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Daily News Blog

Archive for the 'metabolic syndrome' Category


27
Jun

Biosolid Biohazard: EPA Sued for Failing to Protect Farmers and Public from PFAS-Contaminated Biosolids

(Beyond Pesticides, June 27, 2024) Earlier this month, Public Employees for Environmental Responsibility (PEER) filed a lawsuit against the U.S. Environmental Protection Agency (EPA) on behalf of a group of ranchers and farmers in Texas harmed by biosolids contaminated with per- and polyfluoroalkyl substances (PFAS). The plaintiffs charge that their health and livelihoods were severely damaged due to contaminated biosolids leaching from neighboring properties onto their land. Despite EPA’s responsibility under the Clean Water Act (Section 405(d) and 40 CFR Part 503) to identify toxic pollutants in biosolids and regulate them to protect human health and the environment, the agency has not effectively addressed the dangers posed by PFAS in biosolid fertilizers. EPA’s failure has dramatic impacts on farmers as well as the public, who are eating or drinking PFAS-contaminated crops, dairy milk, beef, or other meat products. The shortcomings of federal regulations underscore the urgent need for a shift in how federal and state agencies approach these issues, prioritizing precaution to prevent future harm. The persistence of these legacy or “forever” chemicals in the environment illustrates the severe consequences of a historically lax regulatory framework in the U.S.  The National Association of State Departments of Agriculture (NASDA) has identified […]

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15
May

Pesticide Use Again Linked to Inflammatory Bowel Disease, This Time Among Applicators and Their Spouses

(Beyond Pesticides, May 15, 2024) A study published recently in the journal Environmental Research finds a significant correlation between exposure to certain pesticides and an elevated risk of inflammatory bowel disease (IBD), a chronic autoimmune condition of the gastrointestinal tract. The study, adding to the body of science on this subject, evaluates self-reported data from licensed pesticide applicators and their spouses exposed to pesticides for over 20 years. In addition, while some of the chemicals found to be most closely associated with incidents of IBD have been banned from use, they are “forever” chemicals that persist in the environment for generations. These findings demonstrate once again the failings of the current regulatory process to identify hazards before they are put into the environment. The study found evidence that exposure to several organochlorine insecticides (dieldrin, DDT, and toxaphene), as well as organophosphate insecticides (parathion, terbufos, and phorate) and herbicides (2,4,5-T, 2,4,5-TP, and metolachlor), is associated with elevated IBD risk. IBD is a generic term for diseases that result in chronic inflammation of the gastrointestinal tract, such as Crohn’s disease and ulcerative colitis. It is estimated that 6.8 million patients globally suffered from IBD in 2017. IBD may result from an imbalance […]

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17
Apr

“Forever Chemical” PFAS Drinking Water Rules Issued, Urgency to Shift from Petrochemicals Pesticides

(Beyond Pesticides, April 17, 2024) With headlines drawing public attention to the contamination of drinking water after years of federal government neglect, the U.S. Environmental Protection Agency (EPA) announced on April 10 new standards to reduce public exposure to PFAS, or per- and polyfluoroalkyl substances, commonly referred to as “forever chemicals” because of their persistence. EPA has finalized a National Primary Drinking Water Regulation (NPDWR) for six PFAS, including PFOA and PFOS, which EPA has recognized have no safe level of exposure, regulating new chemicals for the first time since the 1996 amendments to the Safe Drinking Water Act (SDWA). PFAS persistence and bioaccumulation in humans, wildlife, and the environment is due to the strength of a resulting fluorine–carbon atom bond. PFAS contamination of drinking water, surface and groundwater, waterways, soils, and the food supply—among other resources—is ubiquitous worldwide. PFAS is used in everyday products, including cookware, clothes, carpets, as an anti-sticking and anti-stain agent, in plastics, machinery, and as a pesticide. The action was welcomed by environmentalists and public health advocates as an important step but left many concerned that any level of exposure to these chemicals is unacceptable and critical of EPA’s ongoing failure to act despite years […]

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04
Mar

Take Action: Federal Food Program Asked to Stop Feeding Children Pesticides that Contribute to Obesity

(Beyond Pesticides, March 4, 2024) With 14.7 million children and adolescents in the U.S. recognized as obese by the Centers for Disease Control and Prevention (CDC) and the established connection with endocrine disrupting contaminants, including many pesticides, Beyond Pesticides is calling on federal food assistance programs to go organic. The problem of childhood obesity is higher in people of color and, as a result, is an environmental justice issue. According to CDC, the prevalence of childhood obesity is “26.2% among Hispanic children, 24.8% among non-Hispanic Black children, 16.6% among non-Hispanic White children, and 9.0% among non-Hispanic Asian children.” While childhood obesity is recognized as a serious problem, the National School Lunch Program of the U.S. Department of Agriculture (USDA)—although improved by the Healthy, Hunger-Free Kids Act of 2010—still provides lunches laced with obesogenic pesticides. To take meaningful steps against childhood obesity, school lunches must be organic. The program served 4.9 billion meals in fiscal year 2022 in over 100,000 public and nonprofit schools, grades Pre-Kindergarten-12. Contrary to popular opinion, the blame for the obesity epidemic cannot be attributed solely to diet and exercise broadly, but relates directly to pesticide and toxic chemical exposures, including residues in food, that may lead […]

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01
Mar

Literature Review on Obesogens Highlights the Long-Term Metabolic Impacts of Pesticide Exposure

(Beyond Pesticides, March 1, 2024) A comprehensive research review published in Environment & Health analyzes existing research demonstrating the link between an increase in obesity and the proliferation of synthetic chemicals that “interfere with lipid metabolism.” The study documents over 50 obesogens with high-level human exposure rates, including per- and poly-fluoroalkyl substances (PFASs), phthalates (PAEs), and polybrominated diphenyl ethers (PBDEs), that can lead to lipid metabolism disruption including health impacts on the liver and insulin resistance, among other metabolic conditions such as diabetes, hypertension, cardiovascular disease, and dyslipidemia. Authors in this study highlight the scientific research community’s focus on adipose tissue and the liver, and a need to further explore effects on cardiovascular and kidney health. This anthology of research demonstrates the complexity of the threats associated with toxic pesticides, the severe limitations of their regulatory review, and the failure to consider organic practice and product alternatives that eliminate their use. Environmental obesogens are chemicals that are proven to have a health impact on metabolic systems relating to obesity. This review evaluates literature, going back to the 2006 obesogen hypothesis, on the metabolic impacts of environmental obesogens, including epidemiologic data, in vitro studies, and bioassays. Researchers scanned Web of Science, […]

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27
Feb

Pesticide Exposure Linked to Obesity, Type 2 Diabetes, and Metabolic Disease in Seniors

(Beyond Pesticides, February 27, 2024) Popular culture and official policy continue to ignore a blatant source of the rise in obesity: chemical exposures, including pesticides. A study, “Associations of chronic exposure to a mixture of pesticides and type 2 diabetes mellitus in a Chinese elderly population,” contributes to the now-massive trove of evidence linking pesticides to diseases and shows that by the time people reach retirement age they are suffering from a heavy burden of contamination that raises their risk of complex disease. Since the 1960s, obesity in both adults and children has nearly tripled. More than half of U.S. adults were either obese or severely obese by 2018, according to data from the National Health and Nutrition Examination Study. The 55-year trend line is decidedly upward. More women than men are obese, and black women suffer the most, but men are racing to catch up. Between 1999 and 2018, Mexican American men shot up from the lowest percentage of obesity to nearly the highest. Obesity is a milestone on the road to Type 2 diabetes, heart disease, high blood pressure, kidney failure, joint replacement, and more. The causes of obesity are severely misunderstood. Most people believe that discipline and […]

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27
Sep

Metabolic Diseases, Including Diabetes and Obesity, Driven by Pesticide Exposure

(Beyond Pesticides, September 27, 2023) A study published in Pesticide Biochemistry and Physiology finds organophosphate (OP), organochlorine (OC), and pyrethroid (PYR) pesticides have links to insulin resistance (IR) associated with metabolic disorders like diabetes, obesity, chronic kidney disease (CKD), and hypertension. Metabolic disorders are among the leading causes of morbidity and mortality, with over 11 percent (>37 million) of individuals in the U.S. having diabetes, and cases are growing by millions annually. Additionally, there is a rise in metabolic disorders among young people. Studies even find low levels of pesticide exposure during pregnancy or childhood cause adverse health effects, including metabolic disorders tied to gut microbiome disruption (dysbiosis). With increasing rates of diabetes and obesity, the two most prominent metabolic diseases in the study, cases among the global population, studies like these highlight the importance of evaluating how chemical contaminants deregulate normal bodily function through metabolic changes.  To investigate the association between pesticide exposure and insulin-related metabolic disorders in humans, researchers searched the PubMed database for articles, performing a systematic review. The study notes, “IR is defined as a pathological state in which a higher-than-normal level of insulin is required to produce the optimal response in cells.” The search generated 4,051 articles related to the topic. However, after excluding duplicates and […]

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07
Mar

Glyphosate Exposure Associated with Liver and Metabolic Disorders in Children, Young Adults

(Beyond Pesticides, March 7, 2023) Exposure to glyphosate (Roundup) and its breakdown products is associated with an increased risk of liver and metabolic disorders in children and young adults, according to research published in Environmental Health Perspectives earlier this month. While glyphosate has developed a well-deserved reputation as a carcinogen, research is finding that cancer is one of a myriad of chronic diseases associated with the notorious chemical. As this body of literature grows, growing awareness by the public is increasing pressure on the U.S. Environmental Protection Agency to cancel its allowed uses. Researchers began their investigation concerned about the rise of liver disorders and metabolic syndrome among young people. This trend has been pronounced among populations of color. The worrying increase has led many to consider synthetic chemical exposure as a contributing factor, as lack of diet and exercise is unlikely to account for the entirety of the increase. To better understand these impacts, researchers enrolled existing participants in the CHAMACOS (Center for the Health Assessment of Mothers and Children of Salinas) study, a long running cohort of mothers and their children born between the years 2000 and 2002 in the Salinas Valley of California. Enrolled participants consistent mostly […]

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