illnesses because of this event. In a 1989 settlement, Union Carbide agreed to pay $470 million to victims. However, $330 million still has not been paid […]

(Beyond Pesticides, February 12, 2009) Genetically modified (GM) crops are benefiting biotech food giants instead of the world’s hungry population, which is projected to increase to 1.2 billion by the year 2025 due to the global food crisis, according to a report released yesterday by the Center for Food Safety and Friends of the Earth International. The report, “Who Benefits From GM Crops: Feeding the Biotech Giants Not the World’s Poor,” explains how biotech firms like Monsanto are exploiting the dramatic rise in world grain prices that are responsible for the global food crisis by sharply increasing the prices of GM seeds and chemicals they sell to farmers, even as hundreds of millions go hungry. The findings of the report support a comprehensive United Nations’ assessment of world agriculture in the International Assessment of Agricultural Knowledge, Science and Technology for Development (IAASTD), which in 2008 concluded that GM crops have little potential to alleviate poverty and hunger in the world. IAASTD experts recommended instead low-cost, low-input agroecological farming methods. “U.S. farmers are facing dramatic increases in the price of GM seeds and the chemicals used with them,” said Bill Freese, science policy analyst at the US-based Center for Food Safety […]

(Beyond Pesticides, February 11, 2009) Connecticut lawmakers are taking an interest in the much debated cause of a massive die-off of lobsters that has all but wiped out the state’s 40 million dollar industry, according to the Easton Courier. Fishermen and environmentalists blame the use of the insecticide malathion, a hazardous organophosphate, currently used in community mosquito eradication programs, however the state Department of Environmental Protection (DEP) argues that there is not enough scientific data to lead to the banning of the chemical. The huge die-off of lobsters began in 1999, days after towns in Fairfield County, Westchester County and Long Island, as well as New York City, sprayed malathion to kill mosquitoes carrying the West Nile virus. Also at that time, remnants of hurricane Floyd drenched the state and washed the pesticide into Long Island Sound. The DEP, however, says the storm caused many other factors that led to the mass die-off. However, the lobster population has yet to recover. State lawmakers find DEP’s position on malathion puzzling. Rep. Richard Roy (D-Milford), chair of the House Environment Committee, and Senate Assistant Majority Leader Bob Duff (D-Norwal) are questioning DEP about its efforts to restore the state’s lobster industry while […]

(Beyond Pesticides, February 9, 2009) The U.S. Environmental Protection Agency (EPA) is currently soliciting comments on Monsanto’s second application to extend its experimental use permit for soybeans genetically engineered (GE) with the soil bacterium Bacillus thuringiensis (Bt). This will be the new administration’s first test on how it handles the issues surrounding GE crops. Among a number of concerns regarding GE crops, crops engineered to contain Bt threaten the long-term efficacy of Bt, which is an approved insecticide in organic farming. Monsanto’s permit on these GE soybeans was first granted by EPA in September 2007 and then extended in April 2008. Under the permit, plantings are permitted through July 31, 2009. Monsanto is requesting to extend the experimental program until December 31, 2010 and amend it by conducting tests with up to 0.466 pounds of Bt Cry1Ac protein in soybeans on 1,362 acres, according to the February 4th Federal Register notice. The testing trials will take place in Arkansas, Illinois, Indiana, Kentucky, Maryland, Missouri, North Carolina, Puerto Rico, South Carolina, and Virginia. Following the review of the application and any comments and data received in response to this solicitation, EPA will decide whether to issue or deny the EUP request, […]

(Beyond Pesticides, February 4, 2009) A new test for triclosan, developed by researchers at the U.S. Department of Agriculture’s Agricultural Research Service (ARS), could help to expedite environmental monitoring of this widely used antibacterial chemical which has been found at high concentrations in rivers and other water resources. Triclosan is linked to a range of health and environmental effects, from skin irritation, bacterial resistance and endocrine disruption, to dioxin contamination and adverse impacts on fragile aquatic ecosystems. The new test called “magnetic particle enzyme immunoassay,” can detect triclosan at a concentration of 20 parts per trillion (ppt)-the equivalent of 1 ounce in 31 million tons. The research team at ARS evaluated the test by using it to detect triclosan and its derivative, methyl-triclosan, in river water, tap water and sewage samples from three municipal plants. They were able to detect triclosan below 20 ppt (the detection limit), indicating very low levels of triclosan in the collected samples. ARS chemist, Weilin L. Shelver, at the ARS Animal Metabolism-Agricultural Chemicals Research Unit in Fargo, N.D., developed the new triclosan test in collaboration with Jennifer Church, Lisa Kamp and Fernando Rubio, a research team at Abraxis, Inc., of Warminster, Pa. Ms. Shelver says […]

(Beyond Pesticides, February 3, 2009) A corporate tomato grower faces an unprecedented penalty of more than $931,000 for misusing pesticides and jeopardizing the health and safety of workers in its New Jersey farm fields and packing houses, New Jersey Department of Environmental Protection (DEP) Acting Commissioner Mark N. Mauriello announced January 30, 2009. In its enforcement action, the DEP cites Ag-Mart Produce Inc., headquartered in Cedarville, Cumberland County, with hundreds of violations that include denying state environmental inspectors access to facilities, losing track of a highly toxic insecticide, failing to properly ventilate areas during pesticide use, failing to post important pesticide-safety information for workers, careless recordkeeping and using forbidden mixtures of pesticides. Ag-Mart Produce widely markets its tomatoes under the brand name “Santa Sweets,” and employs 700 people throughout 17 farm locations in New Jersey. Ag-Mart also owns and operates other produce farms in North Carolina, Florida and Mexico. “Ag-Mart has repeatedly shown a stunning disregard of laws and regulations intended to protect the workers who harvest their tomatoes, the people who consume them and New Jersey’s environment,” Commissioner Mauriello said. “Ag-Mart’s pesticide violations are the most serious DEP inspectors have ever uncovered. We have imposed a record-high penalty not […]

(Beyond Pesticides, January 28, 2009) The U.S. Environmental Protection Agency’s (EPA) national sewage sludge survey identifies high concentrations of toxic contaminants with heavy metals, steroids and pharmaceuticals, including the antibacterials, triclocarban and triclosan. Despite the prevalence of these toxic chemicals in the environment and their potential adverse impacts to human health and the environment, EPA maintains that it is not appropriate to speculate on the significance of the results at this time. Under the Clean Water Act (CWA), Section 405(d) stipulates that EPA must identify and regulate toxic pollutants that may be present in biosolids (sewage sludge) at levels of concern for public health and the environment. The survey, “Targeted National Sewage Sludge Survey” (TNSSS), sampled 74 selected waste water treatment plants in 35 states during 2006 to 2007. The survey, like its three predecessors, is conducted to determine which chemicals are present in sewage sludge and develop national estimates of their concentrations in order to assess whether exposures may be occurring and whether concentrations found may be of concern. The agency conducted analysis of sewage sludge samples for 145 compounds, including four anions (nitrite/nitrate, fluoride, water-extractable phosphorus), 28 metals, four polycyclic aromatic hydrocarbons, two semi-volatiles, 11 flame retardants, 72 […]

Transforming Government’s Approach to Regulating Pesticides to Protect Public Health and the Environment is a document drafted by Beyond Pesticides and Pesticide Action Network North America that captures grassroots pesticide priorities for the Obama Administration. While we have already submitted these priorities to the Obama transition team, we ask for your support and suggestions because we will continue to use this document as we begin to work with the new administration. To sign on to the document, follow the link above and include your name, organization/company affiliation (if any), city and state in the comment field. The document identifies what the Obama administration can/should take on under existing authority/statutory responsibility, with a specific focus on the first 100 days. Most of the comments in our document focus on pending regulatory actions and pending petitions before the government, either because of ongoing chemical reviews, pending rulemaking, or petitions. While we incorporate big picture thinking, we are focused on specific actions that the relevant agencies could take now. We plan to meet and communicate with the Obama administration to put these suggested actions in place. Issues covered in the document include, but are not limited to: Promoting organic agriculture; Protecting sensitive species; […]

(Beyond Pesticides, January 26, 2009) University of California at Irvine researchers have discovered that sulfuryl fluoride, an insecticide widely used to fumigate termite-infested homes and buildings, stays in the atmosphere at least 30-40 years and perhaps as long as 100 years and is about 4,000 times more efficient than carbon dioxide at trapping heat, though much less of it exists in the atmosphere. This raises concerns as levels have nearly doubled in just the last six years. Prior studies estimated its atmospheric lifetime at as low as five years, grossly underestimating the global warming potential. “Sulfuryl fluoride has a long enough lifetime in the atmosphere that we cannot just close our eyes,” said Mads Sulbaek Andersen, a postdoctoral researcher in the Rowland-Blake laboratory and lead author of the study. “The level in the atmosphere is rising fast, and it doesn’t seem to disappear very quickly.” Its climate impact in California each year equals that of carbon dioxide emitted from about one million vehicles. About 60 percent of the world’s sulfuryl fluoride use occurs in California. The insecticide is pumped into a tent that covers a termite-infested structure. When the tent is removed, the compound escapes into the atmosphere. Sulfuryl fluoride […]

(Beyond Pesticides, January 16, 2009) The first comprehensive look at toxic contamination throughout the Columbia River Basin has been released by the U.S. Environmental Protection Agency. Issued today, the Columbia River Basin State of the River Report for Toxics compiles currently available data about four widespread contaminants in the Basin and identifies the risks they pose to people, fish, and wildlife. The four contaminants are: * Mercury * Dichlorodiphenyltrichloroethane (DDT) and its breakdown products * Polychlorinated biphenyls (PCBs) * Polybrominated diphenyl ether (PBDE) flame retardants. According to Elin Miller, EPA Regional Administrator in Seattle, a team of more than 20 federal and state agencies, Tribes, local governments and organizations teamed-up to draw this latest portrait of the toxic threats faced by the Columbia River Basin, which drains nearly 260,000 square miles across seven U.S. states and a Canadian province. “This is troubling news,” said EPA’s Miller. “Today’s Report shows that toxics are found throughout the Basin at levels that could harm people, fish, and wildlife. Federal, tribal, state, and local efforts have reduced levels of some toxics such as PCBs and DDTs, but in many areas, they continue to pose an unacceptable risk. Tackling this problem will require a coordinated […]

(Beyond Pesticides, January 14, 2009) Two-headed bass found in the Noosa River are at the center of a controversy surrounding pesticide drift from neighboring farms in Queensland, Australia. The pesticides, endosulfan and carbendazim, have been implicated in the contamination of the river, which has yielded thousands of chronically deformed fish. Experts believe that the mutated fish, which survive only 48 hours after hatching, are the victims of pesticide drift from neighboring macadamia nut farms that routinely use endosulfan and the fungicide, carbendazim. Aquatic health expert and vice-president of the Australian College of Veterinarian Scientists’ Aquatic Animal Health Chapter, Matt Landos, PhD, has been investigating the phenomenon and concludes that there were no other probable causes to explain the fish and larval mortality. Dr. Landos documented evidence and completed a report which was sent to the state’s Department of Primary Industries and Fisheries last year. “The timing between the mist spraying and the affected larvae fits hand in glove,” Dr. Landos said. His report also found that chickens, sheep and horses raised at nearby fish hatcheries are also recording abnormally high levels of fetal deaths and birth defects. Gwen Gilson, who runs a Boreen Point fish hatchery, says she has observed […]

(Beyond Pesticides, January 9, 2009) Environmental Toxicology and Chemistry has published a study (Vol. 27(12):2496—2500) entitled “Effects of Malathion on Embryonic Development and Latent Susceptibility to Trematode Parasites in Ranid Tadpoles.” It shows that malathion used as an agricultural insecticide is responsible for interfering with the normal development of pickerel frog embryos, thus leaving them more susceptible to parasite invasion. Malathion is present in natural water sources that have been exposed to urban and agricultural runoff. This organophosphate pesticide can be applied by planes in mosquito control program, and as esult enters water from the air. Although direct lethal and sublethal effects of chemical contaminants have been documented, latent and long-term effects have been less well documented. Therefore, researchers sought to fill this knowledge gap and found, as suspected, that tadpole survival rates decreased and malformations and susceptibility to parasite encystment rates increased as a result of exposure to malathion concentrations mimicking those found in actual water sources. Tadpoles are being exposed to increasing numbers of parasites in waters that are warming as a result of global climate change, and the researchers who performed this study speculate that, as a consequence, those exposed to malathion will have weakened immune systems […]

(Beyond Pesticides, January 5, 2009) According to a new study published December 2008 in the online edition of Environmental Health Perspectives, hexavalent chromium (or chromium VI) found in the wood preservatives chromated copper arsenate (CCA) and acid copper chromate (ACC), is a human carcinogen following chronic oral exposure. Previous studies have shown that hexavalent chromium compounds can increase the risk of lung cancer via inhalation exposure. Chromium VI is the notorious chemical that caused cancer in the residents of Hinkley, CA and brought to light by the work of Erin Brockovich. The National Toxicology Program (NTP) conducted 2-year drinking water studies of chromium VI (as sodium dichromate dihydrate) in male and female F344/N rats and B6C3F1 mice. Exposure resulted in increased incidences of rare neoplasms of the squamous epithelium that lines the oral cavity (oral mucosa and tongue) in male and female rats, and of the epithelium lining the small intestine in male and female mice. The authors determined that chromium Vi is carcinogenic following administration in drinking water to male and female rats and mice. The International Agency for Research on Cancer (IARC), the U.S. Department of Health and Human Services, and the Environmental Protection Agency (EPA) each have […]

(Beyond Pesticides, December 22, 2008) The U.S. EPA has filed an administrative complaint, seeking a maximum penalty of only $4,550, against a pest control company that sprayed pesticides in a couple’s home, causing the wife to die shortly thereafter. It has been more than three years since the incident took place in Florence, Oregon. Swanson’s Pest Management of Eugene, Oregon sent an employee to a home on June 29, 2005 to apply Conquer Residential Insecticide Concentrate, active ingredient esfenvalerate, and ULD BP-100 Contact Insecticide, active ingredient pyrethrin. The couple returned to their home two and a half hours later and immediately fell to the ground due to the fumes. Paramedics were called in and they too experienced respiratory distress or became ill when they entered the treated home. According to The Oregonian, Florence Kolbeck was 76 years old and died of cardiac arrest as a result of the exposure. Her husband, Fred, was hospitalized for respiratory distress. The complaint was filed following a review of Swanson’s use of the two pesticides, finding that the company failed to properly ventilate the home prior to the occupants re-entering, and improperly applied Conquer as a “space spray” at nearly three times the allowable […]

(Beyond Pesticides, December 19, 2008) In resopnse to an Environmental Protection Agency (EPA) published final Reregistration Eligibility Decision (RED) document for triclosan (October 29, 2008), groups are citing a serious lack of health and environmental protection and the agency’s failure to meet its statutory duty. Formal comments will be submitted to the agency during a comment period that ends at the end of December 2008. Groups have been invited to sign a joint statement. Triclosan is a synthetic, broad-spectrum antimicrobial agent that in recent years has exploded onto the consumer market in a wide variety of antibacterial soaps, deodorants, toothpastes, cosmetics, fabrics, plastics, and other products. Studies link triclosan to a range of health and environmental effects, from skin irritation, allergy susceptibility, bacterial and compounded antibiotic resistant, and dioxin contamination to destruction of fragile aquatic ecosystems. Many of Beyond Pesticides comments that were submitted on July 7, 2008 were considered and amendments were made to the risk assessment. However, despite many lingering issues related to triclosan continued threat to human and environmental health, the agency concluded that triclosan was eligible for reregistration. This means that the continued and expanding use of this chlorinated, bioaccumulative pesticide, with the ability to produce […]

(Beyond Pesticides, December 18, 2008) The New Zealand’s Environmental Risk Management Authority (ERMA) has announced it will ban the controversial organochlorine pesticide endosulfan, effective January 16, 2009. Endosulfan, already banned in numerous countries including all the European Union countries, is an insecticide used on a wide range of fruits and vegetables and also on athletic fields in New Zealand. Illegal residues have been found in beef destined for South Korea, resulting in enormous costs for New Zealand exporters. Use of endosulfan for agriculture continues in the U.S., despite causing severe health and environmental problems. A coalition of groups, including the Pesticide Action Network Aotearoa New Zealand (PAN ANZ), Soil and Health Association and Safe Food Campaign, have long campaigned for the banning of endosulfan. Earlier this year, the three organizations carried out a number of residue tests on produce to draw attention to the extent of endosulfan residues, especially in tomatoes. “We are delighted that ERMA has overturned its earlier ”˜proposed’ decision to keep using this pesticide,” stated Meriel Watts, Ph.D., co-coordinator of PAN ANZ. “It would have been deeply embarrassing for New Zealand to continue its use when the pesticide has entered the process for a global ban under […]

(Beyond Pesticides, December 16, 2008) According to a new study, published in the December 2008 issue of Environmental Health Perspectives by researchers at Columbia University’s Mailman School of Public Health, pregnant women continue to be exposed to pesticides in the home. In fact, 75% of the sampled homes of pregnant women in inner-city New York are contaminated with piperonyl butoxide (PBO), a pesticide synergist linked to cancer and other health problems. Following the Environmental Protection Agency’s phase-out agreements with the manufacturers of organophosphate insecticides chlorpyrifos and diazinon in 2000 and 2001, the Columbia University researchers sought to determine the impact of the new regulations on pest infestation levels, pesticide use, and pesticides measured in indoor air samples. They enrolled 511 pregnant women from inner-city New York between 2000 and 2006. Permethrin, a pyrethroid insecticide; PBO, a pyrethroid synergist; chlorpyrifos; and diazinon were measured in 48-hr prenatal personal air samples. Data on pest infestation and pesticide use were collected via questionnaire. 88% of women report using pesticides during pregnancy and 55% report using higher-exposure pesticide applications (spray cans, pest bombs and/or professional pesticide applicators). Self-reported pest sightings and use of higher-exposure applications increased significantly after the regulations were implemented. PBO, cis-, […]