(Beyond Pesticides, January 21, 2025) When the American Cancer Society (ACS) published its annual report last week, it pointed to a rising incidence of cancer in younger women and highlighted disparities by race and ethnicity that are especially timely with the commemoration of Dr. Martin Luther King, Jr. In its report, “Cancer Mortality Continues to Drop Despite Rising Incidence in Women; Rates of New Diagnoses Under 65 Higher in Women Than Men,” ACS writes: “Disparities in cancer occurrence and outcomes are often the result of socioeconomic deprivation as a consequence of structural racism, which limits opportunities for education and other mechanisms of upward mobility. For example, the historical practice of mortgage lending discrimination known as redlining is associated with later stage cancer diagnosis, lower likelihood of receiving recommended treatment, and higher cancer mortality. Inequalities in wealth lead to differences in the prevalence of risk factor exposures as well as access to high-quality cancer prevention, early detection, and treatment. Even beyond higher prevalence of common risk factors like smoking and obesity, exposure to carcinogenic air emissions is up to 50% higher among people experiencing poverty, regardless of race or ethnicity. In 2022, 25% of AIAN [American Indian and Alaska Native] people lived below the federal […]

(Beyond Pesticides, January 17-20, 2025) Martin Luther King Day recognizes the achievements of a remarkable civil rights leader while asking the nation to assess what more the country must do to ensure equality and environmental justice, as well as protection for those who suffer disproportionately from toxic chemical exposure. Advocates and disproportionately affected communities acknowledge the historic nature of the Biden Administration’s commitment to elevating environmental justice in the decision-making of the U.S. Environmental Protection Agency (EPA). However, according to Willy Blackmore, writer for Minnesota Spokesman-Recorder (“the oldest Black-owned newspaper in the state of Minnesota and one of the longest-standing, family-owned newspapers in the country”), “[T]he more systemic change that [Administrator] Regan’s EPA tried to bring about was stonewalled by legal challenges that threatened to undermine the agency’s strongest tool for righting environmental injustices.” Black communities across the nation face disproportionate impacts to petrochemical infrastructure and toxic chemicals, including pesticides and fertilizers. A 2021 study published in BMC Public Health found that biomarkers for 12 dangerous pesticides tracked over the past 20 years were found in the blood and urine of Black participants at average levels up to five times those in White participants. A University of Michigan study found […]

(Beyond Pesticides, January 16, 2025) In Ecotoxicology and Environmental Safety, researchers highlight a multitude of studies on endocrine disrupting chemicals (EDCs) and endocrine disrupting pesticides (EDPs) showing epigenetic effects from exposure. These EDCs imitate the action of endocrine hormones and lead to gene damage and multigenerational adverse effects to health. “These chemicals can interfere with the normal functioning of target tissues by altering their response to hormonal signals, thereby affecting various physiological processes including reproduction, development, the nervous system, the immune system, and even the process of carcinogenesis [causing cancer],” according to the authors from Hebei Agricultural University and Chinese Academy of Agricultural Sciences.   In causing epigenetic modifications, the authors describe that EDCs can create changes “at the nuclear and mitochondrial DNA (nDNA and mtDNA) or RNA levels, without changing the underlying DNA sequence. These alterations modify the structure or conformation of DNA, influencing gene expression and, consequently, cellular function.” They continue, “The mechanisms of epigenetics include changes in DNA methylation, chromatin modifications and the involvement of certain noncoding RNAs.” In reviewing over 80 studies on EDCs, predominantly fluorinated compounds such as per- and polyfluoroalkyl substances (PFAS), the researchers provide a summary of linkages between pesticide exposure and the […]

(Beyond Pesticides, January 15, 2025) There is robust scientific literature that unpacks the adverse human health effects of pesticide exposure, however immunological impacts do not receive adequate attention in regulatory review processes, according to an in-depth literature review. In a piece published in Frontiers in Immunology (2024) critiquing recent peer-reviewed scientific studies, as well as unpublished research produced by the Institute of Biology and Experimental Medicine in partnership with the National Scientific and Technical Research Council in Argentina, researchers assess immune system effects of pesticide exposure, which creates the conditions for deadly health conditions including various forms of cancer. The focus of this study, according to the authors, is “to critically review fundamental aspects of toxicological studies conducted on PPPs [Plant Protection Products] to provide a clearer understanding of the risks associated with exposure to these compounds on human health.” PPPs are pesticide products that contain more than one active ingredient, and can include synergistic ingredients that supercharge them alongside inert ingredients that pesticide companies are not legally required to disclose under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), but are often manipulated biologically and chemically active. Most studies analyze the toxicological impacts of active ingredients in isolation rather […]

(Beyond Pesticides, January 14, 2025) Women with occupational pesticide exposure have elevated rates of breast cancer, according to a study in Immunopharmacology and Immunotoxicology. Based on an analysis of clinicopathological data from 188 affected women, the study authors demonstrate “that occupational exposure to pesticides modifies the clinical presentation of disease in breast cancer patients, depending on their age at disease onset, affecting cytokine production, especially in those exhibiting early age at diagnosis.”   “Breast cancer (BC) is the most common malignant neoplasm affecting women worldwide and the second leading cause of cancer-related death in this population,” the researchers report. They continue: “Aging is the primary risk factor associated with breast cancer development and mortality, resulting in a cumulative lifetime risk of 1 in 8 women developing the disease. Disease onset significantly impacts patient prognosis. While most cases are of late onset and occur in women over 50 years of age, early-onset BC is prevalent in certain populations and is associated with a poor prognosis and aggressive tumor behavior.”  Data was collected and analyzed from May 2015 to December 2022, with the study population in Brazil spanning “27 municipalities in the southwest of Paraná, a region characterized by extensive pesticide use, predominantly […]

(Beyond Pesticides, January 9, 2025) In a Frontiers in Public Health review article, researchers report on the wide body of science connecting adverse effects to female reproductive system, such as infertility, with exposure to endocrine-disrupting chemicals (EDCs). The authors call these effects a significant concern for public health, as there has been growing evidence of EDCs with risk factors for decreased fertility.   Infertility “affects a substantial proportion of the world’s population with approximately one in six people affected,” the researchers note. They continue: “Over the last 70 years, global fertility has been constantly in decline due to behavioral and societal changes… [E]merging evidence has shown that infertility incidence is linked to exposure to environmental factors such as tobacco, alcohol, and a wide range of endocrine-disrupting chemicals (EDCs) including pesticides (chlorpyrifos, glyphosate, dichlorodiphenyltrichloroethane [DDT] and methoxychlor), phthalates, polychlorinated biphenyls (PCB), dioxins, and bisphenols.”  In this review, over 100 studies are summarized to showcase the link between EDC exposure and reproductive effects in women, including infertility and related diseases such as endometriosis, premature ovarian insufficiency (POI), and endocrine axis dysregulation. The studies included investigating the “mechanisms by which EDCs cause ovarian aging, folliculogenesis, decrease of oocyte quality, ovulation disorders, development and receptivity […]

(Beyond Pesticides, December 19, 2024) As The New York Times reported last month, the government in South Africa declared a national emergency—23 children died and nearly 900 people were sickened from pesticide poisoning in Johannesburg’s Soweto township. The illnesses and fatalities have been traced to small amounts of highly neurotoxic pesticides, including the insecticides terbufos and aldicarb, found in local food items. These chemicals, described by South African President Cyril Ramaphosa as “street pesticides,” are being increasingly used (legally and illegally) for pest infestations in the townships and informal settlements of South Africa’s poorest communities, where poverty and inadequate waste collection exacerbates the pest management challenges. Without formal electricity, running water, or municipal garbage collection, many residents rely on highly toxic pesticides for pest infestations in their homes and makeshift markets, resulting in food inadvertently being contaminated with pesticides.  The announcement highlights the dangers of allowing these highly toxic agricultural chemicals to be used in farming, with tragic consequences for vulnerable communities when they are diverted for use in urban settings. This tragic situation also draws attention to the elevated threat that pesticides pose when stringent enforcement mechanisms are not in place to ensure compliance with pesticide restrictions, even with […]

(Beyond Pesticides, December 17, 2024) A systematic review of studies on pesticides as endocrine-disrupting chemicals (EDCs) on body weight, published in Biomedicines, evaluates 36 clinical and preclinical studies and links their agricultural use to obesity. The authors, with the lead researchers from the School of Medicine and Health Sciences at Catholic University of Valencia San Vincente, Valencia, Spain, assess studies on a range of pesticides, including organophosphates, pyrethroids, neonicotinoids, and others. In addition to concluding that the EDCs promote obesity, they report that the chemicals cause “other anthropometric changes by altering lipid and glucose metabolism, modifying genes, or altering hormone levels such as leptin.” Endocrine disruption and obesity are public health concerns, and there is a wide body of science linking pesticide exposure to these effects (see more here). “Obesity is considered to be a worldwide pandemic that leads to an increase in medical costs and thus becomes a public health problem,” the researchers share. They continue, “[Obesity] is also associated with the increased production of environmental chemicals, also called environmental obesogens, used mainly in agriculture, as disease vector control, helping to prevent harmful effects caused by fungi, bacteria, or even pests, using pesticides, insecticides, and herbicides, or endocrine disruptors […]

(Beyond Pesticides, December 16, 2024) The fact that three-quarters of all U.S. fruits and nuts and one-third of all U.S. vegetables are grown in California means that all U.S. food eaters have a stake in how food is grown there. California is proposing the continued use of the fumigant 1,3-dichloropropene (1,3-D, also known as Telone), which can cause deadly effects to farmworkers and endocrine disrupting effects to communities of people exposed through nontarget chemical drift from farmland. So, it is with deep concern that Beyond Pesticides is urging the state of California, where the chemical is undergoing review, to ban the toxicant. Endocrine disruption, an adverse effect for which the U.S. Environmental Protection Agency (EPA) has never completed a pesticide testing protocol, adversely affects the functioning of glands and hormones and is linked to major life-threatening diseases in most organ systems in the body—contributing to attention deficit hyperactivity disorder (ADHD), Parkinson’s, Alzheimer’s, diabetes, cardiovascular disease, obesity, early puberty, infertility and other reproductive disorders, and childhood and adult cancers. In a recently released draft regulation, the California Department of Pesticide Regulation (CDPR) will allow highly elevated exposure to 1,3-D, ignoring the scientific literature and advice of the state’s own toxicologists at […]

(Beyond Pesticides, December 12, 2024) A literature review of 161 articles in Discover Toxicology finds that pesticides with different mechanisms of action cause memory and learning impairments. These effects are noted in nontarget species including humans. Pesticide “[e]xposure during development, as well as chronic environmental and occupational exposure, can contribute to decreased cognitive performance,” the researchers say. With a focus on organophosphate pesticides, synthetic pyrethroids, and neonicotinoid insecticides, the authors highlight neurological impacts. Both learning and memory are crucial for the survival of many species. “Considering the importance of learning and memory for human and non-human animal behavior and the growing association between pesticide exposure and cognitive impairment, the aim of this review was to describe the studies showing the impact of pesticide exposure on memory and learning abilities in nontarget species, providing evidence of the impact of pesticides in central nervous system function,” the researchers state. The 161 articles included in the review were identified through database searches in PubMed/Medline and Scielo. The authors note, “Inclusion criteria for article selection included all articles published in English between 2015 and 2024 containing original studies in animals or humans with single or multiple pesticides exposure.” The articles consist of 132 preclinical […]

(Beyond Pesticides, December 10, 2024) Scientists from the Engineering Research Center of Protection and Utilization of Plant Resources at Shenyang Agricultural University in China reveal adverse effects of imidacloprid on soil communities in a study published in Pesticide Biochemistry and Physiology. The researchers highlight risks to nematodes from imidacloprid exposure in maize soil, as well as potential resistance mechanisms that impact not only nematode populations but also overall soil health. Maize, or corn, a productive crop grown worldwide, is a source of food and biofuel. In assessing the soil and species in maize fields after exposure to imidacloprid at various concentrations, the study researchers assess the impact of neonicotinoid insecticides on nontarget organisms and the health of soil communities. The assessment includes an evaluation of nematodes’ survival, growth, reproduction, and chemotaxis/locomotion behavior. With a statistical analysis of lipid and lipofuscin accumulation, acetylcholinesterase (an enzyme necessary for neurotransmission) activity, and gene expression levels, the study results show that imidacloprid induces: significantly reduced abundance and diversity of nematode species. negative effects on body length, reproduction, locomotion, lipid accumulation, lipofuscin accumulation, and acetylcholinesterase activity in Caenorhabditis elegans ( elegans). the upregulation of gpa-1, cyp-35a2, fat-2, fat-6, hsp-16.41, and hsp-16.2, along with the downregulation […]

(Beyond Pesticides, December 6, 2024) On December 2, the U.S. Environmental Protection Agency (EPA) announced yet another milestone in the convoluted life span of the insecticide chlorpyrifos. Under the deceptive headline “EPA Proposes Rule to Revoke Most Food Uses of the Insecticide Chlorpyrifos,” EPA stated that it is improving environmental protection by revoking all usages of chlorpyrifos except for 11 food and feed crops. The proposal was deemed “unconscionable” by Beyond Pesticides executive director Jay Feldman in an article in The New Lede. EPA claims this plan would reduce annual chlorpyrifos application by 70% compared to “historical usage.” Chlorpyrifos is a known neurological and reproductive toxicant. EPA has been cutting back on approved uses for years but is far behind other environmental authorities—the European Food Safety Authority and Thailand have banned it altogether, and California has banned its agricultural use. The trouble with EPA’s latest attempt is that it does nothing to clarify and rationalize EPA’s process, and it will not protect the public, because those 11 remaining products are among the most extensively grown and used in the world: soybeans, sugar beets, cotton, wheat, apples, citrus fruits, strawberries, alfalfa, cherries, peaches, and asparagus. Chlorpyrifos is an organophosphate chemical. These […]

(Beyond Pesticides, November 26, 2024) A study in Environment International finds that young children who exhibit higher levels of pesticide metabolites in their urine show more pronounced neurobehavioral problems at the age of ten. Researchers in China document how exposure during early childhood, especially during the sensitive window before the age of two, is linked to hyperactivity/inattention problems such as attention deficit hyperactivity disorder (ADHD). While adding to the body of science connecting pesticide exposure to learning and developmental disorders, this study offers a “novel perspective on characterizing the fluctuation in repeated measurements of multiple environmental chemicals and identifying the potential critical windows,” the authors share. (See previous Daily News coverage here, here, and here.) The researchers analyze data from questionnaires and urine samples through the ongoing Sheyang Mini Birth Cohort Study (SMBCS), which is a long-term prospective cohort study that associates environmental chemical exposure during pregnancy and childhood to negative health effects. This data addresses combined pesticide exposures in young children with neurobehavior analyses at the age of ten to determine any correlation. Within the SMBCS, a total of 1303 pregnant women are enrolled. When the children reached ages one, two, three, six, seven, eight, nine, and ten years […]

(Beyond Pesticides, November 22, 2024) With numerous campaigns at the state and federal level to ban the weed killer paraquat and nearly 6,000 individual lawsuits alleging exposure to it causes Parkinson’s disease (PD), U.S. Senator Cory Booker (D-NJ) and six Senators on October 31 called on the U.S. Environmental Protection Agency (EPA) to ban the chemical. Citing that “[f]armworkers and rural residents are disproportionately exposed to paraquat,” the Senators’ letter to EPA stating that, “Paraquat has been linked to Parkinson’s disease, thyroid cancer, and other health harms such as kidney, liver, and respiratory damage, and reproductive harm, including neurodevelopmental impact on developing fetuses [and] [i]n rural areas, exposure to paraquat and other pesticides during pregnancy can increase the risk of leukemia.” Most of the 6,000 cases against paraquat’s manufacturer, Syngenta, have been consolidated into Multi-District Litigation (MDL) in the U.S. District Court for the Southern District of Illinois. In April, the MDL judge ousted the plaintiffs’ expert witness regarding causality, which resulted in the first five cases ready for trial being tossed out. The defendant sells paraquat globally and is doing everything it can, according to investigative news reports, to discredit any link between paraquat and Parkinson’s, including the use […]

(Beyond Pesticides, November 19, 2024) Researchers at Stanford University recently published a study in Cancer, an international interdisciplinary journal of the American Cancer Society (ACS), that reveals a correlation for numerous pesticides with increased prostate cancer occurrence and associated death. The study finds that exposure to 22 pesticides is positively associated with prostate cancer. The 22 pesticides include 2,4‐D, acephate, azoxystrobin, bifenthrin, carbaryl, chloropicrin, cloransulam‐methyl, cyhalothrin‐lambda, diflufenzopyr, diuron, glyphosate, hexazinone, linuron, methyl parathion, pendimethalin, propiconazole, sulfosate, thiamethoxam, thifensulfuron, tribenuron methyl, trifloxystrobin, and trifluralin. (See more on 2,4-D and cancer prevalence here and here.) As prostate cancer is a leading national health concern, the authors investigate agricultural pesticide exposure and compared it to prostate cancer incidence and mortality across counties in the contiguous U.S. “The geographic variation in prostate cancer incidence and mortality suggests that regional environmental factors, such as pesticide exposure, may contribute to the development of prostate cancer,” the researchers postulate. In comparing county‐level associations of 295 pesticides and prostate cancer reports, the authors were able to conduct an environment‐wide association study (EWAS) to determine any statistically significant links. “We acquired annual estimated total usage data (kg per county) for all pesticides reported and applied to agricultural crops grown […]

(Beyond Pesticides, November 18, 2024) With the reported appointment of former U.S. Representative Lee Zeldin (R-NY) to the position of Administrator of the U.S. Environmental Protection Agency (EPA), Senate confirmation hearings will be an important process that is intended to shine a light on individual nominations, the policies of an administration, and the science (or lack thereof) behind them. There have been reports in the media that the Trump administration may attempt to circumvent the “advice and consent” rule of the U.S. Senate by making recess appointments. Alexander Hamilton wrote in the Federalist Papers: No. 76 that Senate confirmation hearings act as a safeguard against the appointment of “unfit” officials. Numerous interviews and critiques are painting a picture of what the future holds for environmental protection and all that means for addressing the serious catastrophic threats of ongoing and escalating health, biodiversity, and climate crises. “Mr. Trump, who has called climate change a “hoax,” has targeted “every one” of Mr. Biden’s policies designed to transition the United States away from fossil fuels,” according to The New York Times reporting on June 26, 2024. The Guardian reported on October 1 after Hurricane Helene, “As the hurricane continued to ravage the region over […]

(Beyond Pesticides, November 13, 2024) A study in Chemosphere, conducted by researchers from the Institute of Biochemistry and Molecular Biology in Germany, reveals the varied lethal and sublethal effects of different glyphosate mixtures through tests on the South African clawed frog, Xenopus laevis (X. laevis). After exposing embryos to four glyphosate formulations, mortality, morphological defects, altered heartbeat rate, and impaired heart-specific gene expression are observed. Glyphosate, an herbicide and popular weed killer in many Roundup® products, is one of the most commonly detected pesticides in waterbodies worldwide, threatening aquatic organisms and overall biodiversity. This study investigates the effects of Glyphosat TF, Durano TF, Helosate 450 TF, and Kyleo, four formulations containing glyphosate, as compared to the effects of pure glyphosate on embryonic development in amphibians. The formulations consist of varying concentrations of the active ingredient glyphosate, as well as other active and inert ingredients. The authors share that, “Glyphosat TF contains 34% glyphosate and 10–20% d-glucopyranose, while Durano contains 39–44% glyphosate and 1–5% N–N-dimethyl-C12-C14-(even numbered)-alkyl-1-amines. In Helosate most of the ingredients are listed – 50–70% glyphosate, 1–10% isopropylamine, 1–3% lauryl dimethyl betaine, 0.25–1% dodecyl dimethylamine. Kyleo only lists the active ingredients glyphosate (27.9%) and 2,4-D (32%).” 2-cell stage embryos (early […]

(Beyond Pesticides, November 12, 2024) With revelations reported last month by Investigate Midwest and previously by The Guardian showing that Syngenta, the manufacturer and registrant of paraquat, kept secret scientific information on the weed killer’s adverse effects related to Parkinson’s disease, there is increasing concern that endocrine-disrupting properties have not been fully disclosed. Endocrine-disrupting synthetic chemicals, derived from fossil fuels, will be the focus of Session 2 of Beyond Pesticides 41st National Forum: Imperatives for a Sustainable Future on Thursday, November 14 from 1:00-3:00pm (EST). Keynote Speaker The keynote speaker, Tracey Woodruff, PhD, will address the scientific, health, and regulatory issues associated with societal reliance on these chemicals. Dr. Woodruff, a former U.S. Environmental Protection Agency (EPA) senior scientist and policy advisor, is the director of the Program on Reproductive Health and the Environment, and professor in the Department of Obstetrics, Gynecology, and Reproductive Sciences in the School of Medicine at the University of California San Francisco.  Roundtable Discussion Dr. Woodruff’s talk will be followed by a roundtable with panelists, including a former senior scientist focusing on ecosystem effects, a breast cancer activist, and a farmworker advocate who will share their experience and insight into both the regulation of hazardous materials […]

(Beyond Pesticides, November 8-11, 2024) On Veterans Day 2024 we honor those who have served the country and allies. In the 117th (2021-2022) U.S. Congress, legislators enacted The Sergeant First Class Heath Robinson Honoring Our Promise to Address Comprehensive Toxics Act of 2022 (PACT Act). Since the law passed just over two years ago, there has been just under 1.3 million total approved claims marking a roughly 75% approval rate for PACT Act related claims, according to Department of Veteran Affairs (VA) accounting of progress between August 10, 2022, and October 12, 2024 through its dedicated bimonthly VA PACT Act Performance Dashboard. The legacy of toxic burn pits (open air areas where the military has burned toxic waste) and other avenues for toxic exposure in military bases oversees, as well as within the United States in Hawai’i (See coverage on asbestos exposure continuously impacting veterans, as reported on by Honolulu Civil Beat) and Puerto Rico (See peer-reviewed literature review here on toxic heavy metals in International Journal of Environmental Research and Public Health), among other areas, comes at a time when the country assesses the ongoing impacts of a history that has been characterized by critics as colonial or imperialist. […]

(Beyond Pesticides, November 5, 2024) Published in the journal Frontiers in Toxicology, a recent study uncovers serious flaws in the pesticide registration process at the U.S. Environmental Protection Agency (EPA) with an in-depth evaluation of the agency’s failure to protect the public from the harmful effects of five neonicotinoid (neonic) insecticides—as mandated by the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and amendments, including Food Quality Protection Act (FQPA) of 1996. This coincides with EPA’s ongoing review to renew their approval for the next 15 years (set to be announced in 2025). The report is based on the first comprehensive assessment of unpublished rodent-based Developmental Neurotoxicity (DNT) studies, conducted between 2000-2003 and submitted by pesticide manufacturers as part of the registration process. All five neonicotinoids evaluated—acetamiprid, clothianidin, imidacloprid, thiacloprid, and thiamethoxam—are associated with significant shrinkage of brain tissue at the highest dosage, according to EPA data reports (see acetamiprid, clothianidin, imidacloprid, thiacloprid, and thiamethoxam). However, with little or no data regarding the chemicals’ impacts at low and mid-level dosages, EPA has either failed to find a “No Observed Adverse Effect Level” (NOAEL) or, seemingly at random, set the NOAEL at the mid-level dosage. The evaluation suggests that perinatal exposure to […]

(Beyond Pesticides, November 4, 2024) The U.S. Environmental Protection Agency (EPA) last week opened a public comment period on the regulation of endocrine-disrupting pesticides, a proposal that lays out a drawn-out 10-year process that is narrow in evaluating the underlying mechanism that causes endocrine disruption. The proposal, published in the Federal Register as a partial settlement agreement and consent decree, responds to a lawsuit filed by farmworker and health groups challenging the agency’s failure to test and regulate endocrine-disrupting pesticides. Earlier in the year, after over 25 years of delay following the 1996 Congressional mandate to determine whether pesticides disrupt the endocrine system of humans and other organisms, EPA issued a proposal for modifying its approach to the implementation of the Endocrine Disruptor Screening Program (EDSP).  The National Institutes of Environmental Health Sciences explains endocrine disruptors this way: “Endocrine-disrupting chemicals (EDCs) are natural or human-made chemicals that may mimic, block, or interfere with the body’s hormones, which are part of the endocrine system. These chemicals are associated with a wide array of health issues. . . Endocrine glands, distributed throughout the body, produce the hormones that act as signaling molecules after release into the circulatory system. The human body is […]

(Beyond Pesticides, October 29, 2024) STARTS TOMORROW—NATIONAL FORUM: IMPERATIVES FOR A SUSTAINABLE FUTURE. A legal victory in federal court is the latest in a series of attempts to force the U.S. Environmental Protection Agency (EPA) to fulfill the mandate given to it by Congress in 1996 to test all pesticides for their endocrine disrupting effects and regulate them accordingly. The case in the U.S. District Court for the Northern District of California was brought by the Center for Food Safety (CFS) and a collection of agricultural workers’ organizations, farmers’ groups, and pesticide activists. Beyond Pesticides wrote in 2019, EPA’s “Endocrine Disruptor Screening Program (EDSP) began, then virtually stopped, its review and regulation of endocrine disrupting pesticides, despite [its 1996 Congressional mandate] to develop a screening program within two years and then begin regulating.” (See timeline, Figure 2, p11.) After the release of a  a damning 2021 Office of Inspector General (OIG) report (see Beyond Pesticides’ reporting) on the agency’s lack of progress in protecting the population from potentially damaging endocrine disruption impacts of exposures to synthetic chemical pesticides (and other chemicals of concern), CFS wrote: “The 2021 [OIG] report included the shocking revelation that some EPA staff were instructed to function as […]

(Beyond Pesticides, October 28, 2024) STARTS WEDNESDAY—NATIONAL FORUM: IMPERATIVES FOR A SUSTAINABLE FUTURE. As scientific articles and regulatory reviews by the U.S. Environmental Protection Agency (EPA) focus on individual pesticides or families of pesticides and specific health outcomes associated with exposure, legislation introduced by U.S. Senator Cory Booker (D-NJ), S. 5084, Safe School Meals Act (SSMA), proposes a holistic response to the protection of children by banning pesticides in school lunches. While focused on the elimination of certain individual pesticides and other chemicals of known concern, the bill unilaterally allows children to be served food from certified organic farms. The overwhelmingly large body of scientific findings on the adverse effects of pesticides in the food that children eat in schools and generally. For example, last week Beyond Pesticides commented on EPA’s Draft Human Health and/or Ecological Risk Assessments for Several Pesticides, citing scientific findings that, “Neonicotinoids . . .have been found to affect mammalian nicotinic acetylcholine receptors (nAChRs) [which] are of critical importance to human brain function, especially during development and for memory, cognition, and behavior.” (See more here.) This month, Jennifer Sass, PhD, et al., in Frontiers in Toxicology, published a review of  unpublished rodent developmental neurotoxicity (DNT) studies […]