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Daily News Blog

Archive for the 'Diabetes' Category


12
Nov

Researchers Strengthen Link Between Diabetes and Pesticide Exposure

(Beyond Pesticides, November 11, 2008) Researchers at the Duke University School of Medicine have linked organophosphate pesticides to the epidemics of obesity and type 2 diabetes. The researchers specifically link neonatal low-dose parathion exposure in rats to disruption of glucose and fat homeostasis. The study, “Exposure of Neonatal Rats to Parathion Elicits Sex-Selective Reprogramming of Metabolism and Alters the Response to a High-Fat Diet in Adulthood,” was published in the November 2008 issue of Environmental Health Perspectives. It follows research by the National Institutes of Health (NIH) that links pesticide exposure to type 2 diabetes using epidemiological data from the Agricultural Health Study. Although most studies of organophosphates focus on their neurotoxicity, there is increasing evidence that these agents may also have a lasting impact on metabolic function. According to authors, obesity and consequent type II diabetes are rising at epidemic rates in the U.S. and many other countries around the world. Two of three U.S. adults are now classified as overweight. There are epidemiologic links between pesticide exposure and diabetes, and the same subpopulations that have the highest rates of obesity””inner-city, low-socioeconomic-status, agricultural populations””are also those that have greater exposure to organophosphates and other pesticides. The researchers chose parathion […]

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08
Sep

Arsenic Exposure Linked to Diabetes

(Beyond Pesticides, September 8, 2008) Inorganic arsenic may increase the risk of developing type 2 diabetes, according to a study published in the Journal of the American Medical Association by researchers at the Johns Hopkins Bloomberg School of Public Health. Common sources of inorganic arsenic exposure include dietary exposure, drinking water pollution, and contamination associated with arsenic wood preservatives such as sawdust, smoke, direct contact, and hazardous waste sites. The study found that individuals with diabetes have higher levels of arsenic in the urine compared to individuals without diabetes. Researchers examined randomly selected urine samples taken from 788 U.S. adults 20 years or older that participated in a 2003-2004 National Health and Nutrition Examination Survey. The results were adjusted for diabetes risk factors, including body mass index and for organic arsenic compounds found in seafood. “Our findings suggest that low levels of exposure to inorganic arsenic may play a role in diabetes,” said Ana Navas-Acien, MD, PhD, lead author of the study and assistant professor with the Bloomberg School’s Department of Environmental Health Sciences. “While prospective studies are needed to establish whether this association is causal, these findings add to the existing concerns about the long-term health consequences of low […]

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06
Jun

Study Shows Increased Diabetes Risk from Pesticide Exposure

(Beyond Pesticides, June 6, 2008) A recent study by the National Institutes of Health (NIH), including the National Institute of Environmental Health Sciences (NIEHS) and the National Cancer Institute (NCI), finds pesticide applicators with regular exposure to pesticides to be at a greater risk of type-2 diabetes. Published in the American Journal of Epidemiology (DOI: 10.1093/aje/kwn028), the study shows specific pesticides produce between a 20 and 200 percent increase in risk. Researchers looked at data from 31,787 pesticide applicators in North Carolina and Iowa over a period of five years. In that period, 1,171, or 3.7 percent, had developed diabetes, particularly for applicators in the highest category of lifetime days of use of any pesticide. “The results suggest that pesticides may be a contributing factor for diabetes along with known risk factors such as diabetes, lack of exercise and having a family history of diabetes,” said Dale Sandler, PhD, chief of the Epidemiology Branch of NIEHS. “Although the amount of diabetes explained by pesticides is small, these new findings may extend beyond the pesticide applicators in the study.” Freya Kamel, PhD, of NIEHS noted that “all of the seven pesticides” associated with an increased risk of type 2 diabetes are […]

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29
Jan

Scientists Say Pesticides and Other Pollutants May Be Linked to Diabetes

(Beyond Pesticides, January 29, 2008) University of Cambridge scientists say there may be a link between persistent organic pollutants (POPs), including pesticides, and Type 2 Diabetes. The Cambridge scientists are advocating additional research into the little understood links between environmental pollution and adult onset diabetes. In the most recent edition of the journal Lancet, Oliver Jones, Ph.D., and Julian Griffin, Ph.D., highlight the need to research the possible link between persistent organic pollutants (POPs, a group which includes many pesticides) and insulin resistance, which can lead to adult onset diabetes. In their commentary, Dr. Jones and Dr. Griffin cite peer reviewed research including that of D. Lee, et al, which demonstrated a very strong relationship between the levels of POPs in blood, particularly organochlorine compounds, and the risk of type 2 diabetes. “Of course correlation does not automatically imply causation,” says Dr. Jones. “But if there is indeed a link, the health implications could be tremendous. At present there is very limited information. Research into adult onset diabetes currently focuses on genetics and obesity; there has been almost no consideration for the possible influence of environmental factors such as pollution.” Interestingly, in the Lee study an association between obesity and […]

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