17
Apr
(Beyond Pesticides, April 17, 2024) With headlines drawing public attention to the contamination of drinking water after years of federal government neglect, the U.S. Environmental Protection Agency (EPA) announced on April 10 new standards to reduce public exposure to PFAS, or per- and polyfluoroalkyl substances, commonly referred to as “forever chemicals” because of their persistence. EPA has finalized a National Primary Drinking Water Regulation (NPDWR) for six PFAS, including PFOA and PFOS, which EPA has recognized have no safe level of exposure, regulating new chemicals for the first time since the 1996 amendments to the Safe Drinking Water Act (SDWA). PFAS persistence and bioaccumulation in humans, wildlife, and the environment is due to the strength of a resulting fluorine–carbon atom bond. PFAS contamination of drinking water, surface and groundwater, waterways, soils, and the food supply—among other resources—is ubiquitous worldwide. PFAS is used in everyday products, including cookware, clothes, carpets, as an anti-sticking and anti-stain agent, in plastics, machinery, and as a pesticide. The action was welcomed by environmentalists and public health advocates as an important step but left many concerned that any level of exposure to these chemicals is unacceptable and critical of EPA’s ongoing failure to act despite years […]
Posted in Agriculture, Alternatives/Organics, Announcements, Arkansas, Biosolids, Birth defects, Brain Effects, California, Cancer, Cardiovascular Disease, Chemicals, Connecticut, contamination, Developmental Disorders, Disease/Health Effects, Drinking Water, Endocrine Disruption, Environmental Protection Agency (EPA), Farmworkers, Fertilizer, Groundwater, Hawaii, Herbicides, Illinois, Infertility, Inflammatory bowel disease (IBD), Inhance Technologies, Lawns/Landscapes, Liver Damage, Maine, Maryland, Massachusetts, Metabolic Disorders, metabolic syndrome, metabolic syndrome, Michigan, Minnesota, Motor Development Effects, Motor neuron disease, National Organic Standards Board/National Organic Program, New Hampshire, New Jersey, New Mexico, New York, North Carolina, NOSB National Organic Standards Board, Obesity, Ohio, Oregon, Parks for a Sustainable Future, Pennsylvania, Pesticide Mixtures, Pesticide Regulation, PFAS, Plastic, Reproductive Health, Rhode Island, Sewage Sludge, soil health, Synthetic Fertilizer, Take Action, Thyroid Disease, U.S. Geological Survey, Uncategorized, Vermont, Washington, Water, Water Regulation, Wisconsin | No Comments »
04
Jan
(Beyond Pesticides, January 4, 2024) A review published in the Journal of Neurosciences in Rural Practice finds an association between farmers’ pesticide exposure and cognitive impairment. Specifically, farmers suffer from attention deficit, lack of information processing, non-comprehension of verbal cues, slow processing speed, memory loss, sluggishness, speech difficulties, and impaired motor function. Additionally, the risk of adverse effects from exposure increases with time spent around pesticides, like in other occupational (work-related) settings. Although pesticide exposure may not be the only factor involved in cognitive impairment, exposure can work synergistically (together) with other factors, triggering neurotoxicity. Pesticides play various roles in causing or exacerbating adverse health outcomes like neurotoxic effects and chemical damage to the brain. Numerous pesticides impair neurological function, especially for chronically exposed individuals (e.g., farmworkers) or during critical windows of vulnerability and development (e.g., childhood, pregnancy). Mounting evidence over the past years shows that chronic exposure to sublethal (low) levels of pesticides adversely affects the central nervous system (CNS) and neural receptors, such as connections between nerves, the brain, enzymes, and DNA. Specifically, researchers identify agricultural chemical exposure as a cause of many adverse CNS impacts and neurological diseases, including Alzheimer’s, amyotrophic lateral sclerosis (ALS), and Parkinson’s disease. The researchers reviewed scientific articles published in […]
Posted in behavioral and cognitive effects, Brain Effects, Chemicals, Developmental Disorders, Motor neuron disease, Nervous System Effects, Occupational Health, organophosphate, synergistic effects | No Comments »
12
Jan
(Beyond Pesticides, January 12, 2023) Exposure to certain pesticides among individuals diagnosed with Parkinson’s disease (PD) can increase the risk of symptom progression. According to a study published in Science of the Total Environment, nearly 20 percent of pesticides associated with the onset of PD also increase the risk of faster decline in motor and non-motor function. Several studies find exposure to chemical toxicants, like pesticides, has neurotoxic effects or exacerbates preexisting chemical damage to the nervous system. Past studies suggest neurological damage from oxidative stress, cell dysfunction, and synapse impairment, among others, can increase the incidence of PD following pesticide exposure. Despite the association between PD onset via pesticide exposure patterns, few epidemiologic studies examine the influence pesticides have on worsening motor and non-motor symptoms in PD. Parkinson’s disease is the second most common neurodegenerative disease, with at least one million Americans living with PD and about 50,000 new diagnoses annually. The disease affects 50 percent more men than women, and individuals with PD have a variety of symptoms, including loss of muscle control and trembling, anxiety and depression, constipation and urinary difficulties, dementia, and sleep disturbances. Over time, symptoms intensify, but there is no current cure for this fatal disease. While […]
Posted in copper sulfate, Dicamba, MCPA, Methamidophos, Motor neuron disease, MSMA, Nervous System Effects, Parkinson's, Propargite | 1 Comment »
04
Aug
(Beyond Pesticides, August 4, 2022) An Arizona State University (ASU) study shows that the popular herbicide glyphosate can infiltrate the brain through the blood (blood-brain barrier), increasing neurological disease risk. The blood-brain barrier filters various molecules entering the brain from the circulatory system. However, the permeation of glyphosate molecules elevates the expression of TNFα and the accumulation of soluble beta-amyloid (Aβ) proteins in the brain and has associations with immune, inflammatory, and neurodegenerative diseases like Alzheimer’s disease (AD). More than 6 million people in the U.S. are living with Alzheimer’s, and cases are expected to double by 2050. Although Alzheimer’s research has focused heavily on finding genetic causes of the disease, fewer than half of cases are genetic. Thus, researchers are now evaluating how environmental contaminants may increase disease risk. Over 300 environmental contaminants and their byproducts, including pesticides, are chemicals commonly present in human blood and urine samples and can increase neurotoxicity risk when crossing the brain barrier. Therefore, studies like this highlight the importance of understanding how chemical accumulation in the body can impact long-term health and disease prognosis. The study notes, “Brain glyphosate correlates with increased TNFα levels, suggesting that exposure to this herbicide may trigger neuroinflammation in the brain, which may […]
Posted in Alzheimers's, Brain Effects, Glyphosate, Motor neuron disease, Nervous System Effects | No Comments »
08
Apr
(Beyond Pesticides, April 8, 2008) A team of University of Michigan scientists discover interactions between genes and organophosphate exposure cause some forms of motor neuron disease (MND). The study, which appears in the March issue of the American Journal of Human Genetics, shows the mutations in one key gene (neuropathy target esterase, or NTE) that causes a previously unknown type of inherited MND. The scientists also find the mutations caused changes in a protein already known to be involved when people develop neurologic disorders as a result of exposure to toxic organophosphate chemicals commonly used in solvents and insecticides and also as “nerve gas” agents. Motor neuron disease is a rare, devastating illness in which nerve cells that carry brain signals to muscles gradually deteriorate. One form of it is Lou Gehrig’s disease or ALS (amyotrophic lateral sclerosis). For most MND patients, the cause is unknown. Figuring out why these people develop the disease, which causes muscles to weaken, atrophy and cease to function, is an important step in developing therapies to treat or prevent motor neuron disease. Motor neuron disease affects five per 100,000 people. “Our findings support the possibility that toxic organophosphates contribute to motor neuron disease in […]
Posted in Motor neuron disease | No Comments »
